Biomedical Chromatography

Article	Citations
Novel HPTLC densitometric methods for determination of tamsulosin HCl and tadalafil in their newly formulated dosage form: Comparative study and green profile assessment	42
A novel, rapid and simple UPLC–MS/MS method for quantification of favipiravir in human plasma: Application to a bioequivalence study	33
A Quality by Design and green LC technique for the determination of mast cell stabilizer and histamine receptor antagonist (Olopatadine HCl) in multiple formulations	29
Serum metabolomic profiling in patients with Alzheimer disease and amnestic mild cognitive impairment by GC/MS	27
Derivatization procedures and their analytical performances for HPLC determination in bioanalysis	24
An improved fabric‐phase sorptive extraction protocol for the determination of seven parabens in human urine by HPLC–DAD	23
Metabolomics and correlation network analysis of follicular fluid reveals associations between l‐tryptophan, l‐tyrosine and polycystic ovary syndrome	22
Accelerated stability study of the ester prodrug remdesivir: Recently FDA‐approved Covid‐19 antiviral using reversed‐phase‐HPLC with fluorimetric and diode array detection	21
Quality by design with design of experiments approach for development of a stability‐indicating LC method for enzalutamide and its impurities in soft gel dosage formulation	21
Determination of levofloxacin, ciprofloxacin, moxifloxacin and gemifloxacin in urine and plasma by HPLC–FLD–DAD using pentafluorophenyl core–shell column: Application to drug monitoring	21
Quality evaluation of rhubarb based on qualitative analysis of the HPLC fingerprint and UFLC–Q‐TOF–MS/MS combined with quantitative analysis of eight anthraquinone glycosides by QAMS	20
Recent applications of microextraction sample preparation techniques in biological samples analysis	20
Liquid chromatography–mass spectrometry applications for quantification of endogenous sex hormones	20
A simple and rapid HPLC method for determination of parabens and their degradation products in pharmaceutical dosage forms	19
Spectrum–effect relationship between GC‐QTOF‐MS fingerprint and antioxidant, anti‐inflammatory activities of Schizonepeta tenuifolia essential oil	17
Application of experimental design in HPLC method optimization and robustness for the simultaneous determination of canagliflozin, empagliflozin, linagliptin, and metformin in tablet	17
High‐performance thin‐layer chromatography based approach for bioassay and ATR–FTIR spectroscopy for the evaluation of antioxidant compounds from Asparagus racemosus Willd. aerial parts	17
A new HPLC–DAD method for contemporary quantification of 10 antibiotics for therapeutic drug monitoring of critically ill pediatric patients	17
Stability‐indicating reversed‐phase‐HPLC method development and validation for sacubitril/valsartan complex in the presence of impurities and degradation products: Robustness by quality‐by‐design appr	16
Assessment and application of Marfey’s reagent and analogs in enantioseparation: a decade’s perspective	16
The determination of β‐agonist residues in bovine tissues using liquid chromatography–tandem mass spectrometry	16
Simultaneous determination of nirmatrelvir and ritonavir in human plasma using LC–MS/MS and its pharmacokinetic application in healthy Chinese volunteers	16
Identifying potential serum biomarkers of breast cancer through targeted free fatty acid profiles screening based on a GC–MS platform	16
Impurity profiling and stability‐indicating method development and validation for the estimation of assay and degradation impurities of midostaurin in softgel capsules using HPLC and LC–MS	15
Chemical constituents of radix Actinidia chinensis planch by UPLC–QTOF–MS	15

Rhubarb anthraquinone glycosides protect against cerebral ischemia‐reperfusion injury in rats by regulating brain–gut neurotransmitters	14
A survey of polar stationary phases for hydrophilic interaction chromatography and recent progress in understanding retention and selectivity	14
Levels of residues and dietary risk assessment of the fungicides myclobutanil, penconazole, tebuconazole, and triadimenol in squash	14
Nanofluid of magnetic‐activated charcoal and hydrophobic deep eutectic solvent: Application in dispersive magnetic solid‐phase extraction for the determination and preconcentration of warfarin in biol	14
A gadolinium‐based magnetic ionic liquid for supramolecular dispersive liquid–liquid microextraction followed by HPLC/UV for the determination of favipiravir in human plasma	14
Identification of metabolic markers in patients with type 2 Diabetes by Ultrafast gas chromatography coupled to electronic nose. A pilot study	13
