(The TQCC of
Hepatology is
75. The table below lists those papers that are above that threshold based on
CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)
| Article | Citations |
|---|
| A model to predict survival in patients with end-stage liver disease | 3469 |
| A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C | 2757 |
| Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome | 1907 |
| Liver transplantation for hepatocellular carcinoma: Expansion of the tumor size limits does not adversely impact survival | 1596 |
| Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference | 1483 |
| Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review and meta‐analysis | 997 |
| Global Perspectives on Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis | 825 |
| NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome | 807 |
| Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values | 787 |
| Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity | 779 |
| Increasing incidence and mortality of primary intrahepatic cholangiocarcinoma in the United States | 775 |
| Vascular invasion and histopathologic grading determine outcome after liver transplantation for hepatocellular carcinoma in cirrhosis | 723 |
| Chronic hepatitis B | 642 |
| A proposed system for the nomenclature of hepatitis C viral genotypes | 621 |
| The management of ascites in cirrhosis: Report on the consensus conference of the International Ascites Club | 602 |
| Sampling variability of liver fibrosis in chronic hepatitis C | 600 |
| Early virologic response to treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C | 596 |
| Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators | 584 |
| Increased risk of tumor seeding after percutaneous radiofrequency ablation for single hepatocellular carcinoma | 583 |
| Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis | 526 |
| Autoimmune hepatitis/sclerosing cholangitis overlap syndrome in childhood: A 16-year prospective study | 513 |
| Toll-Like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells | 492 |
| Gene expression of tumor necrosis factor [alpha ] and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients | 486 |
| Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: Results after 3 years of therapy | 485 |
| A randomized, double-blind trial comparing pegylated interferon alfa-2b to interferon alfa-2b as initial treatment for chronic hepatitis C | 480 |
| Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C | 446 |
| Estimating progression to cirrhosis in chronic hepatitis C virus infection | 440 |
| Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes | 425 |
| Hepatitis C virus kinetics during and immediately after liver transplantation | 423 |
| Hemodynamic response to pharmacological treatment of portal hypertension and long-term prognosis of cirrhosis | 395 |
| Persistent hepatitis B virus infection in subjects without hepatitis B surface antigen: Clinically significant or purely “occult”? | 394 |
| Hepatitis B e antigen–negative chronic hepatitis B | 384 |
| Cytokines and NASH: A pilot study of the effects of lifestyle modification and vitamin E | 375 |
| Sex Differences in Nonalcoholic Fatty Liver Disease: State of the Art and Identification of Research Gaps | 369 |
| Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression | 365 |
| Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice | 364 |
| Central role of PPARα-dependent hepatic lipid turnover in dietary steatohepatitis in mice | 362 |
| High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: A potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis | 360 |
| Hepatitis C Guidance 2019 Update: American Association for the Study of Liver Diseases–Infectious Diseases Society of America Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infe | 355 |
| Systemic, renal, and hepatic hemodynamic derangement in cirrhotic patients with spontaneous bacterial peritonitis | 350 |
| A multicenter United States—Canadian trial to assess lamivudine monotherapy before and after liver transplantation for chronic hepatitis B | 345 |
| Metallothionein‐1G facilitates sorafenib resistance through inhibition of ferroptosis | 344 |
| A prospective, randomized trial of butyl cyanoacrylate injection versus band ligation in the management of bleeding gastric varices | 332 |
| Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus | 321 |
| Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis | 319 |
| Long-Term outcomes of cirrhosis in nonalcoholic steatohepatitis compared with hepatitis C | 314 |
| Factors affecting liver fibrosis in human immunodeficiency virus–and hepatitis C virus–coinfected patients: Impact of protease inhibitor therapy | 311 |
| Geographic distribution of hepatitis B virus (HBV) genotype in patients with chronic HBV infection in Japan | 310 |
| A practice guideline on Wilson disease | 309 |
| Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-γ ligand rosiglitazone | 308 |
| Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region | 307 |
| Hepatocellular Carcinoma Is Associated With Gut Microbiota Profile and Inflammation in Nonalcoholic Fatty Liver Disease | 302 |
| Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection | 301 |
| Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy | 301 |
| Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: Apoptosis or necrosis? | 299 |
