Indian Journal of Medical Microbiology

Papers
(The median citation count of Indian Journal of Medical Microbiology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Blood borne infections and Hepatitis B virus immunization levels among medical students in India48
Exploring the use of Congo red agar in improving the serotyping of non-serotypeable Shigella with In-silico evidence48
Table of Contents40
Mycotic aneurysm by Bacteroides fragilis presenting as fever of unknown origin23
Molecular characterization of Orientia tsutsugamushi causing fatal scrub typhus in a young male affected by so-called “mystery fever” in North India20
Role of nurse: Patient ratio as a factor in hand hygiene compliance in a tertiary care hospital in North India: Perception versus reality19
Investigation of the presence of Enterocytozoon bieneusi and Encephalitozoon intestinalis in immunosuppressed patients with diarrhea by IFA and real time PCR methods17
Changing epidemiological trend of Aeromonas species and ciprofloxacin sensitivity in South India17
Genome sequence of pan drug-resistant enteroaggregative Escherichia coli belonging to ST38 clone from India, an emerging EAEC/UPEC hybrid pathotype16
Molecular Metamorphosis and clinical ramifications: A study of sequence variants in acute bacterial meningitis16
Development of an enhanced LAMP-based method for early identification of Streptococcus pneumoniae through LytA gene amplification15
Circulation of a single hepatitis A virus genotype IIIA with two distinct clusters in different states of India15
Tinea universalis due to Trichophyton indotineae in an adult male13
Molecular profiling of virulence determinants and antimicrobial resistance in MRSA isolates from HIV-infected and non-HIV individuals13
Pulmonary tuberculosis and neurologic melioidosis coinfection-first case report from Madurai12
Editorial Board12
Varied synergistic activity of colistin and polymyxin B with meropenem, rifampicin and tigecycline: An in vitro study on carbapenem resistant Acinetobacter baumannii from India11
Genomic insights into carbapenem- and colistin-resistant Klebsiella pneumoniae reveal co-occurrence of resistance and virulence determinants in India11
Current trends in antimicrobial resistance of ESKAPEEc pathogens from bloodstream infections – Experience of a tertiary care centre in North India11
A hospital-based epidemiological study of the genes coding for carbapenemase production among carbapenem resistant Acinetobacter isolates in India11
Rising trend of symptomatic infections due to Hepatitis A virus infection in adolescent and adult age group: An observational study from a tertiary care liver institute in India11
Mapping cervical microbiome diversity and inflammatory milieu and its perturbation in asymptomatic bacterial vaginosis and Candida infections: Insights from a community clinic in Mumbai11
Delhi's network for surveillance of antimicrobial resistance: The journey, challenges and output from first year10
A fatal misidentification: Burkholderia pseudomallei misidentified as Acinetobacter spp10
Strategically reducing carbapenem-resistant Acinetobacter baumannii through PDCA cycle-driven antibiotic management10
Influence of COVID-19 over seasonal influenza activity in southern India10
Outbreak of Burkholderia cenocepacia in an intensive care unit of a tertiary care hospital identified by pulsed-field gel electrophoresis10
Aims and Scope10
Table of Contents9
Beyond the usual suspects: A case report of multi-etiological and multidrug-resistant Candida onychomycosis9
The emergence of Klebsiella pneumoniae sequence type 395 non-susceptible to carbapenems and colistin from Turkey9
A study on candiduria in neonates and infants from a tertiary care center, North India8
Evaluation of an in-house PCR for diagnosing scrub typhus along with a preliminary study of genotypic characterization of Orientia tsutshugamushi circulating in Chhattisgarh: A prospective clinico-mic8
Seroepidemiological and genomic investigation of SARS-CoV-2 spread in North East region of India8
Phenotypic and genomic characterization of a small colony variant of Klebsiella pneumoniae isolated from urine of a prostate cancer case8
Diagnostic utility of LAMP PCR targeting bcsp-31 gene for human brucellosis infection8
The mystery behind a 1000 day fever in a young male8
Cow dung, COVID-19, and mucormycosis … more damned lies8
Comparative evaluation of practical in-vitro methods for testing synergy between ceftazidime-avibactam and aztreonam against metallo-β-lactamase and serine carbapenemase-producing Enterobacterales spe7
