OOIR: Observatory of International Research

Papers

(The H4-Index of Medicinal Research Reviews is 40. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications	320
Molecular targeting therapies for neuroblastoma: Progress and challenges	177
The role of hypoxia‐inducible factor 1 in tumor immune evasion	173
Understanding the tumor microenvironment for effective immunotherapy	164
Artificial intelligence and machine learning‐aided drug discovery in central nervous system diseases: State‐of‐the‐arts and future directions	164
Mechanisms of melanocyte death in vitiligo	136
A review in radiomics: Making personalized medicine a reality via routine imaging	128
Tripterygium wilfordii: An inspiring resource for rheumatoid arthritis treatment	120
Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections	105
Phytochemistry and cardiovascular protective effects of Huang‐Qi (Astragali Radix)	98
The immunosuppressive activity of artemisinin‐type drugs towards inflammatory and autoimmune diseases	94
Metabolites of microbiota response to tryptophan and intestinal mucosal immunity: A therapeutic target to control intestinal inflammation	88
Emerging roles of SIRT6 in human diseases and its modulators	86
What coronavirus 3C‐like protease tells us: From structure, substrate selectivity, to inhibitor design	85
Glycogen synthesis and beyond, a comprehensive review of GSK3 as a key regulator of metabolic pathways and a therapeutic target for treating metabolic diseases	75
Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments	75
The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy	71
KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential	70
Direct targeting of β‐catenin in the Wnt signaling pathway: Current progress and perspectives	68
Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review	66
Extracellular vesicles: Emerging frontiers in wound healing	63
Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds	63
Strategies for designing proteolysis targeting chimaeras (PROTACs)	59
Expedition of sulfur‐containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update	53
(Nano)platforms in breast cancer therapy: Drug/gene delivery, advanced nanocarriers and immunotherapy	52

Metabolomics as a tool for the early diagnosis and prognosis of diabetic kidney disease	52
Haste makes waste: A critical review of docking‐based virtual screening in drug repurposing for SARS‐CoV‐2 main protease (M‐pro) inhibition	51
Cardiac efficacy and toxicity of aconitine: A new frontier for the ancient poison	50
Immunomodulatory potential of natural products from herbal medicines as immune checkpoints inhibitors: Helping to fight against cancer via multiple targets	50
Cistanches Herba, from an endangered species to a big brand of Chinese medicine	48
Trends in targeted delivery of nanomaterials in colon cancer diagnosis and treatment	48
Biosynthesis, total synthesis, structural modifications, bioactivity, and mechanism of action of the quinone‐methide triterpenoid celastrol	46
Upgrade of an old drug: Auranofin in innovative cancer therapies to overcome drug resistance and to increase drug effectiveness	46
Inflammatory bowel disease biomarkers	45
The Yin and Yang of traditional Chinese and Western medicine	44
Association predictions of genomics, proteinomics, transcriptomics, microbiome, metabolomics, pathomics, radiomics, drug, symptoms, environment factor, and disease networks: A comprehensive approach	44
Progress and perspective on hydrogen sulfide donors and their biomedical applications	42
Protein corona formed in the gastrointestinal tract and its impacts on oral delivery of nanoparticles	42
Recent progress and new perspectives for diterpenoid biosynthesis in medicinal plants	41
Salinomycin as a potent anticancer stem cell agent: State of the art and future directions	40