American Journal of Physiology-Endocrinology and Metabolism

Article	Citations
A reduction of skeletal muscle DHA content does not result in impaired whole body glucose tolerance or skeletal muscle basal insulin signaling in otherwise healthy mice	82
The impact of glucagon to support postabsorptive glucose flux and glycemia in healthy rats and its attenuation in male Zucker diabetic fatty rats	81
Identification of newly synthetized proteins by mass spectrometry to understand palmitate-induced early cellular changes in pancreatic islets	78
Corrigendum for Zhang et al., volume 325, 2023, p. E363–E375	76
Comparison of an oral mixed meal plus arginine and intravenous glucose, GLP-1 plus arginine to unmask residual islet function in longstanding type 1 diabetes	76
Duodenal mucosal resurfacing with a GLP-1 receptor agonist increases postprandial unconjugated bile acids in patients with insulin-dependent type 2 diabetes	59
Mito-Mendelian interactions alter in vivo glucose metabolism and insulin sensitivity in healthy mice	44
Human liver afferent and efferent nerves revealed by 3-D/Airyscan super-resolution imaging	43
Mammary tumor development induces perturbation of liver glucose metabolism with inflammation and fibrosis	43
O-linked N-acetylglucosamine modification is essential for physiological adipose expansion induced by high-fat feeding	42
Transorgan short-chain fatty acid fluxes in the fasted and postprandial state in the pig	40
Human skeletal muscle methylome after low-carbohydrate energy-balanced exercise	38
Muscle damaging eccentric exercise attenuates disuse-induced declines in daily myofibrillar protein synthesis and transiently prevents muscle atrophy in healthy men	37
Persistent organic pollutants and β-cell toxicity: a comprehensive review	36
Evaluation of safety and effectiveness of NAD in different clinical conditions: a systematic review	34
A modest change in housing temperature alters whole body energy expenditure and adipocyte thermogenic capacity in mice	33
CB1Rs in VMH neurons regulate glucose homeostasis but not body weight	33
Three weeks of interrupting sitting lowers fasting glucose and glycemic variability, but not glucose tolerance, in free-living women and men with obesity	29
More than meets the islet: aligning nutrient and paracrine inputs with hormone secretion in health and disease	28
NADPH oxidase 4-derived hydrogen peroxide counterbalances testosterone-induced endothelial dysfunction and migration	27
α- or β-Adrenergic blockade does not affect transplanted islet cell responses to hypoglycemia in type 1 diabetes	27
Inhibition of protein kinase C-α and activation of ezrin by Lactobacillus acidophilus restore Na+/H+ exchange activity and fluid absorption in db/db mice	27
Phosphorylation of AS160-serine 704 is not essential for exercise-increase in insulin-stimulated glucose uptake by skeletal muscles from female or male rats	27
Higher protein intake during resistance training does not potentiate strength, but modulates gut microbiota, in middle-aged adults: a randomized control trial	26
Adaptive responses in uteroplacental metabolism and fetoplacental nutrient shuttling and sensing during placental insufficiency	26

Metabolic labeling unveils alterations in the turnover of HDL-associated proteins during diabetes progression in mice	26
Impact of the trans-ancestry polygenic risk score on type 2 diabetes risk, onset age and progression among population in Taiwan	25
Thrombospondin-1, CD47, and SIRPα display cell-specific molecular signatures in human islets and pancreata	25
Muscle fiber type-specific autophagy responses following an overnight fast and mixed meal ingestion in human skeletal muscle	24
In utero exposure to maternal diabetes exacerbates dietary sodium intake-induced endothelial dysfunction by activating cyclooxygenase 2-derived prostanoids	23
Epigenetic reprogramming of H3K4me3 in adipose-derived stem cells by HFS diet consumption leads to a disturbed transcriptomic profile in adipocytes	23
Saturated fat ingestion stimulates proatherogenic inflammation in polycystic ovary syndrome	23
Genetic ablation of the preptin-coding portion of Igf2 impairs pancreatic function in female mice	22
Neonatal IL-4 exposure decreases adipogenesis of male rats into adulthood	20
Metabolic shifts in ratio of ucOcn to cOcn toward bone resorption contribute to age-dependent bone loss in male mice	20
Synergistic effects of glucose tolerance and BMI on cardiovascular events and all-cause mortality in a healthy population: CA.ME.LI.A study 7 years follow-up	19
Adipocyte traits limiting cellular insulin responsiveness and glucose transport	19
Mechanisms of spinophilin-dependent pancreas dysregulation in obesity	19
