Immunobiology

Article	Citations
Endothelial injury and thrombotic microangiopathy in COVID-19: Treatment with the lectin-pathway inhibitor narsoplimab	117
Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies	62
The role of dectin-1 in health and disease	52
Butyrate directly decreases human gut lamina propria CD4 T cell function through histone deacetylase (HDAC) inhibition and GPR43 signaling	39
SARS-CoV-2 attachment to host cells is possibly mediated via RGD-integrin interaction in a calcium-dependent manner and suggests pulmonary EDTA chelation therapy as a novel treatment for COVID 19	35
Advances in immunotherapy for the treatment of spinal cord injury	25
Regulatory role of Apelin-13-mediated PI3K/AKT signaling pathway in the glucose and lipid metabolism of mouse with gestational diabetes mellitus	25
What do we know about the antibody responses to SARS-CoV-2?	25
Why blood group A individuals are at risk whereas blood group O individuals are protected from SARS-CoV-2 (COVID-19) infection: A hypothesis regarding how the virus invades the human body via ABO(H) b	24
Nanoparticle-induced immune response: Health risk versus treatment opportunity?	22
Immunoinformatics approach for a novel multi-epitope subunit vaccine design against various subtypes of Influenza A virus	21
CCR2 and DPP9 expression in the peripheral blood of COVID-19 patients: Influences of the disease severity and gender	19
Roles of protein ubiquitination in inflammatory bowel disease	19
MiR-183-5p overexpression in bone mesenchymal stem cell-derived exosomes protects against myocardial ischemia/reperfusion injury by targeting FOXO1	19
A review on structural, non-structural, and accessory proteins of SARS-CoV-2: Highlighting drug target sites	18
BCG immunomodulation: From the ‘hygiene hypothesis’ to COVID-19	17
Complement and COVID-19: Three years on, what we know, what we don't know, and what we ought to know	17
Effects of TNF-α on autophagy of rheumatoid arthritis fibroblast-like synoviocytes and regulation of the NF-κB signaling pathway	17
MBL deficiency-causing B allele (rs1800450) as a risk factor for severe COVID-19	17
Induction of CIITA by IFN-γ in macrophages involves STAT1 activation by JAK and JNK	16
The PE-PPE Family of Mycobacterium tuberculosis: Proteins in Disguise	16
Human bone marrow mesenchymal stem cells-derived exosomes protect against nerve injury via regulating immune microenvironment in neonatal hypoxic-ischemic brain damage model	16
Acquired decrease of the C3b/C4b receptor (CR1, CD35) and increased C4d deposits on erythrocytes from ICU COVID-19 patients	15
A method to differentiate chicken monocytes into macrophages with proinflammatory properties	15
Deciphering the balance of IL-6/IL-10 cytokines in severe to critical COVID-19 patients	15

Antigenic sites in SARS-CoV-2 spike RBD show molecular similarity with pathogenic antigenic determinants and harbors peptides for vaccine development	14
Omicron variant infection and the associated immunological scenario	14
LncRNA LINC00184 promotes docetaxel resistance and immune escape via miR-105-5p/PD-L1 axis in prostate cancer	14
Immune induction by adjuvanted Leishmania donovani vaccines against the visceral leishmaniasis in BALB/c mice	13
Bacterial lipoproteins in sepsis	13
CircEXOC5 promotes ferroptosis by enhancing ACSL4 mRNA stability via binding to PTBP1 in sepsis-induced acute lung injury	13
Genome interaction of the virus and the host genes and non-coding RNAs in SARS-CoV-2 infection	12
The role of CD68+ and CD163+ macrophages in immunopathogenesis of oral lichen planus and oral lichenoid lesions	11
PM2.5 induced lung injury through upregulating ROS-dependent NLRP3 Inflammasome-Mediated Pyroptosis	11
Low molecular weight cytotoxic components (DAMPs) form the post-COVID-19 syndrome	11
α9α10 nicotinic acetylcholine receptors regulate murine bone marrow granulocyte functions	11
V-set domain containing T-cell activation inhibitor-1 (VTCN1): A potential target for the treatment of autoimmune diseases	11
