Food and Chemical Toxicology

Papers
(The TQCC of Food and Chemical Toxicology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
RIFM fragrance ingredient safety assessment, acetaldehyde ethyl cis-3-hexenyl acetal, CAS Registry Number 28069-74-1330
Update to RIFM fragrance ingredient safety assessment, 3-methylbutanal diethyl acetal, CAS Registry Number 3842-03-3248
Editorial Board205
Investigation and evaluation of gastrointestinal toxicity biomarkers in rats with different sites of gastrointestinal injury153
Editorial Board139
Assessing the toxic dose of the potent antioxidant 3,5-dihydroxy-4-methoxybenzyl alcohol in rats123
Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway122
Inhibition of human sulfotransferases (SULTs) by per- and polyfluoroalkyl substances (PFASs) and structure-activity relationship114
Predicting chemicals’ toxicity pathway of female reproductive disorders using AOP7 and deep neural networks104
No-observed adverse effect levels of deoxynivalenol and aflatoxin B1 in combination induced immune inhibition and apoptosis in vivo and in vitro99
Preclinical toxicity evaluation of the novel anti-hypertensive compound KSD17901995
The “steric-like” inhibitory effect and mechanism of doxycycline on florfenicol metabolism: Interaction risk93
Kidney toxicity and transcriptome analyses of male ICR mice acutely exposed to the mushroom toxin α-amanitin79
Update to RIFM fragrance ingredient safety assessment, 3-tert-butylcyclohexyl acetate, CAS Registry Number 31846-06-774
RIFM natural complex substance (NCS) fragrance ingredient safety assessment, lavandin abrialis, CAS registry number 8022-15-9, RIFM ID 104855473
Identification of non-volatile non-intentionally added substances from polyester food contact coatings and genotoxicity assessment of polyester coating's migrates73
Substance depletion of monoterpenes in the mouse lymphoma assay: Quantification, impact and mitigation73
Update to RIFM fragrance ingredient safety assessment, octyl butyrate, CAS Registry Number 110-39-471
RIFM fragrance ingredient safety assessment, furfural, CAS Registry Number 98-01-170
RIFM fragrance ingredient safety assessment, 2-methylpropyl 2-methylbutyrate, CAS Registry Number 2445-67-264
RIFM fragrance ingredient safety assessment, ethyl 2-ethylhexanoate, CAS Registry Number 2983-37-162
Update to RIFM fragrance ingredient safety assessment, 1-naphthalenol, 1,2,3,4,4a,5,8,8a-octahydro-2,2,6,8-tetramethyl-, CAS Registry Number 103614-86-460
RIFM fragrance ingredient safety assessment, bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-, benzoate, CAS Registry Number 55066-54-160
Update to RIFM fragrance ingredient safety assessment, 2H-inden-2-one, 1,3-dihydro-, CAS Registry Number 615-13-458
RIFM fragrance ingredient safety assessment, ethyl valerate, CAS Registry Number 539-82-258
Update to RIFM fragrance ingredient safety assessment, 4-methylpentanoic acid, CAS Registry Number 646-07-157
RIFM fragrance ingredient safety assessment, 3-buten-2-one, 4-(2,2,3-trimethyl-6-methylenecyclohexyl)-, CAS registry number 79-68-556
Update to RIFM fragrance ingredient safety assessment, pentyl benzoate, CAS Registry Number 2049-96-956
RIFM fragrance ingredient safety assessment, styrene, CAS Registry Number 100-42-555
Editorial Board54
RIFM fragrance ingredient safety assessment, 2-pentylcyclopentan-1-ol, CAS Registry Number 84560-00-953
RIFM fragrance ingredient safety assessment, isopentyl 2-methylcrotonate (E), CAS Registry Number 41519-18-052
RIFM fragrance ingredient safety assessment, 2-acetyl-3-methylpyrazine, CAS Registry number 23787-80-651
Update to RIFM fragrance ingredient safety assessment, hexyl isovalerate, CAS Registry Number 10032-13-050
