Pharmacotherapy

Papers
(The median citation count of Pharmacotherapy is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Changes in serum potassium in people with type 2 diabetes taking sodium‐glucose co‐transporter‐2 inhibitors111
Safety and efficacy of cefiderocol for off‐label treatment indications: A systematic review104
Empiric dosing strategies to predict lamotrigine concentrations during pregnancy76
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Update and narrative review of avian influenza (H5N1) infection in adult patients57
Characterization of lamotrigine disposition changes during and after pregnancy in women with epilepsy52
Hydroxyurea treatment for sickle cell anemia during pregnancy and lactation: Current evidence and knowledge gaps43
Warfarin dosage in a postpartum woman while breastfeeding: A case report41
Correction to “Relationship of the Revised Anticholinergic Drug Scale With Cultured Cell‐Based Serum Anticholinergic Activity and Cognitive Measures in Older Adults With Mild Cognitive Impairment or R40
Assessment and management of iatrogenic withdrawal syndrome and delirium in pediatric intensive care units across Europe: An ESPNIC survey35
Acid‐suppressive drugs: A systematic review and network meta‐analysis of their nocturnal acid‐inhibitory effect35
Oral fluoroquinolones and risk of aortic aneurysm or dissection: A nationwide population‐based propensity score‐matched cohort study34
A Multicenter, Open‐Label Study to Assess the Safety of Nebulized Tissue Plasminogen Activator for the Acute Treatment of Pediatric Plastic Bronchitis: The PLATyPuS Trial32
Statin‐associated muscle symptoms—A review: Individualizing the approach to optimize care32
Comparative safety and efficacy of bisphosphonates, denosumab, and parathyroid hormone analogs for osteoporosis following lung transplantation31
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Comment on “Evaluation of the safety and tolerability of intravenous undiluted levetiracetam at a pediatric institution”29
Reduced risk of NSAID‐Induced adverse events with concomitant use of misoprostol (MICRO study)28
Impact of concurrent gabapentin or pregabalin with high‐dose melphalan in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplant28
Optimal starting dosing regimen of intravenous oxytocin for labor induction based on the population kinetic‐pharmacodynamic model of uterine contraction frequency27
Evaluation of the safety and tolerability of intravenous undiluted levetiracetam at a pediatric institution27
Response to comment on “Dosing implications for liposomal amphotericin B in pregnancy”23
Patient safety outcomes for continuous infusion vancomycin as outpatient parenteral antimicrobial therapy23
Determination of vancomycin exposure target and individualized dosing recommendations for critically ill patients undergoing continuous renal replacement therapy22
Role of maternal COVID‐19 vaccination in providing immunological protection to the newborn22
Correlation Between Analgesic and Sedative Drug Withdrawal and Salivary Cortisol Levels in Children in PICUs : A Prospective Cohort Study22
Biomarkers in the intensive care setting: A focus on using procalcitonin and C‐reactive protein to optimize antimicrobial duration of therapy22
Reversal of apixaban and rivaroxaban with andexanet alfa prior to invasive or surgical procedures21
Consensus recommendations for the use of novel antiretrovirals in persons with HIV who are heavily treatment‐experienced and/or have multidrug‐resistant HIV‐1: Endorse21
Synthetic Data–Driven Early Prediction Framework for Acute Kidney Injury in Patients Receiving Vancomycin and Ceftazidime/Avibactam19
Pharmacokinetics of Ceftolozane/Tazobactam in Patients With Partial‐ and Full‐Thickness Skin Burns19
Pharmacotherapy research landscape and knowledge gaps of opioids in maternal and pediatric populations19
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Effect of P2Y12 Inhibitors on Major Adverse Cardiovascular Events After Coronary Artery Bypass Graft Surgery: A Population‐Based Cohort Study18
Effect of creatine monohydrate on motor function in children with facioscapulohumeral muscular dystrophy: A multicenter, randomized, double‐blind placebo‐controlled crossover trial18
Role of the gut microbiome in cardiovascular drug response: The potential for clinical application17
Early combination therapy with immunoglobulin and steroids is associated with shorter ICU length of stay in Multisystem Inflammatory Syndrome in Children (MIS‐C) associated with 17
