Biomedical Chromatography

Article	Citations
Development of a simultaneous quantification method of imatinib and sunitinib and their main metabolites and its application in patients with gastrointestinal stromal tumor	42
Identification of Dendrobium devonianum Samples With Different Growth Years Based on Active Ingredients and Deduction of the Chemical Structural Transformation	38
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Development of simultaneous quantitative analytical method for metabolites of hexosamine biosynthesis pathway in lung cancer cells using ultra‐high‐performance liquid chromatography‐tandem mass spectr	24
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In vivo detection of the epimer metabolites of sweroside via ultra‐performance liquid chromatography time‐of‐flight mass spectrometry combined with DNPH derivatization	22
Preparation of 5‐hydroxymethylfurfural from Schisandra chinensis (Turcz.) Baill by high‐speed counter‐current chromatography: Comparison of conventional and consecutive separation	22
Characterization and Analytical Method Validation for Potential Impurities of a Merchantability Drug Substance Fluoxetine HCl	22
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The Isolation and Separation of Hydrophobic Bioactive Peptide Obtained From Tilapia ( Oreochromis niloticus	21
Development of stability‐indicating method for separation and characterization of benidipine forced degradation products using LC–MS/MS	20
Evaluation of various polysaccharide‐based stationary phases for enantioseparation of chloro‐containing derivatives in normal phase liquid chromatography	20
Simultaneous Determination of Four Active Ingredients in Snow Chrysanthemum by HPLC With Determination of Its Antioxidant Activity in Vitro	20
A Validated UPLC‐MS/MS Method for Monitoring Temozolomide and Perillyl Alcohol Metabolites in Biological Matrices: Insights From a Preclinical Pharmacokinetic Study	20
Integrative LC–MS/MS, Bioinformatics, and Molecular Dynamics Reveal Multitarget Antioxidant Mechanisms of Bushen Huoxue Decoction in Intervertebral Disc Degeneration	20
An UHPLC–QTOF–MS‐based strategy for systematic profiling of chemical constituents and associated in vivo metabolites of a famous traditional Chinese medicine formula, Yinchenhao decoction	19
An LC–MS/MS Method for the Quantitation of Metabolites M9, M12, and M20 of Bexicaserin in Human Cerebrospinal Fluid	17
Mango peel extracts and mangiferin chromatographic Fourier‐transform infrared correlation with antioxidant, antidiabetic, and advanced glycation end product inhibitory potentials using in silico model	17
Separation and Identification of Impurity of Chlortetracycline Hydrochloride Not Included in the European Pharmacopoeia	16
Lipidomics reveals the serum profiles of pediatric allergic rhinitis and its severity	16
Green Ultra‐Fast UPLC–MS/MS Method for Enasidenib Quantification in HLMs Matrix With the Metabolic Stability Assessment: In Silico Study for Structural Alerts, ADME Characteristics and Metaboslic Labi	15
Interference Assessment for High‐Performance Liquid Chromatography HbA1c Assays	15
Detection and identification of imperatorin metabolites in rat, dog, monkey, and human liver microsomes by ultra‐high‐performance liquid chromatography combined with high‐resolution mass spectrometry	15
Assessment of Apalutamide Metabolic Stability in HLMs Matrix Using a Sensitive and Fast UPLC‐MS/MS Method: In Silico Screening for Toxicity Alerts and Metabolic Lability	15

Residue levels and risk assessment of acetamiprid–pyridaben mixtures in cabbage under various open field conditions	14
Pioneering Human Plasma Detection of Haloperidol With 5‐pg/mL Sensitivity via Refined Sample Preparation and Advanced LC–MS/MS	14
Pharmacokinetic and pharmacodynamic herb–drug interactions of common over‐the‐counter pain medications	14
The pharmacokinetics and tissue distribution of curcumin following inhalation administration in rats—A comparative analysis with oral and intravenous routes	14
Matrix effect in bioanalytical assay development using supercritical fluid chromatography‐mass spectrometry	14
A Robust LC‐MS/MS Bioanalytical Strategy for Simultaneous Quantification of Tramadol HCl and Dexketoprofen Trometamol and Its Use in Pharmacokinetic Studies	14
