OOIR: Observatory of International Research

Papers

(The TQCC of Lasers in Surgery and Medicine is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Energy‐based devices for the treatment of Acne Scars: 2022 International consensus recommendations	41
Deep Learning in Biomedical Optics	38
Fractional 1064 nm Picosecond Laser in Treatment of Melasma and Skin Rejuvenation in Asians, A Prospective Study	36
Strategies to Improve the Antimicrobial Efficacy of Photodynamic, Sonodynamic, and Sonophotodynamic Therapies	34
Stone ablation rates using innovative pulse modulation technology: Vapor tunnel, virtual basket, and bubble blast. An in vitro experimental study	21
Application of OCT‐Derived Attenuation Coefficient in Acute Burn‐Damaged Skin	20
Objective and Long‐Term Evaluation of the Efficacy and Safety of a 1064‐nm Picosecond Laser With Fractionated Microlens Array for the Treatment of Atrophic Acne Scar in Asians	18
Evaluating the effectiveness and safety of radiofrequency for face and neck rejuvenation: A systematic review	16
Treatment of melasma with a low‐fluence 1064 nm Q‐switched Nd:YAG laser: Laser toning in Caucasian women	15
Combining Nd:YAG laser with optical coherence tomography for nonsurgical treatment of basal cell carcinoma	15
Comparison of Fractional Micro‐Plasma Radiofrequency and Fractional Microneedle Radiofrequency for the Treatment of Atrophic Acne Scars: A Pilot Randomized Split‐Face Clinical Study in China	15
Reflectance Confocal Microscopy, Optical Coherence Tomography, and Multiphoton Microscopy in Inflammatory Skin Disease Diagnosis	15
Safety and efficacy of endovenous laser ablation (EVLA) using 1940 nm and radial emitting fiber: 3‐year results of a prospective, non‐randomized study and comparison with 1470 nm	14
Scattering‐Based Light‐Sheet Microscopy for Rapid Cellular Imaging of Fresh Tissue	14
Incident Fluence Analysis for 755‐nm Picosecond Laser Treatment of Pigmented Skin Lesions Based on Threshold Fluences for Melanosome Disruption	14
Topical 0.5% Timolol Maleate Significantly Enhances Skin‐Barrier Restoration After Fractional Carbon Dioxide Laser Treatment for Acne Scars	13
The Fractional CO₂ Laser for the Treatment of Genitourinary Syndrome of Menopause: A Prospective Multicenter Cohort Study	13
Wound Healing Profile After 1064‐ and 532‐nm Picosecond Lasers With Microlens Array of In Vivo Human Skin	13
The state of the art of biomedical applications of optogenetics	13
Modified 5‐aminolevulinic acid photodynamic therapy reduces pain and improves therapeutic effects in cutaneous squamous cell carcinoma mouse model	13
Non‐Ablative 1927 nm Fractional Thulium Fiber Laser: New, Promising Treatment Modality for Riehl's Melanosis	13
A 12‐Week, Prospective, Non‐Comparative, Non‐Randomized Study of Magnetic Muscle Stimulation for Improvement of Body Satisfaction With the Abdomen and Buttocks	13
Clinical and histologic evaluation of a fractional radiofrequency treatment of wrinkles and skin texture with novel 1‐mm long ultra‐thin electrode pins	13
Management of oral leukoplakia by ablative fractional laser‐assisted photodynamic therapy: A 3‐year retrospective study of 48 patients	12
Novel Application of the 730 and 785 nm Picosecond Titanium Sapphire Lasers for the Treatment of Nevus of Ota	12

Combined Low‐Dose Isotretinoin and Pulsed Dye Laser Versus standard‐Dose Isotretinoin in the Treatment of Inflammatory Acne	12
Treatment of facial and non‐facial lentigines with a 730 nm picosecond titanium: Sapphire laser is safe and effective	12
Vascularity and Thickness Changes in Immature Hypertrophic Scars Treated With a Pulsed Dye Laser	12
Comparison of 1064‐nm and Dual‐Wavelength (532/1064‐nm) Picosecond‐Domain Nd:YAG Lasers in the Treatment of Facial Photoaging: A Randomized Controlled Split‐Face Study	11
Improvement in the appearance of cellulite and skin laxity resulting from a single treatment with acoustic subcision: Findings from a multicenter pivotal clinical trial	11
Safety and efficacy of fractional radiofrequency for the treatment and reduction of acne scarring: A prospective study	11
A Randomized Controlled Pilot Study: Combined 595‐nm Pulsed Dye Laser Treatment and Oxymetazoline Hydrochloride Topical Cream Superior to Oxymetazoline Hydrochloride Cream for Erythematotelangiectatic	11
