Neurobiology of Aging

Article	Citations
The genetic overlap between Alzheimer’s disease, amyotrophic lateral sclerosis, Lewy body dementia, and Parkinson’s disease	436
Paradoxical cognitive trajectories in men from earlier to later adulthood	164
Machine learning approaches based on fibroblast morphometry do not predict ALS	91
Association of rare heterozygous PLA2G6 variants with the risk of Parkinson's disease	91
Protein retention in the endoplasmic reticulum rescues Aβ toxicity in Drosophila	73
Amyloid-β positive individuals with subjective cognitive decline present increased CSF neurofilament light levels that relate to lower hippocampal volume	51
Chronic BMAA exposure combined with TDP-43 mutation elicits motor neuron dysfunction phenotypes in mice	49
Reactivity of posterior cortical electroencephalographic alpha rhythms during eyes opening in cognitively intact older adults and patients with dementia due to Alzheimer's and Lewy body diseases	49
Age-related synaptic signatures of brain and cognitive reserve in the rat hippocampus and parahippocampal regions	47
Topological changes of fast large-scale brain dynamics in mild cognitive impairment predict early memory impairment: a resting-state, source reconstructed, magnetoencephalography study	46
The association between hippocampal volume and memory in pathological aging is mediated by functional redundancy	45
Blood pressure changes impact corticospinal integrity and downstream gait and balance control	45
Editorial Advisory Board	44
Altered network stability in progressive supranuclear palsy	43
Mitochondrial pathway polygenic risk scores are associated with Alzheimer's Disease	39
Unlocking the causal link of metabolically different adiposity subtypes with brain volumes and the risks of dementia and stroke: A Mendelian randomization study	38
Age-dependent relationship of cardiorespiratory fitness and white matter integrity	37
Genotype-phenotype correlation of Parkinson's disease with PRKN variants	36
Isoform-specific effects of neuronal inhibition of AMPK catalytic subunit on LTD impairments in a mouse model of Alzheimer’s disease	35
CRYAB plays a role in terminating the presence of pro-inflammatory macrophages in the older, injured mouse peripheral nervous system	34
Trajectories of amyloid beta accumulation – Unveiling the relationship with APOE genotype and cognitive decline	33
Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is associated with abnormalities in white matter structural integrity and connectivity: An ex-vivo diffusion MRI	33
Associations of cerebrovascular disease and Alzheimer’s disease pathology with cognitive decline: Analysis of the National Alzheimer’s Coordinating Center Uniform Data Set	31
Predicting brain atrophy and cognitive aging trajectories with baseline subjective cognitive concerns in cognitively normal older adults	30
Spontaneous prion disease in homozygous and heterozygous transgenic mouse models of T188K genetic Creutzfeldt-Jakob disease	29

Low-moderate dose whole-brain γ-ray irradiation modulates the expressions of glial fibrillary acidic protein and intercellular adhesion molecule-1 in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine–i	29
Association between metabolic syndrome and resting-state functional brain connectivity	28
Age-related differences in ERP correlates of value-based decision making	28
Association of the CD2AP locus with cognitive functioning among middle-aged individuals with a family history of Alzheimer's disease	28
Comparison of age-related declines in behavioral auditory responses versus electrophysiological measures of amplitude modulation	28
Divergent magnetic resonance imaging atrophy patterns in Alzheimer's disease and primary age-related tauopathy	27
Dynactin 6 deficiency enhances aging-associated dystrophic neurite formation in mouse brains	27
Relationship between regional white matter hyperintensities and alpha oscillations in older adults	26
Effector-dependent decline in strength and subcortical motor excitability with aging	26
Actigraphy-estimated physical activity is associated with functional and structural brain connectivity among older adults	26
Corrigendum to “Progesterone exerts neuroprotective effects and improves long-term neurologic outcome after intracerebral hemorrhage in middle-aged mice” [Neurobiol. Aging 42 (2016) 13–24]	26
Contents	25
DNA methylation age acceleration is associated with age of onset in Chinese spinocerebellar ataxia type 3 patients	25
Contents	24
Recollection-related fMRI effects in entorhinal cortex predict longitudinal memory change in healthy older adults	24
Longitudinal trajectories of basal forebrain volume in normal aging and Alzheimer’s disease	24
Contents Continued	24
