OOIR: Observatory of International Research

Papers

(The H4-Index of Regulatory Toxicology and Pharmacology is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Perspectives on the elimination of animal assays in the assessment of carcinogenicity	197
Evaluation of the OECD QSAR toolbox automatic workflow for the prediction of the acute toxicity of organic chemicals to fathead minnow	80
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats	68
Ames mutagenicity of 15 aryl, benzyl, and aliphatic ring N-nitrosamines	64
Target organ toxicity in Sprague Dawley rats following oral exposure to complex groundwater mixture: Assessment of dose-response relationships using histopathological and biochemical alterations	62
Qualitative analysis of actual Standard for Exchange of Nonclinical Data (SEND) datasets for Data Domains: Proposition from Japan Pharmaceutical Manufacturers Association SEND Taskforce Team on standa	60
Comprehensive investigation evaluating the carcinogenic hazard potential of acetaminophen	56
Ability of mathematical models to predict human in vivo percutaneous penetration of steroids	52
Selectively addressing total risk avoidance for certain chemicals while overlooking others: The case of per-and-poly-fluoroalkyls	50
Preclinical safety evaluation of the ethanolic extract from the aerial parts of Gomphrena celosioides Mart. in rodents	49
Controlling cleaning agent residues in pharmaceutical manufacturing: A harmonized scientific strategy	46
Assessing biological oxidative damage induced by graphene-based materials: An asset for grouping approaches using the FRAS assay	43
Control of N-nitrosamine impurities in drug products: Progressing the current CPCA framework and supporting the derivation of robust compound specific acceptable intakes	43
Twenty six-week repeat dose oral rat toxicity study of cizolirtine, a substance-P and calcitonin gene-related peptide release modulator	38
Two-year carcinogenicity study of a novel plasticizer, bis(2-ethylhexyl) cyclohexane-1,4-dicarboxylate (Eco-DEHCH), by oral diet in Han Wistar rats	38
Is periventricular heterotopia a useful endpoint for developmental thyroid hormone system disruption in mouse toxicity studies?	38
A Cautionary tale for using read-across for cancer hazard classification: Case study of isoeugenol and methyl eugenol	37
Acceptable intakes (AIs) for 11 small molecule N-nitrosamines (NAs)	37
HESI GTTC Ring Trial: Concordance between Ames and Rodent Carcinogenicity Outcomes for N-Nitrosamines (NAs) with Rat and Hamster Metabolic Conditions	37
Nonclinical safety assessment of engineered T cell therapies	37
Exploring the potential of ToxCast™ data for mechanism-based prioritization of chemicals in regulatory context: Case study with priority existing chemicals (PECs) under K-REACH	36
Scientific considerations in the regulatory approval of generic (or biosimilar) version of enoxaparin sodium – A lifesaving carbohydrate polymer	34
Derivation of an occupational exposure limit for β-glucans	33
Editorial Board	31
Editorial Board	28

False positive findings associated with adenoviral vector-based vaccine underscore the regulatory necessity to eliminate abnormal toxicity test	28
Apparent Khat chewers exposure to DDT in Ethiopia and its potential toxic effects: A scoping review	28
Decision making in next generation risk assessment for skin allergy: Using historical clinical experience to benchmark risk	27
Subchronic oral toxicity study of rhubarb extract in Sprague-Dawley rats	27