American Journal of Physiology-Endocrinology and Metabolism

Article	Citations
Obesity wars: may the smell be with you	121
The influence of interleukin-27 on metabolic fitness in a murine neonatal model of bacterial sepsis	94
Post-exercise myofibrillar protein synthesis rates do not differ following 1.5 g essential amino acids compared to 15 and 20 g of whey protein in young females	72
Reply to Rodgers: The hepatic glucose-mobilizing effect of glucagon is not mediated by cyclic AMP most of the time	63
Duodenal mucosal resurfacing with a GLP-1 receptor agonist increases postprandial unconjugated bile acids in patients with insulin-dependent type 2 diabetes	58
GIP receptor deletion in mice confers resistance to high-fat diet-induced obesity via alterations in energy expenditure and adipose tissue lipid metabolism	58
A new oral model of free fatty acid kinetics to assess lipolysis in subjects with and without type 2 diabetes	55
Bmal1 promotes prostaglandin E2 synthesis by upregulating Ptgs2 transcription in response to increasing estradiol levels in day 4 pregnant mice	52
Eicosapentaenoic acid changes muscle transcriptome and intervenes in aging-related fiber type transition in male mice	49
Inhibition of GPR120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding	41
Repurposed major urinary protein pheromones and adult sensory neurons: roles in neuron plasticity and experimental diabetes	39
The impact of glucagon to support postabsorptive glucose flux and glycemia in healthy rats and its attenuation in male Zucker diabetic fatty rats	38
Ethnic differences in postprandial fatty acid trafficking and utilization between overweight and obese White European and Black African-Caribbean men	36
A ketogenic diet, regardless of fish oil content, does not affect glucose homeostasis or muscle insulin response in male rats	36
Alterations of urine microRNA-7977/G6PD level in patients with diabetic kidney disease and its association with dysfunction of albumin-induced autophagy in proximal epithelial tubular cells	35
Human liver afferent and efferent nerves revealed by 3-D/Airyscan super-resolution imaging	34
Fasting potentiates insulin-mediated glucose uptake in rested and prior-contracted rat skeletal muscle	33
Brown adipose tissue is not associated with cachexia or increased mortality in a retrospective study of patients with cancer	32
Exercise and estrogen: common pathways in Alzheimer's disease pathology	31
Accelerated developmental adipogenesis programs adipose tissue dysfunction and cardiometabolic risk in offspring born to dams with metabolic dysfunction	30
Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals	30
Retinol-binding protein 4 mRNA translation in hepatocytes is enhanced by activation of mTORC1	29
Higher glucose availability augments the metabolic responses of the C2C12 myotubes to exercise-like electrical pulse stimulation	27
Physical activity and batokines	26
Impact of short-term, pharmacological CARM1 inhibition on skeletal muscle mass, function, and atrophy in mice	25

Skeletal muscle-specific inducible AMPKα1/α2 knockout mice develop muscle weakness, glycogen depletion, and fibrosis that persists during disuse atrophy	25
Transorgan short-chain fatty acid fluxes in the fasted and postprandial state in the pig	25
Skeletal muscle transcriptome response to a bout of endurance exercise in physically active and sedentary older adults	24
Virilizing doses of testosterone decrease circulating insulin levels and differentially regulate insulin signaling in liver and adipose tissue of females	24
Normalization of impaired glucose tolerance after kidney transplantation is associated with improved β-cell function	23
Differential effects of bile acids on the postprandial secretion of gut hormones: a randomized crossover study	22
Identification of newly synthetized proteins by mass spectrometry to understand palmitate-induced early cellular changes in pancreatic islets	21
Pantothenate protects against obesity via brown adipose tissue activation	21
Sedentary time associates detrimentally and physical activity beneficially with metabolic flexibility in adults with metabolic syndrome	21
Comparison of an oral mixed meal plus arginine and intravenous glucose, GLP-1 plus arginine to unmask residual islet function in longstanding type 1 diabetes	20
Arginine-induced glucagon secretion and glucagon-induced enhancement of amino acid catabolism are not influenced by ambient glucose levels in mice	20
Increasing maternal glucose concentrations is insufficient to restore placental glucose transfer in chorionic somatomammotropin RNA interference pregnancies	20
