Drug Development Research

Article	Citations
RETRACTION: “Dose‐dependent Chemopreventive Effects of Citronellol in DMBA‐Induced Breast Cancer Among Rats”	64
Imaging of bacterial infection: Harnessing positron emission tomography and Cherenkov luminescence imaging with UBI‐derived octapeptide	57
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CQMUH‐011 mitigates autoimmune hepatitis via inhibiting the function of T lymphocytes	49
Knockdown of IGF2BP3 inhibits the tumorigenesis of gallbladder cancer and modifies tumor microenvironment	42
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Terbutaline attenuates LPS ‐induced injury of pulmonary microvascular endothelial cells by cAMP /Epac signaling	29
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Synthesis and characterization of new pyrazole–tetrazole derivatives as new vasorelaxant agents	28
Loganin exerts a protective effect on ischemia–reperfusion‐induced acute kidney injury by regulating JAK2/STAT3 and Nrf2/HO‐1 signaling pathways	25
CircRNF121 knockdown suppresses the progression of cervical cancer by regulating miR ‐153‐3p/ ATF2 axis and	25
9‐Ethynyl noscapine induces G2 /M arrest and apoptosis by disrupting tubulin polymerization in cervical cancer	23
Naringenin inhibits autophagy and epithelial‐mesenchymal transition of human lens epithelial cells by regulating the Smad2/3 pathway	22
Redox‐responsive glycosylated combretastatin A‐4 derivative as novel tubulin polymerization inhibitor for glioma and drug delivery	22
Potential of nafimidone derivatives against co‐morbidities of epilepsy: In vitro, in vivo, and in silico investigations	21
Bioinformatics Exploration of the Therapeutic Potential of Lotus Seed Compounds in Multiple Sclerosis: A Network Analysis of c‐Jun Pathway	21
Reviewing on AI‐Designed Antibiotic Targeting Drug‐Resistant Superbugs by Emphasizing Mechanisms of Action	21
Investigating the Impact of B Cell‐Related Genes on Colorectal Cancer Immunosuppressive Environment and Immunotherapy Evasion	21
TSPAN1 silencing protects against cerulein‐induced pancreatic acinar cell injury via targeting AGR2	20
Contribution of N‐heterocycles towards anti‐tubercular drug discovery (2014–2019); predicted and reengineered molecular frameworks	19
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Targeting TRAF3IP2 alleviates high glucose‐induced cardiomyocyte inflammation and apoptosis	19
Circ_0001667 knockdown blocks cancer progression and attenuates adriamycin resistance by depleting NCOA3 via releasing miR‐4458 in breast cancer	18

Pantoprazole suppresses carcinogenesis and growth of hepatocellular carcinoma by inhibiting glycolysis and Na+/H+ exchange	18
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Parecoxib ameliorates renal toxicity and injury in sepsis‐induced mouse model and LPS ‐induced HK ‐2 cells	17
Synthesis and evaluation of 2‐(4‐[4‐acetylpiperazine‐1‐carbonyl] phenyl)‐1H‐benzo[d]imidazole‐4‐carboxamide derivatives as potential PARP‐1 inhibitors and preliminary study on st	16
Structural Diversity and Mutational Challenges of Toll‐Like Receptor 4 Antagonists as Inflammatory Pathway Blocker	16
Estradiol reduces ACE2 and TMPRSS2 mRNA levels in A549 human lung epithelial cells	16
Astragaloside IV enhances the sensibility of lung adenocarcinoma cells to bevacizumab by inhibiting autophagy	16
A thiourea‐bridged 99mTc(CO)3‐dipicolylamine‐2‐nitroimidazole complex for targeting tumor hypoxia: Utilizing metabolizable thiourea‐bridge to improve pharmacokinetics	16
Thrombospondin‐1 mimic peptide PKHB1 induced endoplasmic reticulum stress‐mediated but CD47‐independent apoptosis in non‐small cell lung cancer	15
Trifolirhizin targets PTK6 to induce autophagy and exerts antitumor effects in nasopharyngeal carcinoma	15
α‐Pinene inhibits the growth of cervical cancer cells through its proapoptotic activity by regulating the miR‐34a‐5p/Bcl‐2 signaling axis	15
Research Progress of Endoplasmic Reticulum Targeting Metal Complexes in Cancer Therapy	15
Anxiolytic Effect of Sesamol, Possibly Through the GABAkine Interaction Pathway	15
