Food and Chemical Toxicology

Papers
(The TQCC of Food and Chemical Toxicology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
RIFM fragrance ingredient safety assessment, acetaldehyde ethyl cis-3-hexenyl acetal, CAS Registry Number 28069-74-1221
Update to RIFM fragrance ingredient safety assessment, 3-methylbutanal diethyl acetal, CAS Registry Number 3842-03-3164
Editorial Board148
Investigation and evaluation of gastrointestinal toxicity biomarkers in rats with different sites of gastrointestinal injury125
Editorial Board99
Assessing the toxic dose of the potent antioxidant 3,5-dihydroxy-4-methoxybenzyl alcohol in rats83
Inhibition of human sulfotransferases (SULTs) by per- and polyfluoroalkyl substances (PFASs) and structure-activity relationship78
Predicting chemicals’ toxicity pathway of female reproductive disorders using AOP7 and deep neural networks74
No-observed adverse effect levels of deoxynivalenol and aflatoxin B1 in combination induced immune inhibition and apoptosis in vivo and in vitro72
The “steric-like” inhibitory effect and mechanism of doxycycline on florfenicol metabolism: Interaction risk68
Update to RIFM fragrance ingredient safety assessment, 3-tert-butylcyclohexyl acetate, CAS Registry Number 31846-06-766
RIFM natural complex substance (NCS) fragrance ingredient safety assessment, lavandin abrialis, CAS registry number 8022-15-9, RIFM ID 104855463
Substance depletion of monoterpenes in the mouse lymphoma assay: Quantification, impact and mitigation61
Update to RIFM fragrance ingredient safety assessment, octyl butyrate, CAS Registry Number 110-39-458
RIFM fragrance ingredient safety assessment, 2-methylpropyl 2-methylbutyrate, CAS Registry Number 2445-67-257
Update to RIFM fragrance ingredient safety assessment, 1-naphthalenol, 1,2,3,4,4a,5,8,8a-octahydro-2,2,6,8-tetramethyl-, CAS Registry Number 103614-86-456
RIFM fragrance ingredient safety assessment, ethyl 2-ethylhexanoate, CAS Registry Number 2983-37-156
RIFM fragrance ingredient safety assessment, bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-, benzoate, CAS Registry Number 55066-54-156
Update to RIFM fragrance ingredient safety assessment, 2H-inden-2-one, 1,3-dihydro-, CAS Registry Number 615-13-455
RIFM fragrance ingredient safety assessment, ethyl valerate, CAS Registry Number 539-82-255
Update to RIFM fragrance ingredient safety assessment, 4-methylpentanoic acid, CAS Registry Number 646-07-152
Update to RIFM fragrance ingredient safety assessment, pentyl benzoate, CAS Registry Number 2049-96-950
RIFM fragrance ingredient safety assessment, 3-buten-2-one, 4-(2,2,3-trimethyl-6-methylenecyclohexyl)-, CAS registry number 79-68-550
Editorial Board49
RIFM fragrance ingredient safety assessment, 2-pentylcyclopentan-1-ol, CAS Registry Number 84560-00-948
RIFM fragrance ingredient safety assessment, methyl butyrate, CAS registry number 623-42-746
RIFM fragrance ingredient safety assessment, 2-acetyl-3-methylpyrazine, CAS Registry number 23787-80-646
RIFM fragrance ingredient safety assessment, isoeugenyl methyl ether, CAS Registry Number 93-16-346
RIFM fragrance ingredient safety assessment, isopentyl 2-methylcrotonate (E), CAS Registry Number 41519-18-046
Lithium suppresses the Ras-Raf-MEK-ERK signaling in CD4 T cells and impairs the humoral immune system45
RIFM fragrance ingredient safety assessment, ethyl decanoate, CAS Registry Number 110-38-345
Farnesol prevents chlorpyrifos nephrotoxicity by modulating inflammatory mediators, Nrf2 and FXR and attenuating oxidative stress45
Exploring time dependent trends and risks of pyrrolizidine alkaloids and their N-oxides in food45
Assessment of human health risk concerning edible plants contamination with toxic elements around functional and derelict mines44