PAF-R on activated T cells: Role in the IL-23/Th17 pathway and relevance to multiple sclerosis	10
Long non-coding RNA RP11-490M8.1 inhibits lipopolysaccharide-induced pyroptosis of human umbilical vein endothelial cells via the TLR4/NF-κB pathway	10
Pan genome based reverse vaccinology approach to explore Enterococcus faecium (VRE) strains for identification of novel multi-epitopes vaccine candidate	10
Leukemia derived dendritic cell (DCleu) mediated immune response goes along with reduced (leukemia-specific) regulatory T-cells	10
Polymorphisms in Toll-like receptors genes changes the host’s immune response and is associated with cervical cancer	10
Association of interleukin-17 gene polymorphisms with the onset of Rheumatoid Arthritis	10
Benznidazole: Hero or villain of cellular immune response in chronic Chagas disease patients?	10
Upregulation of leukemia-induced non-coding activator RNA (LUNAR1) predicts poor outcome in pediatric T-acute lymphoblastic leukemia	9
Immunomodulatory role of Th17 pathway in experimental visceral leishmaniasis	9
Adenosine receptor activation promotes macrophage class switching from LPS-induced acute inflammatory M1 to anti-inflammatory M2 phenotype	9
Taurochenodeoxycholic acid reduces astrocytic neuroinflammation and alleviates experimental autoimmune encephalomyelitis in mice	9
Effects of total glucosides of paeony on acute renal injury following ischemia–reperfusion via the lncRNA HCG18/miR-16-5p/Bcl-2 axis	9
Lactobacillus delbrueckii UFV-H2b20 increases IFN-γ production and CD39+CD73+ Treg cell numbers in lungs, and protects mice against experimental allergic asthma	9
Preclinical characterization of a Fab-like CD3/CLDN18.2 XFab® bispecific antibody against solid tumors	9
Monophosphoryl lipid A directly regulates Th1 cytokine production in human CD4+ T-cells through Toll-like receptor 2 and 4	9
IL-37 alleviates TNF-α-induced pyroptosis of rheumatoid arthritis fibroblast-like synoviocytes by inhibiting the NF-κB/GSDMD signaling pathway	9
Peripheral changes in T cells predict efficacy of anti-PD-1 immunotherapy in non-small cell lung cancer	8
The MHC-II antigen presentation machinery and B7 checkpoint ligands display distinctive patterns correlated with acute myeloid leukaemias blast cells HLA-DR expression	8
Bavachin inhibits IL-4 expression by downregulating STAT6 phosphorylation and GATA-3 expression and ameliorates asthma inflammation in an animal model	8
Immune response modulation by allergen loaded into mesenchymal stem cell-derived exosomes as an effective carrier through sublingual immunotherapy	8
Complement factor I: Regulatory nexus, driver of immunopathology, and therapeutic	8
CCR1 antagonist J-113863 corrects the imbalance of pro- and anti-inflammatory cytokines in a SJL/J mouse model of relapsing-remitting multiple sclerosis	8
Selective downregulation of natural killer activating receptors on NK cells and upregulation of PD-1 expression on T cells in children with severe and/or recurrent Herpes simplex virus infections	8
NK-92 cells change their phenotype and function when cocultured with IL-15, IL-18 and trophoblast cells	8
Embryonic stem cells-derived exosomes enhance retrodifferentiation of retinal Müller cells by delivering BDNF protein to activate Wnt pathway	8
Involvement of Xeroderma Pigmentosum Complementation Group G (XPG) in epigenetic regulation of T-Helper (TH) cell differentiation during breast cancer	8
Immunogenic efficacy of DNA and protein-based vaccine from a chimeric gene consisting OmpW, TcpA and CtxB, of Vibrio cholerae	8
Deregulated phenotype of autoreactive Th17 and Treg clone cells in pemphigus vulgaris after in-vitro treatment with desmoglein antigen (Dsg-3)	8
STING mediates SU5416/hypoxia-induced pulmonary arterial hypertension in rats by regulating macrophage NLRP3 inflammasome activation	8
The Nurr7 agonist Cytosporone B differentially regulates inflammatory responses in human polarized macrophages	7
Cytotoxic activity of human dendritic cells induces RIPK1-dependent cell death	7
