American Journal of Chinese Medicine

Article	Citations
Mast Cells in Acupoint Sensitization: Mechanisms and Research Advances	136
Chinese Materia Medica in Treating Depression: The Role of Intestinal Microenvironment	66
Astragalus membranaceus as a Drug Candidate for Inflammatory Bowel Disease: The Preclinical Evidence	65
Ginsenoside Rg6 Improves Cisplatin Resistance in Epithelial Ovarian Cancer Cells via Suppressing Fucosylation and Inducing Autophagy	63
Tanshinone IIA Alleviates Pyroptosis through SIRT1/NLRP3 Pathway to Improve Diabetic Nephropathy	55
Solasonine Inhibits Cancer Stemness and Metastasis by Modulating Glucose Metabolism via Wnt/β-Catenin/Snail Pathway in Osteosarcoma	47
Chinese Medicine-Derived Salvianolic Acid B for Disease Therapy: A Scientometric Study	47
Neuroprotective Effects of Paeonia lactiflora Through the Regulation of Gut Dubosiella in an MPTP-Induced Parkinson’s Disease Mouse Model	44
Corrigendum — Gardenia jasminoides Extract GJ-4 Aleviates Memory Defciency of Vascular Dementia in Rats through PERK-Mediated Endoplasmic Reticulum Stress Pathway	43
Advancing Traditional Chinese Medicine Research through Network Pharmacology: Strategies for Target Identification, Mechanism Elucidation and Innovative Therapeutic Applications	42
Mechanism of Acupuncture in Treating Obesity: Advances and Prospects	41
Research Progress of Chinese Medicine in Treating Chronic Liver Disease by Regulating Autophagy	39
Ginsenoside Rb1 Relieves Cellular Senescence and Pulmonary Fibrosis by Promoting NRF2/QKI/SMAD7 Axis	36
Personalized Traditional Chinese Medicine in Oncology: Bridging the Macro State with Micro Targets	34
Gambogic Acid, a Caged Xanthone: Therapeutic Effects, Pharmacokinetics, Toxicological Properties, and Delivery Platforms	34
Formononetin Alleviates Ischemic Acute Kidney Injury by Regulating Macrophage Polarization through KLF6/STAT3 Pathway	33
20(S)-Protopanaxadiol fromPanax ginsengInduces Apoptosis and Autophagy in Gastric Cancer Cells by Inhibiting Src	32
The Role of Traditional Chinese Medicine in Targeting NF-κB Ubiquitination Against Ischemic Stroke	28
Probiotic Fermentation of Herbal Medicine: Progress, Challenges, and Opportunities	27
Silybin for Liver Diseases via Anti-Oxidative Stress: A Comprehensive Review	27
The Role of Artesunate in Cancer Management: Mechanisms of Biomedical Effects and Toxicology	27
Mangiferin Protects against Angiotensin-II-Enhanced Hypertrophic Markers and Apoptosis in H9c2 Cardiomyocytes	25
Multidirectional Intervention of Chinese Herbal Medicine in the Prevention and Treatment of Atherosclerosis: From Endothelial Protection to Immunomodulation	25
Chinese Medicine for the Treatment of Liver Cirrhosis: The Mechanism of Cellular Autophagy	25
Research Progress on Traditional Uses, Chemical Composition, Pharmacological Actions, and Clinical Applications of Ginseng-Containing Sijunzi Decoction	25

Traditional Chinese Patent Medicine in the Treatment of Alzheimer’s Disease: A Systematic Review and Network Meta-Analysis	24
Cinnamon for Metabolic Diseases and Their Cardiovascular and Hepatic Complications: A Mechanistic Review	24
Ginsenoside Rd Attenuates Myocardial Ischemia/Reperfusion Injury by Inhibiting Inflammation and Apoptosis through PI3K/Akt Signaling Pathway	24
Ethnomedicine, Botany, Phytochemistry, Pharmacology, Pharmacokinetics, and Toxicity of Rhizoma Corydalis: A Systematic Review	23
