OOIR: Observatory of International Research

Papers

(The median citation count of Biomedical Chromatography is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
A novel, rapid and simple UPLC–MS/MS method for quantification of favipiravir in human plasma: Application to a bioequivalence study	37
A Quality by Design and green LC technique for the determination of mast cell stabilizer and histamine receptor antagonist (Olopatadine HCl) in multiple formulations	32
Derivatization procedures and their analytical performances for HPLC determination in bioanalysis	27
Metabolomics and correlation network analysis of follicular fluid reveals associations between l‐tryptophan, l‐tyrosine and polycystic ovary syndrome	26
Recent applications of microextraction sample preparation techniques in biological samples analysis	25
Quality evaluation of rhubarb based on qualitative analysis of the HPLC fingerprint and UFLC–Q‐TOF–MS/MS combined with quantitative analysis of eight anthraquinone glycosides by QAMS	25
Accelerated stability study of the ester prodrug remdesivir: Recently FDA‐approved Covid‐19 antiviral using reversed‐phase‐HPLC with fluorimetric and diode array detection	25
Liquid chromatography–mass spectrometry applications for quantification of endogenous sex hormones	23
Chemical constituents of radix Actinidia chinensis planch by UPLC–QTOF–MS	23
Quality by design with design of experiments approach for development of a stability‐indicating LC method for enzalutamide and its impurities in soft gel dosage formulation	22
High‐performance thin‐layer chromatography based approach for bioassay and ATR–FTIR spectroscopy for the evaluation of antioxidant compounds from Asparagus racemosus Willd. aerial parts	22
Simultaneous determination of nirmatrelvir and ritonavir in human plasma using LC–MS/MS and its pharmacokinetic application in healthy Chinese volunteers	22
Spectrum–effect relationship between GC‐QTOF‐MS fingerprint and antioxidant, anti‐inflammatory activities of Schizonepeta tenuifolia essential oil	21
Application of experimental design in HPLC method optimization and robustness for the simultaneous determination of canagliflozin, empagliflozin, linagliptin, and metformin in tablet	20
A survey of polar stationary phases for hydrophilic interaction chromatography and recent progress in understanding retention and selectivity	20
A simple and rapid HPLC method for determination of parabens and their degradation products in pharmaceutical dosage forms	20
Stability‐indicating reversed‐phase‐HPLC method development and validation for sacubitril/valsartan complex in the presence of impurities and degradation products: Robustness by quality‐by‐design appr	19
Cutting‐edge LC–MS/MS applications in clinical mass spectrometry: Focusing on analysis of drugs and metabolites	18
A gadolinium‐based magnetic ionic liquid for supramolecular dispersive liquid–liquid microextraction followed by HPLC/UV for the determination of favipiravir in human plasma	18
Rapid simultaneous determination of gut microbial phenylalanine, tyrosine, and tryptophan metabolites in rat serum, urine, and faeces using LC–MS/MS and its application to a type 2 diabetes mellitus s	18
Degradation pathways and impurity profiling of the anticancer drug apalutamide by HPLC and LC–MS/MS and separation of impurities using Design of Experiments	17
Rhubarb anthraquinone glycosides protect against cerebral ischemia‐reperfusion injury in rats by regulating brain–gut neurotransmitters	16
Nanofluid of magnetic‐activated charcoal and hydrophobic deep eutectic solvent: Application in dispersive magnetic solid‐phase extraction for the determination and preconcentration of warfarin in biol	16
Simultaneous pharmacokinetic assessment of phytopharmaceuticals in fenugreek extract using LC–MS/MS in Sprague–Dawley rats	16
Impurity profiling and stability‐indicating method development and validation for the estimation of assay and degradation impurities of midostaurin in softgel capsules using HPLC and LC–MS	16

Comparison of chemical constituents of Bupleurum marginatum var. stenophyllum and Bupleurum chinense DC. using UHPLC–Q‐TOF–MS based on a metabonomics approach	16
A sensitive and high‐throughput quantitative liquid chromatography high‐resolution mass spectrometry method for therapeutic drug monitoring of 10 β‐lactam antibiotics, linezolid and two β	15
Method development for determination of imatinib and its major metabolite, N‐desmethyl imatinib, in biological and environmental samples by SA–SHS–LPME and HPLC	15
Nano‐LC: An updated review	14