Do age-related differences in aperiodic neural activity explain differences in resting EEG alpha?	24
Medial temporal lobe structure, mnemonic and perceptual discrimination in healthy older adults and those at risk for mild cognitive impairment	24
A cognitive marker for Alzheimer disease pathology in primary progressive aphasia? A validation study in the clinical setting	24
Sleep/wake cycle alterations as a cause of neurodegenerative diseases: A Mendelian randomization study	24
Exploring the links among brain iron accumulation, cognitive performance, and dietary intake in older adults: A longitudinal MRI study	24
Inosine monophosphate dehydrogenase intranuclear inclusions are markers of aging and neuronal stress in the human substantia nigra	23
More flexible brain activation underlies cognitive reserve in older adults	23
Editorial Advisory Board	23
ApoE4 reduction: An emerging and promising therapeutic strategy for Alzheimer's disease	23
Impact of white matter hyperintensities on structural connectivity and cognition in cognitively intact ADNI participants	23
Voice biomarkers as indicators of cognitive changes in middle and later adulthood	23
TFEB protein expression is reduced in aged brains and its overexpression mitigates senescence-associated biomarkers and memory deficits in mice	23
GABAA receptor agonist muscimol rescues inhibitory microcircuit defects in the olfactory bulb and improves olfactory function in APP/PS1 transgenic mice	22
ANXA1 mutation analysis in Italian patients with early onset PD	22
Zebrafish optomotor response to second-order motion illustrates that age-related changes in motion detection depend on the activated motion system	22
Increased neural differentiation after a single session of aerobic exercise in older adults	22
Editorial: Guide for authors at Neurobiology of Aging	22
Long-term ovarian hormone deprivation alters functional connectivity, brain neurochemical profile and white matter integrity in the Tg2576 amyloid mouse model of Alzheimer's disease	22
Nigrostriatal 6-hydroxydopamine lesions increase alpha-synuclein levels and permeability in rat colon	22
Exploring the domain specificity and the neural correlates of memory unawareness in Alzheimer's disease	22
Examining age-dependent DNA methylation patterns and gene expression in the male and female mouse hippocampus	21
Editorial Advisory Board	21
Resting-state functional connectivity abnormalities in subjective cognitive decline: A 7T MRI study	21
Genetic analysis of GLT8D1 and ARPP21 in Australian familial and sporadic amyotrophic lateral sclerosis	21
Contents	21
Dissociating direct and indirect effects: a theoretical framework of how latent toxoplasmosis affects cognitive profile across the lifespan	21
Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is associated with lower R2 relaxation rate: an ex-vivo MRI and pathology investigation	21
The moderating effect of diet on the relationship between depressive symptoms and Alzheimer’s disease-related blood-based biomarkers	20
Rates of β-amyloid deposition indicate widespread simultaneous accumulation throughout the brain	20
Age-related decline in cochlear ribbon synapses and its relation to different metrics of auditory-nerve activity	20
GLT8D1 may not be significant in Chinese sporadic amyotrophic lateral sclerosis patients	20
High-fat diet and aging-associated memory impairments persist in the absence of microglia in female rats	20
Reduced structural connectivity of the medial temporal lobe including the perforant path is associated with aging and verbal memory impairment	20

Principal components from untargeted cerebrospinal fluid metabolomics associated with Alzheimer's disease biomarkers	20
Shared genetic links between amyotrophic lateral sclerosis and obesity-related traits: a genome-wide association study	20
Hearing loss and its relation to longitudinal changes in white matter microstructure in older adults: The Rotterdam Study	20
Mediterranean diet is associated with lower white matter lesion volume in Mediterranean cities and lower cerebrospinal fluid Aβ42 in non-Mediterranean cities in the EPAD LCS cohort	20
Distinct phosphorylation profiles of tau in brains of patients with different tauopathies	19
EEG measures for clinical research in major vascular cognitive impairment: recommendations by an expert panel	19
Visit-to-visit blood pressure variability and regional cerebral perfusion decline in older adults	19
Neuropsychology of cognitive aging in rhesus monkeys	19
Adult lifespan maturation and degeneration patterns in gray and white matter: A mean apparent propagator (MAP) MRI study	19
Single-neuron whole genome sequencing identifies increased somatic mutation burden in Alzheimer's disease related genes	19