Functional evaluation of fibroblast-to-myofibroblast transition as an in vitro screening tool for pulmonary fibrosis44
Comparative detection of E. coli, B. subtilis and their mixture in yam samples by ATP bioluminescence and SERS methods44
Integrated approaches to testing and assessment for the endocrine disrupting activity of tartrazine based on adverse outcome pathways and OECD frameworks44
Combined environmental relevant exposure to perfluorooctanoic acid and zinc sulfate enhances apoptosis through binding with endogenous antioxidants in Daphnia magna44
Health risks associated with the consumption of shrimp and squid contaminated with heavy metals in Poland44
RIFM fragrance ingredient safety assessment, α-hexylcinnamaldehyde, CAS Registry Number 101-86-043
Cardiac oxylipin perturbances in response to 2-monochloropropane-1,3-diol exposure are ameliorated by dietary adequacy of the essential n-3 fatty acid, α-linolenic acid43
RIFM fragrance ingredient safety assessments, ethyl ricinoleate, CAS Registry Number 55066-53-042
Microcystin-LR exposure interfered maintenance of colonic microenvironmental homeostasis in rat42
Ultra-fast liquid chromatography detection of β-N-methylamine-l-alanine and its isomers in cycad seeds and cyanobacterial symbionts for neurotoxic risk assessment42
The role of GSK3β signaling mediated lysosomal biosynthesis dysregulation in fluoride-induced neurological impairment42
NRF-2α and mitophagy underlie enhanced mitochondrial functions and biogenesis induced by T-2 toxin in GH3 cells42
RIFM fragrance ingredient safety assessment, heneicosane, CAS Registry Number 629-94-742
Gallic, ellagic acids and their oral combined administration induce kidney, lung, and heart injury after acute exposure in Wistar rats42
Identification of non-volatile non-intentionally added substances from polyester food contact coatings and genotoxicity assessment of polyester coating's migrates41
EGCG exposure during pregnancy affects uterine histomorphology in F1 female mice and the underlying mechanisms41
Sinomenine synergistically enhances 5-Fu anticancer effects in oral cancer through modulating the miR-140-5p-PDK1-anaerobic glycolysis pathway41
Toxicity assessment of heavy metals translocation in maize grown in the Ganges delta floodplain soils around the Payra power plant in Bangladesh40
Diisobutyl phthalate (DiBP)-induced male germ cell toxicity and its alleviation approach40
Inhalation toxicity of thermal transformation products formed from e-cigarette vehicle liquid using an in vitro lung model exposed at the Air–Liquid Interface40
MiR-93 alleviates DEHP plasticizer-induced neurotoxicity by negatively regulating TNFAIP1 and inhibiting ubiquitin-mediated degradation of CK2β40
Maternal flutamide exposure induces spermatogenic dysfunction in male offspring: The mechanistic role of RARα-Mediated NLRP3 inflammasome activation39
TLR4 knockout ameliorates acute LPS-sensitized tolvaptan-induced idiosyncratic liver injury by disrupting drug metabolism, inflammation, and bile acid homeostasis39
Time-dependent post-exposure self-recovery rescues arsenic-induced behavioral and biochemical alterations in mice39
Gut-gonad crosstalk in mice exposed to a “chemical cocktail” combining metabolomics and microbial profile by amplicon sequencing38
Global review, meta-analysis and health risk assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in chicken kebab using Monte Carlo simulation method38
Gene expression profiles related to apoptosis and levels of DNA oxidative damage in primary dermal fibroblast cells (ATCC® PCS-201-012TM) treated with zirconium oxide nanoparticles38
