Immunobiology

Article	Citations
Novel evaluation indicators of MOG35∼55 induced experimental autoimmune encephalomyelitis in C57BL/6J mice	55
Expression profile of MUC1 protein in Pigeon allergens positive asthmatic	39
Opportunistic pneumonia caused by E. cuniculi in mice immunosuppressed with cyclophosphamide	33
Maternal stress increases risk of allergic lung inflammation in adult mice	31
130 Low Gene Copy Numbers (GCN) of complement C4 and C4A deficiency are highly significant genetic risk factors for idiopathic inflammatory myopathies and its major subgroups	29
230 Interaction of factor H and factor H-related proteins with S and N proteins of SARS-CoV-2	27
242 Does C1q modulate myelin sheath development in zebrafish?	24
147 Antibodies against Streptococcus pneumoniae pneumolysin correlate with modified HDL levels and complement activation markers in peripheral arterial disease patients	24
164 Role of nutraceuticals in ameliorating inflammation in Alzheimer[StQuote]s disease	24
Ubiquitin-specific protease 34 in macrophages limits CD8 T cell-mediated onset of vitiligo in mice	23
LncRNA OGFRP1 promotes angiogenesis and epithelial-mesenchymal transition in colorectal cancer cells through miR-423-5p/CTCF axis	22
Reduced susceptibility to COVID-19 associated with ABO blood group and pre-existing anti-A and anti-B antibodies	22
CARD11 dominant negative mutation leads to altered human Natural Killer cell homeostasis	22
Decreased number of myeloid-derived suppressor cells in the placental trophoblast of gestational diabetes mellitus. Possible role of leptin	21
Antipyretic and anti-inflammatory effects of inosine, an active component of Kangfuxin	20
The predictive value of miR-377 and phospholipase A2 in the early diagnosis of diabetic kidney disease and their relationship with inflammatory factors	19
221 SYNERGY-1: A Phase 1, first-in-human, randomized, double-blind, placebo-controlled safety, tolerability, immunogenicity, PK and PD study of KP104 in escalating single and multiple doses	17
NK-92 cells change their phenotype and function when cocultured with IL-15, IL-18 and trophoblast cells	17
44 Bi-specific antibodies targeting C1q and a tumor antigen activate the complement system independent of C1q-Fc interactions	16
51 Activation of complement in a mouse model of severe COVID-19	16
243 Anti-GPC1 IgM activating the complement system is an effective treatment in a pancreatic ductal adenocarcinoma mouse model	15
134 Mesangial cells derived complement factor H inhibits complement activation and inflammation in IgA Nephropathy	15
Genome interaction of the virus and the host genes and non-coding RNAs in SARS-CoV-2 infection	15
36 Phase 1 clinical data for single-dose subcutaneous injection of RLYB116, a C5 blocking Affibody® molecule linked to an Albumod® albumin binding domain	15
Editorial Board	15

Clinical and immunological characteristics of sarcomas patients with clonogenic tumors	14
The TLR4/NF-κB signaling pathway-mediated type 2 skewing of T helper cell in cough variant asthma was counteracted by ethanol extract of Anacyclus pyrethrum root	14
Management of pregnancy in hereditary angioedema in a resource constrained setting: Our experience at Chandigarh, North India	14
Monocyte-derived immature dendritic cells negatively regulate hepatic stellate cells in vitro by secreting IL-10	14
Baculovirus-mediated expression of a Helicobacter pylori protein-based multiepitope hybrid gene induces a potent B cell response in mice	14
28 C1q binding and complement activation by the IgM Fc-core domain	13
116 Differential complement iC3b levels in baseline plasma of individuals at clinical high risk for psychosis	13
143 A targeted binding and activation of native C3 without proteolytic cleavage induced by contact with biosurfaces	13
125 Elevated expression of complement factor I in lung cancer cells associates with shorter survival – Potentially via non-canonical mechanism	13
Study of some immunological signatures and their association with COVID-19 in a sample of recovered Iraqi patients	13
168 Placenta specific complement activation in mice produces preeclampsia phenotype and adversely affects fetal liver function	12
APOE Drives Glioma Progression by Modulating CCL5/CCR5 Signaling in the Tumor Microenvironment and Inducing M2 Macrophage Polarization	12