Delineation of prototypical degradation mechanism, characterization of unknown degradation impurities by liquid chromatography–quadrupole‐time‐of‐flight–tandem mass spectrometry and stability‐indicati	13
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Therapeutic potential of Shaoyao Gancao Decoction in mitigating anti‐tuberculosis drug‐induced liver injury through Nrf‐2/HO‐1/NF‐κB signaling	13
Comparative phytochemical study of methanolic and ethanolic extracts of Thymus linearis and their antibacterial and antioxidant potential	13
Screening of Antiaging Active Components of Morinda officinalis and the Mechanism of Enhanced Efficacy After Salt‐Steaming	13
Online preconcentration and determination of five alkaloids in Yangxinshi tablet by large‐volume sample stacking and micelle to solvent stacking in cyclodextrin‐modified electrokinetic chromatography	13
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Potential role of the methanolic extract for Olea europaea (stem and leaves) on sporulation of Eimeria papillata oocysts: In vitro study	12
Metabolic Profiling of 5‐Methoxypinocembroside and Pharmacokinetics Study of Its Major Metabolite Alpinetin in Rat Plasma by UHPLC–MS	12
Determination of three C18‐oxygenated steroids in adrenal lesion segments in primary aldosteronism by super‐selective adrenal venous sampling and LC/ESI–MS/MS	12
Multimodal Metabolomics Analysis Reveals That Classic Decoction Mitigates Myocardial Ischemia‐Induced Damage by Modulating Energy and Branched‐Chain Amino Acid Metabolism	11
Investigation of the therapeutic effect of Hedan tablets on high‐fat diet‐induced obesity in rats by GC–MS technology and 16S ribosomal RNA gene sequencing	11
Metabolomics Reveals the Mechanism of American Ginseng in Alleviating Insulin Resistance by Reversing Metabolic Disorders in HepG2 Cells	11
RP‐HPLC method development, validation and pharmacokinetic applicability in preclinical evaluation of rhein treated with novel diacerein eutectics	11
Development and validation of novel RP‐HPLC method for midostaurin determination using analytical quality by design approach from regulatory perspective and determination of major degradation compound	11
Study on Quality Markers for Hypoglycemic Effects of Moringa oleifera Leaves by the Integration of	11
Insight gained via ultra‐performance liquid chromatography tandem mass spectrometry‐based metabolomics: Protective effect of Artemisia argyi H.Lév. & Vaniot essential oil on lipopolysacchar	11
Spectroscopic characterization and pharmacokinetic evaluation of amorphous solid dispersions of glibenclamide for bioavailability enhancement in Wistar rats	11
Chromatographic analysis and antioxidant potency of the crude extract of Xanthium spinosum in various fractions	11
Screening for α‐glucosidase inhibitors from Selaginella uncinata based on the ligand fishing combined with ultra‐high‐performance liquid chromatography–quadrupole time‐of‐flight–tandem m	11
Evaluation of lipophilicity and drug‐likeness of donepezil‐like compounds using reversed‐phase thin‐layer chromatography	11
The Effect of Kaempferol on Valsartan Metabolism In Vitro and In Vivo and the Underlying Mechanism With Cytochrome p450 Using UPLC‐MS/MS	10
Development and validation of a stability‐indicating ultra‐high‐performance liquid chromatography method for the estimation of ibrutinib and trace‐level quantification of related substances using qual	10
Application of Proteomics in the Study of Toxicology and Toxic Markers of Traditional Chinese Medicines	10
Simultaneous quantitation of urine aldosterone and tetrahydroaldosterone in healthy Chinese subjects using a validated LC–MS/MS method	10
A Comprehensive Review of Analytical Techniques for Doxycycline and Its Metabolites	10
Development and validation of gas chromatography with electron capture detection method using QuEChERS for pesticide residue determination in cucumber	10
Integrated Experimental and Computational Evaluation of the Gut‐Targeted Anticoccidial Potential of Agaricus bisporus Methanolic Extract	10
Farfarae Flos Mitigates Cigarette Smoking‐Induced Lung Inflammation by Regulating the Lysophosphatidylcholine Biosynthesis and Tryptophan Metabolism	10
Development of a joint derivatization protocol for the unequivocal identification of the monosaccharide composition in four dendrobium polysaccharides and free monosaccharide by GC–MS	10
