Cellular and Molecular Neurobiology

Article	Citations
SARS-CoV-2 Infectivity and Neurological Targets in the Brain	121
The Roles of Serotonin in Neuropsychiatric Disorders	78
Inhibition of Ferroptosis Alleviates Early Brain Injury After Subarachnoid Hemorrhage In Vitro and In Vivo via Reduction of Lipid Peroxidation	76
Expression of ACE2 in Human Neurons Supports the Neuro-Invasive Potential of COVID-19 Virus	74
The Gut-Brain Axis: Two Ways Signaling in Parkinson’s Disease	44
Oxycodone in the Opioid Epidemic: High ‘Liking’, ‘Wanting’, and Abuse Liability	41
Building a Bridge Between NMDAR-Mediated Excitotoxicity and Mitochondrial Dysfunction in Chronic and Acute Diseases	39
Blood–Brain Barrier Dysfunction in the Pathogenesis of Major Depressive Disorder	38
An Immune-Related lncRNA Signature to Predict Survival In Glioma Patients	38
SIRT1 Activation by Polydatin Alleviates Oxidative Damage and Elevates Mitochondrial Biogenesis in Experimental Diabetic Neuropathy	37
Autism Spectrum Disorder: Signaling Pathways and Prospective Therapeutic Targets	36
Kratom Alkaloids, Natural and Semi-Synthetic, Show Less Physical Dependence and Ameliorate Opioid Withdrawal	36
Role of Ferroptosis in Stroke	35
MicroRNA: An Emerging Predictive, Diagnostic, Prognostic and Therapeutic Strategy in Ischaemic Stroke	34
Hypoxic Preconditioning Enhances the Efficacy of Mesenchymal Stem Cells-Derived Conditioned Medium in Switching Microglia toward Anti-inflammatory Polarization in Ischemia/Reperfusion	34
The Role of VPS35 in the Pathobiology of Parkinson’s Disease	34
Morphine and Fentanyl Repeated Administration Induces Different Levels of NLRP3-Dependent Pyroptosis in the Dorsal Raphe Nucleus of Male Rats via Cell-Specific Activation of TLR4 and Opioid Receptors	33
LncRNA HOTAIR Promotes Neuronal Damage Through Facilitating NLRP3 Mediated-Pyroptosis Activation in Parkinson’s Disease via Regulation of miR-326/ELAVL1 Axis	33
The Molecular Mechanisms of Action of Photobiomodulation Against Neurodegenerative Diseases: A Systematic Review	33
Involvement of α7nAChR in the Protective Effects of Genistein Against β-Amyloid-Induced Oxidative Stress in Neurons via a PI3K/Akt/Nrf2 Pathway-Related Mechanism	32
Role of Microgliosis and NLRP3 Inflammasome in Parkinson’s Disease Pathogenesis and Therapy	31
Evodiamine Inhibits Lipopolysaccharide (LPS)-Induced Inflammation in BV-2 Cells via Regulating AKT/Nrf2-HO-1/NF-κB Signaling Axis	30
Epigenetic Changes and Its Intervention in Age-Related Neurodegenerative Diseases	30
Sirt3 Protects Against Ischemic Stroke Injury by Regulating HIF-1α/VEGF Signaling and Blood–Brain Barrier Integrity	30
LncRNA MEG8 Attenuates Cerebral Ischemia After Ischemic Stroke Through Targeting miR-130a-5p/VEGFA Signaling	30

Mesenchymal Stem Cells Ameliorate Cuprizone-Induced Demyelination by Targeting Oxidative Stress and Mitochondrial Dysfunction	29
Lithium as a Neuroprotective Agent for Bipolar Disorder: An Overview	29
The Microbiota–Gut–Brain Axis and Epilepsy	29
Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders	28
Extracellular Matrix in Neural Plasticity and Regeneration	27
LncRNA H19 Promotes Cell Proliferation, Migration, and Angiogenesis of Glioma by Regulating Wnt5a/β-Catenin Pathway via Targeting miR-342	26
Mitophagy, a Form of Selective Autophagy, Plays an Essential Role in Mitochondrial Dynamics of Parkinson’s Disease	26
