OOIR: Observatory of International Research

Papers

(The TQCC of Archives of Pharmacal Research is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Effects of CYP2D6*10 allele on the pharmacokinetics of tolperisone	116
Physiologically based pharmacokinetic modelling to predict the pharmacokinetics of metoprolol in different CYP2D6 genotypes	107
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells	84
Complicity of α-synuclein oligomer and calcium dyshomeostasis in selective neuronal vulnerability in Lewy body disease	83
Human milk oligosaccharides 3′-sialyllactose and 6′-sialyllactose attenuate LPS-induced lung injury by inhibiting STAT1 and NF-κB signaling pathways	81
Amyloidogenic, neuroinflammatory and memory dysfunction effects of HIV-1 gp120	54
Dual roles of myeloid-derived suppressor cells in various diseases: a review	51
Exploring new histone deacetylase 6 inhibitors and their effects on reversing the α-tubulin deacetylation and cell morphology changes caused by methamphetamine	41
Mouse models of nonalcoholic steatohepatitis and their application to new drug development	38
Inhibition of PI3K/mTOR/KATP channel blunts sodium thiosulphate preconditioning mediated cardioprotection against ischemia–reperfusion injury	37
Interplay between YAP/TAZ and metabolic dysfunction-associated steatotic liver disease progression	36
Is loss of smell an early predictor of COVID-19 severity: a systematic review and meta-analysis	35
Ginkwanghols A and B, osteogenic coumaric acid-aliphatic alcohol hybrids from the leaves of Ginkgo biloba	35
Renal tubular PAR2 promotes interstitial fibrosis by increasing inflammatory responses and EMT process	35
Combination therapy involving HSP90 inhibitors for combating cancer: an overview of clinical and preclinical progress	34
The role of mucosal barriers in human gut health	33
Ginsenoside-Rg2 exerts anti-cancer effects through ROS-mediated AMPK activation associated mitochondrial damage and oxidation in MCF-7 cells	32
Distinctive role of inflammation in tissue repair and regeneration	32
Atractylenolides (I, II, and III): a review of their pharmacology and pharmacokinetics	31
Androgen receptor and hyaluronan-mediated motility receptor as new molecular targets of baicalein: new molecular mechanisms for its anticancer properties	31
Phytochemistry and pharmacology of plants in the genus Chaenomeles	31
CD48-expressing non-small-cell lung cancer cells are susceptible to natural killer cell–mediated cytotoxicity	28
Biological insights and therapeutic potential of Glycyrrhiza uralensis and its bioactive compounds: an updated review	27
Recent advances in CRISPR technologies for genome editing	27
Review on pharmacological effects of gastrodin	27

Tumor lactic acid: a potential target for cancer therapy	26
Ginsenoside Rg3 activates the immune function of CD8+ T cells via circFOXP1-miR-4477a-PD-L1 axis to induce ferroptosis in gallbladder cancer	26
Cell membrane chromatography relative competitive method for the accurate determination of relative KD values of drug-receptor interactions	25
Physiologically based pharmacokinetic (PBPK) modeling to predict the pharmacokinetics of irbesartan in different CYP2C9 genotypes	24
Pralsetinib: chemical and therapeutic development with FDA authorization for the management of RET fusion-positive non-small-cell lung cancers	23
Dihydroartemisinin inhibits follicular helper T and B cells: implications for systemic lupus erythematosus treatment	22
E3 ubiquitin ligase RNF180 mediates the ALKBH5/SMARCA5 axis to promote colon inflammation and Th17/Treg imbalance in ulcerative colitis mice	22
Artemongolins A–K, undescribed germacrane-guaiane sesquiterpenoid dimers from Artemisia mongolica and their antihepatoma activities	22
Adapalene induces adipose browning through the RARβ-p38 MAPK-ATF2 pathway	21
COVID-19 and pulmonary fibrosis: therapeutics in clinical trials, repurposing, and potential development	21
Engineered fibrotic liver-targeted truncated transforming growth factor β receptor type II variant for superior anti-liver fibrosis therapy	20
Discovery and synthesis of 1,2,4-oxadiazole derivatives as novel inhibitors of Zika, dengue, Japanese encephalitis, and classical swine fever virus infections	20
Immunosenescence and age-related immune cells: causes of age-related diseases	20
Stabilization of RNA G-quadruplexes in the SARS-CoV-2 genome inhibits viral infection via translational suppression	20
Osteogenic effect of an adiponectin-derived short peptide that rebalances bone remodeling: a potential disease-modifying approach for postmenopausal osteoporosis therapy	20
The potential of therapeutic strategies targeting mitochondrial biogenesis for the treatment of insulin resistance and type 2 diabetes mellitus	19
Inhibitory effects of 6′-sialyllactose on angiotensin II-induced proliferation, migration, and osteogenic switching in vascular smooth muscle cells	19
Arsenic trioxide: applications, mechanisms of action, toxicity and rescue strategies to date	18
Paeoniflorin increases the survival of Pseudomonas aeruginosa infected Caenorhabditis elegans at the immunosuppression stage by activating PMK-1, BAR-1, and EGL-1 signals	18
Continuous TNF-α exposure in mammary epithelial cells promotes cancer phenotype acquisition via EGFR/TNFR2 activation	18
Astragali Radix: comprehensive review of its botany, phytochemistry, pharmacology and clinical application	18
PBPK modeling to predict the pharmacokinetics of venlafaxine and its active metabolite in different CYP2D6 genotypes and drug–drug interactions with clarithromycin and paroxetine	18
The effects of BRL-50481 on ovalbumin-induced asthmatic lung inflammation exacerbated by co-exposure to Asian sand dust in the murine model	17
Potential biological functions and future perspectives of sialylated milk oligosaccharides	17
Comparative metabolism of aschantin in human and animal hepatocytes	17
The novel psychoactive substance 25E-NBOMe induces reward-related behaviors via dopamine D1 receptor signaling in male rodents	17
PBPK modeling to predict the pharmacokinetics of pantoprazole in different CYP2C19 genotypes	16
Dapagliflozin attenuates myocardial remodeling in hypertension by activating the circadian rhythm signaling pathway	16
EGF, a veteran of wound healing: highlights on its mode of action, clinical applications with focus on wound treatment, and recent drug delivery strategies	16
Predictive biomarkers for molecularly targeted therapies and immunotherapies in breast cancer	15
Antibody–drug conjugates and bispecific antibodies targeting cancers: applications of click chemistry	15
Isoindolin-1-ones from the stems of Nicotiana tabacum and their antiviral activities	15
Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives	15
Phytochemistry and pharmacology of natural prenylated flavonoids	15
Understanding of sarcopenia: from definition to therapeutic strategies	15