157 From parasite to therapeutic: Expression, functional characterization, and therapeutic potential of the leech-derived complement inhibitor gigastasin	12
202 Development of ex-vivo models to study complement activation in bio-incompatibility reactions induced by extracorporeal devices	12
204 Novel functions of complement factor H in macrophages	12
Activation of the cGAS-STING pathway by viral dsDNA leading to M1 polarization of macrophages mediates antiviral activity against hepatitis B virus	11
Regulatory tumor-infiltrating lymphocytes prevail in endometrial tumors with low vascular survival ability	11
Identification of a novel role for the immunomodulator ILRUN in the development of several T cell subsets in mice	10
Down-regulation of miR-18b-5p protects against splenic hemorrhagic shock by directly targeting HIF-1α/iNOS pathway	10
Immunomodulation in the intestinal mucosa of mice supplemented with Lactobacillus rhamnosus (ATCC 7469) and infected with Toxocara canis	10
Changes in extracellular cytokines in predicting disease severity and final clinical outcome of patients with blunt chest trauma	10
A small fragment of factor B as a potential inhibitor of complement alternative pathway activity	10
Exploring liquid-liquid phase separation-related diagnostic biomarkers in osteoarthritis based on machine learning algorithms and experiment	10
Silencing LINC01234 represses pancreatic cancer progression by inhibiting the malignant phenotypes of pancreatic cancer cells	9
Biomarker identification for rheumatoid arthritis with inadequate response to DMARD and TNF therapies using multidimensional analyses	9
56 Complement biomarkers reflect the pathological status of neuromyelitis optica spectrum disorders	9
Influence of NOD-like receptor 2 gene polymorphisms on muramyl dipeptide induced pro-inflammatory response in patients with active pulmonary tuberculosis and household contacts	9
Identification and validation of a novel NK cells-related signature to predict prognosis and immune microenvironment in LUAD	9
Optimized outcome prediction of oncogenetic mutations in non-early T-cell precursor acute lymphoblastic leukemia	9
Qufeng epimedium decoction alleviates rheumatoid arthritis through CYLD-antagonized NF-kB activation by deubiquitinating Sirt1	9
25 A phase 2/3 study evaluating the efficacy and safety of pozelimab in patients with CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and protein-losing enteropathy (CHAPLE	9
Paraquat induces microglial cause early neuronal synaptic deficits through activation of the classical complement cascade response	9
A retrospective observational study to estimate the risk of HLA alloimmunization with blood transfusion: Can the risk be reduced by leucodepletion?	9
Single-cell RNA and TCR repertoire analysis identify markers of virus-specific T cells	8
67 Strategic targeting of complement to regulate neuroinflammation and synapse pruning in Alzheimer’s disease	8
50 Protective role of complement factor H against the development of preeclampsia	8
C2 by-pass: Cross-talk between the complement classical and alternative pathways	8
Tumor-infiltrating lymphocytes, PD-L1, and MMR-deficiency combined characterization may identify subgroups of rectal cancer patients who would benefit from immunotherapy	8
219 Therapy induced senescence in cancer cell lines affects complement activation and complement regulatory proteins expression	8
Inactivation of the Complement Lectin Pathway by Candida tropicalis Secreted Aspartyl Protease-1	8
88 Identification and characterization of a novel complement factor I-binding protein in Pasteurella multocida	8
Identification and validation of ferroptosis-related prognostic risk model and immune landscape in hepatocellular carcinoma	8
66 Tumor-derived complement is required for tumor growth in syngeneic murine STK11-mutant lung adenocarcinoma	7
Comparison of urine and serum IgG detection ELISA for tegumentary leishmaniasis diagnosis and prognosis	7
42 APPARENT: A multicenter, randomized, double-blind, placebo-controlled Phase 3 study to assess the efficacy and safety of iptacopan in idiopathic (primary) immune complex-mediated membranoproliferat	7
Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway	7
High expression of NF-κB inducing kinase in the bulge region of hair follicle induces tumor	7
103 C3d-Directed Factor H Delivers Potent and Durable Local Complement Inhibition, Disease-Modifying Efficacy, and Decreased Renal-Derived C5b-9 Without Inhibiting Systemic Complement	7
166 The complement system is dysregulated in long covid patients	7
Association between peripheral blood WBCs C3aR mRNA level and plasma C3a, C3aR, IL-1β concentrations and acute exacerbation of chronic obstructive pulmonary disease	7

Single-cell transcriptome analysis of macrophage subpopulations contributing to chemotherapy resistance in ovarian cancer	7
174 Factor H-related dimer equilibrium and kinetics revealed through novel specific ELISAs	7
TNFSF4 is a risk factor for rheumatoid arthritis but not for primary Sjögren's syndrome in the Mexican population	7
190 The activation of the lectin pathway serine proteases by fibrin and it’s subsequent effect in clot formation	7
ML365 inhibits lipopolysaccharide-induced inflammatory responses via the NF-κB signaling pathway	6
The phenotype and related gene expressions of macrophages in adipose tissue of T2D mice following MSCs infusion	6
Precolostral antibody reactivity against Histophilus somni conserved proteins and Escherichia coli whole cells in stillborn and live calves	6
Harnessing miR-16-5p-Loaded Exosomes from Adipose-Derived Stem Cells to Restore Immune Homeostasis in SLE Patients	6
LncRNA FENDRR/ miR-424-5p serves as a diagnostic biomarker for sepsis and its predictive value for clinical outcomes	6
Vitexin along with verapamil downregulates efflux pump P-glycoprotein in macrophages and potentiate M1 to M2 switching via TLR4-NF-κB-TNFR2 pathway in lipopolysaccharide treated mice	6
Omicron variant infection and the associated immunological scenario	6
Regulation of FOXM1 by HDAC3 Inhibition Ameliorates Macrophage Endoplasmic Reticulum stress and Apoptosis in Mycobacterium tuberculosis Infection	6
V-set domain containing T-cell activation inhibitor-1 (VTCN1): A potential target for the treatment of autoimmune diseases	6
Higher proinflammatory responses possibly contributing to suppressed cytotoxicity in patients with COVID-19 associated mucormycosis	6
Polymorphisms in Toll-like receptors genes changes the host’s immune response and is associated with cervical cancer	6
Targeting C5a is beneficial in critically ill COVID-19 patients	6
Interactions of Candida tropicalis pH-related antigen 1 with complement proteins C3, C3b, factor-H, C4BP and complement evasion	6
Lactobacillus rhamnosus reduces CD8+T cell mediated inflammation in patients with rheumatoid arthritis	6
miR-146a-5p regulates autophagy and NLRP3 inflammasome activation in epithelial barrier damage in the in vitro cell model of ulcerative colitis through the RNF8/Notch1/mTORC1 pathway	6
Development of dominant epitope-based vaccines encoding Gp63, Kmp-11 and Amastin against visceral leishmaniasis	5
Granulomatous inflammation and hypogammaglobulinemia: Clinical conundrum of familial hemophagocytic lymphohistiocytosis type 5	5
CVB3 regulates Treg cell pyroptosis through the lncRNA XIST/miR-195-5p/caspase-1 molecular axis	5
74 αβ T cells and complement meet again: TCR crosstalk with surface complement regulators	5
CCR4+ monocytic myeloid-derived suppressor cells are associated with the increased epithelial-mesenchymal transition in pancreatic adenocarcinoma patients	5
216 Association of a new variant of complement regulator FHR2 with C3 glomerulopathy	5
207 Crystal structure of the Factor H domains 8-14 in complex with the Factor H-recruiting peptide 5C6 validates the unprecedented domain arrangement in the central segment of Factor H	5
131 Dual inhibition of the complement system and toll-like receptors prevents systemic and local kidney inflammation in mice experiencing brain death	5
Immune activating and inhibiting effects of calcitriol on γδ T cells and NK cells	5
Down-regulation of MLLT1 super elongation complex subunit impairs the anti-tumor activity of natural killer cells in esophageal cancer	5
ERAP1 binds peptide C-termini of different sequences and/or lengths by a common recognition mechanism	5