Adaptive Changes Allow Targeting of Ferroptosis for Glioma Treatment	24
Liposomal Carrier Conjugated to APP-Derived Peptide for Brain Cancer Treatment	24
Evidence that Oxidative Disbalance and Mitochondrial Dysfunction are Involved in the Pathophysiology of Fatty Acid Oxidation Disorders	23
Knocking Out Sigma-1 Receptors Reveals Diverse Health Problems	23
Role of MicroRNAs, Aptamers in Neuroinflammation and Neurodegenerative Disorders	22
Dysbiosis and Alzheimer’s Disease: Cause or Treatment Opportunity?	22
COVID-19, Angiotensin Receptor Blockers, and the Brain	22
In Vivo Targeting of the Neurovascular Unit: Challenges and Advancements	22
Parkin, an E3 Ubiquitin Ligase, Plays an Essential Role in Mitochondrial Quality Control in Parkinson’s Disease	22
The Role of ERK1/2 Pathway in the Pathophysiology of Alzheimer’s Disease: An Overview and Update on New Developments	21
Immortalised Hippocampal Astrocytes from 3xTG-AD Mice Fail to Support BBB Integrity In Vitro: Role of Extracellular Vesicles in Glial-Endothelial Communication	21
Tetramethylpyrazine Protects Blood-Spinal Cord Barrier Integrity by Modulating Microglia Polarization Through Activation of STAT3/SOCS3 and Inhibition of NF-кB Signaling Pathways in Experimental Autoi	21
Knockdown of TRIM22 Relieves Oxygen–Glucose Deprivation/Reoxygenation-Induced Apoptosis and Inflammation Through Inhibition of NF-κB/NLRP3 Axis	21
LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β-Catenin Pathway Via Binding to PTBP1 in Glioma	21
Roles of the miR-155 in Neuroinflammation and Neurological Disorders: A Potent Biological and Therapeutic Target	21
Differential Modulators of NG2-Glia Differentiation into Neurons and Glia and Their Crosstalk	21
Harsh Parenting Predicts Novel HPA Receptor Gene Methylation and NR3C1 Methylation Predicts Cortisol Daily Slope in Middle Childhood	21
FTY720 Modulates Microglia Toward Anti-inflammatory Phenotype by Suppressing Autophagy via STAT1 Pathway	20
GJA1-20K Enhances Mitochondria Transfer from Astrocytes to Neurons via Cx43-TnTs After Traumatic Brain Injury	20
Hyperhomocysteinemia-Induced Oxidative Stress Exacerbates Cortical Traumatic Brain Injury Outcomes in Rats	20
Non-visual Opsins and Novel Photo-Detectors in the Vertebrate Inner Retina Mediate Light Responses Within the Blue Spectrum Region	20
Coronavirus Disease 2019 (COVID-19) and Its Neuroinvasive Capacity: Is It Time for Melatonin?	19
GANT-61 Induces Autophagy and Apoptosis in Glioblastoma Cells despite their heterogeneity	19
The Effects of Proton Pump Inhibitors (Pantoprazole) on Pentylenetetrazole-Induced Epileptic Seizures in Rats and Neurotoxicity in the SH-SY5Y Human Neuroblastoma Cell Line	19
Hemorrhagic Transformation After Tissue Plasminogen Activator Treatment in Acute Ischemic Stroke	19
Epidermal Growth Factor in the CNS: A Beguiling Journey from Integrated Cell Biology to Multiple Sclerosis. An Extensive Translational Overview	19
microRNA-381-3p Confers Protection Against Ischemic Stroke Through Promoting Angiogenesis and Inhibiting Inflammation by Suppressing Cebpb and Map3k8	19
Role of DAMPs and of Leukocytes Infiltration in Ischemic Stroke: Insights from Animal Models and Translation to the Human Disease	19
