Food and Chemical Toxicology

Article	Citations
RIFM fragrance ingredient safety assessment, acetaldehyde ethyl cis-3-hexenyl acetal, CAS Registry Number 28069-74-1	327
Update to RIFM fragrance ingredient safety assessment, 3-methylbutanal diethyl acetal, CAS Registry Number 3842-03-3	236
Editorial Board	196
Investigation and evaluation of gastrointestinal toxicity biomarkers in rats with different sites of gastrointestinal injury	148
Editorial Board	135
Update to RIFM fragrance ingredient safety assessment, 3-tert-butylcyclohexyl acetate, CAS Registry Number 31846-06-7	123
RIFM natural complex substance (NCS) fragrance ingredient safety assessment, lavandin abrialis, CAS registry number 8022-15-9, RIFM ID 1048554	121
Substance depletion of monoterpenes in the mouse lymphoma assay: Quantification, impact and mitigation	113
Functional evaluation of fibroblast-to-myofibroblast transition as an in vitro screening tool for pulmonary fibrosis	102
From food-to-human microplastics and nanoplastics exposure and health effects: A review on food, animal and human monitoring data	99
Acrylamide in food: Occurrence, metabolism, molecular toxicity mechanism and detoxification by phytochemicals	95
Diisobutyl phthalate (DiBP)-induced male germ cell toxicity and its alleviation approach	94
MiR-93 alleviates DEHP plasticizer-induced neurotoxicity by negatively regulating TNFAIP1 and inhibiting ubiquitin-mediated degradation of CK2β	93
Lithium suppresses the Ras-Raf-MEK-ERK signaling in CD4 T cells and impairs the humoral immune system	92
Low-dose benzo[a]pyrene exposure induces hepatic lipid deposition through LCMT1/PP2Ac-mediated autophagy inhibition	78
The role of GSK3β signaling mediated lysosomal biosynthesis dysregulation in fluoride-induced neurological impairment	76
Gene expression profiles related to apoptosis and levels of DNA oxidative damage in primary dermal fibroblast cells (ATCC® PCS-201-012TM) treated with zirconium oxide nanoparticles	73
The “steric-like” inhibitory effect and mechanism of doxycycline on florfenicol metabolism: Interaction risk	71
Assessing the toxic dose of the potent antioxidant 3,5-dihydroxy-4-methoxybenzyl alcohol in rats	71
Curcumin mitigates gentamicin induced-renal and cardiac toxicity via modulation of Keap1/Nrf2, NF-κB/iNOS and Bcl-2/BAX pathways	70
Kidney toxicity and transcriptome analyses of male ICR mice acutely exposed to the mushroom toxin α-amanitin	70
Toxic effects of 5-hydroxymethylfurfural on intestinal epithelial cell and its impact on the expression of MAPK pathway-related genes	69
TLR4 knockout ameliorates acute LPS-sensitized tolvaptan-induced idiosyncratic liver injury by disrupting drug metabolism, inflammation, and bile acid homeostasis	69
Assessment of human health risk concerning edible plants contamination with toxic elements around functional and derelict mines	66
Tectorigenin ameliorated high-fat diet-induced nonalcoholic fatty liver disease through anti-inflammation and modulating gut microbiota in mice	62

EGCG exposure during pregnancy affects uterine histomorphology in F1 female mice and the underlying mechanisms	62
Rutin, a natural flavonoid glycoside, ameliorates zearalenone induced liver inflammation via inhibiting lipopolysaccharide gut leakage and NF-κB signaling pathway in mice	60
Update to RIFM fragrance ingredient safety assessment, octyl butyrate, CAS Registry Number 110-39-4	59
RIFM fragrance ingredient safety assessment, furfural, CAS Registry Number 98-01-1	57
Update to RIFM fragrance ingredient safety assessment, 1-naphthalenol, 1,2,3,4,4a,5,8,8a-octahydro-2,2,6,8-tetramethyl-, CAS Registry Number 103614-86-4	57
RIFM fragrance ingredient safety assessment, 2-methylpropyl 2-methylbutyrate, CAS Registry Number 2445-67-2	57