Development and validation of novel RP‐HPLC method for midostaurin determination using analytical quality by design approach from regulatory perspective and determination of major degradation compound	14
Development of an HPLC–MS method for the determination of four terpene trilactones in Ginkgo biloba leaf extract via quality by design	14
A QbD‐led simple and sensitive RP‐UHPLC method for simultaneous determination of moxifloxacin, voriconazole, and pirfenidone: An application to pharmaceutical analysis	14
Levels of residues and dietary risk assessment of the fungicides myclobutanil, penconazole, tebuconazole, and triadimenol in squash	14
Comparative analysis of chemical constituents by HPLC–ESI–MSⁿ and antioxidant activities of Dendrobium huoshanense and Dendrobium officinale	14
High‐throughput liquid chromatography/electrospray ionization–tandem mass spectrometry method using in‐source collision‐induced dissociation for simultaneous quantification of imatinib, dasatinib, bos	13
Metabolite profiling of IMID‐2, a novel anticancer molecule of piperazine derivative: In silico prediction, in vitro and in vivo metabolite characterization using UPLC–QTOF–MS/MS	13
Development and validation of LC–MS method for the determination of heptaethylene glycol monomethyl ether in benzonatate bulk drugs	13
Risk assessment, development and validation of a GC‐ECD‐based method for the quantification of cypermethrin from green pea	13
A simple isocratic LC method for quantification of trace‐level inorganic degradation impurities (ferricyanide, ferrocyanide, nitrite, and nitrate) in sodium nitroprusside injection and robustness by q	13
Simultaneous determination of cellular adenosine nucleotides, malondialdehyde, and uric acid using HPLC	13
Dissipation and gas chromatographic method for the determination of profenofos residues in/on green pea and cucumber	12
Quality by design‐based development and validation of an HPLC method for simultaneous estimation of pregabalin and piperine in dual drug‐loaded liposomes	12
Application of QbD based approach in development and validation of RP‐HPLC method for simultaneous estimation of methotrexate and baicalin in dual‐drug‐loaded liposomes	12
Quantification of eucalyptol (1,8‐cineole) in rat serum by gas chromatography–mass/mass spectrometry and its application to a rat pharmacokinetic study	12
Stability‐indicating method development and validation for quantitative estimation of assay and organic impurities of antiviral drug baloxavir marboxil in drug substance and pharmaceutical dosage form	12
Simultaneous determination of six antibiotics in human serum by high‐performance liquid chromatography with UV detection	12
Mass spectrometry imaging technology in metabolomics: A systematic review	11
Capillary electrophoresis‐based methodology for screening of oligonucleotide aptamers	11
Development and validation of an HPLC–MS/MS method to simultaneously quantify alectinib, crizotinib, erlotinib, gefitinib and osimertinib in human plasma samples, using one assay run	11
Development and validation of liquid chromatography–tandem mass spectrometry method for the estimation of a potential genotoxic impurity 2‐(2‐chloroethoxy)ethanol in hydroxyzine	11
Pharmacokinetic–pharmacodynamic modeling analysis and anti‐inflammatory effect of Wangbi capsule in the treatment of adjuvant‐induced arthritis	11
Validated HPLC‐MS/MS method for quantitation of AMG 510, a KRAS G12C inhibitor, in mouse plasma and its application to a pharmacokinetic study in mice	11
A review of chromatographic methods for bioactive tryptophan metabolites, kynurenine, kynurenic acid, quinolinic acid, and others, in biological fluids	10
Retention behaviour of analytes in reversed‐phase high‐performance liquid chromatography—A review	10
Comparative pharmacokinetic and bioavailability study of lobetyolin in rats after administration of lobetyolin and Codonopsis pilosula extract by ultra‐performance LC–tandem mass spe	10
Rapid determination of acyclovir, its main metabolite 9‐carboxymethoxymethylguanine, ganciclovir, and penciclovir in human serum using LC–MS/MS	10
Optimization of extraction process and the antioxidant activity spectrum–effect relationship of Angelica dahurica	10
Unique liquid chromatography technique for the determination of mirabegron in the presence of polymers; robustness by Design Expert in the light of Quality by Design	10
Development, method validation and simultaneous quantification of eleven bioactive natural products from high‐altitude medicinal plant by high‐performance liquid chromatography	10
Determination of ceftazidime in plasma by RP‐HPLC and ultraviolet detection	10
