Food and Chemical Toxicology

Papers
(The TQCC of Food and Chemical Toxicology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
RIFM fragrance ingredient safety assessment, acetaldehyde ethyl cis-3-hexenyl acetal, CAS Registry Number 28069-74-1318
Gut-gonad crosstalk in mice exposed to a “chemical cocktail” combining metabolomics and microbial profile by amplicon sequencing236
Update to RIFM fragrance ingredient safety assessment, 3-methylbutanal diethyl acetal, CAS Registry Number 3842-03-3196
Editorial Board163
Sustained high expression of NRF2 inhibits cell apoptosis in arsenite-transformed human keratinocytes160
Editorial Board156
Investigation and evaluation of gastrointestinal toxicity biomarkers in rats with different sites of gastrointestinal injury156
Theaflavin alleviates cisplatin-induced nephrotoxicity: Targeting SIRT1/p53/FOXO3a/Nrf2 signaling and the NF-kB inflammatory cascade152
Update to RIFM fragrance ingredient safety assessment, 3-tert-butylcyclohexyl acetate, CAS Registry Number 31846-06-7138
RIFM natural complex substance (NCS) fragrance ingredient safety assessment, lavandin abrialis, CAS registry number 8022-15-9, RIFM ID 1048554131
Cardiac oxylipin perturbances in response to 2-monochloropropane-1,3-diol exposure are ameliorated by dietary adequacy of the essential n-3 fatty acid, α-linolenic acid123
The “steric-like” inhibitory effect and mechanism of doxycycline on florfenicol metabolism: Interaction risk117
Substance depletion of monoterpenes in the mouse lymphoma assay: Quantification, impact and mitigation117
Microcystin-LR exposure interfered maintenance of colonic microenvironmental homeostasis in rat115
Assessing the toxic dose of the potent antioxidant 3,5-dihydroxy-4-methoxybenzyl alcohol in rats113
Assessment of human health risk concerning edible plants contamination with toxic elements around functional and derelict mines112
NRF-2α and mitophagy underlie enhanced mitochondrial functions and biogenesis induced by T-2 toxin in GH3 cells104
Gene expression profiles related to apoptosis and levels of DNA oxidative damage in primary dermal fibroblast cells (ATCC® PCS-201-012TM) treated with zirconium oxide nanoparticles97
Preclinical toxicity evaluation of the novel anti-hypertensive compound KSD17901993
The role of GSK3β signaling mediated lysosomal biosynthesis dysregulation in fluoride-induced neurological impairment85
Sinomenine synergistically enhances 5-Fu anticancer effects in oral cancer through modulating the miR-140-5p-PDK1-anaerobic glycolysis pathway82
Farnesol prevents chlorpyrifos nephrotoxicity by modulating inflammatory mediators, Nrf2 and FXR and attenuating oxidative stress80
Toxicity assessment of heavy metals translocation in maize grown in the Ganges delta floodplain soils around the Payra power plant in Bangladesh80
Update to RIFM fragrance ingredient safety assessment, octyl butyrate, CAS Registry Number 110-39-479
RIFM fragrance ingredient safety assessment, furfural, CAS Registry Number 98-01-175
RIFM fragrance ingredient safety assessment, 2-methylpropyl 2-methylbutyrate, CAS Registry Number 2445-67-271
RIFM fragrance ingredient safety assessment, ethyl 2-ethylhexanoate, CAS Registry Number 2983-37-165
Update to RIFM fragrance ingredient safety assessment, 1-naphthalenol, 1,2,3,4,4a,5,8,8a-octahydro-2,2,6,8-tetramethyl-, CAS Registry Number 103614-86-464
RIFM fragrance ingredient safety assessment, bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-, benzoate, CAS Registry Number 55066-54-162
RIFM fragrance ingredient safety assessment, ethyl valerate, CAS Registry Number 539-82-261
Update to RIFM fragrance ingredient safety assessment, 2H-inden-2-one, 1,3-dihydro-, CAS Registry Number 615-13-461
