American Journal of Chinese Medicine

Papers
(The median citation count of American Journal of Chinese Medicine is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Chinese Materia Medica in Treating Depression: The Role of Intestinal Microenvironment71
Ginsenoside Rg6 Improves Cisplatin Resistance in Epithelial Ovarian Cancer Cells via Suppressing Fucosylation and Inducing Autophagy66
Solasonine Inhibits Cancer Stemness and Metastasis by Modulating Glucose Metabolism via Wnt/β-Catenin/Snail Pathway in Osteosarcoma55
Umbelliferone Inhibits Migration, Invasion and Inflammation of Rheumatoid Arthritis Fibroblast-Like Synoviocytes and Relieves Adjuvant-Induced Arthritis in Rats by Blockade of Wnt/β-Catenin Signaling 50
Neuroprotective Effects of Paeonia lactiflora Through the Regulation of Gut Dubosiella in an MPTP-Induced Parkinson’s Disease Mouse Model48
Chinese Medicine-Derived Salvianolic Acid B for Disease Therapy: A Scientometric Study46
Astragalus membranaceus as a Drug Candidate for Inflammatory Bowel Disease: The Preclinical Evidence44
Research Progress of Chinese Medicine in Treating Chronic Liver Disease by Regulating Autophagy40
Mechanism of Acupuncture in Treating Obesity: Advances and Prospects37
Effects of Crocin on CCL2/CCR2 Inflammatory Pathway in Monocrotaline-Induced Pulmonary Arterial Hypertension Rats36
Cornel Iridoid Glycoside and Its Effective Component Regulate ATPase Vps4A/JNK to Alleviate Autophagy Deficit with Autophagosome Accumulation33
Deer Velvet Antler Extracts Exert Anti-Inflammatory and Anti-Arthritic Effects on Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes and Distinct Mouse Arthritis30
Curcumin-Pretreated Adipose-Derived Stem Cells Enhance the Neuroprotective Ability to Repair Rheumatoid Arthritis-Induced Damage in the Rat Brain28
Regulating the Imbalance of Gut Microbiota by Smilax china L. Polyphenols to Alleviate Dextran Sulfate Sodium-induced Inflammatory Bowel Diseases26
Ginsenoside Rb1 Relieves Cellular Senescence and Pulmonary Fibrosis by Promoting NRF2/QKI/SMAD7 Axis25
Nrf2-Dependent Protective Effect of Paeoniflorin on α-Naphthalene Isothiocyanate-Induced Hepatic Injury25
Arteannuin B Enhances the Effectiveness of Cisplatin in Non-Small Cell Lung Cancer by Regulating Connexin 43 and MAPK Pathway25
Probiotic Fermentation of Herbal Medicine: Progress, Challenges, and Opportunities24
Formononetin Alleviates Ischemic Acute Kidney Injury by Regulating Macrophage Polarization through KLF6/STAT3 Pathway23
Multidirectional Intervention of Chinese Herbal Medicine in the Prevention and Treatment of Atherosclerosis: From Endothelial Protection to Immunomodulation22
20(S)-Protopanaxadiol fromPanax ginsengInduces Apoptosis and Autophagy in Gastric Cancer Cells by Inhibiting Src22
Mangiferin Protects against Angiotensin-II-Enhanced Hypertrophic Markers and Apoptosis in H9c2 Cardiomyocytes22
Efficacy of Oriental Exercises for Non-Motor Symptoms and Quality of Life in Parkinson’s Disease: A Systematic Review and Meta-Analysis21
Chinese Medicine for the Treatment of Liver Cirrhosis: The Mechanism of Cellular Autophagy21
Liquiritigenin, an Active Ingredient of Liquorice, Alleviates Acute Kidney Injury by VKORC1-Mediated Ferroptosis Inhibition21
Gut Flora Mediates the Rapid Tolerance of Electroacupuncture on Ischemic Stroke by Activating Melatonin Receptor through Regulating Indole-3-Propionic Acid20
