OOIR: Observatory of International Research

Papers

(The TQCC of Peptides is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Transcardiac gradients of pro-cholecystokinin, cholecystokinin, and gastrin in patients with and without heart failure with reduced ejection fraction	106
Corrigendum to “Oxytocin attenuates cardiac hypertrophy by improving cardiac glucose metabolism and regulating OXTR/JAK2/STAT3 axis” [Peptides 182 (2024) 171323]	85
Editorial Board	82
Editorial Board	44
KNDy neurons as the GnRH pulse generator: Recent studies in ruminants	39
Serum alanine transaminase is predictive of fasting and postprandial insulin and glucagon concentrations in type 2 diabetes	39
The first structure-activity relationship study of oxytocin as a positive allosteric modulator for the µ opioid receptor	37
PCP consensus protein/peptide alphavirus antigens stimulate broad spectrum neutralizing antibodies	36
The present and future of synthetic orexin receptor agonists	33
Emerging roles of oxyntomodulin-based glucagon-like peptide-1/glucagon co-agonist analogs in diabetes and obesity	32
Natriuretic peptides potentiate cardiac hypertrophic response to noradrenaline in rats	31
Angiotensin-(1−7), a protective peptide against vascular aging	27
Desacyl-ghrelin, not just an inactive form of ghrelin? A review of current knowledge on the biological actions of desacyl-ghrelin	26
Minimum biological domain of xenin-25 required to induce anion secretion in the rat ileum	25
Gut hormone analogues and skeletal health in diabetes and obesity: Evidence from preclinical models	24
Nesfatin-1 regulates steroidogenesis in mouse Leydig cells	24
The antimicrobial peptide Abaecin alleviates colitis in mice by regulating inflammatory signaling pathways and intestinal microbial composition	24
Localization and expression of Orexin B (OXB) and its type 2 receptor (OX2R) in mouse testis during postnatal development	23
The impact of multifunctional enkephalin analogs and morphine on the protein changes in crude membrane fractions isolated from the rat brain cortex and hippocampus	23
Peptides and primate personality: Central and peripheral oxytocin and vasopressin levels and social behavior in two baboon species (Papio hamadryas and Papio anubis)	23
Editorial Board	22
Asprosin-mediated regulation of ovarian functions in mice: An age-dependent study	21
Studies on the in vitro mechanism and in vivo therapeutic effect of the antimicrobial peptide ACP5 against Trichophyton mentagrophytes	21
Editorial Board	21
Effect of Fc-Elabela-21 on renal ischemia/reperfusion injury in mice: Mediation of anti-apoptotic effect via Akt phosphorylation	21

Editorial Board	20
Suppression of B-type natriuretic peptide gene expression in cardiomyocytes under anoxic conditions	19
Synthesis, conformation and cytotoxic activity of short hybrid peptides containing conformationally constrained 1-(aminomethyl)cyclohexanecarboxylic acid and gabapentin	19
Impact of galanin receptors 2 and 3 double-knockout on neuroinflammation and functional recovery following traumatic brain injury	19
VR-10 polypeptide interacts with CD36 to induce cell apoptosis and autophagy in choroid-retinal endothelial cells: Identification of VR-10 as putative novel therapeutic agent for choroid neovasculariz	18
GIP-derived GIP receptor antagonists – a review of their role in GIP receptor pharmacology	18
Endogenous opiates and behavior: 2024	18
Glucagon-like peptide-1 receptor promotes osteoblast differentiation of dental pulp stem cells and bone formation in a zebrafish scale regeneration model	18
Modulatory role of neuropeptide FF system in macrophages	18
Editorial Board	17
Lasso peptides realm: Insights and applications	17
Dysfunction of the renin-angiotensin-aldosterone system in human septic shock	17
Dulaglutide accelerates diabetic wound healing by suppressing Nrf2-dependent ferroptosis in diabetic mice	17
Special issue on Invertebrate Peptides	16
JHP-7 (QLLEELKR), a heptapeptide derived from Jinhua ham, may ameliorate intrauterine adhesion (IUA) via inhibiting inflammatory response and apoptosis	16
Allatotropin (AT) related peptides L-ATRP and D2-ATRP diastereomers activate an endogenous receptor and suppress heart rate in the Pacific abalone Haliotis discus hannai	16
Jan Fahrenkrug (6/6 1947 – 10/11 2021)	15
Inhibitors of the MAPK/ NF-κB pathway attenuate the upregulation of the ETB receptor mediated by high glucose in vascular smooth muscle cells	15
Simplified drug efficacy evaluation system for vasopressin neurodegenerative disease using mouse disease-specific induced pluripotent stem cells	14