Innate antiviral responses in porcine nasal mucosal explants inoculated with influenza A virus are comparable with responses in respiratory tissues after viral infection	7
IL-33 synergistically promotes the proliferation of lung cancer cells in vitro by inducing antibacterial peptide LL-37 and proinflammatory cytokines in macrophages	7
Physiological estrogen levels are dispensable for the sex difference in immune responses during allergen-induced airway inflammation	7
Interleukin-1beta triggers the expansion of circulating granulocytic myeloid-derived suppressor cell subset dependent on Erk1/2 activation	7
Effect of pathogenic crystals on the production of pro- and anti-inflammatory cytokines by different leukocyte populations	7
An eosinophil-Sos1-RAS axis licenses corticosteroid resistance in patients with allergic rhinitis	7
PPE2 protein of Mycobacterium tuberculosis affects myeloid hematopoiesis in mice	7

Intestinal production of secreted protein acidic and rich in cysteine (SPARC) in patients with ulcerative colitis	7
The interplay of interleukin-17A and breast cancer tumor microenvironment as a novel immunotherapeutic approach to increase tumor immunogenicity	6
Selective HSP90β inhibition results in TNF and TRAIL mediated HIF1α degradation	6
CD14 regulates the metabolomic profiles of distinct macrophage subsets under steady and activated states	6
Myeloid arginase-1 controls excessive inflammation and modulates T cell responses in Pseudomonas aeruginosa pneumonia	6
IL-27 regulates IL-4-induced chemokine production in human bronchial epithelial cells	6
Role of FSCN1 in the tumor microenvironment of lung squamous cell carcinoma	6
Complement and coagulation crosstalk – Factor H in the spotlight	6
Macrophage Migration Inhibitory Factor contributes to drive phenotypic and functional macrophages activation in response to Toxoplasma gondii infection	6
LncRNA OGFRP1 promotes angiogenesis and epithelial-mesenchymal transition in colorectal cancer cells through miR-423-5p/CTCF axis	6
Development of dominant epitope-based vaccines encoding Gp63, Kmp-11 and Amastin against visceral leishmaniasis	6
Reduced frequency and functional potency of CD49d− T regulatory cells in patients with newly diagnosed type 2 diabetes mellitus	6
Quercetin acts as a novel anti-cancer drug to suppress cancer aggressiveness and cisplatin-resistance in nasopharyngeal carcinoma (NPC) through regulating the yes-associated protein/Hippo signaling pa	6
Inactivation of the Complement Lectin Pathway by Candida tropicalis Secreted Aspartyl Protease-1	6
MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels	6
Is a negative correlation between sTNFR1 and TNF in patients with chronic Chagas disease the key to clinical progression?	6
CCR4+ monocytic myeloid-derived suppressor cells are associated with the increased epithelial-mesenchymal transition in pancreatic adenocarcinoma patients	6
TLR2 and TLR4 mRNA expression levels in liver transplant patients with acute rejection	6
Fluid shear stress enhances dendritic cell activation	5
TNF-α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor	5
Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway	5
Innate and adaptive immune responses against Influenza A Virus: Immune evasion and vaccination strategies	5
Down-regulation of miR-18b-5p protects against splenic hemorrhagic shock by directly targeting HIF-1α/iNOS pathway	5
An association of iNKT+/CD3+/CD161+ lymphocytes in ovarian cancer tissue with CA125 serum concentration	5
Arginase is involved in cervical lesions progression and severity	5
PD-L1 and PD-L2 immune checkpoint protein induction by type III interferon in non-small cell lung cancer cells	5
Vitexin along with verapamil downregulates efflux pump P-glycoprotein in macrophages and potentiate M1 to M2 switching via TLR4-NF-κB-TNFR2 pathway in lipopolysaccharide treated mice	5
Study on the additive protective effect of PGLYRP3 and Bifidobacterium adolescentis Reuter 1963 on severity of DSS-induced colitis in Pglyrp3 knockout (Pglyrp3 −/−) and wild-type (WT) mice	5
