American Journal of Chinese Medicine

Article	Citations
Chinese Materia Medica in Treating Depression: The Role of Intestinal Microenvironment	68
Astragalus membranaceus as a Drug Candidate for Inflammatory Bowel Disease: The Preclinical Evidence	63
Umbelliferone Inhibits Migration, Invasion and Inflammation of Rheumatoid Arthritis Fibroblast-Like Synoviocytes and Relieves Adjuvant-Induced Arthritis in Rats by Blockade of Wnt/β-Catenin Signaling	49
Ginsenoside Rg6 Improves Cisplatin Resistance in Epithelial Ovarian Cancer Cells via Suppressing Fucosylation and Inducing Autophagy	49
Solasonine Inhibits Cancer Stemness and Metastasis by Modulating Glucose Metabolism via Wnt/β-Catenin/Snail Pathway in Osteosarcoma	46
Chinese Medicine-Derived Salvianolic Acid B for Disease Therapy: A Scientometric Study	44
Research Progress of Chinese Medicine in Treating Chronic Liver Disease by Regulating Autophagy	41
Effects of Crocin on CCL2/CCR2 Inflammatory Pathway in Monocrotaline-Induced Pulmonary Arterial Hypertension Rats	40
Mechanism of Acupuncture in Treating Obesity: Advances and Prospects	35
Cornel Iridoid Glycoside and Its Effective Component Regulate ATPase Vps4A/JNK to Alleviate Autophagy Deficit with Autophagosome Accumulation	34
Arteannuin B Enhances the Effectiveness of Cisplatin in Non-Small Cell Lung Cancer by Regulating Connexin 43 and MAPK Pathway	30
Nrf2-Dependent Protective Effect of Paeoniflorin on α-Naphthalene Isothiocyanate-Induced Hepatic Injury	30
Probiotic Fermentation of Herbal Medicine: Progress, Challenges, and Opportunities	25
Deer Velvet Antler Extracts Exert Anti-Inflammatory and Anti-Arthritic Effects on Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes and Distinct Mouse Arthritis	25
Curcumin-Pretreated Adipose-Derived Stem Cells Enhance the Neuroprotective Ability to Repair Rheumatoid Arthritis-Induced Damage in the Rat Brain	25
Multidirectional Intervention of Chinese Herbal Medicine in the Prevention and Treatment of Atherosclerosis: From Endothelial Protection to Immunomodulation	23
Formononetin Alleviates Ischemic Acute Kidney Injury by Regulating Macrophage Polarization through KLF6/STAT3 Pathway	23
Regulating the Imbalance of Gut Microbiota by Smilax china L. Polyphenols to Alleviate Dextran Sulfate Sodium-induced Inflammatory Bowel Diseases	22
20(S)-Protopanaxadiol fromPanax ginsengInduces Apoptosis and Autophagy in Gastric Cancer Cells by Inhibiting Src	21
Ginsenoside Rb1 Relieves Cellular Senescence and Pulmonary Fibrosis by Promoting NRF2/QKI/SMAD7 Axis	21
Liquiritigenin, an Active Ingredient of Liquorice, Alleviates Acute Kidney Injury by VKORC1-Mediated Ferroptosis Inhibition	20
The Role of Traditional Chinese Medicine in Cancer Immunotherapy: Current Status and Future Directions	20
Efficacy of Oriental Exercises for Non-Motor Symptoms and Quality of Life in Parkinson’s Disease: A Systematic Review and Meta-Analysis	20
Mangiferin Protects against Angiotensin-II-Enhanced Hypertrophic Markers and Apoptosis in H9c2 Cardiomyocytes	20
Ginsenoside Rd Attenuates Myocardial Ischemia/Reperfusion Injury by Inhibiting Inflammation and Apoptosis through PI3K/Akt Signaling Pathway	20

Catalpol from Rehmannia glutinosa Targets Nrf2/NF-κB Signaling Pathway to Improve Renal Anemia and Fibrosis	20
Chinese Medicine for the Treatment of Liver Cirrhosis: The Mechanism of Cellular Autophagy	19
Individualized Diagnosis and Prescription in Traditional Medicine: Decision-Making Process Analysis and Machine Learning-Based Analysis Tool Development	19
Traditional Chinese Patent Medicine in the Treatment of Alzheimer’s Disease: A Systematic Review and Network Meta-Analysis	19
Gut Flora Mediates the Rapid Tolerance of Electroacupuncture on Ischemic Stroke by Activating Melatonin Receptor through Regulating Indole-3-Propionic Acid	18
