Immunobiology

Article	Citations
Editorial Board	52
Editorial Board	39
RNA-Seq and ATAC-Seq analyses reveal a global transcriptional and chromatin accessibility profiling of γδ T17 differentiation from mouse spleen	25
Editorial Board	25
130 Low Gene Copy Numbers (GCN) of complement C4 and C4A deficiency are highly significant genetic risk factors for idiopathic inflammatory myopathies and its major subgroups	24
164 Role of nutraceuticals in ameliorating inflammation in Alzheimer[StQuote]s disease	22
84 Inhibition of SARS-CoV-2 spike interaction with angiotensin converting enzyme-2 (ACE2) by specific antibodies is enhanced by complement, determined with a novel flow cytometry assay	22
146 A transcriptome array-based approach to link SGLT-2 and tubulointerstitial synthesis of complement C5 in IgA nephropathy	21
165 IQGAP1 deficiency promotes complement activation on podocytes: New insights into the pathogenesis of kidney complement-mediated disease	19
TLR-2 agonist Pam3CSK4 has no therapeutic effect on visceral leishmaniasis in BALB/c mice and may enhance the pathogenesis of the disease	18
Macrophages promote heat stress nephropathy in mice via the C3a-C3aR-TNF pathway	17
Characterization of the impact of immune checkpoint inhibitors on platelet activation and aggregation	17
Novel evaluation indicators of MOG35∼55 induced experimental autoimmune encephalomyelitis in C57BL/6J mice	17
Chronic NOD2 stimulation by MDP confers protection against parthanatos through M2b macrophage polarization in RAW264.7 cells	17
Granulomatous inflammation and hypogammaglobulinemia: Clinical conundrum of familial hemophagocytic lymphohistiocytosis type 5	16
Identification of a novel Immune-Related prognostic model for patients with colorectal cancer based on 3 subtypes	16
Infection by Strongyloides venezuelensis attenuates chronic colitis induced by Dextran Sodium Sulfate ingestion in BALB/c mice	15
Exposure of pregnant rats to staphylococcal enterotoxin B increases offspring splenic Treg number and function via decreasing FoxP3 methylation	15
Preferential production and secretion of the complement regulator factor H-like protein 1 (FHL-1) by human myeloid cells	14
LncRNA OGFRP1 promotes angiogenesis and epithelial-mesenchymal transition in colorectal cancer cells through miR-423-5p/CTCF axis	14
A novel peptide vaccination augments cytotoxic CD8+ T-cell responses against Mycobacterium tuberculosis HspX antigen	14
PD-L1 and PD-L2 immune checkpoint protein induction by type III interferon in non-small cell lung cancer cells	13
IgD ligation allows peritoneal cavity B cell proliferation	13
Seroprevalence and systemic immune biomarkers associated with Toxoplasma gondii infection in blood donors from Southern Brazil	13
Maternal stress increases risk of allergic lung inflammation in adult mice	13

Exploring the relationship between pyroptosis, infiltrating immune cells and Kawasaki disease with resistance to intravenous immunoglobulin (IVIG) via bioinformatic analysis	12
ELAVL1 promotes LPS-induced endothelial cells injury through modulation of cytokine storm	12
Complement activation and kidney transplantation; a complex relationship	12
Down-regulation of MLLT1 super elongation complex subunit impairs the anti-tumor activity of natural killer cells in esophageal cancer	11
Deletion of mesencephalic astrocyte-derived neurotrophic factor delays and damages the development of white pulp in spleen	11
What do we know about the antibody responses to SARS-CoV-2?	11
Alterations in Helios+ T cell subsets in peripheral blood of early-stage lung adenocarcinoma patients: Implications for early diagnosis	10
PLEKHA4 promotes glioblastoma progression through apoptosis inhibition, tumor cell migration, and macrophage infiltration	10
NK-92 cells change their phenotype and function when cocultured with IL-15, IL-18 and trophoblast cells	10
Multifocal thrombosis with peripheral gangrene in a young boy: Mycoplasma infection triggered cold agglutinin disease	10
