OOIR: Observatory of International Research

Papers

(The median citation count of Cellular and Molecular Neurobiology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
In the Rat Midbrain, SG2NA and DJ-1 have Common Interactome, Including Mitochondrial Electron Transporters that are Comodulated Under Oxidative Stress	215
Cognitive Deficits Found in a Pro-inflammatory State are Independent of ERK1/2 Signaling in the Murine Brain Hippocampus Treated with Shiga Toxin 2 from Enterohemorrhagic Escherichia coli	120
Amygdala Metabotropic Glutamate Receptor 1 Influences Synaptic Transmission to Participate in Fentanyl-Induced Hyperalgesia in Rats	95
Altered Distribution of SNARE Proteins in Primary Neurons Exposed to Different Alpha-Synuclein Proteoforms	83
A Study on Autophagy Related Biomarkers in Alzheimer’s Disease Based on Bioinformatics	82
Dopamine Activates the D1R-Zn2+ Signaling Pathway to Trigger Inflammatory Response in Primary-Cultured Rat Embryonic Cortical Neurons	76
Analysis and Regulatory Mechanisms of Platelet-Related Genes in Patients with Ischemic Stroke	75
A Tale of Two: When Neural Stem Cells Encounter Hypoxia	74
The Role of Non-coding RNAs in Methamphetamine-Induced Neurotoxicity	67
Correction to: The Neuroprotective Effects and Probable Mechanisms of Everolimus in a Rat Model of Intracerebral Hemorrhage	62
Cellular and Molecular Regulation of Exercise—A Neuronal Perspective	61
Molecular and Regenerative Characterization of Repair and Non-repair Schwann Cells	61
The Role of Cannabinoids in CNS Development: Focus on Proliferation and Cell Death	49
Mutation in the TRKB Cholesterol Recognition Site that blocks Antidepressant Binding does not Influence the Basal or BDNF-Stimulated Activation of TRKB	49
Bone Marrow-Derived Mononuclear Cells in the Treatment of Neurological Diseases: Knowns and Unknowns	49
Expression Profile, Molecular Association, and Clinical Significance of POLD4 in Glioblastoma	47
Discovery and Characterization of Ephrin B2 and EphB4 Dysregulation and Novel Mutations in Cerebral Cavernous Malformations: In Vitro and Patient-Derived Evidence of Ephrin-Mediated Endothelial Cell P	47
The Progress in Molecular Transport and Therapeutic Development in Human Blood–Brain Barrier Models in Neurological Disorders	43
Drivers of Chronic Pathology Following Ischemic Stroke: A Descriptive Review	42
Clinical Insights on Caloric Restriction Mimetics for Mitigating Brain Aging and Related Neurodegeneration	39
Protein Biomarkers in Blood Reflect the Interrelationships Between Stroke Outcome, Inflammation, Coagulation, Adhesion, Senescence and Cancer	38
Laser-Induced Axotomy of Human iPSC-Derived and Murine Primary Neurons Decreases Somatic Tau and AT8 Tau Phosphorylation: A Single-Cell Approach to Study Effects of Acute Axonal Damage	38
Genetic Discrimination of Grade 3 and Grade 4 Gliomas by Artificial Neural Network	37
Viruses and Mitochondrial Dysfunction in Neurodegeneration and Cognition: An Evolutionary Perspective	36
Fetal Brain Damage in Human Fetuses with Congenital Cytomegalovirus Infection: Histological Features and Viral Tropism	36

Can Environmental Enrichment Modulate Epigenetic Processes in the Central Nervous System Under Adverse Environmental Conditions? A Systematic Review	35
Correction: Proteomic and Cytokine Profiling in Plasma from Patients with Normal-Tension Glaucoma and Ocular Hypertension	34
Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders	34
Disease-Associated Neurotoxic Astrocyte Markers in Alzheimer Disease Based on Integrative Single-Nucleus RNA Sequencing	33
Inhibition of the Proteasome Regulator PA28 Aggravates Oxidized Protein Overload in the Diabetic Rat Brain	33
Klotho Upregulation via PPARγ Contributes to the Induction of Brain Ischemic Tolerance by Cerebral Ischemic Preconditioning in Rats	32
The Role of Retinal Dysfunction in Myopia Development	32
Tau Aggregation Inhibiting Peptides as Potential Therapeutics for Alzheimer Disease	32
Screening Plasma Proteins for the Putative Drug Targets for Carpal Tunnel Syndrome	31
Inhibition of UHRF1 Improves Motor Function in Mice with Spinal Cord Injury	31
Lanthanum Chloride Induces Axon Abnormality Through LKB1-MARK2 and LKB1-STK25-GM130 Signaling Pathways	30