RIFM fragrance ingredient safety assessment, methyl butyrate, CAS registry number 623-42-750
RIFM fragrance ingredient safety assessment, ethyl decanoate, CAS Registry Number 110-38-349
Lithium suppresses the Ras-Raf-MEK-ERK signaling in CD4 T cells and impairs the humoral immune system49
RIFM fragrance ingredient safety assessment, isoeugenyl methyl ether, CAS Registry Number 93-16-349
Farnesol prevents chlorpyrifos nephrotoxicity by modulating inflammatory mediators, Nrf2 and FXR and attenuating oxidative stress48
Exploring time dependent trends and risks of pyrrolizidine alkaloids and their N-oxides in food48
Global review, meta-analysis and health risk assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in chicken kebab using Monte Carlo simulation method46
Sustained high expression of NRF2 inhibits cell apoptosis in arsenite-transformed human keratinocytes46
Inhalation toxicity of thermal transformation products formed from e-cigarette vehicle liquid using an in vitro lung model exposed at the Air–Liquid Interface46
Comparative detection of E. coli, B. subtilis and their mixture in yam samples by ATP bioluminescence and SERS methods45
Combined environmental relevant exposure to perfluorooctanoic acid and zinc sulfate enhances apoptosis through binding with endogenous antioxidants in Daphnia magna45
Ultra-fast liquid chromatography detection of β-N-methylamine-l-alanine and its isomers in cycad seeds and cyanobacterial symbionts for neurotoxic risk assessment44
Gene expression profiles related to apoptosis and levels of DNA oxidative damage in primary dermal fibroblast cells (ATCC® PCS-201-012TM) treated with zirconium oxide nanoparticles44
NRF-2α and mitophagy underlie enhanced mitochondrial functions and biogenesis induced by T-2 toxin in GH3 cells44
Microcystin-LR exposure interfered maintenance of colonic microenvironmental homeostasis in rat44
RIFM fragrance ingredient safety assessment, α-hexylcinnamaldehyde, CAS Registry Number 101-86-044
Cardiac oxylipin perturbances in response to 2-monochloropropane-1,3-diol exposure are ameliorated by dietary adequacy of the essential n-3 fatty acid, α-linolenic acid44
Low-dose benzo[a]pyrene exposure induces hepatic lipid deposition through LCMT1/PP2Ac-mediated autophagy inhibition43
Gallic, ellagic acids and their oral combined administration induce kidney, lung, and heart injury after acute exposure in Wistar rats43
Theaflavin alleviates cisplatin-induced nephrotoxicity: Targeting SIRT1/p53/FOXO3a/Nrf2 signaling and the NF-kB inflammatory cascade43
Probiotic lactobacilli attenuate oxysterols-induced alteration of intestinal epithelial cell monolayer permeability: Focus on tight junction modulation43
Sinomenine synergistically enhances 5-Fu anticancer effects in oral cancer through modulating the miR-140-5p-PDK1-anaerobic glycolysis pathway42
The role of GSK3β signaling mediated lysosomal biosynthesis dysregulation in fluoride-induced neurological impairment42
From food-to-human microplastics and nanoplastics exposure and health effects: A review on food, animal and human monitoring data41
Tectorigenin ameliorated high-fat diet-induced nonalcoholic fatty liver disease through anti-inflammation and modulating gut microbiota in mice41
Functional evaluation of fibroblast-to-myofibroblast transition as an in vitro screening tool for pulmonary fibrosis41
Toxicity assessment of heavy metals translocation in maize grown in the Ganges delta floodplain soils around the Payra power plant in Bangladesh41
Acrylamide in food: Occurrence, metabolism, molecular toxicity mechanism and detoxification by phytochemicals41
Preclinical safety evaluation of sodium l-methylfolate40