A novel method for investigating the mechanism of the anti‐rheumatoid arthritis activity of Angelicae pubescentis radix by integrating UHPLC–QTOF/MS and network pharmacology	10
Favipiravir (SARS‐CoV‐2) degradation impurities: Identification and route of degradation mechanism in the finished solid dosage form using LC/LC–MS method	10
A novel UPLC–MS/MS method for simultaneous quantification of trigonelline, 4‐hydroxyisoleucine, and diosgenin from Trigonella foenum‐graecum extract: Application to pharmacokinetic s	10
Screening of hepatotoxic compounds in Psoralea corylifolia L., a traditional Chinese herbal and dietary supplement, using high‐resolution mass spectrometry and high‐content imaging	10
Simultaneous determination of skimmin, apiosylskimmin, 7‐hydroxycoumarin and 7‐hydroxycoumarin glucuronide in rat plasma by liquid chromatography–Orbitrap mass spectrometry and its application to phar	10
Stability‐indicating ultra performance liquid chromatography method development and validation for simultaneous estimation of metformin, linagliptin, and empagliflozin in bulk and pharmaceutical dosag	10
Development of a simultaneous analytical method for clozapine and its metabolites in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry with linear range adjuste	10
Development of a Pteris vittata L. compound database by widely targeted metabolomics profiling	10
Dissipation kinetics and dietary risk assessment of spiromesifen on major summer vegetables using good agricultural practices	9
Stability‐indicating HPLC method development and validation for simultaneous estimation of metformin, dapagliflozin, and saxagliptin in bulk drug and pharmaceutical dosage form	9
Evaluation of green and efficient deep eutectic solvents as media for extracting alkaloids from lotus leaf	9
Identification of cattle poisoning by Bifenthrin via earwax analysis by HS/GC–MS	9
Development and validation of a liquid chromatography–tandem mass spectrometry method for the simultaneous analysis of androgens, estrogens, glucocorticoids and progestagens in human serum	9
Rapid and sensitive HPLC–MS/MS method for the quantification of dopamine, GABA, serotonin, glutamine and glutamate in rat brain regions after exposure to tobacco cigarettes	9
Intranasal administration of perillyl alcohol–loaded nanoemulsion and pharmacokinetic study of its metabolite perillic acid in plasma and brain of rats using ultra‐performance liquid chromatography/ta	9

Determination of amlodipine, indapamide and perindopril in human plasma by a novel LC–MS/MS method: Application to a bioequivalence study	9
The related mechanism of complete Freund's adjuvant‐induced chronic inflammation pain based on metabolomics analysis	9
Validated HPLC‐UV method for simultaneous quantification of phosphatidylinositol 3‐kinase inhibitors, copanlisib, duvelisib and idelalisib, in rat plasma: Application to a pharmacokinetic study in rat	9
Deep eutectic solvent as the acceptor phase in three‐phase hollow fiber liquid‐phase microextraction for the determination of pyrethroid insecticides from environmental water samples prior to HPLC	9
Rapid determination of rosmarinic acid and its two bioactive metabolites in the plasma of rats by LC–MS/MS and application to a pharmacokinetics study	9
Comparative pharmacokinetics study of six effective components between two dosage forms of Qixue–Shuangbu Prescription in rats by UPLC–MS/MS	9
Exploring the Q‐markers of Angelica sinensis (Oliv.) Diels of anti‐platelet aggregation activity based on spectrum–effect relationships	9
LC–MS‐based plasma metabolomics study of the intervention effect of different polar parts of hawthorn on gastrointestinal motility disorder rats	9
Derivatization‐based quadruplex LC/ESI–MS/MS method for high throughput quantification of serum dehydroepiandrosterone sulfate	8
A robust, accurate, sensitive LC–MS/MS method to measure indoxyl sulfate, validated for plasma and kidney cells	8
An effective and stability‐indicating method development and optimization utilizing the Box–Behnken design for the simultaneous determination of acetaminophen, caffeine, and aspirin in tablet formulat	8
What is necessary for next‐generation atmospheric environmental standards? Recent research trends for PM_2.5‐bound polycyclic aromatic hydrocarbons and their derivatives	8
An LC–ESI–MS/MS assay for the therapeutic drug monitoring of 15 antiseizure medications in plasma of children with epilepsy	8
Acoustic ejection mass spectrometry: Development, applications, and future perspective	8
Comparative investigation of raw and processed products of Gardeniae Fructus and Gardenia jasminoides var. radicans using HPLC coupled with chemometric methods	8