Comparative evaluation of colistin broth disc elution (CBDE) and broth microdilution (BMD) in clinical isolates of Pseudomonas aeruginosa with special reference to heteroresistance7
Impact of care bundle audit on compliance to device care bundles and device associated infections in the Critical Care Unit of a tertiary care hospital, Southern India – A before-after interventional 7
Performance of EAST in diagnosing inhalant allergens in children with allergic rhinitis7
Keratitis due to Lasiodiplodia theobromae successfully treated with voriconazole: A case series from Assam7
Diagnosis of mucormycosis from nasal swabs using commercial PCR platforms; a feasible alternative?7
Strengthening antimicrobial stewardship activities in secondary and primary public healthcare facilities in India: Insights from a qualitative study with stakeholders7
Detection of 16S rRNA gene for rapid identification of bacterial pathogens causing peritonitis in patients on continuous ambulatory peritoneal dialysis7
Pulmonary nocardiosis: Risk factors and species distribution from a high burden centre7
Enhancing the diagnostic and surveillance framework for acute encephalitis syndrome in resource-limited settings7
Corrigendum to “Mycoplasma pneumoniae among children hospitalized in a tertiary hospital with community-acquired lower respiratory tract infections” [Indian J Med Microbiol 53 (2025) 100781]7
Fasciolopsis buski isolated from human host, India has distinct clade based on nuclear ribosomal DNA sequences7
Human papillomavirus infection in non-cervical sites in India7
A rare encounter: Tuberculous pyomyositis in an immunosuppressed post-transplant patient6
High public demand and acceptance of newer vaccines in private sector immunisation in Vellore, South India: Implications for India's national immunisation program6
Diagnostic accuracy of urinary lipoarabinomannan antigen detection for the diagnosis of pulmonary and extra pulmonary tuberculosis (EPTB) in HIV negative population6
Adult cutaneous diphtheria by non-toxicogenic strain: Case report and review of literature6
Effect of electric current in viability, biofilm formation and antibiotic resistance of Pseudomonas aeruginosa: A systematic review6
Immunogenicity, safety and efficacy of COVID-19 vaccine: Correspondence6
A co-infection of Pneumocystis jirovecii and Lophomonas blattarum causing pneumonia in a patient with adenocarcinoma of lung6
Forensic Microbiology in India: A missing piece in the puzzle of criminal investigation system6
Current deadly dengue outbreak and serotype displacements in Bangladesh in 20236
Ralstonia pickettii bacteremia: A retrospective review of records6
Pattern of InhA and KatG mutations in isoniazid mono resistant Mycobacterium tuberculosis isolates from Odisha6
Syndromic panel testing- Understanding epidemiology of paediatric diarrhoea to augment antimicrobial stewardship in tertiary health care set-up6
Cytomegalovirus reactivation in a SARS-CoV-2 infected woman experiencing fetal demise in the first trimester with fetal trisomy 21: A case report6
Insights into changing patterns of extrapulmonary tuberculosis in North India6
Pestalotiopsis, a rare cause of mycetoma; A case report5
Exploring the necessity of molecular detection for Streptococcus dysgalactiae subsp equisimilis: Often misdiagnosed, and emerging pathogen5
Comparative evaluation of Vitek®2 and broth microdilution method for colistin susceptibility testing of Gram-negative isolates from intensive care unit in a tertiary care hospital5
Table of Contents5
Aims and Scope5
Comparison of intra-assay and inter-assay reproducibility and positive detection times of two different (BacT/Alert 3D and Autobio BC) commercial blood culture systems5
Aims and Scope5
Isolate profiling and geographical distribution of COVID-19 associated mucormycosis cases presenting to a tertiary care hospital in Jodhpur, India5
Candida infections in COVID-19 patients: A review of prevalence, risk factors, and mortality5
Molecular epidemiology of SARS-CoV-2 in healthcare workers and identification of viral genomic correlates of transmissibility and vaccine break through infection: A retrospective observational study f5
Editorial Board5
Comprehensive analysis of virulence profile and antimicrobial resistance profile of Shigella spp.– over an 8-year study period5
Current trend of biapenem susceptibility and disc diffusion breakpoints in Enterobacterales and Pseudomonas aeruginosa5