Understanding Abnormal SMO-SHH Signaling in Autism Spectrum Disorder: Potential Drug Target and Therapeutic Goals	19
Metabolic Regulation of Glia and Their Neuroinflammatory Role in Alzheimer's Disease	19
Dietary Fiber Modulates the Release of Gut Bacterial Products Preventing Cognitive Decline in an Alzheimer’s Mouse Model	18
Hyperammonemia in Inherited Metabolic Diseases	18
Functional Two-Way Crosstalk Between Brain and Lung: The Brain–Lung Axis	17
MircoRNA-29a in Astrocyte-derived Extracellular Vesicles Suppresses Brain Ischemia Reperfusion Injury via TP53INP1 and the NF-κB/NLRP3 Axis	17
Miro1 Regulates Neuronal Mitochondrial Transport and Distribution to Alleviate Neuronal Damage in Secondary Brain Injury After Intracerebral Hemorrhage in Rats	17
Melatonin Provides Neuroprotection Following Traumatic Brain Injury-Promoted Mitochondrial Perturbation in Wistar Rat	17
TNF-α Triggers RIP1/FADD/Caspase-8-Mediated Apoptosis of Astrocytes and RIP3/MLKL-Mediated Necroptosis of Neurons Induced by Angiostrongylus cantonensis Infection	16
Tau Aggregation Inhibiting Peptides as Potential Therapeutics for Alzheimer Disease	16
Autophagic Pathways to Clear the Tau Aggregates in Alzheimer’s Disease	16
Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1	16
Cerebrospinal Fluid Profile of Lipid Mediators in Alzheimer’s Disease	16
Improved Spatial Memory And Neuroinflammatory Profile Changes in Aged Rats Submitted to Photobiomodulation Therapy	16
Elastin-Derived Peptides in the Central Nervous System: Friend or Foe	16

The Role of Ferroptosis in Blood–Brain Barrier Injury	16
Heterogeneity and Molecular Markers for CNS Glial Cells Revealed by Single-Cell Transcriptomics	15
Overview of the Neuroprotective Effects of the MAO-Inhibiting Antidepressant Phenelzine	15
The Role of AMPARs Composition and Trafficking in Synaptic Plasticity and Diseases	15
The Angiotensin Type 1 Receptor Antagonist Losartan Prevents Ovariectomy-Induced Cognitive Dysfunction and Anxiety-Like Behavior in Long Evans Rats	15
The Mechanistic Role of Bridging Integrator 1 (BIN1) in Alzheimer’s Disease	15
Modulation of α7nAchR by Melatonin Alleviates Ischemia and Reperfusion-Compromised Integrity of Blood–Brain Barrier Through Inhibiting HMGB1-Mediated Microglia Activation and CRTC1-Mediated Neuronal L	15
A 1p/19q Codeletion-Associated Immune Signature for Predicting Lower Grade Glioma Prognosis	14
New Insights into Stroke Prevention and Treatment: Gut Microbiome	14
Probiotics and the Treatment of Parkinson's Disease: An Update	14
LncRNA CCAT1 Protects Astrocytes Against OGD/R-Induced Damage by Targeting the miR-218/NFAT5-Signaling Axis	14
Mitochondrial DNA Heteroplasmy as an Informational Reservoir Dynamically Linked to Metabolic and Immunological Processes Associated with COVID-19 Neurological Disorders	13
Neuroprotective Effect of 2-Aminoethoxydiphenyl Borate (2-APB) in Amyloid β-Induced Memory Dysfunction: A Mechanistic Study	13
Main Role of Antibodies in Demyelination and Axonal Damage in Multiple Sclerosis	13
Opioid Receptor Regulation of Neuronal Voltage-Gated Calcium Channels	13
Preclinical Stroke Research and Translational Failure: A Bird’s Eye View on Preventable Variables	13
Mechanisms of Regulation and Diverse Activities of Tau-Tubulin Kinase (TTBK) Isoforms	13
Microglia as the Critical Regulators of Neuroprotection and Functional Recovery in Cerebral Ischemia	13
