Journal of Cerebral Blood Flow and Metabolism

(The TQCC of Journal of Cerebral Blood Flow and Metabolism is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research*567
Regulation of blood–brain barrier integrity by microglia in health and disease: A therapeutic opportunity206
Single-cell RNA-seq reveals the transcriptional landscape in ischemic stroke94
Potential therapeutic targets for intracerebral hemorrhage-associated inflammation: An update90
Benefits of exercise training on cerebrovascular and cognitive function in ageing74
Mitochondrial transfer from mesenchymal stem cells improves neuronal metabolism after oxidant injury in vitro: The role of Miro166
MiR-17-92 enriched exosomes derived from multipotent mesenchymal stromal cells enhance axon-myelin remodeling and motor electrophysiological recovery after stroke61
Tissue no-reflow despite full recanalization following thrombectomy for anterior circulation stroke with proximal occlusion: A clinical study61
Transcriptome analysis reveals sexual disparities in gene expression in rat brain microvessels56
Body mass index, time of day and genetics affect perivascular spaces in the white matter55
Collateral status contributes to differences between observed and predicted 24-h infarct volumes in DEFUSE 354
Causes and consequences of baseline cerebral blood flow reductions in Alzheimer’s disease54
Comparison of [11C]UCB-J and [18F]FDG PET in Alzheimer’s disease: A tracer kinetic modeling study48
Epitranscriptomic regulation by m6A RNA methylation in brain development and diseases46
Transcriptomic characterization of microglia activation in a rat model of ischemic stroke45
Transfer function analysis of dynamic cerebral autoregulation: A CARNet white paper 2022 update45
Mitochondrial quality control in acute ischemic stroke43
Neuroinflammatory responses of microglia in central nervous system trauma40
Genome-wide transcriptomic analysis of microglia reveals impaired responses in aged mice after cerebral ischemia40
Interleukin-4 improves white matter integrity and functional recovery after murine traumatic brain injury via oligodendroglial PPARγ37
Galectin-3 protects against ischemic stroke by promoting neuro-angiogenesis via apoptosis inhibition and Akt/Caspase regulation37
HDAC inhibition reduces white matter injury after intracerebral hemorrhage36
Hypoxia induces de novo formation of cerebral collaterals and lessens the severity of ischemic stroke36
Brain amyloid and vascular risk are related to distinct white matter hyperintensity patterns35
PET imaging of colony-stimulating factor 1 receptor: A head-to-head comparison of a novel radioligand, 11C-GW2580, and 11C-CPPC, in mouse models of acute and chronic neuroinflamm35
Altered glymphatic enhancement of cerebrospinal fluid tracer in individuals with chronic poor sleep quality35
Deep white matter hyperintensity is associated with the dilation of perivascular space35
Three-dimensional ultrastructure of the brain pericyte-endothelial interface35
Review of studies on dynamic cerebral autoregulation in the acute phase of stroke and the relationship with clinical outcome35
Cerebral oxygen extraction fraction (OEF): Comparison of challenge-free gradient echo QSM+qBOLD (QQ) with 15O PET in healthy adults34
Perfusion imaging-based tissue-level collaterals predict ischemic lesion net water uptake in patients with acute ischemic stroke and large vessel occlusion34
Regional hyperperfusion in older adults with objectively-defined subtle cognitive decline34
Achieving brain clearance and preventing neurodegenerative diseases—A glymphatic perspective33
Impact of sex andAPOEε4 on age-related cerebral perfusion trajectories in cognitively asymptomatic middle-aged and older adults: A longitudinal study33
Flow induces barrier and glycocalyx-related genes and negative surface charge in a lab-on-a-chip human blood-brain barrier model32
Change and predictive ability of circulating immunoregulatory lymphocytes in long-term outcomes of acute ischemic stroke32
Altered coupling of cerebral blood flow and functional connectivity strength in visual and higher order cognitive cortices in primary open angle glaucoma31
Role of perivascular and meningeal macrophages in outcome following experimental subarachnoid hemorrhage31
