Food and Chemical Toxicology

Papers
(The TQCC of Food and Chemical Toxicology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Deriving a point of departure for assessing the skin sensitization risk of wearable device constituents with in vitro methods274
A target fishing study to spot possible biological targets of fusaric acid: Inhibition of protein kinase-A and insights on the underpinning mechanisms225
GIS based interpolation method to urinary metal concentrations in Malaysia141
Facile synthesis of Cu NPs@Fe3O4-lignosulfonate: Study of catalytic and antibacterial/antioxidant activities121
Cannabinoid residuals in tissues of lambs fed spent hemp biomass and consumer's exposure assessment120
Transcriptome and Metabolome analysis reveal HFPO-TA induced disorders of hepatic glucose and lipid metabolism in rat by interfering with PPAR signaling pathway117
Inhibition of reactive oxygen species generation by N-Acetyl Cysteine can mitigate male germ cell toxicity induced by bisphenol analogs112
Gut-gonad crosstalk in mice exposed to a “chemical cocktail” combining metabolomics and microbial profile by amplicon sequencing106
KoCVAM-led development of phototoxicity alternative test method using reconstructed human epidermis model (KeraSkin™)103
Anticancer and anti-inflammatory properties of mangiferin: A review of its molecular mechanisms97
Sustained high expression of NRF2 inhibits cell apoptosis in arsenite-transformed human keratinocytes96
Perchlorate in foodstuffs from South China and its implication for human dietary exposure95
Green synthesis of copper oxide nanoparticles using Abutilon indicum leaves extract and their evaluation of antibacterial, anticancer in human A549 lung and MDA-MB-231 breast cancer cells94
Update to RIFM fragrance ingredient safety assessment, methylcyclooctyl carbonate, CAS Registry Number 61699-38-591
RIFM fragrance ingredient safety assessment, 1,3-benzodioxole, 5-(diethoxymethyl)-, CAS Registry Number 40527-42-288
RIFM fragrance ingredient safety assessment, ethyl valerate, CAS Registry Number 539-82-285
Update to RIFM fragrance ingredient safety assessment, pentyl benzoate, CAS Registry Number 2049-96-981
RIFM fragrance ingredient safety assessment, 2(3H)-benzofuranone, hexahydro-3,6-dimethyl-, CAS Registry Number 92015-65-181
RIFM fragrance ingredient safety assessment, santalol, CAS Registry Number 11031-45-176
RIFM fragrance ingredient safety assessment, 2-heptyltetrahydrofuran, CAS Registry Number 2435-16-776
RIFM fragrance ingredient safety assessment, linalool oxide, CAS Registry Number 1365-19-175
Update to RIFM fragrance ingredient safety assessment, 9-decenyl acetate, CAS Registry Number 50816-18-774
RIFM fragrance ingredient safety assessment, 2,6,10-trimethylundeca-5,9-dienol, CAS Registry Number 24048-14-471
RIFM fragrance ingredient safety assessment, 2-methylpropyl 3-methylbutyrate, CAS Registry Number 589-59-370
RIFM fragrance ingredient safety assessment, ethyl 2,4,7-decatrienoate, CAS Registry Number 78417-28-469
RIFM fragrance ingredient safety assessment, acetaldehyde ethyl cis-3-hexenyl acetal, CAS Registry Number 28069-74-169
RIFM fragrance ingredient safety assessment, 2,3-diethyl-5-methylpyrazine, CAS Registry Number 18138-04-067
Update to RIFM fragrance ingredient safety assessment, α-amylcinnamaldehyde, CAS Registry Number 122-40-767
RIFM fragrance ingredient safety assessment, 2-methylpropyl 2-methylbutyrate, CAS Registry Number 2445-67-265
RIFM fragrance ingredient safety assessment, pyrazine, 2-methoxy-3-(4-methylpentyl)-, CAS Registry Number 68844-95-164
RIFM fragrance ingredient safety assessment, terpinyl formate, CAS Registry Number 2153-26-663