RIFM fragrance ingredient safety assessment, ethyl 2-ethylhexanoate, CAS Registry Number 2983-37-1	57
RIFM fragrance ingredient safety assessment, bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-, benzoate, CAS Registry Number 55066-54-1	56
RIFM fragrance ingredient safety assessment, ethyl valerate, CAS Registry Number 539-82-2	55
Update to RIFM fragrance ingredient safety assessment, 2H-inden-2-one, 1,3-dihydro-, CAS Registry Number 615-13-4	54
Update to RIFM fragrance ingredient safety assessment, pentyl benzoate, CAS Registry Number 2049-96-9	52
Update to RIFM fragrance ingredient safety assessment, 4-methylpentanoic acid, CAS Registry Number 646-07-1	52
RIFM fragrance ingredient safety assessment, 3-buten-2-one, 4-(2,2,3-trimethyl-6-methylenecyclohexyl)-, CAS registry number 79-68-5	51
RIFM fragrance ingredient safety assessment, styrene, CAS Registry Number 100-42-5	51
RIFM fragrance ingredient safety assessment, o-(Methylthio)-phenol, CAS Registry Number 1073-29-6	50
RIFM fragrance ingredient safety assessment, isopentyl 2-methylcrotonate (E), CAS Registry Number 41519-18-0	49
Editorial Board	49
RIFM fragrance ingredient safety assessment, 2-pentylcyclopentan-1-ol, CAS Registry Number 84560-00-9	49
RIFM fragrance ingredient safety assessment, isoeugenyl methyl ether, CAS Registry Number 93-16-3	48
RIFM fragrance ingredient safety assessment, 2-acetyl-3-methylpyrazine, CAS Registry number 23787-80-6	48
Update to RIFM fragrance ingredient safety assessment, hexyl isovalerate, CAS Registry Number 10032-13-0	48
RIFM fragrance ingredient safety assessment, methyl butyrate, CAS registry number 623-42-7	48
Comparative detection of E. coli, B. subtilis and their mixture in yam samples by ATP bioluminescence and SERS methods	46
Toxicity assessment of heavy metals translocation in maize grown in the Ganges delta floodplain soils around the Payra power plant in Bangladesh	46
Inhalation toxicity of thermal transformation products formed from e-cigarette vehicle liquid using an in vitro lung model exposed at the Air–Liquid Interface	45
Global review, meta-analysis and health risk assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in chicken kebab using Monte Carlo simulation method	44
Gut-gonad crosstalk in mice exposed to a “chemical cocktail” combining metabolomics and microbial profile by amplicon sequencing	44
Ultra-fast liquid chromatography detection of β-N-methylamine-l-alanine and its isomers in cycad seeds and cyanobacterial symbionts for neurotoxic risk assessment	44
Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway	43
Exploring time dependent trends and risks of pyrrolizidine alkaloids and their N-oxides in food	43
RIFM fragrance ingredient safety assessment, ethyl decanoate, CAS Registry Number 110-38-3	43
Microcystin-LR exposure interfered maintenance of colonic microenvironmental homeostasis in rat	43
Inhibition of human sulfotransferases (SULTs) by per- and polyfluoroalkyl substances (PFASs) and structure-activity relationship	43
Identification of non-volatile non-intentionally added substances from polyester food contact coatings and genotoxicity assessment of polyester coating's migrates	43
Predicting chemicals’ toxicity pathway of female reproductive disorders using AOP7 and deep neural networks	42
Preclinical toxicity evaluation of the novel anti-hypertensive compound KSD179019	42
Sustained high expression of NRF2 inhibits cell apoptosis in arsenite-transformed human keratinocytes	42
No-observed adverse effect levels of deoxynivalenol and aflatoxin B1 in combination induced immune inhibition and apoptosis in vivo and in vitro	42