Role of endothelial nitric oxide synthase for early brain injury after subarachnoid hemorrhage in mice30
Binding characteristics of [18F]PI-2620 distinguish the clinically predicted tau isoform in different tauopathies by PET30
Hippocampal blood–brain barrier permeability is related to the APOE4 mutation status of elderly individuals without dementia29
Distinct features of brain perivascular fibroblasts and mural cells revealed by in vivo two-photon imaging29
D-Glucose uptake and clearance in the tauopathy Alzheimer’s disease mouse brain detected by on-resonance variable delay multiple pulse MRI28
Glymphatic pathways in the gyrencephalic brain28
Distinct peripheral blood monocyte and neutrophil transcriptional programs following intracerebral hemorrhage and different etiologies of ischemic stroke28
Binding of the synaptic vesicle radiotracer [11C]UCB-J is unchanged during functional brain activation using a visual stimulation task27
Simulation of oxygen transport and estimation of tissue perfusion in extensive microvascular networks: Application to cerebral cortex27
Integrative cerebral blood flow regulation in ischemic stroke26
Cerebrovascular phenotypes in mouse models of Alzheimer’s disease26
Opposed hemodynamic responses following increased excitation and parvalbumin-based inhibition26
Cerebrospinal fluid hemoglobin drives subarachnoid hemorrhage-related secondary brain injury26
Evaluation of the potassium channel tracer [18F]3F4AP in rhesus macaques25
How expensive is the astrocyte?25
Upregulation of ribosome complexes at the blood-brain barrier in Alzheimer's disease patients25
Cerebral arterial pulsatility is linked to hippocampal microvascular function and episodic memory in healthy older adults25
Potential therapeutic effects of Nrf2 activators on intracranial hemorrhage25
Glucagon-like peptide-1 receptor agonists as neuroprotective agents for ischemic stroke: a systematic scoping review24
Profiling cerebrovascular function in migraine: A systematic review and meta-analysis24
Microvascular changes associated with epilepsy: A narrative review24
Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development24
Understanding the brain uptake and permeability of small molecules through the BBB: A technical overview24
Intravenously delivered multilineage-differentiating stress enduring cells dampen excessive glutamate metabolism and microglial activation in experimental perinatal hypoxic ischemic encephalopathy24
Preclinical and clinical evidence of IGF-1 as a prognostic marker and acute intervention with ischemic stroke24
Mechanisms of the negative potential associated with Leão’s spreading depolarization: A history of brain electrogenesis24
Light sheet fluorescence microscopy of optically cleared brains for studying the glymphatic system23
Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue23
Aerobic exercise improves hippocampal blood flow for hypertensive Apolipoprotein E4 carriers23
Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission23
MicroRNA-30a regulates acute cerebral ischemia-induced blood–brain barrier damage through ZnT4/zinc pathway23
Microglia/macrophage polarization: Fantasy or evidence of functional diversity?23
4D flow MRI for non-invasive measurement of blood flow in the brain: A systematic review22
Low neuronal metabolism during isoflurane-induced burst suppression is related to synaptic inhibition while neurovascular coupling and mitochondrial function remain intact22
Evidence of cerebral hemodynamic dysregulation in middle-aged APOE ε4 carriers: The PREVENT-Dementia study22
Cardiac arrest and resuscitation activates the hypothalamic-pituitary-adrenal axis and results in severe immunosuppression22
Microglial phagocytosis and regulatory mechanisms after stroke22
In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET22
Neurovascular coupling dysfunction in end-stage renal disease patients related to cognitive impairment22
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion21
Targeting neutrophils as a novel therapeutic strategy after stroke21
Aging related impairment of brain microvascular bioenergetics involves oxidative phosphorylation and glycolytic pathways21
Linking cortical atrophy to white matter hyperintensities of presumed vascular origin21
Lenticulostriate artery combined with neuroimaging markers of cerebral small vessel disease differentiate the pathogenesis of recent subcortical infarction21
