OOIR: Observatory of International Research

Papers

(The median citation count of Biomedical Chromatography is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Monitoring and method validation of organophosphorus/organochlorine pesticide residues in vegetables and fruits by gas chromatography	37
Optimization, extraction, and purification of three bioactive compounds from Entada phaseoloides by high‐speed countercurrent chromatography	35
Determination of fingerprints contents of different extracts and parts of six endemic Salvia taxa by GC–MS: Source species for valuable compounds with drug or drug potential	28
A metabolic investigation of arterialized venous flaps in rabbits using mass spectrometry‐based metabolomics	27
Issue Information	26
Pharmacokinetic studies of ginsenosides Rk1 and Rg5 in rats by UFLC–MS/MS	25
A review of various analytical methods for the estimation of olanzapine: An antipsychotic drug	25
US FDA–validated TLC method with four greenness assessment evaluations for simultaneous determination of prednisolone and esomeprazole in spiked human plasma	23
Investigation of the apoptosis‐inducing effect of docetaxel by comprehensive LC–MS–based metabolomics and network pharmacology approaches	23
Greenness profile assessment of selective liquid chromatographic methods for determination of a quaternary antimigraine combination along with three of their related official impurities	22
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Sample pretreatment and HPLC determination of antiplatelet drug ticagrelor in blood plasma from patients with acute coronary syndromes	21
Metabolism, pharmacokinetics, and bioavailability of yuanhuacine in rat using LC–MS	20
Ellagic acid from pomegranate peel: Consecutive countercurrent chromatographic separation and antioxidant effect	20
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Widely targeted metabolomics analysis reveals the differences in nonvolatile compounds of citronella before and after drying	18
Recent advances in the chromatographic determination of the most commonly used anti‐hepatitis C drug sofosbuvir and its co‐administered drugs in human plasma	17
A novel method for the quantification of anlotinib in human plasma using two‐dimensional liquid chromatography	17
Highly sensitive and selective detection of cytochrome P450 46A1 activity by a ultra‐high‐performance liquid chromatography–tandem mass spectrometry method	16
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A sensitive and efficient LC–MS/MS method for the bioanalysis of fosinopril diacid from human plasma and its application for a bioequivalence study in humans	15
Preparation of 5‐hydroxymethylfurfural from Schisandra chinensis (Turcz.) Baill by high‐speed counter‐current chromatography: Comparison of conventional and consecutive separation	15
Ultra‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry–based plasma metabolomics study of hepatoprotective effect of cuscutae semen on CCl₄‐induced liver injury	14
Metabolite profiles of Gansuibanxia decoction in rat plasma and urine by UHPLC‐Q‐TOF/MS analysis	14

Quality by design with design of experiments approach for development of a stability‐indicating LC method for enzalutamide and its impurities in soft gel dosage formulation	14
Development and validation of a sensitive LC‐MS/MS method for simultaneous analysis of clopidogrel and simvastatin and their main metabolites in beagles: Application to pharmacokinetic drug interactio	14
High‐resolution mass spectrometry‐based methodology for the identification of the metabolites of pterostilbene produced by rat, dog and human hepatocytes	14
Gas chromatography mass spectrometer determination of dimethylamine impurity in N,N‐dimethylformamide solvent by derivatization of N,N‐dimethylbenzamide with benzoyl chlori	14
A new method providing complementary explanation of the blood‐enriching function and mechanism of unprocessed Angelica sinensis and its four kinds of processed products based on tissue‐integrat	14
Cell metabolomics study on synergistic anti‐hepatocellular carcinoma effect of Aidi injection combined with doxorubicin	14
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Does bisphenol A bioaccumulate on zebrafish? Determination of tissue bisphenol A level	13
