Natural Product Reports

Papers
(The median citation count of Natural Product Reports is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
The molecular complexity of terpene biosynthesis in red algae: current state and future perspectives203
Recent advances in the synthesis of insect pheromones: an overview from 2013 to 2022170
Privileged natural product compound classes for anti-inflammatory drug development126
Silybin and its congeners: from traditional medicine to molecular effects125
Biosynthesis, regulation, and engineering of natural products from Lysobacter120
Harnessing microbial co-culture to increase the production of known secondary metabolites101
Estimating the extent of adulteration of the popular herbs black cohosh, echinacea, elder berry, ginkgo, and turmeric – its challenges and limitations100
Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis99
Front cover95
Back cover90
Purine nucleoside antibiotics: recent synthetic advances harnessing chemistry and biology78
The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide78
Inside front cover78
Recent advances in the total synthesis of galantamine, a natural medicine for Alzheimer's disease77
Medicinal plant resin natural products: structural diversity and biological activities74
Streptomyces cell-free systems for natural product discovery and engineering71
Discovery, bioactivity and biosynthesis of fungal piperazines69
Introduction to engineering the biosynthesis of fungal natural products67
Unusually cyclized triterpenoids: occurrence, biosynthesis and chemical synthesis66
Recent advances in the biosynthetic studies of bacterial organoarsenic natural products65
Inside front cover64
Front cover64
Correction: Dearomative logic in natural product total synthesis62
Maleidride biosynthesis – construction of dimeric anhydrides – more than just heads or tails62
Marine indole alkaloid diversity and bioactivity. What do we know and what are we missing?58
Prenylated bacterial natural products: occurrence, chemical diversity, biosynthesis and bioactivity58
Chemoenzymatic approaches to plant natural product inspired compounds55
Toward a unified pipeline for natural product discovery: tools and strategies for NRPS and PKS pathway exploration and engineering55
Marine natural products54
Chemistry, bioactivity, biosynthesis, and total synthesis of stemmadenine alkaloids50
Non-peptide secondary metabolites from poisonous mushrooms: overview of chemistry, bioactivity, and biosynthesis49
Natural nematicidal metabolites and advances in their biocontrol capacity on plant parasitic nematodes48
Front cover47
Contents list47
Enzymatic ester bond formation strategies in fungal macrolide skeletons47
Contents list47
Back cover46
Contents list45
Synthetic-bioinformatic natural product-inspired peptides44
Image to insight: exploring natural products through mass spectrometry imaging44
Subterranean marvels: microbial communities in caves and underground mines and their promise for natural product discovery44
The role ofCaenorhabditis elegansin the discovery of natural products for healthy aging43
Biosynthesis of fungal terpenoids41
Contents list41
Hot off the Press41
Front cover39
Front cover39
Strategies for the synthesis ofStemonaalkaloids: an update38
Advances in the total synthesis of bis- and tris-indole alkaloids containing N-heterocyclic linker moieties37
Enzymatic crosslinking of histidine side chains in peptide natural products37
Terpene synthases and pathways in animals: enzymology and structural evolution in the biosynthesis of volatile infochemicals37
Labelling studies in the biosynthesis of polyketides and non-ribosomal peptides36
Illuminating the dark space of bioactive peptides with mass spectrometry36
Technological developments driving industrial natural product discovery36
[2 + 2]-Cycloaddition-derived cyclobutane natural products: structural diversity, sources, bioactivities, and biomimetic syntheses36
Contents list35
Back cover35
Back cover33
Inside front cover33
Hot off the Press33
Back cover33
Structure-based engineering of α-ketoglutarate dependent oxygenases in fungal meroterpenoid biosynthesis32
Contents list32
Synthesis of rearranged indole diterpenes of the paxilline type32
Back cover32
Chemistry and biosynthesis of bacterial polycyclic xanthone natural products31
Biosynthesis of indole diterpenes: a reconstitution approach in a heterologous host31
Engineering the biosynthesis of fungal nonribosomal peptides30
Advances and challenges in ginseng research from 2011 to 2020: the phytochemistry, quality control, metabolism, and biosynthesis30
Anthrol reductases: discovery, role in biosynthesis and applications in natural product syntheses29
Chemistry, biosynthesis and biology of floral volatiles: roles in pollination and other functions29
Modular polyketide synthase-derived insecticidal agents: from biosynthesis and metabolic engineering to combinatorial biosynthesis for their production29
Recent advances in oxidative phenol coupling for the total synthesis of natural products29
The shikimate pathway: gateway to metabolic diversity29
Natural product-based PROteolysis TArgeting Chimeras (PROTACs)29
Natural products as anthelmintics: safeguarding animal health28
Back cover28
