Human Immunology

Article	Citations
Next-generation sequencing technologies: An overview	393
Dynamic changes in monocytes subsets in COVID-19 patients	48
Humoral immune mechanisms involved in protective and pathological immunity during COVID-19	45
pHLA3D: Updating the database of predicted three-dimensional structures of HLA with HLA-DR, HLA-DQ and HLA-DP molecules	40
Exhausted NK cells and cytokine storms in COVID-19: Whether NK cell therapy could be a therapeutic choice	37
Review of the immune mechanisms of preeclampsia and the potential of immune modulating therapy	36
Targeting adenosine and regulatory T cells in cancer immunotherapy	33
Naming HLA diversity: A review of HLA nomenclature	32
Pharmacological approach for the reduction of inflammatory and prothrombotic hyperactive state in COVID-19 positive patients by acting on complement cascade	32
High-resolution HLA typing by long reads from the R10.3 Oxford nanopore flow cells	32
A practical guide to chimerism analysis: Review of the literature and testing practices worldwide	30
PD-1 silencing improves anti-tumor activities of human mesothelin-targeted CAR T cells	29
New challenges, new opportunities: Next generation sequencing and its place in the advancement of HLA typing	28
Characteristics of immune cells and cytokines in patients with coronavirus disease 2019 in Guangzhou, China	28
A long road/read to rapid high-resolution HLA typing: The nanopore perspective	27
Antigen presentation in SARS-CoV-2 infection: the role of class I HLA and ERAP polymorphisms	25
Predictive immunogenetic markers in COVID-19	25
Contribution of macrophages to fetomaternal immunological tolerance	23
High-resolution HLA allele and haplotype frequencies in several unrelated populations determined by next generation sequencing: 17th International HLA and Immunogenetics Workshop joint report	22
Chemotherapy vs. Immunotherapy in combating nCOVID19: An update	22
Soluble HLA-G is upregulated in serum of patients with severe COVID-19	21
Challenges in the application of NGS in the clinical laboratory	20
Role of the HLA-G immune checkpoint molecule in pregnancy	20
Eplet mismatch scores and de novo donor-specific antibody development in simultaneous pancreas-kidney transplantation	20
Puzzling out the COVID-19: Therapy targeting HLA-G and HLA-E	19

HLA-E typing of more than 2.5 million potential hematopoietic stem cell donors: Methods and population-specific allele frequencies	18
High fructose diet: A risk factor for immune system dysregulation	18
Landscapes and dynamic diversifications of B-cell receptor repertoires in COVID-19 patients	18
Implementation of molecular matching in transplantation requires further characterization of both immunogenicity and antigenicity of individual HLA epitopes	18
The acidic tumour microenvironment: Manipulating the immune response to elicit escape	18
A snapshot of human leukocyte antigen (HLA) diversity using data from the Allele Frequency Net Database	18
The role of immune-mediated alterations and disorders in ALS disease	17
Anti-AT1R autoantibodies and prediction of the severity of Covid-19	16
HLA-DRB1*04 may predict the severity of disease in a group of Iranian COVID-19 patients	16
Roles and Regulation of Growth differentiation factor-15 in the Immune and tumor microenvironment	16
The role of decidual regulatory T cells in the induction and maintenance of fetal antigen-specific tolerance: Imbalance between regulatory and cytotoxic T cells in pregnancy complications	15
Pregnancy induced TMA in severe preeclampsia results from complement-mediated thromboinflammation	15
Lactic acid in alternative polarization and function of macrophages in tumor microenvironment	14
Diagnosing coeliac disease: A literature review	14
Genome Canada precision medicine strategy for structured national implementation of epitope matching in renal transplantation	14
Human leukocyte antigen class-I variation is associated with atopic dermatitis: A case-control study	13
Incidence and impact of allele-specific anti-HLA antibodies and high-resolution HLA genotyping on assessing immunologic compatibility	13