ERAP1 binds peptide C-termini of different sequences and/or lengths by a common recognition mechanism	10
225 Single cell analysis (SCA) of PBMCs for a patient with congenital non-functional CD59	9
Expression profile of MUC1 protein in Pigeon allergens positive asthmatic	9
104 Targeting terminal pathway in brain reduces complement activation and synapse loss in a mouse model of dementia	9
The significance of antiglobulin (Coombs) test reactivity in patients with COVID-19	9
Amniotic fluid stem cell attenuated necrotizing enterocolitis progression by promoting Rspo3/AMPKα axis	9
27 Elucidating the molecular mechanisms mediating the tumor suppressive actions of complement inhibitor CSMD1 in gliomas	9
Lactobacillus delbrueckii UFV-H2b20 increases IFN-γ production and CD39+CD73+ Treg cell numbers in lungs, and protects mice against experimental allergic asthma	9
Genetic polymorphisms of rs73620203 in the transforming growth interacting factor gene associated with rheumatoid arthritis in a Chinese population	9
81 Clinical and histologic correlations in C3 glomerulopathy	8
86 Assessing Complement Factor B Function: A Comparison of Hemolytic and Immunofixation Electrophoresis-based Assays	8
147 Antibodies against Streptococcus pneumoniae pneumolysin correlate with modified HDL levels and complement activation markers in peripheral arterial disease patients	8
220 CD59-/- is protected from glucose intolerance, insulin resistance and fatty liver disease	8
93 Modeling complement activation on human glomerular microvascular endothelial cells	8
109 Investigation of complement-related integrin receptors using a screening platform and newly developed tool compounds	8
49 The binding and kinetics of normal versus pathogenic C3 convertase autoantibodies	8
170 Increased complement activation in recipients is associated with chronic rejection after lung transplantation	8
99 Targeted complement inhibition using engineered bispecific antibodies that bind local antigens and endogenous complement regulators as a novel therapeutic approach	8
232 Effect of IL-1ß and C3a on complement expression and secretion on human osteoarthritic chondrocytes	8
20 The C5aR2 pathway as a potential novel checkpoint for B cell activation and differentiation	7
74 αβ T cells and complement meet again: TCR crosstalk with surface complement regulators	7
210 Complement activation in patients with ANCA-associated vasculitis – focusing on complement activation markers in remission	7
237 Despite altered immune compartments and increased complement consumption, heterozygous C3 gain-of-function mice do not develop atypical haemolytic syndrome following exposure to various inflammato	7
242 Does C1q modulate myelin sheath development in zebrafish?	7
59 DNA-templated antibody complexes provide insights into the geometric requirements of human complement activation	7
90 Complement activation during hypoxia-reoxygenation in human kidney epithelial cells	6
123 The temporal role of complement in severe trauma and hemorrhagic shock	6
230 Interaction of factor H and factor H-related proteins with S and N proteins of SARS-CoV-2	6
41 Assessing the feasibility of genetically modified porcine red blood cells as an alternative to human red blood cells for transfusion	6
63 Heme-induced complement activation in invasive aspergillosis	6
47 Plasma factor D cross-sectionally associates with low-grade inflammation, endothelial dysfunction and cardiovascular disease, but not with intima-media thickness or ankle-brachial index: The Maastr	6
199 A role for complement in sickle cell disease	6
71 Acinetobacter baumannii clinical isolates evade complement-mediated lysis by inhibiting the complement cascade and improperly depositing MAC	6
185 CPV-104, an improved recombinant variant of human complement factor H produced in moss, is a prime candidate for clinical application in complement mediated diseases	6
33 C5 cleavage inhibition combined with C3 convertase targeting protects from disease development in a preclinical model of autoimmune skin disease	6