Sustained high expression of NRF2 inhibits cell apoptosis in arsenite-transformed human keratinocytes38
RIFM fragrance ingredient safety assessment, furfural, CAS Registry Number 98-01-138
Theaflavin alleviates cisplatin-induced nephrotoxicity: Targeting SIRT1/p53/FOXO3a/Nrf2 signaling and the NF-kB inflammatory cascade37
Kidney toxicity and transcriptome analyses of male ICR mice acutely exposed to the mushroom toxin α-amanitin37
Low-dose benzo[a]pyrene exposure induces hepatic lipid deposition through LCMT1/PP2Ac-mediated autophagy inhibition37
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice37
Preclinical toxicity evaluation of the novel anti-hypertensive compound KSD17901937
Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway37
Curcumin mitigates gentamicin induced-renal and cardiac toxicity via modulation of Keap1/Nrf2, NF-κB/iNOS and Bcl-2/BAX pathways36
Probiotic lactobacilli attenuate oxysterols-induced alteration of intestinal epithelial cell monolayer permeability: Focus on tight junction modulation36
Toxic effects of 5-hydroxymethylfurfural on intestinal epithelial cell and its impact on the expression of MAPK pathway-related genes36
From food-to-human microplastics and nanoplastics exposure and health effects: A review on food, animal and human monitoring data36
Evaluation of cigarette smoke-induced oxidative stress and inflammation in BEAS-2B cells based on a lung microfluidic chip36
Bisphenol A and its analogue bisphenol S exposure reduce estradiol synthesis via the ROS-mediated PERK/ATF4 signaling pathway34
Preclinical safety evaluation of sodium l-methylfolate34
Acrylamide in food: Occurrence, metabolism, molecular toxicity mechanism and detoxification by phytochemicals34
In response to the Letter to the Editor from Xiao regarding our article, “FEMA GRAS assessment of natural flavor complexes: Asafetida oil, garlic oil and onion oil”33
Alcohol induces hepatocytes necroptosis through the LC3/RIPK1/RIPK3 pathway33
Rutin, a natural flavonoid glycoside, ameliorates zearalenone induced liver inflammation via inhibiting lipopolysaccharide gut leakage and NF-κB signaling pathway in mice33
Characterizing the risk related to the exposure to methylmercury over a lifetime: A global approach using population internal exposure33
N-(2-ozoazepan-3-yl)-pyrrolidine-2-carboxamide, a novel Octopus vulgaris ink-derived metabolite, exhibits a pro-apoptotic effect on A549 cancer cell line and inhibits pro-inflammatory markers33
Organophosphate esters and their metabolites in Beijing total diets: Occurrence, time trend, and dietary exposure assessment33
Update to RIFM fragrance ingredient safety assessment, nonyl acetate, CAS registry number 143-13-533
RIFM fragrance ingredient safety assessment, acetylcarene, CAS Registry Number 3608-11-533
RIFM fragrance ingredient safety assessment, p-isopropyl phenylacetaldehyde, CAS Registry Number 4395-92-032
Update to RIFM fragrance ingredient safety assessment, linalyl acetate, CAS registry number 115-95-732
Update to RIFM fragrance ingredient safety assessment, methyl benzoate, CAS Registry Number 93-58-332
RIFM fragrance ingredient safety assessment, cycloionone, CAS Registry Number 5552-30-732
RIFM fragrance ingredient safety assessment, germacrene D, CAS Registry Number 23986-74-532
Update to RIFM fragrance ingredient safety assessment, p-tolyl alcohol, CAS Registry Number 589-18-432
RIFM fragrance ingredient safety assessment, 3-(p-isopropylphenyl)propionaldehyde, CAS registry number 7775-00-032
RIFM fragrance ingredient safety assessment, 2,4,4,7-tetramethylnona-6,8-diene-3-one-oxime, CAS Registry Number 81783-01-932
RIFM fragrance ingredient safety assessment, dodecahydro-3,8,8,11a-tetramethyl-5H-3,5a-epoxynaphth[2,1-c]oxepin, CAS Registry Number 57345-19-432