A Novel Role of Nogo Proteins: Regulating Macrophages in Inflammatory Disease	13
Regulation of PGE2 Pathway During Cerebral Ischemia Reperfusion Injury in Rat	13
Chronic Pain Causes Peripheral and Central Responses in MIA-Induced TMJOA Rats	13
Long Noncoding RNA KCNQ1OT1 Confers Gliomas Resistance to Temozolomide and Enhances Cell Growth by Retrieving PIM1 From miR-761	13
Multiomic Analyses of Dopaminergic Neurons Isolated from Human Substantia Nigra in Parkinson’s Disease: A Descriptive and Exploratory Study	13
The Notch Signaling Pathway Regulates Differentiation of NG2 Cells into Oligodendrocytes in Demyelinating Diseases	13
RETRACTED ARTICLE: The Interplay of Tau Protein and β-Amyloid: While Tauopathy Spreads More Profoundly Than Amyloidopathy, Both Processes Are Almost Equally Pathogenic	12
Supraspinal Mechanisms of Intestinal Hypersensitivity	12
Regulation of Opioid Receptors by Their Endogenous Opioid Peptides	12
Proinflammatory Extracellular Vesicle-Mediated Signaling Contributes to the Induction of Neuroinflammation in Animal Models of Endotoxemia and Peripheral Surgical Stress	12
Abscisic Acid-Induced Autophagy Selectively via MAPK/JNK Signalling Pathway in Glioblastoma	12
Upregulation of KIF11 in TP53 Mutant Glioma Promotes Tumor Stemness and Drug Resistance	11
Procalcitonin related to stroke-associated pneumonia and clinical outcomes of acute ischemic stroke after IV rt-PA treatment	11
Time-Dependent Memory and Gait Improvement by Intranasally-Administered Extracellular Vesicles in Parkinson’s Disease Model Rats	11
Ryanodine Receptors: A Potential Treatment Target in Various Neurodegenerative Disease	11
Valproic Acid Sensitizes Glioma Cells to Luteolin Through Induction of Apoptosis and Autophagy via Akt Signaling	11
Fetal Brain Damage in Human Fetuses with Congenital Cytomegalovirus Infection: Histological Features and Viral Tropism	11
Lipid Rafts from Olfactory Ensheathing Cells: Molecular Composition and Possible Roles	11
Estrogen Protects Optic Nerve Head Astrocytes Against Oxidative Stress by Preventing Caspase-3 Activation, Tau Dephosphorylation at Ser422 and the Formation of Tau Protein Aggregates	11
The Active Role of Pericytes During Neuroinflammation in the Adult Brain	11
Sevoflurane Post-Conditioning Ameliorates Neuronal Deficits and Axon Demyelination After Neonatal Hypoxic Ischemic Brain Injury: Role of Microglia/Macrophage	11
Role of Pyroptosis, a Pro-inflammatory Programmed Cell Death, in Epilepsy	11
Role of Altered Expression, Activity and Sub-cellular Distribution of Various Histone Deacetylases (HDACs) in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis	11
Lactate and Lactylation in the Brain: Current Progress and Perspectives	11
Purinergic Receptors Crosstalk with CCR5 to Amplify Ca2+ Signaling	10
miR-132 Regulates PTSD-like Behaviors in Rats Following Single-Prolonged Stress Through Fragile X-Related Protein 1	10
LncRNA LINC01410 Induced by MYC Accelerates Glioma Progression via Sponging miR-506-3p and Modulating NOTCH2 Expression to Motivate Notch Signaling Pathway	10
Neurological Consequences, Mental Health, Physical Care, and Appropriate Nutrition in Long-COVID-19	10
Real-Time Noninvasive Bioluminescence, Ultrasound and Photoacoustic Imaging in NFκB-RE-Luc Transgenic Mice Reveal Glia Maturation Factor-Mediated Immediate and Sustained Spatio-Temporal Activation of	10