Update to RIFM fragrance ingredient safety assessment, 2H-inden-2-one, 1,3-dihydro-, CAS Registry Number 615-13-461
RIFM fragrance ingredient safety assessment, 2-sec-butylcyclohexanone, CAS Registry Number 14765-30-160
Update to RIFM fragrance ingredient safety assessment, terpinyl acetate (isomer mixture), CAS Registry Number 8007-35-060
Lung microbiota participated in fibrous microplastics (MPs) aggravating OVA-induced asthma disease in mice58
Update to RIFM fragrance ingredient safety assessment, 2-pentylcyclopentan-1-one, CAS Registry Number 4819-67-458
The comparison of biological effects of bacterial and synthetic melanins in neuroblastoma cells57
Utility of life stage-specific chemical risk assessments based on New Approach Methodologies (NAMs)57
Identification and characterization of the rat in-vivo and in-vitro metabolites of tazemetostat using LC-QTOF-MS57
2-Amino-3-methylimidazo[4,5-f]quinoline induced oxidative stress and inflammation via TLR4/MAPK and TLR4/NF-κB signaling pathway in zebrafish (Danio rerio) livers56
Effects of plant alkaloids on mitochondrial bioenergetic parameters53
Diisobutyl phthalate (DiBP)-induced male germ cell toxicity and its alleviation approach52
RIFM fragrance ingredient safety assessment, 2H-1,5-benzodioxepin-3(4H)-one, 7-(1-methylethyl)-, CAS Registry Number 950919-28-552
Succinate dehydrogenase inhibitors: in silico flux analysis and in vivo metabolomics investigations show no severe metabolic consequences for rats and humans52
Exposure to di-(2-ethylhexyl) phthalate reduces secretion of GDNF via interfering with estrogen pathway and downregulating ERK/c-fos signaling pathway in astrocytes52
Update to RIFM fragrance ingredient safety assessment, benzenepropanenitrile, 4-ethyl-α,α.-dimethyl-, CAS Registry Number 134123-93-651
RIFM fragrance ingredient safety assessment, amyl cinnamate, CAS Registry Number 3487-99-851
Estimation of the bio-accessibility of methylmercury from aquatic foods using a PBTK model with an approximate Bayesian computation method in Chinese pregnant women50
Learning and memory impairment and transcriptomic profile in hippocampus of offspring after maternal fructose exposure during gestation and lactation50
Gestational dibutyl phthalate exposure impairs primordial folliculogenesis in mice through autophagy activation and NOTCH2 signal interruption49
Two generation reproduction toxicity study of GmDREB3 gene modified wheat in Wistar rats49
Clastogenic effects of cigarette smoke and urethane and their modulation by olive oil, curcumin and carotenoids in adult mice and foetuses48
A multicolor sensing system for simultaneous detection of four foodborne pathogenic bacteria based on Fe3O4/MnO2 nanocomposites and the etching of gold nanorods48
Alpha-class glutathione S-transferases involved in the detoxification of aflatoxin B1 in ducklings48
A sensitive and fast approach for voltammetric analysis of bisphenol a as a toxic compound in food products using a Pt-SWCNTs/ionic liquid modified sensor47
A machine learning-driven approach for prioritizing food contact chemicals of carcinogenic concern based on complementary in silico methods46
Unexpected beta-amyloid production by middle doses of resveratrol through stabilization of APP protein and AMPK-mediated inhibition of trypsin-like proteasome activity in a cell model of Alzheimer's d46
Simultaneous determination of Allium compounds (Propyl propane thiosulfonate and thiosulfinate) in animal feed using UPLC-MS/MS46
Protective effects of rivaroxaban against cisplatin-induced testicular damage in rats: Impact on oxidative stress, coagulation, and p–NF–κB/VCAM-1 signaling46