RIFM fragrance ingredient safety assessment, cis- and trans-p-1(7),8-menthadien-2-yl acetate, CAS registry number 71660-03-232
Epigallocatechin gallate-rich fraction alleviates histamine-induced neurotoxicity in rats via inactivating caspase-3/JNK signaling pathways32
Update to RIFM fragrance ingredient safety assessment, methyl phenylacetate, CAS Registry Number 101-41-731
RIFM fragrance ingredient safety assessment, 3-phenyl-3-buten-1-yl acetate, CAS Registry Number 7306-12-931
RIFM fragrance ingredient safety assessment, patchouli alcohol, CAS Registry Number 5986-55-030
RIFM fragrance ingredient safety assessment, ω-6-hexadecenlactone, CAS Registry Number 7779-50-230
RIFM fragrance ingredient safety assessment, o-methoxybenzaldehyde, CAS Registry Number 135-02-430
RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, tangelo oil, expressed, CAS Registry Number 72869-73-9, RIFM ID 931-G2.530
Active compounds of licorice ameliorate microplastics-induced intestinal damage by targeting FADD29
Toxicology of Dyes: Editorial Introduction29
Exploring the link between PFASs exposure and gestational diabetes risk within the TRAEC framework29
RIFM fragrance ingredient safety assessment, 4-acetoxy-2,5-dimethyl-3(2H)furanone, CAS Registry Number 4166-20-529
Update to RIFM fragrance ingredient safety assessment, menthyl acetate (isomer unspecified), CAS registry number 16409-45-329
Update to RIFM fragrance ingredient safety assessment, ethyl benzoate, CAS Registry Number 93-89-029
RIFM fragrance ingredient safety assessment, (1aα,4α,7aα)-1a,3,3,4,6,6-hexamethyl-1a,2,3,4,5,6,7,7a-octahydronapth[3,3-b]oxirene, CAS Registry Number 94400-98-329
RIFM fragrance ingredient safety assessment, benzoic acid, 2-[[3-(4-methoxyphenyl)-2-methylpropylidene]amino]-, methyl ester, CAS registry number 111753-62-928
Enniatin B and beauvericin affect intestinal cell function and hematological processes in Atlantic salmon (Salmo salar) after acute exposure28
Unveiling the bioactive potential and chemical profiling of Oenothera glazioviana extracts: chromatographic, spectrophotometric, and in silico approaches28
Editorial Board28
Chronic exposure to B[a]P induces malignant transformation of breast epithelial cells through the mechanism via TGF-β signaling pathway28
TDCIPP induces placental dysfunction and fetal growth restriction via oxidative stress-mediated PINK1/Parkin mitophagy28
Kaempferol improves recurrent spontaneous abortion outcomes and prevents oxidative stress damage by inhibiting the NF-kB signaling pathway28
Update to RIFM fragrance ingredient safety assessment, isobutyl propionate, CAS Registry Number 540-42-128
Synergistic disruption of brain metabolism and inflammatory signaling in adult zebrafish by co-exposure to alternariol monomethyl ether and titanium dioxide nanoparticles at physiologically relevant l28
RIFM fragrance ingredient safety assessment, 3-mercaptohexyl acetate, CAS Registry Number 136954-20-628
RIFM fragrance ingredient safety assessment, d,l-menthone 1,2-glycerol ketal, CAS Registry Number 63187-91-727
Integrated network toxicology and transcriptomics analysis reveals the pathogenic mechanisms in DBP/MBP-induced MASLD/MASH27
RIFM fragrance ingredient safety assessment, benzene, 1-(dimethoxymethyl)-4-methoxy-, CAS Registry Number 2186-92-727
RIFM fragrance ingredient safety assessment, 1,1-dimethyl-2-phenylethyl acetate, CAS registry number 151-05-327
Unravelling the anti-inflammatory and antioxidant effects of standardized green and black caffeinated coffee, tea, and their mixtures in an obese male rat model: Insights from biochemical, metabolomic27
Update to RIFM fragrance ingredient safety assessment, trans-2-hexenoic acid, CAS Registry Number 13419-69-727