Efficacy of Oriental Exercises for Non-Motor Symptoms and Quality of Life in Parkinson’s Disease: A Systematic Review and Meta-Analysis	23
Nobiletin Ameliorated the Development of Diabetic Kidney Disease via Modulating Ferroptosis and Epithelial–Mesenchymal Transition Involving Gut–Kidney Axis	22
Catalpol from Rehmannia glutinosa Targets Nrf2/NF-κB Signaling Pathway to Improve Renal Anemia and Fibrosis	22
Traditional Chinese Medicine in Osteoporosis Intervention and the Related Regulatory Mechanism of Gut Microbiome	21
Liquiritigenin, an Active Ingredient of Liquorice, Alleviates Acute Kidney Injury by VKORC1-Mediated Ferroptosis Inhibition	21
The Role of Traditional Chinese Medicine in Cancer Immunotherapy: Current Status and Future Directions	21
Astragaloside IV Improves Pulmonary Vascular Endothelial Dysfunction in Pulmonary Arterial Hypertension by Inhibiting Ferroptosis through Modulation of the Calpain-1/TGF-β/TFRC Pathway	21
Polygonati Rhizoma: Geographic Distribution, Traditional Use, Component Transformation, Pharmacological Activity, and Clinical Application	20
Xanthohumol Promotes Skp2 Ubiquitination Leading to the Inhibition of Glycolysis and Tumorigenesis in Ovarian Cancer	20
Celastrol Alleviates Intestinal Epithelial Permeability by Inhibiting Ferroptosis through PI3K/Akt/FOXO1/HO-1 Signaling Pathway	20
Targeting Myeloperoxidase in Disease Pathogenesis: Emerging Roles of Natural Products in Therapeutic Modulation	20
Research Progress on the Antitumor Molecular Mechanism of Ginsenoside Rh2	18
NOTICE OF RETRACTION: Therapeutic Prospects of Ursolic Acid in Colorectal Cancer: Modulation of the Wnt/β-Catenin Signaling Pathway and Gut Microbiota Composition	18
Quercetin Ameliorates Learning and Memory in OVX/D-gal-Induced Alzheimer’s Disease in Rats by Inhibiting Neuroinflammation via cGAS-STING Signal Pathway	18
Mechanisms of Dihydromyricetin for Improving Hepatic Fibrosis through the Integration of Metabolomics and Gut Microbiota	18
Research Progress of Immunomodulation on Anti-COVID-19 and the Effective Components from Traditional Chinese Medicine	18
Targeting Ferroptosis in Cancer by Natural Products: An Updated Review	18
Poria cocos Polysaccharides Attenuate Cardiac Injury by Inhibiting CaMKII-Mediated P38/NF-κB/NLRP3 Signaling Pathway to Reduce Sepsis-Induced Apoptosis and Inflammation	18
Andrographolide Inhibits Lipotoxicity-Induced Activation of the NLRP3 Inflammasome in Bone Marrow-Derived Macrophages	18
Coptis chinensis-Induced Changes in Metabolomics and Gut Microbiota in Rats	18
Research Progress of Traditional Chinese Medicine Monomers in Reversing Multidrug Resistance of Breast Cancer	17
Cistanche deserticola Polysaccharides Mitigate Alzheimer’s Disease Progression by Dynamic Regulation of Gut Microbiota Composition and Metabolites	17
ERRATUM — The Effects of Patchouli Alcohol on Diarrhea-Predominant Irritable Bowel Syndrome are Correlated with Phenotypic Plasticity in Myenteric Neurons and the Targeted Regulation of Myosin Va	17
IL-10-dependent Effect of Chinese Medicine Abelmoschus manihot on Alleviating Intestinal Inflammation and Modulating Gut Microbiota	17
New Perspectives on Chinese Medicine in Treating Hepatic Fibrosis: Lipid Droplets in Hepatic Stellate Cells	17
Prenylated Flavonoids in Sophora flavescens: A Systematic Review of Their Phytochemistry and Pharmacology	17