Detection of catecholamine metabolites in urine based on ultra‐high‐performance liquid chromatography–tandem mass spectrometry	8
Measurement of 6‐cyanodopamine, 6‐nitrodopa, 6‐nitrodopamine and 6‐nitroadrenaline by LC–MS/MS in Krebs–Henseleit solution. Assessment of basal release from rabbit isolated right atrium and ventricles	8
Dried blood spots for doping controls—Development of a comprehensive initial testing procedure with fully automated sample preparation	8
Fluorimetric determination of the enantiomers of vigabatrin, an antiepileptic drug, by reversed‐phase HPLC with a novel diastereomer derivatization reagent	8
A rapid LC–MS/MS method for simultaneous determination of berberine and irbesartan in rat plasma: Application to the drug–drug pharmacokinetic interaction study after oral administration in rats	8
Stability‐indicating liquid chromatography method development for assay and impurity profiling of amitriptyline hydrochloride in tablet dosage form and forced degradation study	8
Pharmacokinetic studies of ginsenosides Rk1 and Rg5 in rats by UFLC–MS/MS	8
Hepatotoxicity and nephrotoxicity assessment on ethanol extract of Fructus Psoraleae in Sprague Dawley rats using a UPLC–Q‐TOF–MS analysis of serum metabolomics	8
Trace‐level analysis of polychlorinated biphenyls, organochlorine pesticides and polycyclic aromatic hydrocarbons in human plasma or serum by dispersive liquid–liquid microextraction and gas chromatog	8
Evaluation of the effect of Dahuang–Mudan decoction on TNBS‐induced colitis using UPLC–QTOF/MS‐based metabolomic analysis	8
Proteomics and metabolomics analyses reveal the full spectrum of inflammatory and lipid metabolic abnormalities in dyslipidemia	8
Application of QbD‐based approach to the development and validation of an RP‐HPLC method for simultaneous estimation of pregabalin and naringin in dual‐drug loaded liposomes	8
Development and validation of LC–QTOF–MS/MS method for the identification and determination of low levels of a genotoxic impurity, 4,6‐dichloro‐5‐nitro‐2‐(propylthio)pyrimidine in ticagrelor API	8
Greenness profile assessment of selective liquid chromatographic methods for determination of a quaternary antimigraine combination along with three of their related official impurities	7
A validated stability‐indicating reversed‐phase‐HPLC method for dipyridamole in the presence of degradation products and its process‐related impurities in pharmaceutical dosage forms	7
Simultaneous analysis of drugs administered to lung‐transplanted patients using liquid chromatography–tandem mass spectrometry for therapeutic drug monitoring	7
Comparison of production of bioactive components in Zanthoxylum nitidum taproots from different regions in southern China	7
Fundamental to achieving fast separations with high efficiency: A review of chromatography with superficially porous particles	7
Evaluation of alkylamines and stationary phases to improve LC–MS of oligonucleotides	7
Review of HPLC–MS methods for the analysis of nicotine and its active metabolite cotinine in various biological matrices	7
Rapid screening of α‐glucosidase inhibitors in Hypericum perforatum L. using bio‐affinity chromatography coupled with UPLC/MS	7
US FDA–validated TLC method with four greenness assessment evaluations for simultaneous determination of prednisolone and esomeprazole in spiked human plasma	7
Simultaneous quantification of cyclosporin, tacrolimus, sirolimus and everolimus in whole blood by UHPLC–MS/MS for therapeutic drug monitoring	7
Simultaneous determination of serum homocysteine, cysteine, and methionine in patients with schizophrenia by liquid chromatography–tandem mass spectrometry	7
Analysis of chemical variations between raw and wine‐processed Ligustri Lucidi Fructus by ultra‐high‐performance liquid chromatography–Q‐Exactive Orbitrap/MS combined with multivariate statistical ana	7
Stability‐indicating liquid chromatography method development and validation for impurity profiling of montelukast sodium in bulk drug and tablet dosage form	7
Development and validation of an innovative UPLC method to quantify lacosamide, oxcarbazepine, and lamotrigine in the serum of children with epilepsy in China	7
Development and validation of an LC–MS/MS method for relevant drugs in epilepsy patients using dried blood spots	7
Enhancing effect of borneol on pharmacokinetics of ginsenoside Rb₁, ginsenoside Rg₁, and notoginsenoside R₁ in healthy volunteers after oral administration of compound	7
Pharmacokinetic study of three different formulations of l‐tetrahydropalmatine in brain tissues of rats	7
Determination of linagliptin and empagliflozin by UPLC and HPTLC techniques aided by lean six sigma approach	7