Apolipoprotein E and Alzheimer’s disease pathology in African American older adults	19
Electrophysiological alterations during action semantic processing in Parkinson’s disease	18
Effects of amyloid pathology and the APOE ε4 allele on the association between cerebrospinal fluid Aβ38 and Aβ40 and brain morphology in cognitively normal 70-years-olds	18
Characterising the covariance pattern between lifestyle factors and structural brain measures: a multivariable replication study of two independent ageing cohorts	18
The (hyper)excitable brain: what can a ubiquitous TMS measure reveal about cognitive aging?	18
Modeling functional loss in Alzheimer’s Disease through cognitive reserve and cognitive state: A panel data longitudinal study	18
Contents	18
Patterns of amyloid accumulation in amyloid-negative cases	18
Ensemble-specific deficit in neuronal intrinsic excitability in aged mice	18
Contents	18
Contents	18
Biologic that disrupts PDE11A4 homodimerization in hippocampus CA1 reverses age-related cognitive decline of social memories in mice	17
The association between inadequate sleep and accelerated brain ageing	17
Dopaminergic modulation of working memory and cognitive flexibility in a zebrafish model of aging-related cognitive decline	17
1H MR spectroscopy biomarkers of neuronal and synaptic function are associated with tau deposition in cognitively unimpaired older adults	17
Editorial Advisory Board	17
Biological correlates of elevated soluble TREM2 in cerebrospinal fluid	17
High-resolution mapping identifies HLA class II associations with multifocal motor neuropathy	17
Whole genome sequencing analysis reveals post-zygotic mutation variability in monozygotic twins discordant for amyotrophic lateral sclerosis	17
Age-related differences in how the shape of alpha and beta oscillations change during reaction time tasks	17
Editorial Advisory Board	17
Specific and general relationships between cortical thickness and cognition in older adults: a longitudinal study	17
Mutation analysis of seven SLC family transporters for early-onset Parkinson's disease in Chinese population	17
Genetic overlap between Alzheimer's disease and blood lipid levels	17
Daily biofeedback to modulate heart rate oscillations affects structural volume in hippocampal subregions targeted by the locus coeruleus in older adults but not younger adults	16
Age differences in the neural processing of semantics, within and beyond the core semantic network	16
Editorial Advisory Board	16
Brain oscillatory processes related to sequence memory in healthy older adults	16
Higher motor cortical excitability linked to greater cognitive dysfunction in Alzheimer's disease: results from two independent cohorts	16
Corrigendum to: A clinical, molecular genetics and pathological study of a FTDP-17 family with a heterozygous splicing variant c.823–10 G>T at the intron 9/exon 10 of the MAPT gene	16
Physical activity levels and brain structure in middle-aged and older adults: a bidirectional longitudinal population-based study	16
Previous estradiol treatment during midlife maintains transcriptional regulation of memory-related proteins by ERα in the hippocampus in a rat model of menopause	16
Predicting time-to-conversion for dementia of Alzheimer's type using multi-modal deep survival analysis	16
ANXA1 and the risk for early-onset Parkinson's disease	16
Editorial Advisory Board	16
Decreased pH in the aging brain and Alzheimer's disease	16
Healthy dietary intake moderates the effects of age on brain iron concentration and working memory performance	16
APOE4 homozygote females are resistant to the beneficial effects of 17β-estradiol on memory and CA1 dendritic spine density in the EFAD mouse model of Alzheimer's disease	16
Contents	16
Mutation analysis of the ECE1 gene in late-onset Alzheimer’s disease	16
Unique regional patterns of amyloid burden predict progression to prodromal and clinical stages of Alzheimer's disease	16
Blood-brain barrier water permeability across the adult lifespan: A multi-echo ASL study	15
Genotype-phenotype correlation in Tunisian patients with Amyotrophic Lateral Sclerosis	15
Editorial Advisory Board	15
Editorial Advisory Board	15
Lower oddball event-related EEG delta and theta responses in patients with dementia due to Parkinson's and Lewy body than Alzheimer's disease	15
The links among age, sex, and glutathione: A cross-sectional magnetic resonance spectroscopy study	15
Free water-corrected fractional anisotropy of the fornix and parahippocampal cingulum predicts longitudinal memory change in cognitively healthy older adults	15
Neuropathologic correlates of cerebral microbleeds in community-based older adults	15
The effects of age bias on neural correlates of successful and unsuccessful response inhibition in younger and older adults	15