Endogenous opiates and behavior: 2023	14
Glucagon and energy expenditure; Revisiting amino acid metabolism and implications for weight loss therapy	14
The intricate relationship between circadian rhythms and gastrointestinal peptides in obesity	14
Significance of D- tryptophan in Contryphan-Ar1131 Conus peptide: Oxidative folding, trypsin binding, and photostabilization activity	14
The role of leptin and ghrelin in the regulation of appetite in obesity	14
A novel endomorphin-2/salmon calcitonin hybrid peptide with enhancing anti-allodynic and anti-anxiety effects	14
Erythropoietin attenuates lead-induced spatial memory deficits and anxiety-like behavior by suppressing hippocampal oxidative stress, cell death inhibition, and inflammation reduction	14
Recombinant production of isotope-labeled human α-defensin 5 via calmodulin fusion and insights into its expression enhancement	14
Influence of the angiotensin-(1−7) on the vascular effects of the endothelin-1 in normotensive and hypertensive rats	14
Peptides as mediators of stress responses	13
The T-1 conotoxin μ-SrVA from the worm hunting marine snail Conus spurius preferentially blocks the human NaV1.5 channel	13
Glucagon-based therapy for people with diabetes and obesity: What is the sweet spot?	13
Targeting the GLP-2 receptor in the management of obesity	13
Reduced plasma cortistatin is related to clinical parameters in patients with essential hypertension	13
PACAP inhibits sepsis-associated acute lung injury by inhibiting the Sp1/AQP1 pathway	13
Investigation of irisin's role in pubertal onset physiology in female rats	13
Venomous gland transcriptome and venom proteomic analysis of the scorpion Androctonus amoreuxi reveal new peptides with anti-SARS-CoV-2 activity	13
Editorial Board	13
Synthesis of potent antagonists of receptors for growth hormone-releasing hormone with antitumor and anti-inflammatory activity	13
Development of a glucagon sensitivity test in humans: Pilot data and the GLUSENTIC study protocol	13
Body weight modulates the impact of oxytocin on chronic cold-immobilization stress response	12
Editorial: Special issue novel aspects of islet peptides	12
Liraglutide suppresses ferroptosis by upregulation NRF2 in type 2 diabetic cardiomyopathy	12
Effectiveness of analog of Humanin in ameliorating streptozotocin-induced diabetic nephropathy in Sprague Dawley rats	12
Corrigendum to “Liraglutide inhibited AGEs induced coronary smooth muscle cell phenotypic transition through inhibiting the NF-κB signal pathway” [Peptides 112 (2019) 125–132]	12
The apelin-apela receptor APJ is necessary for formation and healing of ischemia reperfusion-induced gastric ulcer in rats	12
Effect of pregnancy on the expression of nutrient-sensors and satiety hormones in mice	12
Semaglutide early intervention attenuated testicular dysfunction by targeting the GLP-1–PPAR-α–Kisspeptin–Steroidogenesis signaling pathway in a testicular ischemia-reperfusion rat model	11
Urocortin3: Local inducer of somatostatin release and bellwether of beta cell maturity	11
Role of brain NUCB2/nesfatin-1 in stress and stress-related gastrointestinal disorders	11
Alamandine attenuates oxidative stress in the right carotid following transverse aortic constriction in mice	11

Egg white-derived peptide KPHAEVVLR promotes wound healing in rat palatal mucosa via PI3K/AKT/mTOR pathway	11
The effects of corticotropin-releasing factor (CRF) and urocortins on the noradrenaline (NA) released from the locus coeruleus (LC)	11
The non-cardiovascular actions of ACE	11
Neuropeptides affecting social behavior in mammals: Oxytocin	11
Spexin expression in the human bile duct and perihilar cholangiocarcinoma	11
Estrogens impair hypophagia and hypothalamic cell activation induced by vasoactive intestinal peptide, but not by pituitary adenylate cyclase-activating polypeptide	11
GLP-1 and GIP receptor signaling in beta cells – A review of receptor interactions and co-stimulation	11
FGF4 alleviates renal injury caused by ischemia-reperfusion(I/R) by inhibiting ferroptosis and pyroptosis	10
Corticotropin-releasing factor receptor 1 (CRF-R1) antagonists: Promising agents to prevent visceral hypersensitivity in irritable bowel syndrome	10
Editorial Board	10
Angiotensin-(1−7) attenuates the negative inotropic response to acetylcholine in the heart	10
Angiotensin-(1-7) reduces doxorubicin-induced aortic arch dysfunction in male and female juvenile Sprague Dawley rats through pleiotropic mechanisms	10
