OOIR: Observatory of International Research

Papers

(The H4-Index of Advanced Drug Delivery Reviews is 84. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Gene editing strategies to treat lysosomal disorders: The example of mucopolysaccharidoses	789
Editorial board members	405
Emerging antibiotic alternatives: From antimicrobial peptides to bacteriophage therapies	320
Genome-scale metabolic modelling in antimicrobial pharmacology: Present and future	319
MIDD in Japan– Implementations, challenges and opportunities	287
Leveraging the neurosurgical operating room for therapeutic development in NeuroOncology	279
Integrating microneedles and sensing strategies for diagnostic and monitoring applications: The state of the art	257
Nanoparticle-neutrophils interactions for autoimmune regulation	214
Penetration and translocation of functional inorganic nanomaterials into biological barriers	213
Drug delivery for metabolism targeted cancer immunotherapy	205
In vitro models of the interplay between glioblastoma and blood–brain barrier for stratifying drug efficacy	190
Models to study basic and applied aspects of lysosomal storage disorders	188
Long-acting inhaled medicines: Present and future	185
Liposomal formulations for treating lysosomal storage disorders	173
Polymer-based drug delivery systems under investigation for enzyme replacement and other therapies of lysosomal storage disorders	168
Emerging strategies to bypass transplant rejection via biomaterial-assisted immunoengineering: Insights from islets and beyond	164
Design, development and clinical translation of CriPec®-based core-crosslinked polymeric micelles	164
Deciphering albumin-directed drug delivery by imaging	158
Nanovaccines with cell-derived components for cancer immunotherapy	157
Tools for computational design and high-throughput screening of therapeutic enzymes	154
Luminescent quantum dots: Synthesis, optical properties, bioimaging and toxicity	150
Drug delivery strategies in maximizing anti-angiogenesis and anti-tumor immunity	149
Nanoparticle designs for delivery of nucleic acid therapeutics as brain cancer therapies	148
Cell membrane-coated nanoparticles for targeting carcinogenic bacteria	147
Opportunities and challenges in delivering biologics for Alzheimer’s disease by low-intensity ultrasound	145

Progress on the pathological tissue microenvironment barrier-modulated nanomedicine	144
Bacterially mediated drug delivery and therapeutics: Strategies and advancements	141
MicroRNAs and their delivery in diabetic fibrosis	137
Editorial Board	135
Recent advances in endocrine organoids for therapeutic application	135
Synthetic biology-guided design and biosynthesis of protein polymers for delivery	128
From cells to subcellular organelles: Next-generation cancer therapy based on peptide self-assembly	127
Protein encapsulation of nanocatalysts: A feasible approach to facilitate catalytic theranostics	127
Editorial/Preface	123
Targeting microbiome, drug metabolism, and drug delivery in oncology	121
Emerging Voices in Drug Delivery – Harnessing and Modulating Complex Biological Systems (Issue 2)	120
Biopharmaceutical drug delivery and phototherapy using protein crystals	119
Novel strategies for modulating the gut microbiome for cancer therapy	118
Hydrogen sulfide in cancer therapy: Intelligent delivery platforms and synergistic therapeutic paradigms	118
Biomarker and therapeutic potential of peripheral extracellular vesicles in Alzheimer’s disease	117
iPSC-derived T cells and macrophages: Manufacturing and next-generation application approaches	116
Activatable dual-functional molecular agents for imaging-guided cancer therapy	116
RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer	115
Nanoparticles-mediated ion channels manipulation: From their membrane interactions to bioapplications	114
Exosome- and extracellular vesicle-based approaches for the treatment of lysosomal storage disorders	113
Strategies to develop polymeric microneedles for controlled drug release	112
Ultrasonic particles: An approach for targeted gene delivery	112
In situ cellular hitchhiking of nanoparticles for drug delivery	109
Pulmonary delivery nanomedicines towards circumventing physiological barriers: Strategies and characterization approaches	108
Drug delivery using gold nanoparticles	105
Activatable fluorescent probes for real-time imaging-guided tumor therapy	104
Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers	103
Solid implantable devices for sustained drug delivery	102
In-vitro 3D modelling for charged particle therapy – Uncertainties and opportunities	101
3D printing of drug delivery systems enhanced with micro/nano-technology	101
Technological and translational challenges for extracellular vesicle in therapy and diagnosis	100
Lysosomal therapies and drug delivery strategies: An overview	100
Micro-patterned cell populations as advanced pharmaceutical drugs with precise functional control	99
Convection-enhanced delivery for brain malignancies: Technical parameters, formulation strategies and clinical perspectives	98
Engineering bacterial membrane nanovesicles for improved therapies in infectious diseases and cancer	98
Nanobodies: Robust miniprotein binders in biomedicine	97
Soft nano and microstructures for the photomodulation of cellular signaling and behavior	96
Emerging drug delivery systems with traditional routes – A roadmap to chronic inflammatory diseases	96
Miniaturized therapeutic systems for ultrasound-modulated drug delivery to the central and peripheral nervous system	94
Light sheet fluorescence microscopy for monitoring drug delivery: Unlocking the developmental phases of embryos	91
Fit and forget: The future of dental implant therapy via nanotechnology	91
Model-informed precision dosing: State of the art and future perspectives	90
Lipid nanoparticles for targeted delivery of anticancer therapeutics: Recent advances in development of siRNA and lipoprotein-mimicking nanocarriers	90
Unignored intracellular journey and biomedical applications of extracellular vesicles	90
Antibody-drug conjugates as multimodal therapies against hard-to-treat cancers	89
Nanosensitizer-mediated unique dynamic therapy tactics for effective inhibition of deep tumors	89
Overcoming therapy resistance in pancreatic cancer: challenges and emerging strategies	89
The extracellular matrix of hematopoietic stem cell niches	89
Novel drug delivery systems for the management of dry eye	89
To PEGylate or not to PEGylate: Immunological properties of nanomedicine’s most popular component, polyethylene glycol and its alternatives	89

Engineering complexity in human tissue models of cancer	88
Tumor microenvironment subtyping in pancreatic ductal adenocarcinoma: New avenues for personalized therapeutic strategies	87
Tumour extravasation of nanomedicine: The EPR and alternative pathways	87
Advances in photoactivated carbon-based nanostructured materials for targeted cancer therapy	87
Hurdles in translating science from lab to market in delivery systems for Cosmetics: An industrial perspective	86
Corrigendum to “Editorial: Advanced strategies to bridge the gap between inflammation and tissue regeneration” [Adv. Drug Deliv. Rev. 209 (2024) 115328]	85
Oral nanomedicine biointeractions in the gastrointestinal tract in health and disease	84
Preface: Image-assisted organoid research and application	84
Responsive nanomedicines enhanced by or enhancing physical modalities to treat solid cancer tumors: Preclinical and clinical evidence of safety and efficacy	84
Editorial Board	84