OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Applied Toxicology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Intestinal Bacterial Dysbiosis and Liver Fibrosis in Mice Through Gut‐Liver Axis and NLRP3 Inflammatory Pathway Caused by Fine Particulate Matter	71
Early‐Life Dietary Exposure to Perfluorooctanoic Acid (PFOA) Through Milk Consumption: A Systematic Review	61
Single and Combined Impact of Environmental Concentrations of Galaxolide (HHCB) and Tonalide (AHTN) on Melanopsis praemorsa <	51
Biosafety Evaluation of 6,7‐Dihydroxy‐3‐(2‐Nitrophenyl)Coumarin in Human Cells	46
FOXA1‐TET1 Mediate the DNA Hypomethylation of IL‐4 Is Involved in Dust Fall PM_2.5 Induced Lung Inflammation	44
Oleanolic acid induces hepatic injury by disrupting hepatocyte tight junction and dysregulation of farnesoid X receptor‐mediated bile acid efflux transporters	43
Thymoquinone Reduces Bisphenol A‐Induced Increases in Apoptosis and Oxidative Toxicity Through the Modulation of TRPM2 Channel Signaling Pathways in Human Granulosa Cells	42
Issue Information	42
The Role of TLR4 in the Intestinal Barrier and Its Relationship With Nanoparticle‐Induced Intestinal Injury	39
A scoping review of evaluations of and recommendations for default uncertainty factors in human health risk assessment	38
The Role of PI3K/AKT/HIF‐1α Pathway in the Effect of Nano‐TiO₂ on Lactate Production in TM4 Cells	38
Emodin disrupts the Notch1/Nrf2/GPX4 antioxidant system and promotes renal cell ferroptosis	36
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Synthesis and Toxicological Evaluation of N‐Nitroso Vildagliptin Amide Impurity in BALB 3T3 Clone Cells	33
Allergenicity, Genotoxicity and Subchronic Toxicity Assessment of IgG Binding Protein LT Produced From Aspergillus oryzae	32
The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells	29
Nicotine as a female reproductive toxicant—A review	27
Dose‐Dependent Hepatorenal Damage Induced by Erythrosine: A Study of Biochemical, Oxidative Stress, DNA Damage, and Histopathological Effects in Wistar Rats	27
Impact of Embryonic Exposure of Atrazine on the Physiological and Behavioral Parameters in Drosophila melanogaster	26
Esculin alleviates lipopolysaccharide (LPS)–induced pneumonia by regulating the USP7/MAPK14 axis	25
Mechanistic Insights Into Skin Permeation: A Physiologically Based Toxicokinetic (PBTK) Approach	24
Rsad2 mediates Bisphenol A‐induced actin cytoskeletal disruption in mouse spermatocytes	23
Impact of Lacosamide, Silver Nanoparticles, and Their PEG‐Conjugates on Life History Traits and Behavioral Responses in para ^bss1 Mutant	23
In Vitro Evaluation of Cadmium‐Induced Phosphate Reabsorption Impairment	23
Use of the TIPS Technique as a Possible Method of Acute Inhalation Toxicity Assessment	23

Bile Acid Glycochenodeoxycholic Acid (GCDCA) Might Induce the Loss of Plasma Membrane Integrity and the Release of LDH From Ovarian Granulosa Cells, With Implications in PCOS	22
Issue Information	22
First Biochemical Analysis of the Response of the Scorpion Aegaeobuthus gibbosus (Schenkel, 1947) Upon Exposure to Diflubenzuron	22
Evaluation of possible neuroprotective effects of virgin coconut oil on aluminum‐induced neurotoxicity in an in vitro Alzheimer's disease model	21
Arsenic and Chromium Induced Toxicity on Zebrafish Kidney: Mixture Effects on Oxidative Stress and Involvement of Nrf2‐Keap1‐ARE, DNA Repair, and Intrinsic Apoptotic Pathways	21
Titanium dioxide nanoparticles induce apoptosis through ROS‐Ca²⁺‐p38/AKT/mTOR pathway in TM4 cells	20
Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii	19
Issue Information	18
Preclinical Toxicological Assessment of 2‐(Benzoxazol‐2‐yl)[(2‐hydroxynaphthyl)diazenyl]phenol Derivatives for Blue Light and UV Radiation Photoprotection Applications	18
Protective Effects of 2‐(Thiophen‐2‐yl)‐2,3‐Dihydrobenzothiazole Against Rotenone‐Induced Multi‐Organ Toxicity in Sprague–Dawley Rats	18
Pulmonary Side Effects Associated With Abemaciclib the Antibreast Cancer Drug in Female Mice	18
