OOIR: Observatory of International Research

Papers

(The TQCC of Cell Biochemistry and Function is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Ageing and mesenchymal stem cells derived exosomes: Molecular insight and challenges	69
Computational targeting of allosteric site of MEK1 by quinoline‐based molecules	51
Photobiomodulation in diabetic wound healing: A review of red and near‐infrared wavelength applications	36
ATG5: A central autophagy regulator implicated in various human diseases	34
Gene therapy: A promising approach for breast cancer treatment	33
Inhibition of nonstructural protein 15 of SARS‐CoV‐2 by golden spice: A computational insight	33
Phenolic compounds as antidiabetic, anti‐inflammatory, and anticancer agents and improvement of their bioavailability by liposomes	32
Oxidativestress‐Adirect bridge to central nervous system homeostatic dysfunction and Alzheimer's disease	27
Angiogenesis induction in breast cancer: A paracrine paradigm	26
Semaglutide (GLP‐1 receptor agonist) stimulates browning on subcutaneous fat adipocytes and mitigates inflammation and endoplasmic reticulum stress in visceral fat adipocytes of obese mice	25
Is there a link between vitamin D status, SARS‐CoV‐2 infection risk and COVID‐19 severity?	22
Mammalian target of rapamycin (mTOR) signaling pathway and traumatic brain injury: A novel insight into targeted therapy	22
Abnormal neuronal damage and inflammation in the hippocampus of kainic acid‐induced epilepsy mice	19
Menstrual blood CD146⁺ mesenchymal stem cells reduced fibrosis rate in the rat model of premature ovarian failure	19
Macrophage efferocytosis in health and disease	19
microRNAs in female infertility: An overview	18
The role of fatty acid amide hydrolase enzyme inhibitors in Alzheimer's disease	18
In vitro exosomal transfer of Nrf2 led to the oxaliplatin resistance in human colorectal cancer LS174T cells	18
Inhibition of extracellular vesicle biogenesis in tumor cells: A possible way to reduce tumorigenesis	17
Immunomodulatory effects of phytosomal curcumin on related‐micro RNAs, CD200 expression and inflammatory pathways in dental pulp stem cells	16
Bile acid‐based advanced drug delivery systems, bilosomes and micelles as novel carriers for therapeutics	16
The tumorigenic and therapeutic functions of exosomes in colorectal cancer: Opportunity and challenges	15
Evaluating the effect of secretome of human amniotic mesenchymal stromal cells on apoptosis induction and epithelial‐mesenchymal transition inhibition in LNCaP prostate cancer cells based o	15
Genetic and epigenetic control of ACE2 expression and its possible role in COVID‐19	14
Hypoxia as a modulator of cytochromes P450: Overexpression of the cytochromes CYP2S1 and CYP24A1 in human liver cancer cells in hypoxia	14

Demethyleneberberine promotes apoptosis and suppresses TGF‐β/Smads induced EMT in the colon cancer cells HCT‐116	14
Melatonin: A smart molecule in the DNA repair system	14
Microarray and in silico analysis of DNA repair genes between human testis of patients with nonobstructive azoospermia and normal cells	13
Icariin alleviatesMSU‐induced ratGAmodels throughNF‐κB/NALP3pathway	12
Cellular and molecular mechanism in neurodegeneration: Possible role of neuroprotectants	12
The involvement of a chemokine receptor antagonist CTCE‐9908 and kynurenine metabolites in cancer development	12
Screening of Cu₄O₃ NPs efficacy and its anticancer potential against cervical cancer	12
Could inhibition of metalloproteinases be used to block the process of metastasis?	11
Telomerase‐based therapies in haematological malignancies	11
Melatonin alleviates d‐galactose‐decreased hyaluronic acid production in synovial membrane cells via Sirt1 signalling	11
Osteogenic differentiation potential of human bone marrow‐derived mesenchymal stem cells enhanced by bacoside‐A	11
Distinct glycolytic pathway regulation in liver, tumour and skeletal muscle of mice with cancer cachexia	10
Nonenzymatic glycosylation of isolated human immunoglobulin‐G by D‐ribose	10
Role of marijuana components on the regenerative ability of stem cells	10
Moving beyond nanotechnology to uncover a glimmer of hope in diabetes medicine: Effective nanoparticle‐based therapeutic strategies for the management and treatment of diabetic foot ulcers	10