Development of an efficient stability‐indicating LC–MS/MS method for the analysis of selexipag and characterization of its degradation products	13
Development and optimization of a high‐throughput HPLC–MS/MS method for the simultaneous determination of naringenin and its valine carbamate prodrug in rat plasma	13
Encapsulation of gingerol into nanoliposomes: Evaluation of in vitro anti‐inflammatory and anti‐cancer activity	12
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Pharmacokinetics of IMM‐H012 in rats using ultra‐performance liquid chromatography‐tandem mass spectrometry	12
Determination of 23 related analytes in bone marrow fluid and hippocampus of C57BL/6 mice following cerebral ischemia–reperfusion injury by HPLC‐FLD	12
Lipidomics reveals the serum profiles of pediatric allergic rhinitis and its severity	12
Development of a simultaneous quantification method of imatinib and sunitinib and their main metabolites and its application in patients with gastrointestinal stromal tumor	11
Pharmacokinetics, tissue distribution, and plasma protein binding ratio of bicuculline following intragastric and intravenous administration in rats using ultra‐high‐performance liquid chromatography–	11
Risk assessment, development and validation of a GC‐ECD‐based method for the quantification of cypermethrin from green pea	11
Ultra‐high‐performance liquid chromatography–quadrupole time of flight tandem mass spectrometry based in vitro metabolite profiling of DK‐GV‐04P, a novel anticancer molecule under drug discover	11
Chromatographic assessment of biodiesel production from Peganum harmala seed oil using environmentally benign nano‐catalysts	11
Rapid haemoglobin A and S quantification using Tosoh HLC‐723G8 in variant mode for patients with sickle cell disease	11
Matrix effect in bioanalytical assay development using supercritical fluid chromatography‐mass spectrometry	11
A novel strategy on the spectrochromatographic analysis of a quaternary mixture by parallel factor analysis model	10
Structure of crude polysaccharides from Atractylodes lancea rhizome and treatment of diarrhea owing to spleen deficiency through intestinal flora	10
Effects of vitamin C on the pharmacokinetics and pharmacodynamics of nimodipine in rats	10
Development of a novel quality by design–enabled stability‐indicating HPLC method and its validation for the quantification of nirmatrelvir in bulk and pharmaceutical dosage forms	10
Development of stability‐indicating assay method and liquid chromatography‐quadrupole‐time‐of‐flight mass spectrometry‐based structural characterization of the forced degradation products of alpelisib	10
Antileukemic effects of indigo naturalis constituents by “target constituent knock‐out” coupled with semipreparative liquid chromatography and quadrupole time‐of‐flight mass spectrometry	10
Multimodal integrated strategy for the discovery and identification of antiplatelet aggregation Q‐markers in Paris polyphylla var. yunnanensis	10
The variation in the levels of 18 amino acids in the cortex and plasma of cerebral ischemia C57BL/6 mice	10
Unique liquid chromatography technique for the determination of mirabegron in the presence of polymers; robustness by Design Expert in the light of Quality by Design	10
Development of stability‐indicating method for separation and characterization of benidipine forced degradation products using LC–MS/MS	10
Comparative analysis of excretion of six major compounds of Polygonum orientale L. extract in urine, feces and bile under physiological and myocardial ischemia conditions in rats usi	10
Chemical‐activity‐based quality marker screening strategy for Viscum articulatum	10
Validated LC–MS/MS method for the determination of copanlisib in mouse dried blood spots	10
Development of simultaneous quantitative analytical method for metabolites of hexosamine biosynthesis pathway in lung cancer cells using ultra‐high‐performance liquid chromatography‐tandem mass spectr	9
Dissipation pattern and dietary risk assessment of chlorfenapyr and methomyl in corn under Egyptian field conditions	9
Investigate the effect of honey on the absorption of seven active ingredients from wu‐tou decoction in rats	9
Combining network pharmacology with chromatographic fingerprinting and multicomponent quantitative analysis for the quality evaluation of Astragali Radix	9