Cinnamon for Metabolic Diseases and Their Cardiovascular and Hepatic Complications: A Mechanistic Review	17
Traditional Chinese Medicine in Osteoporosis Intervention and the Related Regulatory Mechanism of Gut Microbiome	17
Xanthohumol Promotes Skp2 Ubiquitination Leading to the Inhibition of Glycolysis and Tumorigenesis in Ovarian Cancer	17
Amygdalin Induced Mitochondria-Mediated Apoptosis of Lung Cancer Cells via Regulating NFκB-1/NFκB Signaling Cascadein Vitroandin Vivo	17
Research Progress on the Antitumor Molecular Mechanism of Ginsenoside Rh2	16
Salvianolic Acid Ameliorates Pressure Overload-Induced Cardiac Endothelial Dysfunction via Activating HIF1α/HSF1/CD31 Pathway	16
Research Progress of Immunomodulation on Anti-COVID-19 and the Effective Components from Traditional Chinese Medicine	15
Perioperative Acupuncture Optimizes Surgical Outcomes: Theory, Clinical Practice and Future Perspectives	15
Prenylated Flavonoids in Sophora flavescens: A Systematic Review of Their Phytochemistry and Pharmacology	15
Andrographolide Inhibits Lipotoxicity-Induced Activation of the NLRP3 Inflammasome in Bone Marrow-Derived Macrophages	15
Ginsenoside Rh2 Regulates the CFAP20DC-AS1/MicroRNA-3614-3p/BBX and TNFAIP3 Axis to Induce Apoptosis in Breast Cancer Cells	15
The Changing Global Landscape in the Development of Artemisinin-Based Treatments: A Clinical Trial Perspective	15
Smilax china Polyphenols Stimulate Browning via β3-Adrenergic Receptor/AMP-Activated Protein Kinase α Signaling Pathway in 3T3-L1 Adipocytes	15
Targeting Ferroptosis in Cancer by Natural Products: An Updated Review	15
IL-10-dependent Effect of Chinese Medicine Abelmoschus manihot on Alleviating Intestinal Inflammation and Modulating Gut Microbiota	15
ERRATUM — The Effects of Patchouli Alcohol on Diarrhea-Predominant Irritable Bowel Syndrome are Correlated with Phenotypic Plasticity in Myenteric Neurons and the Targeted Regulation of Myosin Va	14
Research Progress of Traditional Chinese Medicine Monomers in Reversing Multidrug Resistance of Breast Cancer	14
The Pharmacological Rationales and Molecular Mechanisms ofGanoderma lucidumPolysaccharides for the Therapeutic Applications of Multiple Diseases	14
Ruscogenin Alleviates Myocardial Ischemia via Myosin IIA-Dependent Mitochondrial Fusion and Fission Balance	14
New Perspectives on Chinese Medicine in Treating Hepatic Fibrosis: Lipid Droplets in Hepatic Stellate Cells	14
Coptis chinensis-Induced Changes in Metabolomics and Gut Microbiota in Rats	14
Protective Effects and Therapeutics of Ginsenosides for Improving Endothelial Dysfunction: From Therapeutic Potentials, Pharmaceutical Developments to Clinical Trials	14
Qigong and Tai Chi on Human Health: An Overview of Systematic Reviews	14
Cardioprotective Effects of Tetrahydropalmatine on Acute Myocardial Infarction in Rats	13
Efficacy and Mechanisms of Natural Products as Therapeutic Interventions for Chronic Respiratory Diseases	13
Therapeutic Potential of Traditional Chinese Medicine Against Osteoarthritis: Targeting the Wnt Signaling Pathway	13
A Clinical Study on the Relationship Among Insomnia, Tongue Diagnosis, and Oral Microbiome	13
The Role ofGynostemma pentaphyllumin Regulating Hyperlipidemia	12
Advances in the Application of Traditional Chinese Medicine Using Artificial Intelligence: A Review	12
Anticancer Effects of Morusin in Prostate Cancer via Inhibition of Akt/mTOR Signaling Pathway	12
Research Progress of Chinese Medicine in the Regulation of Liver Fibrosis-Related Signaling Pathways	12
Pharmacological Effects of a Ginseng-Containing Chinese Medicine Formula in Treating Hepatocellular Carcinoma Based on Comprehensive Bioinformatics and Experimental Validation	12
Curcumin Analog L48H37 Induces Apoptosis in Human Oral Cancer Cells by Activating Caspase Cascades and Downregulating the Inhibitor of Apoptosis Proteins through JNK/p38 Signaling	12
