OOIR: Observatory of International Research

Papers

(The TQCC of Biomedical Chromatography is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
	38
A new method for detecting Na⁺, K⁺‐ATPase activity by ICP–MS: Quantitative analysis on the inhibitory effect of rhein on Na⁺, K⁺‐ATPase activity by ICP–MS i	32
Development of stability‐indicating method for separation and characterization of benidipine forced degradation products using LC–MS/MS	31
A novel UPLC–MS/MS method for simultaneous quantification of trigonelline, 4‐hydroxyisoleucine, and diosgenin from Trigonella foenum‐graecum extract: Application to pharmacokinetic s	30
An UHPLC–QTOF–MS‐based strategy for systematic profiling of chemical constituents and associated in vivo metabolites of a famous traditional Chinese medicine formula, Yinchenhao decoction	28
Detection and identification of imperatorin metabolites in rat, dog, monkey, and human liver microsomes by ultra‐high‐performance liquid chromatography combined with high‐resolution mass spectrometry	27
Development of simultaneous quantitative analytical method for metabolites of hexosamine biosynthesis pathway in lung cancer cells using ultra‐high‐performance liquid chromatography‐tandem mass spectr	27
Dissipation pattern and dietary risk assessment of some commonly used insecticides on tomato (Solanum lycopersicum L.)	27
Lipidomics reveals the serum profiles of pediatric allergic rhinitis and its severity	24
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Mango peel extracts and mangiferin chromatographic Fourier‐transform infrared correlation with antioxidant, antidiabetic, and advanced glycation end product inhibitory potentials using in silico model	23
Matrix effect in bioanalytical assay development using supercritical fluid chromatography‐mass spectrometry	20
Development of a simultaneous quantification method of imatinib and sunitinib and their main metabolites and its application in patients with gastrointestinal stromal tumor	19
The pharmacokinetics and tissue distribution of curcumin following inhalation administration in rats—A comparative analysis with oral and intravenous routes	18
Evaluation of various polysaccharide‐based stationary phases for enantioseparation of chloro‐containing derivatives in normal phase liquid chromatography	18
Characterization and Analytical Method Validation for Potential Impurities of a Merchantability Drug Substance Fluoxetine HCl	18
In vivo detection of the epimer metabolites of sweroside via ultra‐performance liquid chromatography time‐of‐flight mass spectrometry combined with DNPH derivatization	17
Preparation of 5‐hydroxymethylfurfural from Schisandra chinensis (Turcz.) Baill by high‐speed counter‐current chromatography: Comparison of conventional and consecutive separation	17
Issue Information	17
Development of an efficient stability‐indicating LC–MS/MS method for the analysis of selexipag and characterization of its degradation products	16
Pioneering Human Plasma Detection of Haloperidol With 5‐pg/mL Sensitivity via Refined Sample Preparation and Advanced LC–MS/MS	16
Residue levels and risk assessment of acetamiprid–pyridaben mixtures in cabbage under various open field conditions	16
Insight gained via ultra‐performance liquid chromatography tandem mass spectrometry‐based metabolomics: Protective effect of Artemisia argyi H.Lév. & Vaniot essential oil on lipopolysacchar	15
Issue Information	15
RP‐HPLC method development, validation and pharmacokinetic applicability in preclinical evaluation of rhein treated with novel diacerein eutectics	15

A new simple method for quantification of cilostazol and its active metabolite in human plasma by LC–MS/MS: Application to pharmacokinetics of cilostazol associated with CYP genotypes in health	15
Simultaneous determination of monocrotaline and its N‐oxide metabolite in rat plasma using LC–MS/MS: Application to a pharmacokinetic study	15
Chromatographic analysis and antioxidant potency of the crude extract of Xanthium spinosum in various fractions	14
Investigation of the therapeutic effect of Hedan tablets on high‐fat diet‐induced obesity in rats by GC–MS technology and 16S ribosomal RNA gene sequencing	14
Determination of three C18‐oxygenated steroids in adrenal lesion segments in primary aldosteronism by super‐selective adrenal venous sampling and LC/ESI–MS/MS	14