Adverse Effects of Antidepressant Medications and their Management in Children and Adolescents17
Cefazolin in the treatment of central nervous system infections: A narrative review and recommendation16
Approaches to Precision‐based Anticoagulation management in the critically Ill16
Pharmacokinetic and pharmacodynamic evaluation of sulbactam‐durlobactam in a critically ill patient on continuous venovenous hemofiltration infected with carbapenem‐resistant Ac16
Impact of dexmedetomidine in conjunction with a weaning protocol on post‐surgical opioid use in a neonatal intensive care unit15
Use of proton pump inhibitors and risk of severe COVID‐19: A case–control study in United States Medicare beneficiaries15
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Proton pump inhibitor concomitant use to prevent oxaliplatin‐induced peripheral neuropathy: Clinical retrospective cohort study15
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Comment on “Intravenous ketamine successfully treats treatment‐resistant catatonia in schizophrenia: A case report”15
Impact of concomitant fluconazole on direct oral anticoagulant bleeding risk14
Oritavancin for Treatment of Osteomyelitis: A Systematic Review and Meta‐Analysis of Observational Studies14
Pain management considerations in patients living with both pain syndromes and cardiovascular diseases and disorders14
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Current therapies and challenges for the treatment of Staphylococcus aureus biofilm‐related infections14
Reply to Comment on: Tacrolimus in the treatment of childhood nephrotic syndrome: Machine learning detects novel biomarkers and predicts efficacy14
Hydrocortisone versus vasopressin for the management of adult patients with septic shock refractory to norepinephrine: A multicenter retrospective study14
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Efficacy and safety of factor Xa inhibitors in low body weight patients13
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Kidney Damage Biomarkers: A Missing Piece of the Diagnostic and Management Puzzle for Acute Drug‐Related Kidney Diseases13
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A dose‐escalation clinical trial of intranasal ketamine for uncontrolled cancer‐related pain13
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Lithium Augmentation in Treatment‐Resistant Depression: A Qualitative Review of the Literature12
Performance of different body weights in the Cockcroft‐Gault equation in critically ill patients with and without augmented renal clearance: A multicenter cohort12
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Fluoroquinolones and the risk of aortic aneurysm or dissection: A population‐based propensity score‐matched German cohort study12
Critique of “Angiotensin‐converting enzyme inhibitors reduce community‐acquired pneumonia hospitalization and mortality”12
Caring for two in the ICU: Pharmacologic management of pregnancy‐related complications11
Scoping review of rational polytherapy in patients with drug‐resistant epilepsy11
Effects of statin therapy and treatment duration on cardiovascular disease risk in patients with nephrotic syndrome: A nested case–control study11
Risks of serious adverse events and kidney injury in patients treated with ibandronate: A systematic review and meta‐analysis11
The role of inflammation in the pathogenesis and treatment of arrhythmias11
A pharmacogenetic precision medicine approach to analgesia and sedation optimization in critically ill adults10
External evaluation of neonatal vancomycin population pharmacokinetic models: Moving from first‐order equations to Bayesian‐guided therapeutic monitoring10
Constructing a Personalized Treatment Rule for Initial Therapy in Early Parkinson's Disease10
Association between household opioid prescriptions and risk for overdose among family members not prescribed opioids10
Update on the clinical applications of SGLTis: Insight to benefits beyond hypoglycemic and cardiorenal protection10
Standards of practice to advance the quality of health care10
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Impact of medication intensification on 30‐day hospital readmissions in a geriatric trauma population: A multicenter cohort study10
Myocardial infarction associated with erenumab: A case report10
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Current clinical pharmacology issues in pregnancy and pediatrics9
Managing attention‐deficit/hyperactivity disorder in a breastfeeding mother: A case report9