Update to RIFM fragrance ingredient safety assessment, 4-methylpentanoic acid, CAS Registry Number 646-07-160
Update to RIFM fragrance ingredient safety assessment, hexyl isovalerate, CAS Registry Number 10032-13-058
Update to RIFM fragrance ingredient safety assessment, pentyl benzoate, CAS Registry Number 2049-96-958
Kidney toxicity and transcriptome analyses of male ICR mice acutely exposed to the mushroom toxin α-amanitin58
RIFM fragrance ingredient safety assessment, 3-buten-2-one, 4-(2,2,3-trimethyl-6-methylenecyclohexyl)-, CAS registry number 79-68-558
RIFM fragrance ingredient safety assessment, ethyl decanoate, CAS Registry Number 110-38-357
Editorial Board56
RIFM fragrance ingredient safety assessment, isoeugenyl methyl ether, CAS Registry Number 93-16-356
Corrigendum to “In vitro and in vivo antitumor effects of Peanut agglutinin through induction of apoptotic and autophagic cell death” [Food Chem. Toxicol. 2014 64 369-77]55
EGCG exposure during pregnancy affects uterine histomorphology in F1 female mice and the underlying mechanisms55
RIFM fragrance ingredient safety assessment, 5,8-methano-2H-1-benzopyran, 6(or 7)-ethylideneoctahydro-, [4aR,5S,8S,8aS(or 4aR,5R,8S,8aR)]-rel-, CAS Registry Number 943723-15-754
Neurotoxic effect of nalufin on the histology, ultrastructure, cell cycle and apoptosis of the developing chick embryo and its amelioration by selenium53
RIFM fragrance ingredient safety assessment, cis-3-hexenyl isobutyrate, CAS Registry Number 41519-23-752
RIFM fragrance ingredient safety assessment, styrene, CAS Registry Number 100-42-552
RIFM fragrance ingredient safety assessment, 2-pentylcyclopentan-1-ol, CAS Registry Number 84560-00-951
RIFM fragrance ingredient safety assessment, o-(Methylthio)-phenol, CAS Registry Number 1073-29-651
RIFM fragrance ingredient safety assessment, hex-3-enyl acetate, CAS Registry Number 1708-82-351
RIFM fragrance ingredient safety assessment, isopentyl 2-methylcrotonate (E), CAS Registry Number 41519-18-050
RIFM fragrance ingredient safety assessment, 2-acetyl-3-methylpyrazine, CAS Registry number 23787-80-650
Ultra-fast liquid chromatography detection of β-N-methylamine-l-alanine and its isomers in cycad seeds and cyanobacterial symbionts for neurotoxic risk assessment50
RIFM fragrance ingredient safety assessment, methyl butyrate, CAS registry number 623-42-750
Inhalation toxicity of thermal transformation products formed from e-cigarette vehicle liquid using an in vitro lung model exposed at the Air–Liquid Interface48
Gallic, ellagic acids and their oral combined administration induce kidney, lung, and heart injury after acute exposure in Wistar rats47
Combined environmental relevant exposure to perfluorooctanoic acid and zinc sulfate enhances apoptosis through binding with endogenous antioxidants in Daphnia magna46
Ouabain inhibitor rostafuroxin attenuates dextromethorphan-induced manic potential46
Identification of non-volatile non-intentionally added substances from polyester food contact coatings and genotoxicity assessment of polyester coating's migrates45
Evaluation of cigarette smoke-induced oxidative stress and inflammation in BEAS-2B cells based on a lung microfluidic chip45
Lithium suppresses the Ras-Raf-MEK-ERK signaling in CD4 T cells and impairs the humoral immune system44
Rutin, a natural flavonoid glycoside, ameliorates zearalenone induced liver inflammation via inhibiting lipopolysaccharide gut leakage and NF-κB signaling pathway in mice44
Tectorigenin ameliorated high-fat diet-induced nonalcoholic fatty liver disease through anti-inflammation and modulating gut microbiota in mice44