Catalpol from Rehmannia glutinosa Targets Nrf2/NF-κB Signaling Pathway to Improve Renal Anemia and Fibrosis20
Traditional Chinese Medicine in Osteoporosis Intervention and the Related Regulatory Mechanism of Gut Microbiome20
The Role of Traditional Chinese Medicine in Cancer Immunotherapy: Current Status and Future Directions20
Ginsenoside Rd Attenuates Myocardial Ischemia/Reperfusion Injury by Inhibiting Inflammation and Apoptosis through PI3K/Akt Signaling Pathway19
Traditional Chinese Patent Medicine in the Treatment of Alzheimer’s Disease: A Systematic Review and Network Meta-Analysis19
Cinnamon for Metabolic Diseases and Their Cardiovascular and Hepatic Complications: A Mechanistic Review19
Individualized Diagnosis and Prescription in Traditional Medicine: Decision-Making Process Analysis and Machine Learning-Based Analysis Tool Development19
Amygdalin Induced Mitochondria-Mediated Apoptosis of Lung Cancer Cells via Regulating NFκB-1/NFκB Signaling Cascadein Vitroandin Vivo18
Xanthohumol Promotes Skp2 Ubiquitination Leading to the Inhibition of Glycolysis and Tumorigenesis in Ovarian Cancer18
Mechanisms of Dihydromyricetin for Improving Hepatic Fibrosis through the Integration of Metabolomics and Gut Microbiota17
Research Progress on the Antitumor Molecular Mechanism of Ginsenoside Rh217
Perioperative Acupuncture Optimizes Surgical Outcomes: Theory, Clinical Practice and Future Perspectives16
The Changing Global Landscape in the Development of Artemisinin-Based Treatments: A Clinical Trial Perspective16
Salvianolic Acid Ameliorates Pressure Overload-Induced Cardiac Endothelial Dysfunction via Activating HIF1α/HSF1/CD31 Pathway16
Research Progress of Immunomodulation on Anti-COVID-19 and the Effective Components from Traditional Chinese Medicine16
Andrographolide Inhibits Lipotoxicity-Induced Activation of the NLRP3 Inflammasome in Bone Marrow-Derived Macrophages15
Research Progress of Traditional Chinese Medicine Monomers in Reversing Multidrug Resistance of Breast Cancer15
Coptis chinensis-Induced Changes in Metabolomics and Gut Microbiota in Rats15
Qigong and Tai Chi on Human Health: An Overview of Systematic Reviews15
Prenylated Flavonoids in Sophora flavescens: A Systematic Review of Their Phytochemistry and Pharmacology15
IL-10-dependent Effect of Chinese Medicine Abelmoschus manihot on Alleviating Intestinal Inflammation and Modulating Gut Microbiota15
Ginsenoside Rh2 Regulates the CFAP20DC-AS1/MicroRNA-3614-3p/BBX and TNFAIP3 Axis to Induce Apoptosis in Breast Cancer Cells15
New Perspectives on Chinese Medicine in Treating Hepatic Fibrosis: Lipid Droplets in Hepatic Stellate Cells15
A Clinical Study on the Relationship Among Insomnia, Tongue Diagnosis, and Oral Microbiome14
Protective Effects and Therapeutics of Ginsenosides for Improving Endothelial Dysfunction: From Therapeutic Potentials, Pharmaceutical Developments to Clinical Trials14
Targeting Ferroptosis in Cancer by Natural Products: An Updated Review14
ERRATUM — The Effects of Patchouli Alcohol on Diarrhea-Predominant Irritable Bowel Syndrome are Correlated with Phenotypic Plasticity in Myenteric Neurons and the Targeted Regulation of Myosin Va14
Smilax china Polyphenols Stimulate Browning via β3-Adrenergic Receptor/AMP-Activated Protein Kinase α Signaling Pathway in 3T3-L1 Adipocytes14