Structural enzymology of iterative type I polyketide synthases: various routes to catalytic programming28
Contents list28
Vallesamidine and schizozygane alkaloids: rearranged monoterpene indole alkaloids and synthetic endeavours27
Connecting metabolome and phenotype: recent advances in functional metabolomics tools for the identification of bioactive natural products27
Production of high molecular-ordered stilbene oligomers for the study of their biological activity: total synthesis, bio-catalyzed synthesis and production by plant systems27
Strategies for total synthesis of bispyrrolidinoindoline alkaloids26
A critical review on the use of DP4+ in the structural elucidation of natural products: the good, the bad and the ugly. A practical guide26
Bacterial cyclophane-containing RiPPs from radical SAM enzymes26
Front cover25
Semi-synthesis in the exploration of opioid-targeting natural products25
Contents list25
Back cover25
Contents list25
Contents list24
Biosynthesis and bioactivities of microbial genotoxin colibactins24
Strategies and tactics for the synthesis of lipid I and II and shortened analogues: functional building blocks of bacterial cell wall biosynthesis24
Recent advances in total synthesis of protoberberine and chiral tetrahydroberberine alkaloids24
The chemical and biological properties of natural resorcylic acid lactones23
The action of phytochemicals in biofilm control23
Therapeutic vulnerabilities of cancer stem cells and effects of natural products23
Analytical methods for the analysis of volatile natural products23
Opportunities and challenges of RiPP-based therapeutics22
Unlocking marine treasures: isolation and mining strategies of natural products from sponge-associated bacteria22
Warfare under the waves: a review of bacteria-derived algaecidal natural products22
Front cover21
Advances, opportunities, and challenges in methods for interrogating the structure activity relationships of natural products21
Egg toxic compounds in the animal kingdom. A comprehensive review21
Contents list21
Contents list21
Contents list20
The development of Burkholderia bacteria as heterologous hosts20
Back cover20
Biosynthesis of fungal polyketides by collaborating and trans-acting enzymes20
Intramolecular cycloaddition of nitrones in total synthesis of natural products20
Back cover20
Recent insights into the biosynthesis and biological activities of the peptide-derived redox cofactor mycofactocin20
40 Years of Natural Product Reports19
Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic19
Challenges and opportunities for cheat therapy in the control of bacterial infections19
Contents list19
The ins and outs of transporters at plasma membrane and tonoplast in plant specialized metabolism19
Correction: Biosynthesis, biological activities, and structure–activity relationships of decalin-containing tetramic acid derivatives isolated from fungi19
Specialized metabolite modifications in Brassicaceae seeds and plants: diversity, functions and related enzymes18
Discovery and development of botanical natural products and their analogues as therapeutics for ovarian cancer18
The bisintercalator family of nonribosomal peptides: structural diversity and biosynthetic mechanism18
Recent advances in the application of the isoxazoline route to aldols in the synthesis of natural products18
Structural insights into the diverse prenylating capabilities of DMATS prenyltransferases17
Back cover17
Volatile organic compounds (VOCs) in terrestrial extreme environments: implications for life detection beyond Earth17
Front cover17
Back cover16
Inside front cover16
Contents list16
Introduction to volatile natural products16
Contents list16
Contents list16
Trends in metabolite discovery from Actinomycetes15
Chemistry and bioactivity of lindenane sesquiterpenoids and their oligomers15
Correction: Structural diversity, bioactivities, and biosynthesis of natural diterpenoid alkaloids15
Embracing the era of antimicrobial peptides with marine organisms14
Anthracyclines: biosynthesis, engineering and clinical applications14
Engineering fungal terpene biosynthesis13
Biosynthesis of pyrroloindoline-containing natural products13
Recent advances in discovery and biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPP)-derived lipopeptides13
Picrotoxane sesquiterpenoids: chemistry, chemo- and bio-syntheses and biological activities13
Back cover12
Advances in the discovery and study of Trichoderma natural products for biological control applications12
Highlights of biosynthetic enzymes and natural products from symbiotic cyanobacteria12
Organic synthesis in the study of terpene-derived oxidation products in the atmosphere12
Back cover12
Recent advances in the discovery of plant-derived antimicrobial natural products to combat antimicrobial resistant pathogens: insights from 2018–202212
Back cover12
Natural products of pentacyclic triterpenoids: from discovery to heterologous biosynthesis12
Cephalotane diterpenoids: structural diversity, biological activity, biosynthetic proposal, and chemical synthesis12
Structural diversity and biological relevance of benzenoid and atypical ansamycins and their congeners11
Comparing total chemical synthesis and total biosynthesis routes to fungal specialized metabolites11
