Human Immunology

Article	Citations
Next-generation sequencing technologies: An overview	281
The action of TH17 cells on blood brain barrier in multiple sclerosis and experimental autoimmune encephalomyelitis	57
Humoral immune mechanisms involved in protective and pathological immunity during COVID-19	45
Dynamic changes in monocytes subsets in COVID-19 patients	44
The immunogenetic diversity of the HLA system in Mexico correlates with underlying population genetic structure	38
Utilizing nanopore sequencing technology for the rapid and comprehensive characterization of eleven HLA loci; addressing the need for deceased donor expedited HLA typing	37
pHLA3D: Updating the database of predicted three-dimensional structures of HLA with HLA-DR, HLA-DQ and HLA-DP molecules	34
Exhausted NK cells and cytokine storms in COVID-19: Whether NK cell therapy could be a therapeutic choice	33
Pharmacological approach for the reduction of inflammatory and prothrombotic hyperactive state in COVID-19 positive patients by acting on complement cascade	31
Targeting adenosine and regulatory T cells in cancer immunotherapy	30
High-resolution HLA typing by long reads from the R10.3 Oxford nanopore flow cells	28
Review of the immune mechanisms of preeclampsia and the potential of immune modulating therapy	27
Characteristics of immune cells and cytokines in patients with coronavirus disease 2019 in Guangzhou, China	26
A practical guide to chimerism analysis: Review of the literature and testing practices worldwide	25
A role for both HLA-F and HLA-G in reproduction and during pregnancy?	25
A long road/read to rapid high-resolution HLA typing: The nanopore perspective	24
PD-1 silencing improves anti-tumor activities of human mesothelin-targeted CAR T cells	24
Naming HLA diversity: A review of HLA nomenclature	23
Antigen presentation in SARS-CoV-2 infection: the role of class I HLA and ERAP polymorphisms	23
The pro-Inflammatory cytokines effects on mobilization, self-renewal and differentiation of hematopoietic stem cells	23
New challenges, new opportunities: Next generation sequencing and its place in the advancement of HLA typing	22
HLA-DQ mismatches stimulate de novo donor specific antibodies in heart transplant recipients	20
Predictive immunogenetic markers in COVID-19	20
Soluble HLA-G is upregulated in serum of patients with severe COVID-19	19
New genetic predictors for abacavir tolerance in HLA-B*57:01 positive individuals	19

Chemotherapy vs. Immunotherapy in combating nCOVID19: An update	19
A new set of reagents and related software used for NGS based classical and non-classical HLA typing showing evidence for a greater HLA haplotype diversity	18
Contribution of macrophages to fetomaternal immunological tolerance	18
Computational design of a novel multi-epitope vaccine against Coxiella burnetii	18
Puzzling out the COVID-19: Therapy targeting HLA-G and HLA-E	18
High-resolution HLA allele and haplotype frequencies in several unrelated populations determined by next generation sequencing: 17th International HLA and Immunogenetics Workshop joint report	17
The role of immune-mediated alterations and disorders in ALS disease	17
Eplet mismatch scores and de novo donor-specific antibody development in simultaneous pancreas-kidney transplantation	17
Challenges in the application of NGS in the clinical laboratory	16
HLA-E typing of more than 2.5 million potential hematopoietic stem cell donors: Methods and population-specific allele frequencies	15
Role of the HLA-G immune checkpoint molecule in pregnancy	15
Landscapes and dynamic diversifications of B-cell receptor repertoires in COVID-19 patients	15
Distribution of CD36 deficiency in different Chinese ethnic groups	14
The acidic tumour microenvironment: Manipulating the immune response to elicit escape	14
The role of decidual regulatory T cells in the induction and maintenance of fetal antigen-specific tolerance: Imbalance between regulatory and cytotoxic T cells in pregnancy complications	14
Pregnancy induced TMA in severe preeclampsia results from complement-mediated thromboinflammation	14
The B7-H4 gene induces immune escape partly via upregulating the PD-1/Stat3 pathway in non-small cell lung cancer	14
Expression of membrane-bound human leucocyte antigen-G in systemic sclerosis and systemic lupus erythematosus	14
Anti-AT1R autoantibodies and prediction of the severity of Covid-19	14
NGS and HLA: The long road ahead	13
Implementation of molecular matching in transplantation requires further characterization of both immunogenicity and antigenicity of individual HLA epitopes	13