Ruscogenin Alleviates Myocardial Ischemia via Myosin IIA-Dependent Mitochondrial Fusion and Fission Balance14
The Pharmacological Rationales and Molecular Mechanisms ofGanoderma lucidumPolysaccharides for the Therapeutic Applications of Multiple Diseases14
Efficacy and Mechanisms of Natural Products as Therapeutic Interventions for Chronic Respiratory Diseases13
Astragaloside IV Alleviates Doxorubicin-Induced Cardiotoxicity by Inhibiting Cardiomyocyte Pyroptosis through the SIRT1/NLRP3 Pathway13
Therapeutic Potential of Traditional Chinese Medicine Against Osteoarthritis: Targeting the Wnt Signaling Pathway13
Pharmacological Effects of a Ginseng-Containing Chinese Medicine Formula in Treating Hepatocellular Carcinoma Based on Comprehensive Bioinformatics and Experimental Validation13
Curcumin Analog L48H37 Induces Apoptosis in Human Oral Cancer Cells by Activating Caspase Cascades and Downregulating the Inhibitor of Apoptosis Proteins through JNK/p38 Signaling13
Advances in the Application of Traditional Chinese Medicine Using Artificial Intelligence: A Review13
Ginsenoside Rg5 Improves Sleep by Regulating Energy Metabolism in Sleep-Deprived Rats13
Anticancer Effects of Morusin in Prostate Cancer via Inhibition of Akt/mTOR Signaling Pathway13
Cardioprotective Effects of Tetrahydropalmatine on Acute Myocardial Infarction in Rats13
Triterpenoid Compounds from Cyclocarya paliurus: A Review of Their Phytochemistry, Quality Control, Pharmacology, and Structure–Activity Relationship12
Target-Specific Drug Discovery of Natural Products against SARS-CoV-2 Life Cycle and Cytokine Storm in COVID-1912
Therapeutic Effects ofAlisma orientaleand its Active Constituents on Cardiovascular Disease and Obesity12
Acupuncture: A Review of the Safety and Adverse Events and the Strategy of Potential Risk Prevention12
Research Progress of Chinese Medicine in the Regulation of Liver Fibrosis-Related Signaling Pathways12
Saponins From Platycodon grandiflorum Reduces Cisplatin-Induced Intestinal Toxicity in Mice through Endoplasmic Reticulum Stress-Activated Apoptosis12
Mechanistic Role ofScutellaria baicalensisGeorgi in Breast Cancer Therapy12
Traditional Chinese Medicine Formulae and Chinese Patent Medicines for the Treatment of Diabetic Kidney Disease: Efficacies and Mechanisms12
Advances in Anti-Osteoporosis Polysaccharides Derived from Medicinal Herbs and Other Edible Substances12
Astragaloside I from Astragalus Attenuates Diabetic Kidney Disease by Regulating HDAC3/Klotho/TGF-β1 Loop12
Ginsenoside Rk1 Ameliorates ER Stress-Induced Apoptosis through Directly Activating IGF-1R in Mouse Pancreatic β-Cells and Diabetic Pancreas12
The Role ofGynostemma pentaphyllumin Regulating Hyperlipidemia12
Veratramine Inhibits the Cell Cycle Progression, Migration, and Invasion via ATM/ATR Pathway in Androgen-Independent Prostate Cancer11
Chicoric Acid Presented NLRP3-Mediated Pyroptosis through Mitochondrial Damage by PDPK1 Ubiquitination in an Acute Lung Injury Model11
Notoginsenoside R1, An Active Compound from Panax notoginseng, Inhibits Hepatic Stellate Cell Activation and Liver Fibrosis via MAPK Signaling Pathway11
Salidroside Ameliorates Ischemia-Induced Neuronal Injury through AMPK Dependent and Independent Pathways to Maintain Mitochondrial Quality Control11
Neferine Suppresses Experimental Colitis-Associated Colorectal Cancer by Inhibition of NF-κB p65 and STAT311