Adverse Events of Intense Pulsed Light Combined With Meibomian Gland Expression Versus Meibomian Gland Expression in the Treatment of Meibomian Gland Dysfunction	11
Photobiomodulation Response From 660 nm is Different and More Durable Than That From 980 nm	11
The efficacy and safety of low‐energy carbon dioxide fractional laser use in the treatment of early‐stage pediatric hypertrophic scars: A prospective, randomized, split‐scar study	11
Fractional Carbon Dioxide Laser Versus Carboxytherapy in Treatment of Striae Distensae	11
Low‐Level Light Therapy Downregulates Scalp Inflammatory Biomarkers in Men With Androgenetic Alopecia and Boosts Minoxidil 2% to Bring a Sustainable Hair Regrowth Activity	11
Identification of oral precancerous and cancerous tissue by swept source optical coherence tomography	11
Dynamic Optical Coherence Tomography of Cutaneous Blood Vessels in Melasma and Vessel Response to Oral Tranexamic Acid	10
Single Treatment Protocol With Microneedle Fractional Radiofrequency for Treatment of Body Skin Laxity and Fat Deposits	10
The Efficacy and Safety of Fractional 1064 nm Nd:YAG Picosecond Laser Combined With Intense Pulsed Light in the Treatment of Atrophic Acne Scar: A Split‐Face Study	10
Laser‐Assisted Hyaluronic Acid Delivery by Fractional Carbon Dioxide Laser in Facial Skin Remodeling: A Prospective Randomized Split‐Face Study in France	10
Efficacy and Safety of Topical Silymarin Versus Low Fluence 1064‐nm Q Switched Nd:YAG Laser in the Treatment of Melasma: A Comparative Randomized Trial	10
Combinatory Effect of ALA‐PDT and Itraconazole Treatment for Trichosporon asahii	10
Optical Coherence Tomography‐Assisted Evaluation of Fractional Er:YAG Laser Versus Fractional Microneedling Radiofrequency in Treating Striae Alba	10
Efficacy and safety of laser‐assisted combination chemotherapy: A follow‐up study of treatment with 5‐fluorouracil and cisplatin for basal cell carcinoma	10
Skin of color representation in cosmetic clinical trials: A literature review	10
Stem cell‐derived exosomes in the treatment of melasma and its percutaneous penetration	10
Improved healing and macrophage polarization in oral ulcers treated with photobiomodulation (PBM)	10
Quantitative assessment of the long‐term efficacy and safety of a 1064‐nm picosecond laser with fractionated microlens array in the treatment of enlarged pores in Asians: A case‐control study	10
OCT‐Based Angiography and Surface Topography in Burn‐Damaged Skin	10
A Comparison of Human and Porcine Skin in Laser‐Assisted Drug Delivery of Chemotherapeutics	10
Characteristics of Non‐Ablative Resurfacing of Soft Tissues by Repetitive Er:YAG Laser Pulse Irradiation	10
Efficacy of Photodynamic Anti‐Microbial Chemotherapy for Acanthamoeba Keratitis In Vivo	10
Treatment of periorbital wrinkles using thermo‐mechanical fractional injury therapy versus fractional non‐ablative 1565 nm laser: A comparative prospective, randomized, double‐arm, controlled study	10
Effects of Pulsed‐Wave Photobiomodulation Therapy on Human Spermatozoa	10
Analysis of port‐wine birthmark vascular characteristics by location: Utility of optical coherence tomography mapping	9
Veno‐venous extracorporeal blood phototherapy increases the rate of carbon monoxide (CO) elimination in CO‐poisoned pigs	9
Combination of a 755‐nm picosecond laser and hydroquinone 2% cream versus hydroquinone 2% cream alone for the treatment of melasma: A randomized, split‐face, and controlled trial	9
Fabrication and characterization of chitosan nanoparticles using the coffee‐ring effect for photodynamic therapy	9
Safety and Efficacy of Nano‐Pulse Stimulation Treatment of Non‐Genital, Cutaneous Warts (Verrucae)	9
Selective Cryolysis of Melanocytes: Critical Temperature and Exposure Time to Induce Selective Pigmentary Loss in Yucatan Pig Skin	9
Determination of Optimal Separation Times for Dual‐Pulse SWEEPS Laser‐Assisted Irrigation in Different Endodontic Access Cavities	9
Photodetection and Safety of 5‐Aminolevulinic Acid‐Induced Porphyrin in Patients With Cervical Intraepithelial Neoplasia	9
Tumor Clearance and Immune Cell Recruitment in UV‐Induced Murine Squamous Cell Carcinoma Exposed to Ablative Fractional Laser and Imiquimod Treatment	9