Pharmacological inhibition of UPR sensor PERK attenuates HIV Tat‐induced inflammatory M1 phenotype in microglial cells	10
Metformin suppresses self‐renewal and stemness of cancer stem cell models derived from pluripotent stem cells	10
Interaction of membrane‐embedded cytochrome b‐complexes with quinols: Classical Q‐cycle and murburn model	10
Simultaneous proteasome and autophagy inhibition synergistically enhances cytotoxicity of doxorubicin in breast cancer cells	10
Antimicrobial peptides derived from microalgae for combating antibiotic resistance: Current status and prospects	9
Dieckol induces cell cycle arrest by down‐regulating CDK2/cyclin E in response to p21/p53 activation in human tracheal fibroblasts	9
Epigenetics and mitochondrial dysfunction insights into the impact of the progression of non‐alcoholic fatty liver disease	9
Metformin encapsulated gold nanoparticles (MTF‐GNPs): A promising antiglycation agent	9
Autophagy in tooth: Physiology, disease and therapeutic implication	9
Cadherins and the pathogenesis of epilepsy	9
Evidence that cervical cancer cells cultured as tumorspheres maintain high CD73 expression and increase their protumor characteristics through TGF‐β production	9
PTPN6 promotes chemosensitivity of colorectal cancer cells via inhibiting the SP1/MAPK signalling pathway	9
TTP488 ameliorates NLRP3‐associated inflammation, viability, apoptosis, and ROS production in an Alzheimer's disease cell model by mediating the JAK1/S	8
Vanillin attenuates thioacetamide‐induced renal assault by direct and indirect mediation of the TGFβ, ERK and Smad signalling pathways in rats	8
Molecular structure, gene expression and functional role of WFDC1 in angiogenesis and cancer	8
Potential targets of severe acute respiratory syndrome coronavirus 2 of clinical drug fluvoxamine: Docking and molecular dynamics studies to elucidate viral action	8
Sulindac and vitamin D3 synergically inhibit proliferation of MCF‐7 breast cancer cell through AMPK/Akt/β‐catenin axis in vitro	8
Carotenoid pigment of Halophilic archaeon Haloarcula sp. A15 induces apoptosis of breast cancer cells	8
Long non‐coding RNA FAM83H‐AS1 as an emerging marker for diagnosis, prognosis and therapeutic targeting of cancer	7
S100A6 represses Calu‐6 lung cancer cells growth via inhibiting cell proliferation, migration, invasion and enhancing apoptosis	7
NK cell dysfunction is linked with disease severity in SARS‐CoV‐2 patients	7
The protective effect of metformin against testicular damage in diabetes and prostate cancer model	7
An overview of long noncoding RNAs: Biology, functions, therapeutics, analysis methods, and bioinformatics tools	7
Therapeutic role of hesperidin in collagen‐induced rheumatoid arthritis through antiglycation and antioxidant activities	7
Curcumin, its derivatives, and their nanoformulations: Revolutionizing cancer treatment	6
Tissue engineering innovations to enhance osseointegration in immediate dental implant loading: A narrative review	6
Dynamic expression of H19 and MALAT1 and their correlation with tumor progression biomarkers in a multistage hepatocarcinogenesis model	6
Diphlorethohydroxycarmalol inhibits melanogenesis via protein kinase A/cAMP response element‐binding protein and extracellular signal‐regulated kinase‐mediated microphthalmia‐associated transcription	6
Polycaprolactone‐co‐polylactic acid nanofiber scaffold in combination with 5‐azacytidine and transforming growth factor‐β to induce cardiomyocyte differentiation of adipose‐derived mesenchymal	6
Inhibition of TGF‐β type I receptor by SB505124 down‐regulates osteoblast differentiation and mineralization of human mesenchymal stem cells	6
Nano‐based methods for novel coronavirus 2019 (2019‐nCoV) diagnosis: A review	6
Advances on biological functions of exosomal non‐coding RNAs in osteoarthritis	6
Antidiabetic effects of quercetin and liraglutide combination through modulation of TXNIP/IRS‐1/PI3K pathway	6
Application of exosomes for the alleviation of COVID‐19‐related pathologies	6
Structural and functional insights on vitamin D receptor and CYP24A1 deleterious single nucleotide polymorphisms: A computational and pharmacogenomics perpetual approach	6