Development and Validation of a UPLC‐MS/MS Method for the Determination of Apalutamide in Human Plasma and Its Application in a Bioequivalence Study	10
Spectrum–effect relationship between HPLC fingerprint and hypoglycemic of litchi leaves (Litchi chinensis Sonn) in vitro	10
Quality Difference Analysis of Pomegranate Peels Based on Multidimensional Fingerprint With Chemical Pattern Recognition	9
Comparative analysis of the liver‐protective effects of raw and stir‐fried semen of Hovenia dulcis in rats via gas chromatography–mass spectrometry–based serum metabolomic profiling	9
Hybrid solid‐phase extraction to overcome interference due to phospholipids for determination of neratinib in human plasma using UPLC–MS/MS	9
Optimization of Environmentally Sustainable UPLC‐PDA Method Using Box–Behnken for Simultaneous Quantifying Curcumin and Candesartan Cilexetil in On‐Demand Formulation for Treatment of Brain Ischemic I	9
Supported liquid extraction combined with liquid chromatography tandem mass spectrometry for the quantitative analysis of a TLR7 agonist imiquimod LFX453 in plasma at low picograms per milliliter: Met	9
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Amelioration of Guishao Yigong Decoction on Colorectal Cancer Through the Integration of 16S rRNA Sequencing and Fecal Metabolomics	9
Chromatography in Preparative/Industrial Scale Separation of Enantiomeric Mixtures	9
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Dissipation and Risk Assessment of a Combination Product of Chlorantraniliprole + Abamectin and Spirotetramat in Pomegranate Fruit and Juice	9
Determination of Schaftoside and Isoschaftoside in Rat Plasma Utilizing UPLC‐MS/MS	9
Beyond the Database: Integration of Network Pharmacology and UHPLC‐QTOF‐MS/MS to Reveal the Neuroprotective Potential of Bai Mi Decoction in Stroke Therapy	8

A pharmacokinetics interaction study of antiplatelet agents aspirin and clopidogrel combined with dl‐3‐n‐butylphthalide in rats by liquid chromatography–tandem mass spectrometry	8
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Simultaneous Determination of Buspirone, Alprazolam, Clonazepam, Diazepam, and Lorazepam by LC‐MS/MS: Evaluation of Greenness Using AGREE Tool	8
Dissipation Kinetics, Risk Assessment, and Decontamination Studies of Pyridalyl in Cabbage by GC–MS/MS	8
Sustainable RP‐HPLC Method Development Using AQbD Approach for Simultaneous Estimation of Valganciclovir Hydrochloride and Piperine‐Loaded Lipid Nanoparticles	8
Metabolite Identification of Huangqi Guizhi Wuwu Granules in Rat Urine and Feces Based on Ultra–High‐Performance Liquid Chromatography With Quadrupole Time‐of‐Flight Mass Spectrometry	8
Process Optimization of Stir‐Fried Inonotus hispidus Based on the Box–Behnken Design‐Response Surface Method and the Component Variations During the Stir‐Frying Process	8
LC–MS/MS method for quick detection of vonoprazan fumarate in human plasma: Development, validation and its application to a bioequivalence study	8
Rapid Analysis of Chemical Constituents in Blachia pentzii Leaves and Predictive Analysis of the Pharmacological Effects for Treatment of Rheumatoid Arth	8
Bioanalytical UHPLC–MS/MS Method for Quantification of Terbinafine in Ungual Delivery Studies	8
Assessment of remdesivir and its nucleoside metabolite in beagle dogs and healthy humans by liquid chromatography coupled with triple quadrupole mass spectrometry	8
Effect of concomitant oral administration of ethanol on the pharmacokinetics of nicardipine in rats	8
A liquid chromatography–tandem mass spectrometry method development for the quantification of favipiravir drug and its related impurities in rat plasma and its application to pharmacokinetic studies	8
Determination of 59 Psychotropic Drugs, Including Antipsychotics, Antidepressants, Antiepileptics, Anti‐Alcohol Abuse Drugs, Anti‐ADHD Drugs, and Their Metabolites in Urine Using LC–MS/MS for Medicati	8
Si Miao San relieves hyperuricemia by regulating intestinal flora	8
The Complex Formation Between Ginsenosides and Glutathione Utilized in Cosmetics to Promote Transdermal Absorption and Mask the Bad Odor of Glutathione	8
Serum and urine metabolomics based on UPLC–QTOF/MS reveal the effect and potential mechanism of “schisandra–evodia” herb pair in the treatment of Alzheimer's disease	8