Relevance of Thymic Stromal Lymphopoietin on the Pathogenesis of Glioblastoma: Role of the Neutrophil	29
AQP4 is an Emerging Regulator of Pathological Pain: A Narrative Review	29
Research Progress on the Immune-Inflammatory Mechanisms of Posttraumatic Epilepsy	28
Finding an Optimal Level of GDNF Overexpression: Insights from Dopamine Cycling	27
Iron Deposition in Parkinson’s Disease: A Mini-Review	27
Pesticide Exposure and Its Association with Parkinson’s Disease: A Case–Control Analysis	27
A Carboxy-terminal Smarcb1 Point Mutation Induces Hydrocephalus Formation and Affects AP-1 and Neuronal Signalling Pathways in Mice	27
Proteomic and Cytokine Profiling in Plasma from Patients with Normal-Tension Glaucoma and Ocular Hypertension	25
Correction: Upregulation of Glutamatergic Receptors in Hippocampus and Locomotor Hyperactivity in Aged Spontaneous Hypertensive Rat	25
Primary Hypothyroidism and Alzheimer’s Disease: A Tale of Two	25
Treadmill Running Regulates Adult Neurogenesis, Spatial and Non-spatial Learning, Parvalbumin Neuron Activity by ErbB4 Signaling	25
Dietary Fiber Modulates the Release of Gut Bacterial Products Preventing Cognitive Decline in an Alzheimer’s Mouse Model	24
The Mechanisms of Ferroptosis Under Hypoxia	24
The Provenance, Providence, and Position of Endothelial Cells in Injured Spinal Cord Vascular Pathology	24
Are mGluR2/3 Inhibitors Potential Compounds for Novel Antidepressants?	24
REST in the Road Map of Brain Development	23
Correction: Effect of Induction Time on the Proliferation and Differentiation of Induced Schwann‑Like Cells from Adipose‑Derived Stem Cells	23
The Role of Beta2-Microglobulin in Central Nervous System Disease	22
Pathophysiology, Diagnosis, Treatment, and Genetics of Carpal Tunnel Syndrome: A Review	22
ACh Transfers: Homeostatic Plasticity of Cholinergic Synapses	22
A Bibliometric Analysis of the Spatial Transcriptomics Literature from 2006 to 2023	22
Enlarged Perivascular Space and Index for Diffusivity Along the Perivascular Space as Emerging Neuroimaging Biomarkers of Neurological Diseases	21
Mechanism of Cone Degeneration in Retinitis Pigmentosa	21
The Role of Inflammatory Cascade and Reactive Astrogliosis in Glial Scar Formation Post-spinal Cord Injury	21
Neuroepigenetic Changes in DNA Methylation Affecting Diabetes-Induced Cognitive Impairment	21
Potential Prion Involvement in Long COVID-19 Neuropathology, Including Behavior	21
Navigating the Landscape of MANF Research: A Scientometric Journey with CiteSpace Analysis	21
Advanced Overview of Biomarkers and Techniques for Early Diagnosis of Alzheimer’s Disease	21
Human Oral Mucosa Stem Cells Increase Survival of Neurons Affected by In Vitro Anoxia and Improve Recovery of Mice Affected by Stroke Through Time-limited Secretion of miR-514A-3p	21
Prenatal Exposure to General Anesthesia Drug Esketamine Impaired Neurobehavior in Offspring	21
Neurological Consequences, Mental Health, Physical Care, and Appropriate Nutrition in Long-COVID-19	20
Activation of TRPV1 Channels Inhibits the Release of Acetylcholine and Improves Muscle Contractility in Mice	20
Synergistic Epistasis and Systems Biology Approaches to Uncover a Pharmacogenomic Map Linked to Pain, Anti-Inflammatory and Immunomodulating Agents (PAIma) in a Healthy Cohort	20
Neuromodulation Through Magnetic Fields Irradiation with AT-04 Improves Hyperalgesia in a Rat Model of Neuropathic Pain via Descending Pain Modulatory Systems and Opioid Analgesia	20
Hypoglycemia and Alzheimer Disease Risk: The Possible Role of Dasiglucagon	20
The Critical Role of RNA m6A Methylation in Gliomas: Targeting the Hallmarks of Cancer	20
Experiences Shape Hippocampal Neuron Morphology and the Local Levels of CRHR1 and OTR	19
Retraction Note: The Interplay of Tau Protein and β-Amyloid: While Tauopathy Spreads More Profoundly Than Amyloidopathy, Both Processes Are Almost Equally Pathogenic	19
Elabela, a Novel Peptide, Exerts Neuroprotective Effects Against Ischemic Stroke Through the APJ/miR-124-3p/CTDSP1/AKT Pathway	19

Liquid Biopsy in Low-Grade Glioma: A Systematic Review and a Proposal for a Clinical Utility Score	18
TIMP-3 Alleviates White Matter Injury After Subarachnoid Hemorrhage in Mice by Promoting Oligodendrocyte Precursor Cell Maturation	18