Health risks associated with the consumption of shrimp and squid contaminated with heavy metals in Poland40
Integrated approaches to testing and assessment for the endocrine disrupting activity of tartrazine based on adverse outcome pathways and OECD frameworks40
Gut-gonad crosstalk in mice exposed to a “chemical cocktail” combining metabolomics and microbial profile by amplicon sequencing39
Assessment of human health risk concerning edible plants contamination with toxic elements around functional and derelict mines39
Curcumin mitigates gentamicin induced-renal and cardiac toxicity via modulation of Keap1/Nrf2, NF-κB/iNOS and Bcl-2/BAX pathways39
Rutin, a natural flavonoid glycoside, ameliorates zearalenone induced liver inflammation via inhibiting lipopolysaccharide gut leakage and NF-κB signaling pathway in mice39
MiR-93 alleviates DEHP plasticizer-induced neurotoxicity by negatively regulating TNFAIP1 and inhibiting ubiquitin-mediated degradation of CK2β38
Bisphenol A and its analogue bisphenol S exposure reduce estradiol synthesis via the ROS-mediated PERK/ATF4 signaling pathway38
EGCG exposure during pregnancy affects uterine histomorphology in F1 female mice and the underlying mechanisms38
Analyzing differences in gut microbiota in secondary failure of sulfonylureas through 16S rDNA sequencing and metabolomics38
Diisobutyl phthalate (DiBP)-induced male germ cell toxicity and its alleviation approach38
Evaluation of cigarette smoke-induced oxidative stress and inflammation in BEAS-2B cells based on a lung microfluidic chip38
In response to the Letter to the Editor from Xiao regarding our article, “FEMA GRAS assessment of natural flavor complexes: Asafetida oil, garlic oil and onion oil”37
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice37
RIFM fragrance ingredient safety assessment, acetylcarene, CAS Registry Number 3608-11-537
Mitigating Bisphenol-Induced Neurotoxicity: Exploring the Therapeutic Potential of Diosmin in Zebrafish Larvae36
Liensinine, a alkaloid from lotus plumule, mitigates lipopolysaccharide-induced sepsis-associated encephalopathy through modulation of nuclear factor erythroid 2-related factor-mediated inflammatory b36
N-(2-ozoazepan-3-yl)-pyrrolidine-2-carboxamide, a novel Octopus vulgaris ink-derived metabolite, exhibits a pro-apoptotic effect on A549 cancer cell line and inhibits pro-inflammatory markers36
Alcohol induces hepatocytes necroptosis through the LC3/RIPK1/RIPK3 pathway36
Experimental evaluation of favipiravir (T-705)-induced liver and kidney toxicity in rats36
Characterizing the risk related to the exposure to methylmercury over a lifetime: A global approach using population internal exposure36
Organophosphate esters and their metabolites in Beijing total diets: Occurrence, time trend, and dietary exposure assessment36
Melatonin protects against diclofenac induced oxidative stress mediated myocardial toxicity in rats: A mechanistic insight36
Epigallocatechin gallate-rich fraction alleviates histamine-induced neurotoxicity in rats via inactivating caspase-3/JNK signaling pathways35
RIFM fragrance ingredient safety assessment, p-isopropyl phenylacetaldehyde, CAS Registry Number 4395-92-035
Update to RIFM fragrance ingredient safety assessment, nonyl acetate, CAS registry number 143-13-535
RIFM fragrance ingredient safety assessment, cycloionone, CAS Registry Number 5552-30-735
RIFM fragrance ingredient safety assessment, 2,4,4,7-tetramethylnona-6,8-diene-3-one-oxime, CAS Registry Number 81783-01-935
Update to RIFM fragrance ingredient safety assessment, linalyl acetate, CAS registry number 115-95-734