Serum metabolome analysis reveals medicinal fungi Phellinus igniarius ameliorated type 2 diabetes mellitus indications in rats via modulation of amino acid and carbohydrate metabolism	8
Lateal Flow Immunoassay for Sensitive and Rapid Detection of Methylisomiroestrol in Pueraria candollei Using Monoclonal Antibody	8
A Simple Rapid HPLC‐UV Method for Assessing C‐Terminal Arginine Content in Darbepoetin Alfa	8
An LC–ESI–MS/MS assay for the therapeutic drug monitoring of 15 antiseizure medications in plasma of children with epilepsy	8
Investigating the in vivo effect of Tribulus terrestris extract in middle cerebral artery occlusion rats using LC–MS‐based metabolomics combined with molecular docking	8
Impact of introducing a new biological matrix into a validated bioanalytical method: Focus on matrix protein content	8
Supercritical fluid chromatography for milligram preparation of enantiomers	8
The delivery of nanoparticles improves the pharmacokinetic properties of celecoxib to open a therapeutic window for oral administration of insoluble drugs	7
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Development and Validation of a Rapid and Simple UHPLC–MS/MS Method for the Determination of Colchicine in Human Plasma	7
LC–MS/MS Assay for Simultaneous Quantification of Dual‐Targeting 1,5‐Diaryl‐1,2,4‐Triazole Sulfonamides (WA11–13) in Human Plasma	7
The Continued Mismeasurement of Plasma Serotonin: A Systematic Review	7
Innovative UPLC technique for concurrent quantification of etofenamate and benzyl nicotinate in the presence of methylparaben and benzyl alcohol in their topical cream: Greens, white, and Six Sigma me	7
Metabolomics and serum pharmacochemistry revealed the preventive mechanism of Gushudan in kidney‐yang‐deficiency‐syndrome rats	7
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Comparative Chromatographic Analysis of Amino Acids in the Seeds of Three Nigella L. Representatives	7
Identifying of Anticoagulant Ingredients From Moutan Cortex Based on Spectrum‐Effect Relationship Analysis Combined With GRA, PLS, and SVM Algorithms	7
An effective LC–MS method for the simultaneous determination of a potential anti‐rheumatoid arthritis drug, carboxyamidotriazole, and its major metabolite in rat plasma	7
Quantitation of tazemetostat in human plasma using liquid chromatography–tandem mass spectrometry	7
UPLC Estimate of Sofosbuvir and Ledipasvir Utilizing Greenness Tool in Conjunction With an Analytical Quality by Design	7
Phytochemical profile and pharmacological potential of Withania somnifera whole plant extracts	7
Human plasma ricinine quantification by LC–HRMS after micro‐solid‐phase elution	7
Metabolism of the Total Flavonoid Extract of Lithocarpus litseifolius (Hance) Chun in Rats	7
Network pharmacology study on fermented soybeans for the prevention of Alzheimer's disease in older individuals	7
Quantitative Determination and Stability of Trace Levels of Oxytocin in Human and Rhesus Macaque Urine by LC–MS/MS	7
Metabolic Profile In Vivo and Potential Mechanisms of Danggui Jianzhong Decoction Against Gastric Ulcer by Ultra‐High‐Performance Quadrupole Time‐of‐Flight Mass Spectrometry Combined With Network Phar	7
Degradation pathways and impurity profiling of the anticancer drug apalutamide by HPLC and LC–MS/MS and separation of impurities using Design of Experiments	6
A validated stability‐indicating reversed‐phase‐UPLC method for simultaneous estimation of promethazine hydrochloride, methylparaben, propylparaben and sodium benzoate assay of cough suppressant and a	6
Metabolomic analysis of the sera of patients with the long‐term inhalation of caffeine‐sodium benzoate using LC–MS	6
Protective effects of Typhonii Rhizoma in rheumatoid arthritis rats revealed by integrated metabolomics and network pharmacology	6
Development and Validation of HPTLC Method for Estimation of Podophyllotoxin in Crude Extract, Isolated Podophyllotoxin and Marketed Mother Tincture of	6
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Screening and characterization of cosmetic efficacy components of Terminalia chebula based on biological activity‐guided methodology	6
Green method by National Environmental Methods Index and Eco‐Scale Assessment for evaluation of gatifloxacin‐based product by HPLC	6