| The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR | 299 |
| Heterogeneity and plasticity of hepatocyte lineage cells | 296 |
| CXCR4 inhibition in tumor microenvironment facilitates anti‐programmed death receptor‐1 immunotherapy in sorafenib‐treated hepatocellular carcinoma in mice | 293 |
| Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats | 290 |
| A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C | 289 |
| Diagnosis and Management of Autoimmune Hepatitis in Adults and Children: 2019 Practice Guidance and Guidelines From the American Association for the Study of Liver Diseases | 289 |
| Hepatitis C virus infection and incident type 2 diabetes | 288 |
| Des-gamma carboxyprothrombin can differentiate hepatocellular carcinoma from nonmalignant chronic liver disease in american patients | 286 |
| Estimating Prevalence of Hepatitis C Virus Infection in the United States, 2013‐2016 | 286 |
| Diagnosis and Treatment of Alcohol‐Associated Liver Diseases: 2019 Practice Guidance From the American Association for the Study of Liver Diseases | 283 |
| Trends in survival of patients with hepatocellular carcinoma between 1977 and 1996 in the United States | 281 |
| Differential CD4+ and CD8+ T-cell responsiveness in hepatitis C virus infection | 280 |
| Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases | 276 |
| Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane | 270 |
| High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C | 268 |
| Efficacy and safety of pegylated (40-kd) interferon α-2a compared with interferon α-2a in noncirrhotic patients with chronic hepatitis C | 268 |
| Transforming growth factor β and the liver | 266 |
| Advances in bioartificial liver devices | 265 |
| Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B: New perspectives for immune therapy | 264 |
| Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition | 258 |
| Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice | 255 |
| Proliferative activity of intrahepatic colorectal metastases after preoperative hemihepatic portal vein embolization | 255 |
| The influence of human immunodeficiency virus coinfection on chronic hepatitis C in injection drug users: A long-term retrospective cohort study | 251 |
| Genetic polymorphisms and the progression of liver fibrosis: A critical appraisal | 250 |
| Resection of hepatocellular cancer ≤2 cm: Results from two Western centers | 248 |
| Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium | 242 |
| Unexpected Rapid Increase in the Burden of NAFLD in China From 2008 to 2018: A Systematic Review and Meta‐Analysis | 240 |
| Epidemiology of primary hepatic malignancies in U.S. children | 234 |
| Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats | 230 |
| Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver | 230 |
| Renal failure after upper gastrointestinal bleeding in cirrhosis: Incidence, clinical course, predictive factors, and short-term prognosis | 230 |
| Cellular localization and up-regulation of multidrug resistance–associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver | 230 |
| Long-term mortality and morbidity of transfusion-associated non-A, non-B, and type C hepatitis: A National Heart, Lung, and Blood Institute collaborative study | 228 |
| HIV coinfection shortens the survival of patients with hepatitis C virus-related decompensated cirrhosis | 224 |
| Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals | 223 |
| Prediction of treatment outcome in patients with chronic hepatitis C: Significance of baseline parameters and viral dynamics during therapy | 220 |
| Steroid-free chemotherapy decreases risk of hepatitis B virus (HBV) reactivation in HBV-carriers with lymphoma | 217 |
| Discrimination value of the new western prognostic system (CLIP score) for hepatocellular carcinoma in 662 Japanese patients | 217 |
| Neutrophil extracellular traps promote inflammation and development of hepatocellular carcinoma in nonalcoholic steatohepatitis | 216 |
| A meta-analysis of endoscopic variceal ligation for primary prophylaxis of esophageal variceal bleeding | 216 |
| HNF4: A central regulator of hepatocyte differentiation and function | 215 |
| Serum HBV DNA as a marker of efficacy during therapy for chronic HBV infection: Analysis and review of the literature | 214 |
| Antiangiogenic treatment with Sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats | 214 |
| Lamivudine treatment is beneficial in patients with severely decompensated cirrhosis and actively replicating hepatitis B infection awaiting liver transplantation: A comparative study using a matched, | 210 |
| Living donor liver transplantation for early hepatocellular carcinoma: A life-expectancy and cost-effectiveness perspective | 208 |
| Intraductal papillary neoplasia of the liver associated with hepatolithiasis | 207 |
| The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids | 207 |
| Cholangiocarcinoma: Current concepts and insights | 206 |
| Changes in WNT/β-catenin pathway during regulated growth in rat liver regeneration | 206 |
| Diagnosis and management of hemochromatosis | 205 |
| Transplantation for primary biliary cirrhosis: Retrospective analysis of 400 patients in a single center | 204 |
| MAdCAM-1 expressed in chronic inflammatory liver disease supports mucosal lymphocyte adhesion to hepatic endothelium (MAdCAM-1 in chronic inflammatory liver disease) | 202 |
| Comparison of two clinical scales for causality assessment in hepatotoxicity | 201 |