Health risks associated with the consumption of shrimp and squid contaminated with heavy metals in Poland	41
Probiotic lactobacilli attenuate oxysterols-induced alteration of intestinal epithelial cell monolayer permeability: Focus on tight junction modulation	41
Evaluation of cigarette smoke-induced oxidative stress and inflammation in BEAS-2B cells based on a lung microfluidic chip	41
Preclinical safety evaluation of sodium l-methylfolate	41
Sinomenine synergistically enhances 5-Fu anticancer effects in oral cancer through modulating the miR-140-5p-PDK1-anaerobic glycolysis pathway	41
Gallic, ellagic acids and their oral combined administration induce kidney, lung, and heart injury after acute exposure in Wistar rats	40
Integrated approaches to testing and assessment for the endocrine disrupting activity of tartrazine based on adverse outcome pathways and OECD frameworks	40
NRF-2α and mitophagy underlie enhanced mitochondrial functions and biogenesis induced by T-2 toxin in GH3 cells	40
Theaflavin alleviates cisplatin-induced nephrotoxicity: Targeting SIRT1/p53/FOXO3a/Nrf2 signaling and the NF-kB inflammatory cascade	40
Bisphenol A and its analogue bisphenol S exposure reduce estradiol synthesis via the ROS-mediated PERK/ATF4 signaling pathway	39
Combined environmental relevant exposure to perfluorooctanoic acid and zinc sulfate enhances apoptosis through binding with endogenous antioxidants in Daphnia magna	39
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice	39

Cardiac oxylipin perturbances in response to 2-monochloropropane-1,3-diol exposure are ameliorated by dietary adequacy of the essential n-3 fatty acid, α-linolenic acid	39
RIFM fragrance ingredient safety assessment, acetylcarene, CAS Registry Number 3608-11-5	38
Farnesol prevents chlorpyrifos nephrotoxicity by modulating inflammatory mediators, Nrf2 and FXR and attenuating oxidative stress	38
In response to the Letter to the Editor from Xiao regarding our article, “FEMA GRAS assessment of natural flavor complexes: Asafetida oil, garlic oil and onion oil”	38
RIFM fragrance ingredient safety assessment, α-hexylcinnamaldehyde, CAS Registry Number 101-86-0	38
Alcohol induces hepatocytes necroptosis through the LC3/RIPK1/RIPK3 pathway	37
Mitigating Bisphenol-Induced Neurotoxicity: Exploring the Therapeutic Potential of Diosmin in Zebrafish Larvae	37
N-(2-ozoazepan-3-yl)-pyrrolidine-2-carboxamide, a novel Octopus vulgaris ink-derived metabolite, exhibits a pro-apoptotic effect on A549 cancer cell line and inhibits pro-inflammatory markers	37
Melatonin protects against diclofenac induced oxidative stress mediated myocardial toxicity in rats: A mechanistic insight	37
Organophosphate esters and their metabolites in Beijing total diets: Occurrence, time trend, and dietary exposure assessment	37
Update to RIFM fragrance ingredient safety assessment, nonyl acetate, CAS registry number 143-13-5	36
Development and application of an interactive generic physiologically based pharmacokinetic (igPBPK) model for adult beef cattle and lactating dairy cows to estimate tissue distribution and edible tis	36
Characterizing the risk related to the exposure to methylmercury over a lifetime: A global approach using population internal exposure	36
Probiotic cultures as a potential protective strategy against the toxicity of environmentally relevant chemicals: State-of-the-art knowledge	36
Epigallocatechin gallate-rich fraction alleviates histamine-induced neurotoxicity in rats via inactivating caspase-3/JNK signaling pathways	36
Beyond monitoring: Integrating risk, benefit, and biomonitoring in Greek dietary exposure to dioxins and PCBs	36
Deoxynivalenol upregulates hypoxia-inducible factor-1α to promote an “immune evasion” process by activating STAT3 signaling	36