Low-dose benzo[a]pyrene exposure induces hepatic lipid deposition through LCMT1/PP2Ac-mediated autophagy inhibition43
MiR-93 alleviates DEHP plasticizer-induced neurotoxicity by negatively regulating TNFAIP1 and inhibiting ubiquitin-mediated degradation of CK2β43
Probiotic lactobacilli attenuate oxysterols-induced alteration of intestinal epithelial cell monolayer permeability: Focus on tight junction modulation43
Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway42
Diisobutyl phthalate (DiBP)-induced male germ cell toxicity and its alleviation approach42
Bisphenol A and its analogue bisphenol S exposure reduce estradiol synthesis via the ROS-mediated PERK/ATF4 signaling pathway41
Inhibition of human sulfotransferases (SULTs) by per- and polyfluoroalkyl substances (PFASs) and structure-activity relationship40
Comparative detection of E. coli, B. subtilis and their mixture in yam samples by ATP bioluminescence and SERS methods40
Functional evaluation of fibroblast-to-myofibroblast transition as an in vitro screening tool for pulmonary fibrosis40
No-observed adverse effect levels of deoxynivalenol and aflatoxin B1 in combination induced immune inhibition and apoptosis in vivo and in vitro39
Acrylamide in food: Occurrence, metabolism, molecular toxicity mechanism and detoxification by phytochemicals39
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice39
From food-to-human microplastics and nanoplastics exposure and health effects: A review on food, animal and human monitoring data39
Global review, meta-analysis and health risk assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in chicken kebab using Monte Carlo simulation method39
Curcumin mitigates gentamicin induced-renal and cardiac toxicity via modulation of Keap1/Nrf2, NF-κB/iNOS and Bcl-2/BAX pathways39
Predicting chemicals’ toxicity pathway of female reproductive disorders using AOP7 and deep neural networks38
RIFM fragrance ingredient safety assessment, acetylcarene, CAS Registry Number 3608-11-538
Corrigendum to “Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway” [Food and Chemical Toxico38
Characterizing the risk related to the exposure to methylmercury over a lifetime: A global approach using population internal exposure38
Kaempferol improves recurrent spontaneous abortion outcomes and prevents oxidative stress damage by inhibiting the NF-kB signaling pathway37
In response to the Letter to the Editor from Xiao regarding our article, “FEMA GRAS assessment of natural flavor complexes: Asafetida oil, garlic oil and onion oil”37
N-(2-ozoazepan-3-yl)-pyrrolidine-2-carboxamide, a novel Octopus vulgaris ink-derived metabolite, exhibits a pro-apoptotic effect on A549 cancer cell line and inhibits pro-inflammatory markers37
Melatonin protects against diclofenac induced oxidative stress mediated myocardial toxicity in rats: A mechanistic insight36
Update to RIFM fragrance ingredient safety assessment, nonyl acetate, CAS registry number 143-13-536
Corrigendum to “Effects of gelatin-based antifreeze peptides on cell viability and oxidant stress of Streptococcus thermophilus during cold stage” [Food Chem. Toxicol. 136 (2020) 111056]36
RIFM fragrance ingredient safety assessment, p-isopropyl phenylacetaldehyde, CAS Registry Number 4395-92-035
RIFM fragrance ingredient safety assessment, cycloionone, CAS Registry Number 5552-30-735
RIFM fragrance ingredient safety assessment, 2,4,4,7-tetramethylnona-6,8-diene-3-one-oxime, CAS Registry Number 81783-01-935
Epigallocatechin gallate-rich fraction alleviates histamine-induced neurotoxicity in rats via inactivating caspase-3/JNK signaling pathways35
RIFM fragrance ingredient safety assessment, germacrene D, CAS Registry Number 23986-74-535