Comprehensive characterization and preclinical assessment of an imidazopyridine‐based anticancer lead molecule	14
The Role of Fatty Acid Metabolism, the Related Potential Biomarkers, and Targeted Therapeutic Strategies in Gastrointestinal Cancers	14
Pyridazine derivatives as selective COX‐2 inhibitors: A review on recent updates	14
Antitumor activity of galaxamide involved in cell apoptosis and stemness by inhibiting Wnt/β‐catenin pathway in cervical cancer	14
New insights into the anticancer therapeutic potential of icaritin and its synthetic derivatives	13
New S‐substituted‐3‐phenyltetrahydrobenzo[4,5]thieno[2,3‐d]pyrimidin‐4(3H)‐one scaffold with promising anticancer activity profile through the regulation and inhibition of mutated	13
Tetrahydropalmatine induces the polarization of M1 macrophages to M2 to relieve limb ischemia‐reperfusion‐induced lung injury via inhibiting the TLR4/NF‐κB/NLRP3 signaling pathway	13
Novel matrinic acid derivatives bearing 2‐anilinothiazole structure for non‐small cell lung cancer treatment with improved Hsp90 targeting effect	13
Antiplasmodial action of 4‐nitrobenzenesulfonamide chalcones: Design, synthesis, characterisation, in vitro and in silico evaluation against blood stages of Plasmodium falciparum 3D7	13
Peimine‐induced apoptosis and inhibition of migration by regulating reactive oxygen species‐mediated MAPK/STAT3/NF‐κB and Wnt/β‐catenin signaling pathways in gastric cancer MKN‐45 cells	13
Synthesis and investigation of the cholinesterase inhibitory and antioxidant capacities of some novel N'‐(quinolin‐4‐ylmethylene)propanehydrazides against Alzheimer's disease	13
Quercetin ameliorates salivary gland apoptosis and inflammation in primary Sjögren's syndrome through regulation of the leptin/OB‐R signaling	13
Tirbanibulin (KX2‐391) analog KX2‐361 inhibits botulinum neurotoxin serotype A mediated SNAP‐25 cleavage in pre‐ and post‐intoxication models in cells	13
Design, synthesis of novel chromene‐based scaffolds targeting hepatocellular carcinoma: Cell cycle arrest, cytotoxic effect against resistant cancer cells, apoptosis induction, and c‐Src inhibition	12
Repurposing of digoxin in pain and inflammation: An evidence‐based study	12
Evaluation of geranylgeranyl diphosphate synthase inhibition as a novel strategy for the treatment of osteosarcoma and Ewing sarcoma	12
Anti‐inflammatory effect and mechanism of catalpol in various inflammatory diseases	12
Coumarin derivatives with potential anticancer and antibacterial activity: Design, synthesis, VEGFR‐2 and DNA gyrase inhibition, and in silico studies	12
Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment	12
Neutrophil hitchhiking: Riding the drug delivery wave to treat diseases	12
Identification of potential targets against SARS‐CoV‐2 of antiviral drugs based on photoaffinity probes	11
A growth‐based assay using fluorescent protein emission to screen for S‐adenosylmethionine synthetase inhibitors	11
Sulfamethizole Attenuates Pentylenetetrazole‐Induced Seizures in Mice via mTOR Inhibition	11
The HSP90 inhibitor 17‐AAG induced calcium‐mediated apoptosis in filarial parasites	11
Design, synthesis, in vitro, and in vivo evaluation of novel phthalazinone‐based derivatives as promising acetylcholinesterase inhibitors for treatment of Alzheimer's disease	11
The transcription factor ATF2 promotes gastric cancer progression by activating the METTL3/cyclin D1 pathway	11
An appraisal of anticancer activity with structure–activity relationship of quinazoline and quinazolinone analogues through EGFR and VEGFR inhibition: A review	11
Cinepazide maleate promotes recovery from spinal cord injury by inhibiting inflammation and prolonging neuronal survival	11
Berberine attenuates inflammation and oxidative stress and modulates lymphocyte E‐NTPDase in acute hyperlipidemia	11
Explore new quinoxaline pharmacophore tethered sulfonamide fragments as in vitro α‐glucosidase, α‐amylase, and acetylcholinesterase inhibitors with ADMET and molecular modeling simulation	11
A liposomal radionanoformulation for targeted drug delivery and real time monitoring by radionuclide imaging for HER2 overexpressing cancers	11