Intestinal FFA3 mediates obesogenic effects in mice on a Western diet	19
Effects of acute changes in fasting glucose and free fatty acid concentrations on indices of β-cell function and glucose metabolism in subjects without diabetes	19
Defective muscle ketone body oxidation disrupts BCAA catabolism by altering mitochondrial branched-chain aminotransferase	19
Heme-based oxygen gasoreceptors	18
Retraction for Jiang et al., volume 304, 2012, p. E74–E86	18
Corrigendum for Cadegiani, volume 318, 2020, p. E-587–E588	17
T-cell factor 7L2 is a novel regulator of osteoblast functions that acts in part by modulation of hypoxia signaling	17
Unraveling adipose tissue proteomic landscapes in severe obesity: insights into metabolic complications and potential biomarkers	17
The promising future of insulin therapy in diabetes mellitus	17
Adipocyte STAT5 (signal transducer and activator of transcription 5) is not required for glucocorticoid-induced metabolic dysfunction	17
Hypothalamus and brainstem circuits in the regulation of glucose homeostasis	17
Exercise training and diet-induced weight loss increase markers of hepatic bile acid (BA) synthesis and reduce serum total BA concentrations in obese women	17
Importance of the route of insulin delivery to its control of glucose metabolism	17
Spatiotemporally quantitative in vivo imaging of mitochondrial fatty acid β-oxidation at cellular-level resolution in mice	16
Obesity protects against sepsis-induced and norepinephrine-induced white adipose tissue browning	16
Increased gut serotonin production in response to bisphenol A structural analogs may contribute to their obesogenic effects	16
Deconstructing interindividual variability in energy metabolism: implications for metabolic health	16
Amelioration of bone fragility by pulsed electromagnetic fields in type 2 diabetic KK-Ay mice involving Wnt/β-catenin signaling	15
Brown adipose tissue metabolism in women is dependent on ovarian status	15
Intestinal retinol saturase is implicated in the development of obesity and epithelial homeostasis upon injury	15
In vitro chronic glycation induces AGEs accumulation reducing insulin-stimulated glucose uptake and increasing GLP1R in adipocytes	14
A new C-peptide minimal model to assess β-cell responsiveness to glucagon in individuals with and without type 2 diabetes	14
A physiologic increase in brain glucagon action alters the hepatic gluconeogenic/glycogenolytic ratio but not glucagon’s overall effect on glucose production	14
Paternal obesity decreases infant MSC mitochondrial functional capacity	14
Female and male C57BL/6J offspring exposed to maternal obesogenic diet develop altered hypothalamic energy metabolism in adulthood	14
Roux-en-Y gastric bypass alleviates kidney inflammation and improves kidney function in db/db mice by activating TLCA/TGR5 pathway	14
Assessment of the incretin effect in healthy subjects: concordance between clamp and OGTT methods	13
Exercise effect on insulin-dependent and insulin-independent glucose utilization in healthy individuals and individuals with type 1 diabetes: a modeling study	13
Circulating insulin-like growth factor system adaptations in hibernating brown bears indicate increased tissue IGF availability	13
Potential role of skeletal muscle glycerophosphocholine in response to altered fluid balance in humans: an in vivo nuclear magnetic resonance study	13
The transcriptional coregulator CITED2 suppresses expression of IRS-2 and impairs insulin signaling in endothelial cells	13
Reply to Lund et al.	13
Sex-specific increases in myostatin and SMAD3 contribute to obesity-related insulin resistance in human skeletal muscle and primary human myotubes	12
Inhibition of the endocannabinoid system reverses obese phenotype in aged mice and partly restores skeletal muscle function	12
Constitutive loss of kynurenine-3-monooxygenase changes circulating kynurenine metabolites without affecting systemic energy metabolism	12
Roles of Circadian Clocks in Macrophage Metabolism: Implications in Inflammation, and Metabolism of Lipids, Glucose, and Amino Acids	12
Absence of Slc39a14/Zip14 in mouse pancreatic beta cells results in hyperinsulinemia	12

Endothelial β1-integrins are necessary for microvascular function and glucose uptake	12
Generation and characterization of a mouse model for one anastomosis gastric bypass surgery	12
Effect of ghrelin on glucose tolerance, gut hormones, appetite, and food intake after sleeve gastrectomy	12
Central lipid sensing pathways contribute to the control of puberty and its alterations in conditions of obesity	12
Key questions and gaps in understanding adipose tissue macrophages and early-life metabolic programming	12