Monosodium Glutamate Exposure and Liver Damage: Modulatory Effects of L‐Carnitine on Inflammation and Autophagy	18
Toxicological Impacts of Arecoline and Tobacco in Oral Submucous Fibrosis: Mechanisms and Therapeutic Insights	17
Exposure to Polyethylene Terephthalate Microplastic Induces Mouse Liver Fibrosis Through Oxidative Stress and p38 MAPK/p65 NF‐κB Signaling Pathway	17
Protective Role of Polydatin Against Vancomycin‐Induced Lung Toxicity via Oxidative Stress, Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Ferroptosis Pathways	17
Oral Administration of Cadmium Chloride Induces Oxidative Stress, DNA Damage and Histopathological Changes in Rat Intestine: A Dose‐Dependent Study	17
Realgar‐induced nephrotoxicity via ferroptosis in mice	16
Oxidative Stress in Kidney of Zebrafish due to Individual and Combined Exposure to Amoxicillin, Arsenic, and Fluoride: Involving Nrf2‐Keap1‐ARE Pathway	16
Deciphering the Impact of Eriochrome Black T on Tubular Air Sac of Heteropneustes fossilis and Den	16
Flame retardant, hexabromocyclododecane, increases production of pro‐inflammatory cytokines, interleukin 1‐beta and interleukin 6, in human immune cells	16
Black Carbon, Oxidative Potential, and Zebrafish Toxicity: A Toxicological Study of PM _2.5 in Tennessee	16
The Relationship Between Mercury Exposure and Membranous Nephropathy: Case Reports and Meta‐Analysis	15
Issue Information	15
Antitumor Cytotoxic Activity Retained in Tolerized T Cells Following Daily Dose Escalation of a T‐Cell Engager in Cynomolgus Monkeys to Mitigate Cytokine Release Syndrome	14
The role of receptor‐mediated activities of 4‐ and 5‐ring unsubstituted and methylated polycyclic aromatic hydrocarbons (PAHs) in developmental toxicity	14
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How Antiepileptic Carbamazepine Affects the Aquatic System: Acute and Sublethal Toxicity on the Narrow‐Clawed Crayfish Pontastacus leptodactylus	14
The role of phenothiazine derivatives in autophagy regulation: A systematic review	14
2D‐Quantitative structure–activity relationship modeling for risk assessment of pharmacotherapy applied during pregnancy	14
Issue Information	14
Quercetin ameliorates Helicobacter pylori‐induced gastric epithelial cell injury by regulating specificity protein 1/lipocalin 2 axis in gastritis	13
Cellular Responses to Tartrazine and Sulfanilic Acid Exposure in BEAS‐2B Cells: Viability, Apoptosis, and DNA Damage	13
A Brief Review of the Role of Macrophage Hypoxia in SiO ₂ ‐Induced Pulmonary Fibrosis	13
Bacillus subtilis ZB423: 90‐Day repeat dose oral (gavage) toxicity study in Wistar rats	13
A 90‐day preclinical toxicological evaluation in rats of a highly purified and concentrated mulberry leaf extract	13
Toxicological Evaluation of the Sweet Protein Brazzein Derived From Komagataella phaffii for Use a	13
Revealing the Risks: A Review on the Toxicity and Mechanisms of Biodegradable Microplastics in Terrestrial Mammals	13
Bifenthrin Under Scrutiny: Revisiting Toxicological Evidence Amid Regulatory Gaps	13
Safety assessment of a solid lipid curcumin particle preparation: In vitro and in vivo genotoxicity studies	13
Hydrogen sulfide alleviates beryllium sulfate‐induced ferroptosis and ferritinophagy in 16HBE cells	12
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Study of Serum Metabolic Biomarkers and Prediction Models of Cantharidin‐Induced Nephrotoxicity in Rats Based on Dynamic Metabolomics	12
The mechanism and effects of remdesivir‐induced developmental toxicity in zebrafish: Blood flow dysfunction and behavioral alterations	12
Issue Information	12
Biological effects of molybdenum(IV) sulfide nanoparticles and microparticles in the rat after repeated intratracheal administration	12
Issue Information	12
Atypical Antipsychotics‐Induced Glucose and Lipid Metabolism Disorders and Therapeutic Intervention	12
Isoflurane preconditioning attenuates OGD/R‐induced cardiomyocyte cytotoxicity by regulating the miR‐210/BNIP3 axis	12