RIFM fragrance ingredient safety assessment, dodecahydro-3,8,8,11a-tetramethyl-5H-3,5a-epoxynaphth[2,1-c]oxepin, CAS Registry Number 57345-19-4	35
RIFM fragrance ingredient safety assessment, 2,4,4,7-tetramethylnona-6,8-diene-3-one-oxime, CAS Registry Number 81783-01-9	35
RIFM fragrance ingredient safety assessment, germacrene D, CAS Registry Number 23986-74-5	35
RIFM fragrance ingredient safety assessment, cycloionone, CAS Registry Number 5552-30-7	35
Update to RIFM fragrance ingredient safety assessment, methyl benzoate, CAS Registry Number 93-58-3	35
RIFM fragrance ingredient safety assessment, p-isopropyl phenylacetaldehyde, CAS Registry Number 4395-92-0	35
Update to RIFM fragrance ingredient safety assessment, linalyl acetate, CAS registry number 115-95-7	34
Update to RIFM fragrance ingredient safety assessment, methyl phenylacetate, CAS Registry Number 101-41-7	34
RIFM fragrance ingredient safety assessment, 3-(p-isopropylphenyl)propionaldehyde, CAS registry number 7775-00-0	34
RIFM fragrance ingredient safety assessment, cis- and trans-p-1(7),8-menthadien-2-yl acetate, CAS registry number 71660-03-2	34
RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, tangelo oil, expressed, CAS Registry Number 72869-73-9, RIFM ID 931-G2.5	34
Update to RIFM fragrance ingredient safety assessment, p-tolyl alcohol, CAS Registry Number 589-18-4	34
RIFM fragrance ingredient safety assessment, 3-phenyl-3-buten-1-yl acetate, CAS Registry Number 7306-12-9	34
RIFM fragrance ingredient safety assessment, ω-6-hexadecenlactone, CAS Registry Number 7779-50-2	33
Update to RIFM fragrance ingredient safety assessment, ethyl benzoate, CAS Registry Number 93-89-0	32
RIFM fragrance ingredient safety assessment, o-methoxybenzaldehyde, CAS Registry Number 135-02-4	32
RIFM fragrance ingredient safety assessment, 4-acetoxy-2,5-dimethyl-3(2H)furanone, CAS Registry Number 4166-20-5	32
RIFM fragrance ingredient safety assessment, patchouli alcohol, CAS Registry Number 5986-55-0	32
RIFM fragrance ingredient safety assessment, cedryl formate, CAS Registry Number 39900-38-4	31
Toxicology of Dyes: Editorial Introduction	31
RIFM fragrance ingredient safety assessment, (1aα,4α,7aα)-1a,3,3,4,6,6-hexamethyl-1a,2,3,4,5,6,7,7a-octahydronapth[3,3-b]oxirene, CAS Registry Number 94400-98-3	31
Piceatannol upregulates USP14-mediated GPX4 deubiquitination to inhibit neuronal ferroptosis caused by cerebral ischemia-reperfusion in mice	31
In silico and in vitro safety assessment of a fungal biomass from Rhizomucor pusillus for use as a novel food ingredient	30
Non-allergenic mixed T cell epitope peptides for preventing Scy p 9 allergic reactions	30
Association between Di-2-ethylhexyl phthalate and nonalcoholic fatty liver disease among US adults: Mediation analysis of body mass index and waist circumference in the NHANES	30
Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan	30
RIFM fragrance ingredient safety assessment, benzoic acid, 2-[[3-(4-methoxyphenyl)-2-methylpropylidene]amino]-, methyl ester, CAS registry number 111753-62-9	30
Update to RIFM fragrance ingredient safety assessment, isobutyl propionate, CAS Registry Number 540-42-1	30
Glyphosate and AMPA-induced apoptosis and epigenetic alterations in HepG2 Cells: Upregulation of p53-BAX-CASP pathways	30
Update to RIFM fragrance ingredient safety assessment, menthyl acetate (isomer unspecified), CAS registry number 16409-45-3	30
Chronic exposure to B[a]P induces malignant transformation of breast epithelial cells through the mechanism via TGF-β signaling pathway	30
Environmental toxicity risk evaluation of nitroaromatic compounds: Machine learning driven binary/multiple classification and design of safe alternatives	30
