Biomedical Chromatography

Papers
(The TQCC of Biomedical Chromatography is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
The Isolation and Separation of Hydrophobic Bioactive Peptide Obtained From Tilapia ( Oreochromis niloticus 47
A Validated UPLC‐MS/MS Method for Monitoring Temozolomide and Perillyl Alcohol Metabolites in Biological Matrices: Insights From a Preclinical Pharmacokinetic Study39
Development of a simultaneous quantification method of imatinib and sunitinib and their main metabolites and its application in patients with gastrointestinal stromal tumor30
Identification of Dendrobium devonianum Samples With Different Growth Years Based on Active Ingredients and Deduction of the Chemical Structural Transformation28
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Development of simultaneous quantitative analytical method for metabolites of hexosamine biosynthesis pathway in lung cancer cells using ultra‐high‐performance liquid chromatography‐tandem mass spectr26
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Preparation of 5‐hydroxymethylfurfural from Schisandra chinensis (Turcz.) Baill by high‐speed counter‐current chromatography: Comparison of conventional and consecutive separation24
Mango peel extracts and mangiferin chromatographic Fourier‐transform infrared correlation with antioxidant, antidiabetic, and advanced glycation end product inhibitory potentials using in silico model23
Development of stability‐indicating method for separation and characterization of benidipine forced degradation products using LC–MS/MS22
Green Ultra‐Fast UPLC–MS/MS Method for Enasidenib Quantification in HLMs Matrix With the Metabolic Stability Assessment: In Silico Study for Structural Alerts, ADME Characteristics and Metaboslic Labi22
Interference Assessment for High‐Performance Liquid Chromatography HbA1c Assays21
Assessment of Apalutamide Metabolic Stability in HLMs Matrix Using a Sensitive and Fast UPLC‐MS/MS Method: In Silico Screening for Toxicity Alerts and Metabolic Lability21
Separation and Identification of Impurity of Chlortetracycline Hydrochloride Not Included in the European Pharmacopoeia20
Simultaneous Determination of Four Active Ingredients in Snow Chrysanthemum by HPLC With Determination of Its Antioxidant Activity in Vitro20
Pioneering Human Plasma Detection of Haloperidol With 5‐pg/mL Sensitivity via Refined Sample Preparation and Advanced LC–MS/MS20
Characterization and Analytical Method Validation for Potential Impurities of a Merchantability Drug Substance Fluoxetine HCl20
In vivo detection of the epimer metabolites of sweroside via ultra‐performance liquid chromatography time‐of‐flight mass spectrometry combined with DNPH derivatization19
Evaluation of various polysaccharide‐based stationary phases for enantioseparation of chloro‐containing derivatives in normal phase liquid chromatography18
A Robust LC‐MS/MS Bioanalytical Strategy for Simultaneous Quantification of Tramadol HCl and Dexketoprofen Trometamol and Its Use in Pharmacokinetic Studies17
An LC–MS/MS Method for the Quantitation of Metabolites M9, M12, and M20 of Bexicaserin in Human Cerebrospinal Fluid17
Matrix effect in bioanalytical assay development using supercritical fluid chromatography‐mass spectrometry16
Validation of an HPLC‐UV for Apixaban Stability‐Indicating Study15
Integrative LC–MS/MS, Bioinformatics, and Molecular Dynamics Reveal Multitarget Antioxidant Mechanisms of Bushen Huoxue Decoction in Intervertebral Disc Degeneration15
An UHPLC–QTOF–MS‐based strategy for systematic profiling of chemical constituents and associated in vivo metabolites of a famous traditional Chinese medicine formula, Yinchenhao decoction15
The pharmacokinetics and tissue distribution of curcumin following inhalation administration in rats—A comparative analysis with oral and intravenous routes15
Detection and identification of imperatorin metabolites in rat, dog, monkey, and human liver microsomes by ultra‐high‐performance liquid chromatography combined with high‐resolution mass spectrometry 15
Residue levels and risk assessment of acetamiprid–pyridaben mixtures in cabbage under various open field conditions14
LC–MS/MS Quantification and Solvent‐Exposure Modeling Reveal a Mismatch Between Linker Exposure and Payload Release in Wild‐Type Trastuzumab‐VC‐PABC‐MMAE in Rat Plasma14