Perfluorooctane sulfonate promotes hepatic lipid accumulation and steatosis in high‐fat diet mice through AMP‐activated protein kinase/acetyl‐CoA carboxylase (AMPK/ACC) pathway	11
Inhibition of voltage‐dependent K⁺ channels in rabbit coronary arterial smooth muscle cells by the atypical antipsychotic agent sertindole	11

Subchronic Inhalation of TiO₂ Nanoparticles Leads to Deposition in the Lung and Alterations in Erythrocyte Morphology in Mice	11
SF‐1 Downregulation and Steroidogenic Disruption in Male Rats Exposed to Silica Nanoparticles (SiO ₂ ) for 90 Days	11
Toxicokinetic Profiles and Potential Endocrine Disruption Effects at the Reproductive Level Promoted by Siloxanes Used in Consumer Products	11
Nuciferine protects hyperandrogen‐injured ovarian granulosa cells by inhibiting ferroptosis via SOX2‐mediated activation of the SLC7A11/GPX4 axis	11
Xylazine‐Adulterated Fentanyl‐Induced Brain Toxicity: Mechanism Elucidation via Network Toxicology and Molecular Docking Approaches	11
Human Relevance of Pharmaceutical Drug‐Induced Thyroid Tumors in Rats, Labeling Implications, and Carcinogenicity Study Requirements	11
Umbelliferone protects against methylglyoxal‐induced HUVECs dysfunction through suppression of apoptosis and oxidative stress	11
Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish	11
Safer and Sustainable Alternatives to Xylene in Histopathology: A Comprehensive Review	11
Mechanistic Evaluation of Chlorfenapyr‐Induced Hepatotoxicity and the Mitigating Actions of Resveratrol‐Loaded Chitosan Nanoparticles	11
Hepatotoxicity of titanium dioxide nanoparticles	11
Lowering the pH leads to the disaggregation of NiO and ZnO nanoparticles and modifies the mutagenic response	10
TCDD Induces Hepatocytes Lipid Deposition via Downregulation of MFN2	10
Novel ferrocene‐containing triacyl derivative of resveratrol improves viability parameters in ovary cells	10
Epithelial–Mesenchymal Transition in Human Alveolar Cells Exposed to Indium Chloride	10
Reimagining Brain Drug Delivery: Mechanistic and Translational Advances in Carbon Nanotube Nanomedicine	10
Investigation of the mechanisms behind ochratoxin A‐induced cytotoxicity in human astrocytes and the protective effects of N‐acetylcysteine	10
Circ_0027470 promotes cadmium exposure‐induced prostatic fibrosis via sponging miRNA‐1236‐3p and stimulating SHH signaling pathway	10
Monocrotophos‐Induced Redox Imbalance and Genotoxicity in Drosophila melanogaster : Implications f	10
Environmentally relevant lead alters nuclear integrity in erythrocytes and generates oxidative stress in liver of Anabas testudineus: Involvement of Nrf2‐Keap1 regulation and express	10
Using particle dimensionality‐based modeling to estimate lung carcinogenicity of 3D printer emissions	10
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Adverse effect of FTY720P on colonic Na⁺/K⁺ ATPase is mediated via ERK, p38MAPK, PKC, and PI3K	10
Dietary Exposure and Chronic Health Risks of Beverage Preservatives: A Multimatrix HPLC Assessment in Erbil, Kurdistan‐Iraq	10
Evaluating Solvent Safety in Chromosome Aberration Assays for Genetic Toxicology	10
Correction to “Cobalt Oxide Nanoparticles Induced Oxidative Stress Linked to Activation of TNF‐α/Caspase‐8/p38‐MAPK Signaling in Human Leukemia Cells”	10
Branched‐Chain Amino Acids Alleviate Carbon Tetrachloride–Induced Kidney Fibrosis and Splenic Hemorrhage in Rat Models	10
Cell Toxicity and Autophagy in A549 Cells Treated With Surface‐Functionalized Graphene Derivatives	9
Green Synthesis of Silver‐Zinc Oxide Nanocomposites Using Spirulina platensis Biomass: Characterization and Biomedical Evaluation	9
In silico prediction of ocular toxicity of compounds using explainable machine learning and deep learning approaches	9
The Impact of NO₂ on Epithelial Barrier Integrity of a Primary Cell‐Based Air–Liquid Interface Model of the Nasal Respiratory Epithelium	9
The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review	9
Cadmium as an ovarian toxicant: A review	9
Associations of bisphenol F and S, as substitutes for bisphenol A, with cardiovascular disease in American adults	9