Oral stepdown in Gram‐positive bloodstream infections: A step in the right direction9
Buprenorphine initiation strategies for opioid use disorder and pain management: A systematic review9
Cross‐titration from risperidone to clozapine utilizing clozapine serum concentrations: A case report9
Correction to “Comparative adherence trajectories of oral disease‐modifying agents in multiple sclerosis”9
Temporal shifts in safety and efficacy profile of mycophenolate mofetil 2 g versus 3 g daily early after heart transplantation9
Comment on “The power and pitfalls of underpowered studies”9
Response to comment on “Intravenous ketamine successfully treats treatment‐resistant catatonia in schizophrenia: A case report”9
Effect of proton pump inhibitors versus histamine‐2 receptor antagonists on acute kidney injury in septic patients at high risk for developing stress ulcers9
Evaluation of anti‐factor Xa concentrations using a body mass index‐based enoxaparin dosing protocol for venous thromboembolism prophylaxis in trauma patients9
Emerging therapies for eosinophilic esophagitis9
Precision‐based approaches to delirium in critical illness: A narrative review8
The efficacy and safety of sodium‐glucose cotransporter‐2 inhibitors in solid organ transplant recipients: A scoping review8
Aztreonam–avibactam: The dynamic duo against multidrug‐resistant gram‐negative pathogens8
Metformin use is associated with reduced acute kidney injury following coronary artery bypass grafting in patients with type 2 diabetes: An inverse probability of treatment weighting analysis8
Pharmacokinetic parameters over time during sepsis and the association of target attainment and outcomes in critically ill children and young adults receiving ceftriaxone8
Impact of pre‐lung transplant statin use on the development of primary graft dysfunction8
Serum potassium response to single‐dose sodium zirconium cyclosilicate for the treatment of asymptomatic hyperkalemia in hospitalized patients8
Assessment of a modified MINDS ‐based protocol for management of alcohol withdrawal syndrome on an inpatient medical service7
Genome‐wide associations with metabolic syndrome among UK Biobank participants reporting use of second‐generation antipsychotics7
Comment on “Tacrolimus in the treatment of childhood nephrotic syndrome: Machine learning detects novel biomarkers and predicts efficacy”7
Response to comment on “International consensus recommendations for the use of prolonged‐infusion β‐lactams endorsed by the American College of Clinical Pharmacy (ACCP), the British Society7
Population pharmacokinetics of linezolid and its major metabolites PNU‐142300 and PNU‐142586 in adult patients7
Vancomycin: An analysis and evaluation of eight population pharmacokinetic models for clinical application in general adult population7
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The MPRINT Hub Data, Model, Knowledge and Research Coordination Center: Bridging the gap in maternal–pediatric therapeutics research through data integration and pharmacometrics7
Use of naldemedine is associated with reduced incidence of hyperactive delirium in cancer patients with opioid‐induced constipation: A nationwide retrospective cohort study in Japan7
Association of Pneumonia, Fracture, Metabolic, and Renal Events With Long‐Term Proton Pump Inhibitor Use in Patients With Chronic Kidney Disease7
“Comment on ‘international consensus recommendations for the use of prolonged‐infusion β‐lactams endorsed by the American College of Clinical Pharmacy (ACCP), the British Society for Antimi7
The effect of antipsychotic treatment on hormonal, inflammatory, and metabolic biomarkers in healthy volunteers: A systematic review and meta‐analysis6
In Search of Big Beautiful Biomarkers6
Response to intravenous racemic ketamine after switch from intranasal (S)‐ketamine on symptoms of treatment‐resistant depression and post‐traumatic stress disorder in Veterans: A retrospective case se6
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Correction of posaconazole concentrations for hypoalbuminemia6
Tacrolimus in the treatment of childhood nephrotic syndrome: Machine learning detects novel biomarkers and predicts efficacy6
Clinical outcomes associated with anti‐Xa‐monitored enoxaparin for venous thromboembolism prophylaxis6
Steno‐sphere: Navigating the enigmatic world of emerging multidrug‐resistantStenotrophomonas maltophilia6
Biological Therapy and Small Molecules for Adults With Crohn's Disease: Systematic Review and Network Meta‐Analysis6