The diterpene Manool extracted from Salvia tingitana lowers free radical production in retinal rod outer segments by inhibiting the extramitochondrial F₁F_o ATP syntha	5
Target‐based virtual screening, computational multiscoring docking and molecular dynamics simulation of small molecules as promising drug candidate affecting kinesin‐like protein KIFC1	5
Immunological substrates of depressive symptoms in patients with severe obesity: An exploratory study	5
Antiglycation potential of plant based TiO₂ nanoparticle in D‐ribose glycated BSA in vitro	5
Oral administration of botryosphaeran [(1 → 3)(1 → 6)‐β‐d‐glucan] reduces inflammation through modulation of leukocytes and has limited effect on inflammatory nociception	5
Biomarker discovery in highly invasive lung cancer cell through proteomics approaches	5
The protective effect of aqueous extract ofStevia rebaudianaagainst tartrazine toxicity in male Wistar rat	5
Structure of PD1 and its mechanism in the treatment of autoimmune diseases	5
The cardioprotective effect of human glucagon‐like peptide‐1 receptor agonist (semaglutide) on cisplatin‐induced cardiotoxicity in rats: Targeting mitochondrial functions, dynamics, biogenesis, and re	5
Curcumin promotes apoptosis of human melanoma cells by caspase 3	5
CNTs‐CaP/chitosan‐coated AZ91D magnesium alloy extract promoted rat dorsal root ganglia neuron growth via activating ERK signalling pathway	5
Novel nucleolar localization of clusterin and its associated functions in human oral cancers: An in vitro and in silico analysis	5
Regulation of radiation‐induced liver damage by modulation of SIRT‐1 activity: In vivo rat model	5
The effects of biophysical stimulation on osteogenic differentiation and the mechanisms fromncRNAs	5
Rab34 plays a critical role as a bidirectional regulator of osteoclastogenesis	5
Biological insights into the rapid tissue regeneration of freshwater crayfish and crustaceans	5
An in vitro investigation of l‐kynurenine, quinolinic acid, and kynurenic acid on B16 F10 melanoma cell cytotoxicity and morphology	5
Modulating Nrf2 transcription factor activity: Revealing the regulatory mechanisms of antioxidant defenses during hibernation in 13‐lined ground squirrels	5
An overview of extracellular matrix and its remodeling in the development of cancer and metastasis with a glance at therapeutic approaches	5
BMP11 regulates thermogenesis in white and brown adipocytes	4
miR‐142‐3p/5p role in cancer: From epigenetic regulation to immunomodulation	4
Improved biological behaviours and osteoinductive capacity of the gelatin nanofibers while composites with GO/MgO	4
Evaluation of the protective role of resveratrol against sepsis caused by LPS via TLR4/NF‐κB/TNF‐α signaling pathways: Experimental study	4
Development of skeletal muscle fibrosis in a rodent model of cancer cachexia	4
Circular RNAs in childhood‐related diseases and cancers: A review	4
Proteomic analysis of thyroid tissue reveals enhanced catabolic activity in Graves' disease compared to toxic multinodular goitre	4
Gene therapy approaches for GM1 gangliosidosis: Focus on animal and cellular studies	4
Elucidation of the changes occurring at the proteome level in ovaries of high‐fat diet‐induced obese rats	4
Impact of dietary supplementation with chokeberry (Aronia melanocarpa, Michx.) on tetrachloride‐induced liver injury in Wistar rats: Hematological and biochemical implication	4
Antioxidant, anti‐inflammatory and beneficial metabolic effects of botryosphaeran [(1→3)(1→6)‐β‐d‐glucan] are responsible for its anti‐tumour activity in experimental non‐obese and obese ra	4
The fucose‐specific lectin ANL from Aspergillus niger possesses anti‐cancer activity by inducing the intrinsic apoptosis pathway in hepatocellular and colon cancer cells	4
AMP‐activated protein kinase is a key regulator of obesity‐associated factors	4
Copy number and expression of CEP89, a protein required for ciliogenesis, are increased and predict poor prognosis in patients with ovarian cancer	4
Cemtirestat, an aldose reductase inhibitor and antioxidant compound, induces ocular defense against oxidative and inflammatory stress in rat models for glycotoxicity	4
Hypericum alpestre extract exhibits in vitro and in vivo anticancer properties by regulating the cellular antioxidant system and metabolic pathway of L‐arginine	4