Endoplasmic reticulum stress in pancreatic β cells induces incretin desensitization and β-cell dysfunction via ATF4-mediated PDE4D expression	12
Greater reliance on glycolysis is associated with lower mitochondrial substrate oxidation and insulin sensitivity in infant myogenic MSCs	12
Reduced glucose-stimulated insulin secretion following a 1-wk IGF-1 infusion in late gestation fetal sheep is due to an intrinsic islet defect	12
L-type Calcium Channel Blockade Worsens Glucose Tolerance and β-Cell Function in C57BL6/J Mice Exposed to Intermittent Hypoxia	12
Activation of β-adrenergic receptor signaling prevents glucocorticoid-induced obesity and adipose tissue dysfunction in male mice	11
Pantothenate protects against obesity via brown adipose tissue activation	11
Disruption of hepatic mitochondrial pyruvate and amino acid metabolism impairs gluconeogenesis and endurance exercise capacity in mice	11
Increasing maternal glucose concentrations is insufficient to restore placental glucose transfer in chorionic somatomammotropin RNA interference pregnancies	11
Fasting potentiates insulin-mediated glucose uptake in rested and prior-contracted rat skeletal muscle	11
Ethnic differences in postprandial fatty acid trafficking and utilization between overweight and obese White European and Black African-Caribbean men	11
Effects of follicle-stimulating hormone on energy balance and tissue metabolic health after loss of ovarian function	11
Sedentary time associates detrimentally and physical activity beneficially with metabolic flexibility in adults with metabolic syndrome	11
Central GLP-1 contributes to improved cognitive function and brain glucose uptake after duodenum-jejunum bypass on obese and diabetic rats	10
Extracellular flux analyses reveal differences in mitochondrial PBMC metabolism between high-fit and low-fit females	10
Hepatic mTORC2 compensates for loss of adipose mTORC2 in mediating energy storage and glucose homeostasis	10
An isoproteic cocoa butter-based ketogenic diet fails to improve glucose homeostasis and promote weight loss in obese mice	10
Central androgen action reverses hypothalamic astrogliosis and atherogenic risk factors induced by orchiectomy and high-fat diet feeding in male mice	10
Thermoneutral housing does not accelerate metabolic dysfunction-associated fatty liver disease in male or female C57Bl/6J mice fed a Western diet	10
Obesity wars: may the smell be with you	10
Deletion of complement factor 5 amplifies glucose intolerance in obese male but not female mice	10
Duration of morning hyperinsulinemia determines hepatic glucose uptake and glycogen storage later in the day	10
Brown adipose tissue is not associated with cachexia or increased mortality in a retrospective study of patients with cancer	10
Effect of in utero metformin exposure in gestational diabetes mellitus on infant mesenchymal stem cell metabolism	10
Vitamin E treatment in insulin-deficient diabetic rats reduces cardiac arrhythmias and mortality during severe hypoglycemia	10
PERK/ATF4-dependent expression of the stress response protein REDD1 promotes proinflammatory cytokine expression in the heart of obese mice	10
The influence of interleukin-27 on metabolic fitness in a murine neonatal model of bacterial sepsis	10
Higher AMPK activation in mouse oxidative compared with glycolytic muscle does not correlate with LKB1 or CaMKKβ expression	9
Hepatocyte HIF-2α aggravates NAFLD by inducing ferroptosis through increasing extracellular iron	9
Reproductive and metabolic adaptation to multistressor training in women	9
17α-Estradiol alleviates high-fat diet-induced inflammatory and metabolic dysfunction in skeletal muscle of male and female mice	9
Chronic AT1 blockade improves hyperglycemia by decreasing adipocyte inflammation and decreasing hepatic PCK1 and G6PC1 expression in obese rats	9
Binge alcohol disrupts skeletal muscle core molecular clock independent of glucocorticoids	9
The role of postprandial thermogenesis in the development of impaired glucose tolerance and type II diabetes	9
Fat and not sugar as the determining factor for gut microbiota changes, obesity, and related metabolic disorders in mice	9
Vitamin D and lumisterol novel metabolites can inhibit SARS-CoV-2 replication machinery enzymes	9
Adipose tissue macrophage populations and inflammation are associated with systemic inflammation and insulin resistance in obesity	9
Maternal genetics and diet modulate vitamin A homeostasis of the offspring and affect the susceptibility to obesity in adulthood in mice	9
The enduring metabolic improvement of combining dual amylin and calcitonin receptor agonist and semaglutide treatments in a rat model of obesity and diabetes	9