Fritillaria thunbergii Miq. (Zhe Beimu): A review on its traditional uses, phytochemical profile and pharmacological properties45
Construction of modified screen-printed graphite electrode for the application in electrochemical detection of sunset yellow in food samples45
Ultrasensitive detection of food colorant sunset yellow using nickel nanoparticles promoted lettuce-like spinel Co3O4 anchored GO nanosheets45
Anoxybacillus flavithermus loaded ɣ-Fe2O3 magnetic nanoparticles as an efficient magnetic sorbent for the preconcentrations of Cu(II) and Mn(II)44
Safety and efficacy indicators of guarana and Brazil nut extract carried in nanoparticles of coenzyme Q10: Evidence from human blood cells and red earthworm experimental model44
Single cell RNA sequencing detects persistent cell type- and methylmercury exposure paradigm-specific effects in a human cortical neurodevelopmental model44
Inflammation, immunity and potential target therapy of SARS-COV-2: A total scale analysis review44
LDHA and LDHB overexpression promoted the Warburg effect in malignantly transformed GES-1 cells induced by N-nitroso compounds43
Green synthesized colloidal silver is devoid of toxic effects on primary human nasal epithelial cells in vitro43
Vitamin C-induced competitive binding of HIF-1α and p53 to ubiquitin E3 ligase CBL contributes to anti-breast cancer progression through p53 deacetylation42
The alternative analog plasticizer BPS displays similar phenotypic and metabolomic responses to BPA in HepG2 and INS-1E cells42
Therapeutic role of melatonin on acrylamide-induced hepatotoxicity in pinealectomized rats: Effects on oxidative stress, NF-κB signaling pathway, and hepatocellular proliferation42
NRF-2α and mitophagy underlie enhanced mitochondrial functions and biogenesis induced by T-2 toxin in GH3 cells41
RIFM fragrance ingredient safety assessment, citronellyl ethyl oxalate, CAS Registry Number 60788-25-241
Ferroptosis is involved in quercetin-mediated alleviation of Ochratoxin A-induced kidney damage40
Ameliorating effects of white mulberry on iron-overload-induced oxidative stress and liver fibrosis in Swiss albino mice40
Thrombosis and Haemostasis challenges in COVID-19 – Therapeutic perspectives of heparin and tissue-type plasminogen activator and potential toxicological reactions-a mini review40
The effect of isovitexin on lipopolysaccharide-induced renal injury and inflammation by induction of protective autophagy40
Bisphenol A and its analogue bisphenol S exposure reduce estradiol synthesis via the ROS-mediated PERK/ATF4 signaling pathway39
Update to RIFM fragrance ingredient safety assessment, 3-octyl acetate, CAS registry number 4864-61-339
Evaluation of cytotoxic and genotoxic effects of paclitaxel-loaded PLGA nanoparticles in neuroblastoma cells39
Glutamate - A multifaceted molecule: Endogenous neurotransmitter, controversial food additive, design compound for anti-cancer drugs. A critical appraisal39
RIFM fragrance ingredient safety assessment, exo-2-[(1,7,7-trimethylbicyclo[2.2.1]hept-2-yl)oxy]ethanol, CAS Registry Number 7070-15-739
Development of a novel ex vivo model for chemical ocular toxicity assessment and its applicability for hair straightening products38
No-observed adverse effect levels of deoxynivalenol and aflatoxin B1 in combination induced immune inhibition and apoptosis in vivo and in vitro38
Safety assessment for Tris(2,4-di-tert-butylphenyl) phosphite (Irgafos 168) used as an antioxidant and stabilizer in food contact applications38
Comprehensive profile of circRNAs in formaldehyde induced heart development38
Interactive effects of cadmium and titanium dioxide nanoparticles on hepatic tissue in rats: Ameliorative role of coenzyme 10 via modulation of the NF-κB and TNFα pathway38
