Archives of Pharmacal Research

Papers
(The TQCC of Archives of Pharmacal Research is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Mouse models of nonalcoholic steatohepatitis and their application to new drug development280
Evaluation of bone health and fracture risk in type 2 diabetes: a network meta-analysis of anti-diabetic treatments versus placebo111
Recent paclitaxel formulation strategies: expanding the therapeutic index by addressing biopharmaceutical and toxicity limitations93
Continuous TNF-α exposure in mammary epithelial cells promotes cancer phenotype acquisition via EGFR/TNFR2 activation90
Antibody drug conjugates as targeted cancer therapy: past development, present challenges and future opportunities83
Osteogenic effect of an adiponectin-derived short peptide that rebalances bone remodeling: a potential disease-modifying approach for postmenopausal osteoporosis therapy66
Anti-fibrotic effect of aurocyanide, the active metabolite of auranofin63
Cinnamic acid attenuates Klebsiella pneumoniae virulence by suppressing capsule biosynthesis63
Correction to: The multifaceted role of STAT3 pathway and its implication as a potential therapeutic target in oral cancer63
Impact of binge drinking on alcoholic liver disease62
Myriocin suppresses tumor growth by modulating macrophage polarization and function through the PI3K/Akt/mTOR pathway51
PBPK modeling of the antidepressant doxepin incorporating CYP2D6 genotype for precision pharmacotherapy48
Germacrane and humulane sesquiterpenes from the roots and rhizomes of Valeriana officinalis var. latifolia and their anti-inflammatory and anti-influenza virus activities46
Retraction Note: Anti-inflammatory effect of atorvastatin on vascular reactivity and insulin resistance in fructose fed rats45
Regulation of NOX/p38 MAPK/PPARα pathways and miR-155 expression by boswellic acids reduces hepatic injury in experimentally-induced alcoholic liver disease mouse model: novel mechanistic insight44
Challenges and opportunities of developing small-molecule therapies for age-related macular degeneration42
Antibody-drug conjugates in cancer therapy: innovations, challenges, and future directions42
Prenylated flavonoid fractions from Glycyrrhiza glabra alleviate insulin resistance in HepG2 cells by regulating the ERK/IRS-1 and PI3K/Akt signaling pathways38
Donepezil improves skeletal muscle insulin resistance in obese mice via the AMPK/FGF21-mediated suppression of inflammation and ferroptosis37
Isolation, structure elucidation, total synthesis, and biosynthesis of dermazolium A, an antibacterial imidazolium metabolite of a vaginal bacterium Dermabacter vaginalis36
Minor structural changes, major functional impacts: posttranslational modifications and drug targets35
Recent advances on Pestalotiopsis genus: chemistry, biological activities, structure–activity relationship, and biosynthesis33
The role and application of transcriptional repressors in cancer treatment33
Non-alcoholic fatty liver disease and liver secretome33
Naringin promotes fat browning mediated by UCP1 activation via the AMPK signaling pathway in 3T3-L1 adipocytes31
A review on bacteria-derived antioxidant metabolites: their production, purification, characterization, potential applications, and limitations31
Effects of fluconazole on the pharmacokinetics of celecoxib and its carboxylic acid metabolite in different CYP2C9 genotypes30
Tirzepatide mitigates atherosclerosis progression and modulates oxLDL-mediated proatherogenic effects in macrophages: evidence for M1/M2 homeostasis restoration29
Tumor microenvironment regulation by reactive oxygen species-mediated inflammasome activation28
Vitamin D remodels the tumor microenvironment to suppress gastric cancer progression through cancer-associated fibroblasts-secreted exosomal miR-378c targeting KDSR27
Anti-osteoporosis effects of triterpenoids from the fruit of sea buckthorn (Hippophae rhamnoides) through the promotion of osteoblast differentiation in mesenchymal stem cells, C3H10T1/227
The inhibition of endothelial DLL4-NOTCH1 signaling by 2'-hydroxyflavanone enhances anti-PD-1 therapy in melanoma27
Cell membrane chromatography relative competitive method for the accurate determination of relative KD values of drug-receptor interactions26
Salvianolic acid A enhances Treg accumulation via the RUNX1/CBFβ/FOXP3 axis as a neuroprotective immunomodulator in ischemic stroke24
Dapagliflozin attenuates myocardial remodeling in hypertension by activating the circadian rhythm signaling pathway24
Phytochemistry and pharmacology of plants in the genus Chaenomeles24
Nanostructured branched Y-DNA promotes antitumor immunity through dual activation of cGAS/STING and TLR924
Predictive biomarkers for molecularly targeted therapies and immunotherapies in breast cancer23
Potential effects of a human milk oligosaccharide 6′-sialyllactose on angiotensin II-induced aortic aneurysm via p90RSK/TGF-β/SMAD2 signaling pathway22
Immunosenescence and age-related immune cells: causes of age-related diseases22
Cathepsin B maturation plays a critical role in leptin-induced hepatic cancer cell growth through activation of NLRP3 inflammasomes21
Ischemic stroke neuroprotection revisited: translational barriers and a phase-resolved, biomarker-anchored framework21
Potential of natural products in inflammation: biological activities, structure–activity relationships, and mechanistic targets21
Effects of CYP2C9 and CYP2C19 genetic polymorphisms on the pharmacokinetics and pharmacodynamics of gliclazide in healthy subjects21
Paeonia genus: a systematic review of active ingredients, pharmacological effects and mechanisms, and clinical applications for the treatment of cancer20
Akt-activated GSK3β inhibitory peptide effectively blocks tau hyperphosphorylation20
Antibacterial properties of natural products from marine fungi reported between 2012 and 2023: a review19
New tricyclic systems as photosensitizers towards triple negative breast cancer cells19
Natural compounds targeting inflammatory signaling and cell adhesion molecules in ischemic acute kidney injury17
Advances and challenges of estrogen receptor-targeted agents in breast cancer17
Effects of CYP2D6 and CYP2C19 genetic polymorphisms and cigarette smoking on the pharmacokinetics of tolperisone17
Inhibition of autophagy with chloroquine dysregulates mitochondrial quality control and energetics in adipocytes16
Biodegradable gelatin methacryloyl microneedles: a new paradigm in transdermal drug delivery16
Homoharringtonine inhibits growth and migration in non-small cell lung cancer via PDIA4-mediated modulation of autophagy and EMT16
Cardiotoxicity linked to anticancer agents and cardioprotective strategy16
Mechanistic insights and emerging therapeutic strategies targeting endothelial dysfunction in cardiovascular diseases15
Selumetinib overcomes gefitinib primary and acquired resistance by regulating MIG6/STAT3 in NSCLC15
Advanced therapeutic strategies targeting microglia: beyond neuroinflammation15
Activation of cryptic biosynthetic pathways in Saccharopolyspora spinosa through deletion of the spinosyn gene cluster: induction of cryptic and bioactive natural products15
Advances in sarcopenia: mechanisms, therapeutic targets, and intervention strategies15
PF protects retinal pigment epithelial cells from oxidative injury by enhancing mitophagy through a CUL3-dependent AMPK/ULK1 pathway15
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