Contents Continued	15
Contents Continued	15
Depressive symptoms are associated with reduced positivity preferences in episodic memory in aging	15
Signatures for viral infection and inflammation in the proximal olfactory system in familial Alzheimer's disease	15
CSF peptides from VGF and other markers enhance prediction of MCI to AD progression using the ATN framework	15
Age differences in the neural correlates of recollection: transient versus sustained fMRI effects	15
Commentary on "A framework for concepts of reserve and resilience in aging"	15
Contents Continued	15
Contents	15
Associations of brain morphology with cortical proteins of cognitive resilience	15
Neural correlates of metacognition across the adult lifespan	15
Degeneration in Nucleus basalis of Meynert signals earliest stage of Alzheimer’s disease progression	14
Shared and oppositely regulated transcriptomic signatures in Huntington's disease and brain ischemia confirm known and unveil novel potential neuroprotective genes	14
Functional variant rs17525453 within RAB35 gene promoter is possibly associated with increased risk of Parkinson's disease in Taiwanese population.	14
White matter hyperintensity volume modifies the association between CSF vascular inflammatory biomarkers and regional FDG-PET along the Alzheimer’s disease continuum	14
Contents	14
Contents Continued	14
Contents Continued	14
Generating diagnostic profiles of cognitive decline and dementia using magnetoencephalography	14
Cognitive reserve proxies are associated with age-related cognitive decline – Not age-related gait speed decline	14

Alcohol consumption confers lasting impacts on prefrontal cortical neuron intrinsic excitability and spontaneous neurotransmitter signaling in the aging brain in mice	14
Lifelong experiences as a proxy of cognitive reserve moderate the association between connectivity and cognition in Alzheimer's disease	14
Dynamic interplay of frontoparietal cholinergic innervation and cortical reorganization in the regulation of attentional capacities in aging	14
Contents	14
Lack of limbic-predominant age-related TDP-43 encephalopathy (LATE) neuropathological changes in aged macaques with memory impairment	14
Assessment of ANG variants in Parkinson's disease	14
Genetic and clinical characteristics of ALS patients with NEK1 gene variants	14
Matrix metalloproteinases are associated with brain atrophy in cognitively unimpaired individuals	14
Cortical network modularity changes along the course of frontotemporal and Alzheimer's dementing diseases	14
Age-related neuroinflammation and pathology in the locus coeruleus and hippocampus: beta-adrenergic antagonists exacerbate impairment of learning and memory in aged mice	14
Loss of SST and PV positive interneurons in the ventral hippocampus results in anxiety-like behavior in 5xFAD mice	14
Re-analysis of the Hungarian amyotrophic lateral sclerosis population and evaluation of novel ALS genetic risk variants	14
Amyloid- β and tau deposition influences cognitive and functional decline in Down syndrome	13
Impact of thyroid hormone perturbations in adult mice: brain weight and blood vessel changes, gene expression variation, and neurobehavioral outcomes	13
Study of Alzheimer's disease- and frontotemporal dementia-associated genes in the Cretan Aging Cohort	13
Age-related similarities and differences in cognitive and neural processing revealed by task-related microstate analysis	13
Tau in the brain interstitial fluid is fragmented and seeding–competent	13
Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer's disease	13
Brain structural indicators of β-amyloid neuropathology	13
NPC1 variants are not associated with Parkinson’s disease, REM-sleep behavior disorder or dementia with Lewy bodies in European cohorts	13
Editorial Advisory Board	13
The shared genetic architecture of modifiable risk for Alzheimer's disease: a genomic structural equation modelling study	13
The basal forebrain volume reduction detected by MRI does not necessarily link with the cholinergic neuronal loss in the Alzheimer's disease mouse model	13
Corrigendum to “Dissemination in time and space in presymptomatic granulin mutation carriers: A spatial chronnectome study” [Neurobiology of Aging Volume 108, December 2021, Pages 155–167]	13
A ketogenic intervention improves dorsal attention network functional and structural connectivity in mild cognitive impairment	13
Associations between phasic arousal and decisions under risk in younger and older adults	13
DKI enhances the sensitivity and interpretability of age-related DTI patterns in the white matter of UK biobank participants	13
Editorial Advisory Board	13
CSF phosphorylated tau as an indicator of subsequent tau accumulation	13