| Effect of ribavirin on hepatitis C viral kinetics in patients treated with pegylated interferon | 200 |
| Positron emission tomography with [18F]fluoro-2-deoxy-D-glucose for diagnosis and staging of bile duct cancer | 200 |
| Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C–dependent mechanisms in cholestatic rat | 199 |
| Inhibition of hepatitis B virus expression and replication by RNA interference | 198 |
| Expression and role of Bcl-xL in human hepatocellular carcinomas | 198 |
| Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: Evidence for Akt inhibition in celecoxib-induced apoptosis | 197 |
| c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration | 196 |
| The role of Smad3 in mediating mouse hepatic stellate cell activation | 196 |
| Primary sclerosing cholangitis in children: A long-term follow-up study | 195 |
| Treatment of hepatitis C infection in injection drug users | 195 |
| HBV DNA persistence 10 years after liver transplantation despite successful anti-HBS passive immunoprophylaxis | 194 |
| Expression of mRNA for DNA methyltransferases and methyl-CpG–binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human hepatocarcinogenesis | 194 |
| Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9 | 192 |
| Short-term prognosis in critically ill patients with cirrhosis assessed by prognostic scoring systems | 190 |
| Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa-2b and ribavirin | 188 |
| The normal liver harbors the vitamin D nuclear receptor in nonparenchymal and biliary epithelial cells | 187 |
| Mother-to-infant transmission of hepatitis C virus | 185 |
| Mouse A6–positive hepatic oval cells also express several hematopoietic stem cell markers | 184 |
| Which patients with cirrhosis should undergo endoscopic screening for esophageal varices detection? | 184 |
| Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury | 184 |
| Kinetics of the immune response during HBV and HCV infection | 183 |
| Hepatitis C virus infection in a community in the Nile Delta: Risk factors for seropositivity | 181 |
| Disrupted signaling and inhibited regeneration in obese mice with fatty livers: Implications for nonalcoholic fatty liver disease pathophysiology | 181 |
| Complementary and alternative medicine in chronic liver disease | 180 |
| Drug-induced liver injury: Mechanisms and test systems | 180 |
| Analysis of hepatitis B viral load decline under potent therapy: Complex decay profiles observed | 180 |
| Ductular Reaction in Liver Diseases: Pathological Mechanisms and Translational Significances | 180 |
| Risk factors for primary biliary cirrhosis in a cohort of patients from the United States | 178 |
| A model to predict severe HCV-related disease following liver transplantation | 177 |
| Role of hepatitis B, C, and D viruses in dual and triple infection: Influence of viral genotypes and hepatitis B precore and basal core promoter mutations on viral replicative interference | 177 |
| Differentiation of embryonic stem cells into hepatocytes: Biological functions and therapeutic application | 173 |
| Protective immune response to hepatitis C virus in chimpanzees rechallenged following clearance of primary infection | 173 |
| A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liver | 172 |
| Association of nonalcoholic fatty liver disease with subclinical myocardial remodeling and dysfunction: A population‐based study | 172 |
| Detection of functionally altered hepatitis C virus-specific CD4+ T cells in acute and chronic hepatitis C | 171 |
| Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases | 171 |
| Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors | 170 |
| Angiogenesis in chronic inflammatory liver disease | 170 |
| Durability of serologic response after lamivudine treatment of chronic hepatitis B | 168 |
| Determinants for sustained HBeAg response to lamivudine therapy | 167 |
| Long-term follow-up of interferon alfa treatment in chinese patients with chronic hepatitis B infection: The effect on hepatitis B e antigen seroconversion and the development of cirrhosis-related com | 167 |
| Long-Term suppression of hepatitis B e antigen-negative chronic hepatitis B by 24-month interferon therapy | 166 |
| Treatment strategy for small hepatocellular carcinoma: Comparison of long-term results after percutaneous ethanol injection therapy and surgical resection | 166 |
| Increased cancer risk in a cohort of 230 patients with hereditary hemochromatosis in comparison to matched control patients with non–iron-related chronic liver disease | 166 |
| Spontaneous bacterial peritonitis in asymptomatic outpatients with cirrhotic ascites | 165 |
| Prevalence of HBV precore/core promoter variants in the United States | 163 |
| ADAM12 in human liver cancers: TGF-β-regulated expression in stellate cells is associated with matrix remodeling | 162 |
| The role of liver biopsy in chronic hepatitis C | 161 |
| Prevalence and significance of hepatitis B virus (HBV) pre-S mutants in serum and liver at different replicative stages of chronic HBV infection | 161 |
| Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis | 159 |
| Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirus-mediated antisense targeting | 158 |
| Interorgan ammonia and amino acid metabolism in metabolically stable patients with cirrhosis and a TIPSS | 158 |
