OOIR: Observatory of International Research

Papers

(The median citation count of Clinical & Experimental Metastasis is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Understanding the cell survival mechanism of anoikis-resistant cancer cells during different steps of metastasis	39
Cancer cell metabolic plasticity in migration and metastasis	39
Breast cancer liver metastasis: current and future treatment approaches	38
TGFβ signaling networks in ovarian cancer progression and plasticity	29
Histopathological growth patterns as biomarker for adjuvant systemic chemotherapy in patients with resected colorectal liver metastases	27
Mechanisms of breast cancer metastasis	25
Molecular and cellular mechanisms controlling integrin-mediated cell adhesion and tumor progression in ovarian cancer metastasis: a review	25
Collective metastasis: coordinating the multicellular voyage	24
Molecular mechanisms of cancer metastasis via the lymphatic versus the blood vessels	24
Distinguishing pure histopathological growth patterns of colorectal liver metastases on CT using deep learning and radiomics: a pilot study	24
Growth differentiation factor 15 (GDF15) in cancer cell metastasis: from the cells to the patients	24
Type IV collagen as a potential biomarker of metastatic breast cancer	23
CXCL2-CXCR2 axis mediates αV integrin-dependent peritoneal metastasis of colon cancer cells	22
Correlation of exosomal microRNA clusters with bone metastasis in non-small cell lung cancer	22
The lymphatic system and sentinel lymph nodes: conduit for cancer metastasis	22
Cancer heterogeneity and metastasis: life at the edge	21
Causal Bayesian gene networks associated with bone, brain and lung metastasis of breast cancer	20
Cancer neoantigens as potential targets for immunotherapy	20
Cancer stem cell generation during epithelial-mesenchymal transition is temporally gated by intrinsic circadian clocks	19
Single-fraction radiosurgery versus fractionated stereotactic radiotherapy in patients with brain metastases: a comparative study	18
Role of CD44 isoforms in epithelial-mesenchymal plasticity and metastasis	18
Impact of the COVID-19 pandemic on quality of life and emotional wellbeing in patients with bone metastases treated with radiotherapy: a prospective cohort study	17
Electrochemotherapy of skin metastases from breast cancer: a systematic review	16
EMT-independent detection of circulating tumor cells in human blood samples and pre-clinical mouse models of metastasis	15
The clinical efficacy of PSMA PET/MRI in biochemically recurrent prostate cancer compared with standard of care imaging modalities and confirmatory histopathology: results of a single-centre, prospect	15

Breast cancer disparities in outcomes; unmasking biological determinants associated with racial and genetic diversity	14
Predictors of prognosis of synchronous brain metastases in small-cell lung cancer patients	14
The gastrointestinal microbiota in colorectal cancer cell migration and invasion	14
Nintedanib and a bi-specific anti-VEGF/Ang2 nanobody selectively prevent brain metastases of lung adenocarcinoma cells	13
The role of stereotactic body radiation therapy and its integration with systemic therapies in metastatic kidney cancer: a multicenter study on behalf of the AIRO (Italian Association of Radiotherapy	13
Prognostic influence of the treatment approach for pulmonary metastasis in patients with soft tissue sarcoma	13
Detection of melanoma, breast cancer and head and neck squamous cell cancer sentinel lymph nodes by Tc-99m Tilmanocept (Lymphoseek®)	13
Interconnected high-dimensional landscapes of epithelial–mesenchymal plasticity and stemness in cancer	12
The influence of an enamine usnic acid derivative (a tyrosyl-DNA phosphodiesterase 1 inhibitor) on the therapeutic effect of topotecan against transplanted tumors in vivo	12
Astrocytic IGFBP2 and CHI3L1 in cerebrospinal fluid drive cortical metastasis of HER2+breast cancer	11
Sentinel lymph node biopsy in melanoma: beyond histologic factors	11
Survival outcome and prognostic factors for colorectal cancer with synchronous bone metastasis: a population-based study	11
Wnt/β-catenin/Slug pathway contributes to tumor invasion and lymph node metastasis in head and neck squamous cell carcinoma	11
Secondary lymphedema from cancer therapy	11
Is repeated pulmonary metastasectomy justified?	11
The role of sentinel lymph node mapping in colon cancer: detection of micro-metastasis, effect on survival, and driver of a paradigm shift in extent of colon resection	10
Emerging photoacoustic and thermoacoustic imaging technologies for detecting primary and metastatic cancer and guiding therapy	10
Anti-invasive effects of minoxidil on human breast cancer cells: combination with ranolazine	10
Comparative associations of baseline frailty status and age with postoperative mortality and duration of hospital stay following metastatic brain tumor resection	10