Safety study of topical naltrexone therapy for diabetic skin wounds is confirmed in Göttingen mini‐pigs	10
Comparative pharmacodynamic and pharmacokinetic study of MIDD0301 and its (S) enantiomer	10
Therapeutic potential and research progress of diosgenin for lipid metabolism diseases	10
Susceptibility of Leishmania to novel pentavalent organometallics: Investigating impact on DNA and membrane integrity in antimony(III)‐sensitive and ‐resistant strains	10
Downregulation of HIGD1B induces mitochondria‐mediated apoptosis in gastric cancer cells by inactivating Akt and ERK pathways	10

Multitargeted C9‐substituted ester and ether derivatives of berberrubine for Alzheimer's disease: Design, synthesis, biological evaluation, metabolic stability, and pharmacokinetics	10
2‐(Methyl(phenyl)amino)‐N‐(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition	10
Schisandrin B ameliorates non‐alcoholic liver disease through anti‐inflammation activation in diabetic mice	9
Effects of toluidine blue O and methylene blue on growth and viability of pancreatic cancer cells	9
Design and synthesis of novel tetrabromophthalimide derivatives as potential tubulin inhibitors endowed with apoptotic induction for cancer treatment	9
Recent research brings hope for reshaping the co‐evolutionary arms race against parasitic infectious diseases	9
New chromanone derivatives containing thiazoles: Synthesis and antitumor activity evaluation on A549 lung cancer cell line	9
d‐Galactose treatment increasesACE2,TMPRSS2, andFURINand reducesSERPINA1mRNAexpression inA549human lung ep	9
Discovery of pyrazole‐1‐carboxamide derivatives as novel Gi‐biased μ‐opioid receptor agonists	9
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Discovery of novel indole‐1,2,4‐triazole derivatives as tubulin polymerization inhibitors	9
Indole‐based aryl sulfides target the cell wall of Staphylococcus aureus without detectable resistance	9
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A cytotoxic survey on 2‐amino‐1H‐imidazol based synthetic marine sponge alkaloid analogues	9
Structure and activity of ananti‐epidermal growth factor receptor antibody without galactose‐α‐1,3‐galactose residues	9
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Benzoxazolone‐arylpiperazinyl scaffold‐based PET ligand for 5‐HT7: Synthesis and biological evaluation	9
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Changes in the proportions of an active pharmaceutical through cocrystals	9
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Comprehensive investigations for a potential natural prophylaxis—A cellular and murine model for apple cider vinegar against hydrogen peroxide and scopolamine induced oxidative stress	8
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Design, Synthesis and Molecular Docking of New Thieno[2,3‑d]Pyrimidin‐4‐One Derivatives as Dual EGFR and FGFR Inhibitors	8
Anlotinib improves bile duct ligature‐induced liver fibrosis in rats via antiangiogenesis regulated by VEGFR2/mTOR pathway	8
Autophagic and apoptotic cell death induced by the quinoline derivative 2‐(6‐methoxynaphthalen‐2‐yl)quinolin‐4‐amine in pancreatic cancer cells is via ER stress and inhibition of Akt/m	8
Augmented antiviral T cell immunity by oral administration of IMM‐124E in preclinical models and a phase I/ IIa clinical trial: A	8
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CircMYBL2 regulates the resistance of cervical cancer cells to paclitaxel via miR‐665‐dependent regulation of EGFR	8
New isolate from Salvinia molesta with antioxidant and urease inhibitory activity	8
Medicinal chemistry of pyrophosphate mimics: A mini review	8
Azithromycin inhibited oxidative stress and apoptosis of high glucose‐induced podocytes by inhibiting STAT1 pathway	8
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Potential antiviral activity of isorhamnetin against SARS‐CoV‐2 spike pseudotyped virus in vitro	8
N‐Substituted piperazine‐coupled imidazo[2,1‐b]thiazoles as inhibitors of Mycobacterium tuberculosis: Synthesis, evaluation, and docking studies	8