Update to RIFM fragrance ingredient safety assessment, methyl benzoate, CAS Registry Number 93-58-334
RIFM fragrance ingredient safety assessment, dodecahydro-3,8,8,11a-tetramethyl-5H-3,5a-epoxynaphth[2,1-c]oxepin, CAS Registry Number 57345-19-434
Update to RIFM fragrance ingredient safety assessment, p-tolyl alcohol, CAS Registry Number 589-18-434
RIFM fragrance ingredient safety assessment, 3-phenyl-3-buten-1-yl acetate, CAS Registry Number 7306-12-933
RIFM fragrance ingredient safety assessment, ω-6-hexadecenlactone, CAS Registry Number 7779-50-233
Update to RIFM fragrance ingredient safety assessment, linalyl acetate, CAS registry number 115-95-733
RIFM fragrance ingredient safety assessment, cis- and trans-p-1(7),8-menthadien-2-yl acetate, CAS registry number 71660-03-233
Update to RIFM fragrance ingredient safety assessment, methyl phenylacetate, CAS Registry Number 101-41-733
RIFM fragrance ingredient safety assessment, 3-(p-isopropylphenyl)propionaldehyde, CAS registry number 7775-00-033
RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, tangelo oil, expressed, CAS Registry Number 72869-73-9, RIFM ID 931-G2.533
Hyperoside attenuates Cd-induced kidney injury via inhibiting NLRP3 inflammasome activation and ROS/MAPK/NF-κB signaling pathway in vivo and in vitro32
Update to RIFM fragrance ingredient safety assessment, ethyl benzoate, CAS Registry Number 93-89-032
RIFM fragrance ingredient safety assessment, 4-acetoxy-2,5-dimethyl-3(2H)furanone, CAS Registry Number 4166-20-532
RIFM fragrance ingredient safety assessment, o-methoxybenzaldehyde, CAS Registry Number 135-02-432
CDKN1A promotes Cis-induced AKI by inducing cytoplasmic ROS production and ferroptosis32
Deoxynivalenol upregulates hypoxia-inducible factor-1α to promote an “immune evasion” process by activating STAT3 signaling32
RIFM fragrance ingredient safety assessment, patchouli alcohol, CAS Registry Number 5986-55-032
Mitigating Bisphenol-Induced Neurotoxicity: Exploring the Therapeutic Potential of Diosmin in Zebrafish Larvae31
Triptolide exposure triggers ovarian inflammation by activating cGAS-STING pathway and decrease oocyte quality in mouse31
RIFM fragrance ingredient safety assessment, benzoic acid, 2-[[3-(4-methoxyphenyl)-2-methylpropylidene]amino]-, methyl ester, CAS registry number 111753-62-931
Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus31
Bisphenol S exposure induces cytotoxicity in mouse Leydig cells31
RIFM fragrance ingredient safety assessment, (1aα,4α,7aα)-1a,3,3,4,6,6-hexamethyl-1a,2,3,4,5,6,7,7a-octahydronapth[3,3-b]oxirene, CAS Registry Number 94400-98-331
RIFM fragrance ingredient safety assessment, cedryl formate, CAS Registry Number 39900-38-431
Active compounds of licorice ameliorate microplastics-induced intestinal damage by targeting FADD31
Update to RIFM fragrance ingredient safety assessment, menthyl acetate (isomer unspecified), CAS registry number 16409-45-331
Toxicology of Dyes: Editorial Introduction31
Non-allergenic mixed T cell epitope peptides for preventing Scy p 9 allergic reactions30
Pithecellobium dulce induces apoptosis and reduce tumor burden in experimental animals via regulating pro-inflammatory cytokines and anti-apoptotic gene expression30
Multivariate analysis of potentially toxic metal contents in soil and vegetables: Enrichment, bioconcentration, translocation from soil to vegetables, and assessment of human health toxicity30
Update to RIFM fragrance ingredient safety assessment, isobutyl propionate, CAS Registry Number 540-42-130
RIFM fragrance ingredient safety assessment, 2-trans-6-cis-dodecadienal, CAS Registry Number 21662-13-530