RIFM fragrance ingredient safety assessment, dodecahydro-3,8,8,11a-tetramethyl-5H-3,5a-epoxynaphth[2,1-c]oxepin, CAS Registry Number 57345-19-434
Update to RIFM fragrance ingredient safety assessment, p-tolyl alcohol, CAS Registry Number 589-18-434
RIFM fragrance ingredient safety assessment, germacrene D, CAS Registry Number 23986-74-534
Update to RIFM fragrance ingredient safety assessment, methyl benzoate, CAS Registry Number 93-58-334
RIFM fragrance ingredient safety assessment, 3-(p-isopropylphenyl)propionaldehyde, CAS registry number 7775-00-033
RIFM fragrance ingredient safety assessment, cis- and trans-p-1(7),8-menthadien-2-yl acetate, CAS registry number 71660-03-233
RIFM fragrance ingredient safety assessment, ω-6-hexadecenlactone, CAS Registry Number 7779-50-232
RIFM fragrance ingredient safety assessment, 3-phenyl-3-buten-1-yl acetate, CAS Registry Number 7306-12-932
RIFM fragrance ingredient safety assessment, o-methoxybenzaldehyde, CAS Registry Number 135-02-432
RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, tangelo oil, expressed, CAS Registry Number 72869-73-9, RIFM ID 931-G2.532
RIFM fragrance ingredient safety assessment, patchouli alcohol, CAS Registry Number 5986-55-032
Update to RIFM fragrance ingredient safety assessment, methyl phenylacetate, CAS Registry Number 101-41-732
Rapid identification of counterfeited beef using deep learning-aided spectroscopy: Detecting colourant and curing agent adulteration31
Hyperoside attenuates Cd-induced kidney injury via inhibiting NLRP3 inflammasome activation and ROS/MAPK/NF-κB signaling pathway in vivo and in vitro31
Active compounds of licorice ameliorate microplastics-induced intestinal damage by targeting FADD31
Update to RIFM fragrance ingredient safety assessment, ethyl benzoate, CAS Registry Number 93-89-031
Chlorinated organophosphorus flame retardants-induced mitochondrial abnormalities and the correlation with progesterone production in mLTC-1 cells31
Update to RIFM fragrance ingredient safety assessment, menthyl acetate (isomer unspecified), CAS registry number 16409-45-331
RIFM fragrance ingredient safety assessment, 4-acetoxy-2,5-dimethyl-3(2H)furanone, CAS Registry Number 4166-20-531
Exploring the link between PFASs exposure and gestational diabetes risk within the TRAEC framework31
RIFM fragrance ingredient safety assessment, cedryl formate, CAS Registry Number 39900-38-431
RIFM fragrance ingredient safety assessment, (1aα,4α,7aα)-1a,3,3,4,6,6-hexamethyl-1a,2,3,4,5,6,7,7a-octahydronapth[3,3-b]oxirene, CAS Registry Number 94400-98-330
RIFM fragrance ingredient safety assessment, benzoic acid, 2-[[3-(4-methoxyphenyl)-2-methylpropylidene]amino]-, methyl ester, CAS registry number 111753-62-930
Toxicology of Dyes: Editorial Introduction30
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro29
Multivariate analysis of potentially toxic metal contents in soil and vegetables: Enrichment, bioconcentration, translocation from soil to vegetables, and assessment of human health toxicity29
CDKN1A promotes Cis-induced AKI by inducing cytoplasmic ROS production and ferroptosis29
Update to RIFM fragrance ingredient safety assessment, isobutyl propionate, CAS Registry Number 540-42-129
Bisphenol a exposure decreases learning ability through the suppression of mitochondrial oxidative phosphorylation in the hippocampus of male mice29
Determination of acrylamide levels in chips/crisps on the Italian market and exposure risk assessment29
Chronic exposure to B[a]P induces malignant transformation of breast epithelial cells through the mechanism via TGF-β signaling pathway29
Enniatin B and beauvericin affect intestinal cell function and hematological processes in Atlantic salmon (Salmo salar) after acute exposure29