Design and synthesis of vancomycin‐functionalized ZnFe2O4 nanoparticles as an effective antibacterial agent against methicillin‐resistant Staphylococcus aureus	8
Repurposing of FDA‐approved drugs as inhibitors of sterol C‐24 methyltransferase of Leishmania donovani to fight against leishmaniasis	8
Fraxetin exerts anticancer effect in glioma by suppressing MiR‐21‐3p	8
Papaverine, a promising therapeutic agent for the treatment of COVID‐19 patients with underlying cardiovascular diseases (CVDs)	7
Cover Image, Volume 85, Issue 1	7
Induction of apoptosis by oridonin in nonfunctioning pituitary adenoma cells	7
Cellular and molecular mechanisms involved in the analgesic effects of botulinum neurotoxin: A literature review	7
T‐17, a novel cyclin‐dependent kinases/histone deacetylases dual inhibitor, induces cancer cells death through cell cycle arrest and apoptosis	7
Pyridazine and pyridazinone derivatives: Synthesis and in vitro investigation of their anti‐inflammatory potential in LPS‐induced RAW264.7 macrophages	7
Design, synthesis, in silico, and in vitro evaluation of novel benzyloxybenzene substituted (S)‐α‐amino amide derivatives as cholinesterases and monoaminoxidases inhibitor	7
Icariside II suppresses the tumorigenesis and development of ovarian cancer by regulating miR‐144‐3p/IGF2R axis	7
The cytotoxicity of karanjin toward breast cancer cells is involved in the PI3K/Akt signaling pathway	7
Synthesis, characterization, molecular modeling studies, and biological evaluation of metal piroxicam complexes (M = Ni(II), Pt(IV), Pd(II), Ag(I)) as antibacterial and anticancer agents	7
RecQ protein‐like 4 drives cisplatin chemosensitivity of cervical cancer cells by modulating annexin A2	7
The role and advance of ubiquitination and deubiquitination in depression pathogenesis and treatment	7
Design, synthesis, and evaluation of novel Indole‐Based small molecules as sirtuin inhibitors with anticancer activities	6
Knockdown of replication protein A 3 induces protective autophagy and enhances cisplatin sensitivity in lung adenocarcinoma by inhibiting AKT/mTOR signaling via binding to cyclin‐dependent kinases reg	6
Synthesis and anti‐HIV activity of non‐nucleoside reverse‐transcriptase inhibitor DB02 phosphate derivatives based on water‐soluble optimization	6
Xanthatin induce DDP‐resistance lung cancer cells apoptosis through regulation of GLUT1 mediated ROS accumulation	6
Design of novel broad‐spectrum antiviral nucleoside analogues using natural bases ring‐opening strategy	6
Novel insights on [1,2]oxazolo[5,4‐e]isoindoles on multidrug resistant acute myeloid leukemia cell line	6
Fasudil attenuates syncytin‐1‐mediated activation of microglia and impairments of motor neurons and motor function in mice	6
Higher ATM expression in lymphoblastoid cell lines from centenarian compared with younger women	6
Network pharmacology analysis and experimental verification of the antitumor effect and molecular mechanism of isocryptomerin on HepG2 cells	6
Two new alkaloids from Dendrobium nobile Lindl. exhibited neuroprotective activity, and dendrobine alleviated Aβ1−42‐induced apoptosis by inhibiting CDK5 activation in PC12 cells	6
AEBP1 Silencing Protects Against Cerebral Ischemia/Reperfusion Injury by Regulating Neuron Ferroptosis and Microglia M2 Polarization Through PRKCA‐PI3K‐Akt Axis	6
PX‐12 synergistically enhances the therapeutic efficacy of vorinostat under hypoxic tumor microenvironment in oral squamous cell carcinoma in vitro	6
AS602801 treatment suppresses breast cancer metastasis to the brain by interfering with gap‐junction communication by regulating Cx43 expression	6
Biphenylsulfonamides as effective MMP‐2 inhibitors with promising antileukemic efficacy: Synthesis, in vitro biological evaluation, molecular docking, and MD simulation analysis	6
Discovery of 4‐(4‐aminophenyl)‐6‐phenylisoxazolo[3,4‐b]pyridine‐3‐amine derivatives as novel FLT3 covalent inhibitors for the intervention of acute myeloid leukemia	6
A novel cinnamic and caffeic acid‐conjugated peptide analogs with anticonvulsant and analgesic potency: Comparative analyses of trans/cis isomers	6
