Archives of Pharmacal Research

Papers
(The median citation count of Archives of Pharmacal Research is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Ubiquitin–proteasome system (UPS) as a target for anticancer treatment208
Phytochemistry and pharmacological activity of the genus artemisia99
Pathological angiogenesis and inflammation in tissues89
Astragalus polysaccharide: a review of its immunomodulatory effect87
Biomedical features and therapeutic potential of rosmarinic acid84
Mechanisms of resistance to chemotherapy in non-small cell lung cancer77
Aldose Reductase: a cause and a potential target for the treatment of diabetic complications74
Skin barrier dysfunction and filaggrin69
Therapeutic regulation of the NLRP3 inflammasome in chronic inflammatory diseases69
Pharmacological effects of harmine and its derivatives: a review68
Understanding of sarcopenia: from definition to therapeutic strategies54
Overview of COVID-19 inflammatory pathogenesis from the therapeutic perspective54
Phytochemical and pharmacological properties of Myristica fragrans Houtt.: an updated review47
Crosstalk between angiogenesis and immune regulation in the tumor microenvironment46
Biological roles of cytochrome P450 1A1, 1A2, and 1B1 enzymes43
Ginkwanghols A and B, osteogenic coumaric acid-aliphatic alcohol hybrids from the leaves of Ginkgo biloba41
Flavonoids as therapeutic candidates for emotional disorders such as anxiety and depression38
The role of mucosal barriers in human gut health38
Role of specialized pro-resolving lipid mediators and their receptors in virus infection: a promising therapeutic strategy for SARS-CoV-2 cytokine storm37
mRNA vaccines: the most recent clinical applications of synthetic mRNA37
Recent advances in the pathology of prodromal non-motor symptoms olfactory deficit and depression in Parkinson’s disease: clues to early diagnosis and effective treatment36
Role of mitochondrial dynamics and mitophagy of vascular smooth muscle cell proliferation and migration in progression of atherosclerosis35
The role of epithelial–mesenchymal transition-regulating transcription factors in anti-cancer drug resistance35
Ginsenoside-Rg2 exerts anti-cancer effects through ROS-mediated AMPK activation associated mitochondrial damage and oxidation in MCF-7 cells34
Protective effects of ginsenoside-Rg2 and -Rh1 on liver function through inhibiting TAK1 and STAT3-mediated inflammatory activity and Nrf2/ARE-mediated antioxidant signaling pathway33
Atractylenolides (I, II, and III): a review of their pharmacology and pharmacokinetics32
Fibroblast growth factor 2 exacerbates inflammation in adipocytes through NLRP3 inflammasome activation31
Recent advances in selective and targeted drug/gene delivery systems using cell-penetrating peptides31
Latest research progress on anticancer effect of baicalin and its aglycone baicalein31
Is loss of smell an early predictor of COVID-19 severity: a systematic review and meta-analysis30
Pharmacokinetics of ginsenosides following repeated oral administration of red ginseng extract significantly differ between species of experimental animals29
New phenalenone derivatives from the Hawaiian volcanic soil-associated fungus Penicillium herquei FT729 and their inhibitory effects on indoleamine 2,3-dioxygenase 1 (IDO1)29
Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives28
β-Sitosterol attenuates liver injury in a rat model of chronic alcohol intake28
LncRNA AIRN influences the proliferation and apoptosis of hepatocellular carcinoma cells by regulating STAT1 ubiquitination27
Effects of CYP2D6 genetic polymorphism on the pharmacokinetics of metoclopramide27
Antibody–drug conjugates and bispecific antibodies targeting cancers: applications of click chemistry27
Physiologically based pharmacokinetic (PBPK) modeling for prediction of celecoxib pharmacokinetics according to CYP2C9 genetic polymorphism26
The multifaceted role of NRF2 in cancer progression and cancer stem cells maintenance26
Review on pharmacological effects of gastrodin26
Kaempferol sensitizes cell proliferation inhibition in oxaliplatin-resistant colon cancer cells25
Comparative evaluation of bioactive phytochemicals in Spinacia oleracea cultivated under greenhouse and open field conditions24
Phytochemistry and pharmacology of natural prenylated flavonoids24
ABCB1 c.2677G>T/c.3435C>T diplotype increases the early-phase oral absorption of losartan22
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells22
Targeting fatty acid metabolism for fibrotic disorders22