Kaempferol improves recurrent spontaneous abortion outcomes and prevents oxidative stress damage by inhibiting the NF-kB signaling pathway29
RIFM fragrance ingredient safety assessment, 3-mercaptohexyl acetate, CAS Registry Number 136954-20-629
Non-allergenic mixed T cell epitope peptides for preventing Scy p 9 allergic reactions29
RIFM fragrance ingredient safety assessment, sssmenthadiene-7-methyl formate, CAS registry number 68683-20-528
RIFM fragrance ingredient safety assessment, phenethyl propionate, CAS Registry Number 122-70-328
RIFM fragrance ingredient safety assessment, 2-phenylhexanenitrile, CAS registry number 3508-98-328
Editorial Board28
RIFM fragrance ingredient safety assessment, 1-formyl-1-methyl-4-(4-methyl-pentyl)-3-cyclohexene, CAS Registry Number 66327-54-628
Update to RIFM fragrance ingredient safety assessment, α,2,2,3-tetramethylcyclopent-3-ene-1-butyraldehyde, CAS Registry Number 65114-03-628
RIFM fragrance ingredient safety assessment, benzene, 1-(dimethoxymethyl)-4-methoxy-, CAS Registry Number 2186-92-728
RIFM fragrance ingredient safety assessment, oxacyclopentadec-10-en-2-one, 13-methyl-, CAS Registry Number 329925-33-928
RIFM fragrance ingredient safety assessment, ethyl butyrate, CAS registry number 105-54-427
RIFM fragrance ingredient safety assessment, d,l-menthone 1,2-glycerol ketal, CAS Registry Number 63187-91-727
Beyond monitoring: Integrating risk, benefit, and biomonitoring in Greek dietary exposure to dioxins and PCBs27
RIFM fragrance ingredient safety assessment, 1,1-dimethyl-2-phenylethyl acetate, CAS registry number 151-05-327
Integrated network toxicology and transcriptomics analysis reveals the pathogenic mechanisms in DBP/MBP-induced MASLD/MASH27
Unravelling the anti-inflammatory and antioxidant effects of standardized green and black caffeinated coffee, tea, and their mixtures in an obese male rat model: Insights from biochemical, metabolomic27
Update to RIFM fragrance ingredient safety assessment, trans-2-hexenoic acid, CAS Registry Number 13419-69-727
Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan27
Apigenin in cancer therapy: From mechanism of action to nano-therapeutic agent26
Probiotic cultures as a potential protective strategy against the toxicity of environmentally relevant chemicals: State-of-the-art knowledge26
Isochlorogenic acid A ameliorated lead-induced anxiety-like behaviors in mice by inhibiting ferroptosis-mediated neuroinflammation via the BDNF/Nrf2/GPX4 pathways26
Chemical Exposure and Hepatic Steatosis: How Environmental Factors Impact Liver Health26
Emamectin benzoate-induced toxicity affects intestinal epithelial integrity involving apoptosis26
Corrigendum to “Effects of gelatin-based antifreeze peptides on cell viability and oxidant stress of Streptococcus thermophilus during cold stage” [Food Chem. Toxicol. 136 (2020) 111056]25
Environmental toxicity risk evaluation of nitroaromatic compounds: Machine learning driven binary/multiple classification and design of safe alternatives25
Association between Di-2-ethylhexyl phthalate and nonalcoholic fatty liver disease among US adults: Mediation analysis of body mass index and waist circumference in the NHANES25
New insights into mechanisms of valproic acid-induced neurodevelopmental toxicity in autism spectrum disorder: An integrative network toxicology approach combined with in vivo validation25
Piceatannol upregulates USP14-mediated GPX4 deubiquitination to inhibit neuronal ferroptosis caused by cerebral ischemia-reperfusion in mice25
Corrigendum to “Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway” [Food and Chemical Toxico25