Extraction techniques for bioactive compounds of cannabis11
Chemistry and biology of natural stilbenes: an update11
Accelerating enzyme discovery and engineering with high-throughput screening11
Scaling up for success: from bioactive natural products to new medicines11
Bioactive natural products from Bacteroidetes11
The Kornblum DeLaMare rearrangement in natural product synthesis: 25 years of innovation10
Meroterpenoids? A historical and critical review of this biogenetic determinant10
Chemical diversity of cyanobacterial natural products10
Ribosome-independent peptide biosynthesis: the challenge of a unifying nomenclature10
Finding activity through rigidity: syntheses of natural products containing tricyclic bridgehead carbon centers9
Back cover9
Front cover9
Structure, properties of gossypol and its derivatives—from physiological activities to drug discovery and drug design9
Fe(ii) and 2-oxoglutarate-dependent dioxygenases for natural product synthesis: molecular insights into reaction diversity9
Inside front cover9
Microbial polyketides and their roles in insect virulence: from genomics to biological functions9
Scalemic natural products9
Hot off the Press9
Unpacking policy developments in marine natural product research: a scientist's guide to DSI and BBNJ9
Biosynthesis, total synthesis, and pharmacological activities of aryltetralin-type lignan podophyllotoxin and its derivatives9
The fungal natural product class of the sorbicillinoids: structures, bioactivities, biosynthesis, and synthesis9
Euphorbiaditerpenoids: isolation, structure, bioactivity, biosynthesis, and synthesis (2013–2021)9
Unveiling Amaryllidaceae alkaloids: from biosynthesis to antiviral potential – a review9
S-Adenosylmethionine: more than just a methyl donor8
Bacterial polyynes uncovered: a journey through their bioactive properties, biosynthetic mechanisms, and sustainable production strategies8
Contents list8
Contents list7
Natural ten-membered lactones: sources, structural diversity, biological activity, and intriguing future7
Huperzine alkaloids: forty years of total syntheses7
Strategies for the discovery of potential anticancer agents from plants collected from Southeast Asian tropical rainforests as a case study7
Hot off the Press7
Chemical synthesis in competition with global genome mining and heterologous expression for the preparation of dimeric tryptophan-derived 2,5-dioxopiperazines7
Verticillins: fungal epipolythiodioxopiperazine alkaloids with chemotherapeutic potential7
Engineering modular enzyme assembly: synthetic interface strategies for natural products biosynthesis applications7
Natural products targeting the metabolism of amino acids: from discovery to synthetic development6
Front cover6
Contents list6
Plant-based engineering for production of high-valued natural products6
Integrative omics approaches for biosynthetic pathway discovery in plants6
para-Quinone methides in natural product biosynthesis6
Current status of secondary metabolite pathways linked to their related biosynthetic gene clusters in Aspergillus section Nigri6
The phosphate ester group in secondary metabolites6
Recent advances in the synthesis of ent-kaurane diterpenoids6
Antarctic bacterial natural products: from genomic insights to drug discovery6
Harnessing intercellular signals to engineer the soil microbiome5
The cytochalasans: potent fungal natural products with application from bench to bedside5
Plant peptides – redefining an area of ribosomally synthesized and post-translationally modified peptides5
Dietary substances and their glucuronides: structures, occurrence and biological activity5
Anti-mycobacterial natural products and mechanisms of action5
Back cover5
Discovery, structure revision, synthesis, and application of all known and even unknown securingine alkaloids5
Medium-sized peptides from microbial sources with potential for antibacterial drug development5
Alternative metabolic pathways and strategies to high-titre terpenoid production inEscherichia coli4
Back cover4
Back cover4
Describing the complex chemistry of benthic seawater: from exometabolite sampling strategies to MS-based metabolomics4
Polyamine-containing natural products: structure, bioactivity, and biosynthesis4
Front cover4
Hot off the press4
Back cover4
Controllable skeletal reorganizations in natural product synthesis4
Natural products from plants targeting key enzymes for the future development of antidiabetic agents4
Chemistry and biology of specialized metabolites produced by Actinomadura4
Front cover3
Back cover3
Fruity, sticky, stinky, spicy, bitter, addictive, and deadly: evolutionary signatures of metabolic complexity in the Solanaceae3
Hot off the Press3
Corallopyronin A: antimicrobial discovery to preclinical development3
Back cover3
Contents list3
Regulation of daptomycin biosynthesis in Streptomyces roseosporus: new insights from genomic analysis and synthetic biology to accelerate lipopeptide discovery and commercial production3
On the evolution of coenzyme biosynthesis3
Hot off the Press3
Contents list3
Recent highlights of the total synthesis of cyclic peptide natural products3
Front cover3
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