Post-translational suppression of the high affinity IgE receptor expression on mast cells by an intestinal bacterium	5
The role of dendritic cells in neuroblastoma: Implications for immunotherapy	5
Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages	5
Streptococcal arginine deiminase regulates endothelial inflammation, mTOR pathway and autophagy	5
Development of a novel trivalent invasive non-typhoidal Salmonella outer membrane vesicles based vaccine against salmonellosis and fowl typhoid in chickens	5
An optimized method to visualize the goblet cell-associated antigen passages and identify goblet cells in the intestine, conjunctiva, and airway	5
Baicalein promotes the microglia M2 polarization and suppresses apoptosis by targeting HMOX1/PDE4D to alleviate Alzheimer’s disease	5
Estrogen receptors in human bladder cells regulate innate cytokine responses to differentially modulate uropathogenic E. coli colonization	5
Association of epidermal differentiation complex (EDC) genetic variants with House Dust Mite sensitization in Atopic Dermatitis Patients	5
Monitoring of autoantibodies against CYP4Z1 in patients with colon, ovarian, or prostate cancer	5
Protective effect of two new nanovaccines against Pseudomonas aeruginosa based on LPS and OPS: A comparison study	5
STC1 ameliorates cognitive impairment and neuroinflammation of Alzheimer’s disease mice via inhibition of ERK1/2 pathway	5
Proportion of B cell subsets and Nrf2 mediated redox regulation in systemic lupus erythematosus patients	5
Expression profile of MUC1 protein in Pigeon allergens positive asthmatic	5
Comparing the expression of MiR-223-NLRP3-IL-1β axis and serum IL-1β levels in patients with severe COVID-19 and healthy individuals	4
Induced antigen-binding polyreactivity in human serum IgA	4
IL-6, IL-10, sFas, granulysin and indicators of intestinal permeability as early biomarkers for a fatal outcome in COVID-19	4
Effects of TRIM59 on RAW264.7 macrophage gene expression and function	4
Targeted genotyping of COVID-19 patients reveals a signature of complement C3 and factor B coding SNPs associated with severe infection	4
Effect of Lacticaseibacillus rhamnosus and Lactiplantibacillus plantarum isolated from food and human origin on reduction of IgE-dependent hypersensitivity in Balb/c mice	4
Diagnostic biomarkers of dilated cardiomyopathy	4
Higher proinflammatory responses possibly contributing to suppressed cytotoxicity in patients with COVID-19 associated mucormycosis	4
In-silico immunoinformatic analysis of SARS-CoV-2 virus for the development of putative vaccine construct	4
Patients with moderate to severe COVID-19 have an impaired cytokine response with an exhausted and senescent immune phenotype	4
Regulatory tumor-infiltrating lymphocytes prevail in endometrial tumors with low vascular survival ability	4
Evaluation of the anti-inflammatory effects of PI3Kδ/γ inhibitors for treating acute lung injury	4
IL-27 regulates autophagy in rheumatoid arthritis fibroblast-like synoviocytes via STAT3 signaling	4
The significance of antiglobulin (Coombs) test reactivity in patients with COVID-19	4
Formyl peptide receptor 2 (FPR2) antagonism is a potential target for the prevention of Brucella abortus 544 infection	4
Modulatory effect of rapamycin and tacrolimus on monocyte-derived dendritic cells phenotype and function	4
Omenn syndrome caused by a novel homozygous mutation in recombination activating gene 1	4
False-positive HIV serology, Candida lusitaniae pneumonia, and a novel mutation in the CYBB gene	4
Changes in extracellular cytokines in predicting disease severity and final clinical outcome of patients with blunt chest trauma	4
A multilocus genetic study evidences the association of autoimmune-related genes with Psoriatic Arthritis in Italian patients	4
ERAP1 binds peptide C-termini of different sequences and/or lengths by a common recognition mechanism	4
The role of NFAT2/miR-20a-5p signaling pathway in the regulation of CD8+ naïve T cells activation and differentiation	3
Immunomodulatory effect of dopamine in human keratinocytes and macrophages under chronical bisphenol-A exposure conditions	3