Ruscogenin Alleviates Myocardial Ischemia via Myosin IIA-Dependent Mitochondrial Fusion and Fission Balance	16
Efficacy and Mechanisms of Natural Products as Therapeutic Interventions for Chronic Respiratory Diseases	16
Therapeutic Potential of Traditional Chinese Medicine Against Osteoarthritis: Targeting the Wnt Signaling Pathway	16
Astragaloside IV Alleviates Doxorubicin-Induced Cardiotoxicity by Inhibiting Cardiomyocyte Pyroptosis through the SIRT1/NLRP3 Pathway	16
Pharmacological Effects of a Ginseng-Containing Chinese Medicine Formula in Treating Hepatocellular Carcinoma Based on Comprehensive Bioinformatics and Experimental Validation	16
Curcumin Analog L48H37 Induces Apoptosis in Human Oral Cancer Cells by Activating Caspase Cascades and Downregulating the Inhibitor of Apoptosis Proteins through JNK/p38 Signaling	15
Advances in the Application of Traditional Chinese Medicine Using Artificial Intelligence: A Review	15
Ginsenoside Rg5 Improves Sleep by Regulating Energy Metabolism in Sleep-Deprived Rats	15
Acupuncture: A Review of the Safety and Adverse Events and the Strategy of Potential Risk Prevention	15
Regulation of Traditional Chinese Medicine Gut Microbiota Short-Chain Fatty Acid Axis in Type 2 Diabetes Management: A Review	15
Research Progress of Chinese Medicine in the Regulation of Liver Fibrosis-Related Signaling Pathways	15
Molecular Mechanisms of Traditional Chinese Medicine in Treating Osteoarthritis	14
Therapeutic Effects ofAlisma orientaleand its Active Constituents on Cardiovascular Disease and Obesity	14
CORRIGENDUM: Protective Effects of Ginsenosides on 17α-Ethynyelstradiol-Induced Intrahepatic Cholestasis via Anti-Oxidative and Anti-Inflammatory Mechanisms in Rats	14
Ginsenoside Rk1 Ameliorates ER Stress-Induced Apoptosis through Directly Activating IGF-1R in Mouse Pancreatic β-Cells and Diabetic Pancreas	14
Chinese Medicine in Regulating Immune Balance for the Treatment of Autoimmune Diseases	13
Mechanistic Role ofScutellaria baicalensisGeorgi in Breast Cancer Therapy	13
Astragaloside I from Astragalus Attenuates Diabetic Kidney Disease by Regulating HDAC3/Klotho/TGF-β1 Loop	13
Triterpenoid Compounds from Cyclocarya paliurus: A Review of Their Phytochemistry, Quality Control, Pharmacology, and Structure–Activity Relationship	13
Anticancer Effects of Morusin in Prostate Cancer via Inhibition of Akt/mTOR Signaling Pathway	13

Research Progress on Traditional Chinese Medicine in Regulating Inflammatory Pathways of the Gut–Kidney Axis in Diabetic Kidney Disease	13
The Role ofGynostemma pentaphyllumin Regulating Hyperlipidemia	13
Research Progress in Traditional Chinese Medicine for the Treatment of Breast Cancer	13
Traditional Chinese Medicine Formulae and Chinese Patent Medicines for the Treatment of Diabetic Kidney Disease: Efficacies and Mechanisms	13
Chicoric Acid Presented NLRP3-Mediated Pyroptosis through Mitochondrial Damage by PDPK1 Ubiquitination in an Acute Lung Injury Model	13
Application of Large Language Models in Traditional Chinese Medicine: A State-of-the-Art Review	12
Advances and Perspectives on the Anti-Fibrotic Mechanisms of the Quercetin	12
Isoliquiritigenin Inhibits Oral Squamous Cell Carcinoma and Overcomes Chemoresistance by Destruction of Survivin	12
Therapeutic Potentials of Medicinal Leech in Chinese Medicine	12
Sanguinarine Inhibits Gastric Cancer Progression by Targeting the NOS2/SOD1 Axis to Promote Ferroptosis	12