Chronic exposure to B[a]P induces malignant transformation of breast epithelial cells through the mechanism via TGF-β signaling pathway30
Enniatin B and beauvericin affect intestinal cell function and hematological processes in Atlantic salmon (Salmo salar) after acute exposure30
RIFM fragrance ingredient safety assessment, 3-mercaptohexyl acetate, CAS Registry Number 136954-20-630
RIFM fragrance ingredient safety assessment, 4-methoxy-α-methylbenzenepropanal, CAS Registry Number 5462-06-629
Mycotoxins in raw materials, beverages and supplements of botanicals: A review of occurrence, risk assessment and analytical methodologies29
Editorial Board29
Update to RIFM fragrance ingredient safety assessment, α,2,2,3-tetramethylcyclopent-3-ene-1-butyraldehyde, CAS Registry Number 65114-03-629
RIFM fragrance ingredient safety assessment, 1-formyl-1-methyl-4-(4-methyl-pentyl)-3-cyclohexene, CAS Registry Number 66327-54-629
RIFM fragrance ingredient safety assessment, 2-phenylhexanenitrile, CAS registry number 3508-98-329
RIFM fragrance ingredient safety assessment, sssmenthadiene-7-methyl formate, CAS registry number 68683-20-529
RIFM fragrance ingredient safety assessment, benzene, 1-(dimethoxymethyl)-4-methoxy-, CAS Registry Number 2186-92-729
RIFM fragrance ingredient safety assessment, phenethyl propionate, CAS Registry Number 122-70-329
RIFM fragrance ingredient safety assessment, 3-methyl-2-butenyl salicylate, CAS Registry Number 68555-58-829
Editorial Board28
RIFM fragrance ingredient safety assessment, ethyl butyrate, CAS registry number 105-54-428
RIFM fragrance ingredient safety assessment, bisabolene, CAS registry number 495-62-528
RIFM fragrance ingredient safety assessment, 1,1-dimethyl-2-phenylethyl acetate, CAS registry number 151-05-328
RIFM fragrance ingredient safety assessment, p-mentha-1,3-diene, CAS Registry Number 99-86-528
RIFM fragrance ingredient safety assessment, oxacyclopentadec-10-en-2-one, 13-methyl-, CAS Registry Number 329925-33-928
RIFM fragrance ingredient safety assessment, 2-ethylhexanal, CAS Registry Number 123-05-728
Alcohol induces hepatocytes necroptosis through the LC3/RIPK1/RIPK3 pathway27
Immunoproteasome subunit PSMB8 regulates microglia-mediated neuroinflammation upon manganese exposure by PERK signaling27
Probiotic cultures as a potential protective strategy against the toxicity of environmentally relevant chemicals: State-of-the-art knowledge27
Impact of food matrices on the characteristics and cellular toxicities of ingested nanoplastics in a simulated digestive tract27
Update to RIFM fragrance ingredient safety assessment, trans-2-hexenoic acid, CAS Registry Number 13419-69-727
Unravelling the anti-inflammatory and antioxidant effects of standardized green and black caffeinated coffee, tea, and their mixtures in an obese male rat model: Insights from biochemical, metabolomic27
Fertility-enhancing effects of inositol & vitamin C on cisplatin induced ovarian and uterine toxicity in rats via suppressing oxidative stress and apoptosis27
Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan27
Piceatannol upregulates USP14-mediated GPX4 deubiquitination to inhibit neuronal ferroptosis caused by cerebral ischemia-reperfusion in mice27
Rapid identification of counterfeited beef using deep learning-aided spectroscopy: Detecting colourant and curing agent adulteration27
Experimental evaluation of favipiravir (T-705)-induced liver and kidney toxicity in rats27
Bisphenol a exposure decreases learning ability through the suppression of mitochondrial oxidative phosphorylation in the hippocampus of male mice26
Beyond monitoring: Integrating risk, benefit, and biomonitoring in Greek dietary exposure to dioxins and PCBs26