Mulberrin extends lifespan in Caenorhabditis elegans through detoxification function	9
A systematic review on multipotent carcinogenic agent, N‐nitrosodiethylamine (NDEA), its major risk assessment, and precautions	9
A regression analysis using simple descriptors for multiple dermal datasets: Going from individual membranes to the full skin	9
Samarium Oxide Exposure Induces Toxicity and Cardiotoxicity in Zebrafish Embryos Through Apoptosis Pathway	9
Oxidative Stress and Structural Damage Underlie Hepatic, Renal, and Intestinal Toxicity of Dodine in Rats Following Subacute Exposure	9
The Genotoxic Ambiguity of 4‐Aminoquinolines: Resolving Hydroxychloroquine's Mechanistic Safety Profile Through Integrated Toxicology Assessment	9
Transgenerational Reproductive and Developmental Toxicity Induced by N‐Nitrosodimethylamine and Its Metabolite Formaldehyde in Drosophila melanogaster	9
The Molecular Mechanism of miRNA‐195‐5p Regulating ERK Involvement in Abnormal Phosphorylation of Tau Protein by Aluminum Maltol in PC12 Cells	9
In vitro evaluation of the inhalation toxicity of the cosmetic ingredient aluminum chlorohydrate	9
New Hydrazone Derivatives Featuring Isatin and Piperazine Moieties: Synthesis, Cytotoxicity Evaluation, and Molecular Modeling Studies	9
Issue Information	8
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Safety Assessment of Butyric Acid‐Rich Triglyceride Oil: A Novel Palatable Formulation of Butyrate for the Pediatric Population	8
Research on the Mechanism of LncMSTRG.5686.1/let‐7a‐5p Regulating Cognitive Function Alteration Induced by Neodymium Nitrate Exposure During Pregnancy and Lactation in Offspring Rats and Mediating Mit	8
Evaluation of Detoxification‐Related Gene Expression, Oxidative Stress Biomarkers, and Blood Biochemical Parameters in Common Carp ( Cyprinus carpio<	8
Toxicity evaluation of main zopiclone impurities based on quantitative structure–activity relationship models and in vitro tests	8
Assessment of commercial polymers with and without reactive groups using amino acid derivative reactivity assay based on both molar concentration approach and gravimetric approach	8
Transcriptome Analysis Suggests Chronic Toxic Effects of 1‐Ethyl‐3‐(3‐Dimethylaminopropyl)carbodiimide in Daphnia magna	8
Disruption of neurosteroid synthesis and release by tris(2,3‐dibromopropyl)isocyanurate in primary mouse cortical astrocytes in vitro	8
Glycyrrhetinic acid ameliorates diosbulbin B‐induced hepatotoxicity in mice by modulating metabolic activation of diosbulbin B	8
A proposed in vitro cytotoxicity test battery to detect and predict hepatotoxicity via multiple mechanisms and pathways: a minireview	8
Environmental Aromatic Amine Induces Pulmonary Arterial Hypertension Associated With Estrogen Signaling and Serpine1	8
Impacts of Inorganic Arsenic Exposure on Genetic Stability of Human Mesenchymal Stromal Cells	8
Assessing the Sublethal Effects of Dibutyl Adipate on Unio Delicatus : Biochemical and Histopathol	8
Issue Information	8
Antioxidant dihydrolipolic acid protects against in vitro aluminum‐induced toxicity	8
Cigarette smoke interacts with amiodarone toxicity in Saccharomyces cerevisiae	8
Histopathological Effects of Anthropogenic Toxic Element Pollution in Freshwater Fishes in Their Natural Environments: A Global Review	7
Caenorhabditis elegans CYP33 Family in Eicosanoid Regulation, Xenobiotic Metabolism, Nanotoxicity and Spermatogenesis	7
A development of a graph‐based ensemble machine learning model for skin sensitization hazard and potency assessment	7
Anti‐Candida activity and in vitro toxicity screening of antifungals complexed with β‐cyclodextrin	7
Liquiritin alleviates alpha‐naphthylisothiocyanate‐induced intrahepatic cholestasis through the Sirt1/FXR/Nrf2 pathway	7
Time‐course analysis of pulmonary inflammation induced by intratracheal instillation of nanosized crystalline silica particles in F344 rats	7
Colchicine disrupts bile acid metabolic homeostasis by affecting the enterohepatic circulation in mice	7