Influence of Hepatitis C virus genotype and other factors on the viral load5
Temporal burden of WHO Critical-priority Enterobacteriaceae in the infant gut during early life influenced by maternal postpartum antibiotic exposure5
"The nexus of extensively drug-resistant Gram-negative bacteria and intensive care: Elucidating propagation patterns to fortify infection control measures"5
In vitro activity of the newly approved antimicrobial agent Cefiderocol against Carbapenem resistant Gram negative clinical isolates5
Pseudoparalysis paradox: Think of ‘SCORTCH’5
Synergy testing of ceftazidime-avibactam and aztreonam combination by two different methods5
Table of Contents5
Enterobius vermicularis and Helicobacter pylori coinfection in a geriatric patient on long-term steroids: A case report5
Digital gangrene without sclerodactyly in the presence of anticentromere antibodies: A unique presentation of scleroderma5
An interesting report of COVID-19 associated mucormycosis (CAM) cases by two different species of Mucorales5
Acrophialophora jodhpurensis and Nocardia in idiopathic bronchiectasis: Colonizers or culprits?’5
Utility of quantitative loop mediated isothermal amplification (qLAMP) assay for the diagnosis of invasive pneumococcal disease (IPD)5
The Wolf in Sheep's Clothing: Incidental Pulmonary Hydatidosis masquerading as Constitutional Symptoms5
Candidozyma auris: Identification, antifungal susceptibility, and caspofungin-induced paradoxical growth5
Fungal-associated pneumonia in patients with hematological malignancies4
A novel case of Vibrio bacteremia in an immune-competent patient4
Recurrent MALDI-TOF MS identification failure for Sphingomonas paucimobilis from blood cultures: A single-center observation4
Cerebral sparganosis masquerading brain neoplasm: A rare incidental case4
Use of different stains for microscopic evaluation for the diagnosis of Pythium keratitis4
Discovery of HCV vaccine: Where do we stand?4
Molecular epidemiology of hand, foot, and mouth disease in Karnataka, India in 20224
Editorial Board4
Strongyloides causing diarrhea in a Hepatitis B carrier patient: A case report and review of literature4
Possible impact of revisions in disc diffusion breakpoints for aminoglycosides and piperacillin/tazobactam in the 33rd edition of CLSI M100 document on clinical reporting and use in Indian settings wi4
Current surge of COVID-19 infection in China and its impact on India4
Pk Pd and antibiotic of choice4
Letter to the editor4
Rational test selection in immunology laboratory: Investigating the utility of repeated antinuclear antibody tests4
Minimum inhibitory concentration of doxycycline for Vibrio parahaemolyticus4
Antimicrobial resistance in genital Mycoplasmas infections4
Tn5406, a staphylococcal transposon associated with macrolide-lincosamide-streptograminb resistance in clinical isolates of Staphylococcus aureus4
Aims and Scope4
Delayed identification of treatment failure causes high levels of acquired drug resistance and less future drug options among HIV-1-infected South Indians4
Brain abscess caused by Scedosporium boydii in a systemic lupus erythematosus patient: A case report and literature review4
Impact of improving infection control and antibiotic stewardship practices on nosocomial infections and antimicrobial resistance in an oncology centre from India4
Salmonella enterica serovar Give causing brain abscess and bacteremia: A case report4
Invasive Corynebacterium striatum infection: A case of concurrent isolation from blood and cerebrospinal fluid4
Unveiling the uncommon: A rare case report of osteomyelitis caused by Enterococcus avium4
Diagnosis of Ureaplasma parvum meningitis by mNGS in an extremely low birth weight infant with multi-system lesions4
‘Effectiveness of various sulbactam-based combination antibiotic therapy in the management of ventilator-associated pneumonia caused by carbapenem-resistant Acinetobacter baumannii in a tertiary care 4
Risk factors and clinical outcomes in patients with colistin-resistant Klebsiella pneumoniae bloodstream infection: A retrospective analysis4
Aeromonas dhakensis - A red alert in blood cultures!4
Community Acquired Sphingomonas paucimobilis: Instigator or an Innocent Bystander4
Clinico-microbiological profile of Burkholderia pseudomallei infections in a tertiary care hospital in South India4
Carbapenem resistance in Enterobacterales: Predicting clinical outcomes in bloodstream infections4