Zingiber officinale: A Systematic Review of Botany, Phytochemistry and Pharmacology of Gut Microbiota-Related Gastrointestinal Benefits11
Baicalin Blocks Colon Cancer Cell Cycle and Inhibits Cell Proliferation through miR-139-3p Upregulation by Targeting CDK1611
Isoliquiritigenin Inhibits Oral Squamous Cell Carcinoma and Overcomes Chemoresistance by Destruction of Survivin11
Taraxacum: A Review of Ethnopharmacology, Phytochemistry and Pharmacological Activity11
Panax notoginseng Saponins Activate Nuclear Factor Erythroid 2-Related Factor 2 to Inhibit Ferroptosis and Attenuate Inflammatory Injury in Cerebral Ischemia–Reperfusion11
Bergenin Inhibits Tumor Growth and Overcomes Radioresistance by Targeting Aerobic Glycolysis11
Therapeutic Potentials of Medicinal Leech in Chinese Medicine11
Effects of Chinese Medicine on Pyroptosis in Coronary Heart Disease11
Botany, Traditional Use, Phytochemistry, Pharmacology and Clinical Applications of Rhubarb (Rhei Radix et Rhizome): A Systematic Review11
Astragaloside IV Ameliorates Colonic Adenomatous Polyps Development by Orchestrating Gut Bifidobacterium and Serum Metabolome10
Chlorogenic Acid Ameliorates Acetaminophen-Induced Liver Injury Through AMPK/mTOR/ULK1-Mediated Autophagy Activation10
The Phytochemistry of Ganoderma Species and their Medicinal Potentials10
Traditional Chinese Medicine: A Promising Treatment Option for Intestinal Fibrosis10
Pharmacokinetics and Biological Activities of Notoginsenoside R1: A Systematical Review10
Glycyrrhizin and the Related Preparations: An Inspiring Resource for the Treatment of Liver Diseases10
Curcumol Reduces Aerobic Glycolysis and Overcomes Chemoresistance by Inducing Cdh1-Mediated Skp2 Ubiquitination10
Gardenia jasminoidesExtract GJ-4 Alleviates Memory Deficiency of Vascular Dementia in Rats through PERK-Mediated Endoplasmic Reticulum Stress Pathway10
Traditional Chinese Herbal Medicine for Allergic Diseases: A Review10
Effect and Mechanism of Qingfei Paidu Decoction in the Management of Pulmonary Fibrosis and COVID-1910
Falcarindiol Stimulates Apoptotic and Autophagic Cell Death to Attenuate Cell Proliferation, Cell Division, and Metastasis through the PI3K/AKT/mTOR/p70S6K Pathway in Human Oral Squamous Cell Carcinom10
Lupeol Alleviates Myocardial Ischemia-Reperfusion Injury in Rats by Regulating NF-κB and Nrf2 Pathways9
Osthole, a Coumarin from Cnidium monnieri: A Review on Its Pharmacology, Pharmacokinetics, Safety, and Innovative Drug Delivery Platforms9
Bufalin Inhibits Tumorigenesis and SREBP-1-Mediated Lipogenesis in Hepatocellular Carcinoma via Modulating the ATP1A1/CA2 Axis9
Proapoptotic Effect of Icariin on Human Ovarian Cancer Cells via the NF-κB/PI3K-AKT Signaling Pathway: A Network Pharmacology-Directed Experimental Investigation9
Ginsenoside Rg5: A Review of Anticancer and Neuroprotection with Network Pharmacology Approach9
Mechanisms of Danggui Buxue Tang on Hematopoiesis via Multiple Targets and Multiple Components: Metabonomics Combined with Database Mining Technology9
Traditional Chinese Medicine for Cancer Treatment9
Therapeutic Targets and Natural Product Screening for Cognitive Impairments Associated with Ferroptosis in Wilson’s Disease9
Ferroptosis in Endometriosis: Traditional Chinese Medicine Interventions and Mechanistic Insights9