Fertility-enhancing effects of inositol & vitamin C on cisplatin induced ovarian and uterine toxicity in rats via suppressing oxidative stress and apoptosis25
Deoxynivalenol upregulates hypoxia-inducible factor-1α to promote an “immune evasion” process by activating STAT3 signaling25
In silico and in vitro safety assessment of a fungal biomass from Rhizomucor pusillus for use as a novel food ingredient25
Glyphosate and AMPA-induced apoptosis and epigenetic alterations in HepG2 Cells: Upregulation of p53-BAX-CASP pathways25
Mycotoxins in raw materials, beverages and supplements of botanicals: A review of occurrence, risk assessment and analytical methodologies25
Hyoscyamine induces developmental toxicity by disrupting metabolism in zebrafish embryo (Danio rerio)25
Update to RIFM fragrance ingredient safety assessment, 3-methyl-2-butenyl acetate, CAS Registry Number 1191-16-825
Development and application of an interactive generic physiologically based pharmacokinetic (igPBPK) model for adult beef cattle and lactating dairy cows to estimate tissue distribution and edible tis24
RIFM fragrance ingredient safety assessment, 1-propanol, 2-methyl-3-[(1,7,7-trimethylbicyclo-[2.2.1]hept-2-yl)oxy]-, CAS Registry Number 128119-70-024
RIFM fragrance ingredient safety assessment, pyridine, 4-[1(4-,5 or 6)-methylbicyclo[2.2.1]hept-5-en-2-yl]-, CAS Registry Number 862079-91-224
Triptolide exposure triggers ovarian inflammation by activating cGAS-STING pathway and decrease oocyte quality in mouse24
Update to RIFM fragrance ingredient safety assessment, benzyl formate, CAS Registry Number 104-57-424
Update to RIFM fragrance ingredient safety assessment, acetaldehyde, diphenethyl acetal, CAS Registry Number 122-71-424
RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]deca-3,6-diene, 2,6,9,10-tetramethyl-, CAS Registry Number 71078-31-424
Impact of food matrices on the characteristics and cellular toxicities of ingested nanoplastics in a simulated digestive tract24
Acute ivermectin toxicity on skin and brain tissue of adult albino rats: Evaluation of the role of Flumazenil and Vitamin C as new treatment modalities24
RIFM fragrance ingredient safety assessment, butyl salicylate, CAS Registry Number 2052-14-424
RIFM fragrance ingredient safety assessment, 3,3,5-trimethylcyclohexyl ethyl ether, CAS Registry Number 67583-77-123
Update to RIFM fragrance ingredient safety assessment, isoamyl hexanoate, CAS registry number 2198-61-023
RIFM fragrance ingredient safety assessment, 2,3,5-trimethylpyrazine, CAS registry number 14667-55-123
Editorial Board23
Choice of experimental model determines translational impact: The link between bisphenol A and cardiotoxicity23
Update to RIFM fragrance ingredient safety assessment, dimethyl succinate, CAS Registry Number 106-65-023
RIFM fragrance ingredient safety assessment, 11-oxahexadecanolide, CAS Registry Number 3391-83-123
RIFM fragrance ingredient safety assessment, 4-thujanol, CAS Registry Number 546-79-223
RIFM fragrance ingredient safety assessment, thymol, CAS Registry Number 89-83-823
Pharmacokinetics and 28-day repeated-dose toxicity of enniatin B after oral administration in mice23
RIFM fragrance ingredient safety assessment, 3-hexanone, 5-mercapto-5-methyl-, CAS Registry Number 851768-51-923
RIFM fragrance ingredient safety assessment, methyl sorbate, CAS Registry Number 689-89-423
Update to RIFM fragrance ingredient safety assessment, hexanoic acid, 4-methyl-, CAS registry number 1561-11-123
RIFM fragrance ingredient safety assessment, methyl p-methylbenzoate, CAS Registry Number 99-75-223
Potential exacerbation of polycystic ovary syndrome by saccharin sodium Via taste receptors in a letrozole rat model23
Editorial Board22