Effects of Chinese Medicine on Pyroptosis in Coronary Heart Disease	12
Baicalin Blocks Colon Cancer Cell Cycle and Inhibits Cell Proliferation through miR-139-3p Upregulation by Targeting CDK16	12
Bergenin Inhibits Tumor Growth and Overcomes Radioresistance by Targeting Aerobic Glycolysis	12
Veratramine Inhibits the Cell Cycle Progression, Migration, and Invasion via ATM/ATR Pathway in Androgen-Independent Prostate Cancer	12
Taraxacum: A Review of Ethnopharmacology, Phytochemistry and Pharmacological Activity	12
Pharmacokinetics and Biological Activities of Notoginsenoside R1: A Systematical Review	11
Glycyrrhizin and the Related Preparations: An Inspiring Resource for the Treatment of Liver Diseases	11
Application of Traditional Chinese Medicine in Alzheimer’s Disease Treatment: A Focus on the Wnt/β-Catenin Pathway	11
Unraveling the Mechanisms of Active Saponins from Rhizoma Anemarrhenae Against Ferroptosis in Alzheimer’s Disease: Integrating Network Pharmacology, Cell Membrane Chromatography, and Experiment	11
Gardenia jasminoidesExtract GJ-4 Alleviates Memory Deficiency of Vascular Dementia in Rats through PERK-Mediated Endoplasmic Reticulum Stress Pathway	11
Chlorogenic Acid Ameliorates Acetaminophen-Induced Liver Injury Through AMPK/mTOR/ULK1-Mediated Autophagy Activation	11
Flavonoids from Radix Puerariae Alleviated Alcoholic Liver Disease via PI3K/AKT Signaling Pathway	11
Botany, Traditional Use, Phytochemistry, Pharmacology and Clinical Applications of Rhubarb (Rhei Radix et Rhizome): A Systematic Review	11
Astragaloside IV Ameliorates Colonic Adenomatous Polyps Development by Orchestrating Gut Bifidobacterium and Serum Metabolome	11
The Phytochemistry of Ganoderma Species and their Medicinal Potentials	11
Panax notoginseng Saponins Activate Nuclear Factor Erythroid 2-Related Factor 2 to Inhibit Ferroptosis and Attenuate Inflammatory Injury in Cerebral Ischemia–Reperfusion	11
Triptolide from Tripterygium wilfordii Suppresses Glycolysis and Induces Cuproptosis via the HK2/DLAT Signaling Pathway in Colorectal Cancer	10
Therapeutic Targets and Natural Product Screening for Cognitive Impairments Associated with Ferroptosis in Wilson’s Disease	10
Traditional Chinese Medicine: A Promising Treatment Option for Intestinal Fibrosis	10
Effects of Curcuminoids and Surfactant-Formulated Curcumin on Chemo-Resistant Colorectal Cancer	10
Ferroptosis in Endometriosis: Traditional Chinese Medicine Interventions and Mechanistic Insights	10
Calycosin Enhances Heat Shock Related-Proteins in H9c2 Cells to Modulate Survival and Apoptosis against Heat Shock	10
Acupuncture for Rheumatoid Arthritis Treatment: Biological Mechanisms of Anti-Inflammation and Analgesia	10
Targeting Autophagy with Geniposide Ameliorates Atherosclerosis in ApoE−∕− Mice	10
Schisanhenol Attenuates OxLDL-Induced Endothelial Dysfunction via an AMPK-Dependent Mechanism	10
Electroacupuncture Reprograms Gut Microbiota and Confers Cerebral Protection After Stroke through Enhanced Regulatory T Cell Response	10
Osthole, a Coumarin from Cnidium monnieri: A Review on Its Pharmacology, Pharmacokinetics, Safety, and Innovative Drug Delivery Platforms	10
Red Yeast Rice and Statin Therapy in Patients with Hypercholesterolemia and the Comorbidities: A Retrospective Cohort Study on Lipid-Lowering Effects and Cardiovascular Outcomes	10
Traditional Chinese Herbal Medicine for Allergic Diseases: A Review	10