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Revealing the optimal traditional processing methods and its protective effects against febrile seizures of Arisaema cum bile	9
Oral solid dosage form using alternate crystalline neratinib maleate anhydrous form: Pharmaceutical, bioequivalent, and clinical perspectives	9
LC–MS/MS approach for simultaneous assessment of hyoscine N‐butyl bromide and ketoprofen in biological fluids and pharmaceuticals	9
The antitumor activity and pharmacokinetics research of PPD‐Arg (Tos) using ultra‐performance liquid chromatography‐quadrupole‐time‐of‐flight mass spectrometry	9
Tandem mass tag‐based proteomics reveals the antiepileptic mechanism of steroidal saponins from Anemarrhena asphodeloides in Kainic acid induced epileptic rat model	9
Absorption characteristics of ilexgenin A and ilexsaponin B1 in human umbilical vein endothelial cells after administration of the total triterpenoid saponins from Ilex pubescens	9
Combining network pharmacology with chromatographic fingerprinting and multicomponent quantitative analysis for the quality evaluation of Moutan Cortex	9
Untargeted metabolomics reveals potential plasma biomarkers for diagnosis of primary aldosteronism using liquid chromatography–mass spectrometry	8
A metabolism‐based study of the mechanism of action of Scrophularia ningpoensis Hemsl. on nephrogenic edema	8

Response surface methodology optimization of extraction and enrichment conditions of total triterpenoid saponins from Celosiae Semen and evaluation of its lipid‐lowering activity	8
Improved LC–MS/MS method for the simultaneous quantification of tacrolimus and cyclosporine A in human blood and application to therapeutic drug monitoring	8
Residue levels and risk assessment of acetamiprid–pyridaben mixtures in cabbage under various open field conditions	8
Serum metabolomics analysis combined with network pharmacology reveals possible mechanisms of postoperative cognitive dysfunction in the treatment of Mongolian medicine Eerdun Wurile basic formula	8
A new method for detecting Na⁺, K⁺‐ATPase activity by ICP–MS: Quantitative analysis on the inhibitory effect of rhein on Na⁺, K⁺‐ATPase activity by ICP–MS i	8
High‐throughput UPLC‐Q‐TOF‐MS/MS coupled with multivariable data processing approach for the rapid screening and characterization of chemical constituents and potential bioactive compounds from Danggu	8
Validated HPLC‐UV method for amphotericin B quantification in a critical patient receiving AmBisome and treated with extracorporeal replacement therapies	8
Comparative metabolomics and lipidomics study to evaluate the metabolic differences between first‐ and second‐generation mammalian or mechanistic target of rapamycin inhibitors	8
A universal surrogate matrix assay for urea measurement in clinical pharmacokinetic studies of respiratory diseases	8
Preparation, characterization and wound‐healing effect of PEGylated nanoliposomes loaded with oleuropein	8
Protective effect of Clinacanthus nutans in cisplatin‐induced nephrotoxicity on human kidney cell (PCS‐400‐010) elucidated by an LCMS‐based metabolomics approach	8
An UHPLC–QTOF–MS‐based strategy for systematic profiling of chemical constituents and associated in vivo metabolites of a famous traditional Chinese medicine formula, Yinchenhao decoction	7
An untargeted serum and urine lipidomics research based on UPLC–MS revealed the lipid alterations on adjuvant‐induced arthritis rats	7
Quantitative determination of LY‐404,039, a metabotropic glutamate 2/3 receptor agonist, in rat plasma using chemical derivatization and HPLC–MRM/MS	7
Dissipation, adsorption–desorption, and potential transformation products of pinoxaden in soil	7
Development and validation of a ultraperformance liquid chromatography–tandem mass spectrometry method for quantifying free and total dabigatran in human plasma: An application for a bioequivalence st	7
Study on the material basis of Dahuang Zhechong pill of anti‐hepatoma effect by promoting vascular normalization	7
A new method based on dispersive liquid–liquid microextraction for fat‐soluble vitamin determination in serum by LC–MS/MS	7