Evaluation of lipophilicity and drug‐likeness of donepezil‐like compounds using reversed‐phase thin‐layer chromatography14
Pharmacokinetics and Metabolism of ARV‐393, a BCL6 PROTAC Degrader, in Dogs by UPLC–MS/MS and UPLC‐Q‐Exactive Orbitrap‐HRMS14
RP‐HPLC method development, validation and pharmacokinetic applicability in preclinical evaluation of rhein treated with novel diacerein eutectics14
Development of a joint derivatization protocol for the unequivocal identification of the monosaccharide composition in four dendrobium polysaccharides and free monosaccharide by GC–MS14
Lipidomics reveals the serum profiles of pediatric allergic rhinitis and its severity14
Metabolomics Reveals the Mechanism of American Ginseng in Alleviating Insulin Resistance by Reversing Metabolic Disorders in HepG2 Cells14
Screening for α‐glucosidase inhibitors from Selaginella uncinata based on the ligand fishing combined with ultra‐high‐performance liquid chromatography–quadrupole time‐of‐flight–tandem m14
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Multimodal Metabolomics Analysis Reveals That Classic Decoction Mitigates Myocardial Ischemia‐Induced Damage by Modulating Energy and Branched‐Chain Amino Acid Metabolism13
The Effect of Kaempferol on Valsartan Metabolism In Vitro and In Vivo and the Underlying Mechanism With Cytochrome p450 Using UPLC‐MS/MS13
Determination of three C18‐oxygenated steroids in adrenal lesion segments in primary aldosteronism by super‐selective adrenal venous sampling and LC/ESI–MS/MS13
Integrated Experimental and Computational Evaluation of the Gut‐Targeted Anticoccidial Potential of Agaricus bisporus Methanolic Extract13
Metabolic Profiling of 5‐Methoxypinocembroside and Pharmacokinetics Study of Its Major Metabolite Alpinetin in Rat Plasma by UHPLC–MS13
Screening of Antiaging Active Components of Morinda officinalis and the Mechanism of Enhanced Efficacy After Salt‐Steaming13
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Chromatographic analysis and antioxidant potency of the crude extract of Xanthium spinosum in various fractions12
Study on Quality Markers for Hypoglycemic Effects of Moringa oleifera Leaves by the Integration of12
Pharmacokinetic and pharmacodynamic herb–drug interactions of common over‐the‐counter pain medications12
Development and validation of a stability‐indicating ultra‐high‐performance liquid chromatography method for the estimation of ibrutinib and trace‐level quantification of related substances using qual12
Delineation of prototypical degradation mechanism, characterization of unknown degradation impurities by liquid chromatography–quadrupole‐time‐of‐flight–tandem mass spectrometry and stability‐indicati12
Development and validation of novel RP‐HPLC method for midostaurin determination using analytical quality by design approach from regulatory perspective and determination of major degradation compound11
Potential role of the methanolic extract for Olea europaea (stem and leaves) on sporulation of Eimeria papillata oocysts: In vitro study11
A Comprehensive Review of Analytical Techniques for Doxycycline and Its Metabolites11
Spectroscopic characterization and pharmacokinetic evaluation of amorphous solid dispersions of glibenclamide for bioavailability enhancement in Wistar rats11
Therapeutic potential of Shaoyao Gancao Decoction in mitigating anti‐tuberculosis drug‐induced liver injury through Nrf‐2/HO‐1/NF‐κB signaling11
Online preconcentration and determination of five alkaloids in Yangxinshi tablet by large‐volume sample stacking and micelle to solvent stacking in cyclodextrin‐modified electrokinetic chromatography11
Comprehensive Evaluation of Growth Period Variations in Bioactive Properties and Phytochemical Profiles of Aesculus chinensis Bge Seeds and Leaves11
Application of Proteomics in the Study of Toxicology and Toxic Markers of Traditional Chinese Medicines11
Comparative phytochemical study of methanolic and ethanolic extracts of Thymus linearis and their antibacterial and antioxidant potential11
Revealing the Anti‐Inflammatory Mechanisms of Zingiber officinale Roscoe Through Network Pharmacol11
Insight gained via ultra‐performance liquid chromatography tandem mass spectrometry‐based metabolomics: Protective effect of Artemisia argyi H.Lév. & Vaniot essential oil on lipopolysacchar11
Development and validation of gas chromatography with electron capture detection method using QuEChERS for pesticide residue determination in cucumber10