Anticoccidial Effects of Tirmania nivea Extract and In Silico Evaluation of Its Phytochemicals Against Eimeria	6
A simple, high‐throughput and validated LC–MS/MS method for the determination of azithromycin in human plasma and its application to a clinical pharmacokinetic study	6
Detection of Pesticide Residues in Fruits and Vegetables Involving Different Chromatographic Techniques (LC–MS/MS, GC–MS/MS, GC and HPLC)	6
A Simple and Sensitive LC‐MS/MS Method for the Determination of Mobocertinib and Its Metabolite Desmethyl‐Mobocertinib in Human Plasma and Its Application to Clinical Pharmacokinetic Study	6
Development, evaluation of critical method variables and stability assessment using a Box–Behnken design for the determination of organic impurities in a pharmaceutical dosage form of a centrally acti	6
Multiple Reaction Monitoring LC‐MS/MS Quantification of N‐Nitrosamine Drug Substance Related Impurities of Clonidine in Drug Substance and in Tablet Dosage Form	6
Comparative analysis of six aconitine‐type alkaloids in decocting extracts between the different processed Fuzi (Aconiti Lateralis Radix praeparata) and its pharmacokinetic behavior in rats by HPLC‐MS	6
Metabolomics study of the hepatoprotective effect of total flavonoids of Mallotus apelta leaf in carbon tetrachloride‐induced liver fibrosis in rats	6
Mechanisms exploration of terrestrosin D on pulmonary fibrosis based on plasma metabolomics and network pharmacology	6
LC–MS/MS determination of HY072808, a novel candidate for treating atopic dermatitis, and its active metabolite: Application to a first‐in‐human pharmacokinetic study	6
Spectrum–effect relationship study between ultra‐high‐performance liquid chromatography fingerprints and anti‐hepatoma effect in vitro of Cnidii Fructus	6
Determination of the dissipative behaviour and final residue of sodium nitrophenol in jujube by liquid chromatography–tandem mass spectrometry	6
Rapid analysis of components in Qizhiweitong tablets and plasma after oral administration in rats by UPLC–Q‐TOF–MS/MS based on a self‐developed database	6
Simultaneous quantification of icaritin and its novel 3‐methylcarbamate prodrug in rat plasma using HPLC–MS/MS and its application to pharmacokinetic study	6
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Study on Quality Evaluation of Processed Cimicifuga Rhizoma Based on UPLC Fingerprint and Chemometrics	6
A Simple, Sensitive, and Stable LC–MS/MS Method for the Simultaneous Determination and Pharmacokinetic Study of Dapagliflozin and Its Metabolite D3OG in Human Plasma	6
A selective, sensitive and fast LC–MS/MS method for cabotegravir quantification in rat plasma and pharmacokinetic investigations	6
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Noval Selective Ligand‐Extraction of Bioactive Components in Complex Natural Products Applying Immobilized Multi‐Target Magnetic Beads	6
Revealing the mechanism of Gualou–Xiebai against myocardial ischemia based on network pharmacology and energy metabolism strategies	6
Dispersive liquid–liquid microextraction and Monte Carlo simulation of margin of safety for octocrylene, EHMC, 2ES, and homosalate in sunscreens	6
Identification of the metabolites of nimbolide in rat by liquid chromatography combined with quadrupole/orbitrap mass spectrometry	6
The JAK2V617F mutation and childhood type1 diabetic nephropathy?	6
A Method for Analysis of Free and Total Ropivacaine in Dog Plasma Using UHPLC–MS/MS	6
A novel LC–MS/MS approach to [19F]‐alfatide and alfatide for application in preclinical pharmacokinetics	6
Development and Validation of the Novel, Fast Bioanalytical LC‐MS/MS Technique for the Simultaneous Estimation of Sotorasib and Ondansetron: Application to In Vivo Pharmacokinetic Assessments	6
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Chemical characterization, multivariate analysis and comparison of biological activities of different parts of Fraxinus mandshurica	6

Effect of Fuzheng Pill on Liver Cancer via the Mitochondrial Apoptosis Pathway	6
Widely Targeted Metabolomics Reveals the Bioactive Metabolites and Antioxidant Activities of Chinese Yam (Dioscorea opposita Thunb.) Peel	6
A Simple Eco‐Friendly Stability‐Indicating HPLC Method for Determination of NETILMICIN in Bulk and Ophthalmic Solution	6