Fluorescence kinetics study of twice laser irradiation based HpD‐PDT for nonmelanoma skin cancer	9
Clinical endpoints of needle‐free jet injector treatment: An in depth understanding of immediate skin responses	9
Photobiomodulation Therapy on Myocardial Infarction in Rats: Transcriptional and Posttranscriptional Implications to Cardiac Remodeling	9
Photobiomodulation therapy for the prevention of acute radiation dermatitis in breast cancer patients undergoing hypofractioned whole‐breast irradiation (LABRA trial)	9
Does the Time of Onset of Urinary Symptoms Affect Microablative Fractional CO₂ Laser Efficacy in Postmenopausal Women?	9
Histological Characteristics of Skin Treated With a Fractionated 1064‐nm Nd: YAG Picosecond Laser With Holographic Optics	8
High‐contrast visualization of human skin cancers with combined reflectance confocal and moxifloxacin‐based two‐photon microscopy: An ex vivo study	8
Photobiomodulation therapy mitigates cardiovascular aging and improves survival	8
Three‐Year Results of Facial Photoaging in Asian Patients After Alexandrite 755 nm Picosecond Laser With Diffractive Lens Array: A Split‐Face, Single‐Blinded, Randomized Controlled Comparison	8
Picosecond Laser treatment of Striae Distensae: In vivo Evaluation of Results by 3D Analysis, Reflectance Confocal Microscopy, and Patient′s Satisfaction	8

Thermo‐Mechanical Fractional Injury Therapy for Facial Skin Rejuvenation in Skin Types II to V: A Retrospective Double‐Center Chart Review	8
High Contrast Reflectance Imaging of Enamel Demineralization and Remineralization at 1950‐nm for the Assessment of Lesion Activity	8
Efficacy of Minoxidil Combined With Photobiomodulation for the Treatment of Male Androgenetic Alopecia. A Double‐Blind Half‐Head Controlled Trial	8
The Effect of Intense Pulsed Light on the Skin Microbiota and Epidermal Barrier in Patients with Mild to Moderate Acne Vulgaris	8
Treatment of abdominal striae distensae in Fitzpatrick skin types IV to V using a 1064‐nm picosecond laser with a fractionated microlens array	8
Assessment of natural antioxidants' effect on PDT cytotoxicity through fluorescence microscopy image analysis	8
A Clinical Perspective on the Automated Analysis of Reflectance Confocal Microscopy in Dermatology	8
Combining Low Power Fractional CO₂ With QS‐NdYAG Toning in the Treatment of Melasma Reduces the Incidence of Punctate Leukoderma	8
Hybrid fractional laser treatment for photodamaged facial skin rejuvenation 6 years following fractional CO₂: Comparison of clinical outcome and patients' satisfaction	7
Control of Burn Wound Infection by Methylene Blue‐Mediated Photodynamic Treatment With Light‐Emitting Diode Array Illumination in Rats	7
Photobiomodulation with polychromatic light (600–1200 nm) improves fat graft survival by increasing adipocyte viability, neovascularization, and reducing inflammation in a rat model	7
Photo‐mediated ultrasound therapy for the treatment of retinal neovascularization in rabbit eyes	7
Photobiomodulation therapy's effects on cardiac fibrosis activation after experimental myocardial infarction	7
Vaginal Fractional Carbon Dioxide Laser Treatment and Changes in Vaginal Biomechanical Parameters	7
Effect of Optimized Irrigation With Photon‐Induced Photoacoustic Streaming on Smear Layer Removal, Dentin Microhardness, Attachment Morphology, and Survival of the Stem Cells of Apical Papilla	7
Treatment of burn hypertrophic scar with fractional ablative laser‐assisted drug delivery can decrease levels of hyperpigmentation	7
Pathological Changes in Axillary Hyperhidrosis and Axillary Osmidrosis Induced by Microwave Treatment: Comparison of Single‐ and Double‐Pass Irradiation	7
Demineralization Inhibition by High‐Speed Scanning of 9.3 µm CO ₂ Single Laser Pulses Over Enamel	7
Treatment of nail psoriasis with pulsed dye laser versus combined pulsed dye and Nd:YAG lasers—An intrapatient left‐to‐right study	7
Development of a Predictive Monte Carlo Radiative Transfer Model for Ablative Fractional Skin Lasers	6
Automated Extraction of Skin Wound Healing Biomarkers From In Vivo Label‐Free Multiphoton Microscopy Using Convolutional Neural Networks	6
Combined CO₂ and dye laser technique in the treatment of outcomes due to flap necrosis after surgery for basal cell carcinoma on the nose	6