Revealing the Impact of Mono(2‐ethylhexyl) Phthalate (MEHP) on Prostate Cancer Based on Network Toxicology and Molecular Docking Approaches	7
Impact of Oxidative Stress on Reproductive Toxicity Induced by Alpha‐Terpineol in Male Sprague–Dawley Rats	7
CYP14 family in Caenorhabditis elegans: Mitochondrial function, detoxification, and lifespan	7
Paraquat Dichloride Induced Cytotoxicity in Primary Hepatocytes via an Antioxidative and Mitochondrial‐Dependent Pathway	7
The effects of natural products and bioactive ingredients of traditional Chinese medicine on apoptosis of ovarian granulosa cells	7
In silico prediction of chemical aquatic toxicity by multiple machine learning and deep learning approaches	7
Developmental Multi‐Organ Toxicity in Zebrafish Exposed to 1, 2‐Dichloroethane	7
Toxicological effects of selenium nanoparticles in laboratory animals: A review	7
Irisin and Exercise Ameliorate the Polyethylene Microplastics–Induced Blood–Testis Barrier Disruption via PGC‐1α Activation and AMPK/Nrf2/HO‐1 Signaling	6
Leukemia Inhibitory Factor via JAK‐STAT Signaling Drives Beryllium Sulfate–Induced Epithelial–Mesenchymal Transition in 16HBE Cells	6
Comparative Developmental Toxicity of Roxithromycin in Danio rerio and Xenopus laevis	6
Non‐clinical safety evaluation of Yongdamsagan‐tang water extract: A 13‐week subchronic oral toxicity study in Sprague Dawley rats	6

Developmental and reproductive toxicity hazard characterization of 2‐amino‐2‐methyl‐1‐propanol (AMP)	6
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Physiologically‐based pharmacokinetic model of in vitro porcine ear skin permeation for drug delivery research	6
Human Neurotoxicity of Trichloroethylene: A Biomarker Approach	6
Dipicolinic Acid Exerts a Cardioprotective Effect Through Its Regulation of the Functioning of the Glutathione‐Dependent Antioxidant System and Apoptosis in Diclofenac‐Induced Myocardial Injury	6
Evaluating the Genotoxicity and Mutagenicity of Food Contaminants: Acrylamide, Penitrem A, and 3‐Acetyldeoxynivalenol in Individual and Combined Exposure In Vitro	6
Epigenetic alternations in the SYP and DLG4 genes due to low‐level methylmercury exposure during neuronal differentiation in vitro	6
Issue Information	6
Evaluation of immunotoxicity of sodium metavanadate following drinking water exposure in female B6C3F1/N mice in a 28‐day study	6
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Effect of renal tubular damage on non‐cancer mortality in the general Japanese population living in cadmium non‐polluted areas	6
Balancing Efficacy, Toxicological Selectivity and Yield Response of Insecticides Against the Invasive Spiralling Whitefly Aleurodicus dispersus	6
mtDNA amplifies beryllium sulfate‐induced inflammatory responses via the cGAS‐STING pathway in 16HBE cells	6
Toxicology and safety study of L‐tryptophan and its impurities for use in broiler feed	6
Oral exposure to citrinin significantly exacerbates the pathophysiology of a mouse model of imiquimod‐induced psoriasis via direct activation of dendritic cell	6
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Exposure to thiourea during the early stages of development impedes the formation of the swim bladder in zebrafish larvae	5
Pathophysiological Effects of the North Africa's Dangerous Scorpions and Antivenom Neutralization Efficacity: Unveiling the Spleen's Response	5
Novel Toxicokinetics and Metabolic Insights Into Arsenic in Biological Systems From Realgar– Indigo naturalis Formula	5
Polystyrene Nanoparticles Induce Transcriptional Repression in TM4 Sertoli Cells	5
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Review of Organophosphorus Herbicide: Distribution of Residues, Toxicity Effects, Mechanisms, and Developing Trends Studies	5
Evidence for exposure biomarkers in dictamnine‐induced liver injury resulting from metabolic activation in vitro and in mice	5
Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐	5
In vitro exposure of porcine spermatozoa to methylparaben, and propylparaben, alone or in combination adversely affects sperm quality	5