Asiaticoside enhances the effect of propofol on the invasion, ferroptosis and immune escape of bladder cancer	6
Identification of ROS and KEAP1‐related genes and verified targets of α‐hederin induce cell death for CRC	6
The recent development of thymol derivative as a promising pharmacological scaffold	5
Secoisolariciresinol diglucoside induces pyroptosis by activating caspase‐1 to cleave GSDMD in colorectal cancer cells	5
Design, synthesis, and bioactivity evaluation of clindamycin derivatives against multidrug‐resistant bacterial strains	5
Circ‐OPHN1 suppresses the proliferation, migration, and invasion of trophoblast cells through mediating miR‐558/THBS2 axis	5
Synthesis of tricyclic and tetracyclic benzo[6,7]cycloheptane derivatives linked morpholine moiety as CDK2 inhibitors	5
YTHDF2 interference suppresses the EMT of cervical cancer cells and enhances cisplatin chemosensitivity by regulating AXIN1	5
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New pyrrole derivatives as DNA gyrase and 14α‐demethylase inhibitors: Design, synthesis, antimicrobial evaluation, and molecular docking	5
Enriching iPSC research diversity: Harnessing human biobank collections for improved ethnic representation	5
Propofol promotes migration, alleviates inflammation, and apoptosis of lipopolysaccharide‐induced human pulmonary microvascular endothelial cells by activating PI3K/AKT signaling	5
A new perspective on antiangiogenic antibody drug resistance: Biomarkers, mechanisms, and strategies in malignancies	5

Diphenyl urea‐benzylidene acetohydrazide hybrids as fibroblast growth factor receptor 1 inhibitors and anticancer agents	5
MLLT3 knockdown suppresses proliferation and cell mobility in human lung adenocarcinoma	5
Ricolinostat suppresses proliferation, promotes apoptosis, and enhances the antiproliferative activity of topoisomerase inhibitors in cervical cancer cells	5
New Dichalcogenides Induce Oxidative Stress and Cell Death of Leishmania amazonensis	5
Does Metabolic Manager Show Encouraging Outcomes in Alzheimer's?: Challenges and Opportunity for Protein Tyrosine Phosphatase 1b Inhibitors	5
Mitoquinone intravitreal injection ameliorates retinal ischemia–reperfusion injury in rats involvingSIRT1/Notch1/NADPHaxis	5
Phthalimide as a versatile pharmacophore scaffold: Unlocking its diverse biological activities	5
Verbascoside enhances radiosensitivity of hepatocellular carcinoma cells through regulating miR‐101‐3p/Wee1 axis	5
Reduction‐Responsive RGD‐Docetaxel Conjugate: Synthesis, In Vitro Drug Release and In Vitro Antitumor Activity	5
YTHDF2 promotes gastric cancer progression and enhances chemoradiotherapy resistance	5
A novel thieno[2,3‐d]pyrimidine derivative inhibiting vascular endothelial growth factor receptor‐2: A story of computer‐aided drug discovery	5
Noscapine modulates hypoxia‐induced angiogenesis and hemodynamics: Insights from a zebrafish model investigation	5
Discovery of Novel SIRT3 Inhibitors for the Cancer Differentiation Therapy by Structural Modification	5
TRPM2‐AS promotes paclitaxel resistance in prostate cancer by regulating FOXK1 via sponging miR‐497‐5p	5
Recent advancement in drug development of nitro(NO2)‐heterocyclic compounds as lead scaffolds for the treatment of Mycobacterium tuberculosis	5
Chrysin modulates protein kinase IKKε/TBK1, insulin sensitivity and hepatic fatty infiltration in diet‐induced obese mice	4
PDE4 inhibitor Roflumilast modulates inflammation and lipid accumulation in PCOS mice to improve ovarian function and reduce DHEA‐induced granulosa cell apoptosis in vitro	4
Ginsenoside CK Promotes Cell Apoptosis via Regulating P53 Signal Pathway in Non‐Small Cell Lung Cancer	4
Recombinant human epidermal growth factor‐loaded liposomes and transferosomes for dermal delivery: Development, characterization, and cytotoxicity evaluation	4
Discovery of Hydrazine Clubbed Thiazoles as Potential Antidiabetic Agents: Synthesis, Biological Evaluation, and Molecular Docking Studies	4
Design and synthesis of novel hexahydrobenzo[4,5]thieno[2,3‐d]pyrimidine derivatives as potential anticancer agents with antiangiogenic activity via VEGFR‐2 inhibition, and down‐regulation of P	4