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Effect of cilostazol on preventing paclitaxel‐induced neuropathy in patients with breast cancer: A randomized controlled trial6
Evaluation of hyponatremia among older adults exposed to selective serotonin reuptake inhibitors and thiazide diuretics6
Cardiovascular adverse events in patients with hepatocellular carcinoma receiving vascular endothelial growth factor inhibitors6
Pharmacokinetics/pharmacodynamics analysis and establishment of optimal dosing regimens using unbound cefmetazole concentration for patients infected with Extended‐Spectrum β‐lactamase prod6
Retrospective cohort study of oral switch versus intravenous antibiotics for carbapenem‐resistant enterobacterales and Pseudomonas aeruginosa infections 6
Prevalence of prescription medication use that can exacerbate heart failure among US adults with heart failure6
Comparison of catheter‐related bloodstream infection rates in pediatric patients receiving parenteral nutrition with soybean oil‐based intravenous fat emulsion versus a mixed oil fat emulsion6
Transfer of antibiotics and their metabolites in human milk: Implications for infant health and microbiota6
Chloride dipstick to rapidly estimate urine sodium during diuresis in acute heart failure5
Response to Comment on “Proton Pump Inhibitor Concomitant Use to Prevent Oxaliplatin‐Induced Peripheral Neuropathy: Clinical Retrospective Cohort Study”5
Efficacy of adjuvant use of midodrine in patients with septic shock: An open label randomized controlled trial5
Increasing the bioavailability of oral esketamine by a single dose of cobicistat: A case study5
Poor tolerability of cystic fibrosis transmembrane conductance regulator modulator therapy in lung transplant recipients5
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Accelerated approval drug labels often lack information for clinical decision‐making5
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Simulated cost‐effectiveness of a novel precision‐guided dosing strategy in adult patients with Crohn's disease initiating infliximab maintenance therapy5
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Expert consensus recommendations for innovative antiretroviral drugs5
Impacts of age and BMI on vancomycin model choice in a Bayesian software: Lessons from a very large multi‐site retrospective study5
Comment on “Dosing implications for liposomal amphotericin B in pregnancy”5
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Examining the clinical impact of rapid multiplex polymerase chain reaction‐based diagnostic testing for bloodstream infections in a national cohort of the Veterans Health Administration5
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Intraperitoneal Granisetron for Post‐Laparoscopic Cholecystectomy Pain Management: A Double‐Blinded, Randomized Controlled Trial5
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Comparison of Bayesian‐derived and first‐order analytic equations for calculation of vancomycin area under the curve5
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Personalizing prevention: Advances in pharmacotherapy for HIV prevention4
Hereditary Pseudocholinesterase Deficiency and Succinylcholine: Historical Perspective, Therapeutic Implications, and Future Considerations4
Association of atrial fibrillation with lamotrigine: An observational cohort study4
International consensus recommendations for the use of prolonged‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy4
Risk of parkinsonism and related movement disorders with gabapentinoids or tramadol: A case‐crossover study4
Treatment of persistent methicillin‐susceptible Staphylococcus aureus bacteremia and presumed osteomyelitis with oxacillin and ertapenem in a premature neonate4
Precision medicine in the ICU: One size fits one patient4
Transplacental methadone exposure and risk of Neonatal Opioid Withdrawal Syndrome4
Adverse events with co‐prescription of angiotensin receptor blockers and clarithromycin compared to azithromycin: A population‐based retrospective cohort study4
PROK2, HRNR, and FIG4 as potential genetic biomarkers of high bleeding propensity in East Asian patients with acute coronary syndrome using ticagrelor4
ECLIPSES: Early initiation of sodium glucose cotransporter‐2 inhibitors for cardiovascular protection in patients with type 2 diabetes following acute coronary syndrom4
Association between mineralocorticoid receptor antagonists and kidney harm: A systematic review and meta‐analysis of randomized controlled trials4
The gray area of scientific adequacy4