Peripheral cells from patients with systemic sclerosis disease co-expressing M1 and M2 monocyte/macrophage surface markers: Relation to the degree of skin involvement	13
Molecular and immunological developments in placentas	13
Current donor selection strategies for allogeneic hematopoietic cell transplantation	13
COVID-19 does not impact HLA antibody profile in a series of waitlisted renal transplant candidates	13
Next-generation sequencing for inborn errors of immunity	12
Vitamin D and risk of ankylosing spondylitis: A two-sample mendelian randomization study	12
Antinuclear antibodies in patients with endometriosis: A cross-sectional study in 94 patients	12
Cytokine IP-10 and GM-CSF are prognostic biomarkers for severity in secondary dengue infection	12
Increased Indoleamine 2, 3-Dioxygenase expression modulates Th1/Th17/Th22 and Treg pathway in humans with Helicobacter Pylori-Infected gastric mucosa	12
Hyperglycemia and dyslipidemia: Reduced HLA-DR expression in monocyte subpopulations from diabetes patients	12
The respective relevance of sensitization to alloantigens and xenoantigens in pig organ xenotransplantation	12
HLA haplotype frequency estimation for heterogeneous populations using a graph-based imputation algorithm	12
The role of immune cells in pulmonary hypertension: Focusing on macrophages	11
ARHGDIB and AT1R autoantibodies are differentially related to the development and presence of chronic antibody-mediated rejection and fibrosis in kidney allografts	11
HLA-disease association and pleiotropy landscape in over 235,000 Finns	11
Cell-free DNA diagnostics in transplantation utilizing next generation sequencing	11
Tri-SNP polymorphism in the intron of HLA-DRA1 affects type 1 diabetes susceptibility in the Finnish population	11
Current HLA testing recommendations to support HCT	11
Immunogenicity, effectiveness, safety and psychological impact of COVID-19 mRNA vaccines	11
Applications of next-generation sequencing in hematologic malignancies	11
How natural selection shapes genetic differentiation in the MHC region: A case study with Native Americans	11
Association of vimentin antibody and other non-HLA antibodies with treated antibody mediated rejection in heart transplant recipients	11
HLA-B*15 predicts survival in Egyptian patients with COVID-19	11
A clinician’s guide to HLA matching in allogeneic hematopoietic stem cell transplant	11
Changes in T helper cell-related factors in patients with type 2 diabetes mellitus after empagliflozin therapy	11
IL32: The multifaceted and unconventional cytokine	10
Molecular histocompatibility beyond Tears: The next generation version	10
Myeloid-derived suppressor cells and regulatory T cells share common immunoregulatory pathways-related microRNAs that are dysregulated by acute lymphoblastic leukemia and chemotherapy	10
The utility of second single antigen bead assay: Clearing the water or stirring up mud?	10
Genetic variants in the NF-κB signaling pathway (NFKB1, NFKBIA, NFKBIZ) and risk of critical outcome among COVID-19 patients	10
The immune potential of decidua-resident CD16+CD56+ NK cells in human pregnancy	10
In utero immune programming of autism spectrum disorder (ASD)	10
High-resolution HLA allele and haplotype frequencies of the Saudi Arabian population based on 45,457 individuals and corresponding stem cell donor matching probabilities	10

Association of HLA class II (-DRB1,-DQB1,-DPB1) alleles and haplotypes on susceptibility to aplastic anemia in northern Chinese Han	9
Evolution of HLA testing for hematopoietic stem cell transplantation: Importance of the candidate’s antibody profile for donor selection	9
Role of BTLA/HVEM network in development of gastric cancer	9
Critical amino acid variants in HLA-DRB1 allotypes in the development of Graves’ disease and Hashimoto’s thyroiditis in the Japanese population	9
The utility of imputation for molecular mismatch analysis in solid organ transplantation	9
Oncolytic virotherapy in hematopoietic stem cell transplantation	9
HLA repertoire of 115 UAE nationals infected with SARS-CoV-2	9