201 Leptospira interrogans leptolysin displays proteolytic activity against complement proteins	6
138 Escherichia coli-induced platelet aggregation in human whole blood is partly dependent on complement C3b	6
37 Intracellular complement in atypical hemolytic-uremic syndrome	6
23 Study of complement modulation by reactive oxygen species: Revision of existing in vitro data	6
171 The dominant form of the C1 inhibitor R444C variant causing type II hereditary angioedema is its covalent adduct with serum albumin explaining elevated levels	6

Toll-like receptor 2 deficiency relieves splenic immunosuppression during sepsis	5
Adenosine receptor activation promotes macrophage class switching from LPS-induced acute inflammatory M1 to anti-inflammatory M2 phenotype	5
Association of neutrophil extracellular trap levels with Raynaud’s phenomenon, glomerulonephritis and disease index score in SLE patients from Brazil	5
The involvement of oxidative stress and the TLR4/NF-κB/NLRP3 pathway in acute lung injury induced by high-altitude hypoxia	5
The safety and efficacy of tumor necrosis factor-alpha inhibitor on pregnancy outcomes in patients with unexplained recurrent miscarriage	5
Opportunistic pneumonia caused by E. cuniculi in mice immunosuppressed with cyclophosphamide	5
Reduced susceptibility to COVID-19 associated with ABO blood group and pre-existing anti-A and anti-B antibodies	5
Selective downregulation of natural killer activating receptors on NK cells and upregulation of PD-1 expression on T cells in children with severe and/or recurrent Herpes simplex virus infections	5
Apelin triggers macrophage polarization to M2 type in head and neck cancer	5
Intestinal production of secreted protein acidic and rich in cysteine (SPARC) in patients with ulcerative colitis	5
Antipyretic and anti-inflammatory effects of inosine, an active component of Kangfuxin	5
Immune activating and inhibiting effects of calcitriol on γδ T cells and NK cells	5
Bavachin inhibits IL-4 expression by downregulating STAT6 phosphorylation and GATA-3 expression and ameliorates asthma inflammation in an animal model	5
Regulatory relationship between macrophage autophagy and PVL-positive methicillin-resistant Staphylococcus aureus	5
Acquired decrease of the C3b/C4b receptor (CR1, CD35) and increased C4d deposits on erythrocytes from ICU COVID-19 patients	5
Deregulated phenotype of autoreactive Th17 and Treg clone cells in pemphigus vulgaris after in-vitro treatment with desmoglein antigen (Dsg-3)	5
CARD11 dominant negative mutation leads to altered human Natural Killer cell homeostasis	5
Transcription suppression of GABARAP mediated by lncRNA XIST-EZH2 interaction triggers caspase-11-dependent inflammatory injury in ulcerative colitis	5
LncRNA SNHG1 overexpression alleviates osteoarthritis via activating PI3K/Akt signal pathway and suppressing autophagy	5
Non-coding RNA network associated with obesity and rheumatoid arthritis	5
Induction of CIITA by IFN-γ in macrophages involves STAT1 activation by JAK and JNK	5
Immune regulations by 14-3-3: A misty terrain	5
Ubiquitin-specific protease 34 in macrophages limits CD8 T cell-mediated onset of vitiligo in mice	5
Editorial Board	4
Clinical and immunological characteristics of sarcomas patients with clonogenic tumors	4
Retraction notice to “Increased levels of Th17 cells are associated with non-neuronal acetylcholine in COPD patients” [Immunobiology 219(5) (2014) 392–401]	4
Highly dampened HIV-specific cytolytic effector T cell responses define viremic non-progression	4
Toll-like receptor upregulation in liver and peripheral blood mononuclear cells of patients with amoebic liver abscess	4
Nanoparticle-induced immune response: Health risk versus treatment opportunity?	4
Th-1, Th-2, Th-9, Th-17, Th-22 type cytokine concentrations of critical COVID-19 patients after treatment with Remdesivir	4
Editorial Board	4