| Immune checkpoint blockade in hepatocellular carcinoma: Current progress and future directions | 157 |
| Mouse Models of Nonalcoholic Steatohepatitis: Toward Optimization of Their Relevance to Human Nonalcoholic Steatohepatitis | 157 |
| Circular RNA MAT2B Promotes Glycolysis and Malignancy of Hepatocellular Carcinoma Through the miR‐338‐3p/PKM2 Axis Under Hypoxic Stress | 155 |
| Cyclins and cyclin-dependent kinases: Comparative study of hepatocellular carcinoma versus cirrhosis | 154 |
| Familial intrahepatic cholestasis 1: Studies of localization and function | 154 |
| Detection of antimitochondrial autoantibodies in immunofluorescent AMA-negative patients with primary biliary cirrhosis using recombinant autoantigens | 154 |
| Dual Programmed Death Receptor‐1 and Vascular Endothelial Growth Factor Receptor‐2 Blockade Promotes Vascular Normalization and Enhances Antitumor Immune Responses in Hepatocellular Carcinoma | 154 |
| Portal cavernoma-associated cholangiopathy: A clinical and MR cholangiography coupled with MR portography imaging study | 153 |
| Human CD96 Correlates to Natural Killer Cell Exhaustion and Predicts the Prognosis of Human Hepatocellular Carcinoma | 152 |
| Sal-like protein 4 (SALL4), a stem cell biomarker in liver cancers | 151 |
| Noninvasive Tests Accurately Identify Advanced Fibrosis due to NASH: Baseline Data From the STELLAR Trials | 151 |
| Viral dynamics and response differences in HCV-infected African American and white patients treated with IFN and ribavirin | 150 |
| Autoimmune hepatitis with incidental histologic features of bile duct injury | 150 |
| Randomized trial comparing albumin and saline in the prevention of paracentesis-induced circulatory dysfunction in cirrhotic patients with ascites | 150 |
| 17‐Beta Hydroxysteroid Dehydrogenase 13 Is a Hepatic Retinol Dehydrogenase Associated With Histological Features of Nonalcoholic Fatty Liver Disease | 150 |
| Establishment, characterization, and long-term maintenance of cultures of human fetal hepatocytes | 149 |
| Hepatitis C virus infection and needle exchange use among young injection drug users in San Francisco | 149 |
| The Natural History of Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: Data From the Simtuzumab Trials | 149 |
| Viral and clinical factors associated with the fulminant course of hepatitis A infection | 148 |
| Increased extracellular matrix remodeling is associated with tumor progression in human hepatocellular carcinomas | 148 |
| Human bile contains MicroRNA-laden extracellular vesicles that can be used for cholangiocarcinoma diagnosis | 147 |
| Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis | 146 |
| Acute hepatitis C | 145 |
| Prevalence of naturally occurring surface gene variants of hepatitis B virus in nonimmunized surface antigen–negative Chinese carriers | 145 |
| Long‐Term Risk of Hepatocellular Carcinoma in HCV Patients Treated With Direct Acting Antiviral Agents | 145 |
| NGM282 Improves Liver Fibrosis and Histology in 12 Weeks in Patients With Nonalcoholic Steatohepatitis | 145 |
| Interleukin 6 is important for survival after partial hepatectomy in mice | 143 |
| Pseudocapillarization and associated energy limitation in the aged rat liver | 142 |
| Adenosine monophosphate[ndash ]activated protein kinase mediates the protective effects of ischemic preconditioning on hepatic ischemia-reperfusion injury in the rat | 141 |
| Predicting the prognosis of chronic liver disease: An evolution from child to MELD | 140 |
| RNA expression in the early characterization of hepatotoxicants in Wistar rats by high-density DNA microarrays | 140 |
| Long noncoding RNA TSLNC8 is a tumor suppressor that inactivates the interleukin‐6/STAT3 signaling pathway | 140 |
| Graft dysfunction mimicking autoimmune hepatitis following liver transplantation in adults | 139 |
| Preconditioning protects against systemic disorders associated with hepatic ischemia-reperfusion through blockade of tumor necrosis factor–induced P-selectin up-regulation in the rat | 139 |
| Differential regulation of TGF-β signal in hepatic stellate cells between acute and chronic rat liver injury | 138 |
| Interleukin 10 polymorphisms as predictors of sustained response in antiviral therapy for chronic hepatitis C infection | 137 |
| The biliary epithelium gives rise to liver progenitor cells | 137 |
| Hepatic gene expression in histologically progressive nonalcoholic steatohepatitis | 136 |
| Long-term histologic and virologic outcomes of acute self-limited hepatitis B | 136 |
| Angiopoietins and Tie-2 expression in angiogenesis and proliferation of human hepatocellular carcinoma | 136 |
| The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS‐9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis | 136 |
| Mechanisms of benzarone and benzbromarone-induced hepatic toxicity | 135 |
| Identification of differentially expressed genes in hepatocellular carcinoma with cDNA microarrays | 134 |
| Fecal Microbial Transplant Capsules Are Safe in Hepatic Encephalopathy: A Phase 1, Randomized, Placebo‐Controlled Trial | 134 |
| Sex is a major determinant of CYP3A4 expression in human liver | 132 |
| Sickle cell hepatopathy | 131 |
| Etoposide prevents apoptosis in mouse liver with ?-galactosamine/lipopolysaccharide-induced fulminant hepatic failure resulting in reduction of lethality | 130 |
| Intrahepatic Cholangiocarcinoma: Continuing Challenges and Translational Advances | 129 |
