Regulatory Toxicology and Pharmacology

Papers
(The H4-Index of Regulatory Toxicology and Pharmacology is 29. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Perspectives on the elimination of animal assays in the assessment of carcinogenicity104
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats77
Target organ toxicity in Sprague Dawley rats following oral exposure to complex groundwater mixture: Assessment of dose-response relationships using histopathological and biochemical alterations75
Ames mutagenicity of 15 aryl, benzyl, and aliphatic ring N-nitrosamines74
Controlling cleaning agent residues in pharmaceutical manufacturing: A harmonized scientific strategy74
HESI GTTC ring trial: Concordance between Ames and rodent carcinogenicity outcomes for N-nitrosamines (NAs) with rat and hamster metabolic conditions70
Prevalence and sample sizes in pre-clinical studies63
Ability of mathematical models to predict human in vivo percutaneous penetration of steroids62
Selectively addressing total risk avoidance for certain chemicals while overlooking others: The case of per-and-poly-fluoroalkyls59
A Cautionary tale for using read-across for cancer hazard classification: Case study of isoeugenol and methyl eugenol54
Two-year carcinogenicity study of a novel plasticizer, bis(2-ethylhexyl) cyclohexane-1,4-dicarboxylate (Eco-DEHCH), by oral diet in Han Wistar rats53
Preclinical safety evaluation of the ethanolic extract from the aerial parts of Gomphrena celosioides Mart. in rodents52
Control of N-nitrosamine impurities in drug products: Progressing the current CPCA framework and supporting the derivation of robust compound specific acceptable intakes51
Acceptable intakes (AIs) for 11 small molecule N-nitrosamines (NAs)50
Is periventricular heterotopia a useful endpoint for developmental thyroid hormone system disruption in mouse toxicity studies?47
Assessing biological oxidative damage induced by graphene-based materials: An asset for grouping approaches using the FRAS assay46
Editorial Board45
Editorial Board42
A tool to support food substance safety evaluations in the United States41
Nonclinical safety assessment of engineered T cell therapies39
Exploring the potential of ToxCast™ data for mechanism-based prioritization of chemicals in regulatory context: Case study with priority existing chemicals (PECs) under K-REACH36
Incorporating Singaporean habits and practices for cosmetics and personal care products into a global consumer aggregate exposure model35
Results from two-year rodent oral carcinogenicity studies of cizolirtine, a substance-P and calcitonin gene-related peptide release modulator34
Editorial: 2024 - A promising start for regulatory toxicology and pharmacology33
Acute dose toxicity evaluation of the food supplement calcium 3-hydroxy-3-methylbutyrate (HMB) in female Sprague Dawley rats33
Apparent Khat chewers exposure to DDT in Ethiopia and its potential toxic effects: A scoping review32
Importance of tailored non-clinical safety testing of novel antimalarial drugs: Industry best-practice32
False positive findings associated with adenoviral vector-based vaccine underscore the regulatory necessity to eliminate abnormal toxicity test30
Decision making in next generation risk assessment for skin allergy: Using historical clinical experience to benchmark risk29
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