Organophosphate esters and their metabolites in Beijing total diets: Occurrence, time trend, and dietary exposure assessment26
Hyoscyamine induces developmental toxicity by disrupting metabolism in zebrafish embryo (Danio rerio)26
Glyphosate and AMPA-induced apoptosis and epigenetic alterations in HepG2 Cells: Upregulation of p53-BAX-CASP pathways26
Environmental toxicity risk evaluation of nitroaromatic compounds: Machine learning driven binary/multiple classification and design of safe alternatives26
Liensinine, a alkaloid from lotus plumule, mitigates lipopolysaccharide-induced sepsis-associated encephalopathy through modulation of nuclear factor erythroid 2-related factor-mediated inflammatory b26
Chlorinated organophosphorus flame retardants-induced mitochondrial abnormalities and the correlation with progesterone production in mLTC-1 cells26
RIFM fragrance ingredient safety assessment, d,l-menthone 1,2-glycerol ketal, CAS Registry Number 63187-91-726
Apigenin in cancer therapy: From mechanism of action to nano-therapeutic agent26
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro26
Emamectin benzoate-induced toxicity affects intestinal epithelial integrity involving apoptosis25
Association between Di-2-ethylhexyl phthalate and nonalcoholic fatty liver disease among US adults: Mediation analysis of body mass index and waist circumference in the NHANES25
Development and application of an interactive generic physiologically based pharmacokinetic (igPBPK) model for adult beef cattle and lactating dairy cows to estimate tissue distribution and edible tis25
Acute ivermectin toxicity on skin and brain tissue of adult albino rats: Evaluation of the role of Flumazenil and Vitamin C as new treatment modalities25
Determination of acrylamide levels in chips/crisps on the Italian market and exposure risk assessment25
Isochlorogenic acid A ameliorated lead-induced anxiety-like behaviors in mice by inhibiting ferroptosis-mediated neuroinflammation via the BDNF/Nrf2/GPX4 pathways25
Update to RIFM fragrance ingredient safety assessment, benzyl formate, CAS Registry Number 104-57-425
RIFM fragrance ingredient safety assessment, 1-propanol, 2-methyl-3-[(1,7,7-trimethylbicyclo-[2.2.1]hept-2-yl)oxy]-, CAS Registry Number 128119-70-025
Weighted analysis of 2′-fucosyllactose, 3-fucosyllactose, lacto-N-tetraose, 3′-sialyllactose, and 6′-sialyllactose concentrations in human milk25
High throughput screening of bisphenols and their mixtures under conditions of low-intensity adipogenesis of human mesenchymal stem cells (hMSCs)25
In silico and in vitro safety assessment of a fungal biomass from Rhizomucor pusillus for use as a novel food ingredient25
Therapeutic potential of 2S-hesperidin against the hepatotoxic effects of dichlorvos in rats25
Update to RIFM fragrance ingredient safety assessment, acetaldehyde, diphenethyl acetal, CAS Registry Number 122-71-425
RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]deca-3,6-diene, 2,6,9,10-tetramethyl-, CAS Registry Number 71078-31-424
RIFM fragrance ingredient safety assessment, 3-hexanone, 5-mercapto-5-methyl-, CAS Registry Number 851768-51-924
Update to RIFM fragrance ingredient safety assessment, hexanoic acid, 4-methyl-, CAS registry number 1561-11-124
RIFM fragrance ingredient safety assessment, butyl salicylate, CAS Registry Number 2052-14-424
RIFM fragrance ingredient safety assessment, methyl sorbate, CAS Registry Number 689-89-424
RIFM fragrance ingredient safety assessment, 11-oxahexadecanolide, CAS Registry Number 3391-83-124
Update to RIFM fragrance ingredient safety assessment, isoamyl hexanoate, CAS registry number 2198-61-024