Metabolic profiling of bisphenol A diglycidyl ether in vitro and in vivo38
Rodent and broiler feeding studies with maize containing genetically modified event DP-915635-4 show no adverse effects on health or performance37
Effect of quercetin and mirtazapine on spermatogenesis and testis structure in phenylhydrazine-induced hemolytic anemia mice: An experimental study37
Donepezil ameliorates gut barrier disruption in doxorubicin-treated rats37
Fumonisins and zearalenone fed at low levels can persist several days in the liver of turkeys and broiler chickens after exposure to the contaminated diet was stopped36
RIFM fragrance ingredient safety assessment, dihydrocoumarin, CAS Registry Number 119-84-636
Toosendanin induces hepatotoxicity via disrupting LXRα/Lipin1/SREBP1 mediated lipid metabolism36
Advancing the allergenicity assessment of new proteins using a text mining resource36
Kidney toxicity and transcriptome analyses of male ICR mice acutely exposed to the mushroom toxin α-amanitin35
Beneficial actions of esculentin-2CHa(GA30) on high sucrose-induced oxidative stress in Drosophila melanogaster35
Protective effect of alpha-lipoic acid on bisphenol A-induced learning and memory impairment in developing mice: nNOS and keap1/Nrf2 pathway35
Facile synthesis of biopolymer decorated magnetic coreshells for enhanced removal of xenobiotic azo dyes through experimental modelling35
Sex dependent alteration of epigenetic marks after chronic morphine treatment in mice organs35
Rosmarinic acid attenuates acrylamide induced apoptosis of BRL-3A cells by inhibiting oxidative stress and endoplasmic reticulum stress35
Wheat embryo globulin protects against acute alcohol-induced liver injury in mice35
RIFM fragrance ingredient safety assessment, heptyl acetate, CAS registry number 112-06-134
Trends of caffeine intake from food and beverage among Chinese adults: 2004–201834
Update to RIFM fragrance ingredient safety assessment, 3-(4-methylcyclohex-3-enyl)-3-butenyl acetate, CAS registry number 6819-19-834
Evaluation of the toxic effects of food additives, alone or in mixture, in four human cell models34
RIFM fragrance ingredient safety assessment, cyclohexanone 1,3-butylene glycol ketal, CAS Registry Number 6413-26-934
Update to RIFM fragrance ingredient safety assessment, ethyl isobutyrate, CAS registry number 97-62-134
Role of CYP2D6 polymorphisms in tramadol metabolism in a context of co-medications and overweight34
Preclinical toxicity evaluation of the novel anti-hypertensive compound KSD17901933
Mechanism of deoxynivalenol mediated gastrointestinal toxicity: Insights from mitochondrial dysfunction33
Anti-inflammatory action of betulin and its potential as a dissociated glucocorticoid receptor modulator33
Ferroptosis promotes valproate-induced liver steatosis in vitro and in vivo32
Metabolic reprogramming of corn oligopeptide in regulating sodium nitrite-induced canine hepatocyte injury via TGF/NF-κB signaling pathways and aminoacyl-tRNA biosynthesis32
Combined effects of TiO2 nanoparticle and fipronil co-exposure on microbiota in mouse intestine31
Potential (co-)contamination of dairy milk with AFM1 and MC-LR and their synergistic interaction in inducing mitochondrial dysfunction in HepG2 cells31
Update to RIFM fragrance ingredient safety assessment, 4-ethyloctanoic acid, CAS registry number 16493-80-431
Assessment of human health risk concerning edible plants contamination with toxic elements around functional and derelict mines30
RIFM fragrance ingredient safety assessment, ethyl 2-ethylhexanoate, CAS Registry Number 2983-37-130