Central GLP-1 contributes to improved cognitive function and brain glucose uptake after duodenum-jejunum bypass on obese and diabetic rats	20
Stimulation of Gs signaling in MC4R cells by DREADD increases energy expenditure, suppresses food intake, and increases locomotor activity in mice	20
Bilirubin as a metabolic hormone: the physiological relevance of low levels	19
Mild stimulatory effect of a probiotic mix on bone mass when treatment is initiated 1.5 weeks after ovariectomy in mice	19
Central androgen action reverses hypothalamic astrogliosis and atherogenic risk factors induced by orchiectomy and high-fat diet feeding in male mice	19
Maternal resistance exercise increases infant energy expenditure	19
Muscle damaging eccentric exercise attenuates disuse-induced declines in daily myofibrillar protein synthesis and transiently prevents muscle atrophy in healthy men	18
Metabolic flux analysis of branched-chain amino and keto acids (BCAA, BCKA) and β-hydroxy β-methylbutyric acid across multiple organs in the pig	18
Effects of exogenous lactate on lipid, protein, and glucose metabolism—a randomized crossover trial in healthy males	18
A reduction of skeletal muscle DHA content does not result in impaired whole body glucose tolerance or skeletal muscle basal insulin signaling in otherwise healthy mice	18
Fight against fibrosis in adipose tissue remodeling	18
Roux-en-Y gastric bypass restores islet function and morphology independent of body weight in ZDF rats	17
Depletion of microglia mitigates cerebrovascular dysfunction in diet-induced obesity mice	17
Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity	17
Mito-Mendelian interactions alter in vivo glucose metabolism and insulin sensitivity in healthy mice	17
A mild and transient form of autosomal recessive pseudohypoaldosteronism type 1 caused by a novel mutation in the SCNN1A gene	17
Cumulative insulin resistance and hyperglycemia with arterial stiffness and carotid IMT progression in 1,779 adolescents: a 9-yr longitudinal cohort study	17
Estimating insulin sensitivity and β-cell function from the oral glucose tolerance test: validation of a new insulin sensitivity and secretion (ISS) model	16
Liver adrenoceptor alpha-1b plays a key role in energy and glucose homeostasis in female mice	16
Exercise training and spexin ameliorate thyroid changes in obese type 2 diabetic rats: the possible interlaying mechanisms	15
Extracellular flux analyses reveal differences in mitochondrial PBMC metabolism between high-fit and low-fit females	15
Effects of circulating endothelial microvesicles isolated from adults with obesity on endothelial cell inflammation, apoptosis, and nitric oxide production	15
Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe disease	15
Long-term light and moderate exercise intervention similarly prevent both hippocampal and glycemic dysfunction in presymptomatic type 2 diabetic rats	15
Renal ischemia/reperfusion induces prominent progressive kidney disease in diabetic mice	15
Sympathetic NPY boosts thermogenic adipocytes	15
Persistent organic pollutants and β-cell toxicity: a comprehensive review	15
Corrigendum for Norgren et al., volume 318, 2020, p. E184–E188	14
Lactylation: novel epigenetic regulatory and therapeutic opportunities	14
Activation of β-adrenergic receptor signaling prevents glucocorticoid-induced obesity and adipose tissue dysfunction in male mice	14
Vitamin D supplementation induces CatG-mediated CD4+ T cell inactivation and restores pancreatic β-cell function in mice with type 1 diabetes	14
Adrenal insufficiency in the COVID-19 era	14
O-linked N-acetylglucosamine modification is essential for physiological adipose expansion induced by high-fat feeding	14
Ketone monoester ingestion increases postexercise serum erythropoietin concentrations in healthy men	14
Characterization of one anastomosis gastric bypass and impact of biliary and common limbs on bile acid and postprandial glucose metabolism in a minipig model	14
Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1	14
Thermoneutral housing does not accelerate metabolic dysfunction-associated fatty liver disease in male or female C57Bl/6J mice fed a Western diet	14
Metabolic consequences of skeletal muscle- and liver-specific BBSome deficiency	13

High-resolution analysis of the cytosolic Ca2+ events in β cell collectives in situ	13
Activation of TFEB protects against diabetic vascular calcification by improving autophagic flux and activating Nrf2 antioxidant system	13
Human skeletal muscle methylome after low-carbohydrate energy-balanced exercise	13
Dichloroacetate as a novel pharmaceutical treatment for cancer-related fatigue in melanoma	13