Method validation, dissipation and residue status of fluopicolide and fosetyl‐aluminium in citrus using a rapid extraction method coupled with ultra‐performance liquid chromatography–tandem mass spect	6
Investigation of the Potential Material Basis and Mechanism of Astragali Radix Against Adriamycin‐Induced Nephropathy Model Rat by 1H NMR and MS‐Based Untargeted Metabolomics Analysis	6
Residue levels, household processing evolution, and risk assessment of chlorothalonil, SDS‐3701, metalaxyl, and dimethomorph in Dendrobium officinale Kimura et Migo	6
Unraveling the Mechanisms of Modified Si Miao San in Treating Gouty Arthritis: Network Pharmacology and Experimental Validation	6
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Study on the material basis of Zhujing pill in treating fundus lesions through component analysis and network pharmacology	5
Unraveling the Material Basis of Compound Nanxing Zhitong Plaster: A Multimodal Study Combining Chemical Analysis, Network Pharmacology, and Transdermal Pharmacokinetics	5
First Establishment of LC–MS/MS Method for Quantitative Analysis of Pharmacokinetics and Tissue Distribution of Trilobatin—Comparison of Three Administration Modes	5
Non‐Targeted Metabolomics Analysis of Metabolite Differences in Inocutis tamaricis Under Different Culture Conditions	5
Mechanism of Jinteng Qingbi granules in the treatment of rheumatoid arthritis using metabolomics analysis	5
Determination of six core components from Mahuang Xuanfei Zhike syrup in rat plasma and tissues by UPLC–MS/MS: Application to a pharmacokinetics and tissue distribution study	5
Exploring Potential Targets and Pathways of Toxicity Attenuation Through Serum Pharmacochemistry and Network Pharmacology in the Processing of Aconiti Lateralis Radix Praeparata	5
High‐salt diet contributes to excess oxidative stress and abnormal metabolism in mouse ovaries	5
Preparation, characterization, and pharmacokinetics of oridonin‐loaded liposomes	5
Metabolism of four novel structural analogs of ketamine, 2‐FXE [2‐(ethylamino)‐2‐(2‐fluorophenyl) cyclohexan‐1‐one], 2‐MDCK [2‐(methylamino)‐2‐(o‐tolyl) cyclohexan‐1‐one], 3‐DMXE [2‐(ethylamino	5
Highly sensitive liquid chromatography–mass spectrometry method for the quantitative analysis of mometasone furoate in human plasma: Method validation and application to clinical pharmacokinetic studi	5
Pharmacokinetic study of five components of Fuzheng Huayu tablets in healthy human plasma	5
Analysis of omarigliptin forced degradation products by ultra‐fast liquid chromatography, mass spectrometry, and in vitro toxicity assay	5
Retention behaviour of analytes in reversed‐phase high‐performance liquid chromatography—A review	5
Simultaneous Quantification of Filgotinib and Its Active Metabolite in Human Plasma Using Liquid Chromatography–Tandem Mass Spectrometry: Validation and Clinical Application	5
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Spectrum‐Effect Relationship Between Fingerprints and Anti‐Inflammatory and Antitussive Activities of Raw and Processed Mume Fructus Extracts	5
A simple and sensitive liquid chromatography triple quadrupole mass spectrometry method for the determination of XL092 in monkey plasma and its application to pharmacokinetic study	5
Quantification of Trans‐ and Cis‐Vitamin K1 Isomers in Human Plasma by a Rapid and Sensitive LC–MS/MS Method With Surrogate Matrix	5
Jiedu Tongluo Tiaogan Formula Modulates Glycolipid Metabolism in Type 2 Diabetes via Pyroptosis: Network Pharmacology and In Vivo Analysis	5
Bone and periosteum protein analysis via tandem mass tag quantitative proteomics in pediatric patients with osteomyelitis	5
Preparation of amentoflavone‐loaded DSPE‐PEG2000 micelles with improved bioavailability and in vitro antitumor efficacy	5
Exploring Active Ingredients of Hepatoprotective Effect of Raw and Stir‐Baked Gardeniae Fructus Based on Spectrum–Effect Relationship Analysis	5
Elucidating the mechanisms underlying the anti‐hyperlipidemic effects of Laportea bulbifera using integrated serum metabolomics and network pharmacology	5
Research Progress on the Material Basis of Traditional Chinese Medicines Based on Chemical Biology Methods	5
Investigation Into the Chemical Constituents and Cytotoxic Effects on Lung Cancer Cells of the Rhizomes of Polygonum bistorta L. and Polygonum paleaceum Wall.	5