Burden of biocide resistance among multidrug-resistant bacteria isolated from various clinical specimens in a tertiary care hospital4
Evaluation of T and B cell immunophenotyping and antibody response to Covid-19 vaccine: Comment4
Musculoskeletal melioidosis-a retrospective review of 22 cases from a tertiary care centre in South Tamilnadu4
Impact of conducting hand hygiene audit in COVID-19 care locations of India—A large scale national multicentric study – HHAC study4
Editorial Board4
HPV vaccines – A game changer for preventing HPV-related cancers4
Rapid identification of carbapenemases and in vitro synergy testing of ceftazidime-avibactam with aztreonam in extensively drug-resistant gram-negative pathogens: Establishing the realm of promise4
Seroprevalence of spotted fever group rickettsiosis in Kashmir: A community-based study using indirect immunofluorescence assay4
Threat of monkeypox: Correspondence4
Aquatic whispers: Decoding skin manifestation of Aeromonas hydrophila4
Serial active surveillance cultures of children admitted to a medical pediatric intensive care unit of a tertiary care teaching hospital: A prospective observational study4
Pertussis in India: Vaccine-driven evolution, waning immunity, and the urgent need for Tdap boosters4
First autochthonous case of cutaneous leishmaniasis from Gujarat—a non-endemic area in India3
Evaluation of in-vitro colistin susceptibility and clinical profile of carbapenem resistant Enterobacteriaceae related invasive infections3
Indian microbiology EQAS registered laboratory’s capacity building and infection control practices during the COVID-19 pandemic in India: Lessons learnt and gaps identified3
In-vitro efficacy of levonadifloxacin against methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates3
Targeted Next Generation Sequencing (tNGS) for detection of drug-resistant tuberculous meningitis: Is this sequencing technology ready for prime time?3
Outbreak investigation of Dengue like fever in rural area of Rajasthan3
False positivity of cryptococcal LFA: A diagnostic challenge3
Molecular characterization of methicillin-resistant Staphylococcus aureus: Dissemination of multidrug-resistant community-associated MRSA and emergence of LA-MRSA, in a healthcare setting3
Out of Sight, Should not be out of mind: A perplexing case of Malaria3
Disseminated cerebral cryptococcoma mimicking glioblastoma - A case report.”3
Neutralizing antibody responses to SARS-CoV-2: A population based seroepidemiological analysis3
A retrospective evaluation of recently introduced EUCAST rapid antimicrobial susceptibility testing (RAST) breakpoints for Salmonella enterica in a high burden setting3
Molecular characterization of coxsackievirus A24 variants isolated from an outbreak of acute hemorrhagic conjunctivitis3
New design and optimization of an in-house quantitative TaqMan Real-Time PCR-based assay for the detection and monitoring of occult hepatitis B virus (genotype A-J) infection3
Defining drug resistance beyond rifampicin: use of Xpert® MTB/XDR assay in tuberculous meningitis3
Performance of Cepheid CT/NG Xpert rapid PCR test for detection of Chlamydia trachomatis and Neisseria gonorrhoeae at a tertiary care centre in North India3
Fever in the returning traveler3
Unveiling misidentified Staphylococcus argenteus in clinical infections: Findings from a tertiary hospital in Karnataka3
Aims and Scope3
Diptheroids can cause nosocomial UTI and be multidrug resistant: A case report of Corynebacterium striatum, first from India3
Identification of Enterocytozoon bieneusi in an HIV-negative bronchiectasis patient with respiratory infection based on metagenomic next-generation sequencing: A case report3
Whole-genome sequence analysis of cefiderocol-resistant E. coli and Klebsiella pneumoniae isolates from cefiderocol treatment-naïve patients3
Advancing beyond conventional vaccines: The potential of next-generation vaccines in combatting antibiotic-resistant bacteria3
Acute post-operative panophthalmitis by Nocardia otitidiscaviarum: A rare presentation3
Commonly associated aerobic microbial pathogens and their antibiotic susceptibility profile in diabetic foot ulcers in tertiary care centre in Western Maharashtra3
Antimicrobial resistance in blood culture proven sepsis in outborn and inborn neonates3
Species identification and antifungal susceptibility pattern of oral Candida isolates in pemphigus vulgaris: results from a case-control study3
Macrolides versus other antibiotics in pediatric scrub typhus: A meta-analysis3