Quantification of field‐incurred residues of cyantraniliprole and IN‐J9Z38 in cabbage/soil using QuEChERS/HPLC‐PDA and dietary risk assessment	7
LC–MS/MS quantification of levetiracetam, lamotrigine and 10‐hydroxycarbazepine in TDM of epileptic patients	7
QbD‐based stability‐indicating liquid chromatography (RP‐HPLC) method for the determination of flurbiprofen in cataplasm	7
Inhibition of human UDP‐glucuronosyltransferase enzyme by Dabrafenib: Implications for drug–drug interactions	7
Simultaneous determination of asarinin, β‐eudesmol, and wogonin in rats using ultraperformance liquid chromatography–tandem mass spectrometry and its application to pharmacokinetic studies following a	6
A strategy to explore the quality markers of Ziziphi Spinosae semen by combining metabolic in vivo study with network pharmacology	6
A rapid and sensitive LC–MS/MS method for the determination of vanillic acid in rat plasma with application to pharmacokinetic study	6
A new method for detecting Na⁺, K⁺‐ATPase activity by ICP–MS: Quantitative analysis on the inhibitory effect of rhein on Na⁺, K⁺‐ATPase activity by ICP–MS i	6
Development and validation of an HPLC–MS/MS method to simultaneously quantify brigatinib, lorlatinib, pralsetinib and selpercatinib in human K2‐EDTA plasma	6
Extraction and pre‐concentration of parabens in liquid pharmaceutical samples by dispersive liquid–liquid microextraction based on deep eutectic solvents	6
Mechanisms exploration of terrestrosin D on pulmonary fibrosis based on plasma metabolomics and network pharmacology	6
Development of an ultra‐high‐performance liquid chromatography–tandem mass spectrometry method for the simultaneous determination of crassicauline A, fuziline, karacoline, and songorine in rat plasma	6
Using a stable isotope‐labeled internal standard for liquid chromatography–tandem mass spectrometry quantitation of meloxicam in human plasma	6
Plasma amino acid metabolomic pattern in heart failure patients with either preserved or reduced ejection fraction: The relation to established risk variables and prognosis	6
Integrative metabolic profile of myelodysplastic syndrome based on UHPLC–MS	6
Characteristic profiling of Aconiti Lateralis Radix for distinguishing it from compatible herbal pair using UPLC–Q‐TOF–MS coupled with chemometrics	6
Dissipation pattern and dietary risk assessment of some commonly used insecticides on tomato (Solanum lycopersicum L.)	6
Combining network pharmacology with chromatographic fingerprinting and multicomponent quantitative analysis for the quality evaluation of Astragali Radix	6
Integration of UPLC–QE–MS/MS and network pharmacology to investigate the active components and action mechanisms of tea cake extract for treating cough	6
Metabolomics study of cerebrospinal fluid from diabetic rats with cognitive impairment simultaneously treated with Panax quinquefolius and Acorus gramineus	6
Sensitive, wide‐range and high‐throughput quantification of cyclosporine in whole blood using ultra‐performance liquid chromatography coupled to tandem mass spectrometry and comparison with an antibod	6
A UPLC–MS/MS method for determination of endogenous l‐carnitine and acetyl‐l‐carnitine in serum of patients with depression	6
Functionalized cryogel monoliths for fast and selective separation of nucleic acids directly from crude lysate	6
Simultaneous determination of pinoxaden, cloquintocet‐mexyl, clodinafop‐propargyl ester and its major metabolite in barley products and soil using QuEChERS modified with multi‐walled carbon nanotubes	6
Comprehensive insights into the formation of metabolites of the ghrelin mimetics capromorelin, macimorelin and tabimorelin as potential markers for doping control purposes	6
Electrophoretic deposition of polyaniline nanofibers on a stainless steel wire as an adsorbent for determination of tamoxifen by SPME/GC–FID in urine samples	6
High‐throughput UPLC‐Q‐TOF‐MS/MS coupled with multivariable data processing approach for the rapid screening and characterization of chemical constituents and potential bioactive compounds from Danggu	6
Dissipation kinetics, risk assessment, and waiting period of spiromesifen on chili fruits using gas chromatography–electron capture detector	6
Simultaneous determination of meropenem and imipenem in rat plasma by LC–MS/MS and its application to a pharmacokinetic study	6
Identification of the metabolites of n‐butylidenephthalide in rat and human liver microsomes by liquid chromatography–high‐resolution mass spectrometry	6
Systematically identifying the anti‐inflammatory constituents of Cimicifuga dahurica by UPLC–Q/TOF–MS combined with network pharmacology analysis	6