Development and Validation of Sensitive RP‐HPLC Bioanalytical Method of Diclofenac Sodium and Its Predictive In‐Silico Physiologically Based Pharmacokinetic Modeling in Hepatic and Renal Impairment10
Development and Validation of a UPLC‐MS/MS Method for the Determination of Apalutamide in Human Plasma and Its Application in a Bioequivalence Study10
Investigation of the therapeutic effect of Hedan tablets on high‐fat diet‐induced obesity in rats by GC–MS technology and 16S ribosomal RNA gene sequencing10
Lateal Flow Immunoassay for Sensitive and Rapid Detection of Methylisomiroestrol in Pueraria candollei Using Monoclonal Antibody9
The Complex Formation Between Ginsenosides and Glutathione Utilized in Cosmetics to Promote Transdermal Absorption and Mask the Bad Odor of Glutathione9
Comparative analysis of the liver‐protective effects of raw and stir‐fried semen of Hovenia dulcis in rats via gas chromatography–mass spectrometry–based serum metabolomic profiling 9
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Process Optimization of Stir‐Fried Inonotus hispidus Based on the Box–Behnken Design‐Response Surface Method and the Component Variations During the Stir‐Frying Process9
Supercritical fluid chromatography for milligram preparation of enantiomers9
Trace Analysis of Genotoxic Impurity 3‐Amino‐N‐Nitrosopiperidine in Alogliptin Benzoate by Ultra‐Sensitive Liquid Chromatography Tandem Mass Spectrometry9
Dissipation and Risk Assessment of a Combination Product of Chlorantraniliprole + Abamectin and Spirotetramat in Pomegranate Fruit and Juice9
Dissipation Kinetics, Risk Assessment, and Decontamination Studies of Pyridalyl in Cabbage by GC–MS/MS9
Si Miao San relieves hyperuricemia by regulating intestinal flora9
Simultaneous Determination of Buspirone, Alprazolam, Clonazepam, Diazepam, and Lorazepam by LC‐MS/MS: Evaluation of Greenness Using AGREE Tool9
Rapid Analysis of Chemical Constituents in Blachia pentzii Leaves and Predictive Analysis of the Pharmacological Effects for Treatment of Rheumatoid Arth9
A Simple Rapid HPLC‐UV Method for Assessing C‐Terminal Arginine Content in Darbepoetin Alfa9
Chromatography in Preparative/Industrial Scale Separation of Enantiomeric Mixtures8
Development and Validation of a Stability‐Indicating RS HPLC Method for Leuprolide Acetate and Its Related Substances: Characterization of Degradation Products With LC‐MS8
Investigating the in vivo effect of Tribulus terrestris extract in middle cerebral artery occlusion rats using LC–MS‐based metabolomics combined with molecular docking8
Assessment of remdesivir and its nucleoside metabolite in beagle dogs and healthy humans by liquid chromatography coupled with triple quadrupole mass spectrometry8
Supported liquid extraction combined with liquid chromatography tandem mass spectrometry for the quantitative analysis of a TLR7 agonist imiquimod LFX453 in plasma at low picograms per milliliter: Met8
A pharmacokinetics interaction study of antiplatelet agents aspirin and clopidogrel combined with dl‐3‐n‐butylphthalide in rats by liquid chromatography–tandem mass spectrometry8
Serum and urine metabolomics based on UPLC–QTOF/MS reveal the effect and potential mechanism of “schisandra–evodia” herb pair in the treatment of Alzheimer's disease8
Farfarae Flos Mitigates Cigarette Smoking‐Induced Lung Inflammation by Regulating the Lysophosphatidylcholine Biosynthesis and Tryptophan Metabolism8
Determination of Schaftoside and Isoschaftoside in Rat Plasma Utilizing UPLC‐MS/MS8
An LC–ESI–MS/MS assay for the therapeutic drug monitoring of 15 antiseizure medications in plasma of children with epilepsy8
Identification of the Absorbed Constituents and Metabolites of Shenyanshu Tablets in Rat Plasma by Ultrahigh‐Performance Liquid Chromatography Coupled With Quadrupole Time‐of‐Flight Mass Spectrometry8
Serum metabolome analysis reveals medicinal fungi Phellinus igniarius ameliorated type 2 diabetes mellitus indications in rats via modulation of amino acid and carbohydrate metabolism8
Amelioration of Guishao Yigong Decoction on Colorectal Cancer Through the Integration of 16S rRNA Sequencing and Fecal Metabolomics8
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Bioanalytical UHPLC–MS/MS Method for Quantification of Terbinafine in Ungual Delivery Studies8