Red Yeast Rice and Statin Therapy in Patients with Hypercholesterolemia and the Comorbidities: A Retrospective Cohort Study on Lipid-Lowering Effects and Cardiovascular Outcomes9
Calycosin Enhances Heat Shock Related-Proteins in H9c2 Cells to Modulate Survival and Apoptosis against Heat Shock9
The Effectiveness of Acupuncture for Low Back Pain: An Umbrella Review and Meta-Analysis9
The Pharmacology and Toxicology of Ginkgolic Acids: Secondary Metabolites from Ginkgo biloba9
Amelioration of Lung Fibrosis by Total Flavonoids of Astragalus via Inflammatory Modulation and Epithelium Regeneration9
Targeting Autophagy with Geniposide Ameliorates Atherosclerosis in ApoE−∕− Mice9
Effects of Curcuminoids and Surfactant-Formulated Curcumin on Chemo-Resistant Colorectal Cancer9
Trends and Characteristics of the Whole-Grain Diet9
Schisanhenol Attenuates OxLDL-Induced Endothelial Dysfunction via an AMPK-Dependent Mechanism9
Astragalus membranaceus Polysaccharide Regulates Small Intestinal Microbes and Activates IL-22 Signal Pathway to Promote Intestinal Stem Cell Regeneration in Aging Mice9
Rutaecarpine Alleviates Early Brain Injury-Induced Inflammatory Response Following Subarachnoid Hemorrhage via SIRT6/NF-κB Pathway9
Research Progress in Ulcerative Colitis: The Role of Traditional Chinese Medicine on Gut Microbiota and Signaling Pathways9
Curcumin Inhibits T Follicular Helper Cell Differentiation in Mice with Dextran Sulfate Sodium (DSS)-Induced Colitis8
Traditional Chinese Medicine for COVID-19: A Network Meta-Analysis and Systematic Review8
The Effectiveness of Traditional Chinese Medicine in Treating Malignancies via Regulatory Cell Death Pathways and the Tumor Immune Microenvironment: A Review of Recent Advances8
Gambogic Acid Induces HO-1 Expression and Cell Apoptosis through p38 Signaling in Oral Squamous Cell Carcinoma8
Role of Traditional Chinese Medicine in Lung Cancer Management: A Review8
Efficacy and Safety of Chinese Medicine for COVID-19: A Systematic Review and Meta-Analysis8
A Review of Traditional Chinese Medicine for Triple Negative Breast Cancer and the Pharmacological Mechanisms8
Ginsenoside Re Attenuates Cisplatin-Induced Intestinal Toxicity via Suppressing GSK-3β-Dependent Wnt/β-Catenin Signaling Pathway In Vivo and In Vitro7
A Novel Paradigm Defines Functional Molecule Clusters for an Anti-Alzheimer’s Disease Recipe from Traditional Chinese Medicine7
Effects of Resveratrol on Pulmonary Fibrosis via TGF-β/Smad/ERK Signaling Pathway7
The Effects of Patchouli Alcohol on Diarrhea-Predominant Irritable Bowel Syndrome are Correlated with Phenotypic Plasticity in Myenteric Neurons and the Targeted Regulation of Myosin Va7
Dietary Supplements for Pain Relief in Patients with Fibromyalgia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials7
Gut Microbiota Regulation by Acupuncture and Moxibustion: A Systematic Review and Meta-Analysis7
Berberine Metabolites Stimulate GLP-1 Secretion by Alleviating Oxidative Stress and Mitochondrial Dysfunction7
Identifying Dose Components of Manual Acupuncture to Determine the Dose–Response Relationship of Acupuncture Treatment: A Systematic Review7
Renoprotective Effect of Isoorientin in Diabetic Nephropathy via Activating Autophagy and Inhibiting the PI3K-AKT-TSC2-mTOR Pathway7
Integrative Analysis of the Gut Microbiota and Metabolome in Obese Mice with Electroacupuncture by 16S rRNA Gene Sequencing and HPLC–MS-based Metabolic Profiling7