Particle surface functionalization affects mechanism of endocytosis and adverse effects of silver nanoparticles in mammalian kidney cells	5
Oxidative DNA damage contributes to usnic acid‐induced toxicity in human induced pluripotent stem cell‐derived hepatocytes	5
The toxicological effects of nano titanium dioxide on target organs and mechanisms of toxicity	5
Dysregulation of mTOR , GADD45a , and CDKN1A in HepG2/C3A S	5
Issue Information	5
A novel alternative method for long‐term evaluation of male reproductive toxicity and its recovery using a pre‐pubertal mouse testis organ culture system	5
90‐day oral toxicity study in rats of a protein‐rich powder derived from Xanthobacter sp. SoF1	5
Thyroid Endocrine Disrupting Potential of Fluoxetine in Zebrafish Larvae	5
Impact of Methylparaben on Cumulus Cell DNA Integrity and Porcine Oocyte Developmental Competence In Vitro	5
Issue Information	5
CdTe quantum dots trigger oxidative stress and endoplasmic reticulum stress‐induced apoptosis and autophagy in rat Schwann cell line RSC96	5
Protective Effects of Atorvastatin on LPS‐Induced Testicular Damage: Modulation of Spermatogenesis via PPAR‐γ, NF‐κB, and NLRP3 Pathways	5
Oxidative Stress Biomarkers in Gasoline Station Workers Chronically Exposed to Heavy Metals in Erbil City	5
Comparison of the sensitivity of histopathological and immunohistochemical analyses and blood hormone levels for early detection of antithyroid effects in rats treated with thyroid peroxidase inhibito	5
Methylglyoxal‐induced neurotoxic effects in primary neuronal‐like cells transdifferentiated from human mesenchymal stem cells: Impact of low concentrations	5
Modification of Oxidative Stress Induced by Exposure to Arsenate in Rat Chondrocytes Treated With Chitosan–Glutathione Nanoparticles	5
Disruption of vitamin A homeostasis by the biocide tetrakis(hydroxymethyl) phosphonium sulphate in pregnant rabbits	5
Impact of Industrial Pollution on Human Renal Function and Male Reproductive Hormones: An Investigation of Heavy Metals Toxicity and Oxidative Stress	5
Screening potential anaphylactoid components in vinpocetine injection using a high expression Mas‐related G‐protein‐coupled receptor X2 cell membrane chromatography	5
Bisphenol A Induces Endothelial Dysfunction via Oxidative Stress–Driven Ferroptosis and Nrf2 Suppression	4
Molluscicidal activity of plant alkaloids	4
Chronic low‐dose chromium VI exposure induces oxidative stress and apoptosis with altered expressions of DNA repair genes and promoter hypermethylation in the liver of Swiss albino mice	4
LIN‐24 as a Molecular Switch: Dual Cytotoxic and Cytoprotective Roles of an Aerolysin‐Like Protein in C. elegans	4
In vitro toxicity evaluation in A549 cells of diesel particulate matter from two different particle sampling systems and several resuspension media	4
Subchronic toxicity evaluation of Huobahuagen extract and plasma metabolic profiling analysis combined with conventional pathology methods	4
Physiologically based pharmacokinetic modeling and simulation of cannabinoids in human plasma and tissues	4
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Nonclinical safety and immunogenicity assessment of a combined DTacP vaccine in animal models	4
Subchronic Arsenite Exposure Accelerated Skeletal Muscle Aging With Abnormal Corticosterone Secretion in Middle‐Aged Mice	4
The Biocide Triclosan Drives the Inflammatory Responses in Epithelial Cells and Macrophages via ROS‐Mediated Activation of ERK/NF‐κB Signaling Pathways	4
Evaluating the Potentially Toxic Effects of Thrombopoietin Receptor Agonist (Eltrombopag) in Immune Thrombocytopenic Pediatric Patients and Animal Models	4
Di(2‐ethylhexyl) Phthalate Induces Placental Cellular Apoptosis via the PI3K/Akt‐p53 Pathway and Functional Disruption via a ceRNA Network	4
The aryl hydrocarbon receptor pathway is a marker of lung cell activation but does not play a central pathologic role in engineered stone‐associated silicosis	4