An ultrahigh‐performance liquid chromatography–tandem mass spectrometry method for quantification of methotrexate and 7‐hydroxy‐methotrexate and application for therapeutic drug monitoring in patients	7
Evaluation of the effects of notoginseng total saponins (NS), safflower total flavonoids (SF), and the combination of NS and SF (CNS) on the activities of cytochrome P450 enzymes using a cocktail meth	7
Preparative separation of six compounds from Salvia yunnanensis Radix using pH‐zone‐refining counter‐current chromatography	7
Validation of a bioanalytical HPLC–UV method to quantify Α‐Bisabolol in rat plasma applied to pharmacokinetic pilot study with the drug nanoemulsion	7
Low‐level determination of 4‐chlorobutyl‐(S)‐[4‐chloro‐2‐(4‐cyclopropyl‐1,1,1‐trifluoro‐2‐hydroxy‐but‐3yn‐2‐yl)phenyl] carbamate (4‐CTHC) in efavirenz drug substance by LC–MS	7
Simultaneous determination of four fungicide residues in figs using liquid chromatography tandem mass spectrometry	7
Determination of flurbiprofen in rat plasma using ultra‐high performance liquid chromatography–tandem mass spectrometry and its application in a pharmacokinetic study	7
Chemical composition, antifungal and antibiofilm activities of essential oils from Glycyrrhiza foetida (Desf.) growing in Tunisia	7
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Detection and identification of imperatorin metabolites in rat, dog, monkey, and human liver microsomes by ultra‐high‐performance liquid chromatography combined with high‐resolution mass spectrometry	7
Establishment and validation of an SIL‐IS LC–MS/MS method for the determination of ibuprofen in human plasma and its pharmacokinetic study	7
Determination and tissue distribution comparisons of five xanthones after orally administering crude and processed gamboge	7
Covalent organic frameworks and related innovative materials in chiral separation and recognition	6
Microwave‐assisted extraction of bioactive components from Angelica dahurica using the tailor‐made natural deep eutectic solvents	6
Unique biomedical application of fluorescence derivatization based on palladium‐catalyzed coupling reactions for HPLC analysis of pharmaceuticals and biomolecules	6
Chemical profile and difference analysis of four parts of Strobilanthes sarcorrhiza by ultrafast flow liquid chromatography coupled with quadrupole‐time‐of‐flight mass spectrometry and multivar	6
Nontargeted metabolomics reveals sequential changes in amino acid and ferroptosis‐related metabolism in Parkinson's disease	6
A RP‐HPLC–DAD method for analysis of Brazilian southeast brown propolis and its leishmanicidal properties	6
Pharmacognostic standardization and machine learning–based investigations on Akebia quinata and Akebia trifoliata	6
Serum metabolic profile evidence for relationship between schizophrenia and depression: An untargeted metabolomics	6
Identification and characterization of two new oxidation degradation impurities in cinnarizine through LC‐HRMS/MS and ¹H NMR, along with in silico toxicity predictions of its degradation pr	6
Mango peel extracts and mangiferin chromatographic Fourier‐transform infrared correlation with antioxidant, antidiabetic, and advanced glycation end product inhibitory potentials using in silico model	6
Comparative pharmacokinetics study of six effective components between two dosage forms of Qixue–Shuangbu Prescription in rats by UPLC–MS/MS	6
Quantification of 3‐bromopyruvate in rat plasma by HPLC–MS/MS employing precolumn derivatization and the application to a pharmacokinetics study	6
Proteomic analysis of exosomal proteins associated with bone healing speed in a rat tibial fracture model	6
Development and validation of an HPLC coupled with tandem mass spectrometry method for the determination of HSK7653, a novel super long‐acting dipeptidyl peptidase‐4 inhibitor, in human plasma and uri	6
Enhancing effect of borneol on pharmacokinetics of ginsenoside Rb₁, ginsenoside Rg₁, and notoginsenoside R₁ in healthy volunteers after oral administration of compound	6
Stability‐indicating RP‐HPLC method development and validation for the quantification of amlodipine besylate and valsartan tablets in solid oral dosage form	6
Evaluation of various polysaccharide‐based stationary phases for enantioseparation of chloro‐containing derivatives in normal phase liquid chromatography	6