RIFM fragrance ingredient safety assessment, ethyl butyrate, CAS registry number 105-54-427
RIFM fragrance ingredient safety assessment, 2-phenylhexanenitrile, CAS registry number 3508-98-327
RIFM fragrance ingredient safety assessment, sssmenthadiene-7-methyl formate, CAS registry number 68683-20-527
Beyond monitoring: Integrating risk, benefit, and biomonitoring in Greek dietary exposure to dioxins and PCBs27
Emamectin benzoate-induced toxicity affects intestinal epithelial integrity involving apoptosis27
Editorial Board27
RIFM fragrance ingredient safety assessment, oxacyclopentadec-10-en-2-one, 13-methyl-, CAS Registry Number 329925-33-927
Apigenin in cancer therapy: From mechanism of action to nano-therapeutic agent26
Hyoscyamine induces developmental toxicity by disrupting metabolism in zebrafish embryo (Danio rerio)26
Probiotic cultures as a potential protective strategy against the toxicity of environmentally relevant chemicals: State-of-the-art knowledge26
New insights into mechanisms of valproic acid-induced neurodevelopmental toxicity in autism spectrum disorder: An integrative network toxicology approach combined with in vivo validation25
Update to RIFM fragrance ingredient safety assessment, 3-methyl-2-butenyl acetate, CAS Registry Number 1191-16-825
Corrigendum to “Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway” [Food and Chemical Toxico25
In silico and in vitro safety assessment of a fungal biomass from Rhizomucor pusillus for use as a novel food ingredient25
Fertility-enhancing effects of inositol & vitamin C on cisplatin induced ovarian and uterine toxicity in rats via suppressing oxidative stress and apoptosis25
Corrigendum to “Effects of gelatin-based antifreeze peptides on cell viability and oxidant stress of Streptococcus thermophilus during cold stage” [Food Chem. Toxicol. 136 (2020) 111056]25
Hyperoside attenuates Cd-induced kidney injury via inhibiting NLRP3 inflammasome activation and ROS/MAPK/NF-κB signaling pathway in vivo and in vitro25
Impact of food matrices on the characteristics and cellular toxicities of ingested nanoplastics in a simulated digestive tract24
RIFM fragrance ingredient safety assessment, cedryl formate, CAS Registry Number 39900-38-424
Non-allergenic mixed T cell epitope peptides for preventing Scy p 9 allergic reactions24
Mitigating Bisphenol-Induced Neurotoxicity: Exploring the Therapeutic Potential of Diosmin in Zebrafish Larvae24
Environmental toxicity risk evaluation of nitroaromatic compounds: Machine learning driven binary/multiple classification and design of safe alternatives24
Liensinine, a alkaloid from lotus plumule, mitigates lipopolysaccharide-induced sepsis-associated encephalopathy through modulation of nuclear factor erythroid 2-related factor-mediated inflammatory b24
Development and application of an interactive generic physiologically based pharmacokinetic (igPBPK) model for adult beef cattle and lactating dairy cows to estimate tissue distribution and edible tis24
Chlorinated organophosphorus flame retardants-induced mitochondrial abnormalities and the correlation with progesterone production in mLTC-1 cells24
Determination of acrylamide levels in chips/crisps on the Italian market and exposure risk assessment24
Multivariate analysis of potentially toxic metal contents in soil and vegetables: Enrichment, bioconcentration, translocation from soil to vegetables, and assessment of human health toxicity24
Glyphosate and AMPA-induced apoptosis and epigenetic alterations in HepG2 Cells: Upregulation of p53-BAX-CASP pathways23
RIFM fragrance ingredient safety assessment, 1-propanol, 2-methyl-3-[(1,7,7-trimethylbicyclo-[2.2.1]hept-2-yl)oxy]-, CAS Registry Number 128119-70-023
