Immunobiology

Article	Citations
Endothelial injury and thrombotic microangiopathy in COVID-19: Treatment with the lectin-pathway inhibitor narsoplimab	113
Immunoinformatics-guided designing of epitope-based subunit vaccines against the SARS Coronavirus-2 (SARS-CoV-2)	63
Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies	60
Natural and trained innate immunity against Mycobacterium tuberculosis	51
The role of dectin-1 in health and disease	48
Exploiting the reverse vaccinology approach to design novel subunit vaccines against Ebola virus	39
TIGIT and PD-1 may serve as potential prognostic biomarkers for gastric cancer	36
SARS-CoV-2 attachment to host cells is possibly mediated via RGD-integrin interaction in a calcium-dependent manner and suggests pulmonary EDTA chelation therapy as a novel treatment for COVID 19	33
Butyrate directly decreases human gut lamina propria CD4 T cell function through histone deacetylase (HDAC) inhibition and GPR43 signaling	31
Immunomodulatory significance of natural peptides in mammalians: Promising agents for medical application	28
Dioscin protects against diabetic nephropathy by inhibiting renal inflammation through TLR4/NF-κB pathway in mice	25
Why blood group A individuals are at risk whereas blood group O individuals are protected from SARS-CoV-2 (COVID-19) infection: A hypothesis regarding how the virus invades the human body via ABO(H) b	23
What do we know about the antibody responses to SARS-CoV-2?	23
Quercetin induces an immunoregulatory phenotype in maturing human dendritic cells	22
Changes in macrophage inflammatory protein-1 (MIP-1) family members expression induced by traumatic brain injury in mice	21
Beta-naphthoflavone inhibits LPS-induced inflammation in BV-2 cells via AKT/Nrf-2/HO-1-NF-κB signaling axis	20
Advances in immunotherapy for the treatment of spinal cord injury	20
Immunoinformatics approach for a novel multi-epitope subunit vaccine design against various subtypes of Influenza A virus	19
MiR-183-5p overexpression in bone mesenchymal stem cell-derived exosomes protects against myocardial ischemia/reperfusion injury by targeting FOXO1	18
Inflammasome activation by NLRP1 and NLRC4 in patients with coronary stenosis	17
CCR2 and DPP9 expression in the peripheral blood of COVID-19 patients: Influences of the disease severity and gender	17
Regulatory role of Apelin-13-mediated PI3K/AKT signaling pathway in the glucose and lipid metabolism of mouse with gestational diabetes mellitus	17
The role of macrophages type 2 and T-regs in immune checkpoint inhibitor related adverse events	17
MBL deficiency-causing B allele (rs1800450) as a risk factor for severe COVID-19	16
Roles of protein ubiquitination in inflammatory bowel disease	16

A method to differentiate chicken monocytes into macrophages with proinflammatory properties	15
Effects of TNF-α on autophagy of rheumatoid arthritis fibroblast-like synoviocytes and regulation of the NF-κB signaling pathway	15
Acquired decrease of the C3b/C4b receptor (CR1, CD35) and increased C4d deposits on erythrocytes from ICU COVID-19 patients	15
Antigenic sites in SARS-CoV-2 spike RBD show molecular similarity with pathogenic antigenic determinants and harbors peptides for vaccine development	14
The host response to bacterial bone infection involves a local upregulation of several acute phase proteins	14
The mTOR-glycolytic pathway promotes T-cell immunobiology in oral lichen planus	14
GTS-21, an α7nAChR agonist, suppressed the production of key inflammatory mediators by PBMCs that are elevated in COPD patients and associated with impaired lung function	14
Human bone marrow mesenchymal stem cells-derived exosomes protect against nerve injury via regulating immune microenvironment in neonatal hypoxic-ischemic brain damage model	14
Omicron variant infection and the associated immunological scenario	14
LncRNA LINC00184 promotes docetaxel resistance and immune escape via miR-105-5p/PD-L1 axis in prostate cancer	13
BCG immunomodulation: From the ‘hygiene hypothesis’ to COVID-19	13
A review on structural, non-structural, and accessory proteins of SARS-CoV-2: Highlighting drug target sites	13
Altered NK cell receptor repertoire and function of natural killer cells in patients with acute myocardial infarction: A three-month follow-up study	12
Generation of novel trimeric fragments of human SP-A and SP-D after recombinant soluble expression in E. coli	12