Unravelling the anti-inflammatory and antioxidant effects of standardized green and black caffeinated coffee, tea, and their mixtures in an obese male rat model: Insights from biochemical, metabolomic	30
RIFM fragrance ingredient safety assessment, phenethyl propionate, CAS Registry Number 122-70-3	30
RIFM fragrance ingredient safety assessment, benzene, 1-(dimethoxymethyl)-4-methoxy-, CAS Registry Number 2186-92-7	29
RIFM fragrance ingredient safety assessment, oxacyclopentadec-10-en-2-one, 13-methyl-, CAS Registry Number 329925-33-9	29
RIFM fragrance ingredient safety assessment, 2-phenylhexanenitrile, CAS registry number 3508-98-3	29
RIFM fragrance ingredient safety assessment, bisabolene, CAS registry number 495-62-5	29
RIFM fragrance ingredient safety assessment, 1-formyl-1-methyl-4-(4-methyl-pentyl)-3-cyclohexene, CAS Registry Number 66327-54-6	29
RIFM fragrance ingredient safety assessment, 4-methoxy-α-methylbenzenepropanal, CAS Registry Number 5462-06-6	29
RIFM fragrance ingredient safety assessment, 3-mercaptohexyl acetate, CAS Registry Number 136954-20-6	28
RIFM fragrance ingredient safety assessment, 2-ethylhexanal, CAS Registry Number 123-05-7	28
Update to RIFM fragrance ingredient safety assessment, α,2,2,3-tetramethylcyclopent-3-ene-1-butyraldehyde, CAS Registry Number 65114-03-6	28
RIFM fragrance ingredient safety assessment, 1,1-dimethyl-2-phenylethyl acetate, CAS registry number 151-05-3	28
Editorial Board	28
Update to RIFM fragrance ingredient safety assessment, trans-2-hexenoic acid, CAS Registry Number 13419-69-7	28
RIFM fragrance ingredient safety assessment, ethyl butyrate, CAS registry number 105-54-4	28
Emamectin benzoate-induced toxicity affects intestinal epithelial integrity involving apoptosis	27
RIFM fragrance ingredient safety assessment, d,l-menthone 1,2-glycerol ketal, CAS Registry Number 63187-91-7	27
Corrigendum to “Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway” [Food and Chemical Toxico	27
Corrigendum to “Effects of gelatin-based antifreeze peptides on cell viability and oxidant stress of Streptococcus thermophilus during cold stage” [Food Chem. Toxicol. 136 (2020) 111056]	27
RIFM fragrance ingredient safety assessment, sssmenthadiene-7-methyl formate, CAS registry number 68683-20-5	27
Impact of food matrices on the characteristics and cellular toxicities of ingested nanoplastics in a simulated digestive tract	27
Fertility-enhancing effects of inositol & vitamin C on cisplatin induced ovarian and uterine toxicity in rats via suppressing oxidative stress and apoptosis	27
Apigenin in cancer therapy: From mechanism of action to nano-therapeutic agent	27
Active compounds of licorice ameliorate microplastics-induced intestinal damage by targeting FADD	27
Immunoproteasome subunit PSMB8 regulates microglia-mediated neuroinflammation upon manganese exposure by PERK signaling	26
Rapid identification of counterfeited beef using deep learning-aided spectroscopy: Detecting colourant and curing agent adulteration	26
Multivariate analysis of potentially toxic metal contents in soil and vegetables: Enrichment, bioconcentration, translocation from soil to vegetables, and assessment of human health toxicity	26
Triptolide exposure triggers ovarian inflammation by activating cGAS-STING pathway and decrease oocyte quality in mouse	26
Hyperoside attenuates Cd-induced kidney injury via inhibiting NLRP3 inflammasome activation and ROS/MAPK/NF-κB signaling pathway in vivo and in vitro	26
Determination of acrylamide levels in chips/crisps on the Italian market and exposure risk assessment	26
Mycotoxins in raw materials, beverages and supplements of botanicals: A review of occurrence, risk assessment and analytical methodologies	26