227 Nomacopan as an anti-shock drug for pre-hospital treatment of traumatic hemorrhage through switching the injury phenotype to survival phenotype	5
238 Characterizations of structural and functional diversities of human complement C4A and C4B allotypes	5
Calprotectin as a novel diagnostic approach to screen male infertility risk: A pilot study	5
The role of NFAT2/miR-20a-5p signaling pathway in the regulation of CD8+ naïve T cells activation and differentiation	5
Inhibiting the alternative pathway of complement by reducing systemic complement factor B: Randomized, double-blind, placebo-controlled phase 1 studies with Sefaxersen	5
49 The binding and kinetics of normal versus pathogenic C3 convertase autoantibodies	5
178 Complement component C1q can predict patients’ response to cisplatin depending on tumour type: A step towards personalized medicine?	5
183 Exploring the role of C5aR2 in neutrophil-driven autoimmune diseases: An often overlooked player in the pathogenesis of epidermolysis bullosa acquisita	5
Editorial Board	4
23 Study of complement modulation by reactive oxygen species: Revision of existing in vitro data	4
Conversion of AML-blasts to leukemia-derived dendritic cells (DCleu) in ‘DC-culture-media’ shifts correlations of released chemokines with antileukemic T-cell reactions	4
Comparable cytokine release ex-vivo by whole blood from COVID-19 patients with and without non-invasive ventilation	4
Editorial Board	4
Limosilactobacillus fermentum modulates the gut-airway axis by improving the immune response through FOXP3 activation on combined allergic rhinitis and asthma syndrome (CARAS)	4
IL-37 alleviates TNF-α-induced pyroptosis of rheumatoid arthritis fibroblast-like synoviocytes by inhibiting the NF-κB/GSDMD signaling pathway	4
A Flow Cytometric Approach to Assess RBC-Bound IgG Antibodies in Different Age Populations	4
72 Elucidation of novel exosite interactions in the activation and control of the classical pathway of complement	4
15 Defining the impact of factor H, factor H-related 1, and factor H-related 5 on C3b deposition on mouse mesangial cells	4
Bavachin inhibits IL-4 expression by downregulating STAT6 phosphorylation and GATA-3 expression and ameliorates asthma inflammation in an animal model	4
170 Increased complement activation in recipients is associated with chronic rejection after lung transplantation	4
The involvement of oxidative stress and the TLR4/NF-κB/NLRP3 pathway in acute lung injury induced by high-altitude hypoxia	4
Impact of gold nanoparticles (AuNPs) on eosinophils isolated from male and female individuals	4
100 LPS O1-antigen-mediated complement-resistance of Klebsiella pneumoniae clinical isolates	4
Highlighting the versatility of the citrullination process	4
SIRT7 affects autophagy and activation of hepatic stellate cells by regulating the acetylation level of high mobility group protein 1	4
The oncogene ABL1 regulates the inflammatory response of innate immunity via mediating TRAF6 ubiquitination	4
Genetic regulation of iron homeostasis in sideropenic patients with mild COVID-19 disease under a new oral iron formulation: Lessons from a different perspective	4
34 Anti-tumor effect of resident macrophages bearing complement component C1q in targeted therapy with CD19- Chimeric antigen receptor (CAR)-T cell	4
Shared biomarkers of multi-tissue origin for primary Sjogren's syndrome and their importance in immune microenvironment alterations	4
Retraction notice to “Increased levels of Th17 cells are associated with non-neuronal acetylcholine in COPD patients” [Immunobiology 219(5) (2014) 392–401]	4
Prevalence of high affinity naturally occurring IgG2 antibodies against human chorionic gonadotropin and its subunits in patients with ovarian cyst	4
Identification of B cell epitopes of Per a 5 allergen using bioinformatic approach	4
Editorial Board	4
213 Complement C3 deficiency enhances the effector function of CD8+ T cells and inhibits tumour growth	4
113 Complement System and leptospirosis: Understanding the role of C3 during the renal fibrosis caused during chronic infection by pathogenic leptospires in murine experimental model	4
Targeting B7-H3 in solid tumors: Development and evaluation of novel CAR-T Cell therapy	4