Characteristic profiling of Aconiti Lateralis Radix for distinguishing it from compatible herbal pair using UPLC–Q‐TOF–MS coupled with chemometrics	13
Issue Information	13
Comparative phytochemical study of methanolic and ethanolic extracts of Thymus linearis and their antibacterial and antioxidant potential	13
Evaluation of lipophilicity and drug‐likeness of donepezil‐like compounds using reversed‐phase thin‐layer chromatography	13
Pharmacokinetic and pharmacodynamic herb–drug interactions of common over‐the‐counter pain medications	13
Therapeutic potential of Shaoyao Gancao Decoction in mitigating anti‐tuberculosis drug‐induced liver injury through Nrf‐2/HO‐1/NF‐κB signaling	13
Online preconcentration and determination of five alkaloids in Yangxinshi tablet by large‐volume sample stacking and micelle to solvent stacking in cyclodextrin‐modified electrokinetic chromatography	12
Characterization and traceability of two generations of standard reference material for the measurement of vitamin K₁(phylloquinone) at endogenous concentrations in human plasma and serum	12
Issue Information	12
Development of a joint derivatization protocol for the unequivocal identification of the monosaccharide composition in four dendrobium polysaccharides and free monosaccharide by GC–MS	12
Development and validation of gas chromatography with electron capture detection method using QuEChERS for pesticide residue determination in cucumber	12
Development and validation of a stability‐indicating ultra‐high‐performance liquid chromatography method for the estimation of ibrutinib and trace‐level quantification of related substances using qual	12
Development and validation of novel RP‐HPLC method for midostaurin determination using analytical quality by design approach from regulatory perspective and determination of major degradation compound	11
Potential role of the methanolic extract for Olea europaea (stem and leaves) on sporulation of Eimeria papillata oocysts: In vitro study	11
Spectroscopic characterization and pharmacokinetic evaluation of amorphous solid dispersions of glibenclamide for bioavailability enhancement in Wistar rats	11
Review of HPLC–MS methods for the analysis of nicotine and its active metabolite cotinine in various biological matrices	11
Multimodal Metabolomics Analysis Reveals That Classic Decoction Mitigates Myocardial Ischemia‐Induced Damage by Modulating Energy and Branched‐Chain Amino Acid Metabolism	11
Delineation of prototypical degradation mechanism, characterization of unknown degradation impurities by liquid chromatography–quadrupole‐time‐of‐flight–tandem mass spectrometry and stability‐indicati	10
LC–MS/MS method for determination of kansuinine a in rat plasma and its application to a rat pharmacokinetic study	10
LC–MS/MS method for quick detection of vonoprazan fumarate in human plasma: Development, validation and its application to a bioequivalence study	10
A pharmacokinetics interaction study of antiplatelet agents aspirin and clopidogrel combined with dl‐3‐n‐butylphthalide in rats by liquid chromatography–tandem mass spectrometry	10
Serum and urine metabolomics based on UPLC–QTOF/MS reveal the effect and potential mechanism of “schisandra–evodia” herb pair in the treatment of Alzheimer's disease	10
Effect of concomitant oral administration of ethanol on the pharmacokinetics of nicardipine in rats	10
The impact of insecticides containing deltamethrin and cyfluthrin on the composition of surface compounds in the larvae, females and males of Tenebrio molitor	10
Screening for α‐glucosidase inhibitors from Selaginella uncinata based on the ligand fishing combined with ultra‐high‐performance liquid chromatography–quadrupole time‐of‐flight–tandem m	10
Simultaneous quantitation of urine aldosterone and tetrahydroaldosterone in healthy Chinese subjects using a validated LC–MS/MS method	10
Comparative analysis of the liver‐protective effects of raw and stir‐fried semen of Hovenia dulcis in rats via gas chromatography–mass spectrometry–based serum metabolomic profiling	10
Process Optimization of Stir‐Fried Inonotus hispidus Based on the Box–Behnken Design‐Response Surface Method and the Component Variations During the Stir‐Frying Process	10