Trends in the appropriateness of oral antibiotic prescriptions dispensed in the United States from 2010 to 20184
Contribution of pharmaceutical drugs of dependence to the incidence of neonatal abstinence syndrome in Western Australia between 2003 and 20184
Delirium event and associated treatment modifications among older adults with Alzheimer's disease: An interrupted time‐series analysis of Medicare data4
Safety and effectiveness of NMDA receptor antagonists for depression: A multidisciplinary review4
Thirty‐day risk of digoxin toxicity among older adults co‐prescribed trimethoprim‐sulfamethoxazole versus amoxicillin: A population‐based cohort study4
Randomized controlled trial to compare safety and efficacy of mycophenolate vs. cyclosporine after rituximab in children with steroid‐resistant nephrotic syndrome3
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Prescribing cascades in ambulatory care: A structured synthesis of evidence3
Efficacy and safety of mirikizumab compared with currently approved biologic drugs for the treatment of ulcerative colitis: A systematic review and network meta‐analysis3
Comparative effectiveness of sodium‐glucose cotransporter‐2 inhibitors among patients with heart failure with preserved ejection fraction3
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Pharmacogenomics and beyond! Customized pharmacotherapy for solid organ transplant recipients3
Developing precision‐based multidisciplinary pharmacotherapy management plans in the critically ill3
Comparative adherence trajectories of oral disease‐modifying agents in multiple sclerosis3
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GLP‐1RA‐induced delays in gastrointestinal motility: Predicted effects on coadministered drug absorption by PBPK analysis3
A systematic review of opioid use and multimodal strategies in solid organ transplant recipients and living donors3
Precision fluid and vasoactive drug therapy for critically ill patients3
Machine Learning Algorithms for Predicting Injurious Fall Risk Among Older Adults With Depression: A Prognostic Modeling Study3
Severe Persistent Urinary Retention Following Treatment With Intravenous Lecanemab3
A propensity score‐matching analysis of angiotensin‐converting enzyme inhibitor and angiotensin receptor blocker exposure on in‐hospital mortality in patients with acute respiratory failure3
Multicenter study evaluating target attainment of anti‐Factor Xa levels using various enoxaparin prophylactic dosing practices in adult trauma patients3
Correction to “Risk of incident antidepressant‐treated depression associated with use of 5α‐reductase inhibitors compared with use of α‐blockers in men with benign prostatic hyperplasia: A population‐3
Correction to “International consensus recommendations for the use of prolonged‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobi3
Response to comment on “Association of atrial fibrillation with lamotrigine: An observational cohort study”3
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Disease‐modifying therapies for amyloid transthyretin cardiomyopathy: Current and emerging medications3
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Reflections on the future of biomedical publishing3
Path of least recurrence: A systematic review and meta‐analysis of fidaxomicin versus vancomycin for Clostridioides difficile infection3
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Consensus recommendations for use of long‐acting antiretroviral medications in the treatment and prevention of HIV‐1: Endorsed by the American Academy of HIV Medicine, American College of C3
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Phase I study of the pharmacokinetics and safety of rezafungin in subjects with moderate/severe hepatic impairment and matched control subjects3
From bottle to bedside: Implementation considerations and antimicrobial stewardship considerations for bloodstream infection rapid diagnostic testing3
External Validation of the Fraser Equation for Estimation of Free Valproate Concentrations in Critically Ill Adults3
Risk of acute kidney injury in dapagliflozin users with type 2 diabetes: A nationwide propensity score‐matched cohort study in Korea2
Analysis of the frequency distribution of five single‐nucleotide polymorphisms of the MTRRgene in a Chinese pediatric population with acute lymphoblastic leukemia2
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Potential drug–drug interactions among U.S. adults treated with nirmatrelvir/ritonavir: A cross‐sectional study of the National Covid Cohort Collaborative (N3C)2