RIFM fragrance ingredient safety assessment, 3,7-dimethyloct-6-en-3-ol, CAS registry number 18479-51-130
LncRNA OBFC2A modulated benzene metabolites-induced autophagy and apoptosis by interacting with LAMP230
Translational relevance for in vitro/in vivo models: A novel approach to mercury dosing30
Influence of refrigeration and freezing in Microcystins and Cylindrospermopsin concentrations on fish muscle of tilapia (Oreochromis niloticus) and tench (Tinca tinca)30
The effect of bisphenols on sex and thyroid hormone concentrations in cord blood among newborns30
In vitro and in vivo genotoxicity evaluation of ALP1018, a nanomineral food supplement30
Assessment of the genotoxic potential of mintlactone30
RIFM fragrance ingredient safety assessment, α-cyclohexylidene benzeneacetonitrile, CAS Registry Number 10461-98-029
RIFM fragrance ingredient safety assessment, 2-methyl-3-(1-oxopropoxy)-4H-pyran-4-one, CAS Registry Number 68555-63-529
RIFM fragrance ingredient safety assessment, 5,8-methano-2H-1-benzopyran, 6(or 7)-ethylideneoctahydro-, [4aR,5S,8S,8aS(or 4aR,5R,8S,8aR)]-rel-, CAS Registry Number 943723-15-729
Effects of Perilla frutescens var. acuta in amyloid β toxicity and Alzheimer's disease-like pathology in 5XFAD mice29
Investigation on the potential adverse outcome pathway of the sensitive endpoint for nephrotoxicity induced by gardenia yellow based on an integrated strategy using bioinformatics analysis and in vitr29
RIFM fragrance ingredient safety assessment, (+/-)-4-ethyloctanal, CAS Registry Number 58475-04-029
Predicting chemicals’ toxicity pathway of female reproductive disorders using AOP7 and deep neural networks29
RIFM fragrance ingredient safety assessment, p-tert-butylcyclohexanone, CAS Registry Number 98-53-329
Mechanistic study of cytochrome P450 enzyme-mediated cytotoxicity of psoralen and isopsoralen29
RIFM fragrance ingredient safety assessment, p-cresol, CAS Registry Number 106-44-529
RIFM fragrance ingredient safety assessment, 2-ethylfuran, CAS Registry Number 3208-16-028
RIFM fragrance ingredient safety assessment, cis-3-hexenyl methyl carbonate, CAS Registry Number 67633-96-928
Cannabidiol regulates the activation of hepatic stellate cells by modulating the NOX4 and NF-κB pathways28
Ouabain inhibitor rostafuroxin attenuates dextromethorphan-induced manic potential28
Isoliquiritin counteracts cadmium-induced intestinal damage in mice through enhancing intestinal barrier function and inhibiting apoptosis28
Editorial Board28
Equivalence tests for safety assessment of genetically modified crops using plant composition data27
RIFM fragrance ingredient safety assessment, 2-[(3,3,5-trimethylcyclohexyl)acetyl]cyclopentan-1-one, CAS Registry Number 84642-57-927
Update to RIFM fragrance ingredient safety assessment, 3-methylpentyl 2-methylisocrotonate, CAS Registry Number 53082-58-927
A comprehensive study of the genotoxic and anti-genotoxic effects of homocysteine in HUVECs and mouse bone marrow cells27
LCP1-mediated cytoskeleton alterations involve in arsenite-triggered malignant phenotype of human immortalized prostate stromal cells27
Dose addition in mixtures of compounds with dissimilar endocrine modes of action in in vitro receptor activation assays and the zebrafish sexual development test26
EGCG exposure during pregnancy affects uterine histomorphology in F1 female mice and the underlying mechanisms26
RIFM fragrance ingredient safety assessment, methyl vanillyl ether, CAS Registry Number 5533-03-926
Risk-benefit assessment of methylmercury and n-3 polyunsaturated fatty acids through fish intake by pregnant women in Shanghai, China: Findings from the Shanghai Diet and Health Survey26