Optimization of Environmentally Sustainable UPLC‐PDA Method Using Box–Behnken for Simultaneous Quantifying Curcumin and Candesartan Cilexetil in On‐Demand Formulation for Treatment of Brain Ischemic I8
A liquid chromatography–tandem mass spectrometry method development for the quantification of favipiravir drug and its related impurities in rat plasma and its application to pharmacokinetic studies8
Spectrum–effect relationship between HPLC fingerprint and hypoglycemic of litchi leaves (Litchi chinensis Sonn) in vitro8
UPLC Multiwavelength Quantification and PLS‐DA Reveal Stir‐Baking Degree‐Dependent Marker Dynamics in Paeoniae Radix Alba8
Pharmacokinetics, Mass Balance, and Metabolism of [ 14 C]TPN729, a Selective and Potent Phosphodiesterase Type 5 Inhibitor in Humans8
Sustainable RP‐HPLC Method Development Using AQbD Approach for Simultaneous Estimation of Valganciclovir Hydrochloride and Piperine‐Loaded Lipid Nanoparticles8
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Beyond the Database: Integration of Network Pharmacology and UHPLC‐QTOF‐MS/MS to Reveal the Neuroprotective Potential of Bai Mi Decoction in Stroke Therapy8
Simultaneous quantitation of urine aldosterone and tetrahydroaldosterone in healthy Chinese subjects using a validated LC–MS/MS method8
Comparative Chromatographic Analysis of Amino Acids in the Seeds of Three Nigella L. Representatives7
Quantitation of tazemetostat in human plasma using liquid chromatography–tandem mass spectrometry7
Identifying of Anticoagulant Ingredients From Moutan Cortex Based on Spectrum‐Effect Relationship Analysis Combined With GRA, PLS, and SVM Algorithms7
Anticoccidial Effects of Tirmania nivea Extract and In Silico Evaluation of Its Phytochemicals Against Eimeria 7
LC–MS/MS Assay for Simultaneous Quantification of Dual‐Targeting 1,5‐Diaryl‐1,2,4‐Triazole Sulfonamides (WA11–13) in Human Plasma7
Metabolic Profile In Vivo and Potential Mechanisms of Danggui Jianzhong Decoction Against Gastric Ulcer by Ultra‐High‐Performance Quadrupole Time‐of‐Flight Mass Spectrometry Combined With Network Phar7
Human plasma ricinine quantification by LC–HRMS after micro‐solid‐phase elution7
Metabolism of the Total Flavonoid Extract of Lithocarpus litseifolius (Hance) Chun in Rats7
Determination of 59 Psychotropic Drugs, Including Antipsychotics, Antidepressants, Antiepileptics, Anti‐Alcohol Abuse Drugs, Anti‐ADHD Drugs, and Their Metabolites in Urine Using LC–MS/MS for Medicati7
Development and Validation of a Rapid and Simple UHPLC–MS/MS Method for the Determination of Colchicine in Human Plasma7
UPLC Estimate of Sofosbuvir and Ledipasvir Utilizing Greenness Tool in Conjunction With an Analytical Quality by Design7
A selective, sensitive and fast LC–MS/MS method for cabotegravir quantification in rat plasma and pharmacokinetic investigations7
An effective LC–MS method for the simultaneous determination of a potential anti‐rheumatoid arthritis drug, carboxyamidotriazole, and its major metabolite in rat plasma7
Metabolite Identification of Huangqi Guizhi Wuwu Granules in Rat Urine and Feces Based on Ultra–High‐Performance Liquid Chromatography With Quadrupole Time‐of‐Flight Mass Spectrometry7
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Impact of introducing a new biological matrix into a validated bioanalytical method: Focus on matrix protein content7
Quality Difference Analysis of Pomegranate Peels Based on Multidimensional Fingerprint With Chemical Pattern Recognition7
LC–MS/MS method for quick detection of vonoprazan fumarate in human plasma: Development, validation and its application to a bioequivalence study7
Phytochemical profile and pharmacological potential of Withania somnifera whole plant extracts7
Metabolomics and serum pharmacochemistry revealed the preventive mechanism of Gushudan in kidney‐yang‐deficiency‐syndrome rats7
Effect of Fuzheng Pill on Liver Cancer via the Mitochondrial Apoptosis Pathway7
Comparative Metabolic Profiling and Anti‐Inflammatory Evaluation of Ceiba speciosa and 7
Innovative UPLC technique for concurrent quantification of etofenamate and benzyl nicotinate in the presence of methylparaben and benzyl alcohol in their topical cream: Greens, white, and Six Sigma me7
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Quantitative Determination and Stability of Trace Levels of Oxytocin in Human and Rhesus Macaque Urine by LC–MS/MS7