A snapshot of human leukocyte antigen (HLA) diversity using data from the Allele Frequency Net Database	13
COVID-19 does not impact HLA antibody profile in a series of waitlisted renal transplant candidates	13
Genome Canada precision medicine strategy for structured national implementation of epitope matching in renal transplantation	13
Roles and Regulation of Growth differentiation factor-15 in the Immune and tumor microenvironment	13
Clinical utility of next generation sequencing based HLA typing for disease association and pharmacogenetic testing	13
Circulating IFN-γ producing CD4+ T cells and IL-17A producing CD4+ T cells, HLA-shared epitope and ACPA may characterize the clinical response to therapy in rheumatoid arthritis patients	13
HLA-DRB1*04 may predict the severity of disease in a group of Iranian COVID-19 patients	13
Expression analysis of immune-regulatory molecules HLA-G, HLA-E and IDO in endometrial cancer	13
Improving the function of neutrophils from chronic granulomatous disease patients using mesenchymal stem cells’ exosomes	12
Molecular and immunological developments in placentas	12
High fructose diet: A risk factor for immune system dysregulation	12
The respective relevance of sensitization to alloantigens and xenoantigens in pig organ xenotransplantation	12
Lactic acid in alternative polarization and function of macrophages in tumor microenvironment	12
Cytometry-based analysis of HLA-G functions according to ILT2 expression	12
Human leukocyte antigen class-I variation is associated with atopic dermatitis: A case-control study	12
Genetic polymorphisms and expression of NLRP3 inflammasome-related genes are associated with Philadelphia chromosome-negative myeloproliferative neoplasms	12
Incidence and impact of allele-specific anti-HLA antibodies and high-resolution HLA genotyping on assessing immunologic compatibility	11
Current donor selection strategies for allogeneic hematopoietic cell transplantation	11
Development of de novo HLA donor specific antibodies (HLA-DSA), HLA antibodies (HLA-Ab) and allograft rejection post blood transfusion in kidney transplant recipients	11
Increased Indoleamine 2, 3-Dioxygenase expression modulates Th1/Th17/Th22 and Treg pathway in humans with Helicobacter Pylori-Infected gastric mucosa	11
Next-generation sequencing for inborn errors of immunity	11
Immunogenicity, effectiveness, safety and psychological impact of COVID-19 mRNA vaccines	10
Genetic polymorphisms of proteasome subunit genes of the MHC-I antigen-presenting system are associated with cervical cancer in a Chinese Han population	10
Association of vimentin antibody and other non-HLA antibodies with treated antibody mediated rejection in heart transplant recipients	10
The utility of second single antigen bead assay: Clearing the water or stirring up mud?	10
HLA haplotype frequency estimation for heterogeneous populations using a graph-based imputation algorithm	10
Peripheral cells from patients with systemic sclerosis disease co-expressing M1 and M2 monocyte/macrophage surface markers: Relation to the degree of skin involvement	10
ARHGDIB and AT1R autoantibodies are differentially related to the development and presence of chronic antibody-mediated rejection and fibrosis in kidney allografts	10
Vitamin D and risk of ankylosing spondylitis: A two-sample mendelian randomization study	10

HLA-G 3′ untranslated region gene variants are promising prognostic factors for BK polyomavirus replication and acute rejection after living-donor kidney transplant	10
Cytokine IP-10 and GM-CSF are prognostic biomarkers for severity in secondary dengue infection	10
Diagnosing coeliac disease: A literature review	10
The immune potential of decidua-resident CD16+CD56+ NK cells in human pregnancy	9
A clinician’s guide to HLA matching in allogeneic hematopoietic stem cell transplant	9
How natural selection shapes genetic differentiation in the MHC region: A case study with Native Americans	9
Cell-free DNA diagnostics in transplantation utilizing next generation sequencing	9
In utero immune programming of autism spectrum disorder (ASD)	9
Oncolytic virotherapy in hematopoietic stem cell transplantation	9
High-resolution HLA allele and haplotype frequencies of the Saudi Arabian population based on 45,457 individuals and corresponding stem cell donor matching probabilities	9
Current HLA testing recommendations to support HCT	9
HLA-B*15 predicts survival in Egyptian patients with COVID-19	9
Changes in T helper cell-related factors in patients with type 2 diabetes mellitus after empagliflozin therapy	9