LC‐HRMS‐based targeted metabolomics for high‐throughput and quantitative analysis of 21 growth inhibition‐related metabolites in Chinese hamster ovary cell fed‐batch cultures	6
Metabolomics study of the effect of Danggui Buxue Tang on rats with chronic fatigue syndrome	6
Highly sensitive quantification of pemetrexed in human plasma using UPLC‐MS/MS to support microdosing studies	5

Studies on effect of Tongfengxiaofang in HUM model mice using a UPLC–ESI–Q‐TOF/MS metabolomic approach	5
Sensitive LC–MS/MS method for quantification of rivaroxaban in plasma: Application to pharmacokinetic studies	5
LC–MS/MS method for determination of seneciphylline and its metabolite, seneciphylline N‐oxide in rat plasma, and its application to a rat pharmacokinetic study	5
Development and application of a novel LC–MS/MS method for human plasma concentration monitoring of perampanel in pediatric epilepsy patients	5
Development and validation of an LC–MS/MS method for the quantification of artificial sweeteners in human matrices	5
Study on the material basis of Dahuang Zhechong pill of anti‐hepatoma effect by promoting vascular normalization	5
A simple and efficient sequential electrokinetic and hydrodynamic injections in micellar electrokinetic chromatography method for quantification of anticancer drug 5‐fluorouracil and its metabolite in	5
Absorption characteristics of ilexgenin A and ilexsaponin B1 in human umbilical vein endothelial cells after administration of the total triterpenoid saponins from Ilex pubescens	5
Screening of superior anti‐osteoporotic flavonoids from Epimedii Folium with dual effects of reversing iron overload and promoting osteogenesis	5
Pharmacokinetic comparisons of six steroid saponins in rat plasma following oral administration of crude and stir‐fried Fructus Tribuli extracts by UHPLC–MS/MS	5
In silico–in vitro estimation of lipophilicity and permeability association for succinimide derivatives using chromatographic anisotropic systems and parallel artificial membrane permeability a	5
Untargeted metabolomics reveals the mechanism of quercetin enhancing the bioavailability of ticagrelor	5
Reversed‐phase‐HPLC enantioseparation and control of enantiomeric purity of duloxetine using a new chiral reagent and recovery of enantiomers	5
Simultaneous quantitation of serum caffeine and its metabolites by ultra‐high‐performance liquid chromatography–tandem mass spectrometry for CYP1A2 activity prediction in premature infants	5
Recent advances in the detection of drugs of abuse by dried blood spots	5
Poly‐pathways metabolomics for high‐yielding cordycepin of Cordyceps militaris	5
Development and evaluation of a novelty single‐step cleanup followed by HPLC‐QTRAP‐MS/MS for rapid analysis of tricaine, tetracaine, and bupivacaine in fish samples	5
In vitro wound healing properties, antioxidant activities, HPLC–ESI–MS/MS profile and phytoconstituents of the stem aqueous methanolic extract of Dracaena reflexa Lam	5
HPLC–ESI/MS profiling, phytoconstituent isolation and evaluation of renal function, oxidative stress and inflammation in gentamicin‐induced nephrotoxicity in rats of Ficus spragueana Mildbr. &a	5
Stability‐indicating HPLC method development and validation of rivaroxaban impurities and identification of forced degradation products using LC–MS/MS	5
Development and validation of gas chromatography with electron capture detection method using QuEChERS for pesticide residue determination in cucumber	5
Widely targeted metabolomics analysis of different parts of kudzu	5
A membrane solid‐phase extraction method based on MIL‐53‐mixed‐matrix membrane for the determination of estrogens and parabens: Polyvinylidene difluoride membrane versus polystyrene‐block‐polybutadien	5
Dose identification of triamcinolone acetonide for noninvasive pre‐corneal administration in the treatment of posterior uveitis using a rapid, sensitive HPLC method with photodiode‐array detector	5
Establishment and validation of an SIL‐IS LC–MS/MS method for the determination of ibuprofen in human plasma and its pharmacokinetic study	5
Simultaneous quantification of losartan potassium and its active metabolite, EXP3174, in rabbit plasma by validated HPLC–PDA	5
Simultaneous determination of serum tryptophan metabolites in an older Chinese population	5
Comparative analysis of excretion of six major compounds of Polygonum orientale L. extract in urine, feces and bile under physiological and myocardial ischemia conditions in rats usi	5
Metabonomics analysis of semen euphorbiae and semen Euphorbiae Pulveratum using UPLC–Q‐TOF/MS	5