Understanding how pre- and probiotics affect the gut microbiome and metabolic health	9
Maintenance of thermogenic adipose tissues despite loss of the H3K27 acetyltransferases p300 or CBP	9
The nervous system and adipose tissues: a tale of dialogues	9
Loss of growth hormone signaling in the mouse germline or in adulthood reduces islet mass and alters islet function with notable sex differences	9
Class B1 GPCRs: insights into multireceptor pharmacology for the treatment of metabolic disease	8
The antiemetic actions of GIP receptor agonism	8
17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice	8
Enhanced quantification of α-cell suppression by hyperglycemia using a high-sensitivity glucagon assay	8
Corrigendum for Subramanian et al., volume 326, 2024, p. E182–E205	8
Development of a synbiotic that protects against ovariectomy-induced trabecular bone loss	8
c-Myc overexpression increases ribosome biogenesis and protein synthesis independent of mTORC1 activation in mouse skeletal muscle	8
The effect of repeated hot water immersion on insulin sensitivity, heat shock protein 70, and inflammation in individuals with type 2 diabetes mellitus	8
Effects of 1,144 km of road cycling performed in 7 days: a cardiometabolic imaging study	8
Discovery of a novel regulator, 3β-sulfate-5-cholestenoic acid, of lipid metabolism and inflammation	8
Untargeted metabolomic profiling identifies serum metabolites associated with type 2 diabetes in a cross-sectional study of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study	8
Plasma complement system markers and their association with cardiometabolic risk factors: an ethnic comparison of White European and Black African men	7
Metformin prevents endothelial oxidative stress and microvascular insulin resistance during obesity development in male rats	7
Insulin secretion and action and the response of endogenous glucose production to a lack of glucagon suppression in nondiabetic subjects	7
CYP1A1/1A2 enzymes mediate glucose homeostasis and insulin secretion in mice in a sex-specific manner	7
Hydrolyzed collagen supplementation prior to resistance exercise augments collagen synthesis in a dose-response manner in resistance-trained, middle-aged men	7
The hormonal profile in women using combined monophasic oral contraceptive pills varies across the pill cycle: a temporal analysis of serum endogenous and exogenous hormones using liquid chromatograph	7
Metabolomic signatures of low- and high-adiposity neonates differ based on maternal BMI	7
Influence of innate immune activation on endocrine and metabolic pathways in infancy	7
Advanced glycation end products induce skeletal muscle atrophy and insulin resistance via activating ROS-mediated ER stress PERK/FOXO1 signaling	7
High uric acid induces liver fat accumulation via ROS/JNK/AP-1 signaling	7
The evolution of steatosis and fibrosis in mice on a MASH-inducing diet and the effects of housing temperature	7
Novel effects of the gastrointestinal hormone secretin on cardiac metabolism and renal function	7
Energy expenditure due to gluconeogenesis in pathological conditions of insulin resistance	7
Intramuscular diacylglycerol accumulates with acute hyperinsulinemia in insulin-resistant phenotypes	7
Perineuronal nets’ role in metabolism	7
Circulating interleukin-33 levels in obesity and type 2 diabetes: a systematic review and meta-analysis	7
Human blood contains circulating cell-free mitochondria, but are they really functional?	7
Dual endothelin receptor antagonism increases resting energy expenditure in people with increased adiposity	7
Prostaglandin EP3 receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistance	7
The timing of intermittent hypoxia differentially affects macronutrient intake and energy substrate utilization in mice	7
Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner	7
Disruption of neuromedin B receptor improves mitochondrial oxidative phosphorylation capacity in gastrocnemius muscle of female mice	7

Cold acclimation and pioglitazone combined increase thermogenic capacity of brown and white adipose tissues but this does not translate into higher energy expenditure in mice	7
Menstrual cycle phase differences in myofiber damage and macrophage infiltration following electrical stimulation-induced muscle injury	7
Insulin-induced vasoconstriction is prevalent in muscle microvasculature of otherwise healthy persons with type 1 diabetes	7
Toward a more stable understanding of pregnancy micronutrient metabolism	7
Adipocyte-specific inactivation of NAMPT, a key NAD+ biosynthetic enzyme, causes a metabolically unhealthy lean phenotype in female mice during aging	7