RIFM fragrance ingredient safety assessment, 4-cyclopentadecen-1-one, CAS Registry Number 35720-57-126
RIFM fragrance ingredient safety assessment, isobutyraldehyde, CAS Registry Number 78-84-226
RIFM fragrance ingredient safety assessment, 3-methoxy-5-cresol, CAS Registry Number 3209-13-025
RIFM fragrance ingredient safety assessment, ethyl decanoate, CAS Registry Number 110-38-325
RIFM fragrance ingredient safety assessment, methyl butyrate, CAS registry number 623-42-725
Comparison of the safety and efficacy of fingolimod and tofacitinib in the zebrafish model of colitis25
RIFM fragrance ingredient safety assessment, acetoin, CAS Registry Number 513-86-025
RIFM fragrance ingredient safety assessment, geraniol, CAS registry number 106-24-125
Gallic, ellagic acids and their oral combined administration induce kidney, lung, and heart injury after acute exposure in Wistar rats25
RIFM fragrance ingredient safety assessment, ethanol, 2-(4-methylphenoxy)-1-(2-phenylethoxy)-, CAS Registry Number 72987-59-825
Editorial Board25
Effect of cold food storage techniques on the contents of Microcystins and Cylindrospermopsin in leaves of spinach (Spinacia oleracea) and lettuce (Lactuca sativa)25
RIFM fragrance ingredient safety assessment, Methyl octanoate, CAS Registry Number 111-11-524
RIFM fragrance ingredient safety assessment, α,α,6,6-tetramethylbicyclo[3.1.1]hept-2-ene-2-propionaldehyde, CAS Registry Number 33885-52-824
RIFM fragrance ingredient safety assessment, 5-hydroxy-4-methylhexanoic acid δ-lactone, CAS Registry Number 10413-18-024
MiR-93 alleviates DEHP plasticizer-induced neurotoxicity by negatively regulating TNFAIP1 and inhibiting ubiquitin-mediated degradation of CK2β24
Rno_circRNA_016194 might be involved in the testicular injury induced by long-term formaldehyde exposure via rno-miR-449a-5p mediated Atg4b activation24
RIFM fragrance ingredient safety assessment, ethyl 3-methyl-2-oxopentanoate, CAS Registry Number 26516-27-824
RIFM fragrance ingredient safety assessment, bis-(methylthio)methane, CAS Registry Number 1618-26-424
Editorial Board24
RIFM fragrance ingredient safety assessment, nerol, CAS Registry Number 106-25-224
RIFM fragrance ingredient safety assessment, 1-heptanethiol, CAS Registry Number 1639-09-424
Effect of propiconazole on neutrophil extracellular traps formation: Assessing the role of autophagy23
In vitro analysis of green synthesized copper nanoparticles using Chloroxylon swietenia leaves for dye degradation and antimicrobial application23
RIFM fragrance ingredient safety assessment, 2-pentenoic acid, 2-methyl-, (3Z)-3-hexen-1-yl ester, CAS Registry Number 76649-17-723
RIFM fragrance ingredient safety assessment, α-amylcinnamaldehyde dimethyl acetal, CAS Registry Number 91-87-223
RIFM fragrance ingredient safety assessment, naphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)-, CAS Registry Number 6790-58-523
RIFM fragrance ingredient safety assessment, 11-tridecen-6-one, 8,12-dimethyl-, CAS Registry Number 68141-18-423
RIFM fragrance ingredient safety assessment, ethyl 2-methyl-4-pentenoate, CAS Registry Number 53399-81-823
RIFM fragrance ingredient safety assessment, isoeugenyl methyl ether, CAS Registry Number 93-16-323
Microcystin-LR exposure interfered maintenance of colonic microenvironmental homeostasis in rat23
RIFM fragrance ingredient safety assessment, citronellyl tiglate, CAS Registry Number 24717-85-923
RIFM fragrance ingredient safety assessment, tricyclo[5.2.1.02,6]decan-8-one, CAS Registry Number 13380-94-423
Phenobarbital, a hepatic metabolic enzyme inducer, inhibits preneoplastic hepatic lesions with expression of selective autophagy receptor p62 and ER-phagy receptor FAM134B in high-fat diet-fed rats th23