Trends and Characteristics of the Whole-Grain Diet	10
Chinese Medicine for Non-Alcoholic Fatty Liver Disease: Targeting Key Signaling Pathways	10
Bufalin Inhibits Tumorigenesis and SREBP-1-Mediated Lipogenesis in Hepatocellular Carcinoma via Modulating the ATP1A1/CA2 Axis	10
Traditional Chinese Medicine for Cancer Treatment	9
Narciclasine Induces Caspase Cascade Activation and Cell Apoptosis via JNK Signaling in Oral Cancer	9
Paeoniflorin Alleviates Metabolic Dysfunction-Associated Fatty Liver Disease by Targeting STING-Mediated Pyroptosis via Inhibiting the NLRP3 Inflammasome	9
A Review of Traditional Chinese Medicine for Triple Negative Breast Cancer and the Pharmacological Mechanisms	9
Valeriana Jatamansi: An Overview of Phytochemistry, Pharmacology, Clinical Prospects, and Network Analysis of Drug Targets	9
Curcumol Reduces Aerobic Glycolysis and Overcomes Chemoresistance by Inducing Cdh1-Mediated Skp2 Ubiquitination	9
The Effectiveness of Acupuncture for Low Back Pain: An Umbrella Review and Meta-Analysis	9
ERRATUM: Paris polyphylla Suppresses Proliferation and Vasculogenic Mimicry of Human Osteosarcoma Cells and Inhibits Tumor Growth	9
Amelioration of Lung Fibrosis by Total Flavonoids of Astragalus via Inflammatory Modulation and Epithelium Regeneration	9
Role of Traditional Chinese Medicine in Lung Cancer Management: A Review	9
Rutaecarpine Alleviates Early Brain Injury-Induced Inflammatory Response Following Subarachnoid Hemorrhage via SIRT6/NF-κB Pathway	9
Astragalus membranaceus Polysaccharide Regulates Small Intestinal Microbes and Activates IL-22 Signal Pathway to Promote Intestinal Stem Cell Regeneration in Aging Mice	9
Ginkgo biloba : The Traditional Use, Phytochemistry, Pharmacology, and Therapeutic Applications	9
The Effectiveness of Traditional Chinese Medicine in Treating Malignancies via Regulatory Cell Death Pathways and the Tumor Immune Microenvironment: A Review of Recent Advances	9
The Pharmacology and Toxicology of Ginkgolic Acids: Secondary Metabolites from Ginkgo biloba	9
Cordycepin: A Promising Anticancer Compound from Traditional Chinese Medicine	8
Effects of Resveratrol on Pulmonary Fibrosis via TGF-β/Smad/ERK Signaling Pathway	8
Eugenol Exerted Significant Anti-Oxidant and Anti-Inflammatory Effects on Experimental Colitis via Directly Acting on PPAR-γ	8
The Role of Traditional Chinese Medicine in the Management of Cervical Cancer	8
Renoprotective Effect of Isoorientin in Diabetic Nephropathy via Activating Autophagy and Inhibiting the PI3K-AKT-TSC2-mTOR Pathway	8
Berberine Metabolites Stimulate GLP-1 Secretion by Alleviating Oxidative Stress and Mitochondrial Dysfunction	8
Research Progress in Ulcerative Colitis: The Role of Traditional Chinese Medicine on Gut Microbiota and Signaling Pathways	8
A Novel Paradigm Defines Functional Molecule Clusters for an Anti-Alzheimer’s Disease Recipe from Traditional Chinese Medicine	8
Gut Microbiota Regulation by Acupuncture and Moxibustion: A Systematic Review and Meta-Analysis	8
Pharmacological Benefits and Underlying Mechanisms of Salvia miltiorrhiza against Molecular Pathology of Various Liver Diseases: A Review	8
Ginsenoside Re Attenuates Cisplatin-Induced Intestinal Toxicity via Suppressing GSK-3β-Dependent Wnt/β-Catenin Signaling Pathway In Vivo and In Vitro	8
The Role of Traditional Chinese Medicine in the Management of Nonalcoholic Fatty Liver Disease: Targeting Gut Microbiome	8