| Inhibition of microsomal triglyceride transfer protein: Another mechanism for drug-induced steatosis in mice | 128 |
| Malaria sporozoites actively enter and pass through rat Kupffer cells prior to hepatocyte invasion | 128 |
| ADAPT: An Algorithm Incorporating PRO‐C3 Accurately Identifies Patients With NAFLD and Advanced Fibrosis | 128 |
| Cigarette smoking and hepatic lesions in patients with chronic hepatitis C | 127 |
| Caspase activation correlates with the degree of inflammatory liver injury in chronic hepatitis C virus infection | 127 |
| Impact of Sustained Virologic Response with Direct‐Acting Antiviral Treatment on Mortality in Patients with Advanced Liver Disease | 127 |
| Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis | 126 |
| Conditional tetracycline-regulated expression of TGF-β1 in liver of transgenic mice leads to reversible intermediary fibrosis | 124 |
| Antibiotic prophylaxis in cirrhosis: Good and bad | 124 |
| HLA class II genotype influences the type of liver injury in drug-induced idiosyncratic liver disease | 124 |
| Candidate biomarkers for the diagnosis and prognosis of drug‐induced liver injury: An international collaborative effort | 124 |
| Propranolol plus placebo versus propranolol plus isosorbide-5-mononitrate in the prevention of a first variceal bleed: A double-blind RCT | 123 |
| Gas exchange mechanism of orthodeoxia in hepatopulmonary syndrome | 123 |
| Salivary gland progenitor cells induced by duct ligation differentiate into hepatic and pancreatic lineages | 122 |
| Peripheral blood mononuclear cell expression of toll-like receptors and relation to cytokine levels in cirrhosis | 122 |
| Gene therapy of orthotopic hepatocellular carcinoma in rats using adenovirus coding for interleukin 12 | 122 |
| Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases | 121 |
| Involvement of p21WAF1/Cip1, p27Kip1, and p18INK4c in troglitazone-induced cell-cycle arrest in human hepatoma cell lines | 121 |
| Safety and efficacy of oral entecavir given for 28 days in patients with chronic hepatitis B virus infection | 121 |
| Up-regulated expression of the receptor for advanced glycation end products in cultured rat hepatic stellate cells during transdifferentiation to myofibroblasts | 121 |
| A North American Expert Opinion Statement on Sarcopenia in Liver Transplantation | 121 |
| Spatiotemporal expression of angiogenesis growth factor receptors during the revascularization of regenerating rat liver | 120 |
| Mitochondrial oxidative injury and energy metabolism alteration in rat fatty liver: Effect of the nutritional status | 120 |
| Prospective study on anti-hepatitis C virus–positive patients with persistently normal serum alanine transaminase with or without detectable serum hepatitis C virus RNA | 120 |
| Hepatitis C, cryoglobulinemia, and cirrhosis: A meta-analysis | 119 |
| Sinusoidal ultrastructure evaluated during the revascularization of regenerating rat liver | 119 |
| Redefining Cirrhotic Cardiomyopathy for the Modern Era | 119 |
| Hepatic copper metabolism: Insights from genetic disease | 118 |
| Pharmacokinetics and pharmacodynamic action of budesonide in early- and late-stage primary biliary cirrhosis | 118 |
| EBP50, a β-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinoma | 118 |
| Week 48 resistance surveillance in two phase 3 clinical studies of adefovir dipivoxil for chronic hepatitis B | 118 |
| Causality assessment versus guilt-by-association in drug hepatotoxicity | 118 |
| The geographical distribution of primary biliary cirrhosis in a well-defined cohort | 117 |
| Liraglutide, Sitagliptin, and Insulin Glargine Added to Metformin: The Effect on Body Weight and Intrahepatic Lipid in Patients With Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver Disease | 117 |
| Coronavirus Disease 2019 Hangover: A Rising Tide of Alcohol Use Disorder and Alcohol‐Associated Liver Disease | 117 |
| PTFE-covered stents improve TIPS patency in Budd-Chiari syndrome | 115 |
| Halofuginone to prevent and treat thioacetamide-induced liver fibrosis in rats | 115 |
| Outcome of liver transplantation in patients with diabetes mellitus: A case-control study | 115 |
| CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease | 114 |
| Mechanisms for sensitization to TNF-induced apoptosis by acute glutathione depletion in murine hepatocytes | 113 |
| Early change in bilirubin levels is an important prognostic factor in severe alcoholic hepatitis treated with prednisolone | 113 |
| Detoxification of reactive oxygen species by a nonpeptidyl mimic of superoxide dismutase cures acetaminophen-induced acute liver failure in the mouse | 112 |
| Modulation of Insulin Resistance in Nonalcoholic Fatty Liver Disease | 112 |
| Hepatitis C virus infection in the general population: A community-based study in West Bengal, India | 111 |
| SEN virus infection and its relationship to transfusion-associated hepatitis | 111 |
| Changing Trends in Etiology‐Based and Ethnicity‐Based Annual Mortality Rates of Cirrhosis and Hepatocellular Carcinoma in the United States | 111 |
| Blocking Triggering Receptor Expressed on Myeloid Cells‐1‐Positive Tumor‐Associated Macrophages Induced by Hypoxia Reverses Immunosuppression and Anti‐Programmed Cell Death Ligand 1 Resistance in Live | 111 |
| Occult hepatitis B virus infection: A hidden menace? | 110 |
| Role of the hepatocyte nuclear factor 4α in control of the pregnane X receptor during fetal liver development | 110 |