Fatal case of Leptospira wolffii infection in Sikkim, India: An autochthonous case from a new geographical region3
Three waves, three vaccines, three COVID-19 infections - Saga of a frontline health care worker during the pandemic3
The importance of stool antigen test in the diagnosis and management of Helicobacter pylori infections3
The enigmatic voyage of pneumococcal carriage: Unraveling the risk factors in pediatric populations -- A scoping review3
Papulaspora equi keratitis in an infant3
Unmasking a looming crisis: Escalating MIC of last resort drugs against MRSA isolates from a tertiary care hospital in Central India3
Effect of delay in processing and storage temperature on diagnosis of SARS-CoV-2 by RTPCR testing3
Candida glabrata associated primary pleuro-pulmonary infections: A report of two cases3
Invasive aspergillosis in a child without any identifiable risk factors3
Effectiveness of sample pooling strategies for diagnosis of SARS-CoV-2: Specimen pooling vs. RNA elutes pooling3
Recurrent sternal wound infection caused by Gordonia bronchialis after open heart surgery3
Malaria a culprit of Gullian Barre Syndrome (GBS): A case report3
Evaluation of phenotypic assays for the detection of penicillinase-producing Staphylococcus aureus in clinical laboratories3
Outbreak of leptospirosis caused by Leptospira wolffii with HAV coinfections in lower Assam, Northeast India in 2024: Clinical impact and public health implications3
Sputnik V vaccine-related complications and its impression on inflammatory biomarkers in healthcare providers3
Approach towards surveillance-based diagnosis of acute respiratory illness in India: Expert recommendations3
Hepatosplenic abscess due to Burkholderia pseudomallei-a retrospective review of nineteen cases from a tertiary care centre in South India3
Rhino-orbito-cerebral mucormycosis during Covid-19 pandemic- a prospective observational study3
Concordance of dengue viral load with disease severity and different clinical manifestations: A systematic review and meta-analysis3
Approach to fever in children3
Diagnostic accuracy of truenat MTB plus for the detection of pulmonary and extrapulmonary tuberculosis3
Presence of diarrhea associated with better outcomes in patients with COVID-19 – A prospective evaluation3
A retrospective analysis on seroprevalence of acute viral hepatitis observed among dengue patients attending a tertiary care centre in central India3
Editorial Board3
In-vitro susceptibility of cefiderocol and other comparators in carbapenem-resistant Gram-negative bacilli: A study from India3
Analysing the clinical knowledge of ChatGPT in medical microbiology in the undergraduate medical examination3
A rising threat: Emergence of Listeria monocytogenes infection from hilly terrain of North India2
Whole genome sequencing for the prediction of resistant tuberculosis strains from northern India2
Table of Contents2
Burkholderia cepacia infections at sites other than the respiratory tract: A large case series from a tertiary hospital in Madurai2
Human Bocavirus infection in childhood acute respiratory infection: Is it an innocent bystander?2
Genetic characterization of Toxoplasma gondii strains isolated from humans living in İzmir, Türkiye2
Prevalence of faecal carriage of Carbapenemase Producing Enterobacteriaceae in healthy Indian subjects from the community2
Molecular and genomic characterization of Leptospira isolates in humans and its relation to disease severity2
Brucellosis in pyrexia of unknown origin: Reminiscing the forgotten entity2
Expanding geographical niche of emerging pathogen Fonsecaea nubica: First report of its isolation from India from a case of chromoblastomycosis2
Table of Contents2
Influenza virus and its subtypes circulating during 2018–2019: A hospital-based study from Assam2
First case report of recurrent cervical lymphadenopathy due to Chordomyces antarcticum2
Autoimmune encephalitis: A diagnostic enigma2
Subcutaneous phaeohyphomycosis due to a rare fungus Parathyridaria percutanea: First reported case from central India2
Uncommon non-fermentative gram-negative superbugs - A surge in bacteraemia patients at an apex super speciality hospital2
Table of Contents2
Paeniclostridium sordellii causing liver abscess: A rare case report in India2
Table of Contents2
Silent escalation: The journey of Shigella from gut to blood2
Sputnik V vaccine-related complications and inflammatory biomarkers: Correspondence2