EphA4 Obstructs Spinal Cord Neuron Regeneration by Promoting Excessive Activation of Astrocytes	10
High Glucose and Hypoxia-Mediated Damage to Human Brain Microvessel Endothelial Cells Induces an Altered, Pro-Inflammatory Phenotype in BV-2 Microglia In Vitro	10
Sarm1 is Essential for Anesthesia-Induced Neuroinflammation and Cognitive Impairment in Aged Mice	10
Role of Microglia in Regulating Cholesterol and Tau Pathology in Alzheimer’s Disease	10
[Pt(O,O'-acac)(γ-acac)(DMS)]: Alternative Strategies to Overcome Cisplatin-Induced Side Effects and Resistance in T98G Glioma Cells	10
TRAF6 Contributes to CFA-Induced Spinal Microglial Activation and Chronic Inflammatory Pain in Mice	10
Mitochondria-ER Tethering in Neurodegenerative Diseases	10
Neuroprotective Effects of Early Brain Injury after Subarachnoid Hemorrhage in Rats by Calcium Channel Mediating Hydrogen Sulfide	10
Mitochondrial Dysfunction and Redox Homeostasis Impairment as Pathomechanisms of Brain Damage in Ethylmalonic Encephalopathy: Insights from Animal and Human Studies	10
Synthesis of the Mechanisms of Opioid Tolerance: Do We Still Say NO?	10
Progesterone and Allopregnanolone Neuroprotective Effects in the Wobbler Mouse Model of Amyotrophic Lateral Sclerosis	10
Brainstem Neuronal Circuitries Controlling Gastric Tonic and Phasic Contractions: A Review	10
Divergent Dimethylarginine Dimethylaminohydrolase Isoenzyme Expression in the Central Nervous System	9
Wnt3a/YTHDF1 Regulated Oxaliplatin-Induced Neuropathic Pain Via TNF-α/IL-18 Expression in the Spinal Cord	9
Arundic Acid (ONO-2506) Attenuates Neuroinflammation and Prevents Motor Impairment in Rats with Intracerebral Hemorrhage	9
TNFα Triggers an Augmented Inflammatory Response in Brain Neurons from Dahl Salt-Sensitive Rats Compared with Normal Sprague Dawley Rats	9
The Bridge Between Ischemic Stroke and Gut Microbes: Short-Chain Fatty Acids	9
Maturing Autophagosomes are Transported Towards the Cell Periphery	9
Oxidative Stress-Involved Mitophagy of Retinal Pigment Epithelium and Retinal Degenerative Diseases	9
A Risk Signature Consisting of Eight m6A Methylation Regulators Predicts the Prognosis of Glioma	9
Exogenous Adenosine Antagonizes Excitatory Amino Acid Toxicity in Primary Astrocytes	9
miR-4286 is Involved in Connections Between IGF-1 and TGF-β Signaling for the Mesenchymal Transition and Invasion by Glioblastomas	9
GSK-3β Disrupts Neuronal Oscillatory Function to Inhibit Learning and Memory in Male Rats	9
Microtubule Dynamics and Neuronal Excitability: Advances on Cytoskeletal Components Implicated in Epileptic Phenomena	9
Apelin Receptor Signaling Protects GT1-7 GnRH Neurons Against Oxidative Stress In Vitro	9
Proteomic Profiling of Cerebrum Mitochondria, Myelin Sheath, and Synaptosome Revealed Mitochondrial Damage and Synaptic Impairments in Association with 3 × Tg‐AD Mice Model	9
STAT3 Contributes to Intracranial Aneurysm Formation and Rupture by Modulating Inflammatory Response	9
Upregulation of miR-499a-5p Decreases Cerebral Ischemia/Reperfusion Injury by Targeting PDCD4	9
MicroRNA-137-3p Protects PC12 Cells Against Oxidative Stress by Downregulation of Calpain-2 and nNOS	9
Oxytocin Prevents the Development of 3-NP-Induced Anxiety and Depression in Male and Female Rats: Possible Interaction of OXTR and mGluR2	9