In vitro metabolism of 2′‐ribose unmodified and modified phosphorothioate oligonucleotide therapeutics using liquid chromatography mass spectrometry	13
A sensitive and high‐throughput quantitative liquid chromatography high‐resolution mass spectrometry method for therapeutic drug monitoring of 10 β‐lactam antibiotics, linezolid and two β	13
Method development for determination of imatinib and its major metabolite, N‐desmethyl imatinib, in biological and environmental samples by SA–SHS–LPME and HPLC	13
A simple isocratic LC method for quantification of trace‐level inorganic degradation impurities (ferricyanide, ferrocyanide, nitrite, and nitrate) in sodium nitroprusside injection and robustness by q	13
Development and validation of LC–MS method for the determination of heptaethylene glycol monomethyl ether in benzonatate bulk drugs	13
Development and validation of novel RP‐HPLC method for midostaurin determination using analytical quality by design approach from regulatory perspective and determination of major degradation compound	13
High‐throughput liquid chromatography/electrospray ionization–tandem mass spectrometry method using in‐source collision‐induced dissociation for simultaneous quantification of imatinib, dasatinib, bos	13
Degradation pathways and impurity profiling of the anticancer drug apalutamide by HPLC and LC–MS/MS and separation of impurities using Design of Experiments	13
Rapid simultaneous determination of gut microbial phenylalanine, tyrosine, and tryptophan metabolites in rat serum, urine, and faeces using LC–MS/MS and its application to a type 2 diabetes mellitus s	13
Phytochemical composition profile and space–time accumulation of secondary metabolites for Dracocephalum moldavica Linn. via UPLC–Q/TOF–MS and HPLC–DAD method	12
Determination of dopamine, noradrenaline, and adrenaline in Krebs–Henseleit solution by liquid chromatography coupled with tandem mass spectrometry and measurement of their basal release from Chelo	12
Determination of toosendanin and trans‐anethole in Fructus Meliae Toosendan and Fructus Foeniculi by HPLC–MS/MS and GC–MS/MS in rat plasma and their potential herb–herb interactions	12
Metabolite profiling of IMID‐2, a novel anticancer molecule of piperazine derivative: In silico prediction, in vitro and in vivo metabolite characterization using UPLC–QTOF–MS/MS	12
Validation of a simplified procedure for convenient and rapid quantification of reduced and oxidized glutathione in human plasma by liquid chromatography tandem mass spectrometry analysis	12
Quantification of eucalyptol (1,8‐cineole) in rat serum by gas chromatography–mass/mass spectrometry and its application to a rat pharmacokinetic study	12
Risk assessment, development and validation of a GC‐ECD‐based method for the quantification of cypermethrin from green pea	12
Comparison of chemical constituents of Bupleurum marginatum var. stenophyllum and Bupleurum chinense DC. using UHPLC–Q‐TOF–MS based on a metabonomics approach	12
Cutting‐edge LC–MS/MS applications in clinical mass spectrometry: Focusing on analysis of drugs and metabolites	12
Simultaneous determination of VD2, VD3, 25(OH) D2, and 25(OH) D3 in human plasma using electrospray LC–MS/MS as well as its application to evaluate VD plasma levels in depressive, schizophrenic patien	11
Simultaneous pharmacokinetic assessment of phytopharmaceuticals in fenugreek extract using LC–MS/MS in Sprague–Dawley rats	11
Validated HPLC‐MS/MS method for quantitation of AMG 510, a KRAS G12C inhibitor, in mouse plasma and its application to a pharmacokinetic study in mice	11
Dissipation and gas chromatographic method for the determination of profenofos residues in/on green pea and cucumber	11
Effect of CYP3A4 on liver injury induced by triptolide	11
A comparative analysis of raw and processed Radix Paeoniae Alba samples using HPLC, chemometrics, and antioxidant activity	11
Development and validation of liquid chromatography–tandem mass spectrometry method for the estimation of a potential genotoxic impurity 2‐(2‐chloroethoxy)ethanol in hydroxyzine	11
Quality by design‐based development and validation of an HPLC method for simultaneous estimation of pregabalin and piperine in dual drug‐loaded liposomes	11
A novel RP‐HPLC refractive index detector method development and validation for determination of trace‐level alcohols (un‐sulfated) in sodium lauryl sulfate raw material	11
Investigation of the therapeutic effect of Shaoyao Gancao decoction on CCL4‐induced liver injury in rats by metabolomic analysis	10
Determination of ceftazidime in plasma by RP‐HPLC and ultraviolet detection	10
Identifying the chemical markers in raw and wine‐processed Scutellaria baicalensis by ultra‐performance liquid chromatography/quadrupole time‐of‐flight mass spectrometry coupled with multiple s	10