Rapid identification of counterfeited beef using deep learning-aided spectroscopy: Detecting colourant and curing agent adulteration23
CDKN1A promotes Cis-induced AKI by inducing cytoplasmic ROS production and ferroptosis23
Triptolide exposure triggers ovarian inflammation by activating cGAS-STING pathway and decrease oocyte quality in mouse23
Association between Di-2-ethylhexyl phthalate and nonalcoholic fatty liver disease among US adults: Mediation analysis of body mass index and waist circumference in the NHANES23
Update to RIFM fragrance ingredient safety assessment, benzyl formate, CAS Registry Number 104-57-423
Isochlorogenic acid A ameliorated lead-induced anxiety-like behaviors in mice by inhibiting ferroptosis-mediated neuroinflammation via the BDNF/Nrf2/GPX4 pathways23
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro23
Melatonin protects against diclofenac induced oxidative stress mediated myocardial toxicity in rats: A mechanistic insight23
Deoxynivalenol upregulates hypoxia-inducible factor-1α to promote an “immune evasion” process by activating STAT3 signaling23
Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan23
Acute ivermectin toxicity on skin and brain tissue of adult albino rats: Evaluation of the role of Flumazenil and Vitamin C as new treatment modalities23
Experimental evaluation of favipiravir (T-705)-induced liver and kidney toxicity in rats23
Piceatannol upregulates USP14-mediated GPX4 deubiquitination to inhibit neuronal ferroptosis caused by cerebral ischemia-reperfusion in mice23
Update to RIFM fragrance ingredient safety assessment, acetaldehyde, diphenethyl acetal, CAS Registry Number 122-71-423
Update to RIFM fragrance ingredient safety assessment, hexanoic acid, 4-methyl-, CAS registry number 1561-11-122
RIFM fragrance ingredient safety assessment, pyridine, 4-[1(4-,5 or 6)-methylbicyclo[2.2.1]hept-5-en-2-yl]-, CAS Registry Number 862079-91-222
Choice of experimental model determines translational impact: The link between bisphenol A and cardiotoxicity22
RIFM fragrance ingredient safety assessment, butyl salicylate, CAS Registry Number 2052-14-422
Editorial Board22
The TFAM-OGG1 axis mediates T-2 toxin-induced chondrocyte mitochondrial dysfunction and cartilage degeneration22
RIFM fragrance ingredient safety assessment, 11-oxahexadecanolide, CAS Registry Number 3391-83-122
RIFM fragrance ingredient safety assessment, methyl sorbate, CAS Registry Number 689-89-422
Update to RIFM fragrance ingredient safety assessment, isoamyl hexanoate, CAS registry number 2198-61-022
RIFM fragrance ingredient safety assessment, 2,3,5-trimethylpyrazine, CAS registry number 14667-55-122
RIFM fragrance ingredient safety assessment, 3-hexanone, 5-mercapto-5-methyl-, CAS Registry Number 851768-51-922
Pharmacokinetics and 28-day repeated-dose toxicity of enniatin B after oral administration in mice22
Maternal exposure to a glyphosate-based herbicide impairs placental development through endoplasmic reticulum stress in mice22
RIFM fragrance ingredient safety assessment, 3,3,5-trimethylcyclohexyl ethyl ether, CAS Registry Number 67583-77-122
Update to RIFM fragrance ingredient safety assessment, dimethyl succinate, CAS Registry Number 106-65-022
RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]deca-3,6-diene, 2,6,9,10-tetramethyl-, CAS Registry Number 71078-31-422
RIFM fragrance ingredient safety assessment, methyl p-methylbenzoate, CAS Registry Number 99-75-222
Lysosomal dependent transcytosis of polystyrene nanoplastics within macrophages22
PAK1 mediates ivermectin-induced DNA damage in porcine oocytes during meiotic maturation22
Update to RIFM fragrance ingredient safety assessment, 2-ethyl-5-methoxybicyclo[2.2.1]heptane, CAS registry number 122795-41-921
