OOIR: Observatory of International Research

Papers

(The median citation count of Mutagenesis is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The BlueScreen HC assay to predict the genotoxic potential of fragrance materials	208
A comparative analysis of the mutagenicity of platinum-containing chemotherapeutic agents reveals direct and indirect mutagenic mechanisms	23
Collection and storage of human white blood cells for analysis of DNA damage and repair activity using the comet assay in molecular epidemiology studies	21
Organoids for toxicology and genetic toxicology: applications with drugs and prospects for environmental carcinogenesis	19
Validation of the 3D reconstructed human skin micronucleus (RSMN) assay: an animal-free alternative for following-up positive results from standardin vitrogenotoxicity assays	19
NEK1 deficiency affects mitochondrial functions and the transcriptome of key DNA repair pathways	16
Genetic damage in lymphocytes of lung cancer patients is correlated to the composition of the respiratory tract microbiome	15
The role of human umbilical cord mesenchymal stem cells-derived exosomal microRNA-431-5p in survival and prognosis of colorectal cancer patients	15
The in vitro ToxTracker and Aneugen Clastogen Evaluation extension assay as a tool in the assessment of relative genotoxic potential of e-liquids and their aerosols	14
Telomere length in peripheral blood lymphocytes related to genetic variation in telomerase, prognosis and clinicopathological features in breast cancer patients	13
Methylglyoxal induces chromosomal instability and mitotic dysfunction in lymphocytes	10
Empirical comparison of genotoxic potency estimations: the in vitro DNA-damage ToxTracker endpoints versus the in vivo micronucleus assay	10
Cobalt oxide (Co3O4) nanoparticles induced genotoxicity in Chinese hamster lung fibroblast (V79) cells through modulation of reactive oxygen species	9
Air pollution in Sarajevo, Bosnia and Herzegovina, assessed by plant comet assay	9
Cytoprotective and genoprotective effects of taxifolin against oxidative damage in HTR-8/SVneo human trophoblast cells	8
In vitro and integrated in vivo strategies to reduce animal use in genotoxicity testing	8
Visual comet scoring revisited: a guide to scoring comet assay slides and obtaining reliable results	8
Biomarkers of DNA damage response improve in vitro micronucleus assays by revealing genotoxic mode of action and reducing the occurrence of irrelevant positive results	8
Probiotic bacteria isolated from fermented meat displays high antioxidant and anti-inflammatory potential	8
DNA damage in peripheral blood lymphocytes of severely ill COVID-19 patients in relation to inflammatory markers and parameters of hemostasis	7
The suitability of micronuclei as markers of relative biological effect	7
The hen’s egg test for micronucleus induction (HET-MN): validation data set	7
Epigenetic effect of the mycotoxin fumonisin B1 on DNA methylation	7
Do RNA vaccines obviate the need for genotoxicity studies?	7
Multi-endpoint analysis of cadmium chloride-induced genotoxicity shows role for reactive oxygen species and p53 activation in DNA damage induction, cell cycle irregularities, and cell size aberrations	6