Favipiravir (SARS‐CoV‐2) degradation impurities: Identification and route of degradation mechanism in the finished solid dosage form using LC/LC–MS method	10
Optimization of extraction process and the antioxidant activity spectrum–effect relationship of Angelica dahurica	10
Application of QbD based approach in development and validation of RP‐HPLC method for simultaneous estimation of methotrexate and baicalin in dual‐drug‐loaded liposomes	10
Identification of the absorptive constituents and their metabolites in vivo of Ziziphi Spinosae Semen by UPLC–ESI–Q‐TOF–MS/MS	10
Comparative pharmacokinetic and bioavailability study of lobetyolin in rats after administration of lobetyolin and Codonopsis pilosula extract by ultra‐performance LC–tandem mass spe	10
Enantioselective analysis of venlafaxine and its active metabolites: A review on the separation methodologies	10
A validated surrogate analyte UPLC–MS/MS assay for quantitation of TUDCA, TCDCA, UDCA and CDCA in rat plasma: Application in a pharmacokinetic study of cultured bear bile powder	10
Dimethyldioctadecylanimonium bentonite immobilized magnetic chitosan nanoparticles as an efficient adsorbent for vortex‐assisted magnetic dispersive micro‐solid‐phase extraction of celecoxib from huma	10
Nano‐LC: An updated review	10
Residue analysis and kinetics modeling of thiophanate‐methyl, carbendazim, tebuconazole and pyraclostrobin in apple tree bark using QuEChERS/HPLC–VWD	10
Development of an HPLC–MS method for the determination of four terpene trilactones in Ginkgo biloba leaf extract via quality by design	10
A novel method for investigating the mechanism of the anti‐rheumatoid arthritis activity of Angelicae pubescentis radix by integrating UHPLC–QTOF/MS and network pharmacology	10
Simultaneous determination of cellular adenosine nucleotides, malondialdehyde, and uric acid using HPLC	10
Rapid identification of chemical composition and metabolites of Pingxiao Capsulein vivousing molecular networking and untargeted data‐dependent tandem mass spectrometry	10

An efficient method for the determination of enantiomeric purity of racemic amino acids using micellar chromatography, a green approach	10
Stability‐indicating method development and validation for quantitative estimation of assay and organic impurities of antiviral drug baloxavir marboxil in drug substance and pharmaceutical dosage form	10
Systematic screening and characterization of absorbed constituents and in vivo metabolites in rats after oral administration of Rhizoma coptidis using UPLC‐Q‐TOF/MS	9
Stability‐indicating ultra performance liquid chromatography method development and validation for simultaneous estimation of metformin, linagliptin, and empagliflozin in bulk and pharmaceutical dosag	9
Development, method validation and simultaneous quantification of eleven bioactive natural products from high‐altitude medicinal plant by high‐performance liquid chromatography	9
Metabolomics analysis of multidrug resistance in colorectal cancer cell and multidrug resistance reversal effect of verapamil	9
A strategy for qualitative and quantitative profiling of Angelicae Pubescentis Radix and detection of its analgesic and anti‐inflammatory components by spectrum–effect relationship and multivariate st	9
Optimization of extraction and quantification technique for phenolics content of garlic (Allium sativum): An application for comparative phytochemical evaluation based on cultivar or	9
The separation sciences, the front end to proteomics: An historical perspective	9
Capillary electrophoresis and ultra‐high‐performance liquid chromatography methods in clinical monitoring of creatinine in human urine: A comparative study	9
Identification of cattle poisoning by Bifenthrin via earwax analysis by HS/GC–MS	9
Unique liquid chromatography technique for the determination of mirabegron in the presence of polymers; robustness by Design Expert in the light of Quality by Design	9
Development and validation of an HPLC–MS/MS method to simultaneously quantify alectinib, crizotinib, erlotinib, gefitinib and osimertinib in human plasma samples, using one assay run	9
Application of achiral–chiral two‐dimensional HPLC for separation of phenylalanine and tryptophan enantiomers in dietary supplement	9
Validated HPLC‐UV method for simultaneous quantification of phosphatidylinositol 3‐kinase inhibitors, copanlisib, duvelisib and idelalisib, in rat plasma: Application to a pharmacokinetic study in rat	9
Identification of prototypes from Ligustri Lucidi Fructus in rat plasma based on a data‐dependent acquisition and multicomponent pharmacokinetic study	9
Comparative analysis of chemical constituents by HPLC–ESI–MSn and antioxidant activities of Dendrobium huoshanense and Dendrobium officinale	9