Laser interstitial thermal therapy for in-field recurrence of brain metastasis after stereotactic radiosurgery: does treatment with LITT prevent a neurologic death?	10
FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells	10
Current challenges in metastasis research and future innovation for clinical translation	10
Inhibition of the Axl pathway impairs breast and prostate cancer metastasis to the bones and bone remodeling	9
Detection of cancer metastasis: past, present and future	9
Tumor shedding and metastatic progression after tumor excision in patient-derived orthotopic xenograft models of triple-negative breast cancer	9
miR-106a-5p carried by tumor-derived extracellular vesicles promotes the invasion and metastasis of ovarian cancer by targeting KLF6	9
Phase II trial of high dose stereotactic body radiation therapy for lymph node oligometastases	9
Cancer microenvironment and genomics: evolution in process	9
The role of intraperitoneal chemotherapy in the surgical management of pancreatic ductal adenocarcinoma: a systematic review	9
Hypofractionated frameless gamma knife radiosurgery for large metastatic brain tumors	9
Stereotactic body radiation therapy for adrenal gland metastases: outcome and predictive factors from a multicenter analysis	9
Longitudinal CTCs gene expression analysis on metastatic castration-resistant prostate cancer patients treated with docetaxel reveals new potential prognosis markers	8
Precision oncology for breast cancer through clinical trials	8
Percutaneous isolated hepatic perfusion (chemosaturation) with melphalan following right hemihepatectomy in patients with cholangiocarcinoma and metastatic uveal melanoma: peri- and post-interventiona	8
Downregulation of LINC00886 facilitates epithelial–mesenchymal transition through SIRT7/ELF3/miR-144 pathway in esophageal squamous cell carcinoma	8
SBRT for elderly oligometastatic patients as a feasible, safe and effective treatment opportunity	8
Metastasis prevention: targeting causes and roots	8
Defining the landscape of metabolic dysregulations in cancer metastasis	8
Characterizing perfusion defects in metastatic lymph nodes at an early stage using high-frequency ultrasound and micro-CT imaging	8
Cardiooncology—dealing with modern drug treatment, long-term complications, and cancer survivorship	7
The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO	7
The rise of metastatic bone disease in Ireland	7
Current management of melanoma patients with nodal metastases	7
In-transit metastatic cutaneous melanoma: current management and future directions	6
Adrenal SBRT: a multi-institutional review of treatment outcomes and toxicity	6
Mass spectrometry-based proteomic capture of proteins bound to the MACC1 promoter in colon cancer	6
The role of epigenetic modifications in Colorectal Cancer Metastasis	6
Protective measures for patients with advanced cancer during the Sars-CoV-2 pandemic: Quo vadis?	6
Indwelling pleural catheter versus talc pleurodesis for malignant pleural effusion: a meta-analysis	6
Prostate cancer addiction to oxidative stress defines sensitivity to anti-tumor neutrophils	6

Molecular insights into the interplay between adiposity, breast cancer and bone metastasis	6
Extensive diagnostic work-up for patients with carcinoma of unknown primary	6
Stereotactic body radiotherapy (SBRT) and concomitant systemic therapy in oligoprogressive breast cancer patients	6
Stereotactic body radiotherapy to lymph nodes in oligoprogressive castration-resistant prostate cancer patients: a post hoc analysis from two phase I clinical trials	6
Molecular prognostic indicators in HPV-positive oropharyngeal cancer: an updated review	6
Metastatic profiling of HER2-positive breast cancer cell lines in xenograft models	6
Myeloid derived suppressor cells and the release of micro-metastases from dormancy	6
Comparing the fate of brain metastatic breast cancer cells in different immune compromised mice with cellular magnetic resonance imaging	6
Single-cell RNA-sequencing identifies anti-cancer immune phenotypes in the early lung metastatic niche during breast cancer	6
Histopathological growth patterns of resected non-colorectal, non-neuroendocrine liver metastases: a retrospective multicenter study	6
Long non-coding RNA NRSN2-AS1, transcribed by SOX2, promotes progression of esophageal squamous cell carcinoma by regulating the ubiquitin-degradation of PGK1	6
Serum conversion pattern of SCC-Ag levels between pre- and post-chemoradiotherapy predicts recurrence and metastasis in cervical cancer: a multi-institutional analysis	6
Empowering study of breast cancer data with application of artificial intelligence technology: promises, challenges, and use cases	5
Oligoprogressive castration-resistant prostate cancer treated with metastases-directed stereotactic body radiation therapy: predictive factors for patients’ selection	5
Electrochemotherapy of skin metastases from malignant melanoma: a PRISMA-compliant systematic review	5
Sociocultural incentives for cancer care implementation	5