Clostridium butyricum attenuates LPS-induced myocardial injury in septic mice by modulating CD4 + CD25 + FOXP3 + Treg	4
The role of NFAT2/miR-20a-5p signaling pathway in the regulation of CD8+ naïve T cells activation and differentiation	4
MiR-183-5p overexpression in bone mesenchymal stem cell-derived exosomes protects against myocardial ischemia/reperfusion injury by targeting FOXO1	4
An optimized method to visualize the goblet cell-associated antigen passages and identify goblet cells in the intestine, conjunctiva, and airway	4
Inhibiting the alternative pathway of complement by reducing systemic complement factor B: Randomized, double-blind, placebo-controlled phase 1 studies with Sefaxersen	4
Editorial Board	4
Prevalence of high affinity naturally occurring IgG2 antibodies against human chorionic gonadotropin and its subunits in patients with ovarian cyst	4
Interleukin-1beta triggers the expansion of circulating granulocytic myeloid-derived suppressor cell subset dependent on Erk1/2 activation	4
The predictive value of miR-377 and phospholipase A2 in the early diagnosis of diabetic kidney disease and their relationship with inflammatory factors	4
STING modulates HBV-related acute-on-chronic liver failure by mediating autophagy and macrophage polarization	4
Editorial Board	4
140 A novel selective leukocyte depletion human whole blood model reveals the specific roles of monocytes and granulocytes in the cytokine response to Escherichia coli	3
6 Development of a C3 humanized rat as a new model for evaluating novel C3 inhibitors	3
52 Human factor H and properdin modulate SARS-CoV-2 infection in a complement-independent manner	3
134 Mesangial cells derived complement factor H inhibits complement activation and inflammation in IgA Nephropathy	3
181 Complement C7 and clusterin form a stable complex in circulation	3
Arginase is involved in cervical lesions progression and severity	3
44 Bi-specific antibodies targeting C1q and a tumor antigen activate the complement system independent of C1q-Fc interactions	3
Limosilactobacillus fermentum modulates the gut-airway axis by improving the immune response through FOXP3 activation on combined allergic rhinitis and asthma syndrome (CARAS)	3
Intrinsic chemical reactivity of activated human complement component C3: A historical glimpse into research during 1979–1980 on the covalent binding properties of C3, C4 and alpha-2 macroglobulin	3
Comparable cytokine release ex-vivo by whole blood from COVID-19 patients with and without non-invasive ventilation	3
TCR-signals downstream adversely correlate with the survival signals of memory CD8+ T cells under homeostasis	3
Interleukin 17, the double-edged sword in atherosclerosis	3
114 Complement protein autoantibodies and increased Factor H related protein four levels may contribute to pathogenesis in IgA nephropathy	3
72 Elucidation of novel exosite interactions in the activation and control of the classical pathway of complement	3
132 Multiple pregnancy can induce preeclampsia-like changes in complement factor H-point mutation mice	3
55 Association between autoantibodies and complement activation in systemic lupus erythematosus	3
Highlighting the versatility of the citrullination process	3
175 Transposon mutagenesis: A molecular switch in Acinetobacter baumannii for rapid adaptation to bacteriophages and the complement system	3
Genetic regulation of iron homeostasis in sideropenic patients with mild COVID-19 disease under a new oral iron formulation: Lessons from a different perspective	3
51 Activation of complement in a mouse model of severe COVID-19	3
Conversion of AML-blasts to leukemia-derived dendritic cells (DCleu) in ‘DC-culture-media’ shifts correlations of released chemokines with antileukemic T-cell reactions	3
Chlorella vulgaris extract and Imiquimod as new therapeutic targets for leishmaniasis: An immunological approach	3
Identification of B cell epitopes of Per a 5 allergen using bioinformatic approach	3
dl-THP recovered the decreased NKp44 expression level on CD56dim CD16+ natural killer cells partially in choriocarcinoma microenvironment	3