Pharmacokinetic–pharmacodynamic modeling analysis and anti‐inflammatory effect of Wangbi capsule in the treatment of adjuvant‐induced arthritis	9
Development of a Pteris vittata L. compound database by widely targeted metabolomics profiling	9
Simultaneous determination of colchicine and febuxostat in rat plasma: Application in a rat pharmacokinetic study	9
Metabolomic characterization of semen from asthenozoospermic patients using ultra‐high‐performance liquid chromatography–tandem quadrupole time‐of‐flight mass spectrometry	8
Screening of hepatotoxic compounds in Psoralea corylifolia L., a traditional Chinese herbal and dietary supplement, using high‐resolution mass spectrometry and high‐content imaging	8
Mass spectrometry imaging technology in metabolomics: A systematic review	8
Simultaneous determination of six antibiotics in human serum by high‐performance liquid chromatography with UV detection	8
Stability‐indicating liquid chromatography method development for assay and impurity profiling of amitriptyline hydrochloride in tablet dosage form and forced degradation study	8
Chemical profiling and characterization of phenolic acids, flavonoids, terpene glycosides from Vangueria agrestis using ultra‐high‐performance liquid chromatography/ion mobility quadrupole time	8
Evaluation of green and efficient deep eutectic solvents as media for extracting alkaloids from lotus leaf	8
Hepatotoxicity and nephrotoxicity assessment on ethanol extract of Fructus Psoraleae in Sprague Dawley rats using a UPLC–Q‐TOF–MS analysis of serum metabolomics	8
Simultaneous quantitative determination of liraglutide and insulin degludec in rat plasma by liquid chromatography–tandem mass spectrometry method and its application	8
Enrichment of flavonoid‐rich extract from Bidens bipinnata L. by macroporous resin using response surface methodology, UHPLC–Q‐TOF MS/MS‐assisted characterization and comprehensive e	8
Evaluation of the effect of Dahuang–Mudan decoction on TNBS‐induced colitis using UPLC–QTOF/MS‐based metabolomic analysis	8
MS‐based metabolite analysis of two licorice chalcones in mice plasma, bile, feces, and urine after oral administration	8
Development of a simultaneous analytical method for clozapine and its metabolites in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry with linear range adjuste	8
A QbD‐led simple and sensitive RP‐UHPLC method for simultaneous determination of moxifloxacin, voriconazole, and pirfenidone: An application to pharmaceutical analysis	8
A novel UPLC–MS/MS method for simultaneous quantification of trigonelline, 4‐hydroxyisoleucine, and diosgenin from Trigonella foenum‐graecum extract: Application to pharmacokinetic s	8
Metabolic profiling of aromatic compounds in cerebrospinal fluid of neurosurgical patients using microextraction by packed sorbent and liquid–liquid extraction with gas chromatography–mass spectrometr	8
The related mechanism of complete Freund's adjuvant‐induced chronic inflammation pain based on metabolomics analysis	8
A review of chromatographic methods for bioactive tryptophan metabolites, kynurenine, kynurenic acid, quinolinic acid, and others, in biological fluids	8
Development and validation of a liquid chromatography–tandem mass spectrometry method for the simultaneous analysis of androgens, estrogens, glucocorticoids and progestagens in human serum	8
Simultaneous determination of skimmin, apiosylskimmin, 7‐hydroxycoumarin and 7‐hydroxycoumarin glucuronide in rat plasma by liquid chromatography–Orbitrap mass spectrometry and its application to phar	8
Rapid determination of rosmarinic acid and its two bioactive metabolites in the plasma of rats by LC–MS/MS and application to a pharmacokinetics study	8
Capillary electrophoresis‐based methodology for screening of oligonucleotide aptamers	8
Comparative pharmacokinetics study of six effective components between two dosage forms of Qixue–Shuangbu Prescription in rats by UPLC–MS/MS	8
Assessment of synthetic cannabinoid FUB‐AMB and its ester hydrolysis metabolite in human liver microsomes and human blood samples using UHPLC–MS/MS	8
Spleen and thymus metabolomics strategy to explore the immunoregulatory mechanism of total withanolides from the leaves of Datura metel L. on imiquimod‐induced psoriatic skin dermati	7
LC–MS‐based plasma metabolomics study of the intervention effect of different polar parts of hawthorn on gastrointestinal motility disorder rats	7
Determination of plasma homocysteine with a UHPLC–MS/MS method: Application to analyze the correlation between plasma homocysteine and whole blood 5‐methyltetrahydrofolate in healthy volunteers	7
Determination of diuretics in human urine using HPLC coupled with magnetic solid‐phase extraction based on a metal–organic framework	7