Brain reserve in midlife is associated with executive function changes across 12 years	13
Engram reactivation during memory retrieval predicts long-term memory performance in aged mice	13
Brain age and Alzheimer's-like atrophy are domain-specific predictors of cognitive impairment in Parkinson's disease	13
Aging of gray matter microstructure: A brain-wide characterization of age group differences using NODDI	12
RETRACTED: Age-related declines in neural selectivity manifest differentially during encoding and recognition	12
Hippocampal atrophy over two years in relation to tau, amyloid-β and memory in older adults	12
Hypothalamic MRI-derived microstructure is associated with neurocognitive aging in humans	12
Editorial Advisory Board	12
Analysis of NOTCH2NLC GGC repeat expansion in Taiwanese patients with amyotrophic lateral sclerosis	12
Gene-based burden analysis of damaging private variants in PRKN, PARK7 and PINK1 in Parkinson's disease cohorts of European descent	12
Preventive effect of propolis on cognitive decline in Alzheimer’s disease model mice	12
Predicting future cognitive decline from non-brain and multimodal brain imaging data in healthy and pathological aging	12
Contents Continued	12
Moderating effects of cognitive reserve on the relationship between brain structure and cognitive abilities in middle-aged and older adults	12
Contents	12
The relationship of glucose-stimulated insulin secretion to cerebral glucose metabolism and cognition in healthy middle-aged and older adults	12
Operationally defining cognitive reserve genes	12
Identification and functional characterization of novel variants of MAPT and GRN in Chinese patients with frontotemporal dementia	11
A novel presenilin 1 duplication mutation (Ile168dup) causing Alzheimer's disease associated with myoclonus, seizures and pyramidal features	11
Absence of coding somatic single nucleotide variants within well-known candidate genes in late-onset sporadic Alzheimer's Disease based on the analysis of multi-omics data	11
Beyond group classification: Probabilistic differential diagnosis of frontotemporal dementia and Alzheimer’s disease with MRI and CSF biomarkers	11
Editorial Advisory Board	11
Aging induces abnormal accumulation of Aβ in extracellular vesicle and/or intraluminal membrane vesicle-rich fractions in nonhuman primate brain	11
Older adults with reduced cerebrovascular reactivity exhibit high white matter hyperintensity burden	11
Extracellular matrix proteoglycans support aged hippocampus networks: a potential cellular-level mechanism of brain reserve	11
Heterogenous response to aging of astrocytes in murine Substantia Nigra pars compacta and pars reticulata	11
Relationship between cortical brain atrophy, delirium, and long-term cognitive decline in older surgical patients	11
Longitudinal associations of absolute versus relative moderate-to-vigorous physical activity with brain microstructural decline in aging	11
Mutation analysis of the GLA gene in Chinese patients with intracerebral hemorrhage	11
Age-related dedifferentiation and hyperdifferentiation of perceptual and mnemonic representations	11
Contents Continued	11
Sulcal morphology as cognitive decline predictor in older adults with memory complaints	11
Aging induces cell loss and a decline in phagosome processing in the mouse retinal pigment epithelium	11
A genome-wide association study of plasma phosphorylated tau181	11
Contents Continued	11
Flexibility as a marker of early cognitive decline in humanized apolipoprotein E ε4 (ApoE4) mice	11
Neural atrophy produced by AAV tau injections into hippocampus and anterior cortex of middle-aged mice	11
Exploring graded profiles of hippocampal atrophy along the anterior-posterior axis in semantic dementia and Alzheimer’s disease	11
Early low-dose ghrelin intervention via miniosmotic pumps could protect against the progressive dopaminergic neuron loss in Parkinson's disease mice	11
Neuronal hyperexcitability in the Tg2576 mouse model of Alzheimer's disease – the influence of sleep and noradrenergic transmission	11
Corrigendum to “Longitudinal characterization of neuroanatomical changes in the Fischer 344 rat brain during normal aging and between sexes [neurobiology of aging. 109 (2022) 216–228]”	11
Auditory robustness and resilience in the aging auditory system of the desert locust	11
Myelin, aging, and physical exercise	11
C-reactive protein and risk of Alzheimer's disease	11
Resting state electroencephalographic alpha rhythms are sensitive to Alzheimer’s disease mild cognitive impairment progression at a 6-month follow-up	11
Multimodal investigation of neuropathology and neurometabolites in mild cognitive impairment and late-life depression with 11C-PiB beta-amyloid PET and 7T magnetic resonance spectroscopy	11