Integrative proteomics and metabolomics approach to elucidate the antimicrobial effect of simvastatin on Escherichia coli	5
Development of effervescence‐assisted switchable polarity solvent homogeneous liquid‐phase microextraction for the determination of permethrin and deltamethrin in water samples prior to gas chromatogr	5
Orbitrap‐MS‐based untargeted metabolomics study on the therapeutic effect of colchicine on myocardial infarction	5
Fully validated UPLC–MS/MS method for quantifying Favipiravir in human plasma boosted lean six sigma: An application for a bioequivalence study	5
Development and validation of apalutamide‐related substances method in solid dosage forms using HPLC	5
A UPLC–MS/MS method for simultaneous determination of nine antiepileptic drugs in human plasma and its application in TDM	5
Pharmacokinetics and tissue distribution study of obtusifolin in rats by liquid chromatography–tandem mass spectrometry	5
Exploring lipid biomarkers of coronary heart disease for elucidating the biological effects of gelanxinning capsule by lipidomics method based on LC–MS	5
Comprehensive study of allergenic tree species: Palynological insights enhanced by HPLC and GC–MS profiling	5
Chemometric analysis of active compounds and antioxidant and α‐glucosidase inhibitory activities for the quality evaluation of licorice from different origins	5
Pharmacokinetic characteristics of hydroxysafflor yellow A in normal and diabetic cardiomyopathy mice	5
Polycyclic aromatic hydrocarbons residues and the carcinogenic risk assessment to pregnant women in Nantong, China using QuEChERS method and HPLC—A pilot case study	5
An observation study of urinary biomarker exploratory in Alzheimer's disease using high‐resolution mass spectrometry	5
Application of supercritical fluid chromatography for separation and quantitation of 15 co‐formulated binary anti‐hypertensive medications using a single elution protocol	5
Development and validation of HPLC method for simultaneous quantification of alpha‐tocopherol (free or encapsulated) and cholesterol in semen cryopreservation media	5
Improved HPLC method for the determination of ribavirin concentration in red blood cells and its application in patients with COVID‐19	5
Changes in the essential oil content and composition of Salvia limbata C.A. Mey at different growth stages and altitudes	5
Stability evaluation of morphine, hydromorphone, metamizole and esketamine containing analgesic mixtures applied for patient‐controlled analgesia in hospice and palliative care	5
Adipo‐specific chemerin knockout alters the metabolomic profile of adipose tissue under normal and high‐fat diet conditions: Application of an untargeted liquid chromatography–tandem mass spectrometry	5
Characterization of the metabolism of aloin A/B and aloesin in rats using ultra‐high performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry	5
Quantitation of plasma angiotensin II in healthy Chinese subjects by a validated liquid chromatography tandem mass spectrometry method	5
Explore the effects of Shidan granules on chronic atrophic gastritis using LC–MS based plasma metabolomics study	5
Investigation of the impact of grapefruit juice, pomegranate juice and tomato juice on pharmacokinetics of brexpiprazole in rats using UHPLC–QTOF–MS	5
Application of microcrystalline cellulose as an efficient and cheap sorbent for the extraction of metoprolol from plasma and wastewater before HPLC–MS/MS determination	5
Characterization of molecularly imprinted polymers for the extraction of tobacco alkaloids and their metabolites in human urine	5
Pharmacokinetic and metabolic profiling studies of osmundacetone in rats by UPLC–MS/MS and UPLC–QE–Orbitrap–HRMS	5
Mitochondria metabonomics of Huangqi Jianzhong Tang against chronic atrophic gastritis	4
A stability‐indicating, reversed‐phase HPLC method for quantification of assay and organic impurities in doxycycline hyclate bulk and parenteral dosage forms	4
Investigating the in vivo effect of Tribulus terrestris extract in middle cerebral artery occlusion rats using LC–MS‐based metabolomics combined with molecular docking	4
The pharmacokinetic characteristics and excretion studies of fucosterol from Sargasssum fusiforme in rats	4
Rapid determination of 20 bile acids in human serum by ultra performance liquid chromatography–tandem mass spectrometry	4
Application of a Quality by Design‐based approach in development and validation of an RP‐HPLC method for simultaneous estimation of methotrexate and mangiferin in dual drug‐loaded liposomes	4
A review of extraction methods and analytical techniques for styrene and its metabolites in biological matrices	4