Determination of cannabinoids in plasma using salting‐out‐assisted liquid–liquid extraction followed by LC–MS/MS analysis	7
Deep eutectic solvent as the acceptor phase in three‐phase hollow fiber liquid‐phase microextraction for the determination of pyrethroid insecticides from environmental water samples prior to HPLC	7
Development and validation of an LC–MS/MS method for relevant drugs in epilepsy patients using dried blood spots	7
Pharmacokinetic studies of ginsenosides Rk1 and Rg5 in rats by UFLC–MS/MS	7
Automated sample preparation for the detection and confirmation of hypoxia‐inducible factor stabilizers in urine	7
Derivatization‐based quadruplex LC/ESI–MS/MS method for high throughput quantification of serum dehydroepiandrosterone sulfate	7
Simultaneous determination of serum homocysteine, cysteine, and methionine in patients with schizophrenia by liquid chromatography–tandem mass spectrometry	7
Nine absorbed components pharmacokinetic of raw and processed Moutan Cortex in normal and blood‐heat and hemorrhage syndrome model rats	7
Stability‐indicating liquid chromatography method development and validation for impurity profiling of montelukast sodium in bulk drug and tablet dosage form	7
Analysis of chemical variations between raw and wine‐processed Ligustri Lucidi Fructus by ultra‐high‐performance liquid chromatography–Q‐Exactive Orbitrap/MS combined with multivariate statistical ana	7
Intranasal administration of perillyl alcohol–loaded nanoemulsion and pharmacokinetic study of its metabolite perillic acid in plasma and brain of rats using ultra‐performance liquid chromatography/ta	7
Green analysis of newly approved binary omeprazole/aspirin mixture in presence of aspirin impurity using ultra‐high‐performance liquid chromatography and thin‐layer chromatography methods	7
Determination of amlodipine, indapamide and perindopril in human plasma by a novel LC–MS/MS method: Application to a bioequivalence study	7
LC–DAD/ESI–MS/MS characterization of phenolic constituents in Rosa canina L. and its protective effect in cells	7
LC–QTOF–MS‐based metabolite profiling and evaluation of α‐glucosidase inhibitory kinetics of Coccinia grandis fruit	7
Pharmacokinetic study of three different formulations of l‐tetrahydropalmatine in brain tissues of rats	7
Forced degradation studies of norepinephrine and epinephrine from dental anesthetics: Development of stability‐indicating HPLC method and in silico toxicity evaluation	7
Micellar liquid chromatographic green enantioseparation of racemic amino alcohols and determination of elution order	7
Metabolic infrastructure of pregnant women with methylenetetrahydrofolate reductase polymorphisms: A metabolomic analysis	7
What is necessary for next‐generation atmospheric environmental standards? Recent research trends for PM2.5‐bound polycyclic aromatic hydrocarbons and their derivatives	7
Simultaneous determination of gallic acid, methyl gallate, and 1,3,6‐tri‐O‐galloyl‐β‐d‐glucose from Turkish galls in rat plasma using liquid chromatography‐tandem mass	7
Analytical method development and determination of hydrocortisone acetate and fusidic acid simultaneously in cream formulation, by reversed‐phase HPLC	7
UPLC–ESI–Q‐TOF–MS/MS analysis of anticancer fractions from Ophiocordyceps xuefengensis and Ophiocordyceps sinensis	6
Metabolomics study of cerebrospinal fluid from diabetic rats with cognitive impairment simultaneously treated with Panax quinquefolius and Acorus gramineus	6
Retention behaviour of analytes in reversed‐phase high‐performance liquid chromatography—A review	6
Exploring the Q‐markers of Angelica sinensis (Oliv.) Diels of anti‐platelet aggregation activity based on spectrum–effect relationships	6
Development and validation of a cost‐effective and sensitive bioanalytical HPLC‐UV method for determination of lopinavir in rat and human plasma	6
Using a stable isotope‐labeled internal standard for liquid chromatography–tandem mass spectrometry quantitation of meloxicam in human plasma	6
Dried blood spots for doping controls—Development of a comprehensive initial testing procedure with fully automated sample preparation	6
Rapid determination of acyclovir, its main metabolite 9‐carboxymethoxymethylguanine, ganciclovir, and penciclovir in human serum using LC–MS/MS	6
A strategy to explore the quality markers of Ziziphi Spinosae semen by combining metabolic in vivo study with network pharmacology	6
A rapid HPLC–MS/MS method for determining busulfan in hemolytic samples from children with hematopoietic stem cell transplantation	6

Fluorimetric determination of the enantiomers of vigabatrin, an antiepileptic drug, by reversed‐phase HPLC with a novel diastereomer derivatization reagent	6