Triterpenoid Compounds from Cyclocarya paliurus: A Review of Their Phytochemistry, Quality Control, Pharmacology, and Structure–Activity Relationship	12
Astragaloside IV Alleviates Doxorubicin-Induced Cardiotoxicity by Inhibiting Cardiomyocyte Pyroptosis through the SIRT1/NLRP3 Pathway	12
Ginsenoside Rg5 Improves Sleep by Regulating Energy Metabolism in Sleep-Deprived Rats	12
Advances in Anti-Osteoporosis Polysaccharides Derived from Medicinal Herbs and Other Edible Substances	11
Ginsenoside Rk1 Ameliorates ER Stress-Induced Apoptosis through Directly Activating IGF-1R in Mouse Pancreatic β-Cells and Diabetic Pancreas	11
Veratramine Inhibits the Cell Cycle Progression, Migration, and Invasion via ATM/ATR Pathway in Androgen-Independent Prostate Cancer	11
Bergenin Inhibits Tumor Growth and Overcomes Radioresistance by Targeting Aerobic Glycolysis	11
Saponins From Platycodon grandiflorum Reduces Cisplatin-Induced Intestinal Toxicity in Mice through Endoplasmic Reticulum Stress-Activated Apoptosis	11
Therapeutic Effects ofAlisma orientaleand its Active Constituents on Cardiovascular Disease and Obesity	11
Acupuncture: A Review of the Safety and Adverse Events and the Strategy of Potential Risk Prevention	11
Isoliquiritigenin Inhibits Oral Squamous Cell Carcinoma and Overcomes Chemoresistance by Destruction of Survivin	11
Zingiber officinale: A Systematic Review of Botany, Phytochemistry and Pharmacology of Gut Microbiota-Related Gastrointestinal Benefits	11

Target-Specific Drug Discovery of Natural Products against SARS-CoV-2 Life Cycle and Cytokine Storm in COVID-19	11
Mechanistic Role ofScutellaria baicalensisGeorgi in Breast Cancer Therapy	11
Therapeutic Potentials of Medicinal Leech in Chinese Medicine	11
Astragaloside I from Astragalus Attenuates Diabetic Kidney Disease by Regulating HDAC3/Klotho/TGF-β1 Loop	11
Notoginsenoside R1, An Active Compound from Panax notoginseng, Inhibits Hepatic Stellate Cell Activation and Liver Fibrosis via MAPK Signaling Pathway	11
Gardenia jasminoidesExtract GJ-4 Alleviates Memory Deficiency of Vascular Dementia in Rats through PERK-Mediated Endoplasmic Reticulum Stress Pathway	10
Pharmacokinetics and Biological Activities of Notoginsenoside R1: A Systematical Review	10
Salidroside Ameliorates Ischemia-Induced Neuronal Injury through AMPK Dependent and Independent Pathways to Maintain Mitochondrial Quality Control	10
The Phytochemistry of Ganoderma Species and their Medicinal Potentials	10
Taraxacum: A Review of Ethnopharmacology, Phytochemistry and Pharmacological Activity	10
Traditional Chinese Medicine: A Promising Treatment Option for Intestinal Fibrosis	10
Astragaloside IV Ameliorates Colonic Adenomatous Polyps Development by Orchestrating Gut Bifidobacterium and Serum Metabolome	10
Panax notoginseng Saponins Activate Nuclear Factor Erythroid 2-Related Factor 2 to Inhibit Ferroptosis and Attenuate Inflammatory Injury in Cerebral Ischemia–Reperfusion	10
Traditional Chinese Herbal Medicine for Allergic Diseases: A Review	10
Effects of Chinese Medicine on Pyroptosis in Coronary Heart Disease	10
Falcarindiol Stimulates Apoptotic and Autophagic Cell Death to Attenuate Cell Proliferation, Cell Division, and Metastasis through the PI3K/AKT/mTOR/p70S6K Pathway in Human Oral Squamous Cell Carcinom	10
Botany, Traditional Use, Phytochemistry, Pharmacology and Clinical Applications of Rhubarb (Rhei Radix et Rhizome): A Systematic Review	10
Effect and Mechanism of Qingfei Paidu Decoction in the Management of Pulmonary Fibrosis and COVID-19	10
Glycyrrhizin and the Related Preparations: An Inspiring Resource for the Treatment of Liver Diseases	10
Baicalin Blocks Colon Cancer Cell Cycle and Inhibits Cell Proliferation through miR-139-3p Upregulation by Targeting CDK16	10