RIFM fragrance ingredient safety assessment, 2,6-dimethyl-10-methylene-2,6,11-dodecatrienal, CAS registry number 17909-77-223
In vitro mutagenicity assessment of fried meat-based food from mass catering companies23
RIFM fragrance ingredient safety assessment, dihydrocarvyl acetate, CAS Registry Number 20777-49-523
RIFM fragrance ingredient safety assessment, octahydro-7-methyl-1,4-methanonaphtalen-6(2H)-one, CAS registry number 41724-19-023
RIFM fragrance ingredient safety assessment, 2-acetyl-3-methylpyrazine, CAS Registry number 23787-80-623
RIFM fragrance ingredient safety assessment, cadinene, CAS Registry Number 29350-73-022
L-theanine attenuates H2O2-induced inflammation and apoptosis in IPEC-J2 cells via inhibiting p38 MAPK signaling pathway22
RIFM fragrance ingredient safety assessment, cyclohexanol, 2-methoxy-4-propyl-, CAS Registry Number 23950-98-322
The potential developmental neurotoxicity of calcium cyclamate in CD rats22
RIFM fragrance ingredient safety assessment, hex-3-enyl acetate, CAS Registry Number 1708-82-322
RIFM fragrance ingredient safety assessment, 2-tridecanone, CAS Registry Number 593-08-822
Unveiling the mechanisms of trichloroethylene hypersensitivity syndrome: Exploring the role of connexin 43 gap junctions in severe skin damage22
RIFM fragrance ingredient safety assessment, 3,5,5-trimethyl-1-hexanol, CAS Registry Number 3452-97-922
Pelargonic acid vanillylamide alleviates hepatic autophagy and ER stress in hepatic steatosis model22
Update to RIFM fragrance ingredient safety assessment, 4-methylpentanoic acid, CAS Registry Number 646-07-122
Hepatotoxic evaluation of toosendanin via biomarker quantification and pathway mapping of large-scale chemical proteomics21
Inactivation of microglia dampens blood-brain barrier permeability and loss of dopaminergic neurons in paraquat-lesioned mice21
RIFM fragrance ingredient safety assessment, citronellyl formate, CAS Registry number 105-85-121
Firm evidence for the detoxification of senecionine-induced hepatotoxicity via N-glucuronidation in UGT1A4–humanized transgenic mice21
Editorial Board21
The “steric-like” inhibitory effect and mechanism of doxycycline on florfenicol metabolism: Interaction risk21
RIFM fragrance ingredient safety assessment, 2-acetylthiophene, CAS registry number 88-15-321
RIFM fragrance ingredient safety assessment, 2-(1,1-dimethylethyl)-4-methylcyclohexan-1-ol, CAS Registry Number 67634-11-121
RIFM fragrance ingredient safety assessment, 1H-indende-2-methanol, 2,3-dihydro-2,5-dimethyl-, CAS Registry Number 285977-85-721
RIFM fragrance ingredient safety assessment, spiro[1,3-dioxolane-2,8′(5′H)-[2H-2,4a]methanonaphthalene],hexahydro-1′,1′,5′,5′-tetramethyl-, [2′S-(2′α,4′aα,8′aα)]-, CAS Registry Number 154171-77-421
A 21-day safety evaluation of biotechnologically produced 3-fucosyllactose (3-FL) in neonatal farm piglets to support use in infant formulas21
RIFM fragrance ingredient safety assessment, glyceryl monooleate, CAS Registry Number 111-03-521
RIFM fragrance ingredient safety assessment, phenylacetaldehyde dimethyl acetal, CAS Registry Number 101-48-421
Editorial Board21
RIFM fragrance ingredient safety assessment, propyl isovalerate, CAS Registry Number 557-00-620
Update to RIFM fragrance ingredient safety assessment, cyclohexanecarboxylic acid, 1,4-dimethyl-, methyl ester, trans-, CAS registry number 23250-42-220
RIFM fragrance ingredient safety assessment, acetaldehyde cyclic propylene glycol acetal, CAS Registry Number 3390-12-320
RIFM fragrance ingredient safety assessment, dihydroisocaryophyllene epoxide, CAS Registry Number 1209-61-620