Rapid screening and evaluation of XOD inhibitors and O2•− scavenger from total flavonoids of Ginkgo biloba leaves by LC–MS and multimode microplate reader	6
Comparative investigation of raw and processed products of Gardeniae Fructus and Gardenia jasminoides var. radicans using HPLC coupled with chemometric methods	6
Simultaneous quantification of cyclosporin, tacrolimus, sirolimus and everolimus in whole blood by UHPLC–MS/MS for therapeutic drug monitoring	6
Sensitive, wide‐range and high‐throughput quantification of cyclosporine in whole blood using ultra‐performance liquid chromatography coupled to tandem mass spectrometry and comparison with an antibod	6
Accurate and simple determination of oxcarbazepine in human plasma and urine samples using switchable‐hydrophilicity solvent in GC–MS	6
Dissipation kinetics and dietary risk assessment of spiromesifen on major summer vegetables using good agricultural practices	6
An effective and stability‐indicating method development and optimization utilizing the Box–Behnken design for the simultaneous determination of acetaminophen, caffeine, and aspirin in tablet formulat	6
Application of QbD‐based approach to the development and validation of an RP‐HPLC method for simultaneous estimation of pregabalin and naringin in dual‐drug loaded liposomes	6
Systematic characterization of the chemical constituents in vitro and prototypes in vivo of Dingkun Dan using ultra‐high‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry c	6
Integrative metabolic profile of myelodysplastic syndrome based on UHPLC–MS	6
Electrophoretic deposition of polyaniline nanofibers on a stainless steel wire as an adsorbent for determination of tamoxifen by SPME/GC–FID in urine samples	6
A new method for detecting Na+, K+‐ATPase activity by ICP–MS: Quantitative analysis on the inhibitory effect of rhein on Na+, K+‐ATPase activity by ICP–MS i	6
A validated stability‐indicating reversed‐phase‐HPLC method for dipyridamole in the presence of degradation products and its process‐related impurities in pharmaceutical dosage forms	6
High‐throughput protein precipitation method with 96‐well plate for determination of doxepin and nordoxepin in human plasma using LC–MS/MS	6
Qualitative and quantitative analysis of phenolic acid glycosides in Ginkgo biloba L. leaf, G. biloba leaf extract and its injection	6
Detection of catecholamine metabolites in urine based on ultra‐high‐performance liquid chromatography–tandem mass spectrometry	6
Quantitative determination of canagliflozin in human plasma samples using a validated HPTLC method and its application to a pharmacokinetic study in rats	6
Quantification of field‐incurred residues of cyantraniliprole and IN‐J9Z38 in cabbage/soil using QuEChERS/HPLC‐PDA and dietary risk assessment	6
QbD‐based stability‐indicating liquid chromatography (RP‐HPLC) method for the determination of flurbiprofen in cataplasm	6
An LC–ESI–MS/MS assay for the therapeutic drug monitoring of 15 antiseizure medications in plasma of children with epilepsy	6
Stability‐indicating HPLC method development and validation for simultaneous estimation of metformin, dapagliflozin, and saxagliptin in bulk drug and pharmaceutical dosage form	6
Development and validation of LC–QTOF–MS/MS method for the identification and determination of low levels of a genotoxic impurity, 4,6‐dichloro‐5‐nitro‐2‐(propylthio)pyrimidine in ticagrelor API	6
Simultaneous determination of five bioactive components of XiaoJin Capsule in normal and mammary gland hyperplasia rat plasma using LC–MS/MS and its application to a pharmacokinetic study	5
Development and validation of HPLC method for simultaneous quantification of alpha‐tocopherol (free or encapsulated) and cholesterol in semen cryopreservation media	5
Pharmacokinetic and metabolic profiling studies of osmundacetone in rats by UPLC–MS/MS and UPLC–QE–Orbitrap–HRMS	5
US FDA–validated TLC method with four greenness assessment evaluations for simultaneous determination of prednisolone and esomeprazole in spiked human plasma	5
A UPLC–MS/MS method for determination of endogenous l‐carnitine and acetyl‐l‐carnitine in serum of patients with depression	5
A rapid LC–MS/MS method for simultaneous determination of berberine and irbesartan in rat plasma: Application to the drug–drug pharmacokinetic interaction study after oral administration in rats	5
Comprehensive insights into the formation of metabolites of the ghrelin mimetics capromorelin, macimorelin and tabimorelin as potential markers for doping control purposes	5
Polycyclic aromatic hydrocarbons residues and the carcinogenic risk assessment to pregnant women in Nantong, China using QuEChERS method and HPLC—A pilot case study	5