A liquid chromatography–tandem mass spectrometry method development for the quantification of favipiravir drug and its related impurities in rat plasma and its application to pharmacokinetic studies	9
Favipiravir (SARS‐CoV‐2) degradation impurities: Identification and route of degradation mechanism in the finished solid dosage form using LC/LC–MS method	9
Spectrum–effect relationship between HPLC fingerprint and hypoglycemic of litchi leaves (Litchi chinensis Sonn) in vitro	9
Profiling of widely targeted metabolomics for the identification of chemical composition in epidermis, xylem and pith of Gleditsiae Spina	9
An LC–ESI–MS/MS assay for the therapeutic drug monitoring of 15 antiseizure medications in plasma of children with epilepsy	9
Hybrid solid‐phase extraction to overcome interference due to phospholipids for determination of neratinib in human plasma using UPLC–MS/MS	8
Metabolomic analysis of amino acids and organic acids in aging mouse eyes using gas chromatography–tandem mass spectrometry	8
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Pharmacokinetic and metabolism study of ginsenoside Rb2 in rat by liquid chromatography combined with electrospray ionization tandem mass spectrometry	8
Simultaneous determination of cellular adenosine nucleotides, malondialdehyde, and uric acid using HPLC	8
Si Miao San relieves hyperuricemia by regulating intestinal flora	8
Serum metabolome analysis reveals medicinal fungi Phellinus igniarius ameliorated type 2 diabetes mellitus indications in rats via modulation of amino acid and carbohydrate metabolism	8
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Investigating the in vivo effect of Tribulus terrestris extract in middle cerebral artery occlusion rats using LC–MS‐based metabolomics combined with molecular docking	8
Supported liquid extraction combined with liquid chromatography tandem mass spectrometry for the quantitative analysis of a TLR7 agonist imiquimod LFX453 in plasma at low picograms per milliliter: Met	8
Systematic analysis of chemical profiles of Sophorae tonkinensis Radix et Rhizoma in vitro and in vivo using UPLC‐Q‐TOF‐MS^E	8

Lipidomics reveals the dysregulated ceramide metabolism in oxidized low‐density lipoprotein‐induced macrophage‐derived foam cell	7
Supercritical fluid chromatography for milligram preparation of enantiomers	7
Farfarae Flos Mitigates Cigarette Smoking‐Induced Lung Inflammation by Regulating the Lysophosphatidylcholine Biosynthesis and Tryptophan Metabolism	7
UPLC Estimate of Sofosbuvir and Ledipasvir Utilizing Greenness Tool in Conjunction With an Analytical Quality by Design	7
LC‐HRMS‐based targeted metabolomics for high‐throughput and quantitative analysis of 21 growth inhibition‐related metabolites in Chinese hamster ovary cell fed‐batch cultures	7
Comparative Chromatographic Analysis of Amino Acids in the Seeds of Three Nigella L. Representatives	7
Human plasma ricinine quantification by LC–HRMS after micro‐solid‐phase elution	7
A Simple Rapid HPLC‐UV Method for Assessing C‐Terminal Arginine Content in Darbepoetin Alfa	7
Assessment of remdesivir and its nucleoside metabolite in beagle dogs and healthy humans by liquid chromatography coupled with triple quadrupole mass spectrometry	7
Pharmacokinetic and metabolic profiling studies of osmundacetone in rats by UPLC–MS/MS and UPLC–QE–Orbitrap–HRMS	7
Green method by National Environmental Methods Index and Eco‐Scale Assessment for evaluation of gatifloxacin‐based product by HPLC	7
Impact of introducing a new biological matrix into a validated bioanalytical method: Focus on matrix protein content	7
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The delivery of nanoparticles improves the pharmacokinetic properties of celecoxib to open a therapeutic window for oral administration of insoluble drugs	7
Orbitrap‐MS‐based untargeted metabolomics study on the therapeutic effect of colchicine on myocardial infarction	7
A selective, sensitive and fast LC–MS/MS method for cabotegravir quantification in rat plasma and pharmacokinetic investigations	7
Determination of 59 Psychotropic Drugs, Including Antipsychotics, Antidepressants, Antiepileptics, Anti‐Alcohol Abuse Drugs, Anti‐ADHD Drugs, and Their Metabolites in Urine Using LC–MS/MS for Medicati	7
Quantification of serum thyroid hormones using tandem mass spectrometry in patients with Down syndrome	7