Therapeutic potential of 2S-hesperidin against the hepatotoxic effects of dichlorvos in rats21
Fluquinconazole disrupts calcium and mitochondrial homeostasis, leading to bovine mammary epithelial cell death21
In vitro toxicological assessment of aerosols from indirectly heated tobacco products using a solvent-free extraction method21
Metabolic effects of chronic exposure to environmentally relevant concentrations of N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) in mice during diet-induced obesity progression21
Cytotoxic and genotoxic effects of ytterbium oxide nanoparticles in human dermal fibroblasts: Accompanied by physicochemical characterization21
Investigation of eight cellulose nanomaterials’ impact on Differentiated Caco-2 monolayer integrity and cytotoxicity21
Atrazine-induced oxidative damage via modulating xenobiotic-sensing nuclear receptors and cytochrome P450 systems in cerebrum and antagonism of lycopene21
The toxicity of lead on human neuroblastoma cells was alleviated by HUC-MSC-derived exosomes through miR-26a-5p/PTEN pathway21
Probabilistic human health risk assessment of toxic elements in rice grains from industrially and non-industrially impacted areas of Bangladesh21
Bioactive extract of Morchella esculenta ameliorates cyclophosphamide-induced mitochondrial dysfunction and cardiotoxicity by modulating KEAP1/NRF2 and pro-inflammatory genes expression21
Editorial Board21
RIFM fragrance ingredient safety assessment, isolongifolene oxide, CAS Registry Number 26619-69-221
Sub-acute administration of metal-organic Framework-5 induces behavioral impairments and augments the levels of oxidative stress and inflammation in the brain of rats21
RIFM fragrance ingredient safety assessment, sclareolide, CAS Registry Number 564-20-521
Bisphenol analogues inhibit human and rat 17β-hydroxysteroid dehydrogenase 1: 3D-quantitative structure-activity relationship (3D-QSAR) and in silico docking analysis21
Tri-ortho-cresyl phosphate causes glucose intolerance and insulin resistance in mice by inducing oxidative stress21
Update to RIFM fragrance ingredient safety assessment, β-caryophyllene alcohol, CAS registry number 472-97-921
RIFM fragrance ingredient safety assessment, d-8-p-menthene-1,2-epoxide, CAS Registry Number 1195-92-221
Perfluorooctanoic acid affects in vitro adipogenesis in murine preadipocytes acting as an inducer of hypertrophic adipocytes21
Bisphenol S exposure induces intestinal inflammation via altering gut microbiome20
Potential underlying mechanisms of ethambutol induced optic neuropathy: Evidence from in vitro to clinical studies20
Safety and toxicologic evaluation of Edible Pongamia Oil: A novel food ingredient20
Normolipidic diet containing deep-fried saturated and unsaturated fatty acids rich edible oils promotes metabolic dysregulation and inflammatory microenvironment in Wistar rats20
Enantioselective toxicity effect and mechanism of hexaconazole enantiomers to human breast cancer cells20
Exploring the cytoprotective potential of Sideritis congesta extracts in APAP-induced hepatotoxicity: in vitro and in silico approaches20
Chronic glucocorticoid exposure accelerates Aβ generation and neurotoxicity by activating calcium-mediated CN-NFAT1 signaling in hippocampal neurons in APP/PS1 mice20
The Austrian children's biomonitoring survey 2020 Part B: Mycotoxins, phytotoxins, phytoestrogens and food processing contaminants20
Update to RIFM fragrance ingredient safety assessment, acetyl cedrene, CAS Registry Number 32388-55-920
Carcinogenic and non-carcinogenic risks caused by rice contamination with heavy metals and their effect on the prevalence of cardiovascular disease (Using machine learning)20