Chlorinated organophosphorus flame retardants-induced mitochondrial abnormalities and the correlation with progesterone production in mLTC-1 cells	26
Update to RIFM fragrance ingredient safety assessment, 3-methyl-2-butenyl acetate, CAS Registry Number 1191-16-8	25
Experimental evaluation of favipiravir (T-705)-induced liver and kidney toxicity in rats	25
Weighted analysis of 2′-fucosyllactose, 3-fucosyllactose, lacto-N-tetraose, 3′-sialyllactose, and 6′-sialyllactose concentrations in human milk	25
Enniatin B and beauvericin affect intestinal cell function and hematological processes in Atlantic salmon (Salmo salar) after acute exposure	25
Liensinine, a alkaloid from lotus plumule, mitigates lipopolysaccharide-induced sepsis-associated encephalopathy through modulation of nuclear factor erythroid 2-related factor-mediated inflammatory b	25
Hyoscyamine induces developmental toxicity by disrupting metabolism in zebrafish embryo (Danio rerio)	25
New insights into mechanisms of valproic acid-induced neurodevelopmental toxicity in autism spectrum disorder: An integrative network toxicology approach combined with in vivo validation	25
CDKN1A promotes Cis-induced AKI by inducing cytoplasmic ROS production and ferroptosis	25
Kaempferol improves recurrent spontaneous abortion outcomes and prevents oxidative stress damage by inhibiting the NF-kB signaling pathway	25
Isochlorogenic acid A ameliorated lead-induced anxiety-like behaviors in mice by inhibiting ferroptosis-mediated neuroinflammation via the BDNF/Nrf2/GPX4 pathways	25
Bisphenol a exposure decreases learning ability through the suppression of mitochondrial oxidative phosphorylation in the hippocampus of male mice	25
RIFM fragrance ingredient safety assessment, 1-propanol, 2-methyl-3-[(1,7,7-trimethylbicyclo-[2.2.1]hept-2-yl)oxy]-, CAS Registry Number 128119-70-0	24
RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]deca-3,6-diene, 2,6,9,10-tetramethyl-, CAS Registry Number 71078-31-4	24
Update to RIFM fragrance ingredient safety assessment, benzyl formate, CAS Registry Number 104-57-4	24
Update to RIFM fragrance ingredient safety assessment, acetaldehyde, diphenethyl acetal, CAS Registry Number 122-71-4	24
RIFM fragrance ingredient safety assessment, methyl sorbate, CAS Registry Number 689-89-4	24
Acute ivermectin toxicity on skin and brain tissue of adult albino rats: Evaluation of the role of Flumazenil and Vitamin C as new treatment modalities	24
RIFM fragrance ingredient safety assessment, butyl salicylate, CAS Registry Number 2052-14-4	24
RIFM fragrance ingredient safety assessment, pyridine, 4-[1(4-,5 or 6)-methylbicyclo[2.2.1]hept-5-en-2-yl]-, CAS Registry Number 862079-91-2	24
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro	24
RIFM fragrance ingredient safety assessment, 3,3,5-trimethylcyclohexyl ethyl ether, CAS Registry Number 67583-77-1	23
RIFM fragrance ingredient safety assessment, thymol, CAS Registry Number 89-83-8	23
RIFM fragrance ingredient safety assessment, d-8-p-menthene-1,2-epoxide, CAS Registry Number 1195-92-2	23
Bisphenol analogues inhibit human and rat 17β-hydroxysteroid dehydrogenase 1: 3D-quantitative structure-activity relationship (3D-QSAR) and in silico docking analysis	23
Neurotoxicity of dibutyl phthalate in zebrafish larvae: Decreased energy acquisition by neurons	23
Chronic glucocorticoid exposure accelerates Aβ generation and neurotoxicity by activating calcium-mediated CN-NFAT1 signaling in hippocampal neurons in APP/PS1 mice	23
RIFM fragrance ingredient safety assessment, 11-oxahexadecanolide, CAS Registry Number 3391-83-1	23
Normolipidic diet containing deep-fried saturated and unsaturated fatty acids rich edible oils promotes metabolic dysregulation and inflammatory microenvironment in Wistar rats	23