Metabolic effects of chronic exposure to environmentally relevant concentrations of N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) in mice during diet-induced obesity progression22
RIFM fragrance ingredient safety assessment, d-8-p-menthene-1,2-epoxide, CAS Registry Number 1195-92-222
Neurotoxicity of dibutyl phthalate in zebrafish larvae: Decreased energy acquisition by neurons22
RIFM fragrance ingredient safety assessment, isolongifolene oxide, CAS Registry Number 26619-69-222
Investigation of eight cellulose nanomaterials’ impact on Differentiated Caco-2 monolayer integrity and cytotoxicity22
Mitochondrial damage precedes the changes of glutathione metabolism in CdCl2 treated neuronal SH-SY5Y cells22
Update to RIFM fragrance ingredient safety assessment, β-caryophyllene alcohol, CAS registry number 472-97-921
Tri-ortho-cresyl phosphate causes glucose intolerance and insulin resistance in mice by inducing oxidative stress21
Probabilistic human health risk assessment of toxic elements in rice grains from industrially and non-industrially impacted areas of Bangladesh21
Update to RIFM fragrance ingredient safety assessment, 2-ethyl-5-methoxybicyclo[2.2.1]heptane, CAS registry number 122795-41-921
Therapeutic potential of 2S-hesperidin against the hepatotoxic effects of dichlorvos in rats21
Fluquinconazole disrupts calcium and mitochondrial homeostasis, leading to bovine mammary epithelial cell death21
Bioactive extract of Morchella esculenta ameliorates cyclophosphamide-induced mitochondrial dysfunction and cardiotoxicity by modulating KEAP1/NRF2 and pro-inflammatory genes expression21
Cytotoxic and genotoxic effects of ytterbium oxide nanoparticles in human dermal fibroblasts: Accompanied by physicochemical characterization21
PAK1 mediates ivermectin-induced DNA damage in porcine oocytes during meiotic maturation21
Atrazine-induced oxidative damage via modulating xenobiotic-sensing nuclear receptors and cytochrome P450 systems in cerebrum and antagonism of lycopene21
The toxicity of lead on human neuroblastoma cells was alleviated by HUC-MSC-derived exosomes through miR-26a-5p/PTEN pathway21
Sub-acute administration of metal-organic Framework-5 induces behavioral impairments and augments the levels of oxidative stress and inflammation in the brain of rats21
In vitro toxicological assessment of aerosols from indirectly heated tobacco products using a solvent-free extraction method21
Perfluorooctanoic acid affects in vitro adipogenesis in murine preadipocytes acting as an inducer of hypertrophic adipocytes21
Mechanisms of PDC-induced testicular Toxicity: Oxidative stress, steroidogenic suppression, and modulation by ZnO-NP/TEO synergy21
RIFM fragrance ingredient safety assessment, sclareolide, CAS Registry Number 564-20-521
Bisphenol analogues inhibit human and rat 17β-hydroxysteroid dehydrogenase 1: 3D-quantitative structure-activity relationship (3D-QSAR) and in silico docking analysis21
An in vitro protocol to characterise the resistance of food proteins to intestinal digestion20
Carcinogenic and non-carcinogenic risks caused by rice contamination with heavy metals and their effect on the prevalence of cardiovascular disease (Using machine learning)20
High fructose-induced skeletal muscle insulin resistance could be alleviated by berberine via AMPD1 and ADSL20
A time-course study of microglial activation and dopaminergic neuron loss in the substantia nigra of mice with paraquat-induced Parkinson's disease20
Ultrasensitive electrochemical sensor for detection of rutin antioxidant by layered Ti3Al0.5Cu0.5C2 MAX phase20
Exposure to short-, medium-, and long-chain chlorinated paraffins for infant via cow infant formula, goat infant formula and baby food20