| A sequential study of serum bacterial DNA in patients with advanced cirrhosis and ascites | 110 |
| Endoplasmic Reticulum Stress Causes Liver Cancer Cells to Release Exosomal miR‐23a‐3p and Up‐regulate Programmed Death Ligand 1 Expression in Macrophages | 110 |
| Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling | 109 |
| Primary lymphoma of the liver: Clinical-pathological features and relationship with HCV infection in French patients | 109 |
| Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion | 108 |
| MHC class II-expressing hepatocytes function as antigen-presenting cells and activate specific CD4 T lymphocyutes | 107 |
| The mitochondrial permeability transition contributes to acute ethanol-induced apoptosis in rat hepatocytes | 107 |
| Validation and refinement of survival models for liver retransplantation | 106 |
| Massive liver growth in mice induced by systemic interleukin 6 administration | 106 |
| Antiviral activity of clevudine [?-FMAU, (1-(2-fluoro-5-methyl-β, ?-arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks (Mar | 106 |
| Serum mitochondrial biomarkers and damage-associated molecular patterns are higher in acetaminophen overdose patients with poor outcome | 106 |
| Effects of blood volume restitution following a portal hypertensive–related bleeding in anesthetized cirrhotic rats | 105 |
| Ursodeoxycholic acid administration in patients with cholestasis of pregnancy: Effects on primary bile acids in babies and mothers | 105 |
| Octreotide in hepatorenal syndrome: A randomized, double-blind, placebo-controlled, crossover study | 104 |
| The Role of Innate Immune Cells in Nonalcoholic Steatohepatitis | 104 |
| Serum Hepatitis B Virus RNA: A New Potential Biomarker for Chronic Hepatitis B Virus Infection | 104 |
| Probiotic Lactobacillus rhamnosus GG Prevents Liver Fibrosis Through Inhibiting Hepatic Bile Acid Synthesis and Enhancing Bile Acid Excretion in Mice | 104 |
| A Noncoding Regulatory RNAs Network Driven by Circ‐CDYL Acts Specifically in the Early Stages Hepatocellular Carcinoma | 104 |
| All liver recipients benefit from the protocol 10-year liver biopsies | 103 |
| Genetic variation in the interleukin
-28B
gene is not associated with fibrosis progression in patients with chronic hepatitis C and known date of infection | 102 |
| Deficiency of thrombin activatable fibrinolysis inhibitor in cirrhosis is associated with increased plasma fibrinolysis | 102 |
| Differential expression of cyclooxygenase-2 (COX-2) in human bile duct epithelial cells and bile duct neoplasm | 102 |
| Intracellular signaling pathways involved in acetaldehyde-induced collagen and fibronectin gene expression in human hepatic stellate cells | 102 |
| Bile acid feeding increased proliferative activity and apical bile acid transporter expression in both small and large rat cholangiocytes | 102 |
| Protracted, but not acute, hepatitis A virus infection is strongly associated with HLA-DRB1*1301, a marker for pediatric autoimmune hepatitis | 102 |
| Induction of catalase, alpha, and microsomal glutathione S-transferase in CYP2E1 overexpressing HepG2 cells and protection against short-term oxidative stress | 102 |
| A pilot study of therapeutic vaccination with envelope protein E1 in 35 patients with chronic hepatitis C | 101 |
| Novel CD4+ and CD8+ T-cell determinants within the NS3 protein in subjects with spontaneously resolved HCV infection | 100 |
| TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells | 100 |
| Cholangiocyte‐Derived Exosomal Long Noncoding RNA H19 Promotes Hepatic Stellate Cell Activation and Cholestatic Liver Fibrosis | 100 |
| The processing and utilization of hepatocyte growth factor/scatter factor following partial hepatectomy in the rat | 99 |
| Promoter polymorphism of the CD14 endotoxin receptor gene as a risk factor for alcoholic liver disease | 99 |
| Incidence and Mortality of Acute‐on‐Chronic Liver Failure Using Two Definitions in Patients with Compensated Cirrhosis | 99 |
| Caspase inhibition reduces apoptotic death of cryopreserved porcine hepatocytes | 98 |
| Inhibition of intrahepatic metastasis of human hepatocellular carcinoma by Rho-associated protein kinase inhibitor Y-27632 | 98 |
| Endothelial cell–mediated uptake of a hepatitis B virus: A new concept of liver targeting of hepatotropic microorganisms | 98 |
| Activation of retinoic X receptor and peroxisome proliferator–activated receptor-γ inhibits nitric oxide and tumor necrosis factor-α production in rat Kupffer cells | 98 |
| Burden of Illness and Economic Model for Patients With Nonalcoholic Steatohepatitis in the United States | 98 |
| The relationship of in vivo31P MR spectroscopy to histology in chronic hepatitis C | 97 |
| Combination of interferon induction therapy and ribavirin in chronic hepatitis C | 97 |
| Hereditary thrombophilia as a cause of Budd-Chiari syndrome: A study from Western India | 97 |
| Activation of caspases occurs downstream from radical oxygen species production, Bcl-xL down-regulation, and early cytochrome C release in apoptosis induced by transforming growth factor β in rat feta | 97 |
| Rapid diagnosis of spontaneous bacterial peritonitis by use of Reagent Strips | 96 |
| Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection | 96 |
| A novel long noncoding RNA Lnc‐HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism | 96 |