Innate antiviral responses in porcine nasal mucosal explants inoculated with influenza A virus are comparable with responses in respiratory tissues after viral infection	4
Editorial Board	4
222 Complement Activation in Cytokine Storms Associated with COVID-19, Sepsis, and Chimeric Antigen Receptor (CAR)-T Therapy	4
T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1	3
Insights into IL-33 on inflammatory response during in vitro infection by Trypanosoma cruzi	3
Serological markers of rheumatoid arthritis in patients with primary biliary cholangitis and the vice versa: A Tunisian study	3
IL-27p28 specifically regulates MHC II expression in macrophages through CIITA	3
l-ficolin-MASP arm of the complement system in schizophrenia	3
Editorial Board	3
192 Molecular imaging of renal C3d deposition to monitor lupus nephritis	3
Ureaplasma urealyticum GrpE protein elicits glycolysis-mediated inflammatory responses through TLR2 in macrophages	3
Explore the mechanism of incomplete Kawasaki disease and identify a novel biomarker by weighted gene co-expression network analysis	3
IL-9 and IL-9 receptor expression in lymphocytes from bronchoalveolar lavage fluid of patients with interstitial lung disease	3
Myeloperoxidase-deficient mice exposed to Zymosan exhibit severe neutrophilia and anemia with enhanced granulopoiesis and reduced erythropoiesis, accompanied by pulmonary inflammation	3

CCR1 antagonist J-113863 corrects the imbalance of pro- and anti-inflammatory cytokines in a SJL/J mouse model of relapsing-remitting multiple sclerosis	3
Full length RAG2 expression enhances the DNA damage response in pre-B cells	3
Macrophage Migration Inhibitory Factor contributes to drive phenotypic and functional macrophages activation in response to Toxoplasma gondii infection	3
Physiological estrogen levels are dispensable for the sex difference in immune responses during allergen-induced airway inflammation	3
105 Elucidating the role of anaphylatoxins and their receptors in osteoarthritis regarding cartilage calcification	3
CD8 T lymphocytes from B-1 cell-deficient mice down-regulates fungicidal activity of macrophages challenged with E. Cuniculi	3
Editorial Board	3
Down-regulation of HLA-B-associated transcript 3 impairs the tumoricidal effect of natural killer cells through promoting the T cell immunoglobulin and mucin domain-containing-3 signaling in a mouse h	3
Involvement of Xeroderma Pigmentosum Complementation Group G (XPG) in epigenetic regulation of T-Helper (TH) cell differentiation during breast cancer	3
153 Visualizing complement activation and regulation in the tumor microenvironment	3
Irisin attenuates fine particulate matter induced acute lung injury by regulating Nod2/NF-κB signaling pathway	3
IL-27 regulates autophagy in rheumatoid arthritis fibroblast-like synoviocytes via STAT3 signaling	3
Associations of HLA-G 3’UTR polymorphisms and increased HLA-G expression with gastric cancer susceptibility and prognosis	3
80 C5b-9 and Bb factor levels as potential novel biomarkers in crescentic IgA nephropathy	3
Editorial Board	3
53 Increased infiltration of CD4+ T cell in the complement deficient lymphedema model	3
193 Iptacopan (LNP023) inhibits activity of FB mutants identified in patients with atypical hemolytic uremic syndrome (aHUS)	3
PDE4D gene variants and haplotypes are associated with asthma and atopy in Brazilian children	3
Peripheral changes in T cells predict efficacy of anti-PD-1 immunotherapy in non-small cell lung cancer	3
46 The mycobacterial strain-dependent impact of the complement system in tuberculosis	3
Butyrate directly decreases human gut lamina propria CD4 T cell function through histone deacetylase (HDAC) inhibition and GPR43 signaling	3
Omenn syndrome caused by a novel homozygous mutation in recombination activating gene 1	3
70 C5a receptor 1 controls antigen and TLR-driven T cell proliferation and differentiation by splenic conventional type 2 dendritic cells	3
Abatement of cyclophosphamide-induced splenic immunosuppressive indoleamine 2, 3-dioxygenase and altered hematological indices in Wister rats by dietary quercetin	3
The utility of inflammatory and endothelial factors in the prognosis of severe dengue	3
115 The mannose-binding lectin (MBL) in MIS-C: relationship between MBL genotype, levels, and functional activity against SARS-CoV-2	3