Simultaneous determination of pinoxaden, cloquintocet‐mexyl, clodinafop‐propargyl ester and its major metabolite in barley products and soil using QuEChERS modified with multi‐walled carbon nanotubes	5
Development and validation of an innovative UPLC method to quantify lacosamide, oxcarbazepine, and lamotrigine in the serum of children with epilepsy in China	5
Liquid chromatography‐high resolution mass spectrometric method for the quantification of monomethyl auristatin E (MMAE) and its preclinical pharmacokinetics	5
A volatolomic approach using cerumen as biofluid to diagnose bovine intoxication by Stryphnodendron rotundifolium	5
Development and validation of an LC–MS/MS method for the quantification of artificial sweeteners in human matrices	5
The metabolites and biotransformation pathways in vivo after oral administration of ocotillol, RT5, and PF11	5
Simultaneous analysis of drugs administered to lung‐transplanted patients using liquid chromatography–tandem mass spectrometry for therapeutic drug monitoring	5
Changes in the essential oil content and composition of Salvia limbata C.A. Mey at different growth stages and altitudes	5
Mechanisms exploration of terrestrosin D on pulmonary fibrosis based on plasma metabolomics and network pharmacology	5
Development of effervescence‐assisted switchable polarity solvent homogeneous liquid‐phase microextraction for the determination of permethrin and deltamethrin in water samples prior to gas chromatogr	5
A rapid and sensitive LC–MS/MS method for the determination of vanillic acid in rat plasma with application to pharmacokinetic study	5
Uncovering the anticancer mechanism of petroleum extracts of Farfarae Flos against Lewis lung cancer by metabolomics and network pharmacology analysis	5
Activated carbon/diatomite‐based magnetic nanocomposites for magnetic solid‐phase extraction of S‐phenylmercapturic acid from human urine	5
Reversed‐phase‐HPLC enantioseparation and control of enantiomeric purity of duloxetine using a new chiral reagent and recovery of enantiomers	5
Study on the material basis of Dahuang Zhechong pill of anti‐hepatoma effect by promoting vascular normalization	5
A rapid and sensitive bioanalytical LC–MS/MS method for the quantitation of a novel CDK5 inhibitor 20–223 (CP668863) in plasma: Application to in vitro metabolism and plasma protein‐binding stu	5
Development of a precise quantitative method for monitoring sirolimus in whole blood using LC/ESI–MS/MS	5
Anti‐neuraminidase activity of chemical constituents of Balanophora involucrata	5
Evaluation of alkylamines and stationary phases to improve LC–MS of oligonucleotides	5
Chemometric analysis of active compounds and antioxidant and α‐glucosidase inhibitory activities for the quality evaluation of licorice from different origins	5
Simultaneous quantitation of serum caffeine and its metabolites by ultra‐high‐performance liquid chromatography–tandem mass spectrometry for CYP1A2 activity prediction in premature infants	5
Stability‐indicating HPLC method development and validation of rivaroxaban impurities and identification of forced degradation products using LC–MS/MS	5
UHPLC/GC‐TOF‐MS metabolomics, MTT assay, and molecular docking studies reveal physostigmine as a new anticancer agent from the ethyl acetate and butanol fractions ofKigelia africana(	5
Pharmacokinetic and bioavailability study of kurarinone in dog plasma by UHPLC–MS/MS	5
Rapid and cost‐effective LC–MS/MS method for determination of hydroxycitric acid in plasma: Application in the determination of pharmacokinetics in commercial Garcinia preparations	5
Trace‐level analysis of polychlorinated biphenyls, organochlorine pesticides and polycyclic aromatic hydrocarbons in human plasma or serum by dispersive liquid–liquid microextraction and gas chromatog	5
Inside‐tube solid‐phase microextraction as an interlink between solid‐phase microextraction and needle device for n‐hexane evaluation in air and urine headspace	5
Identification of the metabolites of n‐butylidenephthalide in rat and human liver microsomes by liquid chromatography–high‐resolution mass spectrometry	5
Pharmacokinetic comparisons of six steroid saponins in rat plasma following oral administration of crude and stir‐fried Fructus Tribuli extracts by UHPLC–MS/MS	5
Greenness profile assessment of selective liquid chromatographic methods for determination of a quaternary antimigraine combination along with three of their related official impurities	5
Recent advances in the detection of drugs of abuse by dried blood spots	5
Validated LC–MS/MS method for quantitation of total and free mycophenolic acid concentration and its application to a pharmacokinetic study in pediatric renal transplant recipients	5
Proteomics and metabolomics analyses reveal the full spectrum of inflammatory and lipid metabolic abnormalities in dyslipidemia	5