Cumulative intracranial tumour volume prognostic assessment: a new predicting score index for patients with brain metastases treated by stereotactic radiosurgery	5
JUNB suppresses distant metastasis by influencing the initial metastatic stage	5
The effect of the low stromal ratio induced by neoadjuvant chemotherapy on recurrence patterns in borderline resectable pancreatic ductal adenocarcinoma	5
Exosomal EphA2 promotes tumor metastasis of triple-negative breast cancer by damaging endothelial barrier	5
Arresting metastasis within the microcirculation	5
A study on different therapies and prognosis-related factors for brain metastases in lung adenocarcinoma patients with driver mutation	5
Identification of miR-4510 as a metastasis suppressor of gastric cancer through regulation of tumor microenvironment via targeting GPC3	4
Gemcitabine induces polarization of mouse peritoneal macrophages towards M1-like and confers antitumor property by inducing ROS production	4
Differential regulation of extracellular matrix proteins in three recurrent liver metastases of a single patient with colorectal cancer	4
Risk factors for surgical site infection and association of surgical site infection with survival of lower rectal cancer patients without clinical lateral pelvic lymph node metastasis (clinical Stage	4
Stereobody radiotherapy for nodal recurrences in oligometastatic patients: a pooled analysis from two phase I clinical trials	4
Prediction of pathological fracture in patients with lower limb bone metastasis using computed tomography imaging	4
Stereotactic radiotherapy of nodal oligometastases from prostate cancer: a prisma-compliant systematic review	4
Synchronous peritoneal metastases from lung cancer: incidence, associated factors, treatment and survival: a Dutch population-based study	4
Intraperitoneal drug delivery systems releasing cytostatic agents to target gastro-intestinal peritoneal metastases in laboratory animals: a systematic review	4
Systematic review of stereotactic body radiotherapy for nodal metastases	4
Single‐fraction versus hypofractionated gamma knife radiosurgery for small metastatic brain tumors	4
Is survival really better after repeated lung metastasectomy?	4
Portal vein tumor thrombosis in hepatocellular carcinoma: molecular mechanism and therapy	4
PSMA-guided metastases directed therapy for bone castration sensitive oligometastatic prostate cancer: a multi-institutional study	4
Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems	4
Integrating stereotactic body radiation therapy (SBRT) and systemic treatments in oligoprogressive prostate cancer: new evidence from the literature	4
Data mining of key genes expression in hepatocellular carcinoma: novel potential biomarkers of diagnosis prognosis or progression	4
Assessment of incentivizing effects for cancer care frameworks	4
Early biochemical outcomes following PSMA guided approach for bIoCHEmical relapse after prostatectomy-PSICHE trial (NCT05022914): preliminary results	4
Resistance to targeted therapies in acute myeloid leukemia	3
Sufentanil combined with parecoxib sodium inhibits proliferation and metastasis of HER2-positive breast cancer cells and regulates epithelial-mesenchymal transition	3
ADC textural features in patients with single brain metastases improve clinical risk models	3
Innovations in radiotherapy and advances in immunotherapy for the treatment of brain metastases	3
CT based quantitative measures of the stability of fractured metastatically involved vertebrae treated with spine stereotactic body radiotherapy	3
Tako-tsubo syndrome after intraperitoneal hyperthermic chemotherapy (HIPEC) with cisplatin: an unusual complication of cytoreductive surgery plus HIPEC	3
Perfusion defects in non-enlarged metastatic lymph nodes using vessel wall magnetic resonance imaging: Detection performance and diagnostic value	3
Transcription factor c-Myb: novel prognostic factor in osteosarcoma	3
Inhibition of LPS-mediated TLR4 activation abrogates gastric adenocarcinoma-associated peritoneal metastasis	3
The smac mimetic LCL161 targets established pulmonary osteosarcoma metastases in mice	3
Cells in the polyaneuploid cancer cell (PACC) state have increased metastatic potential	3
Development of 131I-ixolaris as a theranostic agent: metastatic melanoma preclinical studies	3
Better pain control with 8-gray single fraction palliative radiotherapy for skeletal metastases: a Bayesian network meta-analysis	3
PITX1 suppresses osteosarcoma metastasis through exosomal LINC00662-mediated M2 macrophage polarization	3
Introduction: Novel Frontiers in Cancer Metastasis	3
Prospective assessment of AR splice variant and PSMA detection on circulating tumor cells of mCRPC patients: preliminary analysis of patients enrolled in PRIMERA trial (NCT04188275)	3
Improved detection of sentinel lymph node metastases allows reliable intraoperative identification of patients with extended axillary lymph node involvement in early breast cancer	3