Corrigendum for Zhang et al., volume 325, 2023, p. E363–E375	13
Delayed and diminished postprandial lactate shuttling in healthy older men and women	12
Celebrating 30 Years of the Discovery of Leptin: A Revolutionary Shift in Understanding Obesity and Metabolism	12
Understanding how pre- and probiotics affect the gut microbiome and metabolic health	12
Metabolomic and transcriptomic remodeling of bone marrow myeloid cells in response to maternal obesity	12
Enhanced ECCD36 signaling promotes skeletal muscle insulin resistance in female mice	12
L-type calcium channel blockade worsens glucose tolerance and β-cell function in C57BL6/J mice exposed to intermittent hypoxia	12
The impact of forearm immobilization and acipimox administration on muscle amino acid metabolism and insulin sensitivity in healthy, young volunteers	11
NADPH oxidase 4-derived hydrogen peroxide counterbalances testosterone-induced endothelial dysfunction and migration	11
Maintenance of thermogenic adipose tissues despite loss of the H3K27 acetyltransferases p300 or CBP	11
Challenges of rapamycin repurposing as a potential therapeutic candidate for COVID-19: implications for skeletal muscle metabolic health in older persons	11
FGF21 contributes to metabolic improvements elicited by combination therapy with exenatide and pioglitazone in patients with type 2 diabetes	11
Kruppel-like factor 14 ameliorated obesity and related metabolic disorders by promoting adipose tissue browning	10
Is nuclear sirtuin SIRT6 a master regulator of immune function?	10
Role of nitration in control of phosphorylase and glycogenolysis in mouse skeletal muscle	10
Slc12a2 loss in insulin-secreting β-cells links development of overweight and metabolic dysregulation to impaired satiation control of feeding	10
Mike Mueckler (1953–2021): the father of the mammalian SLC2 glucose transporter family	10
Tissue-specific responses that constrain glucose oxidation and increase lactate production with the severity of hypoxemia in fetal sheep	10
Whole body lipid oxidation during exercise is impaired with poor insulin sensitivity but not with obesity per se	10
Point: An alternative hypothesis for why exposure to static magnetic and electric fields treats type 2 diabetes	10
Fsp27 plays a crucial role in muscle performance	10
Exercise training induces depot-specific remodeling of protein secretion in skeletal muscle and adipose tissue of obese male mice	10
Ahdc1 is a potent regulator of obesity and energy metabolism	10
Metabolic responses to intermittent hypoxia are regulated by sex and estradiol in mice	9
The enduring metabolic improvement of combining dual amylin and calcitonin receptor agonist and semaglutide treatments in a rat model of obesity and diabetes	9
Diabetic ketoacidosis and COVID-19: what have we learned so far?	9
Exercise-induced benefits on glucose handling in a model of diet-induced obesity are reduced by concurrent nicotinamide mononucleotide	9
Regulation of direct adipose tissue free fatty acid storage during mixed meal ingestion and high free fatty acid concentration conditions	9
The hyperthermic effect of central cholecystokinin is mediated by the cyclooxygenase-2 pathway	9
Deletion of complement factor 5 amplifies glucose intolerance in obese male but not female mice	9
Think (of science) globally, act locally	9
Corrigendum for Zhang et al., volume 318, 2020, p. E625–E635	9
NOD mice have distinct metabolic and immunologic profiles when compared with genetically similar MHC-matched ICR mice	9
Pituitary adenylate cyclase-activating polypeptide receptor activation in the hypothalamus recruits unique signaling pathways involved in energy homeostasis	9
Both moderate- and high-intensity exercise training increase intramyocellular lipid droplet abundance and modify myocellular distribution in adults with obesity	9
Short-term physical inactivity induces diacylglycerol accumulation and insulin resistance in muscle via lipin1 activation	9
1,25-Dihydroxyvitamin D deficiency accelerates male reproductive senescence in aging mice and 1,25(OH)2D3alleviates oxidative stress via NF-κB/SOD	9
Divergent serum metabolomic, skeletal muscle signaling, transcriptomic, and performance adaptations to fasted versus whey protein-fed sprint interval training	9
The role of preproglucagon peptides in regulating β-cell morphology and responses to streptozotocin-induced diabetes	8
Binge alcohol disrupts skeletal muscle core molecular clock independent of glucocorticoids	8
Recovery from FOLFOX chemotherapy-induced systemic and skeletal muscle metabolic dysfunction in mice	8