RIFM fragrance ingredient safety assessment, methyl p-methylbenzoate, CAS Registry Number 99-75-2	23
Potential exacerbation of polycystic ovary syndrome by saccharin sodium Via taste receptors in a letrozole rat model	23
Exposure to short-, medium-, and long-chain chlorinated paraffins for infant via cow infant formula, goat infant formula and baby food	23
Dermal repeated dose toxicity study of the anti-breast cancer drug Formestane cream in Bama minipig	23
RIFM fragrance ingredient safety assessment, 3-hexanone, 5-mercapto-5-methyl-, CAS Registry Number 851768-51-9	23
Update to RIFM fragrance ingredient safety assessment, hexanoic acid, 4-methyl-, CAS registry number 1561-11-1	23
RIFM fragrance ingredient safety assessment, 3-phenylpropionaldehyde, CAS Registry Number 104-53-0	23
Bioactive extract of Morchella esculenta ameliorates cyclophosphamide-induced mitochondrial dysfunction and cardiotoxicity by modulating KEAP1/NRF2 and pro-inflammatory genes expression	23
The toxicity of lead on human neuroblastoma cells was alleviated by HUC-MSC-derived exosomes through miR-26a-5p/PTEN pathway	23
Carcinogenic and non-carcinogenic risks caused by rice contamination with heavy metals and their effect on the prevalence of cardiovascular disease (Using machine learning)	23
Fluquinconazole disrupts calcium and mitochondrial homeostasis, leading to bovine mammary epithelial cell death	23
Editorial Board	22
High fructose-induced skeletal muscle insulin resistance could be alleviated by berberine via AMPD1 and ADSL	22
RIFM fragrance ingredient safety assessment, 2,3,5-trimethylpyrazine, CAS registry number 14667-55-1	22
Maternal exposure to a glyphosate-based herbicide impairs placental development through endoplasmic reticulum stress in mice	22
RIFM fragrance ingredient safety assessment, isolongifolene oxide, CAS Registry Number 26619-69-2	22
In vitro toxicological assessment of aerosols from indirectly heated tobacco products using a solvent-free extraction method	22
Update to RIFM fragrance ingredient safety assessment, β-caryophyllene alcohol, CAS registry number 472-97-9	22
Safety and toxicologic evaluation of Edible Pongamia Oil: A novel food ingredient	22
Therapeutic potential of 2S-hesperidin against the hepatotoxic effects of dichlorvos in rats	22
Update to RIFM fragrance ingredient safety assessment, isoamyl hexanoate, CAS registry number 2198-61-0	22
Ultrasensitive electrochemical sensor for detection of rutin antioxidant by layered Ti3Al0.5Cu0.5C2 MAX phase	22
Cytotoxic and genotoxic effects of ytterbium oxide nanoparticles in human dermal fibroblasts: Accompanied by physicochemical characterization	21
Update to RIFM fragrance ingredient safety assessment, dimethyl succinate, CAS Registry Number 106-65-0	21
Risk assessment of potentially toxic trace elements via consumption of dairy products sold in the city of Yerevan, Armenia	21
Probabilistic human health risk assessment of toxic elements in rice grains from industrially and non-industrially impacted areas of Bangladesh	21
Vallaris solanacea induces mitochondrial mediated apoptosis in HL-60 human promyelocytic leukemia cells	21
Choice of experimental model determines translational impact: The link between bisphenol A and cardiotoxicity	21
RIFM fragrance ingredient safety assessment, benzoic acid, 2-hydroxy-5-methyl-, methyl ester, CAS Registry Number 22717-57-3	21
Editorial Board	21
Protective role of the dried white mulberry extract on the reproductive damage and fertility in rats treated with carmustine	21
Investigation of eight cellulose nanomaterials’ impact on Differentiated Caco-2 monolayer integrity and cytotoxicity	21