The pharmacokinetics and tissue distribution of curcumin following inhalation administration in rats—A comparative analysis with oral and intravenous routes	6
An observation study of urinary biomarker exploratory in Alzheimer's disease using high‐resolution mass spectrometry	6
Development, validation, and implementation of an UHPLC–MS/MS method for the quantitation of furosemide in infant urine samples	6
Screening of polysaccharides from the differently processed products of Angelica sinensis with the best liver protection effect on chicken and the intervention mechanism study based on tandem m	6
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Dissipation pattern and dietary risk assessment of some commonly used insecticides on tomato (Solanum lycopersicum L.)	6
Method development and validation of an analytical quality by design ultrafast liquid chromatographic method for the determination of bedaquiline from pharmaceutical bulk and nanoemulsions	6
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Impact of different processing methods of Ligustrum lucidum Ait. on kidney‐yin deficiency: a study based on pharmacodynamics and metabolomics research	5
A novel anastrozole intravaginal ring for endometriosis: Pharmacokinetic characteristics and mucosal irritation	5
Dissipation kinetics, risk assessment, and waiting period of spiromesifen on chili fruits using gas chromatography–electron capture detector	5
Simultaneous determination of nirmatrelvir and ritonavir in human plasma using LC–MS/MS and its pharmacokinetic application in healthy Chinese volunteers	5
Urinary phenylethylamine metabolites as potential markers for sports drug testing purposes	5
Characterization and Analytical Method Validation for Potential Impurities of a Merchantability Drug Substance Fluoxetine HCl	5
Changes in the essential oil content and composition of Salvia limbata C.A. Mey at different growth stages and altitudes	5
A simple and sensitive high‐performance liquid chromatographic method combined with fluorescence detection for bioanalysis of scopoletin in rat plasma: Application to a pharmacokinetic study	5
Development of a Pteris vittata L. compound database by widely targeted metabolomics profiling	5
A Validated Liquid Chromatography–Tandem Mass Spectrometry Method for the Determination of Methylophiopogonanone A in Rat Plasma and Its Application to Pharmacokinetic Study	5
Dual‐target affinity analysis and separation of α‐amylase and α‐glucosidase inhibitors from Morus alba leaves using a magnetic bifunctional immobilized enzyme system	5
A rapid and sensitive LC–MS/MS method for the determination of vanillic acid in rat plasma with application to pharmacokinetic study	5
Method validation, residue analysis and dietary risk assessment of trifloxystrobin and trifloxystrobin acid in milk, eggs and pork	5
A QbD‐led simple and sensitive RP‐UHPLC method for simultaneous determination of moxifloxacin, voriconazole, and pirfenidone: An application to pharmaceutical analysis	5
Development, validation, and clinical application of a rapid UPLC–MS/MS method for detection of colchicine in human whole blood and urine	5
Rapid screening of α‐glucosidase inhibitors in Hypericum perforatum L. using bio‐affinity chromatography coupled with UPLC/MS	5
Simultaneous determination of monocrotaline and its N‐oxide metabolite in rat plasma using LC–MS/MS: Application to a pharmacokinetic study	5
Differences between novel hybrid mode flaps and traditional perforator flaps at the level of metabolites using LC–MS	5
Screening 5‐lipoxygenase inhibitors from selected traditional Chinese medicines and isolation of the active compounds from Polygoni Cuspidati Rhizoma by an on‐line bioactivity evaluation system	5
Highly Sensitive LC–MS/MS Method for Determination of Dexamethasone in Rat Plasma and Brain Tissue: An Application to Pharmacokinetic Study in Rats	5
A state‐of‐the‐science review of analytical methods for urinary dialkylphosphate metabolites in the assessment of exposure to organophosphate pesticides: From 2000 to 2022	5
Evaluation of green and efficient deep eutectic solvents as media for extracting alkaloids from lotus leaf	5
Validation of a robust and rapid liquid chromatography tandem mass spectrometric method for the quantitative analysis of navitoclax	5