NRF2 level is negatively correlated with TGF-β1-induced lung cancer motility and migration via NOX4-ROS signaling22
Function and therapeutic development of exosomes for cancer therapy22
Recent progresses in marine microbial-derived antiviral natural products21
Recent progress in development and applications of second near‐infrared (NIR-II) nanoprobes21
Blood-brain barrier dysfunction as a potential therapeutic target for neurodegenerative disorders20
Antibody drug conjugates as targeted cancer therapy: past development, present challenges and future opportunities20
Mechanistic diversity involved in the desensitization of G protein-coupled receptors20
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway20
Alcoholic liver disease: a new insight into the pathogenesis of liver disease19
New tricyclic systems as photosensitizers towards triple negative breast cancer cells19
Empagliflozin mitigates type 2 diabetes-associated peripheral neuropathy: a glucose-independent effect through AMPK signaling18
Peroxisome proliferator-activated receptor gamma: a novel therapeutic target for cognitive impairment and mood disorders that functions via the regulation of adult neurogenesis18
Therapeutic effects of histone deacetylase inhibitors on heart disease18
Triterpenoids from Dysoxylum genus and their biological activities18
Exosomal microRNAs as diagnostic and therapeutic biomarkers in non-malignant liver diseases18
Physiologically based pharmacokinetic (PBPK) modeling of meloxicam in different CYP2C9 genotypes18
Isoindolin-1-ones from the stems of Nicotiana tabacum and their antiviral activities18
Pharmacology and adverse effects of new psychoactive substances: synthetic cannabinoid receptor agonists17
Naringin promotes fat browning mediated by UCP1 activation via the AMPK signaling pathway in 3T3-L1 adipocytes17
Paeoniflorin increases the survival of Pseudomonas aeruginosa infected Caenorhabditis elegans at the immunosuppression stage by activating PMK-1, BAR-1, and EGL-1 signals17
Ginsenoside Rh1 inhibits tumor growth in MDA-MB-231 breast cancer cells via mitochondrial ROS and ER stress-mediated signaling pathway16
COVID-19 and pulmonary fibrosis: therapeutics in clinical trials, repurposing, and potential development16
Scope and challenges of nanoparticle-based mRNA delivery in cancer treatment16
CD48-expressing non-small-cell lung cancer cells are susceptible to natural killer cell–mediated cytotoxicity16
Effects of paroxetine on the pharmacokinetics of atomoxetine and its metabolites in different CYP2D6 genotypes15
Physiologically based pharmacokinetic modeling of candesartan related to CYP2C9 genetic polymorphism in adult and pediatric patients15
Protein tyrosine phosphatases (PTPs) in diabetes: causes and therapeutic opportunities15
Phytochemicals against anti‐diabetic complications: targeting the advanced glycation end product signaling pathway15
Advances in plant-derived natural products for antitumor immunotherapy15
Sestrin2 induction contributes to anti-inflammatory responses and cell survival by globular adiponectin in macrophages15
Treatments of inflammatory bowel disease toward personalized medicine15
Physiologically based pharmacokinetic (PBPK) modeling of piroxicam with regard to CYP2C9 genetic polymorphism14
Activation of β2 adrenergic receptor signaling modulates inflammation: a target limiting the progression of kidney diseases14
Ubiquitin–proteasome system as a target for anticancer treatment—an update14
Effects of CYP2C9*3 and *13 alleles on the pharmacokinetics and pharmacodynamics of glipizide in healthy Korean subjects14
Physiologically based pharmacokinetic (PBPK) modelling of tamsulosin related to CYP2D6*10 allele14
Distinctive role of inflammation in tissue repair and regeneration14
The essential role of TAZ in normal tissue homeostasis13
EGF, a veteran of wound healing: highlights on its mode of action, clinical applications with focus on wound treatment, and recent drug delivery strategies13
Molecular epigenetic dynamics in breast carcinogenesis13
Regulatory roles of G-protein coupled receptors in adipose tissue metabolism and their therapeutic potential13
Tumor lactic acid: a potential target for cancer therapy13
Anti-angiogenesis revisited: reshaping the treatment landscape of advanced non-small cell lung cancer13
Clerodane furanoditerpenoids from the stems of Tinospora sinensis13
ACY-241, an HDAC6 inhibitor, overcomes erlotinib resistance in human pancreatic cancer cells by inducing autophagy13