RIFM fragrance ingredient safety assessment, pyridine, 4-[1(4-,5 or 6)-methylbicyclo[2.2.1]hept-5-en-2-yl]-, CAS Registry Number 862079-91-224
RIFM fragrance ingredient safety assessment, 3,3,5-trimethylcyclohexyl ethyl ether, CAS Registry Number 67583-77-124
RIFM fragrance ingredient safety assessment, benzoic acid, 2-hydroxy-5-methyl-, methyl ester, CAS Registry Number 22717-57-324
RIFM fragrance ingredient safety assessment, 2,3,5-trimethylpyrazine, CAS registry number 14667-55-123
Vallaris solanacea induces mitochondrial mediated apoptosis in HL-60 human promyelocytic leukemia cells23
Editorial Board23
Choice of experimental model determines translational impact: The link between bisphenol A and cardiotoxicity23
Maternal exposure to a glyphosate-based herbicide impairs placental development through endoplasmic reticulum stress in mice23
RIFM fragrance ingredient safety assessment, methyl p-methylbenzoate, CAS Registry Number 99-75-223
RIFM fragrance ingredient safety assessment, 4-thujanol, CAS Registry Number 546-79-223
Update to RIFM fragrance ingredient safety assessment, dimethyl succinate, CAS Registry Number 106-65-023
RIFM fragrance ingredient safety assessment, thymol, CAS Registry Number 89-83-823
Safety and toxicologic evaluation of Edible Pongamia Oil: A novel food ingredient23
Protective role of the dried white mulberry extract on the reproductive damage and fertility in rats treated with carmustine23
Editorial Board22
RIFM fragrance ingredient safety assessment, 3-phenylpropionaldehyde, CAS Registry Number 104-53-022
RIFM fragrance ingredient safety assessment, methyl 4(or 1)-isopropyl-1(or 4)-methylbicyclo[2.2.2]oct-5-ene-2-carboxylate, CAS Registry Number 68966-86-922
Fluquinconazole disrupts calcium and mitochondrial homeostasis, leading to bovine mammary epithelial cell death22
Risk assessment of potentially toxic trace elements via consumption of dairy products sold in the city of Yerevan, Armenia22
Update to RIFM fragrance ingredient safety assessment, β-caryophyllene alcohol, CAS registry number 472-97-922
Normolipidic diet containing deep-fried saturated and unsaturated fatty acids rich edible oils promotes metabolic dysregulation and inflammatory microenvironment in Wistar rats22
RIFM fragrance ingredient safety assessment, d-8-p-menthene-1,2-epoxide, CAS Registry Number 1195-92-222
RIFM fragrance ingredient safety assessment, isolongifolene oxide, CAS Registry Number 26619-69-222
In vitro toxicological assessment of aerosols from indirectly heated tobacco products using a solvent-free extraction method22
Lysosomal dependent transcytosis of polystyrene nanoplastics within macrophages22
RIFM fragrance ingredient safety assessment, sclareolide, CAS Registry Number 564-20-522
RIFM fragrance ingredient safety assessment, cis-jasmone, CAS registry number 488-10-822
Enantioselective toxicity effect and mechanism of hexaconazole enantiomers to human breast cancer cells22
Genetic variations of CYP3A4 on the metabolism of itraconazole in vitro22
Mitochondrial damage precedes the changes of glutathione metabolism in CdCl2 treated neuronal SH-SY5Y cells22
Bioactive extract of Morchella esculenta ameliorates cyclophosphamide-induced mitochondrial dysfunction and cardiotoxicity by modulating KEAP1/NRF2 and pro-inflammatory genes expression21
Tri-ortho-cresyl phosphate causes glucose intolerance and insulin resistance in mice by inducing oxidative stress21
Potential exacerbation of polycystic ovary syndrome by saccharin sodium Via taste receptors in a letrozole rat model21
A time-course study of microglial activation and dopaminergic neuron loss in the substantia nigra of mice with paraquat-induced Parkinson's disease21