RIFM fragrance ingredient safety assessment, 4-thujanol, CAS Registry Number 546-79-2	21
Tri-ortho-cresyl phosphate causes glucose intolerance and insulin resistance in mice by inducing oxidative stress	21
Mechanisms of PDC-induced testicular Toxicity: Oxidative stress, steroidogenic suppression, and modulation by ZnO-NP/TEO synergy	21
Metabolic effects of chronic exposure to environmentally relevant concentrations of N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) in mice during diet-induced obesity progression	21
Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived	20
Review of the oral toxicity of cannabidiol (CBD)	20
Editorial Board	20
An in vitro protocol to characterise the resistance of food proteins to intestinal digestion	20
A time-course study of microglial activation and dopaminergic neuron loss in the substantia nigra of mice with paraquat-induced Parkinson's disease	20
Editorial Board	20
Atrazine-induced oxidative damage via modulating xenobiotic-sensing nuclear receptors and cytochrome P450 systems in cerebrum and antagonism of lycopene	20
Update to RIFM fragrance ingredient safety assessment, 2-ethyl-5-methoxybicyclo[2.2.1]heptane, CAS registry number 122795-41-9	20
Sub-acute administration of metal-organic Framework-5 induces behavioral impairments and augments the levels of oxidative stress and inflammation in the brain of rats	20
Bisphenol S exposure induces intestinal inflammation via altering gut microbiome	20
Dietary exposure to mixtures of chemicals in the first year of life and allergic and respiratory diseases up to 8 years in the French EDEN mother-child cohort	20
Update to RIFM fragrance ingredient safety assessment, methyl 2-octynoate, CAS Registry Number 111-12-6	20
Lysosomal dependent transcytosis of polystyrene nanoplastics within macrophages	20
Pharmacokinetics and 28-day repeated-dose toxicity of enniatin B after oral administration in mice	20
Perfluorooctanoic acid affects in vitro adipogenesis in murine preadipocytes acting as an inducer of hypertrophic adipocytes	20
PAK1 mediates ivermectin-induced DNA damage in porcine oocytes during meiotic maturation	20
Mitochondrial damage precedes the changes of glutathione metabolism in CdCl2 treated neuronal SH-SY5Y cells	20
Genetic variations of CYP3A4 on the metabolism of itraconazole in vitro	20
Update to RIFM fragrance ingredient safety assessment, isobutyl acetate, CAS Registry Number 110-19-0	20
Enantioselective toxicity effect and mechanism of hexaconazole enantiomers to human breast cancer cells	20
Exploring the cytoprotective potential of Sideritis congesta extracts in APAP-induced hepatotoxicity: in vitro and in silico approaches	20
The Austrian children's biomonitoring survey 2020 Part B: Mycotoxins, phytotoxins, phytoestrogens and food processing contaminants	20
Potential underlying mechanisms of ethambutol induced optic neuropathy: Evidence from in vitro to clinical studies	20
RIFM fragrance ingredient safety assessment, sclareolide, CAS Registry Number 564-20-5	20
Perfluorohexane sulfonate (PFHxS) induces liver cytotoxicity by activating autophagy and endoplasmic reticulum stress-regulated mitochondrial pathway apoptosis	20
Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs	19
Quantification and risk assessment of pesticide residues in Sultani seedless grapes: Implications for consumer safety	19
Use of transcriptomics in hazard identification and next generation risk assessment: A case study with clothianidin	19
Update to RIFM fragrance ingredient safety assessment, hydroxycitronellal dimethyl acetal, CAS Registry number 141-92-4	19
Update to RIFM fragrance ingredient safety assessment, p-isopropylacetophenone, CAS Registry Number 645-13-6	19