CircSKA3 is Associated With the Risk of Extracranial Artery Stenosis and Plaque Instability Among Ischemic Stroke Patients	17
Urine Proteomic Signatures of Mild Hypothermia Treatment in Cerebral Ischemia–Reperfusion Injury in Rats	17
Role of NAD+ and FAD in Ischemic Stroke Pathophysiology: An Epigenetic Nexus and Expanding Therapeutic Repertoire	16
Correction: Upregulation of miR-107 Inhibits Glioma Angiogenesis and VEGF Expression	16
Trehalose–Carnosine Prevents the Effects of Spinal Cord Injury Through Regulating Acute Inflammation and Zinc(II) Ion Homeostasis	15
A Pilot Study of Ex Vivo Human Prefrontal RNA Transcriptomics in Parkinson’s Disease	15
Roles of ApoE4 on the Pathogenesis in Alzheimer’s Disease and the Potential Therapeutic Approaches	15
Do Sleep Disturbances have a Dual Effect on Alzheimer’s Disease?	15
Uncovering the Significance of STEP61 in Alzheimer’s Disease: Structure, Substrates, and Interactome	15
Defensive and Emotional Behavior Modulation by Serotonin in the Periaqueductal Gray	15
The Circadian Clock of Polarized Microglia and Its Interaction with Mouse Brain Oscillators	14
Tripartite Motif Protein Family in Central Nervous System Diseases	14
Sleep Disorder Kleine–Levin Syndrome (KLS) Joins the List of Polygenic Brain Disorders Associated with Obstetric Complications	14
Phosphodiesterase-4 Inhibition in Parkinson’s Disease: Molecular Insights and Therapeutic Potential	14
Stem Cell-Derived Exosomal MicroRNAs as Novel Potential Approach for Multiple Sclerosis Treatment	14
Bidirectional Communication Between the Brain and Other Organs: The Role of Extracellular Vesicles	13
Neuroprotective Effect of miR-483-5p Against Cardiac Arrest-Induced Mitochondrial Dysfunction Mediated Through the TNFSF8/AMPK/JNK Signaling Pathway	13
The Neuroprotective Effects and Probable Mechanisms of Everolimus in a Rat Model of Intracerebral Hemorrhage	13
Rescuers from the Other Shore: Intercellular Mitochondrial Transfer and Its Implications in Central Nervous System Injury and Diseases	13
Quantitative Proteomics Characterization of the Effect and Mechanism of Trichostatin A on the Hippocampus of Type II Diabetic Mice	13
The Efficacy of Different Material Scaffold-Guided Cell Transplantation in the Treatment of Spinal Cord Injury in Rats: A Systematic Review and Network Meta-analysis	13
Methylmalonic Acid Impairs Cell Respiration and Glutamate Uptake in C6 Rat Glioma Cells: Implications for Methylmalonic Acidemia	13
Traumatic MicroRNAs: Deconvolving the Signal After Severe Traumatic Brain Injury	12
Microglial Metabolic Reprogramming: Emerging Insights and Therapeutic Strategies in Neurodegenerative Diseases	12
The Role of Mitophagy in Various Neurological Diseases as a Therapeutic Approach	12
BMECs Ameliorate High Glucose-Induced Morphological Aberrations and Synaptic Dysfunction via VEGF-Mediated Modulation of Glucose Uptake in Cortical Neurons	12
The Neuroprotective Effects of Administration of Methylprednisolone in Cardiopulmonary Resuscitation in Experimental Cardiac Arrest Model	12
The Role of MicroRNAs in Predicting the Neurological Outcome of Patients with Subarachnoid Hemorrhage: A Meta-analysis	12
Pearls and Pitfalls of Isolating Rat OPCs for In Vitro Culture with Different Methods	12
Elucidation of Site-Specific Ubiquitination on Chaperones in Response to Mutant Huntingtin	12
Substance P Reduces Infarct Size and Mortality After Ischemic Stroke, Possibly Through the M2 Polarization of Microglia/Macrophages and Neuroprotection in the Ischemic Rat Brain	12
Mitochondrial Dysfunction and Apoptosis in Brain Microvascular Endothelial Cells Following Blast Traumatic Brain Injury	11
Leptin Signaling Could Mediate Hippocampal Decumulation of Beta-Amyloid and Tau Induced by High-Intensity Interval Training in Rats with Type 2 Diabetes	11
Mild Hypothermia Alleviates Complement C5a-Induced Neuronal Autophagy During Brain Ischemia–Reperfusion Injury After Cardiac Arrest	11
Gut Microbial Alteration in MPTP Mouse Model of Parkinson Disease is Administration Regimen Dependent	11
Pharmacological Modulation of the Cytosolic Oscillator Affects Glioblastoma Cell Biology	11