The delivery of nanoparticles improves the pharmacokinetic properties of celecoxib to open a therapeutic window for oral administration of insoluble drugs7
Simultaneous quantification of icaritin and its novel 3‐methylcarbamate prodrug in rat plasma using HPLC–MS/MS and its application to pharmacokinetic study6
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Development and Validation of the Novel, Fast Bioanalytical LC‐MS/MS Technique for the Simultaneous Estimation of Sotorasib and Ondansetron: Application to In Vivo Pharmacokinetic Assessments6
First Establishment of LC–MS/MS Method for Quantitative Analysis of Pharmacokinetics and Tissue Distribution of Trilobatin—Comparison of Three Administration Modes6
Identification of the metabolites of nimbolide in rat by liquid chromatography combined with quadrupole/orbitrap mass spectrometry6
Advances in Analytical Strategies for Precise Quantification of Topoisomerase Inhibitors: Current Trends and Future Directions6
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A Method for Analysis of Free and Total Ropivacaine in Dog Plasma Using UHPLC–MS/MS6
A novel LC–MS/MS approach to [19F]‐alfatide and alfatide for application in preclinical pharmacokinetics6
A validated stability‐indicating reversed‐phase‐UPLC method for simultaneous estimation of promethazine hydrochloride, methylparaben, propylparaben and sodium benzoate assay of cough suppressant and a6
Mechanistic Insights Into the Anti‐Constipation Potential of Xiaogan Jianwei Formula: Integration of HPLC‐Q‐TOF MS/MS, Network Pharmacology, In Vivo Validation, and Gut Microbiota6
Development and Validation of HPTLC Method for Estimation of Podophyllotoxin in Crude Extract, Isolated Podophyllotoxin and Marketed Mother Tincture of 6
Network pharmacology study on fermented soybeans for the prevention of Alzheimer's disease in older individuals6
Green method by National Environmental Methods Index and Eco‐Scale Assessment for evaluation of gatifloxacin‐based product by HPLC6
Investigation of the Potential Material Basis and Mechanism of Astragali Radix Against Adriamycin‐Induced Nephropathy Model Rat by 1H NMR and MS‐Based Untargeted Metabolomics Analysis6
Quantification of Trans‐ and Cis‐Vitamin K1 Isomers in Human Plasma by a Rapid and Sensitive LC–MS/MS Method With Surrogate Matrix6
Development of Mobile‐Phase Buffers and Evaluation of Analytical Performance for HbA1c Assays6
Metabolomic analysis of the sera of patients with the long‐term inhalation of caffeine‐sodium benzoate using LC–MS6
Study on the material basis of Zhujing pill in treating fundus lesions through component analysis and network pharmacology6
Comparative analysis of six aconitine‐type alkaloids in decocting extracts between the different processed Fuzi (Aconiti Lateralis Radix praeparata) and its pharmacokinetic behavior in rats by HPLC‐MS6
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Screening and characterization of cosmetic efficacy components of Terminalia chebula based on biological activity‐guided methodology6
Detection of Pesticide Residues in Fruits and Vegetables Involving Different Chromatographic Techniques (LC–MS/MS, GC–MS/MS, GC and HPLC)6
Simultaneous Quantification of Filgotinib and Its Active Metabolite in Human Plasma Using Liquid Chromatography–Tandem Mass Spectrometry: Validation and Clinical Application6
Discovery of Q‐Markers of Mudan Granules by Chemical Profile, Pharmacokinetics, Neuroprotective Effect Evaluation, and Network Pharmacology6
Integrative In Vivo and Transcriptomics‐Guided In Silico Profiling of Citrus sinensis Phytochemica6
The Continued Mismeasurement of Plasma Serotonin: A Systematic Review6
Widely Targeted Metabolomics Reveals the Bioactive Metabolites and Antioxidant Activities of Chinese Yam (Dioscorea opposita Thunb.) Peel6
Noval Selective Ligand‐Extraction of Bioactive Components in Complex Natural Products Applying Immobilized Multi‐Target Magnetic Beads6
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Spectrum–effect relationship study between ultra‐high‐performance liquid chromatography fingerprints and anti‐hepatoma effect in vitro of Cnidii Fructus6
Degradation pathways and impurity profiling of the anticancer drug apalutamide by HPLC and LC–MS/MS and separation of impurities using Design of Experiments6
Rapid analysis of components in Qizhiweitong tablets and plasma after oral administration in rats by UPLC–Q‐TOF–MS/MS based on a self‐developed database6