An effective LC–MS method for the simultaneous determination of a potential anti‐rheumatoid arthritis drug, carboxyamidotriazole, and its major metabolite in rat plasma	7
Metabolic characteristics and pharmacokinetic differences of Qiwei Tongbi oral liquid in rheumatoid arthritis rats	7
In vitro wound healing properties, antioxidant activities, HPLC–ESI–MS/MS profile and phytoconstituents of the stem aqueous methanolic extract of Dracaena reflexa Lam	7
A novel method for purification of biologically active C‐terminal fragment of human recombinant anti‐mullerian hormone	7
Metabolite Identification of Huangqi Guizhi Wuwu Granules in Rat Urine and Feces Based on Ultra–High‐Performance Liquid Chromatography With Quadrupole Time‐of‐Flight Mass Spectrometry	6
Phytochemical profile and pharmacological potential of Withania somnifera whole plant extracts	6
Innovative UPLC technique for concurrent quantification of etofenamate and benzyl nicotinate in the presence of methylparaben and benzyl alcohol in their topical cream: Greens, white, and Six Sigma me	6
A simple, high‐throughput and validated LC–MS/MS method for the determination of azithromycin in human plasma and its application to a clinical pharmacokinetic study	6
Adipo‐specific chemerin knockout alters the metabolomic profile of adipose tissue under normal and high‐fat diet conditions: Application of an untargeted liquid chromatography–tandem mass spectrometry	6
Degradation pathways and impurity profiling of the anticancer drug apalutamide by HPLC and LC–MS/MS and separation of impurities using Design of Experiments	6
Residue levels, household processing evolution, and risk assessment of chlorothalonil, SDS‐3701, metalaxyl, and dimethomorph in Dendrobium officinale Kimura et Migo	6
Determination of the dissipative behaviour and final residue of sodium nitrophenol in jujube by liquid chromatography–tandem mass spectrometry	6
Dispersive liquid–liquid microextraction and Monte Carlo simulation of margin of safety for octocrylene, EHMC, 2ES, and homosalate in sunscreens	6
Network pharmacology study on fermented soybeans for the prevention of Alzheimer's disease in older individuals	6
A novel LC–MS/MS approach to [¹⁹F]‐alfatide and alfatide for application in preclinical pharmacokinetics	6
A fluorinated chitosan‐based QuEChERS method for simultaneous determination of 20 organophosphorus pesticide residues in ginseng using GC–MS/MS	6
Identifying of Anticoagulant Ingredients From Moutan Cortex Based on Spectrum‐Effect Relationship Analysis Combined With GRA, PLS, and SVM Algorithms	6
Quantitation of tazemetostat in human plasma using liquid chromatography–tandem mass spectrometry	6
The Continued Mismeasurement of Plasma Serotonin: A Systematic Review	6
Quantitation of plasma angiotensin II in healthy Chinese subjects by a validated liquid chromatography tandem mass spectrometry method	6
Elucidating the mechanisms underlying the anti‐hyperlipidemic effects of Laportea bulbifera using integrated serum metabolomics and network pharmacology	6
Method validation, dissipation and residue status of fluopicolide and fosetyl‐aluminium in citrus using a rapid extraction method coupled with ultra‐performance liquid chromatography–tandem mass spect	6
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Metabolomic analysis of the sera of patients with the long‐term inhalation of caffeine‐sodium benzoate using LC–MS	6
Simultaneous determination of 3‐n‐butylphthalide and its metabolite 10‐hydroxy‐butylphthalide in rat plasma using liquid chromatography–tandem mass spectrometry and application to a pharmacokin	6
Widely Targeted Metabolomics Reveals the Bioactive Metabolites and Antioxidant Activities of Chinese Yam (Dioscorea opposita Thunb.) Peel	6
Developing LC–MS/MS methods to quantify rivaroxabanin human plasma and urine: Application to therapeutic drug monitoring	6
Metabolomic comparison between natural Huaier and artificial cultured Huaier	6
HPLC–PDA identification and resolution of rufinamide forced degradation impurities: A congregated chemometric expedite optimization coupled with factorials and desirability	6
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Metabolomics study of the hepatoprotective effect of total flavonoids of Mallotus apelta leaf in carbon tetrachloride‐induced liver fibrosis in rats	6