Chlorogenic Acid Ameliorates Acetaminophen-Induced Liver Injury Through AMPK/mTOR/ULK1-Mediated Autophagy Activation	10
Chicoric Acid Presented NLRP3-Mediated Pyroptosis through Mitochondrial Damage by PDPK1 Ubiquitination in an Acute Lung Injury Model	10
Neferine Suppresses Experimental Colitis-Associated Colorectal Cancer by Inhibition of NF-κB p65 and STAT3	10
Targeting Autophagy with Geniposide Ameliorates Atherosclerosis in ApoE−∕− Mice	9
Bufalin Inhibits Tumorigenesis and SREBP-1-Mediated Lipogenesis in Hepatocellular Carcinoma via Modulating the ATP1A1/CA2 Axis	9
Red Yeast Rice and Statin Therapy in Patients with Hypercholesterolemia and the Comorbidities: A Retrospective Cohort Study on Lipid-Lowering Effects and Cardiovascular Outcomes	9
Trends and Characteristics of the Whole-Grain Diet	9
Lupeol Alleviates Myocardial Ischemia-Reperfusion Injury in Rats by Regulating NF-κB and Nrf2 Pathways	9
Ferroptosis in Endometriosis: Traditional Chinese Medicine Interventions and Mechanistic Insights	9
Effects of Curcuminoids and Surfactant-Formulated Curcumin on Chemo-Resistant Colorectal Cancer	9
Curcumol Reduces Aerobic Glycolysis and Overcomes Chemoresistance by Inducing Cdh1-Mediated Skp2 Ubiquitination	9
Schisanhenol Attenuates OxLDL-Induced Endothelial Dysfunction via an AMPK-Dependent Mechanism	9
Calycosin Enhances Heat Shock Related-Proteins in H9c2 Cells to Modulate Survival and Apoptosis against Heat Shock	9
Traditional Chinese Medicine for Cancer Treatment	9
Osthole, a Coumarin from Cnidium monnieri: A Review on Its Pharmacology, Pharmacokinetics, Safety, and Innovative Drug Delivery Platforms	9
Therapeutic Targets and Natural Product Screening for Cognitive Impairments Associated with Ferroptosis in Wilson’s Disease	9
The Pharmacology and Toxicology of Ginkgolic Acids: Secondary Metabolites from Ginkgo biloba	8
Ginsenoside Rg5: A Review of Anticancer and Neuroprotection with Network Pharmacology Approach	8
Mechanisms of Danggui Buxue Tang on Hematopoiesis via Multiple Targets and Multiple Components: Metabonomics Combined with Database Mining Technology	8
Rutaecarpine Alleviates Early Brain Injury-Induced Inflammatory Response Following Subarachnoid Hemorrhage via SIRT6/NF-κB Pathway	8
Proapoptotic Effect of Icariin on Human Ovarian Cancer Cells via the NF-κB/PI3K-AKT Signaling Pathway: A Network Pharmacology-Directed Experimental Investigation	8
Role of Traditional Chinese Medicine in Lung Cancer Management: A Review	8
Amelioration of Lung Fibrosis by Total Flavonoids of Astragalus via Inflammatory Modulation and Epithelium Regeneration	8
Efficacy and Safety of Chinese Medicine for COVID-19: A Systematic Review and Meta-Analysis	8
Astragalus membranaceus Polysaccharide Regulates Small Intestinal Microbes and Activates IL-22 Signal Pathway to Promote Intestinal Stem Cell Regeneration in Aging Mice	8
The Effectiveness of Acupuncture for Low Back Pain: An Umbrella Review and Meta-Analysis	8
Research Progress in Ulcerative Colitis: The Role of Traditional Chinese Medicine on Gut Microbiota and Signaling Pathways	8
The Effectiveness of Traditional Chinese Medicine in Treating Malignancies via Regulatory Cell Death Pathways and the Tumor Immune Microenvironment: A Review of Recent Advances	7
Gambogic Acid Induces HO-1 Expression and Cell Apoptosis through p38 Signaling in Oral Squamous Cell Carcinoma	7
A Novel Paradigm Defines Functional Molecule Clusters for an Anti-Alzheimer’s Disease Recipe from Traditional Chinese Medicine	7
Curcumin Inhibits T Follicular Helper Cell Differentiation in Mice with Dextran Sulfate Sodium (DSS)-Induced Colitis	7
Dietary Supplements for Pain Relief in Patients with Fibromyalgia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials	7
Ginsenoside Re Attenuates Cisplatin-Induced Intestinal Toxicity via Suppressing GSK-3β-Dependent Wnt/β-Catenin Signaling Pathway In Vivo and In Vitro	7