Haemophilus influenzae bacteremia: A 5-year (2016–2020) retrospective study analysing the clinical and laboratory features2
Difficult-to-treat resistant gram-negative blood stream infections – the beginning of a superbug era – a prospective observational study2
Bloodstream infection caused by Solobacteriummoorei: A case report and literature review2
Burkholderia vietnamiensis infection in a haematological unit: Case series and review of literature of this new emerging pathogen2
Seasonal and geographic variation of environmental burden of dematiaceous fungi in North India2
Genomic characterization of Terrisporobacter glycolicus from a case of monomicrobial gas gangrene2
Automating Microbial Community Analysis (AMCA): Development and application of an amplicon based graphical pipeline in patients with Chronic Kidney Disease2
Molecular analysis of acute hemorrhagic conjunctivitis in a tertiary care hospital, Kalburgi district, Karnataka 20232
Ceftriaxone-resistant Salmonella Typhi isolated from paediatric patients in north India: Insights into genetic profiles and antibiotic resistance mechanisms2
Table of Contents2
Study of the association of Burkholderia pseudomallei lipopolysaccharide genotypes and variable virulence factors with different clinical manifestations of melioidosis2
Burkholderia cepacia complex as a cause of community acquired bacteremia in a young immuncompetent male2
FIA (fluorescent immunoassay) test in Dengue2
Inconsolable crying in osseous congenital syphilis: Sisto sign2
Table of Contents2
Microsphaeropsis arundinis: a coelomycetes and an emerging cause of human phaeohyphomycosis reported from Assam, India with review of the literature2
Occult hepatitis B virus infection among chronic liver disease patients: Insights from a tertiary care hospital2
Management of infections caused by Extended-spectrum beta-lactamase-producing Enterobacterales in Indian patients2
Indian association of medical microbiologists (IAMM) position paper on guidelines for COVID and SARSCoV2 infections2
Fulminant Pneumocystis jirovecii pneumonia presenting as multi-organ dysfunction syndrome in an immunocompetent host2
Faster and accurate identification of clinically important Trichosporon using MALDI TOF MS2
Microbiology: Foundational science of modern medicine2
Evaluation of the presence of integrons, sul and smqnr genes and the prevalence of antibiotic resistance in Stenotrophomonas maltophilia clinical isolates2
Eight year study on evolution of antimicrobial resistance in an antimicrobial-naïve trauma population2
Current perspective of adrenal histoplasmosis in India: A prospective study in a tertiary care hospital, Eastern India2
Corrigendum to ‘Molecular epidemiology of hand, foot, and mouth disease in Karnataka, India in 2022’ [Indian J Med Microbiol 46 (2023) 100429]2
Pulmonary cryptococcosis in chronic kidney disease2
Acanthamoeba species from a post-covid patient with CSF rhinorrhea; a next possible post covid menace? A case report2
Accelerating pneumococcal protection in India: The case for rapid adoption of PCV20 across pediatric and adult populations2
Accuracy of various matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS)-based rapid identification methods—As a tool to augment diagnostic stewardship in blood 2
Microbial cell-free DNA detection: Minimally invasive diagnosis of infectious diseases2
An insight into whole genome sequencing data of methicillin-resistant Staphylococcus aureus circulating in a teaching hospital in North India2
Molecular characterization of Carbapenem resistant Enterobacterales causing blood stream infections in critically ill patients2
Early prosthetic valve endocarditis due to Kytococcus schroeteri – A case report and review of literature2
Peritoneal dialysis-associated peritonitis caused by Neisseria.sicca: A case report and literature review2
Epidemiological, clinical and genetic characterization of scrub typhus in patients presenting with acute febrile illness in New Delhi2
Comparison of B1 and RE 529 gene targets by real time PCR and LAMP assay for diagnosis of toxoplasmosis in pregnant females2
Diagnostic utility and performance of rapid antigen test in SARS CoV- 2 in symptomatic and asymptomatic patients during the second pandemic wave in Kashmir, North India2
Invasive pulmonary aspergillosis (IPA)- A study of risk factors, diagnostic modalities and role of galactomannan antigen detection2
Clinical implications of revised piperacillin-tazobactam breakpoints in CLSI M-100 S322
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