Measurements of hair temperature avalanche effect with alexandrite and Nd:YAG hair removal lasers	6
Efficacy and safety of picosecond 755‐nm alexandrite laser for treatment of nevus of Ota in Taiwanese children: A retrospective study	6
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Effect of Artesunate Combined With Fractional CO₂ Laser on the Hypertrophic Scar in a Rabbit Model	6
Fractional CO₂ laser treatment as adjunctive therapy to topical steroids for managing vulvar lichen sclerosus	6
Relative perfusion index: An objective, quantitative and noninvasive method for evaluating the severity of keloids	6
ALA‐PDT regulates macrophage M1 polarization via ERK/MAPK‐NLRP3 pathway to promote the early inflammatory response	6
Beneficial Effects of Treatment With Low‐Fluence 755‐nm Q‐Switched Alexandrite Laser for Nevus of Ota	6
Differentiation of Brain Tumor Microvasculature From Normal Vessels Using Optical Coherence Angiography	6
Theoretical and in vivo investigations of morphology and concentration of gold nanoparticles for laser surgery	6
Hair Removal With Blended 755/1064 nm Laser Energy	6
Deep Learning‐Based Denoising in High‐Speed Portable Reflectance Confocal Microscopy	6
Photothermal therapy using gold nanoparticles and a long‐pulsed 755‐nm alexandrite laser to treat facial photoaging in Asian skin: A prospective clinical trial	6
On‐Site Laser Photobiomodulation Treatment of Crushed Muscle Due to Prolonged Pressure in Rats	5
Successful Treatment of Scalp Micropigmentation With 1064 nm Picosecond Nd:YAG Laser	5
Laser‐assisted drug delivery of synthetic alpha melanocyte stimulating hormone and L‐tyrosine leads to increased pigmentation area and expression of melanogenesis genes in a porcine hypertrophic scar	5
Utility of high‐resolution ultrasound in measuring subcutaneous fat thickness	5
Channel Interaction During Infrared Light Stimulation in the Cochlea	5
Dermatologic Scar Assessment With Stereoscopic Imaging and Digital Three‐Dimensional Models: A Validation Study	5
Procedure and results on lower face and neck rejuvenation using a temperature‐controlled bipolar fractional radiofrequency microneedling device	5
Abstracts	5
Comparison of the efficacy and safety of 308‐nm excimer laser with intralesional corticosteroids for the treatment of alopecia areata: A randomized controlled study	5
Light‐activated photosealing with human amniotic membrane strengthens bowel anastomosis in a hypotensive, trauma‐relevant swine model	5
Comparative study of 1064 nm nanosecond, 1064 nm picosecond, 755 nm, and 595 nm lasers for tattoo removal: An essential role by macrophage	5
Analysis of the Curative Effect of Alexandrite Laser in the Treatment of Venous Lake of Lips	5
Point‐of‐care devices based on fluorescence imaging and spectroscopy for tumor margin detection during breast cancer surgery: Towards breast conservation treatment	5
Fractional CO₂ laser ablation leads to enhanced permeation of a fluorescent dye in healthy and mycotic nails—An imaging investigation of laser–tissue effects and their impact on ungual drug	5
A Comparative Study Between Once‐Weekly and Alternating Twice‐Weekly Regimen Using Blue (470 nm) and Red (640 nm) Light Combination LED Phototherapy for Moderate‐to‐Severe Acne Vulgaris	5
Comparison of the efficacy and safety of a 730 nm picosecond titanium sapphire laser and a 755 nm picosecond alexandrite laser for the treatment of freckles in Asian patients: A two‐center randomized,	5
Single‐cell transcriptome analysis of fractional CO₂ laser efficiency in treating a mouse model of alopecia	5
Efficacy and safety of thermomechanical fractional injury‐assisted corticosteroid delivery versus intralesional corticosteroid injection for the treatment of hypertrophic scars: A randomized split‐sca	5
Combination Therapy for the Treatment of Complex Vascular Lesions	5
Assessment of adverse events for a home‐use intense pulsed light hair removal device using postmarketing surveillance	5
Repeated exposure to fractional CO₂ laser delays squamous cell carcinoma formation and prevents clinical and subclinical photodamage visualized by line‐field confocal optical coherence tomo	5
A pilot feasibility study to assess vascularity and perfusion of parathyroid glands using a portable hand‐held imager	5