Folic acid deficiency increases sensitivity to DNA damage by glucose and methylglyoxal	6
Optimizing machine-learning models for mutagenicity prediction through better feature selection	6
Action-at-a-distance mutations at 5′-GpA-3′ sites induced by oxidised guanine in WRN-knockdown cells	6
Single and combined potential of polystyrene microparticles and fluoranthene in the induction of DNA damage in haemocytes of Mediterranean mussel (Mytilus galloprovincialis)	6
Divergent molecular profile of PIK3CA gene in arsenic-associated bladder carcinoma	6
Hawk-Seq™ differentiates between various mutations in Salmonella typhimurium TA100 strain caused by exposure to Ames test-positive mutagens	6
Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected	6
Manool, a diterpene from Salvia officinalis, exerts preventive effects on chromosomal damage and preneoplastic lesions	6
Long-term cryopreservation of potassium bromate positive assay controls for measurement of oxidatively damaged DNA by the Fpg-modified comet assay: results from the hCOMET ring trial	6
Genetic variations in 3′UTRs ofSMUG1andNEIL2genes modulate breast cancer risk, survival and therapy response	6
In vitro mutagenicity of selected environmental carcinogens and their metabolites in MutaMouse FE1 lung epithelial cells	5
A pilot biomonitoring study of air pollution in the urban area of Sarajevo, Bosnia and Herzegovina: genotoxicity assessment in buccal cells	5
Mutational landscape of plasma cell-free DNA identifies molecular features associated with therapeutic response in patients with colon cancer. A pilot study	5
Inter-laboratory variation in measurement of DNA damage by the alkaline comet assay in the hCOMET ring trial	5
Assessment of mutations induced by cold atmospheric plasma jet treatment relative to known mutagens in Escherichia coli	5
Folate deficiency enhances the in vitro genotoxicity of bile acids in human colon and liver cells	5
A novel in vitro 3D model of the human bone marrow to bridge the gap between in vitro and in vivo genotoxicity testing	5
Genotoxicity by rapeseed methyl ester and hydrogenated vegetable oil combustion exhaust products in lung epithelial (A549) cells	4
Current status and future challenges of genotoxicity OECD Test Guidelines for nanomaterials: a workshop report	4
The role of Gentiana lutea extracts in reducing UV-induced DNA damage	4
In vitro genotoxicity assessment of French fries from mass catering companies: a preliminary study	4
Validation of the hen’s egg test for micronucleus induction (HET-MN): detailed protocol including scoring atlas, historical control data and statistical analysis	4
DNA damage in leukocytes and serum nitrite concentration are negatively associated in type 1 diabetes	4
Benchmark dose analysis of multiple genotoxicity endpoints in gpt delta mice exposed to aristolochic acid I	4
UCTD and SLE patients show increased levels of oxidative and DNA damage together with an altered kinetics of DSB repair	4
Genome-wide analysis of DNaseI hypersensitivity unveils open chromatin associated with histone H3 modifications after areca nut with lime exposure	3
Measuring blood cell DNA damage using the PIG-A mutation and CBMN assay in pancreatic cancer patients: a pilot study	3
Investigation of genotoxic effect of octyl gallate used as an antioxidant food additive in in vitro test systems	3
Glutathione-related antioxidant defence, DNA damage, and DNA repair in patients suffering from post-COVID conditions	3
Critical review of the publications on the genotoxicology of aluminium salts: 1990–2018	3
Ex vivo explant model of adenoma and colorectal cancer to explore mechanisms of action and patient response to cancer prevention therapies	3
Interspecific differences in oxidative DNA damage after hydrogen peroxide exposure of sea urchin coelomocytes	3
Use of the EpiDermTM 3D reconstructed skin micronucleus assay for fragrance materials	3
In situdetection of the genotoxic potential as one of the lines of evidence in the weight-of-evidence approach—the Joint Danube Survey 4 Case Study	3
Detection of urethane-induced genotoxicity in vitro using metabolically competent human 2D and 3D spheroid culture models	3
Action-at-a-distance mutations induced by 8-oxo-7,8-dihydroguanine are dependent on APOBEC3	2
Trichostatin A mitigates radiation-induced teratogenesis in C57Bl/6 mice	2
The mitochondrial poison carbonyl cyanide 3-chlorophenyl hydrazone (CCCP) induces aneugenic effects in primary human fibroblasts: a possible link between mitochondrial dysfunction and chromosomal loss	2
Comparative analysis of Ag NPs functionalized with olive leaf extract and oleuropein and toxicity in human trophoblast cells and peripheral blood lymphocytes	2
Matrine and Oxymatrine: evaluating the gene mutation potential using in silico tools and the bacterial reverse mutation assay (Ames test)	2
N-Nitrosodimethylamine investigations in Muta™Mouse define point-of-departure values and demonstrate less-than-additive somatic mutant frequency accumulations	2
Impact of mobile phone-specific electromagnetic fields on DNA damage caused by occupationally relevant exposures: results of ex vivo experiments with peripheral blood mononuclear cells from dif	2
Genome instability in peripheral blood lymphocytes of patients with heart failure and reduced ejection fraction	2
Ames test study designs for nitrosamine mutagenicity testing: qualitative and quantitative analysis of key assay parameters	2
Follow-up genotoxicity assessment of Ames-positive/equivocal chemicals using the improved thymidine kinase gene mutation assay in DNA repair-deficient human TK6 cells	2
Impact of experimental design factors on the potency of genotoxicants in in vitro tests	2