In vivo synaptic density relates to glucose metabolism at rest in healthy subjects, but is strongly modulated by regional differences21
CD36 deficiency reduces chronic BBB dysfunction and scar formation and improves activity, hedonic and memory deficits in ischemic stroke20
More than motor impairment: A spatiotemporal analysis of cognitive impairment and associated neuropathological changes following cortical photothrombotic stroke20
Choroid plexus function in neurological homeostasis and disorders: The awakening of the circadian clocks and orexins20
Intranasal delivery of interleukin-4 attenuates chronic cognitive deficits via beneficial microglial responses in experimental traumatic brain injury20
Optimized lactoferrin as a highly promising treatment for intracerebral hemorrhage: Pre-clinical experience20
Activation of astroglial CB1R mediates cerebral ischemic tolerance induced by electroacupuncture19
A line through the brain: implementation of human line-scanning at 7T for ultra-high spatiotemporal resolution fMRI19
Review of treatment and therapeutic targets in brain arteriovenous malformation19
Focally administered succinate improves cerebral metabolism in traumatic brain injury patients with mitochondrial dysfunction19
MRI-visible perivascular spaces in basal ganglia but not centrum semiovale or hippocampus were related to deep medullary veins changes19
Coupling between cerebrovascular oscillations and CSF flow fluctuations during wakefulness: An fMRI study19
Functional dynamics of dopamine synthesis during monetary reward and punishment processing19
Optical measurement of microvascular oxygenation and blood flow responses in awake mouse cortex during functional activation19
Integrative physiological assessment of cerebral hemodynamics and metabolism in acute ischemic stroke19
A meta-analysis of remote ischaemic conditioning in experimental stroke19
Effects of O-GlcNAcylation on functional mitochondrial transfer from astrocytes18
Hypoxemia increases blood-brain barrier permeability during extreme apnea in humans18
[11C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain18
Reliability of task-specific neuronal activation assessed with functional PET, ASL and BOLD imaging18
The meningeal lymphatic vessels and the glymphatic system: Potential therapeutic targets in neurological disorders18
Oligodendrocyte precursor cell transplantation promotes angiogenesis and remyelination via Wnt/β-catenin pathway in a mouse model of middle cerebral artery occlusion18
Differential regulation of oxidative stress, microbiota-derived, and energy metabolites in the mouse brain during sleep18
Glutamate levels and perfusion in pons during migraine attacks: A 3T MRI study using proton spectroscopy and arterial spin labeling18
Persistent neuroinflammation and behavioural deficits after single mild traumatic brain injury18
A new perspective on cerebrospinal fluid dynamics after subarachnoid hemorrhage: From normal physiology to pathophysiological changes18
Role of endothelium-pericyte signaling in capillary blood flow response to neuronal activity18
Neuronal GPR81 regulates developmental brain angiogenesis and promotes brain recovery after a hypoxic ischemic insult18
In vivo synaptic density loss correlates with impaired functional and related structural connectivity in Alzheimer’s disease17
Reliability and validity of the mean flow index (Mx) for assessing cerebral autoregulation in humans: A systematic review of the methodology17
Human brain functional MRS reveals interplay of metabolites implicated in neurotransmission and neuroenergetics17
Subarachnoid hemorrhage leads to early and persistent functional connectivity and behavioral changes in mice17
Metabolic underpinnings of activated and deactivated cortical areas in human brain17
Parkinson patients have a presynaptic serotonergic deficit: A dynamic deep brain stimulation PET study17
Reversal of neurovascular coupling in the default mode network: Evidence from hypoxia17
Complete inhibition of ABCB1 and ABCG2 at the blood–brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [11C]erlotinib17
Malignant astrocyte swelling and impaired glutamate clearance drive the expansion of injurious spreading depolarization foci17