MiR-155 regulates Th9 differentiation in children with methicillin-resistant Staphylococcus aureus pneumonia by targeting SIRT1	8
Microbiome analysis, the immune response and transplantation in the era of next generation sequencing	8
Not all eplet mismatches are created equal – A cohort study illustrating implications to long-term graft outcomes	8
hlaR: A rapid and reproducible tool to identify eplet mismatches between transplant donors and recipients	8
Association of VEGF-A and KDR polymorphisms with the development of schizophrenia	8
Reducing number of laboratories performing complement dependent cytotoxicity crossmatching: Reasons and conclusions	8
Review: HLA loss and detection in the setting of relapse from HLA-mismatched hematopoietic cell transplant	7
Dopamine promotes the progression of AML via activating NLRP3 inflammasome and IL-1β	7
Designing of a bispecific antibody against SARS-CoV-2 spike glycoprotein targeting human entry receptors DPP4 and ACE2	7
Next-generation sequencing and clinical histocompatibility testing	7
T cell senescence and impaired CMV-specific response are associated with infection risk in kidney transplant recipients	7
Association of HLA-G 3′UTR polymorphisms and haplotypes with colorectal cancer susceptibility and prognosis	7
Human CD3+CD56+NKT-like cells express a range of complement receptors and C3 activation has negative effects on these cell activity and effector function	7
T cell subpopulations and cytokine levels in hemodialysis patients	7
LINC00323 mediates the role of M1 macrophage polarization in diabetic nephropathy through PI3K/AKT signaling pathway	7
The changing landscape of HLA typing: Understanding how and when HLA typing data can be used with confidence from bench to bedside	7
HLA B53 is associated with a poor outcome in black COVID-19 patients	7
Expression level of immune checkpoint inhibitory factors in preeclampsia	7
“Transplantomics” for predicting allograft rejection: real-life applications and new strategies from Network Medicine	7
Ionizing radiation and toll like receptors: A systematic review article	7
Gene expression patterns associated with tumor-infiltrating CD4+ and CD8+ T cells in invasive breast carcinomas	6
Circulating long noncoding RNAs as novel bio-tools: Focus on autoimmune diseases	6
Donor selection based on NK alloreactivity for patients with hematological malignancies	6
Vitamin D decreases expression of NLRP1 and NLRP3 inflammasomes in placental explants from women with preeclampsia cultured with hydrogen peroxide	6
Reduced PCR-generated errors from a hybrid capture-based NGS assay for HLA typing	6
Predicting HLA-DPB1 permissive probabilities through a DPB1 prediction service towards the optimization of HCT donor selection	6
Contribution of survivin to the immune system, allergies and autoimmune diseases	6
Interaction between functional polymorphisms in FCER1A and TLR2 and the severity of atopic dermatitis	6
Concurrent typing of over 4000 samples by long-range PCR amplicon-based NGS and rSSO revealed the need to verify NGS typing for HLA allelic dropouts	6
HLA-G 14-bp insertion/deletion polymorphism and risk of coronavirus disease 2019 (COVID-19) among Iraqi patients	6
Regulatory noncoding RNAs and the major histocompatibility complex	6
Donor-directed immunologic safety of COVID-19 vaccination in renal transplant recipients	6
Challenges for the standardized reporting of NGS HLA genotyping: Surveying gaps between clinical and research laboratories	6
Childhood allergy susceptibility: The role of the immune system development in the in-utero period	5
HLA-B evolutionary divergence is associated with outcomes after SARS-CoV-2 infection	5
The impact of microRNAs on myeloid-derived suppressor cells in cancer	5
TRBV and TRBJ usage, when paired with specific HLA alleles, associates with distinct head and neck cancer survival rates	5
Role of inflammation and immune response in atherosclerosis: Mechanisms, modulations, and therapeutic targets	5
Neem Leaf Glycoprotein in immunoregulation of cancer	5