Adiponectin and leptin levels in idiopathic pulmonary fibrosis: A new method for BAL and serum assessment	12
Immune induction by adjuvanted Leishmania donovani vaccines against the visceral leishmaniasis in BALB/c mice	11
Complement and COVID-19: Three years on, what we know, what we don't know, and what we ought to know	11
Treatment with inhaled formulation of angiotensin-(1-7) reverses inflammation and pulmonary remodeling in a model of chronic asthma	11
CircEXOC5 promotes ferroptosis by enhancing ACSL4 mRNA stability via binding to PTBP1 in sepsis-induced acute lung injury	11
Estrogen signaling differentially alters iron metabolism in monocytes in an Interleukin 6-dependent manner	10
Induction of CIITA by IFN-γ in macrophages involves STAT1 activation by JAK and JNK	10
The role of CD68+ and CD163+ macrophages in immunopathogenesis of oral lichen planus and oral lichenoid lesions	10
Pyruvate kinase M2 in lung APCs regulates Alternaria-induced airway inflammation	10
Association of interleukin-17 gene polymorphisms with the onset of Rheumatoid Arthritis	10
Mouse bone marrow-derived mesenchymal stem cells acquire immunogenicity concurrent with differentiation to insulin-producing cells	10
Immunomodulatory effects and potential clinical applications of dimethyl sulfoxide	9
PM2.5 induced lung injury through upregulating ROS-dependent NLRP3 Inflammasome-Mediated Pyroptosis	9
M-CSF- and L929-derived macrophages present distinct metabolic profiles with similar inflammatory outcomes	9
Genome interaction of the virus and the host genes and non-coding RNAs in SARS-CoV-2 infection	9
Upregulation of leukemia-induced non-coding activator RNA (LUNAR1) predicts poor outcome in pediatric T-acute lymphoblastic leukemia	9
β2 Integrin Gene (ITGB2) mutation spectra in Pakistani families with leukocyte adhesion deficiency type 1 (LAD1)	9
Benznidazole: Hero or villain of cellular immune response in chronic Chagas disease patients?	9
Bacterial lipoproteins in sepsis	9
α9α10 nicotinic acetylcholine receptors regulate murine bone marrow granulocyte functions	9
Deciphering the balance of IL-6/IL-10 cytokines in severe to critical COVID-19 patients	9
Long non-coding RNA RP11-490M8.1 inhibits lipopolysaccharide-induced pyroptosis of human umbilical vein endothelial cells via the TLR4/NF-κB pathway	8
TEAD4 transcriptional regulates SERPINB3/4 and affect crosstalk between keratinocytes and T cells in psoriasis	8
Anti-complement factor I antibody associated atypical hemolytic uremic syndrome – A new insight for future perspective!	8
Monophosphoryl lipid A directly regulates Th1 cytokine production in human CD4+ T-cells through Toll-like receptor 2 and 4	8
Leukemia derived dendritic cell (DCleu) mediated immune response goes along with reduced (leukemia-specific) regulatory T-cells	8
Preclinical characterization of a Fab-like CD3/CLDN18.2 XFab® bispecific antibody against solid tumors	8
V-set domain containing T-cell activation inhibitor-1 (VTCN1): A potential target for the treatment of autoimmune diseases	8
Atorvastatin inhibits IL-17A, TNF, IL-6, and IL-10 in PBMC cultures from patients with severe rheumatoid arthritis	8
Multinucleated giant cell phenotype in response to stimulation	8
PAF-R on activated T cells: Role in the IL-23/Th17 pathway and relevance to multiple sclerosis	8
Effects of total glucosides of paeony on acute renal injury following ischemia–reperfusion via the lncRNA HCG18/miR-16-5p/Bcl-2 axis	8
Embryonic stem cells-derived exosomes enhance retrodifferentiation of retinal Müller cells by delivering BDNF protein to activate Wnt pathway	7
The PE-PPE Family of Mycobacterium tuberculosis: Proteins in Disguise	7
Fungal β-glucans and mannan stimulate peripheral blood mononuclear cells to cytokine production in Syk-dependent manner	7
Hypoxanthine Guanine Phosphoribosyltransferase expression is negatively correlated with immune activity through its regulation of purine synthesis	7

Trophoblast cell influence on peripheral blood natural killer cell proliferation and phenotype in non-pregnant women and women in early pregnancy	7
Increased levels of the soluble oncostatin M receptor (sOSMR) and glycoprotein 130 (sgp130) in systemic sclerosis patients and associations with clinical parameters	7
Immunogenic efficacy of DNA and protein-based vaccine from a chimeric gene consisting OmpW, TcpA and CtxB, of Vibrio cholerae	7