S-Ketamine Exerts Antidepressant Effects by Regulating Rac1 GTPase Mediated Synaptic Plasticity in the Hippocampus of Stressed Rats	9
Cardiac Neural Crest Cells: Their Rhombomeric Specification, Migration, and Association with Heart and Great Vessel Anomalies	9
miR-124: A Promising Therapeutic Target for Central Nervous System Injuries and Diseases	9

Alcohol alters IL-6 Signal Transduction in the CNS of Transgenic Mice with Increased Astrocyte Expression of IL-6	8
Hypothermia Attenuates Neuronal Damage via Inhibition of Microglial Activation, Including Suppression of Microglial Cytokine Production and Phagocytosis	8
Pathophysiology, Diagnosis, Treatment, and Genetics of Carpal Tunnel Syndrome: A Review	8
Girl Power in Glaucoma: The Role of Estrogen in Primary Open Angle Glaucoma	8
Necroptotic–Apoptotic Regulation in an Endothelin-1 Model of Cerebral Ischemia	8
Synthesis and Characterization of Azido Aryl Analogs of IBNtxA for Radio-Photoaffinity Labeling Opioid Receptors in Cell Lines and in Mouse Brain	8
Mechanism of Cone Degeneration in Retinitis Pigmentosa	8
Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord	8
Advanced Overview of Biomarkers and Techniques for Early Diagnosis of Alzheimer’s Disease	8
Long Non-Coding RNAs in Retinal Ganglion Cell Apoptosis	8
Pathway-Focused Profiling of Oligodendrocytes Over-Expressing miR-125a-3p Reveals Alteration of Wnt and Cell-to-Cell Signaling	8
Effects of Compound 511 on BDNF-TrkB Signaling in the Mice Ventral Tegmental Area in Morphine-Induced Conditioned Place Preference	8
Protein Aggregation in the Pathogenesis of Ischemic Stroke	8
FOXO3 Regulates Sevoflurane-Induced Neural Stem Cell Differentiation in Fetal Rats	8
Histamine H3 Receptor Activation Modulates Glutamate Release in the Corticostriatal Synapse by Acting at CaV2.1 (P/Q-Type) Calcium Channels and GIRK (KIR3) Potassium Channels	8
Ketogenic Diet Modulates Neuroinflammation via Metabolites from Lactobacillus reuteri After Repetitive Mild Traumatic Brain Injury in Adolescent Mice	8
Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia–Reperfusion Injury Rats	8
The Effects of Serum Removal on Gene Expression and Morphological Plasticity Markers in Differentiated SH-SY5Y Cells	8
Nicotinic Acetylcholine Receptors of PC12 Cells	8
Altered MicroRNA Expression in Intracranial Aneurysmal Tissues: Possible Role in TGF-β Signaling Pathway	8
Curcumin Improves Human Umbilical Cord-Derived Mesenchymal Stem Cell Survival via ERK1/2 Signaling and Promotes Motor Outcomes After Spinal Cord Injury	8
Evidence for Menopause as a Sex-Specific Risk Factor for Glaucoma	8
The CXCL12/CXCR4/ACKR3 Response Axis in Chronic Neurodegenerative Disorders of the Central Nervous System: Therapeutic Target and Biomarker	8
Circ-EGFR Functions as an Inhibitory Factor in the Malignant Progression of Glioma by Regulating the miR-183-5p/TUSC2 Axis	8
MMP-9 Inhibitor GM6001 Prevents the Development of ssTBI-Induced Parkinson’s Disease via the Autophagy Pathway	8
Roles of Phosphorylation of N-Methyl-d-Aspartate Receptor in Chronic Pain	8
Changes in the Brain Extracellular Matrix Composition in schizophrenia: A Pathophysiological Dysregulation and a Potential Therapeutic Target	8
Therapeutic Potential of Berberine in the Treatment of Glioma: Insights into Its Regulatory Mechanisms	8