TWIRLS, a knowledge‐mining technology, suggests a possible mechanism for the pathological changes in the human host after coronavirus infection via ACE2	4
Retraction	4
Innovative antimicrobial substances based on uracil S‐derivatives	4
CircATL2 enhances paclitaxel resistance of ovarian cancer via impacting miR‐506‐3p/NFIB axis	4
Novel strategies to oral delivery of insulin: Current progress of nanocarriers for diabetes management	4
Lifitegrast, a Lymphocyte Function‐Associated Antigen‐1 Antagonist Demonstrates Beneficial Effect in Psoriasis	4
Phosphate moiety in FDA‐approved pharmaceutical salts and prodrugs	4
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m6A‐activated BACH1 exacerbates ferroptosis by epigenetic suppression HSPB1 in severe acute pancreatitis	4
Effective and transient mapping of protein–protein interactions: Application of novel releasable photoaffinity linkers	4
Synthesis, antitubercular evaluation, and molecular docking studies of hybrid pyridinium salts derived from isoniazid	4
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Apatinib weakens resistance of gastric cancer cells to paclitaxel by suppressing JAK/STAT3 signaling pathway	4
Synthesis, biological evaluation, and in silico study of novel library sulfonates containing quinazolin‐4(3H)‐one derivatives as potential aldose reductase inhibitors	4
Mesenchymal stem cell‐derived rapid drug screening system for Alzheimer's disease for the identification of novel drugs	4
Neobavaisoflavone protects osteoblasts from dexamethasone‐induced oxidative stress by upregulating the CRNDE‐mediated Nrf2/HO‐1 signaling pathway	4
Dendrobine modulates autophagy to alleviate ox‐LDL‐induced oxidative stress and senescence in HUVECs	4
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Treatment strategies and pharmacist‐led medication management for Helicobacter pylori infection	4
Andrographolide Mitigates Cisplatin Resistance by Inhibiting SPP1 Regulated NF‐kB/iNOS/COX‐2 and PI3K/AKT Pathway in Cisplatin Resistant Cervical Carcinoma Cells	4
Dendrobine regulates STAT3 to attenuate mitochondrial dysfunction and senescence in vascular endothelial cells triggered by oxidized low‐density lipoprotein	4
The potential of developing a protective peptide‐based vaccines against SARS‐CoV‐2	4
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Downregulation of short‐stature homeobox protein 2 suppresses gastric cancer cell growth and stemness in vitro and in vivo via inactivating wnt/β‐catenin signaling	4
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Effect of tramadol on apoptosis and synaptogenesis in hippocampal neurons: The possible role of µ‐opioid receptor	3
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Design, synthesis, and antitumor evaluation of trimethoxyflavonoid with arylurea structure against hepatocellular carcinoma	3
Anti‐allodynic and anti‐hyperalgesic activity of (±)‐licarin A in neuropathic rats via NO‐cyclic‐GMP‐ATP‐sensitive K+ channel pathway	3
Combined chemotherapy of zoledronic acid and pamidronate in the treatment of bone metastases from nonsmall cell lung cancer and the effects on pain stress and bone metabolic indices	3
mAKAPβ signalosome: A potential target for cardiac hypertrophy	3
Paeonol inhibits chronic constriction injury‐induced astrocytic activation and neuroinflammation in rats via the HDAC/miR‐15a pathway	3
68Ga‐labeled, imatinib encapsulated, theranostic liposomes: Formulation, characterization, and in vitro evaluation of anticancer activity	3
Synthesis of new N‐(5,6‐methylenedioxybenzothiazole‐2‐yl)‐2‐[(substituted)thio/piperazine]acetamide/propanamide derivatives and evaluation of their AChE, BChE, and BACE‐1 inhibitory activities	3
Advances in natural small molecules on pretranslational regulation of gluconeogenesis	3
Validating linalool as a potential drug for breast cancer treatment based on machine learning and molecular docking	3
Nanovaccines: Immunogenic tumor antigens, targeted delivery, and combination therapy to enhance cancer immunotherapy	3