The Austrian children's biomonitoring survey 2020 Part B: Mycotoxins, phytotoxins, phytoestrogens and food processing contaminants20
Genetic variations of CYP3A4 on the metabolism of itraconazole in vitro20
Dietary exposure to mixtures of chemicals in the first year of life and allergic and respiratory diseases up to 8 years in the French EDEN mother-child cohort20
Perfluorohexane sulfonate (PFHxS) induces liver cytotoxicity by activating autophagy and endoplasmic reticulum stress-regulated mitochondrial pathway apoptosis20
Vallaris solanacea induces mitochondrial mediated apoptosis in HL-60 human promyelocytic leukemia cells20
Dermal repeated dose toxicity study of the anti-breast cancer drug Formestane cream in Bama minipig20
Potential underlying mechanisms of ethambutol induced optic neuropathy: Evidence from in vitro to clinical studies20
Chronic glucocorticoid exposure accelerates Aβ generation and neurotoxicity by activating calcium-mediated CN-NFAT1 signaling in hippocampal neurons in APP/PS1 mice20
Bisphenol S exposure induces intestinal inflammation via altering gut microbiome20
Enantioselective toxicity effect and mechanism of hexaconazole enantiomers to human breast cancer cells20
Review of the oral toxicity of cannabidiol (CBD)20
Exploring the cytoprotective potential of Sideritis congesta extracts in APAP-induced hepatotoxicity: in vitro and in silico approaches20
Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived 20
Maternal exposure to a glyphosate-based herbicide impairs placental development through endoplasmic reticulum stress in mice20
Exploring a health effect sensitivity distribution method for deriving microplastic toxicity thresholds: Application to microplastic risk assessment of school-aged children in Pudong, Shanghai20
RIFM fragrance ingredient safety assessment, benzoic acid, 2-hydroxy-5-methyl-, methyl ester, CAS Registry Number 22717-57-320
Safety and toxicologic evaluation of Edible Pongamia Oil: A novel food ingredient20
Lysosomal dependent transcytosis of polystyrene nanoplastics within macrophages20
Update to RIFM fragrance ingredient safety assessment, isoeugenol, CAS registry number 97-54-119
RIFM fragrance ingredient safety assessment, ethyl acetate, CAS Registry Number 141-78-619
Update to RIFM fragrance ingredient safety assessment, p-isopropylacetophenone, CAS Registry Number 645-13-619
RIFM fragrance ingredient safety assessment, heptyl alcohol, CAS registry number 111-70-619
RIFM fragrance ingredient safety assessment, 6,10-dodecadienal, 3,7,11-trimethyl-, (3S,6E)-, CAS registry number 194934-66-219
RIFM fragrance ingredient safety assessment, nopyl acetate, CAS registry number 128-51-819
Update to RIFM fragrance ingredient safety assessment, methyl undec-10-enoate, CAS registry number 111-81-919
Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway19
Update to RIFM fragrance ingredient safety assessment, 4-isopropyl-2-methoxy-1-methylbenzene, CAS Registry Number 6379-73-319
Editorial Board19
RIFM fragrance ingredient safety assessment, cis-6-nonenal, CAS registry number 2277-19-219
Update to RIFM fragrance ingredient safety assessment, 2-methylvaleric acid, CAS Registry Number 97-61-019
RIFM fragrance ingredient safety assessment, 1-spiro[4.5]dec-7-en-7-yl-4-penten-1-one, CAS Registry Number 224031-70-319
Update to RIFM fragrance ingredient safety assessment, hydroxycitronellal dimethyl acetal, CAS Registry number 141-92-419
Update to RIFM fragrance ingredient safety assessment, linalyl phenylacetate, CAS Registry Number 7143-69-319
Update to RIFM fragrance ingredient safety assessment, l-carvone, CAS Registry Number 6485-40-119
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