A Simple and Sensitive LC‐MS/MS Method for the Determination of Mobocertinib and Its Metabolite Desmethyl‐Mobocertinib in Human Plasma and Its Application to Clinical Pharmacokinetic Study	6
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The JAK2^V617F mutation and childhood type1 diabetic nephropathy?	6
Study on the material basis of Zhujing pill in treating fundus lesions through component analysis and network pharmacology	6
LC–MS/MS determination of HY072808, a novel candidate for treating atopic dermatitis, and its active metabolite: Application to a first‐in‐human pharmacokinetic study	6
Metabolomics and serum pharmacochemistry revealed the preventive mechanism of Gushudan in kidney‐yang‐deficiency‐syndrome rats	6
Spectrum–effect relationship study between ultra‐high‐performance liquid chromatography fingerprints and anti‐hepatoma effect in vitro of Cnidii Fructus	5
Screening and characterization of cosmetic efficacy components of Terminalia chebula based on biological activity‐guided methodology	5
Bone and periosteum protein analysis via tandem mass tag quantitative proteomics in pediatric patients with osteomyelitis	5
Anti‐rheumatoid arthritis effects of Xanthii Fructus by affecting the PI3K‐AKT signaling pathway based on TMT‐labeled quantitative proteomics	5
In vivo and in vitro chemical composition and biological activity of traditional vs. dispensing granule decoctions of Coptidis Rhizoma: A comparative study	5
Metabolism of four novel structural analogs of ketamine, 2‐FXE [2‐(ethylamino)‐2‐(2‐fluorophenyl) cyclohexan‐1‐one], 2‐MDCK [2‐(methylamino)‐2‐(o‐tolyl) cyclohexan‐1‐one], 3‐DMXE [2‐(ethylamino	5
Highly sensitive liquid chromatography–mass spectrometry method for the quantitative analysis of mometasone furoate in human plasma: Method validation and application to clinical pharmacokinetic studi	5
Biosynthesized silver nanoparticle–coated electro‐membrane extraction of perchlorate in different seafood samples	5
Preparation of amentoflavone‐loaded DSPE‐PEG₂₀₀₀ micelles with improved bioavailability and in vitro antitumor efficacy	5
Chemical characterization, multivariate analysis and comparison of biological activities of different parts of Fraxinus mandshurica	5
Impurity profiling and stability‐indicating method development and validation for the estimation of assay and degradation impurities of midostaurin in softgel capsules using HPLC and LC–MS	5
Simultaneous quantification of icaritin and its novel 3‐methylcarbamate prodrug in rat plasma using HPLC–MS/MS and its application to pharmacokinetic study	5
A simple and sensitive liquid chromatography triple quadrupole mass spectrometry method for the determination of XL092 in monkey plasma and its application to pharmacokinetic study	5
Mechanisms exploration of terrestrosin D on pulmonary fibrosis based on plasma metabolomics and network pharmacology	5
Comparative analysis of bioactive constituents and pharmacological activities from different parts of Nauclea officinalis	5
Synthesis, characterization and control of eight process‐related and two genotoxic fingolimod impurities by a validated RP‐UPLC method	5
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Spectrum‐Effect Relationship Between Fingerprints and Anti‐Inflammatory and Antitussive Activities of Raw and Processed Mume Fructus Extracts	5
Integrated pharmacokinetics of Huangqi Jianzhong Tang in normal and chronic atrophic gastritis rats	5
Development and validation of a liquid chromatography coupled with tandem mass spectrometry method for determining total and unbound pamiparib in human plasma and brain tumors	5
Nano‐LC: An updated review	5
Research Progress on the Material Basis of Traditional Chinese Medicines Based on Chemical Biology Methods	5
Bioanalytical Tandem Mass Spectrometry Method for Precise Measurement of Tranexamic Acid in Human Plasma With Unveiling Methodological Advancement: Green Assessment With Advanced Metrics	5
Issue Information	5
Pharmacokinetics and bioequivalence studies of fluvoxamine maleate tablets in healthy Chinese subjects	5

Simultaneous Quantification of Filgotinib and Its Active Metabolite in Human Plasma Using Liquid Chromatography–Tandem Mass Spectrometry: Validation and Clinical Application	5