Adaptive responses in uteroplacental metabolism and fetoplacental nutrient shuttling and sensing during placental insufficiency	8
Independent of mitochondrial respiratory function, dietary nitrate attenuates HFD-induced lipid accumulation and mitochondrial ROS emission within the liver	8
RORα contributes to the maintenance of genome ploidy in the liver of mice with diet-induced nonalcoholic steatohepatitis	8
Higher protein intake during resistance training does not potentiate strength, but modulates gut microbiota, in middle-aged adults: a randomized control trial	8
Leptin receptor-expressing cells in the ventromedial nucleus of the hypothalamus contribute to enhanced CCK-induced satiety following central leptin injection	8
“Turning up the heat”: role of neurotrophic batokines in the postnatal maturation and remodeling of brown adipose tissue in deer mice	8
Phosphorylation of AS160-serine 704 is not essential for exercise-increase in insulin-stimulated glucose uptake by skeletal muscles from female or male rats	8
Six-day dry immersion leads to downregulation of slow-fiber type and mitochondria-related genes expression	8
Carbohydrate intake in recovery from aerobic exercise differentiates skeletal muscle microRNA expression	8
Chronic pancreatitis-associated metabolic bone diseases: epidemiology, mechanisms, and clinical advances	8
Thermogenic recruitment of brown and brite/beige adipose tissues is not obligatorily associated with macrophage accretion or attrition	8
A modest change in housing temperature alters whole body energy expenditure and adipocyte thermogenic capacity in mice	7
The role of postprandial thermogenesis in the development of impaired glucose tolerance and type II diabetes	7
The effect of acute and 14-day exogenous ketone supplementation on glycemic control in adults with type 2 diabetes: two randomized controlled trials	7
Acute binge alcohol alters whole body metabolism and the time-dependent expression of skeletal muscle-specific metabolic markers for multiple days in mice	7
DNMT1-mediated lncRNA MEG3 methylation accelerates endothelial-mesenchymal transition in diabetic retinopathy through the PI3K/Akt/mTOR signaling pathway	7
Impaired postprandial adipose tissue microvascular blood flow responses to a mixed-nutrient meal in first-degree relatives of adults with type 2 diabetes	7
Evaluating glucose-dependent insulinotropic polypeptide and glucagon as key regulators of insulin secretion in the pancreatic islet	7
An isoproteic cocoa butter-based ketogenic diet fails to improve glucose homeostasis and promote weight loss in obese mice	7
Prematurity blunts the insulin- and amino acid-induced stimulation of translation initiation and protein synthesis in skeletal muscle of neonatal pigs	7
Glucose-dependent activation, activity, and deactivation of beta cell networks in acute mouse pancreas tissue slices	7
Three weeks of interrupting sitting lowers fasting glucose and glycemic variability, but not glucose tolerance, in free-living women and men with obesity	7
Hepatic mTORC2 compensates for loss of adipose mTORC2 in mediating energy storage and glucose homeostasis	7
Hepatocyte HIF-2α aggravates NAFLD by inducing ferroptosis through increasing extracellular iron	7
Inhibition of protein kinase C-α and activation of ezrin by Lactobacillus acidophilus restore Na+/H+ exchange activity and fluid absorption in db/db mice	7
More than meets the islet: aligning nutrient and paracrine inputs with hormone secretion in health and disease	7
Meal sugar-protein balance determines postprandial FGF21 response in humans	7
Evaluation of safety and effectiveness of NAD in different clinical conditions: a systematic review	7
17α-Estradiol alleviates high-fat diet-induced inflammatory and metabolic dysfunction in skeletal muscle of male and female mice	7
Bee bread mitigates downregulation of steroidogenic genes, decreased spermatogenesis, and epididymal oxidative stress in male rats fed with high-fat diet	7
CB1Rs in VMH neurons regulate glucose homeostasis but not body weight	7
IGF-1 LR3 does not promote growth in late-gestation growth-restricted fetal sheep	7
Metabolic labeling unveils alterations in the turnover of HDL-associated proteins during diabetes progression in mice	7
Hunger Games: A Role for cAMP	7
Brain region-specific disruption of mitochondrial bioenergetics in cynomolgus macaques fed a Western versus a Mediterranean diet	7

Species differences of fatty liver diseases: comparisons between human and feline	7
Acute carbohydrate overfeeding: a redox model of insulin action and its impact on metabolic dysfunction in humans	7
The nervous system and adipose tissues: a tale of dialogues	7