NK-92 cells change their phenotype and function when cocultured with IL-15, IL-18 and trophoblast cells	7
Exploring Kawasaki disease-specific hub genes revealing a striking similarity of expression profile to bacterial infections using weighted gene co-expression network analysis (WGCNA) and co-expression	7
Linking murine resistance to secondary cystic echinococcosis with antibody responses targeting Echinococcus granulosus tegumental antigens	7
Nanoparticle-induced immune response: Health risk versus treatment opportunity?	7
Transient Foxp3(+) regulatory T-cell depletion enhances protective Th1/Th17 immune response in murine sporotrichosis caused by Sporothrix schenckii	7
Polymorphisms in Toll-like receptors genes changes the host’s immune response and is associated with cervical cancer	6
The interplay of interleukin-17A and breast cancer tumor microenvironment as a novel immunotherapeutic approach to increase tumor immunogenicity	6
Quercetin acts as a novel anti-cancer drug to suppress cancer aggressiveness and cisplatin-resistance in nasopharyngeal carcinoma (NPC) through regulating the yes-associated protein/Hippo signaling pa	6
RNASeq analysis reveals upregulation of complement C3 in the offspring gut following prenatal stress in mice	6
LncRNA OGFRP1 promotes angiogenesis and epithelial-mesenchymal transition in colorectal cancer cells through miR-423-5p/CTCF axis	6
The MHC-II antigen presentation machinery and B7 checkpoint ligands display distinctive patterns correlated with acute myeloid leukaemias blast cells HLA-DR expression	6
Effect of pathogenic crystals on the production of pro- and anti-inflammatory cytokines by different leukocyte populations	6
CCR4+ monocytic myeloid-derived suppressor cells are associated with the increased epithelial-mesenchymal transition in pancreatic adenocarcinoma patients	6
Involvement of Xeroderma Pigmentosum Complementation Group G (XPG) in epigenetic regulation of T-Helper (TH) cell differentiation during breast cancer	6
Cytotoxic activity of human dendritic cells induces RIPK1-dependent cell death	6
Intestinal production of secreted protein acidic and rich in cysteine (SPARC) in patients with ulcerative colitis	6
PPE2 protein of Mycobacterium tuberculosis affects myeloid hematopoiesis in mice	6
Epigenetics in non-classical monocytes support their pro-inflammatory gene expression	6
Low molecular weight cytotoxic components (DAMPs) form the post-COVID-19 syndrome	6
IL-27 regulates IL-4-induced chemokine production in human bronchial epithelial cells	6
An eosinophil-Sos1-RAS axis licenses corticosteroid resistance in patients with allergic rhinitis	6
A young girl with hypogammaglobulinemia and granulomatous hepatitis caused by a novel mutation in ZBTB24 gene: A case based analysis	6
Identification of a novel TLR5 agonist derived from the P97 protein of Mycoplasma hyopneumoniae	6
Selective downregulation of natural killer activating receptors on NK cells and upregulation of PD-1 expression on T cells in children with severe and/or recurrent Herpes simplex virus infections	6
Innate antiviral responses in porcine nasal mucosal explants inoculated with influenza A virus are comparable with responses in respiratory tissues after viral infection	6
Bavachin inhibits IL-4 expression by downregulating STAT6 phosphorylation and GATA-3 expression and ameliorates asthma inflammation in an animal model	6
Immune response modulation by allergen loaded into mesenchymal stem cell-derived exosomes as an effective carrier through sublingual immunotherapy	6
STING mediates SU5416/hypoxia-induced pulmonary arterial hypertension in rats by regulating macrophage NLRP3 inflammasome activation	5
Association of epidermal differentiation complex (EDC) genetic variants with House Dust Mite sensitization in Atopic Dermatitis Patients	5
Reduced frequency and functional potency of CD49d− T regulatory cells in patients with newly diagnosed type 2 diabetes mellitus	5
Novel inflammatory targets for immunotherapies in pediatric patients with trichotillomania	5
ST6GAL1 polymorphisms influence susceptibility and progression of IgA nephropathy in a Chinese Han population	5
Lactobacillus delbrueckii UFV-H2b20 increases IFN-γ production and CD39+CD73+ Treg cell numbers in lungs, and protects mice against experimental allergic asthma	5
