OOIR: Observatory of International Research

Papers

(The TQCC of Cellular and Molecular Neurobiology is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
In the Rat Midbrain, SG2NA and DJ-1 have Common Interactome, Including Mitochondrial Electron Transporters that are Comodulated Under Oxidative Stress	143
The Role of Non-coding RNAs in Methamphetamine-Induced Neurotoxicity	98
Amygdala Metabotropic Glutamate Receptor 1 Influences Synaptic Transmission to Participate in Fentanyl-Induced Hyperalgesia in Rats	76
Dopamine Activates the D1R-Zn2+ Signaling Pathway to Trigger Inflammatory Response in Primary-Cultured Rat Embryonic Cortical Neurons	68
Altered Distribution of SNARE Proteins in Primary Neurons Exposed to Different Alpha-Synuclein Proteoforms	60
Cognitive Deficits Found in a Pro-inflammatory State are Independent of ERK1/2 Signaling in the Murine Brain Hippocampus Treated with Shiga Toxin 2 from Enterohemorrhagic Escherichia coli	56
Analysis and Regulatory Mechanisms of Platelet-Related Genes in Patients with Ischemic Stroke	51
A Tale of Two: When Neural Stem Cells Encounter Hypoxia	51
A Study on Autophagy Related Biomarkers in Alzheimer’s Disease Based on Bioinformatics	48
Mutation in the TRKB Cholesterol Recognition Site that blocks Antidepressant Binding does not Influence the Basal or BDNF-Stimulated Activation of TRKB	46
Molecular and Regenerative Characterization of Repair and Non-repair Schwann Cells	41
Correction to: The Neuroprotective Effects and Probable Mechanisms of Everolimus in a Rat Model of Intracerebral Hemorrhage	41
The Role of Cannabinoids in CNS Development: Focus on Proliferation and Cell Death	40
Bone Marrow-Derived Mononuclear Cells in the Treatment of Neurological Diseases: Knowns and Unknowns	38
Cellular and Molecular Regulation of Exercise—A Neuronal Perspective	37
The Progress in Molecular Transport and Therapeutic Development in Human Blood–Brain Barrier Models in Neurological Disorders	36
Introduction to the Special Issue “The Brain-Gut Axis”	35
Discovery and Characterization of Ephrin B2 and EphB4 Dysregulation and Novel Mutations in Cerebral Cavernous Malformations: In Vitro and Patient-Derived Evidence of Ephrin-Mediated Endothelial Cell P	34
Expression Profile, Molecular Association, and Clinical Significance of POLD4 in Glioblastoma	34
Correction to: A Risk Signature Consisting of Eight m6A Methylation Regulators Predicts the Prognosis of Glioma	34
Protein Biomarkers in Blood Reflect the Interrelationships Between Stroke Outcome, Inflammation, Coagulation, Adhesion, Senescence and Cancer	33
Laser-Induced Axotomy of Human iPSC-Derived and Murine Primary Neurons Decreases Somatic Tau and AT8 Tau Phosphorylation: A Single-Cell Approach to Study Effects of Acute Axonal Damage	32
Potential Role of Epigenetics and Redox Signaling in the Gut–Brain Communication and the Case of Autism Spectrum Disorder	31
Genetic Discrimination of Grade 3 and Grade 4 Gliomas by Artificial Neural Network	31
Clinical Insights on Caloric Restriction Mimetics for Mitigating Brain Aging and Related Neurodegeneration	29

Viruses and Mitochondrial Dysfunction in Neurodegeneration and Cognition: An Evolutionary Perspective	29
Drivers of Chronic Pathology Following Ischemic Stroke: A Descriptive Review	29
Can Environmental Enrichment Modulate Epigenetic Processes in the Central Nervous System Under Adverse Environmental Conditions? A Systematic Review	28
Effect of Heat Stress on Hippocampal Neurogenesis: Insights into the Cellular and Molecular Basis of Neuroinflammation-Induced Deficits	28
Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders	27
Inhibition of the Proteasome Regulator PA28 Aggravates Oxidized Protein Overload in the Diabetic Rat Brain	27