Unraveling the Mechanisms of Modified Si Miao San in Treating Gouty Arthritis: Network Pharmacology and Experimental Validation6
The JAK2V617F mutation and childhood type1 diabetic nephropathy?6
Dispersive liquid–liquid microextraction and Monte Carlo simulation of margin of safety for octocrylene, EHMC, 2ES, and homosalate in sunscreens6
LC–MS/MS determination of HY072808, a novel candidate for treating atopic dermatitis, and its active metabolite: Application to a first‐in‐human pharmacokinetic study6
A Simple and Sensitive LC‐MS/MS Method for the Determination of Mobocertinib and Its Metabolite Desmethyl‐Mobocertinib in Human Plasma and Its Application to Clinical Pharmacokinetic Study6
A Simple Eco‐Friendly Stability‐Indicating HPLC Method for Determination of NETILMICIN in Bulk and Ophthalmic Solution6
Study on Quality Evaluation of Processed Cimicifuga Rhizoma Based on UPLC Fingerprint and Chemometrics6
A Simple, Sensitive, and Stable LC–MS/MS Method for the Simultaneous Determination and Pharmacokinetic Study of Dapagliflozin and Its Metabolite D3OG in Human Plasma6
Retention behaviour of analytes in reversed‐phase high‐performance liquid chromatography—A review5
Metabolic profiling of emodin drug‐induced liver injury and silybin treatment in rats using ultra‐performance liquid chromatography‐quadrupole‐time‐of‐flight‐mass spectrometry: A metabolomic and mecha5
LC–HRMS methods for the quantification of two artemisinin drugs and their metabolites in rat blood and plasma5
Fluorescent immunochromatography of vancomycin in plasma: A rapid and sensitive quantitative analysis5
Integrated pharmacokinetics of Huangqi Jianzhong Tang in normal and chronic atrophic gastritis rats5
Non‐Targeted Metabolomics Analysis of Metabolite Differences in Inocutis tamaricis Under Different Culture Conditions5
Simultaneous determination and quality evaluation of 16 compounds in Ligustri Lucidi Fructus covering different regions and processed products using ultra‐high‐performance liquid chromatography‐mass s5
Mechanism of Compound Xinyi Nasal Drops in the Treatment of Allergic Rhinitis Through STAT3/IL‐17A/NF‐κB Signaling Pathway Based on Network Pharmacology and Experimental Verification5
Assessment of metabolic stability and pharmacokinetics by LC–MS/MS and establishment of the safe dose of IMID‐2, a novel anticancer molecule under drug discovery5
Bioanalytical Tandem Mass Spectrometry Method for Precise Measurement of Tranexamic Acid in Human Plasma With Unveiling Methodological Advancement: Green Assessment With Advanced Metrics5
HPLC and GC–MS–based metabolic profiles and in vivo anticonvulsant, sedative, and antinociceptive potentials of truffles Tirmania nivea and Tirmania pinoyi hydromethanolic extracts in mi5
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Bone and periosteum protein analysis via tandem mass tag quantitative proteomics in pediatric patients with osteomyelitis5
Characterization of Liposomal and Free Aqueous Extracts of Ceratonia siliqua : Evaluation of Pheno5
Correction to “Exploring the Pharmacological Mechanisms of Xiaochaihu Tang in Treating Postmenopausal Osteoporosis: A Study Based on Network Pharmacology and Experimental Validation”5
From Chemical Discrepancy to Mechanistic Insight: UPLC‐MS, Bioinformatics, and In Vivo Studies on the Anti‐Brain Aging Effects of Polygalae Radix and Its Processed Products5
Effects of voriconazole and fluconazole on the pharmacokinetics of almonertinib in rats by UPLC–MS/MS5
Identification and Quantitation of Cardiac Hypertrophy Inhibitory Components in Trichosanthis Pericarpium Injection Based on UHPLC‐QE‐MS and Spectrum–Eff5
Application of QbD based approach in development and validation of RP‐HPLC method for simultaneous estimation of methotrexate and baicalin in dual‐drug‐loaded liposomes5
A simple and sensitive liquid chromatography triple quadrupole mass spectrometry method for the determination of XL092 in monkey plasma and its application to pharmacokinetic study5
Development and validation of a liquid chromatography coupled with tandem mass spectrometry method for determining total and unbound pamiparib in human plasma and brain tumors5
Method validation, dissipation and residue status of fluopicolide and fosetyl‐aluminium in citrus using a rapid extraction method coupled with ultra‐performance liquid chromatography–tandem mass spect5