Pharmacokinetic study of five components of Fuzheng Huayu tablets in healthy human plasma	5
Rapid analysis of components in Qizhiweitong tablets and plasma after oral administration in rats by UPLC–Q‐TOF–MS/MS based on a self‐developed database	5
Determination of six core components from Mahuang Xuanfei Zhike syrup in rat plasma and tissues by UPLC–MS/MS: Application to a pharmacokinetics and tissue distribution study	5
Protective effects of Typhonii Rhizoma in rheumatoid arthritis rats revealed by integrated metabolomics and network pharmacology	5
Mechanism of Jinteng Qingbi granules in the treatment of rheumatoid arthritis using metabolomics analysis	5
Revealing the mechanism of Gualou–Xiebai against myocardial ischemia based on network pharmacology and energy metabolism strategies	5
Retention behaviour of analytes in reversed‐phase high‐performance liquid chromatography—A review	5
Comparative analysis of six aconitine‐type alkaloids in decocting extracts between the different processed Fuzi (Aconiti Lateralis Radix praeparata) and its pharmacokinetic behavior in rats by HPLC‐MS	5
A validated stability‐indicating reversed‐phase‐UPLC method for simultaneous estimation of promethazine hydrochloride, methylparaben, propylparaben and sodium benzoate assay of cough suppressant and a	5
A MS^ALL quantitative method for the determination of Poloxamer 188 in rat plasma by UHPLC–Q‐TOF/MS and its application to pharmacokinetic study	5
Identification of the metabolites of nimbolide in rat by liquid chromatography combined with quadrupole/orbitrap mass spectrometry	5
A robust, accurate, sensitive LC–MS/MS method to measure indoxyl sulfate, validated for plasma and kidney cells	5
Metabolic profiling of emodin drug‐induced liver injury and silybin treatment in rats using ultra‐performance liquid chromatography‐quadrupole‐time‐of‐flight‐mass spectrometry: A metabolomic and mecha	5
Analysis of omarigliptin forced degradation products by ultra‐fast liquid chromatography, mass spectrometry, and in vitro toxicity assay	5
Simultaneous determination and quality evaluation of 16 compounds in Ligustri Lucidi Fructus covering different regions and processed products using ultra‐high‐performance liquid chromatography‐mass s	5
An assessment of the antihyperlipidemic ingredients of Qi Ge Decoction based on metabolomics combined with serum pharmacochemistry	5
Noval Selective Ligand‐Extraction of Bioactive Components in Complex Natural Products Applying Immobilized Multi‐Target Magnetic Beads	5
High‐salt diet contributes to excess oxidative stress and abnormal metabolism in mouse ovaries	5
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Lipidomic‐based investigation into the therapeutic effects of polyene phosphatidylcholine and Babao Dan on rats with non‐alcoholic fatty liver disease	5
Investigation of the Potential Material Basis and Mechanism of Astragali Radix Against Adriamycin‐Induced Nephropathy Model Rat by ¹H NMR and MS‐Based Untargeted Metabolomics Analysis	5
LC–HRMS methods for the quantification of two artemisinin drugs and their metabolites in rat blood and plasma	5
Enantioselective determination of phenthoate enantiomers in plant‐origin matrices using reversed‐phase high‐performance liquid chromatography–tandem mass spectrometry	5
Assessment of metabolic stability and pharmacokinetics by LC–MS/MS and establishment of the safe dose of IMID‐2, a novel anticancer molecule under drug discovery	5
Issue Information	5
Metabolomics analysis reveals Oct4 overexpression drives metabolic reprogramming and enhanced glycolysis and pentose phosphate pathway in lung adenocarcinoma cells	5
Development, evaluation of critical method variables and stability assessment using a Box–Behnken design for the determination of organic impurities in a pharmaceutical dosage form of a centrally acti	5
Establishment and Application of Time‐Resolved Fluorescence Strip Method for Biotin Detection in Milk Powder	4
Combining network pharmacology with chromatographic fingerprinting and multicomponent quantitative analysis for the quality evaluation of Astragali Radix	4
Analysis of blood concentrations and clinical application of risdiplam in patients with spinal muscular atrophy using ultra‐high performance liquid chromatography–tandem mass spectrometry	4
