OOIR: Observatory of International Research

Papers

(The H4-Index of Advanced Drug Delivery Reviews is 86. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Editorial board members	998
Emerging antibiotic alternatives: From antimicrobial peptides to bacteriophage therapies	357
Opportunities and challenges in delivering biologics for Alzheimer’s disease by low-intensity ultrasound	306
Liposomal formulations for treating lysosomal storage disorders	269
Gene editing strategies to treat lysosomal disorders: The example of mucopolysaccharidoses	242
MIDD in Japan– Implementations, challenges and opportunities	229
Models to study basic and applied aspects of lysosomal storage disorders	227
Penetration and translocation of functional inorganic nanomaterials into biological barriers	218
Leveraging the neurosurgical operating room for therapeutic development in NeuroOncology	218
Bacterially mediated drug delivery and therapeutics: Strategies and advancements	214
Design, development and clinical translation of CriPec®-based core-crosslinked polymeric micelles	214
Integrating microneedles and sensing strategies for diagnostic and monitoring applications: The state of the art	198
Covalent chemistry in targeted protein degradation	196
On-Chip modeling of drug-gut interactions in Oral drug delivery	195
Recent advances in endocrine organoids for therapeutic application	193
Genome-scale metabolic modelling in antimicrobial pharmacology: Present and future	191
Progress on the pathological tissue microenvironment barrier-modulated nanomedicine	183
Deciphering albumin-directed drug delivery by imaging	179
Polymer-based drug delivery systems under investigation for enzyme replacement and other therapies of lysosomal storage disorders	174
In vitro models of the interplay between glioblastoma and blood–brain barrier for stratifying drug efficacy	170
Long-acting inhaled medicines: Present and future	169
Cell membrane-coated nanoparticles for targeting carcinogenic bacteria	165
Emerging strategies to bypass transplant rejection via biomaterial-assisted immunoengineering: Insights from islets and beyond	160
Luminescent quantum dots: Synthesis, optical properties, bioimaging and toxicity	159
Nanoparticle-neutrophils interactions for autoimmune regulation	150

Protein-based nanocarriers in the management of hard-to-treat solid tumours	149
Editorial Board	147
From molecule to absorption: a multiscale framework for subcutaneous biologic delivery	141
Editorial Board	140
Targeting microbiome, drug metabolism, and drug delivery in oncology	139
Protein encapsulation of nanocatalysts: A feasible approach to facilitate catalytic theranostics	139
Editorial/Preface	137
Emerging Voices in Drug Delivery – Harnessing and Modulating Complex Biological Systems (Issue 2)	135
iPSC-derived T cells and macrophages: Manufacturing and next-generation application approaches	134
RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer	132
Exosome- and extracellular vesicle-based approaches for the treatment of lysosomal storage disorders	124
Hydrogen sulfide in cancer therapy: Intelligent delivery platforms and synergistic therapeutic paradigms	123
3D printing of drug delivery systems enhanced with micro/nano-technology	119
Nanoparticles-mediated ion channels manipulation: From their membrane interactions to bioapplications	119
Activatable fluorescent probes for real-time imaging-guided tumor therapy	119
Novel strategies for modulating the gut microbiome for cancer therapy	118
In situ cellular hitchhiking of nanoparticles for drug delivery	117
Red to near-infrared carbon dots: synthesis, cellular interactions, drug loading, and therapeutic applications	116
Strategies to develop polymeric microneedles for controlled drug release	116
Biopharmaceutical drug delivery and phototherapy using protein crystals	111
Biomarker and therapeutic potential of peripheral extracellular vesicles in Alzheimer’s disease	110
Synthetic biology-guided design and biosynthesis of protein polymers for delivery	109
From cells to subcellular organelles: Next-generation cancer therapy based on peptide self-assembly	108
Small data, big challenges: Machine- and deep-learning strategies for data-limited drug discovery	107
Quality by Computational Design: Harnessing AI to Advance Rational Drug Development	107
Pulmonary delivery nanomedicines towards circumventing physiological barriers: Strategies and characterization approaches	106
Drug delivery using gold nanoparticles	105
Solid implantable devices for sustained drug delivery	104
Activatable dual-functional molecular agents for imaging-guided cancer therapy	103
Emerging drug delivery systems with traditional routes – A roadmap to chronic inflammatory diseases	103
Miniaturized therapeutic systems for ultrasound-modulated drug delivery to the central and peripheral nervous system	102
Unignored intracellular journey and biomedical applications of extracellular vesicles	102
Lipid nanoparticles for targeted delivery of anticancer therapeutics: Recent advances in development of siRNA and lipoprotein-mimicking nanocarriers	101
Technology for Nucleic Acid Delivery in the Treatment of Hematological Malignancies	99
Lysosomal therapies and drug delivery strategies: An overview	99
Hurdles in translating science from lab to market in delivery systems for Cosmetics: An industrial perspective	98
Engineering bacterial membrane nanovesicles for improved therapies in infectious diseases and cancer	98
Tumour extravasation of nanomedicine: The EPR and alternative pathways	97
Nanosensitizer-mediated unique dynamic therapy tactics for effective inhibition of deep tumors	97
Therapeutic gases as emerging treatments for oral diseases	96
Novel drug delivery systems for the management of dry eye	95
Tumor microenvironment subtyping in pancreatic ductal adenocarcinoma: New avenues for personalized therapeutic strategies	93
Soft nano and microstructures for the photomodulation of cellular signaling and behavior	93
Light sheet fluorescence microscopy for monitoring drug delivery: Unlocking the developmental phases of embryos	93
Advances in photoactivated carbon-based nanostructured materials for targeted cancer therapy	92
Fit and forget: The future of dental implant therapy via nanotechnology	92
Convection-enhanced delivery for brain malignancies: Technical parameters, formulation strategies and clinical perspectives	92
Nanobodies: Robust miniprotein binders in biomedicine	91
Matrix-integrated microfluidic tumor models for evaluating drug delivery systems and pre-clinical testing	91
Model-informed precision dosing: State of the art and future perspectives	90

Antibody-drug conjugates as multimodal therapies against hard-to-treat cancers	90
Overcoming therapy resistance in pancreatic cancer: challenges and emerging strategies	89
Preface: Image-assisted organoid research and application	89
Editorial Board	88
Corrigendum to “Editorial: Advanced strategies to bridge the gap between inflammation and tissue regeneration” [Adv. Drug Deliv. Rev. 209 (2024) 115328]	88
MicroRNA-targeting nanomedicines for the treatment of intervertebral disc degeneration	88
Editorial board members	88
Harnessing reactive oxygen species for precision medicine: ROS-Activatable PROTACs for lung Cancer	88
Design principles for construction of DNA-based nanostructures	87
Engineering tissue patterning in human stem cell-based embryo models	87
Rational modification of PROTACs for tumor-selective protein degradation	86
Beyond the adverse effects of the systemic route: Exploiting nanocarriers for the topical treatment of skin cancers	86