Notoginsenoside R1 Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Apoptosis via Activating Wnt/β-Catenin Signaling	7
Pharmacological Effects of Licorice ( Glycyrrhiza spp.) and Its Bioactive Constituents: The Perspective of Intestinal Microbiota	7
Traditional Chinese Medicine for Alzheimer’s Disease: A Systematic Review and Meta-Analysis	7
Application of Panax ginseng in the Treatment of Chronic Airway Diseases	7
Phytochemical Insights into Panax Genus Metabolites: Evidence-Based Fatigue Intervention via Ethnopharmacological and Biomedical Perspectives	7
A Comprehensive Review of Licorice: The Preparation, Chemical Composition, Bioactivities and Its Applications	7
Total Flavonoids of Astragalus Inhibit Activated CD4+ T Cells and Regulate Differentiation of Th17/Th1/Treg Cells in Experimental Autoimmune Encephalomyelitis Mice by JAK/STAT and NFκB Signaling Pathw	7
Total Saponins of Panax notoginseng Leaves Alleviate Vascular Dementia via the Gut–Brain Axis	7
Ginkgo biloba and Its Chemical Components in the Management of Alzheimer’s Disease	7
Anti-Inflammatory and Anti-oxidative Effects of Puerarin in Postmenopausal Cardioprotection: Roles of Akt and Heme Oxygenase-1	7
Apigenin Suppresses Innate Immune Responses and Ameliorates Lipopolysaccharide-Induced Inflammation via Inhibition of STING/IRF3 Pathway	6

Effects and Mechanistic Role of Mulberry Leaves in Treating Diabetes and its Complications	6
Berberine Alleviates Ischemic Brain Injury by Enhancing Autophagic Flux via Facilitation of TFEB Nuclear Translocation	6
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-κB Pathways	6
Sophora alopecuroides Alleviates Neuroinflammation and Oxidative Damage of Parkinson’s Disease In Vitro and In Vivo	6
Acupuncture for Fibromyalgia: A Review Based on Multidimensional Evidence	6
Therapeutic Effects of Natural Products in the Treatment of Chronic Diseases: The Role in Regulating KEAP1–NRF2 Pathway	6
Curcumin for the Treatment of Inflammatory Bowel Disease: From Mechanism to Clinic	6
Study on the Chemical Constituents, Pharmacological Activities, and Clinical Application of Taxus	6
Review on Processing Methods of Toxic Chinese Materia Medica and the Related Mechanisms of Action	6
Acupuncture and Moxibustion for Inflammatory Bowel Disease: Regulatory Mechanisms Revealed by Microbiome and Metabolomic Analysis	6
Cancer Pain Management with Traditional Chinese Medicine: Current Status and Future Perspectives	6
Effectiveness of Chinese Herbal Medicine in Patients with COVID-19 During the Omicron Wave in Hong Kong: A Retrospective Case-Controlled Study	6
Efficacy and Safety of Glycyrrhizic Acid in Treatment of Autoimmune Hepatitis	6
The Pharmacological Effects of Gastrodin and the Progress in the Treatment of Neurological Disorders	6
Cannabidiol Reprograms Glucose Metabolism in Colorectal Adenocarcinoma by Targeting HIF-1α/LDHA Pathway	6
Chinese Herbal Medicine, Alternative or Complementary, for Endometriosis-Associated Pain: A Meta-Analysis	6
Korean Red Ginseng Marc-Derived Gintonin Improves Alzheimer’s Cognitive Dysfunction by Upregulating LPAR1	6
The Role of Chinese Medicine in the Treatment of Chronic Hepatitis B	6
Integrated Metabonomic Study on the Relationship between Medicinal Properties and Efficacy ofRehmanniae Radix	6
The Role of Traditional Chinese Medicines in the Treatment of Osteoporosis	6