Orbitrap‐MS‐based untargeted metabolomics study on the therapeutic effect of colchicine on myocardial infarction	5
Simultaneous determination of asarinin, β‐eudesmol, and wogonin in rats using ultraperformance liquid chromatography–tandem mass spectrometry and its application to pharmacokinetic studies following a	5
Characterization of molecularly imprinted polymers for the extraction of tobacco alkaloids and their metabolites in human urine	5
Plasma amino acid metabolomic pattern in heart failure patients with either preserved or reduced ejection fraction: The relation to established risk variables and prognosis	5
Polydimethylsiloxane/ionic liquid sponge used in headspace solid‐phase extraction coupled with GC–MS for rapid analysis of essential oil in lavender	5
LC–MS/MS method for determination of seneciphylline and its metabolite, seneciphylline N‐oxide in rat plasma, and its application to a rat pharmacokinetic study	5
Acoustic ejection mass spectrometry: Development, applications, and future perspective	5
Dose identification of triamcinolone acetonide for noninvasive pre‐corneal administration in the treatment of posterior uveitis using a rapid, sensitive HPLC method with photodiode‐array detector	5
Characteristic profiling of Aconiti Lateralis Radix for distinguishing it from compatible herbal pair using UPLC–Q‐TOF–MS coupled with chemometrics	5
A robust, accurate, sensitive LC–MS/MS method to measure indoxyl sulfate, validated for plasma and kidney cells	5
High‐throughput UPLC‐Q‐TOF‐MS/MS coupled with multivariable data processing approach for the rapid screening and characterization of chemical constituents and potential bioactive compounds from Danggu	5
In silico–in vitro estimation of lipophilicity and permeability association for succinimide derivatives using chromatographic anisotropic systems and parallel artificial membrane permeability a	5
Pharmacokinetics and tissue distribution study of 15 ingredients of Polygonum chinense Linn extract in rats by UHPLC–MS/MS	5
Development of a sensitive and rapid UHPLC–MS/MS method for simultaneous quantification of nine compounds in rat plasma and application in a comparative pharmacokinetic study after oral administration	5
Dissipation and residue determination of penicillin G and its two metabolites in citrus under field conditions by DSPE/UPLC–MS/MS	4
Enhancing effect of borneol on pharmacokinetics of ginsenoside Rb1, ginsenoside Rg1, and notoginsenoside R1 in healthy volunteers after oral administration of compound	4
Urinary phenylethylamine metabolites as potential markers for sports drug testing purposes	4
Metabolomics approach based on utra‐performance liquid chromatography coupled to mass spectrometry with chemometrics methods for high‐throughput analysis of metabolite biomarkers to explore the abnorm	4
Chemical‐activity‐based quality marker screening strategy for Viscum articulatum	4
Development and validation of gas chromatography with electron capture detection method using QuEChERS for pesticide residue determination in cucumber	4
Isolation and identification in human blood serum of the proteins possessing the ability to bind with 48 kDa form of unconventional myosin 1c and their possible diagnostic and prognostic value	4
Dissipation kinetics, risk assessment, and waiting period of spiromesifen on chili fruits using gas chromatography–electron capture detector	4
Comparative analysis of excretion of six major compounds of Polygonum orientale L. extract in urine, feces and bile under physiological and myocardial ischemia conditions in rats usi	4
Rapid profiling of cantharidin analogs in Mylabris phalerata Pallas by ultra‐performance liquid chromatography–quadrupole time‐of‐flight–tandem mass spectrometry	4
Dissipation pattern and dietary risk assessment of some commonly used insecticides on tomato (Solanum lycopersicum L.)	4
Identification of carbonylated proteins from monocytic cells under diabetes‐induced stress conditions	4
Rapid screening of α‐glucosidase inhibitors in Hypericum perforatum L. using bio‐affinity chromatography coupled with UPLC/MS	4
An observation study of urinary biomarker exploratory in Alzheimer's disease using high‐resolution mass spectrometry	4
A dried blood spot assay with HPLC–MS/MS for the determination of larotrectinib in mouse blood and its application to a pharmacokinetic study	4
Evaluation of the effects of notoginseng total saponins (NS), safflower total flavonoids (SF), and the combination of NS and SF (CNS) on the activities of cytochrome P450 enzymes using a cocktail meth	4
UPLC–MS/MS simultaneous determination of seven active ingredients of Yaobitong capsule in rat plasma and its integrated pharmacokinetic application	4