Nrf2-BDNF-TrkB pathway contributes to cortical hemorrhage-induced depression, but not sex differences17
Remote ischemic conditioning enhances oxygen supply to ischemic brain tissue in a mouse model of stroke: Role of elevated 2,3-biphosphoglycerate in erythrocytes17
Female-specific neuroprotection after ischemic stroke by vitronectin-focal adhesion kinase inhibition17
TET3 regulates DNA hydroxymethylation of neuroprotective genes following focal ischemia16
A non-human primate model of stroke reproducing endovascular thrombectomy and allowing long-term imaging and neurological read-outs16
Hemodynamic and structural brain measures in high and low sedentary older adults16
A novel method of quantifying hemodynamic delays to improve hemodynamic response, and CVR estimates in CO2 challenge fMRI16
A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models16
Altered regional cerebral blood flow in obstructive sleep apnea is associated with sleep fragmentation and oxygen desaturation16
Test–retest variability and reference region-based quantification of 18F-BCPP-EF for imaging mitochondrial complex I in the human brain16
Cerebral blood flow measurements with 15O-water PET using a non-invasive machine-learning-derived arterial input function16
Cerebral ischemia in the developing brain16
Longitudinal monitoring of microglial/macrophage activation in ischemic rat brain using Iba-1-specific nanoparticle-enhanced magnetic resonance imaging16
Effects of increased intracranial pressure on cerebrospinal fluid influx, cerebral vascular hemodynamic indexes, and cerebrospinal fluid lymphatic efflux16
Heterogeneity and developmental dynamics of LYVE-1 perivascular macrophages distribution in the mouse brain16
RAGE-mediated T cell metabolic reprogramming shapes T cell inflammatory response after stroke16
Using arterial spin labeling to measure cerebrovascular reactivity in Moyamoya disease: Insights from simultaneous PET/MRI15
CSF lipocalin-2 increases early in subarachnoid hemorrhage are associated with neuroinflammation and unfavorable outcome15
Evaluation of [18F]-JNJ-64326067-AAA tau PET tracer in humans15
Effect of uric acid in animal models of ischemic stroke: A systematic review and meta-analysis15
Principles and requirements for stroke recovery science15
Assessing cerebral arterial pulse wave velocity using 4D flow MRI15
Genetic deletion of endothelial microRNA-15a/16-1 promotes cerebral angiogenesis and neurological recovery in ischemic stroke through Src signaling pathway15
Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease15
Pathophysiologic mechanisms of cerebral endotheliopathy and stroke due to Sars-CoV-215
Accumulation of PSA-NCAM marks nascent neurodegeneration in the dorsal hippocampus after neonatal hypoxic-ischemic brain injury in mice15
Inflammation-relevant microbiome signature of the stroke brain, gut, spleen, and thymus and the impact of exercise15
Longitudinal cortex-wide monitoring of cerebral hemodynamics and oxygen metabolism in awake mice using multi-parametric photoacoustic microscopy15
White matter network damage mediates association between cerebrovascular disease and cognition15
Longitudinal relation between blood pressure, antihypertensive use and cerebral blood flow, using arterial spin labelling MRI15
Cerebral perfusion is associated with blast exposure in military personnel without moderate or severe TBI15
Cell-specific activation of RIPK1 and MLKL after intracerebral hemorrhage in mice15
Hemispheric CSF volume ratio quantifies progression and severity of cerebral edema after acute hemispheric stroke15
A large portion of the astrocyte proteome is dedicated to perivascular endfeet, including critical components of the electron transport chain15
Inhibition of eIF5A hypusination pathway as a new pharmacological target for stroke therapy15
Choroid plexus perfusion and bulk cerebrospinal fluid flow across the adult lifespan14
Integrative analysis of the human brain mural cell transcriptome14
Efficient isolation of brain capillary from a single frozen mouse brain for protein expression analysis14
Arterial elasticity, endothelial function and intracranial vascular health: A multimodal MRI study14
Kinetics and 28-day test–retest repeatability and reproducibility of [11C]UCB-J PET brain imaging14
Assessment of microvascular rarefaction in human brain disorders using physiological magnetic resonance imaging14