Assessment of metabolic stability and pharmacokinetics by LC–MS/MS and establishment of the safe dose of IMID‐2, a novel anticancer molecule under drug discovery	5
Pharmacokinetics and bioequivalence studies of fluvoxamine maleate tablets in healthy Chinese subjects	5
A novel standard‐free detection of adulteration method for sildenafil derivatives in dietary supplements	5
In Silico Assessment and Quantitative Estimation of Potential Toxic Impurities From Propafenone (PFN) Through Generic Route and Using UPLC‐MS/MS Technique	5
Superior In Vivo Efficacy of Fermented Over Aqueous Astragalus membranaceus in Diabetic Nephropathy: A Systematic Pharmacological Evaluation and Mechanis	5
Advances in Analytical Strategies for Precise Quantification of Topoisomerase Inhibitors: Current Trends and Future Directions	5
Development of Mobile‐Phase Buffers and Evaluation of Analytical Performance for HbA1c Assays	5
From Chemical Discrepancy to Mechanistic Insight: UPLC‐MS, Bioinformatics, and In Vivo Studies on the Anti‐Brain Aging Effects of Polygalae Radix and Its Processed Products	5
Anti‐rheumatoid arthritis effects of Xanthii Fructus by affecting the PI3K‐AKT signaling pathway based on TMT‐labeled quantitative proteomics	5
Development and validation of a liquid chromatography coupled with tandem mass spectrometry method for determining total and unbound pamiparib in human plasma and brain tumors	5
Fluorescent immunochromatography of vancomycin in plasma: A rapid and sensitive quantitative analysis	5
Correction to “A LC–MS/MS Method for the Simultaneous Determination of 6‐Cyanodopamine, 6‐Nitrodopamine, 6‐Nitrodopa, 6‐Nitroadrenaline and 6‐Bromodopamine in Human Plasma and Its Clinical Application	5
An assessment of the antihyperlipidemic ingredients of Qi Ge Decoction based on metabolomics combined with serum pharmacochemistry	5
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Determination by UHPLC‐QTOF‐HRMS of Phosphatidylethanol (PEth) in Dried Blood Spots: Method Validation and Practical Application of a Rising Alcohol Abuse Biomarker With Minimally Invasive Sampling	5
Integrated pharmacokinetics of Huangqi Jianzhong Tang in normal and chronic atrophic gastritis rats	5
LC–HRMS methods for the quantification of two artemisinin drugs and their metabolites in rat blood and plasma	5
HPLC and GC–MS–based metabolic profiles and in vivo anticonvulsant, sedative, and antinociceptive potentials of truffles Tirmania nivea and Tirmania pinoyi hydromethanolic extracts in mi	5
Trace‐level determination of potential genotoxic impurities in quetiapine fumarate using LC–MS	5
Urinary excretion of silibinin diastereoisomers and their conjugated metabolites in rat and human at different dosages	5
Bioanalytical Tandem Mass Spectrometry Method for Precise Measurement of Tranexamic Acid in Human Plasma With Unveiling Methodological Advancement: Green Assessment With Advanced Metrics	5
Olanzapine‐induced weight gain and lipid dysfunction in mice between different gender	4
Analytical method for urinary homovanillic acid and 5‐hydroxyindoleacetic acid levels using HPLC with electrochemical detection applied to evaluate children environmentally exposed to manganese	4
A Simultaneous Determination of 14 Chemical Compounds From Rubi Fructus in Rat Plasma by UHPLC‐QTR	4
Research progress in the application of proteomics technology in brain injury	4
Quantification of 3‐bromopyruvate in rat plasma by HPLC–MS/MS employing precolumn derivatization and the application to a pharmacokinetics study	4
Differential metabolic profiles of ginsenosides in artificial gastric juice using ultra‐high‐pressure liquid chromatography coupled with linear ion trap‐Orbitrap mass spectrometry	4
Bioanalytical methods for pharmacokinetic studies of antileishmanial drugs	4
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HPLC‐MS/MS Method for the Simultaneous Quantification of SGLT2 Inhibitor YWS22026 and Its M3 Metabolite in Rat Plasma, With Application to Toxicokinetic Study	4
Therapeutic drug monitoring of free vancomycin concentration in practice: A new analytical technique based on the HFCF–UF sample separation method	4
Advances in mass spectrometry for metabolomics: Strategies, challenges, and innovations in disease biomarker discovery	4