High resolution allele genotyping and haplotype frequencies for NGS based HLA 11 loci of 5266 Hong Kong Chinese bone marrow donors	9
HLA repertoire of 115 UAE nationals infected with SARS-CoV-2	8
Genetic variants in the NF-κB signaling pathway (NFKB1, NFKBIA, NFKBIZ) and risk of critical outcome among COVID-19 patients	8
Antinuclear antibodies in patients with endometriosis: A cross-sectional study in 94 patients	8
The utility of imputation for molecular mismatch analysis in solid organ transplantation	8
Applications of next-generation sequencing in hematologic malignancies	8
Evolution of HLA testing for hematopoietic stem cell transplantation: Importance of the candidate’s antibody profile for donor selection	8
Myeloid-derived suppressor cells and regulatory T cells share common immunoregulatory pathways-related microRNAs that are dysregulated by acute lymphoblastic leukemia and chemotherapy	8
Implication of IL-17 producing ɑβT and γδT cells in patients with ovarian cancer	8
HLA-G and humanized mouse models as a novel therapeutic approach in transplantation	8
Not all eplet mismatches are created equal – A cohort study illustrating implications to long-term graft outcomes	7
Soluble HLA-G pre-transplant levels to identify the risk for development of infection in heart transplant recipients	7
Microbiome analysis, the immune response and transplantation in the era of next generation sequencing	7
LINC00323 mediates the role of M1 macrophage polarization in diabetic nephropathy through PI3K/AKT signaling pathway	7
Hyperglycemia and dyslipidemia: Reduced HLA-DR expression in monocyte subpopulations from diabetes patients	7
IL32: The multifaceted and unconventional cytokine	7
T follicular helper cell-mediated IL-21 production suppresses FOXP3 expression of T follicular regulatory-like cells in diffuse large B cell lymphoma patients	7
Frequencies and haplotype associations of non-expressed HLA alleles in ethnically diverse populations on the National Marrow Donor Program’s Be The Match Registry	7
Tri-SNP polymorphism in the intron of HLA-DRA1 affects type 1 diabetes susceptibility in the Finnish population	7
The role of immune cells in pulmonary hypertension: Focusing on macrophages	7
Human CD3+CD56+NKT-like cells express a range of complement receptors and C3 activation has negative effects on these cell activity and effector function	7
Designing of a bispecific antibody against SARS-CoV-2 spike glycoprotein targeting human entry receptors DPP4 and ACE2	7
T cell subpopulations and cytokine levels in hemodialysis patients	7
T cell senescence and impaired CMV-specific response are associated with infection risk in kidney transplant recipients	7
Association of VEGF-A and KDR polymorphisms with the development of schizophrenia	6
Role of BTLA/HVEM network in development of gastric cancer	6
Detection of serum soluble HLA-G levels in patients with acute ischemic stroke: A pilot study	6
Critical amino acid variants in HLA-DRB1 allotypes in the development of Graves’ disease and Hashimoto’s thyroiditis in the Japanese population	6
Vitamin D decreases expression of NLRP1 and NLRP3 inflammasomes in placental explants from women with preeclampsia cultured with hydrogen peroxide	6
MiR-155 regulates Th9 differentiation in children with methicillin-resistant Staphylococcus aureus pneumonia by targeting SIRT1	6
Impact of donor KIRs and recipient KIR/HLA class I combinations on GVHD in patients with acute leukemia after HLA-matched sibling HSCT	6
Association of HLA class II (-DRB1,-DQB1,-DPB1) alleles and haplotypes on susceptibility to aplastic anemia in northern Chinese Han	6
Conserved HLA binding peptides from five non-structural proteins of SARS-CoV-2—An in silico glance	6
Next-generation sequencing and clinical histocompatibility testing	6
Genetic diversity of HLA system in two populations from Yucatán, Mexico: Mérida and rural Yucatán	6
Regulatory noncoding RNAs and the major histocompatibility complex	6
Reducing number of laboratories performing complement dependent cytotoxicity crossmatching: Reasons and conclusions	6
Molecular histocompatibility beyond Tears: The next generation version	6
Physical Crossmatching vs Virtual Crossmatching: The end of an era? or Why give up a good thing?	6
Reduced PCR-generated errors from a hybrid capture-based NGS assay for HLA typing	5
Predicting HLA-DPB1 permissive probabilities through a DPB1 prediction service towards the optimization of HCT donor selection	5
Interaction between functional polymorphisms in FCER1A and TLR2 and the severity of atopic dermatitis	5
The impact of microRNAs on myeloid-derived suppressor cells in cancer	5