The antitumor activity and pharmacokinetics research of PPD‐Arg (Tos) using ultra‐performance liquid chromatography‐quadrupole‐time‐of‐flight mass spectrometry	4
Therapeutic drug monitoring of free vancomycin concentration in practice: A new analytical technique based on the HFCF–UF sample separation method	4
Sample pretreatment and HPLC determination of antiplatelet drug ticagrelor in blood plasma from patients with acute coronary syndromes	4
A comparative metabolomics study on dried and processed Rehmannia Radix	4
Determination and tissue distribution comparisons of five xanthones after orally administering crude and processed gamboge	4
Stability‐indicating liquid chromatography method development for assay and impurity profiling of amitriptyline hydrochloride in tablet dosage form and forced degradation study	4
Simultaneous determination of four fungicide residues in figs using liquid chromatography tandem mass spectrometry	4
Olanzapine‐induced weight gain and lipid dysfunction in mice between different gender	4
Trace‐level determination of potential genotoxic impurities in quetiapine fumarate using LC–MS	4
Pharmacokinetics of IMM‐H012 in rats using ultra‐performance liquid chromatography‐tandem mass spectrometry	4
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Exploring Potential Targets and Pathways of Toxicity Attenuation Through Serum Pharmacochemistry and Network Pharmacology in the Processing of Aconiti Lateralis Radix Praeparata	4
Simultaneous determination of nirmatrelvir and ritonavir in human plasma using LC–MS/MS and its pharmacokinetic application in healthy Chinese volunteers	4
Determination by UHPLC‐QTOF‐HRMS of Phosphatidylethanol (PEth) in Dried Blood Spots: Method Validation and Practical Application of a Rising Alcohol Abuse Biomarker With Minimally Invasive Sampling	4
Evaluation of green and efficient deep eutectic solvents as media for extracting alkaloids from lotus leaf	4
Effects of voriconazole and fluconazole on the pharmacokinetics of almonertinib in rats by UPLC–MS/MS	4
A novel standard‐free detection of adulteration method for sildenafil derivatives in dietary supplements	4
Optimization, extraction, and purification of three bioactive compounds from Entada phaseoloides by high‐speed countercurrent chromatography	4
A RP‐HPLC–DAD method for analysis of Brazilian southeast brown propolis and its leishmanicidal properties	4
Differential metabolic profiles of ginsenosides in artificial gastric juice using ultra‐high‐pressure liquid chromatography coupled with linear ion trap‐Orbitrap mass spectrometry	4
Oral solid dosage form using alternate crystalline neratinib maleate anhydrous form: Pharmaceutical, bioequivalent, and clinical perspectives	4
A green approach for the analysis of emtricitabine bictegravir and tenofovir in a pharmaceutical preparation using novel HPLC and spectrophotometric methods	4
Multimodal integrated strategy for the discovery and identification of antiplatelet aggregation Q‐markers in Paris polyphylla var. yunnanensis	4
Research progress in the application of proteomics technology in brain injury	4
Development and validation of an HPLC coupled with tandem mass spectrometry method for the determination of HSK7653, a novel super long‐acting dipeptidyl peptidase‐4 inhibitor, in human plasma and uri	4
Preclinical pharmacokinetics and metabolism study of SCO‐267, a GPR40 full agonist, in beagle dogs using ultra‐high performance liquid chromatography coupled to tandem mass spectrometry	4
Pharmacokinetics and tissue distribution of cantharidin after oral administration of aqueous extracts from Mylabris in rats	4
Serum metabolic profile evidence for relationship between schizophrenia and depression: An untargeted metabolomics	4
Development and validation of an HPLC–MS/MS method to simultaneously quantify alectinib, crizotinib, erlotinib, gefitinib and osimertinib in human plasma samples, using one assay run	4
Stability‐Indicating RP‐HPLC Method Development and Validation for Determination of Impurities in Loperamide Hydrochloride Capsules Dosage Form	4
Absorption characteristics of ilexgenin A and ilexsaponin B1 in human umbilical vein endothelial cells after administration of the total triterpenoid saponins from Ilex pubescens	4
Preparation, characterization, and pharmacokinetics of oridonin‐loaded liposomes	4