Renal tubular PAR2 promotes interstitial fibrosis by increasing inflammatory responses and EMT process13
Trehalose ameliorates prodromal non-motor deficits and aberrant protein accumulation in a rotenone-induced mouse model of Parkinson’s disease12
Methamphetamine-induced dopaminergic neurotoxicity as a model of Parkinson’s disease11
Bioactive natural products from the genus Salinospora: a review11
Anti-neuroinflammatory effect of oxaline, isorhodoptilometrin, and 5-hydroxy-7-(2′-hydroxypropyl)-2-methyl-chromone obtained from the marine fungal strain Penicillium oxalicum CLC-MF0511
Aspergillus co-cultures: A recent insight into their secondary metabolites and microbial interactions11
Effects of phytoestrogens on reproductive organ health10
Overexpressing microRNA-203 alleviates myocardial infarction via interacting with long non-coding RNA MIAT and mitochondrial coupling factor 610
Diacerein counteracts acetaminophen-induced hepatotoxicity in mice via targeting NLRP3/caspase-1/IL-1β and IL-4/MCP-1 signaling pathways10
Development of JAK inhibitors for the treatment of immune-mediated diseases: kinase-targeted inhibitors and pseudokinase-targeted inhibitors10
Canonical transient receptor potential channels and their modulators: biology, pharmacology and therapeutic potentials10
Structural feature of TRAFs, their related human diseases and therapeutic intervention10
PBN inhibits a detrimental effect of methamphetamine on brain endothelial cells by alleviating the generation of reactive oxygen species10
Isolation, structure elucidation, total synthesis, and biosynthesis of dermazolium A, an antibacterial imidazolium metabolite of a vaginal bacterium Dermabacter vaginalis9
Advances in liver organoids: model systems for liver disease9
The multifaceted role of STAT3 pathway and its implication as a potential therapeutic target in oral cancer9
miR-139-5p promotes neovascularization in diabetic retinopathy by regulating the phosphatase and tensin homolog9
6′-Sialylactose abolished lipopolysaccharide-induced inflammation and hyper-permeability in endothelial cells9
Physiologically based pharmacokinetic modelling to predict the pharmacokinetics of metoprolol in different CYP2D6 genotypes9
Protective effect of lncRNA CRNDE on myocardial cell apoptosis in heart failure by regulating HMGB1 cytoplasm translocation through PARP-19
The function, mechanisms, and clinical applications of metformin: potential drug, unlimited potentials9
New insights into the role of the Golgi apparatus in the pathogenesis and therapeutics of human diseases9
IL-1 and CD40/CD40L platelet complex: elements of induction of Crohn’s disease and new therapeutic targets9
Enhanced bioavailability and hepatoprotective effect of silymarin by preparing silymarin-loaded solid dispersion formulation using freeze-drying method9
Anti-osteoporosis effects of triterpenoids from the fruit of sea buckthorn (Hippophae rhamnoides) through the promotion of osteoblast differentiation in mesenchymal stem cells, C3H10T1/28
Protection of the hematopoietic system against radiation-induced damage: drugs, mechanisms, and developments8
The effects of BRL-50481 on ovalbumin-induced asthmatic lung inflammation exacerbated by co-exposure to Asian sand dust in the murine model8
Recent advances in CRISPR technologies for genome editing8
Beyond DNA sensing: expanding the role of cGAS/STING in immunity and diseases8
Physiologically based pharmacokinetic (PBPK) modeling of flurbiprofen in different CYP2C9 genotypes8
Effects of CYP2C19 genetic polymorphism on the pharmacokinetics of tolperisone in healthy subjects8
Discovery and synthesis of 1,2,4-oxadiazole derivatives as novel inhibitors of Zika, dengue, Japanese encephalitis, and classical swine fever virus infections8
Inhibition of hyaluronan synthesis by 4-methylumbelliferone ameliorates non-alcoholic steatohepatitis in choline-deficient l-amino acid-defined diet-induced murine model8
Structures, biomimetic synthesis, and anti-SARS-CoV-2 activity of two pairs of enantiomeric phenylpropanoid-conjugated protoberberine alkaloids from the rhizomes of Corydalis decumbens8
Apocynin abrogates methotrexate-induced nephrotoxicity: role of TLR4/NF-κB-p65/p38-MAPK, IL-6/STAT-3, PPAR-γ, and SIRT1/FOXO3 signaling pathways8
Regulation of NOX/p38 MAPK/PPARα pathways and miR-155 expression by boswellic acids reduces hepatic injury in experimentally-induced alcoholic liver disease mouse model: novel mechanistic insight8
Phytochemistry and pharmacology of plants in the genus Chaenomeles8
0.030255079269409