HLA B53 is associated with a poor outcome in black COVID-19 patients	5
HLA-disease association and pleiotropy landscape in over 235,000 Finns	5
“Transplantomics” for predicting allograft rejection: real-life applications and new strategies from Network Medicine	5
Ionizing radiation and toll like receptors: A systematic review article	5
Administration of high titer convalescent anti-SARS-CoV-2 plasma: From donor selection to monitoring recipient outcomes	5
Review: HLA loss and detection in the setting of relapse from HLA-mismatched hematopoietic cell transplant	5
HLA-DPB1 and HLA-C alleles are associated with leprosy in a Brazilian population	5
hlaR: A rapid and reproducible tool to identify eplet mismatches between transplant donors and recipients	5
Concurrent typing of over 4000 samples by long-range PCR amplicon-based NGS and rSSO revealed the need to verify NGS typing for HLA allelic dropouts	5
From antigens to eplets: The evolution of HLA	5
Circulating long noncoding RNAs as novel bio-tools: Focus on autoimmune diseases	5
Donor selection based on NK alloreactivity for patients with hematological malignancies	5
Dopamine promotes the progression of AML via activating NLRP3 inflammasome and IL-1β	5
Detection and characterization of the novel HLA-DPA1*02:66:02N allele, with a premature stop codon in exon 2	5
Gene expression patterns associated with tumor-infiltrating CD4+ and CD8+ T cells in invasive breast carcinomas	5
Polymorphisms in CTLA-4 predict de novo donor specific antibody formation after kidney transplantation	4
Identification of novel HLA alleles discovered in 2019–2021	4
Nigella sativa oil inhibits proliferation and stimulates apoptosis of human lymphocytes in vitro	4
HLA-G 14-bp insertion/deletion polymorphism and risk of coronavirus disease 2019 (COVID-19) among Iraqi patients	4
Genetic diversity of HLA system in six populations from Mexico City Metropolitan Area, Mexico: Mexico City North, Mexico City South, Mexico City East, Mexico City West, Mexico City Center and rural Me	4
Allelic and haplotypic HLA diversity in indigenous Malaysian populations explored using Next Generation Sequencing	4
Contribution of survivin to the immune system, allergies and autoimmune diseases	4
Concordance between predicted HLA type using next generation sequencing data generated for non-HLA purposes and clinical HLA type	4
Challenges for the standardized reporting of NGS HLA genotyping: Surveying gaps between clinical and research laboratories	4

Preclinical rationale and current pathways to support the first human clinical trials in cardiac xenotransplantation	4
Genetic diversity of HLA system in two populations from Oaxaca, Mexico: Oaxaca city and rural Oaxaca	4
Performance characteristics of chimerism testing by next generation sequencing	4
HLA antibodies are associated with deterioration of kidney allograft function irrespective of donor specificity	4
The changing landscape of HLA typing: Understanding how and when HLA typing data can be used with confidence from bench to bedside	4
Therapeutic effects of soluble human leukocyte antigen G2 isoform in lupus-prone MRL/lpr mice	4
Association of HLA-G 3′UTR polymorphisms and haplotypes with colorectal cancer susceptibility and prognosis	4
Distribution of HLA-A, -B, -C, -DRB1, -DQB1, -DPB1 allele frequencies in patients with COVID-19 bilateral pneumonia in Russians, living in the Chelyabinsk region (Russia)	4
Immune and gene expression profiling during tacrolimus to everolimus conversion early after liver transplantation	4
Expression level of immune checkpoint inhibitory factors in preeclampsia	4
TRBV and TRBJ usage, when paired with specific HLA alleles, associates with distinct head and neck cancer survival rates	4
False-positive reactivity of anti-human leukocyte antigen antibodies detected using the single-antigen bead assay	4
Increase of autophagy marker p62 in the placenta from pregnant women with preeclampsia	4
Accommodation in allogeneic and xenogeneic organ transplantation: Prevalence, impact, and implications for monitoring and for therapeutics	4
Childhood allergy susceptibility: The role of the immune system development in the in-utero period	4
A high concentration of TGF-β correlates with opportunistic infection in liver and kidney transplantation	4
Genetic diversity of HLA system in two populations from Chiapas, Mexico: Tuxtla Gutiérrez and rural Chiapas	4
Is the level of HLA eplet mismatch a risk factor for graft loss among kidney transplant recipients who have already formed de novo donor specific antibody?	4