Assessment of the anticancer potential of certain phenolic and flavonoid components in ginger capsules using colorectal cancer cell lines coupled with quantitative analysis	5
Screening and Verification of Blood‐Activating Effective Component Group of Panax notoginseng Based on Spectrum–Effect Relationships	5

A novel UPLC–MS/MS method for simultaneous quantification of trigonelline, 4‐hydroxyisoleucine, and diosgenin from Trigonella foenum‐graecum extract: Application to pharmacokinetic s	5
In vivo detection of the epimer metabolites of sweroside via ultra‐performance liquid chromatography time‐of‐flight mass spectrometry combined with DNPH derivatization	5
A membrane solid‐phase extraction method based on MIL‐53‐mixed‐matrix membrane for the determination of estrogens and parabens: Polyvinylidene difluoride membrane versus polystyrene‐block‐polybutadien	5
Evaluating the behavior and principle of deep eutectic solvent on ephedrine‐type alkaloid extraction from Ephedrae Herba	5
Pharmacokinetics, tissue distribution, and excretion study of GL‐V9 and its glucuronide metabolite 5‐O‐glucuronide GL‐V9 in Sprague–Dawley rats	5
Screening ofBletilla striata,Bletilla ochraceaandOreorchis foliosadifferential metabolites based on metabolomics	5
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Pharmacokinetic study of iptacopan and its two acyl glucuronide metabolites in monkey plasma by liquid chromatography combined with electrospray ionization tandem mass spectrometry	5
Dynamic Metabolic Characterization of Lung Tissues in Rats Exposed to Whole‐Thorax Irradiation Based on GC‐MS	5
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A novel stability‐indicating HPLC method for the determination of enantiomeric purity of eluxadoline drug: Amylose tris(3,5‐dichlorophenyl carbamate) stationary phase	5
Novel analytical approach for baclofen quantification in rodent plasma	5
A simple and sensitive ultra‐high performance liquid chromatography tandem mass spectrometry method for the quantitative analysis of VX‐548 in monkey plasma: Method validation and application to pharm	5
Combination of omics, bioinformatics, molecular docking, and experimental validation to elucidate the hepatoprotective effects, mechanisms, and active compounds of Shandougen	5
Unique Research for Developing a Full Factorial Design Evaluated Liquid Chromatography Technique for Estimating Budesonide and Formoterol Fumarate Dihydrate in the Presence of Specified and Degradatio	5
A rapid and convenient sample preparation method for the analysis of cannabinoids in oral fluid samples	5
Development and validation of LC–QTOF–MS/MS method for the identification and determination of low levels of a genotoxic impurity, 4,6‐dichloro‐5‐nitro‐2‐(propylthio)pyrimidine in ticagrelor API	5
Inhibition of human UDP‐glucuronosyltransferase enzyme by Dabrafenib: Implications for drug–drug interactions	5
Isolation and characterization of Newcastle disease virus from biological fluids using column chromatography	5
Pharmacokinetics and tissue distribution of cantharidin after oral administration of aqueous extracts from Mylabris in rats	5
A metabolomics study on the mechanisms of Gardeniae fructus against α‐naphthylisothiocyanate‐induced cholestatic liver injury	5
Analytical method for urinary homovanillic acid and 5‐hydroxyindoleacetic acid levels using HPLC with electrochemical detection applied to evaluate children environmentally exposed to manganese	5
Liquid chromatography coupled with tandem mass spectrometry for simultaneous quantification of valproate, valproate‐glucuronide and lamotrigine in various biological matrices of rat	5
Development and application of a novel LC–MS/MS method for human plasma concentration monitoring of perampanel in pediatric epilepsy patients	5
Toxicokinetic and bioavailability studies on retrorsine in mice, and ketoconazole‐induced alteration in toxicokinetic properties	5
Simultaneous Determination of Vitamins A and E and Their Generated Metabolites in Human Serum by LC–MS/MS	5
Comparison of the Antioxidant Capacity of Cell Wall‐Broken Decoction Pieces and Traditional Decoction Pieces of Astragli Radix Based on HPLC‐ABTS Analytical Method	5
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Dissipation kinetics, residue determination and consumer risk assessment of acephate on green pea by gas chromatography–electron capture detector	4