Cashmeran as a potential endocrine disrupting chemical: What does the weight-of-the-evidence indicate?20
RIFM fragrance ingredient safety assessment, 2,6,6-trimethyl-1&2-cyclohexen-1-carboxaldehyde, CAS Registry Number 432-25-720
RIFM fragrance ingredient safety assessment, 2-phenoxyethyl propionate, CAS Registry Number 23495-12-720
Epigallocatechin-gallate attenuates rapamycin exacerbated high fat diet-induced autophagy, hormonal dysregulation, testicular and brain oxidative stress, and neurochemical changes in rats20
RIFM fragrance ingredient safety assessment, cyclohexanone diethyl ketal, CAS Registry Number 1670-47-920
RIFM fragrance ingredient safety assessment, styrene, CAS Registry Number 100-42-520
RIFM fragrance ingredient safety assessment, 3,7-dimethyl-1,3,6-octatriene, CAS registry number 13877-91-320
Update to RIFM fragrance ingredient safety assessment, benzyl acetate, CAS Registry Number 140-11-420
RIFM fragrance ingredient safety assessment, spiro[bicyclo[4.1.0]heptane-2,5'-[1,3]dioxane], 2′,2′,3,7,7-pentamethyl-, (1α,3α,6α)-, CAS Registry number 121251-67-020
RIFM fragrance ingredient safety assessment, p-propylanisole, CAS Registry Number 104-45-019
Neuroprotective mechanisms of multitarget 7-aminophenanthridin-6(5H)-one derivatives against metal-induced amyloid proteins generation and aggregation19
RIFM fragrance ingredient safety assessment, S-(1-methylpropyl) 3-methylbut-2-enethioate, CAS Registry Number 34322-09-319
In vitro-in vivo correlation of the chiral pesticide prothioconazole after interaction with human CYP450 enzymes19
Update to RIFM fragrance ingredient safety assessment, tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran, CAS Registry Number 16409-43-119
RIFM fragrance ingredient safety assessment, 2-hexanol, CAS Registry Number 626-93-719
Fluorene-9-bisphenol exposure damages the testis in mice through a novel mechanism of ferroptosis19
The food additive xylitol enhances the butyrate formation by the child gut microbiota developed in a dynamic colonic simulator19
RIFM fragrance ingredient safety assessment, δ-dodecalactone, CAS Registry Number 713-95-119
Geniposide alleviated hydrogen peroxide-induced apoptosis of human hepatocytes via altering DNA methylation19
Update to RIFM fragrance ingredient safety assessment, p-(2,2-dimethoxyethyl)toluene, CAS Registry Number 42866-91-119
RIFM fragrance ingredient safety assessment, acetanisole, CAS Registry Number 100-06-119
Update to RIFM fragrance ingredient safety assessment, ethylene brassylate, CAS Registry Number 105-95-319
Update to RIFM fragrance ingredient safety assessment, 3,7-dimethyl-1,6-nonadien-3-ol, CAS Registry Number 10339-55-619
RIFM fragrance ingredient safety assessment, benzyl valerate, CAS Registry Number 10361-39-419
RIFM fragrance ingredient safety assessment, isopentyl 2-methylcrotonate (E), CAS Registry Number 41519-18-019
RIFM fragrance ingredient safety assessment, farnesyl acetate, CAS Registry Number 29548-30-919
RIFM fragrance ingredient safety assessment, 2-methoxy-3-methylpyrazine, CAS Registry Number 2847-30-519
RIFM fragrance ingredient safety assessment, 2-decenal, CAS registry number 3913-71-118
Update to RIFM fragrance ingredient safety assessment, benzyl butyrate, CAS Registry Number 103-37-718
Zearalenone promotes porcine ESCs apoptosis by enhancing Drp1-mediated mitochondrial fragmentation and activating the JNK pathway18
RIFM fragrance ingredient safety assessment, 4-(2,4,6-trimethyl-3-cyclohexen-1-yl)-3-buten-2-one, CAS Registry Number 67801-38-118
RIFM fragrance ingredient safety assessment, o-(Methylthio)-phenol, CAS Registry Number 1073-29-618
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