Potential underlying mechanisms of ethambutol induced optic neuropathy: Evidence from in vitro to clinical studies21
Atrazine-induced oxidative damage via modulating xenobiotic-sensing nuclear receptors and cytochrome P450 systems in cerebrum and antagonism of lycopene21
Dietary exposure to mixtures of chemicals in the first year of life and allergic and respiratory diseases up to 8 years in the French EDEN mother-child cohort21
An in vitro protocol to characterise the resistance of food proteins to intestinal digestion21
Metabolic effects of chronic exposure to environmentally relevant concentrations of N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) in mice during diet-induced obesity progression21
Review of the oral toxicity of cannabidiol (CBD)20
Dermal repeated dose toxicity study of the anti-breast cancer drug Formestane cream in Bama minipig20
Bisphenol S exposure induces intestinal inflammation via altering gut microbiome20
Ultrasensitive electrochemical sensor for detection of rutin antioxidant by layered Ti3Al0.5Cu0.5C2 MAX phase20
RIFM fragrance ingredient safety assessment, α-pinene, CAS Registry Number 80-56-820
Pharmacokinetics and 28-day repeated-dose toxicity of enniatin B after oral administration in mice20
Sub-acute administration of metal-organic Framework-5 induces behavioral impairments and augments the levels of oxidative stress and inflammation in the brain of rats20
Carcinogenic and non-carcinogenic risks caused by rice contamination with heavy metals and their effect on the prevalence of cardiovascular disease (Using machine learning)20
Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived 20
Mechanisms of PDC-induced testicular Toxicity: Oxidative stress, steroidogenic suppression, and modulation by ZnO-NP/TEO synergy20
The Austrian children's biomonitoring survey 2020 Part B: Mycotoxins, phytotoxins, phytoestrogens and food processing contaminants20
Perfluorohexane sulfonate (PFHxS) induces liver cytotoxicity by activating autophagy and endoplasmic reticulum stress-regulated mitochondrial pathway apoptosis20
PAK1 mediates ivermectin-induced DNA damage in porcine oocytes during meiotic maturation20
Neurotoxicity of dibutyl phthalate in zebrafish larvae: Decreased energy acquisition by neurons20
Endocrine disruptor hexachlorobenzene induces cell migration and invasion, and enhances aromatase expression levels in human endometrial stromal cells20
Exposure to short-, medium-, and long-chain chlorinated paraffins for infant via cow infant formula, goat infant formula and baby food19
RIFM fragrance ingredient safety assessment, nopyl acetate, CAS registry number 128-51-819
Update to RIFM fragrance ingredient safety assessment, hydroxycitronellal dimethyl acetal, CAS Registry number 141-92-419
RIFM fragrance ingredient safety assessment, benzoic acid, 2-[(2-phenylethylidene)amino]-, methyl ester, CAS Registry Number 67785-76-619
Editorial Board19
In vitro cytotoxicity assessment of carbonaceous gels for bone marrow mesenchymal stem cells19
Update to RIFM fragrance ingredient safety assessment, 1,1-diethoxyhexane, CAS registry number 3658-93-319
Update to RIFM fragrance ingredient safety assessment, isobutyl acetate, CAS Registry Number 110-19-019
Investigation of eight cellulose nanomaterials’ impact on Differentiated Caco-2 monolayer integrity and cytotoxicity19
RIFM fragrance ingredient safety assessment, 3-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexan-1-ol, CAS registry number 3407-42-919
RIFM fragrance ingredient safety assessment, ethyl benzoylacetate, CAS registry number 94-02-019
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