High-altitude rodents have abundant collaterals that protect against tissue injury after cerebral, coronary and peripheral artery occlusion14
A review of bioeffects induced by focused ultrasound combined with microbubbles on the neurovascular unit14
Role of platelets in the pathogenesis of delayed injury after subarachnoid hemorrhage14
Cerebral haemodynamics with head position changes post-ischemic stroke: A systematic review and meta-analysis14
Poor venous outflow profiles increase the risk of reperfusion hemorrhage after endovascular treatment14
Deletion of ubiquitin ligase Nedd4l exacerbates ischemic brain damage14
Intracranial vessel wall lesions on 7T MRI and MRI features of cerebral small vessel disease: The SMART-MR study14
Selective intra-carotid blood cooling in acute ischemic stroke: A safety and feasibility study in an ovine stroke model14
Biomechanics and hemodynamics of stent-retrievers13
Detection of Alzheimer’s disease-related neuroinflammation by a PET ligand selective for glial versus vascular translocator protein13
Systematic review: Association between circulating microRNA expression & stroke13
Simultaneous nicotine and oral contraceptive exposure alters brain energy metabolism and exacerbates ischemic stroke injury in female rats13
Comparative vulnerability of PET radioligands to partial inhibition of P-glycoprotein at the blood-brain barrier: A criterion of choice?13
Cerebrovascular effects of glibenclamide investigated using high-resolution magnetic resonance imaging in healthy volunteers13
Can oligodendrocyte precursor cells be a therapeutic target for mitigating cognitive decline in cerebrovascular disease?13
Cerebroarterial pulsatility and resistivity indices are associated with cognitive impairment and white matter hyperintensity in elderly subjects: A phase-contrast MRI study13
Impact of meningeal uptake and partial volume correction techniques on [18F]MK-6240 binding in aMCI patients and healthy controls13
A functional cerebral endothelium is necessary to protect against cognitive decline12
The impact of native leptomeningeal collateralization on rapid blood flow recruitment following ischemic stroke12
Impaired capillary-to-arteriolar electrical signaling after traumatic brain injury12
Cerebral endothelial cell-derived small extracellular vesicles enhance neurovascular function and neurological recovery in rat acute ischemic stroke models of mechanical thrombectomy and embolic strok12
Noradrenaline released from locus coeruleus axons contracts cerebral capillary pericytes via α2 adrenergic receptors12
Cerebral critical closing pressure and resistance-area product: the influence of dynamic cerebral autoregulation, age and sex12
Metabolomic and transcriptional profiling reveals bioenergetic stress and activation of cell death and inflammatory pathways in vivo after neuronal deletion of NAMPT12
The central role of peripheral inflammation in ischemic stroke12
Long-term outcome of endovascular therapy for acute basilar artery occlusion12
Differential contribution of excitatory and inhibitory neurons in shaping neurovascular coupling in different epileptic neural states12
NMDA receptor ion channel activation detected in vivo with [18F]GE-179 PET after electrical stimulation of rat hippocampus12
Changes in synaptic density in the subacute phase after ischemic stroke: A11C-UCB-J PET/MR study12
Retinal capillary microvessel morphology changes are associated with vascular damage and dysfunction in cerebral small vessel disease12
Leptomeningeal collateral activation indicates severely impaired cerebrovascular reserve capacity in patients with symptomatic unilateral carotid artery occlusion12
Brain oxygen extraction fraction mapping in patients with multiple sclerosis12
The rise of pericytes in neurovascular research12
Protective effects of edaravone on white matter pathology in a novel mouse model of Alzheimer’s disease with chronic cerebral hypoperfusion12
Impact of blood pressure changes in cerebral blood perfusion of patients with ischemic Moyamoya disease evaluated by SPECT12
Cerebral metabolic rate of oxygen during transition from wakefulness to sleep measured with high temporal resolution OxFlow MRI with concurrent EEG12
Tenascin-C induction exacerbates post-stroke brain damage12