Residue levels of emamectin benzoate, imidacloprid and its major metabolites in cabbage from 12 regions in China and dietary risk assessment	4
Optimization of a HPLC–UV bioanalytical method using Box–Behnken design to determine the oral pharmacokinetics of neratinib maleate in Wistar rats	4
Chromatographic authentication of botanical origin: Herbaceous pollen profiling with HPLC, HPTLC and GC–MS analysis	4
Urine metabolomic characteristics of female patients with occupational chronic cadmium poisoning after 15 years of treatment	4
Simultaneous determination of four fungicide residues in figs using liquid chromatography tandem mass spectrometry	4
Preclinical pharmacokinetics and metabolism study of SCO‐267, a GPR40 full agonist, in beagle dogs using ultra‐high performance liquid chromatography coupled to tandem mass spectrometry	4
Validated HPLC‐UV Detection Method for Cefiderocol Quantification in a Critical Patient Receiving Fetcroja and Treated With Extracorporeal Replacement Therapies	4
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Sorption and mobility assessment of tembotrione in soils of upper, trans and middle Gangetic plain zones of India	4
Study on the Relationship Between HPLC Fingerprint Profiles and Anti‐Inflammatory Activity of Clinopodii Herba	4
Stability‐indicating liquid chromatography method development for assay and impurity profiling of amitriptyline hydrochloride in tablet dosage form and forced degradation study	4
Integrating Metabolomics and Serum Pharmacochemistry to Reveal Potential Hemostatic Components and Processing Mechanisms of Carbonized Typhae Pollen	4
Determination of valproic acid and its six metabolites in human serum using LC–MS/MS and application to interaction with carbapenems in epileptic patients	4
Development and validation of LC–MS/MS methods for the simultaneous quantification of sofosbuvir and its major metabolite (GS‐331007) in blood plasma and cerebrospinal and seminal fluid: Application t	4
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Serum metabolic profile evidence for relationship between schizophrenia and depression: An untargeted metabolomics	4
A green approach for the analysis of emtricitabine bictegravir and tenofovir in a pharmaceutical preparation using novel HPLC and spectrophotometric methods	4
Gas chromatography mass spectrometer determination of dimethylamine impurity in N,N‐dimethylformamide solvent by derivatization of N,N‐dimethylbenzamide with benzoyl chlori	4
Integrated UHPLC‐Q‐TOF‐MS Technology and Network Pharmacology Exploring the Pharmacodynamic Material Basis and Mechanism of Zhi‐Zi‐Hou‐Po Granule for Treatment of Depression–Anxiety Comorbidity	4
Simultaneous determination and quality evaluation of 16 compounds in Ligustri Lucidi Fructus covering different regions and processed products using ultra‐high‐performance liquid chromatography‐mass s	4
Establishing a multi‐method approach for unprecedented detection and quantification of 13 genotoxic impurities (GTIs) in Apixaban drug substance through ultra‐performance liquid chromatography (UPLC)	4
Simultaneous determination of nirmatrelvir and ritonavir in human plasma using LC–MS/MS and its pharmacokinetic application in healthy Chinese volunteers	4
A comparative metabolomics study on dried and processed Rehmannia Radix	4
Comprehensive Proteomic and Metabolomic Analysis of Novel Substituted Fluoroquinolone Derivatives in Escherichia coli	4
Optimizing Mirabegron Stability in Human Plasma: Method Development, Validation Through Integration of Esterase Inhibitors and Stabilizers	4
Analysis of blood concentrations and clinical application of risdiplam in patients with spinal muscular atrophy using ultra‐high performance liquid chromatography–tandem mass spectrometry	4
Identification and Multidimensional Evaluation of Quality Markers in Yupingfeng via UPLC‐Q‐Orbitrap‐MS, Network Pharmacology, UPLC‐UV Fingerprint, and UPLC‐QQQ‐MS	4
Metabolite profiling of remibrutinib in rat and human liver microsomes using liquid chromatography combined with benchtop orbitrap high‐resolution mass spectrometry	4
Application of QbD‐based approach to the development and validation of an RP‐HPLC method for simultaneous estimation of pregabalin and naringin in dual‐drug loaded liposomes	4