Comparisons of successful and failed Phase III trials of drugs and biologicals tested for mitigation of oral mucositis in patients being treated with radiotherapy with or without concomitant chemother	3
All‐trans retinoic acid inhibits oxidative stress via ACE2/Ang (1–7)/MasR pathway in renal tubular epithelial cells stimulated with high glucose	3
Sodium Danshensu inhibits the progression of lung cancer by regulating PI3K/Akt signaling pathway	3
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Design, Synthesis, Biological Evaluation and Molecular Docking Study of New 1,3,4‐Thiadiazole‐Based Compounds as EGFR Inhibitors	3
Toad venom bufadienolides and bufotoxins: An updated review	3
Cover Image, Volume 84, Issue 6	3
Click chemistry‐based synthesis of new benzenesulfonamide derivatives bearing triazole ring as selective carbonic anhydrase II inhibitors	3
Computational and experimental analyses of alanine racemase suggest new avenues for developing allosteric small‐molecule antibiotics	3
Investigation of the activity of a novel tropolone in osteosarcoma	3
Xanthones with multiple roles against diabetes: their synthesis, structure‐activity relationship, and mechanism studies	3
Ulinastatin ameliorates the malignant progression of prostate cancer cells by blocking the RhoA/ROCK/NLRP3 pathway	3
Starch‐based “smart” nanomicelles: Potential delivery systems for doxorubicin	3
Ombuin ameliorates diabetic nephropathy in rats by anti‐inflammation and antifibrosis involving Notch 1 and PPAR γ signaling pathways	3
An Inducible Neural Stem Progenitor Cell Model for Testing Therapeutic Interventions Against Neurodegeneration FENIB	3
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Molecular docking, DFT and antiproliferative properties of 4‐(3,4‐dimethoxyphenyl)−3‐(4‐methoxyphenyl)−1‐phenyl‐1H‐pyrazolo[3,4‐b]pyridine as potent anticancer agent with CDK2 and PIM1 inhibition pote	3
Quercetin regulates vascular endothelium function in chronic renal failure via modulation of Eph/Cav‐1 signaling	3
Shikonin attenuates kidney tubular epithelial cells apoptosis, oxidative stress, and inflammatory response through nicotinamide adenine dinucleotide phosphate oxidase 4/PTEN pathway in acute kidney in	3
Microwave‐assisted synthesis of novel steroidal heterocyclic analogs as potent inhibitors of RANKL‐induced osteoclastogenesis	3
Kaempferol suppresses glioma progression and synergistically enhances the antitumor activity of gefitinib by inhibiting the EGFR/SRC/STAT3 signaling pathway	3
Novel 1,3,4‐oxadiazole derivatives of naproxen targeting EGFR: Synthesis, molecular docking studies, and cytotoxic evaluation	3
In Vitro and In Silico Assessment of Antileishmanial Potential of Novel Tri‐ and Penta‐Valent Antimony Complexes With Phenolic Ligands	3
Hydrolysable tannins as a potential therapeutic drug for the human fibrosis‐associated disease	3
Knockdown of ENO1 promotes autophagy dependent‐ferroptosis and suppresses glycolysis in breast cancer cells via the regulation of CST1	3
Kukoamine A inhibits C‐C motif chemokine receptor 5 to attenuate lipopolysaccharide‐induced lung injury	3
Unraveling the Curcumin's Molecular Targets and Its Potential in Suppressing Skin Inflammation Using Network Pharmacology and In Vitro Studies	3
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Exploring the potential of radiolabeled duramycin as an infection imaging probe	2
Silver(I)‐N‐heterocyclic carbene complexes challenge cancer; evaluation of their anticancer properties and in silico studies	2
CircTHBS1 facilitates the progression of interstitial cystitis depending on the regulation of miR‐139‐5p/MFN2 axis	2
Development and evaluation of multi‐functionalized sialic acid conjugated asiatic acid nanoconstruct to mitigate cognitive deficits in Alzheimer's disease	2
RNA editing enzyme adenosine deaminases acting on RNA 1 deficiency increases the sensitivity of non‐small cell lung cancer cells to anlotinib by regulating CX3CR1‐fractalkine exp	2
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PMEPA1 interference activates PTEN/PI3K/AKT, thereby inhibiting the proliferation, invasion and migration of pancreatic cancer cells and enhancing the sensi	2