A Review of Traditional Chinese Medicine for Triple Negative Breast Cancer and the Pharmacological Mechanisms	7
Traditional Chinese Medicine for COVID-19: A Network Meta-Analysis and Systematic Review	7
Integrative Analysis of the Gut Microbiota and Metabolome in Obese Mice with Electroacupuncture by 16S rRNA Gene Sequencing and HPLC–MS-based Metabolic Profiling	7
Gut Microbiota Regulation by Acupuncture and Moxibustion: A Systematic Review and Meta-Analysis	7
In SilicoPrediction of Andrographolide Dosage Regimens for COVID-19 Treatment	6
Efficacy and Safety of Shengmai Preparation Combined with Western Medicine for Coronary Heart Disease: A Systematic Review and Meta-Analysis	6
Renoprotective Effect of Isoorientin in Diabetic Nephropathy via Activating Autophagy and Inhibiting the PI3K-AKT-TSC2-mTOR Pathway	6
A Review of Traditional Chinese Medicine on Treatment of Diabetic Nephropathy and the Involved Mechanisms	6
Pharmacological Benefits and Underlying Mechanisms of Salvia miltiorrhiza against Molecular Pathology of Various Liver Diseases: A Review	6
Neuroprotective Effects ofAlpinia oxyphyllaMiq against Mitochondria-Related Apoptosis by the Interactions between Upregulated p38 MAPK Signaling and Downregulated JNK Signaling in the Subacute	6
Identifying Dose Components of Manual Acupuncture to Determine the Dose–Response Relationship of Acupuncture Treatment: A Systematic Review	6
Berberine Metabolites Stimulate GLP-1 Secretion by Alleviating Oxidative Stress and Mitochondrial Dysfunction	6
The Effects of Patchouli Alcohol on Diarrhea-Predominant Irritable Bowel Syndrome are Correlated with Phenotypic Plasticity in Myenteric Neurons and the Targeted Regulation of Myosin Va	6
Effects of Resveratrol on Pulmonary Fibrosis via TGF-β/Smad/ERK Signaling Pathway	6
Apigenin Suppresses Innate Immune Responses and Ameliorates Lipopolysaccharide-Induced Inflammation via Inhibition of STING/IRF3 Pathway	6
Astragalus Total Saponins Ameliorate Peritoneal Fibrosis by Promoting Mitochondrial Synthesis and Inhibiting Apoptosis	6
The Role of Traditional Chinese Medicine in the Management of Cervical Cancer	6
A Comprehensive Review of Licorice: The Preparation, Chemical Composition, Bioactivities and Its Applications	6
Ginkgo biloba and Its Chemical Components in the Management of Alzheimer’s Disease	6
Anti-Inflammatory and Anti-oxidative Effects of Puerarin in Postmenopausal Cardioprotection: Roles of Akt and Heme Oxygenase-1	5
Efficacy and Safety of Glycyrrhizic Acid in Treatment of Autoimmune Hepatitis	5
Integrated Metabonomic Study on the Relationship between Medicinal Properties and Efficacy ofRehmanniae Radix	5
Total Flavonoids of Astragalus Inhibit Activated CD4+ T Cells and Regulate Differentiation of Th17/Th1/Treg Cells in Experimental Autoimmune Encephalomyelitis Mice by JAK/STAT and NFκB Signaling Pathw	5
The Role of Traditional Chinese Medicines in the Treatment of Osteoporosis	5
Traditional Chinese Medicine for Alzheimer’s Disease: A Systematic Review and Meta-Analysis	5
Effectiveness of Chinese Herbal Medicine in Patients with COVID-19 During the Omicron Wave in Hong Kong: A Retrospective Case-Controlled Study	5
Therapeutic Effects of Natural Products in the Treatment of Chronic Diseases: The Role in Regulating KEAP1–NRF2 Pathway	5

Nanotechnology-Based Drug Delivery System for Anticancer Active Ingredients from Traditional Chinese Medicines: A Review	5
Tanshinone IIA Microemulsion Protects against Cerebral Ischemia Reperfusion Injury via Regulating H3K18ac and H4K8acIn VivoandIn Vitro	5
Tanshinone IIA: New Perspective on the Anti-Tumor Mechanism of A Traditional Natural Medicine	5
Study on the Chemical Constituents, Pharmacological Activities, and Clinical Application of Taxus	5