Pharmacokinetics and bioequivalence studies of fluvoxamine maleate tablets in healthy Chinese subjects5
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Quantitation of Tucatinib, a Novel Tyrosine Kinase Inhibitor in Dried Blood Spot (DBS) With LC‐ESI‐MS/MS: Application to a Pharmacokinetic Study in Mice5
Mechanism of Jinteng Qingbi granules in the treatment of rheumatoid arthritis using metabolomics analysis5
Multiple Reaction Monitoring LC‐MS/MS Quantification of N‐Nitrosamine Drug Substance Related Impurities of Clonidine in Drug Substance and in Tablet Dosage Form5
In vivo and in vitro chemical composition and biological activity of traditional vs. dispensing granule decoctions of Coptidis Rhizoma: A comparative study5
Development and Validation of an LC–MS/MS Method for the Quantification of HY‐078020 in Human Plasma Using Liquid–Liquid Extraction and Its Application to Human Pharmacokinetic Study5
Revealing the mechanism of Gualou–Xiebai against myocardial ischemia based on network pharmacology and energy metabolism strategies5
Development, evaluation of critical method variables and stability assessment using a Box–Behnken design for the determination of organic impurities in a pharmaceutical dosage form of a centrally acti5
Spectrum‐Effect Relationship Between Fingerprints and Anti‐Inflammatory and Antitussive Activities of Raw and Processed Mume Fructus Extracts5
Unraveling the Material Basis of Compound Nanxing Zhitong Plaster: A Multimodal Study Combining Chemical Analysis, Network Pharmacology, and Transdermal Pharmacokinetics5
Determination of six core components from Mahuang Xuanfei Zhike syrup in rat plasma and tissues by UPLC–MS/MS: Application to a pharmacokinetics and tissue distribution study5
Jiedu Tongluo Tiaogan Formula Modulates Glycolipid Metabolism in Type 2 Diabetes via Pyroptosis: Network Pharmacology and In Vivo Analysis5
Correction to “A LC–MS/MS Method for the Simultaneous Determination of 6‐Cyanodopamine, 6‐Nitrodopamine, 6‐Nitrodopa, 6‐Nitroadrenaline and 6‐Bromodopamine in Human Plasma and Its Clinical Application5
In Silico Assessment and Quantitative Estimation of Potential Toxic Impurities From Propafenone (PFN) Through Generic Route and Using UPLC‐MS/MS Technique5
Investigation Into the Chemical Constituents and Cytotoxic Effects on Lung Cancer Cells of the Rhizomes of Polygonum bistorta L. and Polygonum paleaceum Wall.5
Metabolism of four novel structural analogs of ketamine, 2‐FXE [2‐(ethylamino)‐2‐(2‐fluorophenyl) cyclohexan‐1‐one], 2‐MDCK [2‐(methylamino)‐2‐(o‐tolyl) cyclohexan‐1‐one], 3‐DMXE [2‐(ethylamino5
Analysis of omarigliptin forced degradation products by ultra‐fast liquid chromatography, mass spectrometry, and in vitro toxicity assay5
An assessment of the antihyperlipidemic ingredients of Qi Ge Decoction based on metabolomics combined with serum pharmacochemistry5
Stable Isotope‐Resolved Metabolomics in Elucidating Mitochondrial Metabolic Reprogramming and Therapeutic Targets5
Research Progress on the Material Basis of Traditional Chinese Medicines Based on Chemical Biology Methods5
Chemical characterization, multivariate analysis and comparison of biological activities of different parts of Fraxinus mandshurica5
Highly sensitive liquid chromatography–mass spectrometry method for the quantitative analysis of mometasone furoate in human plasma: Method validation and application to clinical pharmacokinetic studi5
Protective effects of Typhonii Rhizoma in rheumatoid arthritis rats revealed by integrated metabolomics and network pharmacology5
Metabolomics study of the hepatoprotective effect of total flavonoids of Mallotus apelta leaf in carbon tetrachloride‐induced liver fibrosis in rats5
Superior In Vivo Efficacy of Fermented Over Aqueous Astragalus membranaceus in Diabetic Nephropathy: A Systematic Pharmacological Evaluation and Mechanis5
Elucidating the mechanisms underlying the anti‐hyperlipidemic effects of Laportea bulbifera using integrated serum metabolomics and network pharmacology5
Combining Online HPLC‐ABTS Screening With Machine Learning to Predict the Bioactivity of Antioxidant Components in Pandani Tectorii Radix et Rhizoma4
Comparison of the Antioxidant Capacity of Cell Wall‐Broken Decoction Pieces and Traditional Decoction Pieces of Astragli Radix Based on HPLC‐ABTS Analytical Method4