Assessment of tissue‐specific changes in structure and function induced by in vivo skin/skull optical clearing techniques	4
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Extracorporeal membrane oxygenators with light‐diffusing fibers for treatment of carbon monoxide poisoning: Experiments, mathematical modeling, and performance assessment with unit cells	4
Quantitative investigation of laser ablation based on real‐time temperature variations and OCT images for laser treatment applications	4
Nondestructive optical feedback systems for use during infrared laser sealing of blood vessels	4
A prospective study to evaluate the treatment effect of pulsed dye laser on thyroidectomy hypertrophic scars using 3D imaging analysis	4
Assessment of a 3050/3200 nm fiber laser system for ablative fractional laser treatments in dermatology	4
FDA MAUDE database reported adverse events on noninvasive body contouring, cellulite treatment, and muscle stimulation from 2015 to 2021	4
Clinical and dermoscopic evaluation of melanocytic nevi changes during diode laser hair removal: A prospective study	4
High energy, double pass helium plasma dermal resurfacing: A prospective, multicenter, single‐arm clinical study	4
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Lateral image reconstruction of optical coherence tomography using one‐dimensional deep deconvolution network	4
Topical delivery of PD‐1 inhibitors with laser‐assisted passive diffusion and active intradermal injection: Investigation of cutaneous pharmacokinetics and biodistribution patterns	4
Optical, flow, and thermal analysis of a phototherapy extracorporeal membrane oxygenator for treating carbon monoxide poisoning	4
Treatment of Pain in Keloids Using Only a Long‐Pulsed 1064 nm Nd:YAG Laser	4
Cavitation and radiofrequency versus cryolipolysis on leptin regulation in central obese subjects: A randomized controlled study	4
Efficacy and safety of fractional 1064‐nm picosecond laser for atrophic traumatic and surgical scars: A randomized, single‐blinded, split‐scar‐controlled study	4
Multi‐Wavelength Photo‐Magnetic Imaging System for Photothermal Therapy Guidance	4
Real‐time laser speckle contrast imaging measurement during normothermic machine perfusion in pretransplant kidney assessment	4
Histopathological evaluation of the R134a multipulsed spray cooling assisted 1210 nm laser lipolysis by the murine model in vivo	4
Optical coherence tomography‐guided Nd:YAG laser treatment and follow‐up of basal cell carcinoma	4
Low‐fluence treatment with a novel fractionated 2,910‐nm fiber laser improves photodamage	4
Algorithmic approach to the treatment of solar lentigines with picosecond lasers	4

Patient selection criteria for percutaneous anterior cervical laser versus endoscopic discectomy	4
The Efficacy and Safety of a Variable Square Pulse (VSP) Erbium:YAG Laser for Treatment of Enlarged Pores in Asians	4
3D imaging of vascular anomalies using raster‐scanning optoacoustic mesoscopy	4
Long‐term improvement in the appearance of hypertrophic scars following a single treatment with acoustic subcision—A single center proof‐of‐concept study	4
Systemic vascular photobiomodulation accelerates the recovery of motor activity in rats following spinal cord injury	4
Fractional microneedle radiofrequency versus fractional carbon dioxide laser in the treatment of postburn hypertrophic scars	4
Assessing the Outcomes of Focused Heating of the Skin by a Long‐Pulsed 1064 nm Laser with an Integrated Scanner, Infrared Thermal Guidance, and Optical Coherence Tomography	4
A randomized split‐face comparative study of long‐pulsed alexandrite plus low‐fluence Nd:YAG laser versus pulsed‐dye laser in the treatment of rosacea	4
Light and energy‐based therapeutics for genitourinary applications: Consensus on protocols and best practices	4
Impact of microwave thermolysis energy levels on patient‐reported outcomes for axillary hyperhidrosis and osmidrosis	4
Hyperbaric phototherapy augments blood carbon monoxide removal	4
Needleless laser injector versus needle injection for skin enhancement and rejuvenation effect of dermal filler	4
Ablative fractional carbon dioxide laser improves quality of life in patients with extensive burn scars: A nested case–control study	4