Sirtuins and autophagy in lipid metabolism	4
Prospective in vitro A431 cell line anticancer efficacy of zirconia nanoflakes derived from Enicostemma littorale aqueous extract	3
Constitutive activation of Notch signalling and T cell activation characterize a mouse model of autism	3
Chronic nitrate administration increases the expression the genes involved in the browning of white adipose tissue in female rats	3
Prediction of surfactin fermentation with Bacillus subtilis DSM10 by response surface methodology optimized artificial neural network	3
One carbon metabolism and its implication in health and immune functions	3
Chronic asthmatic condition modulated the onset of aging in bone marrow mesenchymal stem cells	3
The effect of photobiomodulation therapy in common maxillofacial injuries: Current status	3
Curcumin inhibits human cancer cell growth and migration through downregulation of SVCT2	3
ZnO nanomaterials target mitochondrial apoptosis and mitochondrial autophagy pathways in cancer cells	3
Gluconeogenesis is reduced from alanine, lactate and pyruvate, but maintained from glycerol, in liver perfusion of rats with early and late sepsis	3
Apoptotic profiling of chronic myeloid leukaemia patients' platelets ex vivo before and after treatment with Imatinib	3
Distinct kinetics for nucleotide hydrolysis in lymphocytes isolated from blood, spleen and cervical lymph nodes: Characterization of ectonucleotidase activity	3
Systemic redox imbalance in severe COVID‐19 patients	3
Spermidine promotes melanin production through an MITF signalling pathway	3
Ameliorative effect of sesame oil on experimentally induced polycystic ovary syndrome: A cross‐link between XBP‐1/PPAR‐1, regulatory proteins for lipogenesis/steroids	3
Dauricine exhibits anti‐inflammatory property against acute ulcerative colitis via the regulation of NF‐κB pathway	3
Interplay between membrane proteins and membrane protein‐lipid pertaining to plant salinity stress	3
Dental pulp stem cell secretome ameliorates d‐galactose induced accelerated aging in rat model	3
Long noncoding RNA H19 in ovarian biology and placenta development	3
A three‐dimensional microenvironment alters CD73 expression in cervical cancer	3
Vitamin D and lactoferrin attenuate stress‐induced colitis in Wistar rats via enhancing AMPK expression with inhibiting mTOR–STAT3 signaling and modulating autophagy	3
Effect of 2‐methoxyestradiol treatment on early‐ and late‐stage breast cancer progression in a mouse model	3
Impact of curcumin on ferroptosis‐related genes in colorectal cancer: Insights from in‐silico and in‐vitro studies	3
Long non‐coding RNAs and microorganism‐associated cancers	3
Development of an efficient method for selection of stable cell pools for protein expression and surface display with Expi293F cells	3
Functions and mechanism of noncoding RNA in regulation and differentiation of male mammalian reproduction	3
PDLIM2 can inactivate the TGF‐β/Smad pathway to inhibit the malignant behavior of ovarian cancer cells	3
Tumor cells‐derived exosomal noncoding RNAs in cancer angiogenesis: Molecular mechanisms and prospective	3
SGLT2 inhibitors and autophagy in diabetes	3
OGD/R‐induced ferroptosis and pyroptosis in retinal pigment epithelium cells: Role of PLD1 and PLD2 modulation	3
Development of venetoclax performance using its new derivatives on BCL‐2 protein inhibition	3
Human adipose‐derived stromal/stem cells are distinct from dermal fibroblasts as evaluated by biological characterization and RNA sequencing	3
FNDC5/Irisin protects neurons through Caspase3 and Bax pathways	3
MicroRNA transcriptomics in liver of the freeze‐tolerant gray tree frog (Dryophytes versicolor) indicates suppression of energy‐expensive pathways	3
In silico analysis and verification of critical genes related to vascular calcification in multiple diseases	3
Salivary microbiome in kidney diseases: A narrative review	3
Cell viability and cytotoxicity assays: Biochemical elements and cellular compartments	3
Anti‐inflammatory effect of polydeoxyribonucleotides (PDRN) extracted from red alga (Porphyra sp.) (Ps‐PDRN) in RAW 264.7 macrophages stimulated with Escherichia coli lipopolysaccharides	3
Functional role of SAP18 protein: From transcriptional repression to splicing regulation	3