| Long noncoding RNA H19 interacts with polypyrimidine tract‐binding protein 1 to reprogram hepatic lipid homeostasis | 96 |
| A Positive Feedback Loop Between Cancer Stem‐Like Cells and Tumor‐Associated Neutrophils Controls Hepatocellular Carcinoma Progression | 96 |
| The kidney plays a major role in the hyperammonemia seen after simulated or actual GI bleeding in patients with cirrhosis | 95 |
| Propranolol for the prevention of first esophageal variceal hemorrhage: A lifetime commitment? | 95 |
| Prevalence and risk factors for hepatitis C virus infection at an Urban veterans administration medical center | 95 |
| The Role of Senescence in the Development of Nonalcoholic Fatty Liver Disease and Progression to Nonalcoholic Steatohepatitis | 95 |
| Protein kinase C–dependent distribution of the multidrug resistance protein 2 from the canalicular to the basolateral membrane in human HepG2 cells | 94 |
| Changes in Hepatic Venous Pressure Gradient Predict Hepatic Decompensation in Patients Who Achieved Sustained Virologic Response to Interferon‐Free Therapy | 93 |
| Intestinal Fungal Dysbiosis and Systemic Immune Response to Fungi in Patients With Alcoholic Hepatitis | 93 |
| Diagnosing fibrosis in hepatitis C: Is the pendulum swinging from biopsy to blood tests? | 92 |
| Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes | 92 |
| Lusutrombopag for the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing Invasive Procedures (L‐PLUS 2) | 92 |
| Hepatic osteodystrophy | 92 |
| PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas | 91 |
| Clinical Impact of Genomic Diversity From Early to Advanced Hepatocellular Carcinoma | 91 |
| FUN14 Domain‐Containing 1–Mediated Mitophagy Suppresses Hepatocarcinogenesis by Inhibition of Inflammasome Activation in Mice | 90 |
| Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol‐Induced Liver Damage, Steatosis, and Inflammation in Mice | 90 |
| Normal hepatocytes correct serum bilirubin after repopulation of Gunn rat liver subjected to irradiation/partial resection | 90 |
| Interferon alfa regulated gene expression in patients initiating interferon treatment for chronic hepatitis C | 89 |
| Influence of ethnicity in the outcome of hepatitis C virus infection and cellular immune response | 89 |
| High rates of hepatocellular carcinoma in cirrhotic patients with high liver cell proliferative activity | 89 |
| The risk of liver and bile duct cancer in patients with chronic viral hepatitis, alcoholism, or cirrhosis | 89 |
| Performance of chronic kidney disease epidemiology collaboration creatinine-cystatin C equation for estimating kidney function in cirrhosis | 89 |
| Dysregulated Autophagy and Lysosome Function Are Linked to Exosome Production by Micro‐RNA 155 in Alcoholic Liver Disease | 89 |
| Vitamin E Improves Transplant‐Free Survival and Hepatic Decompensation Among Patients With Nonalcoholic Steatohepatitis and Advanced Fibrosis | 89 |
| Hepatitis C virus and liver disease: Global transcriptional profiling and identification of potential markers | 88 |
| Simtuzumab for Primary Sclerosing Cholangitis: Phase 2 Study Results With Insights on the Natural History of the Disease | 88 |
| Restoration of cerebral blood flow autoregulation and reactivity to carbon dioxide in acute liver failure by moderate hypothermia | 87 |
| Peginterferon alpha-2b is safe and effective in HBeAg-positive chronic hepatitis B patients with advanced fibrosis | 87 |
| Sorafenib Induces Pyroptosis in Macrophages and Triggers Natural Killer Cell–Mediated Cytotoxicity Against Hepatocellular Carcinoma | 87 |
| Longitudinal Assessment of Three Serum Biomarkers to Detect Very Early‐Stage Hepatocellular Carcinoma | 87 |
| Visualization of early events in tumor formation of eGFP-transfected rat colon cancer cells in liver | 86 |
| Characterization of the mouse bile salt export pump overexpressed in the baculovirus system | 86 |
| Global changes in interleukin-6–dependent gene expression patterns in mouse livers after partial hepatectomy | 86 |
| Alcohol abstinence in patients surviving an episode of alcoholic hepatitis: Prediction and impact on long‐term survival | 86 |
| Microdissection-based allelotyping discriminates de novo tumor from intrahepatic spread in hepatocellular carcinoma | 85 |
| Nitric oxide-mediated cytoprotection of hepatocytes from glucose deprivation-induced cytotoxicity: Involvement of heme oxygenase-1 | 85 |
| The Role of Complement in Liver Injury, Regeneration, and Transplantation | 85 |
| Moderate alcohol consumption increases oxidative stress in patients with chronic hepatitis C | 84 |
| Keratin mutation in transgenic mice predisposes to Fas but not TNF-induced apoptosis and massive liver injury | 84 |
| Ezrin-radixin-moesin–binding phosphoprotein 50 is expressed at the apical membrane of rat liver epithelia | 84 |
| Notch receptor expression in adult human liver: A possible role in bile duct formation and hepatic neovascularization | 84 |
| Continuous renal replacement therapy is associated with reduced serum ammonia levels and mortality in acute liver failure | 84 |
| Nonalcoholic Steatohepatitis Is Associated With Liver‐Related Outcomes and All‐Cause Mortality in Chronic Hepatitis B | 84 |
| American Association for the Study of Liver Diseases Expert Panel Consensus Statement: Vaccines to Prevent Coronavirus Disease 2019 Infection in Patients With Liver Disease | 84 |
| Alcohol-induced liver injury in mice lacking Cu, Zn-superoxide dismutase | 83 |