Development of dominant epitope-based vaccines encoding Gp63, Kmp-11 and Amastin against visceral leishmaniasis	5
IL-33 synergistically promotes the proliferation of lung cancer cells in vitro by inducing antibacterial peptide LL-37 and proinflammatory cytokines in macrophages	5
Identification of a peptide targeting CD56	5
Macrophage Migration Inhibitory Factor contributes to drive phenotypic and functional macrophages activation in response to Toxoplasma gondii infection	5
Arginase is involved in cervical lesions progression and severity	5
Estrogen receptors in human bladder cells regulate innate cytokine responses to differentially modulate uropathogenic E. coli colonization	5
The Nurr7 agonist Cytosporone B differentially regulates inflammatory responses in human polarized macrophages	5
Diagnosis of radiosensitive severe combined immunodeficiency disease (RS-SCID) by Comet Assay, management of bone marrow transplantation	5
STC1 ameliorates cognitive impairment and neuroinflammation of Alzheimer’s disease mice via inhibition of ERK1/2 pathway	5
Expression profile of MUC1 protein in Pigeon allergens positive asthmatic	5
CCR1 antagonist J-113863 corrects the imbalance of pro- and anti-inflammatory cytokines in a SJL/J mouse model of relapsing-remitting multiple sclerosis	4
Changes in extracellular cytokines in predicting disease severity and final clinical outcome of patients with blunt chest trauma	4
Proportion of B cell subsets and Nrf2 mediated redox regulation in systemic lupus erythematosus patients	4
ERAP1 binds peptide C-termini of different sequences and/or lengths by a common recognition mechanism	4
Post-translational suppression of the high affinity IgE receptor expression on mast cells by an intestinal bacterium	4
Study on the additive protective effect of PGLYRP3 and Bifidobacterium adolescentis Reuter 1963 on severity of DSS-induced colitis in Pglyrp3 knockout (Pglyrp3 −/−) and wild-type (WT) mice	4
Pan genome based reverse vaccinology approach to explore Enterococcus faecium (VRE) strains for identification of novel multi-epitopes vaccine candidate	4
Patients with moderate to severe COVID-19 have an impaired cytokine response with an exhausted and senescent immune phenotype	4
Regulatory tumor-infiltrating lymphocytes prevail in endometrial tumors with low vascular survival ability	4
CD14 regulates the metabolomic profiles of distinct macrophage subsets under steady and activated states	4
IL-37 alleviates TNF-α-induced pyroptosis of rheumatoid arthritis fibroblast-like synoviocytes by inhibiting the NF-κB/GSDMD signaling pathway	4
Diagnostic biomarkers of dilated cardiomyopathy	4
Adenosine receptor activation promotes macrophage class switching from LPS-induced acute inflammatory M1 to anti-inflammatory M2 phenotype	4
TLR2 and TLR4 mRNA expression levels in liver transplant patients with acute rejection	4
Taurochenodeoxycholic acid reduces astrocytic neuroinflammation and alleviates experimental autoimmune encephalomyelitis in mice	4
Role of FSCN1 in the tumor microenvironment of lung squamous cell carcinoma	4
Immunomodulatory role of Th17 pathway in experimental visceral leishmaniasis	4
Physiological estrogen levels are dispensable for the sex difference in immune responses during allergen-induced airway inflammation	4
IL-27 regulates autophagy in rheumatoid arthritis fibroblast-like synoviocytes via STAT3 signaling	4
Is a negative correlation between sTNFR1 and TNF in patients with chronic Chagas disease the key to clinical progression?	4
PD-L1 and PD-L2 immune checkpoint protein induction by type III interferon in non-small cell lung cancer cells	4
An optimized method to visualize the goblet cell-associated antigen passages and identify goblet cells in the intestine, conjunctiva, and airway	4
Different roles of intracellular and extracellular reactive oxygen species of neutrophils in type 2 diabetic mice with invasive aspergillosis	4
Monitoring of autoantibodies against CYP4Z1 in patients with colon, ovarian, or prostate cancer	4
Selective HSP90β inhibition results in TNF and TRAIL mediated HIF1α degradation	4
Selected factors of the innate immunity in Polish patients suffering from pulmonary tuberculosis	4
Association between severe diabetic retinopathy and lectin pathway proteins – an 18-year follow-up study with newly diagnosed type 1 diabetes patients	3