Fetal Brain Damage in Human Fetuses with Congenital Cytomegalovirus Infection: Histological Features and Viral Tropism	27
Correction: Proteomic and Cytokine Profiling in Plasma from Patients with Normal-Tension Glaucoma and Ocular Hypertension	27
The Role of Retinal Dysfunction in Myopia Development	26
Inhibition of UHRF1 Improves Motor Function in Mice with Spinal Cord Injury	26
Klotho Upregulation via PPARγ Contributes to the Induction of Brain Ischemic Tolerance by Cerebral Ischemic Preconditioning in Rats	26
Disease-Associated Neurotoxic Astrocyte Markers in Alzheimer Disease Based on Integrative Single-Nucleus RNA Sequencing	26
Tau Aggregation Inhibiting Peptides as Potential Therapeutics for Alzheimer Disease	26
Systematic Analysis of RNA Expression Profiles in Different Ischemic Cortices in MCAO Mice	26
Role of Adenosine Kinase in Sphingosine-1-Phosphate Receptor 1-Induced Mechano-Hypersensitivities	25
Iron Deposition in Parkinson’s Disease: A Mini-Review	24
Research Progress on the Immune-Inflammatory Mechanisms of Posttraumatic Epilepsy	23
Screening Plasma Proteins for the Putative Drug Targets for Carpal Tunnel Syndrome	23
Lanthanum Chloride Induces Axon Abnormality Through LKB1-MARK2 and LKB1-STK25-GM130 Signaling Pathways	23
Pesticide Exposure and Its Association with Parkinson’s Disease: A Case–Control Analysis	22
Relevance of Thymic Stromal Lymphopoietin on the Pathogenesis of Glioblastoma: Role of the Neutrophil	22
Finding an Optimal Level of GDNF Overexpression: Insights from Dopamine Cycling	20
Bi-Directional Relationship Between Autophagy and Inflammasomes in Neurodegenerative Disorders	20
The Role of ERK1/2 Pathway in the Pathophysiology of Alzheimer’s Disease: An Overview and Update on New Developments	20
The Provenance, Providence, and Position of Endothelial Cells in Injured Spinal Cord Vascular Pathology	19
AQP4 is an Emerging Regulator of Pathological Pain: A Narrative Review	19
Proteomic and Cytokine Profiling in Plasma from Patients with Normal-Tension Glaucoma and Ocular Hypertension	19
Are mGluR2/3 Inhibitors Potential Compounds for Novel Antidepressants?	19
Correction: Upregulation of Glutamatergic Receptors in Hippocampus and Locomotor Hyperactivity in Aged Spontaneous Hypertensive Rat	19
Primary Hypothyroidism and Alzheimer’s Disease: A Tale of Two	18
Treadmill Running Regulates Adult Neurogenesis, Spatial and Non-spatial Learning, Parvalbumin Neuron Activity by ErbB4 Signaling	18
A Carboxy-terminal Smarcb1 Point Mutation Induces Hydrocephalus Formation and Affects AP-1 and Neuronal Signalling Pathways in Mice	18
Dietary Fiber Modulates the Release of Gut Bacterial Products Preventing Cognitive Decline in an Alzheimer’s Mouse Model	18
ACh Transfers: Homeostatic Plasticity of Cholinergic Synapses	16
Correction: Effect of Induction Time on the Proliferation and Differentiation of Induced Schwann‑Like Cells from Adipose‑Derived Stem Cells	16
Navigating the Landscape of MANF Research: A Scientometric Journey with CiteSpace Analysis	16
Prenatal Exposure to General Anesthesia Drug Esketamine Impaired Neurobehavior in Offspring	16
The Role of Beta2-Microglobulin in Central Nervous System Disease	16
The Mechanisms of Ferroptosis Under Hypoxia	16
REST in the Road Map of Brain Development	16
FAM3A Ameliorates Brain Impairment Induced by Hypoxia–Ischemia in Neonatal Rat	16
The Role of Inflammatory Cascade and Reactive Astrogliosis in Glial Scar Formation Post-spinal Cord Injury	15
A Bibliometric Analysis of the Spatial Transcriptomics Literature from 2006 to 2023	15
Retraction Note: The Interplay of Tau Protein and β-Amyloid: While Tauopathy Spreads More Profoundly Than Amyloidopathy, Both Processes Are Almost Equally Pathogenic	15