Evaluating the behavior and principle of deep eutectic solvent on ephedrine‐type alkaloid extraction from Ephedrae Herba4
Identification and Verification of the Anti‐Insomnia Compounds From Herbal Pair Albiziae Cortex and Polygoni Multiflori Caulis Using Immobilized 5‐HT 1A 4
Advances in mass spectrometry for metabolomics: Strategies, challenges, and innovations in disease biomarker discovery4
Validated HPLC‐UV Detection Method for Cefiderocol Quantification in a Critical Patient Receiving Fetcroja and Treated With Extracorporeal Replacement Therapies4
A comparative metabolomics study on dried and processed Rehmannia Radix4
Olanzapine‐induced weight gain and lipid dysfunction in mice between different gender4
Sorption and mobility assessment of tembotrione in soils of upper, trans and middle Gangetic plain zones of India4
Sample pretreatment and HPLC determination of antiplatelet drug ticagrelor in blood plasma from patients with acute coronary syndromes4
Development and Validation of an LC–MS/MS Assay for Quantitative Analysis of Nusinersen in Human CSF and Plasma4
Serum metabolic profile evidence for relationship between schizophrenia and depression: An untargeted metabolomics4
Absorption characteristics of ilexgenin A and ilexsaponin B1 in human umbilical vein endothelial cells after administration of the total triterpenoid saponins from Ilex pubescens4
A Simple and New HPLC Technique for the Determination of Monothioglycerol, an Antioxidant, in Raw Materials and Parenteral Preparations: Assessment of Greenness, Blueness, and Whiteness Scores4
Preclinical pharmacokinetics and metabolism study of SCO‐267, a GPR40 full agonist, in beagle dogs using ultra‐high performance liquid chromatography coupled to tandem mass spectrometry4
Integrated Characterization and Pharmacokinetics of Kanli Granule in Rats Based on UPLC‐Q‐TOF‐MS/MS: In Vitro and In Vivo Component Screening4
Establishing a multi‐method approach for unprecedented detection and quantification of 13 genotoxic impurities (GTIs) in Apixaban drug substance through ultra‐performance liquid chromatography (UPLC)4
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Identification and Multidimensional Evaluation of Quality Markers in Yupingfeng via UPLC‐Q‐Orbitrap‐MS, Network Pharmacology, UPLC‐UV Fingerprint, and UPLC‐QQQ‐MS4
A Simultaneous Determination of 14 Chemical Compounds From Rubi Fructus in Rat Plasma by UHPLC‐QTR4
Development and Validation of an RP‐HPLC Method for Organic Impurity Profiling in Baclofen Utilizing Robustness Through a Quality‐by‐Design (QbD) Approach: A Comprehensive Forced Degradation Assessmen4
A Rapid and Sensitive HPLC‐MS/MS Method for Quantification of Propranolol in Rat Plasma and the Application to Pharmacokinetic Study4
Gas chromatography mass spectrometer determination of dimethylamine impurity in N,N‐dimethylformamide solvent by derivatization of N,N‐dimethylbenzamide with benzoyl chlori4
Platycodon grandiflorum Attenuates Non‐Alcoholic Fatty Liver Disease in Rats Through Regulating Inflammatory Response via PPARγ and TLR4/NF‐κB Signaling Pathway4
Simultaneous determination of nirmatrelvir and ritonavir in human plasma using LC–MS/MS and its pharmacokinetic application in healthy Chinese volunteers4
Integrated UHPLC‐Q‐TOF‐MS Technology and Network Pharmacology Exploring the Pharmacodynamic Material Basis and Mechanism of Zhi‐Zi‐Hou‐Po Granule for Treatment of Depression–Anxiety Comorbidity4
Research progress in the application of proteomics technology in brain injury4
Differential metabolic profiles of ginsenosides in artificial gastric juice using ultra‐high‐pressure liquid chromatography coupled with linear ion trap‐Orbitrap mass spectrometry4
Analysis of blood concentrations and clinical application of risdiplam in patients with spinal muscular atrophy using ultra‐high performance liquid chromatography–tandem mass spectrometry4
Quantification of 3‐bromopyruvate in rat plasma by HPLC–MS/MS employing precolumn derivatization and the application to a pharmacokinetics study4
Optimizing Mirabegron Stability in Human Plasma: Method Development, Validation Through Integration of Esterase Inhibitors and Stabilizers4
Monitoring and method validation of organophosphorus/organochlorine pesticide residues in vegetables and fruits by gas chromatography4
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