UPLC/Q‐TOF–MS‐based metabolomics and molecular docking analysis of Bifidobacterium adolescentis exposure to levofloxacin	4
Integrating metabolomics and bioinformatics to reveal the mechanism of Epimedium‐induced liver injury	4
A green approach for the analysis of emtricitabine bictegravir and tenofovir in a pharmaceutical preparation using novel HPLC and spectrophotometric methods	4
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Eco‐friendly liquid chromatography method for the quantification of ibrutinib in a pharmaceutical dosage form	4
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Dried blood spot as an alternative sample for screening of fatty acid, amino acid, and keto acid metabolism in humans	4
Fast determination of free metronidazole in rat plasma and peritoneal fluid using HPLC‐UV method	4
Deciphering the chemical composition of Ganoderma lucidum from different geographical origins by mass spectrometry molecular networking coupled with multivariate analysis	4
A solid‐phase microextraction gas chromatography–mass spectrometry technique for urinary metabolomics of human samples infected with schistosomiasis—Case of the Okavango Delta, Botswana	4
Optimization and validation of high‐performance liquid chromatography using modified QuEChERS to determine anthelmintic drugs in mutton	4
Development of a joint derivatization protocol for the unequivocal identification of the monosaccharide composition in four dendrobium polysaccharides and free monosaccharide by GC–MS	4
Molecular mechanism of Xiaohuoluo wan for rheumatoid arthritis by integrating in vitro and in vivo chemomics and network pharmacology	4
Simple determination of urine cefazolin concentration in pediatric patients with urinary tract infections using high‐performance liquid chromatography	4
Anti‐fibrosis attributes: UHPLC‐MS/MS‐based pharmacokinetics profiling of a novel autotaxin inhibitor with excellent in vivo efficacy in rat	4
Plasma metabolites and inflammatory proteins profiling predict outcome of Fufang Duzhong Jiangu granules treating Kashin–Beck disease	4
Olanzapine‐induced weight gain and lipid dysfunction in mice between different gender	4
Development and validation of an LC–MS/MS method for simultaneous determination of remdesivir and its hydrolyzed metabolite and nucleoside, and its application in a pharmacokinetic study of normal and	4
Insight gained via ultra‐performance liquid chromatography tandem mass spectrometry‐based metabolomics: Protective effect of Artemisia argyi H.Lév. & Vaniot essential oil on lipopolysacchar	4
Delineation of prototypical degradation mechanism, characterization of unknown degradation impurities by liquid chromatography–quadrupole‐time‐of‐flight–tandem mass spectrometry and stability‐indicati	4
Verification studies of tryptophan and kynurenine determination using HPLC and evaluation of the kynurenine pathway and neopterin levels in human colostrum samples	4
A rapid and sensitive LC–MS/MS method for quantifying oxycodone, noroxycodone, oxymorphone and noroxymorphone in human plasma to support pharmacokinetic drug interaction studies of oxycodone	4
Pharmacokinetic study of deufruquintinibs in rats by HPLC–MS/MS after oral administration	4
Electrophoretic deposition of polyaniline nanofibers on a stainless steel wire as an adsorbent for determination of tamoxifen by SPME/GC–FID in urine samples	4
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Development of an UHPLC–MS/MS method to determine cutaneous biodistribution of cannabidiol after topical application of cannabidiol gel assisted by iontophoresis	4
RP‐HPLC method development, validation and pharmacokinetic applicability in preclinical evaluation of rhein treated with novel diacerein eutectics	4
Mycotoxin detection in selected medicinal plants using chromatographic techniques	4
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In vivo pharmacokinetic study of vanillic acid in monocrotaline‐induced pulmonary arterial hypertension rats and its tissue distribution	4
Establishment and validation of a sensitive LC–MS/MS method for the quantification of KRAS^G12C protein PROTAC molecule LC‐2 in rat plasma and its application to in vivo pharmacokinet	4