Synergistic interaction between DAMGO-NH2 and NOP01 in peripherally acting antinociception in two mouse models of formalin pain	10
Recent articles highlighting the multifunctional character and wider therapeutic potential of antimicrobial peptides	10
Characterization of rice endosperm-derived antidepressant-like peptide (REAP): An orally active novel tridecapeptide derived from rice protein	10
Maximizing cost savings in heart failure management: The economic value of natriuretic peptide testing	10
In memoriam: Dr. Stephen Tobe (11 October 1944 – 31 December 2020)	10
Editorial Board	10
Irisin alleviates hyperoxia-induced bronchopulmonary dysplasia through activation of Nrf2/HO-1 pathway	10
Editorial Board	9
Protective effects of PACAP against high glucose-induced inflammation on air-liquid interface corneal epithelium barrier	9
Nesfatin-1 is involved in hyperbaric oxygen-mediated therapeutic effects in high fat diet-induced hyperphagia in mice	9
Interleukin-6, undercarboxylated osteocalcin, and brain-derived neurotrophic factor responses to single and repeated sessions of high-intensity interval exercise	9
Engineering a potent and long-acting GLP-1/Y2 receptor dual agonist as a multi-agonist therapy for diabetes and obesity	9
Irisin prevents hypoxic-ischemic brain damage in rats by inhibiting oxidative stress and protecting the blood-brain barrier	9
AT2 receptor agonist LP2 restores respiratory function in a rat model of bleomycin-induced lung remodelling	9
Structure and function of neurohypophysial hormones	9
Role of sexually dimorphic oxytocin receptor-expressing neurons in the anteroventral periventricular nucleus on maternal behavior	9
GLP-1 receptor agonism and GIP receptor antagonism induce substantial alterations in enteroendocrine and islet cell populations in obese high fat fed mice	9
Involvement of relaxin-family peptide-3 receptor (RXFP3) in the ventral dentate gyrus of the hippocampus in spatial and fear memory in rats	8
A short framework-III (mini-M-2) conotoxin from the venom of a vermivorous species, Conus archon, inhibits human neuronal nicotinic acetylcholine receptors	8
Host defense peptides at the crossroad of endothelial cell physiology: Insight into mechanistic and pharmacological implications	8
PD1 CD44 antiviral peptide as an inhibitor of the protein-protein interaction in dengue virus invasion	8
Functional role of immunoglobulin G as an oxytocin-carrier protein	8
Discovery of the bioactive form of glucagon-like peptide-1: An attempt to correct some misconceptions	8
The impact of GLP-1 signalling on the energy metabolism of pancreatic islet β-cells and extrapancreatic tissues	8
History of peptide research: Ulf Svante von Euler's last visit to Yugoslavia	7
Amphibian host-defense peptides with potential for Type 2 diabetes therapy – an updated review	7
Antiosteoporosis effects of a marine antimicrobial peptide pardaxin via regulation of the osteogenesis pathway	7
Evaluation of plasma arginine vasopressin during hypertonic saline loading: A comparison of radioimmunoassay and liquid chromatography–tandem mass spectrometry	7
Neprilysin deficiency reduces hepatic gluconeogenesis in high fat-fed mice	7
Diminazene Aceturate, an angiotensin converting enzyme 2 (ACE2) activator, promotes cardioprotection in ischemia/reperfusion-induced cardiac injury	7
Mitochondrial-derived peptides: Antidiabetic functions and evolutionary perspectives	7
Cbf-14, a cationic peptide derived from cathelin-domain, exhibits anti-inflammation activity via inhibiting PI3K- Akt /ROS/ NF-κB signaling pathway	7
LP2, a cyclic angiotensin-(1−7) analog extended with an N-terminal D-lysine, impairs growth of patient-derived xenografts of colorectal carcinoma in mice	7
Optogenetics studies of kisspeptin neurons	7
Peptides in the regulation of glucagon secretion	7
Adropin: A cardio-metabolic hormone in the periphery, a neurohormone in the brain?	7
Gluco-metabolic response to exogenous oxytocin in totally pancreatectomized patients and healthy individuals	7
Abba J. Kastin – Tribute to the founding and honorary editor of PEPTIDES	7
Development of antimicrobial peptides as a strategy for infectious disease control	7
Acute effects of peripherally administered nicotine on food intake via the central anorectic peptide nesfatin-1/nucleobindin-2 in adult male rats	7
Heart peptides and HFpEF (heart failure with preserved ejection fraction)	7
Post-prandial secretion of glucagon-like peptide-2 (GLP-2) after carbohydrate-, fat- or protein enriched meals in healthy subjects	7
Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway	7