CAPG facilitates diffuse large B-cell lymphoma cell progression through PI3K/AKT signaling pathway	5
Allelic and haplotypic HLA diversity in indigenous Malaysian populations explored using Next Generation Sequencing	5
Multi-epitope vaccines, from design to expression; an in silico approach	5
Polymorphisms in CTLA-4 predict de novo donor specific antibody formation after kidney transplantation	5
Detection and characterization of the novel HLA-DPA1*02:66:02N allele, with a premature stop codon in exon 2	5
Performance characteristics of chimerism testing by next generation sequencing	5
Increase of autophagy marker p62 in the placenta from pregnant women with preeclampsia	5
Administration of high titer convalescent anti-SARS-CoV-2 plasma: From donor selection to monitoring recipient outcomes	5
HLA-DPB1 and HLA-C alleles are associated with leprosy in a Brazilian population	5
Distribution of HLA-A, -B, -C, -DRB1, -DQB1, -DPB1 allele frequencies in patients with COVID-19 bilateral pneumonia in Russians, living in the Chelyabinsk region (Russia)	5
HLA-E gene polymorphisms in chronic hepatitis C: Impact on HLA-E liver expression and disease severity	5
From antigens to eplets: The evolution of HLA	5
Accommodation in allogeneic and xenogeneic organ transplantation: Prevalence, impact, and implications for monitoring and for therapeutics	5
Different immunoregulatory components at the decidua basalis of oocyte donation pregnancies	4
Association of HLA-G, HLA-E and HLA-B*27 with susceptibility and clinical phenotype of enthesitis related arthritis (ERA)	4
HLA antigens to epitopes: Meeting the challenge	4
Increased frequency of activated regulatory T cells in patients with lupus nephritis	4
Interplay of immune components and their association with recurrent pregnancy loss	4
Preclinical rationale and current pathways to support the first human clinical trials in cardiac xenotransplantation	4
The role of immune system in atherosclerosis: Molecular mechanisms, controversies, and future possibilities	4
HLA antibodies are associated with deterioration of kidney allograft function irrespective of donor specificity	4
miR-150 promotes progressive T cell differentiation via inhibiting FOXP1 and RC3H1	4
The association of γδ-T cells with bronchopulmonary dysplasia in premature infants	4
A high concentration of TGF-β correlates with opportunistic infection in liver and kidney transplantation	4
Association of the 3′ untranslated region polymorphisms of HLA-G with susceptibility to chronic hepatitis C virus infection in the Chinese population	4
Is the level of HLA eplet mismatch a risk factor for graft loss among kidney transplant recipients who have already formed de novo donor specific antibody?	4
The β2-adrenergic receptor agonist terbutaline upregulates T helper-17 cells in a protein kinase A-dependent manner	4
False-positive reactivity of anti-human leukocyte antigen antibodies detected using the single-antigen bead assay	4
Autobiographical perspectives on HLA epitopes: Past, present and future	4
Graphical user interface for the haplotype frequency estimation software Hapl-o-Mat	4
Associations of human leukocyte antigen with neutralizing antibody titers in a tetravalent dengue vaccine phase 2 efficacy trial in Thailand	4
Altered microRNA expression profile is linked to T-cell exhaustion-related pathways in pediatric patients with acute lymphoblastic leukemia	4
Role of HLA molecular mismatch in clinical practice	4
Immune and gene expression profiling during tacrolimus to everolimus conversion early after liver transplantation	4

Non-classical HLA class I molecules and their potential role in viral infections	4
Identification of novel HLA alleles discovered in 2019–2021	4
Nigella sativa oil inhibits proliferation and stimulates apoptosis of human lymphocytes in vitro	4
Potential and challenges of placenta-derived decidua stromal cell therapy in inflammation-associated disorders	3
CXCL1 promotes immune escape in colorectal cancer by autophagy-mediated MHC-I degradation	3
In-silico study of influence of HLA heterogeneity on CTL responses across ethnicities to SARS-CoV-2	3