Maternal and neonatal outcomes associated with treating hypertension in pregnancy at different thresholds2
Using population pharmacokinetics to optimize initial vancomycin dosing guidelines for neonates to treat sepsis caused by coagulase‐negative staphylococcus2
Associations between antidepressant use patterns during pregnancy and birth outcomes among periconception antidepressant users2
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High‐Throughput Screening for Prescribing Cascades Among Real‐World Angiotensin‐ II Receptor Blockers ( ARBs 2
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Response to Comment on “Establishing discordance rate of estimated glomerular filtration rate between serum creatinine‐based calculations and cystatin‐C‐based calculations in critically ill patients”2
Evaluating the evidence for sacubitril/valsartan across the continuum of heart failure2
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Amoxicillin and penicillin G dosing in pediatric community‐acquired pneumococcal pneumonia in the era of conjugate pneumococcal vaccines2
Personalized antiseizure medication therapy in critically ill adult patients2
Direct oral to parenteral anticoagulant transitions: Role of factor Xa inhibitor‐specific anti‐Xa concentrations2
Intravenous Regular Insulin for Treatment of Hyperkalemia in Overweight Patients2
Impact of timing and dosing of four‐factor prothrombin complex concentrate administration on outcomes in warfarin‐associated intracranial hemorrhage2
Anticoagulation strategies in patients with extracorporeal membrane oxygenation: A network meta‐analysis and systematic review2
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Switching from intravenous vancomycin to oral antibiotics reduces adverse events in a retrospective cohort of outpatients with orthopedic infections2
Patient selection for mineralocorticoid receptor antagonists in heart failure with mildly reduced or preserved ejection fraction2
Enhancing thromboprophylaxis after colorectal cancer surgery in China: Bridging the gap between evidence and implementation through pathway optimization2
Belzutifan's role in the treatment landscape of clear cell renal cell carcinoma2
Updates in pulmonary drug‐resistant tuberculosis pharmacotherapy: A focus on BPaL and BPaLM2
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Comment on “Delirium event and associated treatment modifications among older adults with Alzheimer's disease: An interrupted time‐series analysis of Medicare data”2
Systematic review of drug–drug interactions between rifamycins and anticoagulant and antiplatelet agents and considerations for management2
Theophylline for the management of respiratory disorders in adults in the 21st century: A scoping review from the American College of Clinical Pharmacy Pulmonary Practice and Research Network2
Correction to Chloride Dipstick to Rapidly Estimate Urine Sodium During Diuresis in Acute Heart Failure2
Transdermal rivastigmine as a therapeutic option in severe diphenhydramine‐induced anticholinergic toxicity: A case report and literature review2
Prescription Sequence Symmetry Analysis for Detection of Chronic Opioid Use Adverse Event Signals Using Administrative Claims Data1
High prescribing of antibiotics is associated with high prescribing of opioids in medical and dental providers1
The Use of Plasma Exchange for Clozapine Intoxication: A Case Report1
Precision Daptomycin Dosing: Comparison of 3‐, 2‐, 1‐, and 0‐Concentration Sample Strategies1
Albuminuria‐based stratification of end‐stage kidney disease progression and mortality with sodium‐glucose cotransporter 2 inhibitors (SGLT2i): A retrospective cohort study in type 2 diabet1
Is ketamine infusion effective and safe as an adjuvant of sedation in the PICU? Results from the Ketamine Infusion Sedation Study (KISS)1
Evaluation of methotrexate Pharmacogenomic variation to predict acute neurotoxicity in children with acute lymphoblastic leukemia1
Review of anticoagulation considerations in extracorporeal membrane oxygenation support1
Drug–Drug Interactions and Combination Therapy Strategies of Amiodarone With Digoxin, Rivaroxaban, and Phenytoin Assessed by Physiologically Based Pharmacokinetic Modeling1
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Association of Omeprazole‐Related Myopathy With Drug–Drug and Drug–Gene Interactions Involving CYP2C19 and CYP3A4: A Nested Case–Control Study1
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