OOIR: Observatory of International Research

Papers

(The median citation count of Seminars in Liver Disease is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Critical Care Management of Acute-on-Chronic Liver Failure: Certainties and Unknowns	82
Liver Immunology, Immunotherapy, and Liver Cancers: Time for a Rethink?	42
A Precision Medicine Guided Approach to the Utilization of Biomarkers in MASLD	33
Hepatic Extracellular Matrix and Its Role in the Regulation of Liver Phenotype	33
Tight Junction Proteins as Therapeutic Targets to Treat Liver Fibrosis and Hepatocellular Carcinoma	32
Patient-Reported Outcomes in Metabolic Dysfunction-Associated Steatotic Liver Disease	27
HBV Biomarkers and Their Role in Guiding Treatment Decisions	26
Tailored Model of Care for Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease	25
Genetic and Epigenetic Basis of Drug-Induced Liver Injury	24
Emerging Targets for the Treatment of Primary Sclerosing Cholangitis	23
Growth Hormone Signaling in Liver Diseases: Therapeutic Potentials and Controversies	18
Genetic Contributions to Biliary Atresia: A Developmental Cholangiopathy	18
Alcohol Plus Additional Risk Factors: Rodent Model of Liver Injury	17
Role of YAP1 Signaling in Biliary Development, Repair, and Disease	16
Mice Engrafted with Human Liver Cells	16
Wilson Disease: Novel Diagnostic and Therapeutic Approaches	16
Dietary Recommendations for the Management of Non-alcoholic Fatty Liver Disease (NAFLD): A Nutritional Geometry Perspective	14
Physiomimetic In Vitro Human Models for Viral Infection in the Liver	14
Diagnosis and Management of Early Stages of ALD	13
A Global Systematic Review of Hepatitis C Elimination Efforts through Micro-Elimination	12
Circadian Regulation of Gene Expression and Metabolism in the Liver	11
	11
Role of Intestinal Barrier Disruption to Acute-on-Chronic Liver Failure	10
To TIPS or Not to TIPS in High Risk of Variceal Rebleeding and Acute-on-Chronic Liver Failure	10
Liver Neurobiology: Regulation of Liver Functions by the Nervous System	10

Patient-Centered Treatment of Cirrhosis	9
Role of Complement in Liver Diseases	9
	9
Primary Cilia in Hepatic Biliary Hyperplasia: Implications for Liver Diseases	9
Novel Biomarkers of AKI in Cirrhosis	8
Hepatitis Delta Infection: A Clinical Review	8
Management of Portal vein Thrombosis in Cirrhosis	8
Endoscopic Advances in Hepatology	8
Mesenchymal Stem Cell Transplantation in Liver Diseases	8
Liver Transplantation for Hepatocellular Carcinoma: A Narrative Review and A Glimpse into The Future	8
This Is What Metabolic Dysfunction–Associated Steatotic Liver Disease Looks Like: Potential of a Multiparametric MRI Protocol	8
Hepatocellular Carcinoma Chemoprevention with Generic Agents	8
Combined hepatocellular-cholangiocarcinoma: a clinical and molecular review	8
	8
The Hepatic Porphyrias: Revealing the Complexities of a Rare Disease	7
Big Data Analytics in Large Cohorts: Opportunities and Challenges for Research in Hepatology	7
Erratum to: Genetic Contributions to Biliary Atresia: A Developmental Cholangiopathy	7
Noninvasive Tests to Assess Fibrosis and Disease Severity in Metabolic Dysfunction-Associated Steatotic Liver Disease	7
Metabolic Injury of Hepatocytes Promotes Progression of NAFLD and AALD	7
LncRNAs, RNA Therapeutics, and Emerging Technologies in Liver Pathobiology	7
Pediatric and Adult Liver Disease in Alpha-1 Antitrypsin Deficiency	7
Extracellular Vesicles and Micro-RNAs in Liver Disease	7
Unraveling the Complexities of Immune Checkpoint Inhibitors in Hepatocellular Carcinoma	6
Research Progress on the Role and Mechanism of IL-37 in Liver Diseases	6
Advancements in MELD Score and Its Impact on Hepatology	6
Erratum to: Scavenger Receptors: Novel Roles in the Pathogenesis of Liver Inflammation and Cancer	6
Nonalcoholic Fatty Liver Disease: Current Global Burden	6
Shared Mechanisms between Cardiovascular Disease and NAFLD	6
Is There a Safe Alcohol Consumption Limit for the General Population and in Patients with Liver Disease?	6
Screening for At-Risk Nonalcoholic Fatty Liver Disease in the Primary Care Setting	6
Hepatic Innervations and Nonalcoholic Fatty Liver Disease	5
	5
	5
Understanding Hepatic Porphyrias: Symptoms, Treatments, and Unmet Needs	5
The Ways to Die: Cell Death in Liver Pathophysiology	5
Gestational and Developmental Contributors of Pediatric MASLD	5
Alcohol-Metabolizing Enzymes, Liver Diseases and Cancer	5
Influence of Sex in the Development of Liver Diseases	5
	4
Role of Hepatocyte Nuclear Factor 4 Alpha in Liver Cancer	4
Understanding and Treating Hepatorenal Syndrome: Insights from Recent Research	4
	4
Angiocrine Signaling in Sinusoidal Health and Disease	4
Mastering Core Recommendations during HEPAtology ROUNDS in Patients with Advanced Chronic Liver Disease	4
Pathogenesis and Management of Intestinal Failure-Associated Liver Disease	4
	4
Therapeutic Potential of Nutraceuticals against Drug-Induced Liver Injury	4
The Ploidy State as a Determinant of Hepatocyte Proliferation	4
Immune Checkpoint Inhibitor-Induced Liver Injury	4
Role of Neutrophils in the Development of Steatotic Liver Disease	4

Treating Alcohol Use Disorder in Patients with Alcohol-Associated Liver Disease: Controversies in Pharmacological Therapy	4
Novel Endoscopic Bariatric Therapies for the Management of Nonalcoholic Steatohepatitis	4
MetALD: Genetic Factors and Clinical Outcomes	4
The Molecular Pathogenesis of Sarcopenia/Frailty in Cirrhosis	3
UDCA for Drug-Induced Liver Disease: Clinical and Pathophysiological Basis	3
Integrated Alcohol Use Disorder and Liver Disease Management	3
Microbial Modulation of the Gut–Liver Axis in Autoimmune Liver Diseases	3
	3
Preface (Introduction): Metabolic Liver Disease: A New Era in Hepatology	3
Beyond Varices: Complications of Cirrhotic Portal Hypertension in Pediatrics	3
Early Diagnosis and Prevention of Infections in Cirrhosis	3
Animal Models of Porphyria with Hepatic Involvement	3
Current Challenges and Future Direction in Surveillance for Hepatocellular Carcinoma in Patients with Nonalcoholic Fatty Liver Disease	3
NAFLD in Cardiovascular Diseases: A Contributor or Comorbidity?	3
The Neglected Role of Bile Duct Epithelial Cells in NASH	3
Inflammation in Steatotic Liver Diseases: Pathogenesis and Therapeutic Targets	3