Evaluating the behavior and principle of deep eutectic solvent on ephedrine‐type alkaloid extraction from Ephedrae Herba	4
Application of QbD based approach in development and validation of RP‐HPLC method for simultaneous estimation of methotrexate and baicalin in dual‐drug‐loaded liposomes	4
A validated stability‐indicating reversed‐phase‐HPLC method for dipyridamole in the presence of degradation products and its process‐related impurities in pharmaceutical dosage forms	4
Recent advances in the chromatographic determination of the most commonly used anti‐hepatitis C drug sofosbuvir and its co‐administered drugs in human plasma	4
Monitoring and method validation of organophosphorus/organochlorine pesticide residues in vegetables and fruits by gas chromatography	4
Quantification of 3‐bromopyruvate in rat plasma by HPLC–MS/MS employing precolumn derivatization and the application to a pharmacokinetics study	4
Sorption and mobility assessment of tembotrione in soils of upper, trans and middle Gangetic plain zones of India	4
Determination of fingerprints contents of different extracts and parts of six endemic Salvia taxa by GC–MS: Source species for valuable compounds with drug or drug potential	4
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A metabolism‐based study of the mechanism of action of Scrophularia ningpoensis Hemsl. on nephrogenic edema	4
Issue Information	4
A new method providing complementary explanation of the blood‐enriching function and mechanism of unprocessed Angelica sinensis and its four kinds of processed products based on tissue‐integrat	4
An untargeted serum and urine lipidomics research based on UPLC–MS revealed the lipid alterations on adjuvant‐induced arthritis rats	4
Fluorescent immunochromatography of vancomycin in plasma: A rapid and sensitive quantitative analysis	4
Comparison of the Antioxidant Capacity of Cell Wall‐Broken Decoction Pieces and Traditional Decoction Pieces of Astragli Radix Based on HPLC‐ABTS Analytical Method	4
Metabolism, pharmacokinetics, and bioavailability of yuanhuacine in rat using LC–MS	4
Urinary excretion of silibinin diastereoisomers and their conjugated metabolites in rat and human at different dosages	4
Gas chromatography mass spectrometer determination of dimethylamine impurity in N,N‐dimethylformamide solvent by derivatization of N,N‐dimethylbenzamide with benzoyl chlori	4
Jiedu Tongluo Tiaogan Formula Modulates Glycolipid Metabolism in Type 2 Diabetes via Pyroptosis: Network Pharmacology and In Vivo Analysis	4
Investigation of the apoptosis‐inducing effect of docetaxel by comprehensive LC–MS–based metabolomics and network pharmacology approaches	4
HPLC and GC–MS–based metabolic profiles and in vivo anticonvulsant, sedative, and antinociceptive potentials of truffles Tirmania nivea and Tirmania pinoyi hydromethanolic extracts in mi	4
A metabolomics study on the mechanisms of Gardeniae fructus against α‐naphthylisothiocyanate‐induced cholestatic liver injury	4
Study on the antidepressive effects and mechanism of raw and fried Ziziphi Spinosae Semen via metabolomics and gut microbiota analysis	3
Simultaneous determination of eight analytes of Fuzheng Huayu recipe in beagle dog plasma by UHPLC–Q/exactive Orbitrap HRMS and its application to toxicokinetics	3
A validated LC–MS/MS method for simultaneous quantification of simvastatin and simvastatin acid in beagle plasma: Application to an absolute bioavailability study	3
Prediction and analysis of quality markers for Chuantieling gel patches based on HPLC fingerprinting and network pharmacology	3
Quantitation of levetiracetam concentrations in plasma and saliva samples by ultra‐performance liquid chromatography–tandem mass spectrometry: Application to therapeutic drug monitoring for pregnant w	3
Issue Information	3
A reversed‐phase‐high performance liquid chromatography method for simultaneous determination of paracetamol, caffeine, drotaverine HCl and their related impurities with dissolution profiling of their	3
Analysis of 10 urinary BTEX metabolites using LC–MS/MS	3
Exploring the potential of dried plasma collection cards for liquid chromatography coupled with tandem mass spectrometry quantitation of giredestrant in human plasma	3
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