Diagnostic biomarkers of dilated cardiomyopathy	3
221 SYNERGY-1: A Phase 1, first-in-human, randomized, double-blind, placebo-controlled safety, tolerability, immunogenicity, PK and PD study of KP104 in escalating single and multiple doses	3
94 Citrullination of C1-inhibitor as a mechanism of impaired complement inhibition in rheumatoid arthritis	3
15 Defining the impact of factor H, factor H-related 1, and factor H-related 5 on C3b deposition on mouse mesangial cells	3
150 Association between loss of immune checkpoint programmed cell death protein 1 and local synthesis of complement factor B in active ANCA-associated renal vasculitis	3
Editorial Board	3
91 Complement genetics: implementation of a custom made panel for genetic testing of complement-associated kidney patients	3
Management of pregnancy in hereditary angioedema in a resource constrained setting: Our experience at Chandigarh, North India	3
206 Expression of complement proteins by M1 and M2 macrophages: Complement factor B induces inflammatory macrophage phenotype	3
Monocyte-derived immature dendritic cells negatively regulate hepatic stellate cells in vitro by secreting IL-10	3
Alteration of PBMC transcriptome profile after interaction with multipotent mesenchymal stromal cells under “physiological” hypoxia	3
Baculovirus-mediated expression of a Helicobacter pylori protein-based multiepitope hybrid gene induces a potent B cell response in mice	3
RvD1 treatment during primary infection modulates memory response increasing viral load during respiratory viral reinfection	3
36 Phase 1 clinical data for single-dose subcutaneous injection of RLYB116, a C5 blocking Affibody® molecule linked to an Albumod® albumin binding domain	2

Human bone marrow mesenchymal stem cells-derived exosomes protect against nerve injury via regulating immune microenvironment in neonatal hypoxic-ischemic brain damage model	2
TLR4/TNFR1 blockade suppresses STAT1/STAT3 expression and increases SOCS3 expression in modulation of LPS-induced macrophage responses	2
Proportion of B cell subsets and Nrf2 mediated redox regulation in systemic lupus erythematosus patients	2
The oncogene ABL1 regulates the inflammatory response of innate immunity via mediating TRAF6 ubiquitination	2
Effects of TNF-α on autophagy of rheumatoid arthritis fibroblast-like synoviocytes and regulation of the NF-κB signaling pathway	2
Changes in extracellular cytokines in predicting disease severity and final clinical outcome of patients with blunt chest trauma	2
Deciphering the balance of IL-6/IL-10 cytokines in severe to critical COVID-19 patients	2
Immune induction by adjuvanted Leishmania donovani vaccines against the visceral leishmaniasis in BALB/c mice	2
34 Anti-tumor effect of resident macrophages bearing complement component C1q in targeted therapy with CD19- Chimeric antigen receptor (CAR)-T cell	2
PSMC2 promotes glioma progression by regulating immune microenvironment and PI3K/AKT/mTOR pathway	2
Involvement of CacyBP/SIP in differentiation and the immune response of HaCaT keratinocytes	2
Effects of combination of Cryptococcus gattii and IFN-γ, IL-4 or IL-27 on human bronchial epithelial cells	2
Genome interaction of the virus and the host genes and non-coding RNAs in SARS-CoV-2 infection	2
87 Activation of complement pathways and formation of membrane attack complex contribute to the development of severe COVID-19	2
SIRT7 affects autophagy and activation of hepatic stellate cells by regulating the acetylation level of high mobility group protein 1	2
151 Complement system remains unaltered in an acute schizophrenia	2
203 Annexin A2: A positive regulator of the alternative complement pathway in the kidney	2
Immunogenic efficacy of DNA and protein-based vaccine from a chimeric gene consisting OmpW, TcpA and CtxB, of Vibrio cholerae	2
76 C1q-IgM interaction studies with recombinant globular C1q variants	2