Simultaneous determination of five compounds of fried Radix Paeoniae Alba extract in beagle dogs plasma by Ultra Performance Liquid Chromatography Tandem Mass Spectrometry and its application in a pha	4
Synchronized determination of sacubitril and valsartan with some co‐administered drugs in human plasma via UPLC–MS/MS method using solid‐phase extraction	4
Development and validation of a liquid chromatography–tandem mass spectrometry method for the quantification of the acetyl‐coenzyme A competitive p300/CBP catalytic inhibitor A‐485 in biological sampl	4
Phytochemical analysis and hepatotoxicity assessment of braised Polygoni Multiflori Radix (Wen‐He‐Shou‐Wu)	4
Chromatographic analysis and antioxidant potency of the crude extract of Xanthium spinosum in various fractions	4
A review of extraction methods and analytical techniques for styrene and its metabolites in biological matrices	4
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Acoustic ejection mass spectrometry: Development, applications, and future perspective	4
Research progress in the application of proteomics technology in brain injury	4
Integrating serum metabolomics analysis and network pharmacology to reveal the potential mechanism of Shengmai Jianghuang San in the treatment of nasopharyngeal carcinoma	3
TMT‐based proteomics analysis of the effects of Qianjinweijing Tang on lung cancer	3
Determination of three C18‐oxygenated steroids in adrenal lesion segments in primary aldosteronism by super‐selective adrenal venous sampling and LC/ESI–MS/MS	3
Pharmacokinetic and pharmacodynamic herb–drug interactions of common over‐the‐counter pain medications	3
Determination of valproic acid and its six metabolites in human serum using LC–MS/MS and application to interaction with carbapenems in epileptic patients	3
A highly sensitive method (supercritical fluid chromatography coupled with ion mobility mass spectrometry) for determination of multiple compounds in radix curcumae	3
Identification of anti–hepatic fibrosis components in Periplaneta americana based on spectrum–effect relationship and chemical component separation	3
Development of a simultaneous analytical method for clozapine and its metabolites in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry with linear range adjuste	3
Simultaneous quantification of caffeine and its main metabolites by gas chromatography mass spectrometry in horse urine	3
Investigation of the therapeutic effect of Hedan tablets on high‐fat diet‐induced obesity in rats by GC–MS technology and 16S ribosomal RNA gene sequencing	3
Differential metabolic profiles of ginsenosides in artificial gastric juice using ultra‐high‐pressure liquid chromatography coupled with linear ion trap‐Orbitrap mass spectrometry	3
The potential mechanism of Choulingdan mixture in improving acute lung injury based on HPLC–Q‐TOF–MS, network pharmacology and in vivo experiments	3
Ultra‐high‐performance liquid chromatography‐tandem mass spectrometry‐based metabolomics unveils the metabolic alterations in colon cancer mice during CT‐guided radiofrequency ablation	3
Dynamic changes in chemical compositions and anti‐acetylcholinesterase activity associated with steaming process of stem‐leaf saponins of Panax notoginseng	3
Based on UHPLC–Q‐TOF–MS and bioinformatics strategies, the potential allergens and mechanisms of allergic reactions caused by Danshen injection were explored	3
Integrating network pharmacology and renal metabonomics to reveal the protective mechanism of resveratrol on gouty nephropathy	3
Identification of ginsenoside metabolites in plasma related to different bioactivities of Panax notoginseng and Panax ginseng	3
Metabolite profiling of IMID‐2, a novel anticancer molecule of piperazine derivative: In silico prediction, in vitro and in vivo metabolite characterization using UPLC–QTOF–MS/MS	3
A LC–MS/MS method for the simultaneous determination of 6‐cyanodopamine, 6‐nitrodopamine, 6‐nitrodopa, 6‐nitroadrenaline and 6‐bromodopamine in human plasma and its clinical application in patients wi	3
Assessment of brain‐to‐blood drug distribution using liquid chromatography	3
Determination, residue analysis, dietary risk assessment, and processing of flupyradifurone and its metabolites in pepper under field conditions using LC–MS/MS	3