Acute Toxicity and Genotoxicity of cMoL, a Lectin From Moringa oleifera Seeds With Antifungal Acti	4
The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Induced by Cigarette Smoke in Humans: A Systematic Review	4
Evaluation of the effect of green tea and its constituents on embryo development in a zebrafish model	4
Research progress on components and mechanisms of neurotoxicity induced by traditional Chinese medicine	4
Comparative Health Risk Assessment of Heavy Metal Contamination in Indoor Dust From University Dormitories in Erbil, Iraq	4
Importance of diet in amphibian metamorphosis‐based studies designed to assess the risk of thyroid active substances	4
Towards Mechanistic QSAR Approaches for Predicting Reactive Oxygen Species (ROS) Generation: Mini Review	4
Toxicological safety assessment of AP‐Bio®, a standardized extract of Andrographis paniculata in Sprague Dawley rats	4
Characterisation of ChE in Solea solea and exposure of isoflavones in juveniles of commercial flatfish (Solea solea and Solea senegalensis)	4
Effect of Ulinastatin Combined With High‐Volume Hemofiltration on Inflammatory Response and MODS Incidence in Severe Sepsis	4
Arsenic‐Induced Inflammatory Response via ROS‐Dependent Activation of ERK/NF‐kB Signaling Pathways: Protective Role of Natural Polyphenol Tannic Acid	4
In silico analysis of endocrine‐disrupting potential of triclosan, bisphenol A, and their analogs and derivatives	4
Brass‐Derived Copper and Zinc Induce Oxidative Stress and Autophagy‐Mediated Nephrotoxicity in Channa punctatus	4
Histopathological and Molecular Alterations in the Liver of Hoplias intermedius (Pisces: Erythrini	4
Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure	4
Effects of Subtoxic Doses of Aflatoxin B ₁ : An In Vitro Assessment of Micronucleus Assay and Induction of Neutrophil Extracellular Traps	4
Benzo(a)pyrene‐7,8‐dihydrodiol‐9,10‐epoxide (BPDE) Induces Ferroptosis in Rat Cortical Neurons via p53‐SLC7A11‐ALOX12/p53‐SAT1‐ALOX15 Pathways	4
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Toxic Effects of CdTe Quantum Dots on Locomotor Behavior, Neurodevelopment, and Axon Growth in Zebrafish Larvae	4
Role of berberine on angiogenesis and blood flow hemodynamics using zebrafish model	4
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The Role of CXCL13 in GC‐1 Cell Cycle Arrest Induced by Titanium Dioxide Nanoparticles Through JAK2/STAT3 Signaling Pathway	4
Chronic Microplastic Exposure Dose‐Dependently Induces Liver Failure via Oxidative Stress, Inflammation, and Apoptosis in Rats	4
A novel strategy for the study on molecular mechanism of prostate injury induced by 4,4′‐sulfonyldiphenol based on network toxicology analysis	4
Influence of systemic copper toxicity on early development and metamorphosis in Xenopus laevis	4
Epigallocatechin gallate alleviated the in vivo toxicity of ZnO nanoparticles to mouse intestine	3
Voacangine protects hippocampal neuronal cells against oxygen–glucose deprivation/reoxygenation‐caused oxidative stress and ferroptosis by activating the PI3K‐Akt‐FoxO signaling	3
Characterization of microparticles derived from waste plastics and their bio‐interaction with human lung A549 cells	3
Intratracheal instillation of graphene oxide decreases anti‐virus responses and lipid contents via suppressing Toll‐like receptor 3 in mouse livers	3
Assessment of the bioaccumulation potential of four commonly used phenolic benzotriazoles based on in silico and experimental in vivo data	3
Chlorpyrifos and Bifenthrin Induced Histopathological and Biochemical Alterations in Different Organs of Hypophthalmichthys molitrix	3
Progress on the toxicity of quantum dots to model organism‐zebrafish	3
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Assessing the Biosafety of Chitosan‐Based Nanohybrid Fertilizers: A Multitropic Toxicological Study for Sustainable Agriculture	3
Reconstructed human epidermis‐based testing strategy of skin sensitization potential and potency classification using epidermal sensitization assay and in silico data	3