The Role of Traditional Chinese Medicine in the Management of Cervical Cancer7
Pharmacological Benefits and Underlying Mechanisms of Salvia miltiorrhiza against Molecular Pathology of Various Liver Diseases: A Review7
Ginkgo biloba and Its Chemical Components in the Management of Alzheimer’s Disease7
Efficacy and Safety of Glycyrrhizic Acid in Treatment of Autoimmune Hepatitis6
Total Flavonoids of Astragalus Inhibit Activated CD4+ T Cells and Regulate Differentiation of Th17/Th1/Treg Cells in Experimental Autoimmune Encephalomyelitis Mice by JAK/STAT and NFκB Signaling Pathw6
Nanotechnology-Based Drug Delivery System for Anticancer Active Ingredients from Traditional Chinese Medicines: A Review6
The Pharmacological Effects of Gastrodin and the Progress in the Treatment of Neurological Disorders6
A Review of Traditional Chinese Medicine on Treatment of Diabetic Nephropathy and the Involved Mechanisms6
Traditional Chinese Medicine for Alzheimer’s Disease: A Systematic Review and Meta-Analysis6
Tanshinone IIA Microemulsion Protects against Cerebral Ischemia Reperfusion Injury via Regulating H3K18ac and H4K8acIn VivoandIn Vitro6
Astragalus Total Saponins Ameliorate Peritoneal Fibrosis by Promoting Mitochondrial Synthesis and Inhibiting Apoptosis6
Tanshinone IIA: New Perspective on the Anti-Tumor Mechanism of A Traditional Natural Medicine6
Neuroprotective Effects ofAlpinia oxyphyllaMiq against Mitochondria-Related Apoptosis by the Interactions between Upregulated p38 MAPK Signaling and Downregulated JNK Signaling in the Subacute 6
Apigenin Suppresses Innate Immune Responses and Ameliorates Lipopolysaccharide-Induced Inflammation via Inhibition of STING/IRF3 Pathway6
In SilicoPrediction of Andrographolide Dosage Regimens for COVID-19 Treatment6
The Role of Traditional Chinese Medicines in the Treatment of Osteoporosis6
Anti-Inflammatory and Anti-oxidative Effects of Puerarin in Postmenopausal Cardioprotection: Roles of Akt and Heme Oxygenase-16
A Comprehensive Review of Licorice: The Preparation, Chemical Composition, Bioactivities and Its Applications6
Efficacy and Safety of Shengmai Preparation Combined with Western Medicine for Coronary Heart Disease: A Systematic Review and Meta-Analysis6
Therapeutic Effects of Natural Products in the Treatment of Chronic Diseases: The Role in Regulating KEAP1–NRF2 Pathway5
Korean Red Ginseng Marc-Derived Gintonin Improves Alzheimer’s Cognitive Dysfunction by Upregulating LPAR15
Acupuncture and Moxibustion for Inflammatory Bowel Disease: Regulatory Mechanisms Revealed by Microbiome and Metabolomic Analysis5
Acupuncture for Fibromyalgia: A Review Based on Multidimensional Evidence5
Effectiveness of Chinese Herbal Medicine in Patients with COVID-19 During the Omicron Wave in Hong Kong: A Retrospective Case-Controlled Study5
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-κB Pathways5
Sophora alopecuroides Alleviates Neuroinflammation and Oxidative Damage of Parkinson’s Disease In Vitro and In Vivo5
Integrated Metabonomic Study on the Relationship between Medicinal Properties and Efficacy ofRehmanniae Radix5
Study on the Chemical Constituents, Pharmacological Activities, and Clinical Application of Taxus5
Chinese Herbal Medicine, Alternative or Complementary, for Endometriosis-Associated Pain: A Meta-Analysis5
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