Genetic variations of CYP3A4 on the metabolism of itraconazole in vitro20
Mechanisms of PDC-induced testicular Toxicity: Oxidative stress, steroidogenic suppression, and modulation by ZnO-NP/TEO synergy20
RIFM fragrance ingredient safety assessment, benzoic acid, 2-hydroxy-5-methyl-, methyl ester, CAS Registry Number 22717-57-320
Exploring a health effect sensitivity distribution method for deriving microplastic toxicity thresholds: Application to microplastic risk assessment of school-aged children in Pudong, Shanghai20
Dermal repeated dose toxicity study of the anti-breast cancer drug Formestane cream in Bama minipig20
An in vitro protocol to characterise the resistance of food proteins to intestinal digestion20
Vallaris solanacea induces mitochondrial mediated apoptosis in HL-60 human promyelocytic leukemia cells20
Update to RIFM fragrance ingredient safety assessment, 1,1-diethoxyhexane, CAS registry number 3658-93-319
High fructose-induced skeletal muscle insulin resistance could be alleviated by berberine via AMPD1 and ADSL19
Potential exacerbation of polycystic ovary syndrome by saccharin sodium Via taste receptors in a letrozole rat model19
RIFM fragrance ingredient safety assessment, thymol, CAS Registry Number 89-83-819
Update to RIFM fragrance ingredient safety assessment, isobutyl acetate, CAS Registry Number 110-19-019
Update to RIFM fragrance ingredient safety assessment, methyl undec-10-enoate, CAS registry number 111-81-919
RIFM fragrance ingredient safety assessment, benzoic acid, 2-[(2-phenylethylidene)amino]-, methyl ester, CAS Registry Number 67785-76-619
RIFM fragrance ingredient safety assessment, 3-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexan-1-ol, CAS registry number 3407-42-919
Review of the oral toxicity of cannabidiol (CBD)19
Perfluorohexane sulfonate (PFHxS) induces liver cytotoxicity by activating autophagy and endoplasmic reticulum stress-regulated mitochondrial pathway apoptosis19
Editorial Board19
RIFM fragrance ingredient safety assessment, nopyl acetate, CAS registry number 128-51-819
Update to RIFM fragrance ingredient safety assessment, isoeugenol, CAS registry number 97-54-119
RIFM fragrance ingredient safety assessment, 6,10-dodecadienal, 3,7,11-trimethyl-, (3S,6E)-, CAS registry number 194934-66-219
RIFM fragrance ingredient safety assessment, ethyl benzoylacetate, CAS registry number 94-02-019
Update to RIFM fragrance ingredient safety assessment, methyl 2-octynoate, CAS Registry Number 111-12-619
Mitochondrial damage precedes the changes of glutathione metabolism in CdCl2 treated neuronal SH-SY5Y cells19
Dietary exposure to mixtures of chemicals in the first year of life and allergic and respiratory diseases up to 8 years in the French EDEN mother-child cohort19
Neurotoxicity of dibutyl phthalate in zebrafish larvae: Decreased energy acquisition by neurons19
In vitro cytotoxicity assessment of carbonaceous gels for bone marrow mesenchymal stem cells19
RIFM fragrance ingredient safety assessment, anisyl acetate (isomer unspecified), CAS Registry Number 1331-83-519
20-Week intramuscular toxicity study of rotigotine behenate extended-release microspheres for injection via intramuscular injection in cynomolgus monkeys18
A review of anorexia induced by T-2 toxin18
Stochastic health risk assessment of aflatoxin M1 in cow's milk among Lebanese population18
An untargeted metabolomics study of cardiac pathology damage in rats caused by low selenium diet alone or in combination with T-2 toxin18
Estimated long-term dietary exposure to cadmium from consumption of spinach in the United States: A probabilistic assessment18
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