Regulatory relationship between macrophage autophagy and PVL-positive methicillin-resistant Staphylococcus aureus	3
The protective effect of total glucosides of white paeony capsules on experimental autoimmune encephalomyelitis	3
Exploring the relationship between pyroptosis, infiltrating immune cells and Kawasaki disease with resistance to intravenous immunoglobulin (IVIG) via bioinformatic analysis	3
miR-146a-5p regulates autophagy and NLRP3 inflammasome activation in epithelial barrier damage in the in vitro cell model of ulcerative colitis through the RNF8/Notch1/mTORC1 pathway	3
Down-regulation of HLA-B-associated transcript 3 impairs the tumoricidal effect of natural killer cells through promoting the T cell immunoglobulin and mucin domain-containing-3 signaling in a mouse h	3
Abatement of cyclophosphamide-induced splenic immunosuppressive indoleamine 2, 3-dioxygenase and altered hematological indices in Wister rats by dietary quercetin	3
A combined ratio change of inflammatory biomarkers at 72 h could predict the severity and prognosis of sepsis from pulmonary infections	3
Immunological screening of Lassa Virus among Health workers and Contacts of patients of Lassa fever in Ondo State	3
The oncogene ABL1 regulates the inflammatory response of innate immunity via mediating TRAF6 ubiquitination	3
Interleukin 17, the double-edged sword in atherosclerosis	3
Reduced susceptibility to COVID-19 associated with ABO blood group and pre-existing anti-A and anti-B antibodies	3
Successful perioperative management of three patients with hereditary angioedema without C1 esterase inhibitor therapy: A developing country perspective	3
The role of C5a receptors in autoimmunity	3
Non-coding RNA network associated with obesity and rheumatoid arthritis	3
Immunobiology of tubercle bacilli and prospects of immunomodulatory drugs to tackle tuberculosis (TB) and other non-tubercular mycobacterial infections	3

Maternal stress increases risk of allergic lung inflammation in adult mice	3
Hyperglycemia modulates M1/M2 macrophage polarization in chronic diabetic patients with pulmonary tuberculosis infection	3
Irisin attenuates fine particulate matter induced acute lung injury by regulating Nod2/NF-κB signaling pathway	3
Assessment of changes in immune status linked to COVID-19 convalescent and its clinical severity in patients and uninfected exposed relatives	3
CD4 and IL-2 mediated NK cell responses after COVID-19 infection and mRNA vaccination in adults	3
Properdin produced by dendritic cells contributes to the activation of T cells	3
Effects of combination of Cryptococcus gattii and IFN-γ, IL-4 or IL-27 on human bronchial epithelial cells	3
Highlighting the versatility of the citrullination process	3
Toll-like receptor 2 deficiency relieves splenic immunosuppression during sepsis	3
Opportunistic pneumonia caused by E. cuniculi in mice immunosuppressed with cyclophosphamide	3
Human macrophage immunometabolism regulator (MACIR) in patients with periodontitis	3
Down-regulation of MLLT1 super elongation complex subunit impairs the anti-tumor activity of natural killer cells in esophageal cancer	3
Expressional regulation of NKG2DLs is associated with the tumor development and shortened overall survival in lung adenocarcinoma	3
Characterization of the impact of immune checkpoint inhibitors on platelet activation and aggregation	3
Minimal structure of IRAK-1 to induce degradation of TRAF6	3
Flow cytometry profiling of cellular immune response in COVID-19 infected, recovered and vaccinated individuals	3
Role of circulating microRNA-132 in allergic bronchopulmonary aspergillosis: A case-control study	3
A small fragment of factor B as a potential inhibitor of complement alternative pathway activity	3
Effects of PFOS and cyclophosphamide exposure on immune homeostasis in mice	3
Anti-neutrophil antibodies (anti-MPO-ANCAs) are associated with poor prognosis in breast cancer patients	3
Apelin triggers macrophage polarization to M2 type in head and neck cancer	3