Propionate induces cross-tolerance to TLR1/2 and TLR4 agonists in an IFIT-dependent manner	2
Shared biomarkers of multi-tissue origin for primary Sjogren's syndrome and their importance in immune microenvironment alterations	2
Why blood group A individuals are at risk whereas blood group O individuals are protected from SARS-CoV-2 (COVID-19) infection: A hypothesis regarding how the virus invades the human body via ABO(H) b	2
Editorial Board	2
Immunoinformatics approach for a novel multi-epitope subunit vaccine design against various subtypes of Influenza A virus	2
A small fragment of factor B as a potential inhibitor of complement alternative pathway activity	2
CircEXOC5 promotes ferroptosis by enhancing ACSL4 mRNA stability via binding to PTBP1 in sepsis-induced acute lung injury	2
13 Differential contributions of C5b-9 and C5a/C5aR pathways to microvascular and macrovascular thrombosis in complement-mediated thrombotic microangiopathy patients	2
A multilocus genetic study evidences the association of autoimmune-related genes with Psoriatic Arthritis in Italian patients	2
Mitochondrial activity related genes of mast cells identify poor prognosis and metastasis of ovarian cancer	2
Alterations in the immune landscape characterized by inflammatory activation and immune escape within 12 h after trauma	2
M2-like macrophage-derived exosomes inhibit osteoclastogenesis via releasing miR-1227-5p	2
245 Sez6L2 is a brain-resident complement inhibitor that is necessary for proper brain development	2
243 Anti-GPC1 IgM activating the complement system is an effective treatment in a pancreatic ductal adenocarcinoma mouse model	2
Impact of gold nanoparticles (AuNPs) on eosinophils isolated from male and female individuals	2
222 Complement Activation in Cytokine Storms Associated with COVID-19, Sepsis, and Chimeric Antigen Receptor (CAR)-T Therapy	2
Development of a novel trivalent invasive non-typhoidal Salmonella outer membrane vesicles based vaccine against salmonellosis and fowl typhoid in chickens	2
29 Humoral innate immunity and acute phase proteins in COVID-19	2
Downregulating LKB1 in bone marrow mesenchymal stem cells could inhibit CD4+ T cell proliferation via the PD-1/PD-L1 signaling pathway	2
Identification of RNMT as an immunotherapeutic and prognostic biomarker: From pan-cancer analysis to lung squamous cell carcinoma validation	2
AURKA, as a potential prognostic biomarker, regulates autophagy and immune infiltration in nasopharyngeal carcinoma	2
Immunological screening of Lassa Virus among Health workers and Contacts of patients of Lassa fever in Ondo State	2
The TLR4/NF-κB signaling pathway-mediated type 2 skewing of T helper cell in cough variant asthma was counteracted by ethanol extract of Anacyclus pyrethrum root	2
Is a negative correlation between sTNFR1 and TNF in patients with chronic Chagas disease the key to clinical progression?	2
39 Humoral complementomics – Exploration of non-invasive complement biomarkers as predictors of renal cancer progression	2
14 Functional activity of CD35 (Complement Receptor 1; CR1) in the conversion of complement fragment iC3b to C3dg	2
Innate antiviral responses in porcine nasal mucosal explants inoculated with influenza A virus are comparable with responses in respiratory tissues after viral infection	2
64 Loss of the complement regulator CD55 alters marginal zone B cell homeostasis	2
Editorial Board	2
188 Vemircopan (ALXN2050) monotherapy in paroxysmal nocturnal hemoglobinuria: Interim data from a phase 2 open-label proof-of-concept study	2
NOD-like receptor family pyrin domain containing 3 (rs10754558) gene polymorphism in chronic spontaneous urticaria: A pilot case-control study	2
159 Functional characterization of two novel Complement Factor B variants in patients with primary Immune-Complex-mediated MPGN	2
205 The complex role of complement in hepatocellular carcinoma	2
IL-37 alleviates TNF-α-induced pyroptosis of rheumatoid arthritis fibroblast-like synoviocytes by inhibiting the NF-κB/GSDMD signaling pathway	2