Mesenchymal Stromal Cells-Derived Exosome and the Roles in the Treatment of Traumatic Brain Injury	15
Human Oral Mucosa Stem Cells Increase Survival of Neurons Affected by In Vitro Anoxia and Improve Recovery of Mice Affected by Stroke Through Time-limited Secretion of miR-514A-3p	15
Experiences Shape Hippocampal Neuron Morphology and the Local Levels of CRHR1 and OTR	15
Pathophysiology, Diagnosis, Treatment, and Genetics of Carpal Tunnel Syndrome: A Review	15
Potential Prion Involvement in Long COVID-19 Neuropathology, Including Behavior	15
S-Ketamine Exerts Antidepressant Effects by Regulating Rac1 GTPase Mediated Synaptic Plasticity in the Hippocampus of Stressed Rats	15

Synergistic Epistasis and Systems Biology Approaches to Uncover a Pharmacogenomic Map Linked to Pain, Anti-Inflammatory and Immunomodulating Agents (PAIma) in a Healthy Cohort	14
Neuromodulation Through Magnetic Fields Irradiation with AT-04 Improves Hyperalgesia in a Rat Model of Neuropathic Pain via Descending Pain Modulatory Systems and Opioid Analgesia	14
The Critical Role of RNA m6A Methylation in Gliomas: Targeting the Hallmarks of Cancer	14
Hypoglycemia and Alzheimer Disease Risk: The Possible Role of Dasiglucagon	14
Neurological Consequences, Mental Health, Physical Care, and Appropriate Nutrition in Long-COVID-19	14
Neuroepigenetic Changes in DNA Methylation Affecting Diabetes-Induced Cognitive Impairment	14
Identifying Candidate Genes Associated with Sporadic Amyotrophic Lateral Sclerosis via Integrative Analysis of Transcriptome-Wide Association Study and Messenger RNA Expression Profile	14
Activation of TRPV1 Channels Inhibits the Release of Acetylcholine and Improves Muscle Contractility in Mice	13
Mechanism of Cone Degeneration in Retinitis Pigmentosa	13
TIMP-3 Alleviates White Matter Injury After Subarachnoid Hemorrhage in Mice by Promoting Oligodendrocyte Precursor Cell Maturation	13
Advanced Overview of Biomarkers and Techniques for Early Diagnosis of Alzheimer’s Disease	13
Enlarged Perivascular Space and Index for Diffusivity Along the Perivascular Space as Emerging Neuroimaging Biomarkers of Neurological Diseases	13
Trehalose–Carnosine Prevents the Effects of Spinal Cord Injury Through Regulating Acute Inflammation and Zinc(II) Ion Homeostasis	13
Role of Ferroptosis in Stroke	13
Elabela, a Novel Peptide, Exerts Neuroprotective Effects Against Ischemic Stroke Through the APJ/miR-124-3p/CTDSP1/AKT Pathway	13
Uncovering the Significance of STEP61 in Alzheimer’s Disease: Structure, Substrates, and Interactome	12
Distinct DNA Methylation Patterns of Subependymal Giant Cell Astrocytomas in Tuberous Sclerosis Complex	12
Roles of ApoE4 on the Pathogenesis in Alzheimer’s Disease and the Potential Therapeutic Approaches	12
Urine Proteomic Signatures of Mild Hypothermia Treatment in Cerebral Ischemia–Reperfusion Injury in Rats	12
Correction: Upregulation of miR-107 Inhibits Glioma Angiogenesis and VEGF Expression	12
Defensive and Emotional Behavior Modulation by Serotonin in the Periaqueductal Gray	12
Do Sleep Disturbances have a Dual Effect on Alzheimer’s Disease?	12
Phosphodiesterase-4 Inhibition in Parkinson’s Disease: Molecular Insights and Therapeutic Potential	12
Role of NAD+ and FAD in Ischemic Stroke Pathophysiology: An Epigenetic Nexus and Expanding Therapeutic Repertoire	12
Liquid Biopsy in Low-Grade Glioma: A Systematic Review and a Proposal for a Clinical Utility Score	12
CircSKA3 is Associated With the Risk of Extracranial Artery Stenosis and Plaque Instability Among Ischemic Stroke Patients	12
A Pilot Study of Ex Vivo Human Prefrontal RNA Transcriptomics in Parkinson’s Disease	12