Moesin: A novel receptor on NK lymphocytes binds to TOMM40 on K562 leukemia cells initiating cytolysis	3
Determination of unacceptable antigens by summation of anti-HLA eplet antibody strength (MFI) based on single antigen bead assays: Excellent correlation with negative cell based cross matches	3
Pattern recognition receptor expression and maturation profile of dendritic cell subtypes in human tonsils and lymph nodes	3
Endothelial colony forming cells generated from cryopreserved peripheral blood mononuclear cells	3
Availability of HLA-allele-matched unrelated donors and registry size: Estimation from haplotype frequency in the Italian population	3
Concurrent use of two independent methods prevents erroneous HLA typing of deceased organ donors – An important strategy for patient safety and accurate virtual crossmatching for broader sharing	3
HLA-DR, -DP, -DQ expression status of parathyroid tissue as a potential parathyroid donor selection criteria and review of literature	3
Navigating the murky waters of maternal fetal tolerance: Put big data at the helm	3
Synergy of endoplasmic reticulum aminopeptidase 1 and 2 (ERAP1 and ERAP2) polymorphisms in atopic dermatitis: Effects on disease prevalence	3
Downregulation of CD73 on CD4+ T cells from patients with chronic Chikungunya infection	3
Expression of cathelicidin, ERK, MyD88, and TLR-9 in the blood of women in the pre-pregnancy, pregnancy, and their infant cord blood	3
HLA allele and haplotype frequencies in the Panamanian population	3
Association between SARS-CoV-2 infection and de novo HLA donor specific antibody production in lung transplant recipients: Single-center study	3
HLA epitopes – Empirically defined as conformational amino acids sequences of the HLA antigen and are likely to be part of the binding sites of anti-HLA antibodies	3
Assessment of Rapid Optimized 96-well Tray Flow Cytometric Crossmatch (Halifax-FCXM) with Luminex Single Antigen Test	3
HLA-E*01:01 allele is associated with better response to anti-HCV therapy while homozygous status for HLA-E*01:03 allele increases the resistance to anti-HCV treatments in frequently transfused thalas	3
T helper-9 cells and Interleukin-9 in transplantation: The open question	3
Impact of HLA polymorphisms on the susceptibility to SARS-CoV-2 infection and related mortality in patients with renal replacement therapy	3
Diminished Interleukin-7 receptor expression on T-cell subsets in tuberculosis patients	3
Sex-dependent regulation of interferon-γ receptor expression in pulmonary tuberculosis	3
Combined imputation of HLA genotype and self-identified race leads to better donor-recipient matching	3
Association of polymorphisms of innate immunity-related genes and tuberculosis susceptibility in Mongolian population	3
Subclinical inflammation in the preclinical phase of rheumatoid arthritis might contribute to articular joint damage	3
Abrogating biologics interference in flow cytometric crossmatching	3
HLA homozygosity is associated with Non-Hodgkin lymphoma	3
Virtual crossmatch for deceased donor kidney transplantation in the United States: A survey of histocompatibility lab directors and transplant surgeons	3
Astragalus-mediated stimulation on antigen-presenting cells could result in higher IL-21 production from CXCR5+ Tfh-like cells and better IL-21-mediated effector functions	3
Self-reactive antibodies associated with bronchiolitis obliterans syndrome subtype of chronic lung allograft dysfunction	3
Myeloid-derived suppressor cells: Important communicators in systemic lupus erythematosus pathogenesis and its potential therapeutic significance	3
Association study between HLA-A, -B, -C, -DRB1 alleles and Psoriatic arthritis in southern France	3
Coexistence of sickle cell disease and systemic lupus erythematosus is associated with quantitative and qualitative impairments in circulating regulatory B cells	3
Aberrant expression of inhibitory receptors on B cells in patients with Graves’ disease	3
KIR genotype and haplotype frequencies in the multi-ethnic population of Malaysia	2