Function of Long Noncoding RNAs in Glioma Progression and Treatment Based on the Wnt/β-Catenin and PI3K/AKT Signaling Pathways	11
Research Progress on the Role of Sirtuin 1 in Cerebral Ischemia	11
The Use of Stem Cells as a Potential Treatment Method for Selected Neurodegenerative Diseases: Review	11
Astroglial Connexin 43-Mediated Gap Junctions and Hemichannels: Potential Antidepressant Mechanisms and the Link to Neuroinflammation	10
High-Mobility Group Box 1 in Spinal Cord Injury and Its Potential Role in Brain Functional Remodeling After Spinal Cord Injury	10
Correction to: Lanthanum Chloride Induces Axon Abnormality Through LKB1-MARK2 and LKB1-STK25-GM130 Signaling Pathways	10
Extracellular Matrix Structure and Interaction with Immune Cells in Adult Astrocytic Tumors	10
Progressive Degeneration and Adaptive Excitability in Dopamine D1 and D2 Receptor-Expressing Striatal Neurons Exposed to HIV-1 Tat and Morphine	10
The Beneficial Clinical Effects of Teriflunomide in Experimental Autoimmune Myasthenia Gravis and the Investigation of the Possible Immunological Mechanisms	10
Zebrafish as a Model Organism for Studying Pathologic Mechanisms of Neurodegenerative Diseases and other Neural Disorders	10
Lactobacilli Cell-Free Supernatants Modulate Inflammation and Oxidative Stress in Human Microglia via NRF2-SOD1 Signaling	10
Acyl-Ghrelin Attenuates Neurochemical and Motor Deficits in the 6-OHDA Model of Parkinson’s Disease	10
Expression of CGRP in the Trigeminal Ganglion and Its Effect on the Polarization of Macrophages in Rats with Temporomandibular Arthritis	10
Candidate Key Proteins in Tinnitus: A Bioinformatic Study of Synaptic Transmission in Spiral Ganglion Neurons	10
Biosensors, Recent Advances in Determination of BDNF and NfL	10
Locus Coeruleus-Noradrenergic Neurons Regulate Stress Coping During Subchronic Exposure to Social Threats: A Characteristic Feature in Postpartum Female Mice	10
Neuroprotective Effect of Hydrogen Sulfide Subchronic Treatment Against TBI-Induced Ferroptosis and Cognitive Deficits Mediated Through Wnt Signaling Pathway	10
The Significant Role of microRNAs in Gliomas Angiogenesis: A Particular Focus on Molecular Mechanisms and Opportunities for Clinical Application	10
Ultrastructural Changes in Hippocampal Region CA1 Neurons After Exposure to Permissive Hypercapnia and/or Normobaric Hypoxia	10
Correction: In the Rat Midbrain, SG2NA and DJ-1 have Common Interactome, Including Mitochondrial Electron Transporters that are Comodulated Under Oxidative Stress	10
Identifying Genes that Affect Differentiation of Human Neural Stem Cells and Myelination of Mature Oligodendrocytes	9
Involvement of the G-Protein-Coupled Estrogen Receptor-1 (GPER) Signaling Pathway in Neurodegenerative Disorders: A Review	9
Visualizing Sphingosine-1-Phosphate Receptor 1(S1P1) Signaling During Central Nervous System De- and Remyelination	9
Unraveling the Neural Circuits: Techniques, Opportunities and Challenges in Epilepsy Research	9
Sleep and Oxidative Stress: Current Perspectives on the Role of NRF2	9
Retinal Changes in Parkinson’s Disease: A Non-invasive Biomarker for Early Diagnosis	9
Acute and Chronic Macrophage Differentiation Modulates TREM2 in a Personalized Alzheimer’s Patient-Derived Assay	9
Possible Implications of Obesity-Primed Microglia that Could Contribute to Stroke-Associated Damage	9
Nrf2 and Ferroptosis: A New Research Direction for Ischemic Stroke	9
Cognitive Impact of Neurotropic Pathogens: Investigating Molecular Mimicry through Computational Methods	9
Tubulin Cytoskeleton in Neurodegenerative Diseases–not Only Primary Tubulinopathies	9
Correction: CKLF1 Aggravates Focal Cerebral Ischemia Injury at Early Stage Partly by Modulating Microglia/Macrophage Toward M1 Polarization Through CCR4	9
Accelerated Extracellular Nucleotide Metabolism in Brain Microvascular Endothelial Cells in Experimental Hypercholesterolemia	9
Hypoxic White Matter Injury and Recovery After Reoxygenation in Adult Mice: Magnetic Resonance Imaging Findings and Histological Studies	9
Neuroprotective and Antioxidant Role of Oxotremorine-M, a Non-selective Muscarinic Acetylcholine Receptors Agonist, in a Cellular Model of Alzheimer Disease	9
In Vitro Models of Amyotrophic Lateral Sclerosis	9