OOIR: Observatory of International Research

Papers

(The H4-Index of Advanced Drug Delivery Reviews is 89. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Drug delivery strategies in maximizing anti-angiogenesis and anti-tumor immunity	534
Leveraging the neurosurgical operating room for therapeutic development in NeuroOncology	533
Drug delivery for metabolism targeted cancer immunotherapy	322
Opportunities and challenges in delivering biologics for Alzheimer’s disease by low-intensity ultrasound	250
Agony of choice: How anesthetics affect the composition and function of extracellular vesicles	248
Editorial board members	244
Emerging antibiotic alternatives: From antimicrobial peptides to bacteriophage therapies	242
Long-acting inhaled medicines: Present and future	238
Gene editing strategies to treat lysosomal disorders: The example of mucopolysaccharidoses	230
Deciphering albumin-directed drug delivery by imaging	217
Nanoparticle-neutrophils interactions for autoimmune regulation	213
Integrating microneedles and sensing strategies for diagnostic and monitoring applications: The state of the art	200
Recent applications of electrical, centrifugal, and pressurised emerging technologies for fibrous structure engineering in drug delivery, regenerative medicine and theranostics	198
Tools for computational design and high-throughput screening of therapeutic enzymes	195
Bacterially mediated drug delivery and therapeutics: Strategies and advancements	191
Polymer-based drug delivery systems under investigation for enzyme replacement and other therapies of lysosomal storage disorders	188
Emerging strategies to bypass transplant rejection via biomaterial-assisted immunoengineering: Insights from islets and beyond	176
Models to study basic and applied aspects of lysosomal storage disorders	169
MIDD in Japan– Implementations, challenges and opportunities	168
Progress on the pathological tissue microenvironment barrier-modulated nanomedicine	165
Recent advances in endocrine organoids for therapeutic application	161
Mastering the Gram-negative bacterial barrier – Chemical approaches to increase bacterial bioavailability of antibiotics	158
Design, development and clinical translation of CriPec®-based core-crosslinked polymeric micelles	158
Cell membrane-coated nanoparticles for targeting carcinogenic bacteria	154
Penetration and translocation of functional inorganic nanomaterials into biological barriers	149

Liposomal formulations for treating lysosomal storage disorders	149
Therapeutic and delivery strategies of phytoconstituents for renal fibrosis	144
MicroRNAs and their delivery in diabetic fibrosis	143
Nanoparticle designs for delivery of nucleic acid therapeutics as brain cancer therapies	139
Nanovaccines with cell-derived components for cancer immunotherapy	137
Luminescent quantum dots: Synthesis, optical properties, bioimaging and toxicity	137
Biopharmaceutical drug delivery and phototherapy using protein crystals	134
Editorial/Preface	131
Emerging Voices in Drug Delivery – Harnessing and Modulating Complex Biological Systems (Issue 2)	129
In vitro-in vivo correlation of cascade impactor data for orally inhaled pharmaceutical aerosols	127
Biomarker and therapeutic potential of peripheral extracellular vesicles in Alzheimer’s disease	127
Activatable dual-functional molecular agents for imaging-guided cancer therapy	126
Editorial Board	126
Targeting microbiome, drug metabolism, and drug delivery in oncology	121
Drug delivery using gold nanoparticles	121
Lipid nanoparticle formulations for targeting leukocytes with therapeutic RNA in liver fibrosis	120
RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer	118
Protein encapsulation of nanocatalysts: A feasible approach to facilitate catalytic theranostics	118
Exosome- and extracellular vesicle-based approaches for the treatment of lysosomal storage disorders	118
Role of extracellular vesicles in liver diseases and their therapeutic potential	118
From cells to subcellular organelles: Next-generation cancer therapy based on peptide self-assembly	118
Drug development of lyso-thermosensitive liposomal doxorubicin: Combining hyperthermia and thermosensitive drug delivery	113
Separation, characterization, and standardization of extracellular vesicles for drug delivery applications	112
In situ cellular hitchhiking of nanoparticles for drug delivery	112
Oral delivery of natural active small molecules by polymeric nanoparticles for the treatment of inflammatory bowel diseases	112
Synthetic biology-guided design and biosynthesis of protein polymers for delivery	112
Pulmonary delivery nanomedicines towards circumventing physiological barriers: Strategies and characterization approaches	109
Ultrasonic particles: An approach for targeted gene delivery	109
Novel strategies for modulating the gut microbiome for cancer therapy	109
Physical methods for enhancing drug absorption from the gastrointestinal tract	106
3D printing of drug delivery systems enhanced with micro/nano-technology	105
Strategies to develop polymeric microneedles for controlled drug release	105
Multifaceted role of phyto-derived polyphenols in nanodrug delivery systems	103
Activatable fluorescent probes for real-time imaging-guided tumor therapy	102
Solid implantable devices for sustained drug delivery	102
Nanoparticles-mediated ion channels manipulation: From their membrane interactions to bioapplications	101
Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers	100
Lysosomal therapies and drug delivery strategies: An overview	99
Engineering bacterial membrane nanovesicles for improved therapies in infectious diseases and cancer	99
Phytonanomaterials as therapeutic agents and drug delivery carriers	99
Miniaturized therapeutic systems for ultrasound-modulated drug delivery to the central and peripheral nervous system	99
Hurdles in translating science from lab to market in delivery systems for Cosmetics: An industrial perspective	98
Nanosensitizer-mediated unique dynamic therapy tactics for effective inhibition of deep tumors	98
Lipid nanoparticles for targeted delivery of anticancer therapeutics: Recent advances in development of siRNA and lipoprotein-mimicking nanocarriers	97
Light sheet fluorescence microscopy for monitoring drug delivery: Unlocking the developmental phases of embryos	97
The extracellular matrix of hematopoietic stem cell niches	96
Nanobodies: Robust miniprotein binders in biomedicine	95
Vaginal drug delivery approaches for localized management of cervical cancer	94
Technological and translational challenges for extracellular vesicle in therapy and diagnosis	94
Model-informed precision dosing: State of the art and future perspectives	94

Modular design principle based on compartmental drug delivery systems	94
Micro-patterned cell populations as advanced pharmaceutical drugs with precise functional control	94
Engineering complexity in human tissue models of cancer	94
Emerging drug delivery systems with traditional routes – A roadmap to chronic inflammatory diseases	93
Soft nano and microstructures for the photomodulation of cellular signaling and behavior	93
Drug delivery strategies for management of women’s health issues in the upper genital tract	92
Recent trends in drug-delivery systems for the treatment of diabetic retinopathy and associated fibrosis	92
Tumour extravasation of nanomedicine: The EPR and alternative pathways	92
In-vitro 3D modelling for charged particle therapy – Uncertainties and opportunities	92
Novel drug delivery systems for the management of dry eye	91
Unignored intracellular journey and biomedical applications of extracellular vesicles	91
To PEGylate or not to PEGylate: Immunological properties of nanomedicine’s most popular component, polyethylene glycol and its alternatives	90
Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities	90
Editorial board members	89
Fit and forget: The future of dental implant therapy via nanotechnology	89
Editorial board members	89
High-throughput proteomics and AI for cancer biomarker discovery	89