Value of diagnostic vaccination in diagnosis of humoral inborn errors of immunity	2
Tools for optimizing risk assessment in hematopoietic cell transplant – What can we get away with?	2
A comparative study on regulation of HLA-G expression in bad obstetric history and in head and neck squamous cell carcinoma from Northeast India	2
Risk HLA alleles in South America and potential new epitopes for SARS-CoV2	2
Complement-dependent cytotoxicity crossmatch in solid organ transplantation: The gold standard or golden history?	2
COVID-19 infection and vaccination rarely impact HLA antibody profile in waitlisted renal transplant candidates- a multicenter cohort	2
A comprehensive review on the role of T cell subsets and CAR-T cell therapy in Aspergillus fumigatus infection	2
Predicting the functional consequences of genetic variants in co-stimulatory ligand B7-1 using in-silico approaches	2
FOXP3+/CD68+ ratio within the tumor microenvironment may serve as a potential prognostic factor in classical Hodgkin lymphoma	2
Nomenclature for factors of the HLA system, update January, February and March 2021	2
Th1 or Th2 cytokines are correlated with Tregs and T cell subsets and pregnancy outcomes in patients with autoimmune thyroid disease during early, middle, late pregnancy, and postpartum period	2
Sex-dependent effect of aging on calcium signaling and expression of TRPM2 and CRAC channels in human neutrophils	2
Differences in T cell immune-related lncRNA and mRNA expression patterns between right- and left-sided colorectal cancers	2
Contribution of HLA-G and FOXP3 genes and proteins in the severity of cervical intraepithelial neoplasia during HPV infection	2
The role of the HLA allelic repertoire on the clinical severity of COVID-19 in Canadians, living in the Saskatchewan province	2
The function of IL-33/ST2 signaling axis in treg cells activating fibrosis in IgG4-related disease	2
Combining nano-curcumin with catechin improves COVID-19-infected patient's inflammatory conditions	2
Identification of a CD4+ T cell line with Treg-like activity	2
Allelic Polymorphisms of Killer Immunoglobulin-Like Receptor Genes in Malay and Orang Asli Populations of Peninsular Malaysia	2
Microarray analysis of autoantibodies can identify future Systemic Lupus Erythematosus patients	2
HLA-G susceptibility to hepatitis B infection and related hepatocellular carcinoma in the Japanese population	2
KIR copy number variations in dengue-infected patients from northeastern Thailand	2
IL-10-producing memory B regulatory cells as a novel target for HLA-G to prolong human kidney allograft survival	2
The association of TAP polymorphisms with non-small-cell lung cancer in the Han Chinese population	2
The relevance of HLA class II genes in JAK2 V617F-positive myeloproliferative neoplasms	2
Human leukocyte antigen association with azathioprine-induced drug hypersensitivity reactions in patients with anti-neutrophil cytoplasmic antibody associated vasculitis	2
Lower PTEN may be associated with CD8+ T cell exhaustion in diffuse large B-cell lymphoma	2
Is peripheral blood immunophenotyping useful to understand the etiology of Idiopathic Granulomatous?	2
Altered regulatory T cell-mediated Natural Killer cells suppression may lead to generalized vitiligo	2
DNA methylation and expression of LGR6 gene in ankylosing spondylitis: A case-control study	2
MBL2 gene polymorphisms related to HIV-1 infection susceptibility and treatment response	2
An inclusive study on cytokine gene expression in Parkinson's disease: Advanced analysis using Bayesian regression model	2
Impact of T helper cells on bone metabolism in systemic lupus erythematosus	2
Prevalence of AT1R antibody (AT1R-Ab) among Malaysian multi-ethnic population	2
Investigating viral and autoimmune T cell responses associated with post-acute sequelae of COVID-19	2
Loss of immune regulation in aged T-cells: A metabolic review to show lack of ability to control responses within the self	2
The expression and function of immunoglobulin-like transcript 4 in dendritic cells from patients with hepatocellular carcinoma	2