Inhibitory effects of astilbin, neoastilbin and isoastilbin on human cytochrome CYP3A4 and 2D6 activities	4
Isolation and characterization of Newcastle disease virus from biological fluids using column chromatography	4
Identification and validation of potential genotoxic impurities, 1,3‐dichloro‐2‐propanol, and 2,3‐dichloro‐1‐propanol, at subtle levels in a bile acid sequestrant, colesevelam hydrochloride, using hyp	4
A simple HPLC assay for determining eltrombopag concentration in human serum	4
A novel and sensitive method for determination of amisulpride in human plasma by two‐dimensional liquid chromatography	4
Chemical‐activity‐based quality marker screening strategy for Viscum articulatum	4
Selective and reliable determination of obacunone in rat plasma using solid‐phase extraction by liquid chromatography tandem mass spectrometry: Application to a pharmacokinetic study	4
Hepatic effect of subacute Fe₂O₃ nanoparticles exposure in Sprague–Dawley rats by LC–MS/MS based lipidomics	4
Comparative pharmacokinetics, intestinal absorption and urinary excretion of six alkaloids from herb pair Phellodendri Chinensis cortex–Atractylodis Rhizoma	4
Liquid chromatography–tandem mass spectrometry method for simultaneous quantification of neurotransmitters in rat brain tissue exposed to 4′‐fluoro‐α‐PHP	4
Determination of the concentration of gilteritinib in human plasma using HPLC	4
Identification of the metabolites of tofacitinib in liver microsomes by liquid chromatography combined with high resolution mass spectrometry	4
Determination, residue analysis, dietary risk assessment, and processing of flupyradifurone and its metabolites in pepper under field conditions using LC–MS/MS	4
Development of a joint derivatization protocol for the unequivocal identification of the monosaccharide composition in four dendrobium polysaccharides and free monosaccharide by GC–MS	4
Determination of nootkatone in rat plasma by LC–tandem mass spectrometry and its application in a pharmacokinetic study	4
Perspectives on updates, clarifications and controversies in chromatographic assay guidance for bioanalytical method validation from major regulatory agencies and organizations	4
Metabolomic comparison between natural Huaier and artificial cultured Huaier	4
Evaluation of the effects of notoginseng total saponins (NS), safflower total flavonoids (SF), and the combination of NS and SF (CNS) on the activities of cytochrome P450 enzymes using a cocktail meth	4
Screening of differential components of Gegenqinlian decoction and their comparative pharmacokinetics in normal and pyrexia rats using UHPLC‐FT‐ICR‐MS and UHPLC–MS/MS	4
Determination of fingerprints contents of different extracts and parts of six endemic Salvia taxa by GC–MS: Source species for valuable compounds with drug or drug potential	4
Integrated UPLC–Q‐TOF–MS and network pharmacology approach‐driven quality marker discovery of Danggui Shaoyao San for primary dysmenorrhea	4
Developing an analytical method by HPLC for simultaneous quantification of methylene blue and metformin applied to in vitro skin permeation and retention studies	4
The protective effect of electroacupuncture on the renal cortex of SHRs: A metabonomic analysis	4
Profiling of widely targeted metabolomics for the identification of chemical composition in epidermis, xylem and pith of Gleditsiae Spina	4
Spectrum–effect relationship between high‐performance thin‐layer chromatography data and xanthine oxidase inhibitory activity of celery seed extract	4
Comparative pharmacokinetics of four major flavonoids in normal and chronic gastritis rats after oral administration of different combinations of Banxia Xiexin decoction	4
Identification of carbonylated proteins from monocytic cells under diabetes‐induced stress conditions	4
Isolation and identification in human blood serum of the proteins possessing the ability to bind with 48 kDa form of unconventional myosin 1c and their possible diagnostic and prognostic value	4
A reversed‐phase‐high performance liquid chromatography method for simultaneous determination of paracetamol, caffeine, drotaverine HCl and their related impurities with dissolution profiling of their	4
Urinary phenylethylamine metabolites as potential markers for sports drug testing purposes	4
Determination of progesterone (steroid drug) in the semi‐solid dosage form (vaginal gel) using a stability‐indicating method by RP‐HPLC/PDA detector	4
Preparation, characterization and wound‐healing effect of PEGylated nanoliposomes loaded with oleuropein	4
Pharmacokinetics, bioavailability and metabolism of CC‐92480 in rat by liquid chromatography combined with electrospray ionization tandem mass spectrometry	4