| RNA helicase DEAD box protein 5 regulates Polycomb repressive complex 2/Hox transcript antisense intergenic RNA function in hepatitis B virus infection and hepatocarcinogenesis | 83 |
| Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liver | 82 |
| Adjuvant intra-arterial injection of iodine-131–labeled lipiodol after resection of hepatocellular carcinoma | 82 |
| Antibiotic‐Associated Disruption of Microbiota Composition and Function in Cirrhosis Is Restored by Fecal Transplant | 82 |
| Prospective evaluation of ursodeoxycholic acid withdrawal in patients with primary sclerosing cholangitis | 82 |
| Proteomic analysis and molecular characterization of tissue ferritin light chain in hepatocellular carcinoma | 82 |
| Autoimmune overlap syndromes | 81 |
| A role of autoantibody-mediated platelet destruction in thrombocytopenia in patients with cirrhosis | 81 |
| Combination of interferon and ribavirin in chronic hepatitis C: Re-treatment of nonresponders to interferon | 81 |
| Oxidative stress in fatty livers of obese Zucker rats: Rapid amelioration and improved tolerance to warm ischemia with tocopherol | 81 |
| Inhibitory role of peroxisome proliferator-activated receptor gamma in hepatocarcinogenesis in mice and in vitro | 81 |
| Impaired IRS-1/PI3-kinase signaling in patients with HCV: A mechanism for increased prevalence of type 2 diabetes | 80 |
| Hepatitis C virus–like particles induce virus-specific humoral and cellular immune responses in mice | 80 |
| Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma | 80 |
| Diabetes Is Associated With Increased Risk of Hepatocellular Carcinoma in Patients With Cirrhosis From Nonalcoholic Fatty Liver Disease | 80 |
| Hepatocyte‐Specific β‐Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes | 79 |
| Molecular identification of bacterial 16S ribosomal RNA gene in liver tissue of primary biliary cirrhosis: Is Propionibacterium acnes involved in granuloma formation? | 79 |
| Thromboelastography‐Guided Blood Component Use in Patients With Cirrhosis With Nonvariceal Bleeding: A Randomized Controlled Trial | 79 |
| Induced hyperammonemia alters neuropsychology, brain MR spectroscopy and magnetization transfer in cirrhosis | 78 |
| Gene expression associated with interferon alfa antiviral activity in an HCV replicon cell line | 78 |
| Indomethacin prevents the development of experimental ammonia-induced brain edema in rats after portacaval anastomosis | 78 |
| Hepatic and intestinal cytochrome P450 3A activity in cirrhosis: Effects of transjugular intrahepatic portosystemic shunts | 78 |
| Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth | 78 |
| Mechanism of retarded liver regeneration in plasminogen activator-deficient mice: Impaired activation of hepatocyte growth factor after Fas-mediated massive hepatic apoptosis | 78 |
| Alcoholic hepatitis: Translational approaches to develop targeted therapies | 78 |
| Age and Sex but Not ATP7B Genotype Effectively Influence the Clinical Phenotype of Wilson Disease | 78 |
| Adult living donor liver transplantation: The hepatologist's perspective | 77 |
| Alterations in tight junctions differ between primary biliary cirrhosis and primary sclerosing cholangitis | 77 |
| Interferon and ribavirin for patients with chronic hepatitis C who did not respond to previous interferon therapy: A meta-analysis of controlled and uncontrolled trials | 77 |
| Nonheavy Drinking and Worsening of Noninvasive Fibrosis Markers in Nonalcoholic Fatty Liver Disease: A Cohort Study | 77 |
| Long Noncoding RNA p53‐Stabilizing and Activating RNA Promotes p53 Signaling by Inhibiting Heterogeneous Nuclear Ribonucleoprotein K deSUMOylation and Suppresses Hepatocellular Carcinoma | 77 |
| Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression | 76 |
| Repopulation of rat liver by fetal hepatoblasts and adult hepatocytes transduced ex vivo with lentiviral vectors | 76 |
| Ursodeoxycholic acid therapy and the risk of colorectal adenoma in patients with primary biliary cirrhosis: An observational study | 76 |
| Signal pathway involved in the development of hypoxic preconditioning in rat hepatocytes | 76 |
| Targeting dexamethasone to Kupffer cells: Effects on liver inflammation and fibrosis in rats | 76 |
| Serum Metabolites as Diagnostic Biomarkers for Cholangiocarcinoma, Hepatocellular Carcinoma, and Primary Sclerosing Cholangitis | 76 |
| Hepatitis C virus reinfection and superinfection among treated and untreated participants with recent infection | 76 |
| Membrane cholesterol but not putative receptors mediates anandamide-induced hepatocyte apoptosis | 75 |
| Maintenance therapy with ribavirin in patients with chronic hepatitis C who fail to respond to combination therapy with interferon alfa and ribavirin | 75 |
| Outcome of hospital care of liver disease associated with hepatitis C in the United States | 75 |
| Expression of cyclooxygenase-2 promotes the release of matrix metalloproteinase-2 and -9 in fetal rat hepatocytes | 75 |
| Earlier expression of the transcription factor HFH-11B diminishes induction of p21CIP1/WAF1 levels and accelerates mouse hepatocyte entry into S-phase following carbon tetrachloride liver injury | 75 |
| Antiplatelet therapy and the risk of hepatocellular carcinoma in chronic hepatitis B patients on antiviral treatment | 75 |
| Terlipressin Is Superior to Noradrenaline in the Management of Acute Kidney Injury in Acute on Chronic Liver Failure | 75 |