Properdin produced by dendritic cells contributes to the activation of T cells	3
Minimal structure of IRAK-1 to induce degradation of TRAF6	3
Immunological screening of Lassa Virus among Health workers and Contacts of patients of Lassa fever in Ondo State	3
Formyl peptide receptor 2 (FPR2) antagonism is a potential target for the prevention of Brucella abortus 544 infection	3
Development of a novel trivalent invasive non-typhoidal Salmonella outer membrane vesicles based vaccine against salmonellosis and fowl typhoid in chickens	3
A multilocus genetic study evidences the association of autoimmune-related genes with Psoriatic Arthritis in Italian patients	3
Successful perioperative management of three patients with hereditary angioedema without C1 esterase inhibitor therapy: A developing country perspective	3

Down-regulation of MLLT1 super elongation complex subunit impairs the anti-tumor activity of natural killer cells in esophageal cancer	3
Flow cytometry profiling of cellular immune response in COVID-19 infected, recovered and vaccinated individuals	3
Abatement of cyclophosphamide-induced splenic immunosuppressive indoleamine 2, 3-dioxygenase and altered hematological indices in Wister rats by dietary quercetin	3
A combined ratio change of inflammatory biomarkers at 72 h could predict the severity and prognosis of sepsis from pulmonary infections	3
In vitro characterization of granulocyte-colony stimulating factor (G-CSF) production by dendritic cells and macrophages during Streptococcus suis infection	3
The TGFB1 -509C/T polymorphism and elevated TGF-β1 levels are associated with chronic hepatitis C and cirrhosis	3
Streptococcal arginine deiminase regulates endothelial inflammation, mTOR pathway and autophagy	3
The role of dendritic cells in neuroblastoma: Implications for immunotherapy	3
Protective effect of two new nanovaccines against Pseudomonas aeruginosa based on LPS and OPS: A comparison study	3
In vitro immunobiological assays of methotrexate-stearic acid conjugate in human PBMCs	3
MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels	3
Highlighting the versatility of the citrullination process	3
Anti-neutrophil antibodies (anti-MPO-ANCAs) are associated with poor prognosis in breast cancer patients	3
Exploring the relationship between pyroptosis, infiltrating immune cells and Kawasaki disease with resistance to intravenous immunoglobulin (IVIG) via bioinformatic analysis	3
MerTK negatively regulates Staphylococcus aureus induced inflammatory response via SOCS1/SOCS3 and Mal	3
Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages	3
IL-6, IL-10, sFas, granulysin and indicators of intestinal permeability as early biomarkers for a fatal outcome in COVID-19	3
Peripheral changes in T cells predict efficacy of anti-PD-1 immunotherapy in non-small cell lung cancer	3
The establishment of humanized IL-4/IL-4RA mouse model by gene editing and efficacy evaluation	3
PAC1 deficiency attenuates progression of atherosclerosis in ApoE deficient mice under cholesterol-enriched diet	3
An association of iNKT+/CD3+/CD161+ lymphocytes in ovarian cancer tissue with CA125 serum concentration	3
Induced antigen-binding polyreactivity in human serum IgA	3
Leucine rich repeats and calponin homology domain containing 1 inhibits NK-92 cell cytotoxicity through attenuating Src signaling	3
In-silico immunoinformatic analysis of SARS-CoV-2 virus for the development of putative vaccine construct	3
Interleukin 17, the double-edged sword in atherosclerosis	3
Human B cells infected by Trypanosoma cruzi undergo F-actin disruption and cell death via caspase-7 activation and cleavage of phospholipase Cγ1	3
Deregulated phenotype of autoreactive Th17 and Treg clone cells in pemphigus vulgaris after in-vitro treatment with desmoglein antigen (Dsg-3)	3
Myeloid arginase-1 controls excessive inflammation and modulates T cell responses in Pseudomonas aeruginosa pneumonia	3
Non-coding RNA network associated with obesity and rheumatoid arthritis	3
Innate and adaptive immune responses against Influenza A Virus: Immune evasion and vaccination strategies	3
Omenn syndrome caused by a novel homozygous mutation in recombination activating gene 1	3
Down-regulation of miR-18b-5p protects against splenic hemorrhagic shock by directly targeting HIF-1α/iNOS pathway	3
The role of IL-17A/IL-17RA and lung injuries in children with lethal non-pandemic acute viral pneumonia	3