Trends in Genetics

Article	Citations
Subscription and Copyright Information	585
Advisory Board and Contents	548
Emerging regulatory mechanisms of noncoding RNAs in topologically associating domains	459
Carcinoscorpius rotundicauda (mangrove horseshoe crab)	249
Crossover recombination between homologous chromosomes in meiosis: recent progress and remaining mysteries	191
Heritable epigenetic changes at single genes: challenges and opportunities in Caenorhabditis elegans	170
Omics studies of DNA G-/C-quadruplexes in plants	165
Subscription and Copyright Information	154
Advisory Board and Contents	147
Advisory Board and Contents	141
Genomic instability signals offer diagnostic possibility in early cancer detection	140
Assessing autosomal aneuploidy in ancient genomes	137
Genetic buffering mechanisms in SNF2-family translocases	122
Epigenetic networks driving T cell identity and plasticity during immunosenescence	114
The complex universe of inactive PARP1	113
PCNA cycling dynamics during DNA replication and repair in mammals	101
Long Noncoding RNAs at the Crossroads of Cell Cycle and Genome Integrity	101
Intron retention: importance, challenges, and opportunities	99
Emerging functions of circular RNA in aging	98
The sound of silence: mechanisms and implications of HUSH complex function	95
Pursuing totipotency: authentic totipotent stem cells in culture	84
Superspreading in the emergence of COVID-19 variants	84
Advisory Board and Contents	77
Variation on a theme: mapping microglial heterogeneity	77
Immunity and lifespan: answering long-standing questions with comparative genomics	77

Opportunities and challenges for artificial intelligence in clinical cardiovascular genetics	74
Evolution of piRNA-guided defense against transposable elements	70
The chromatin roots of abnormal splicing in autism	70
Genome structural variation in human evolution	69
Multi-omic genetic scores advance disease research	67
A new hypothesis to explain disease dominance	67
A three-dimensional genomics view for speciation research	66
Advisory Board and Contents	65
Histone lactylation: epigenetic mark of glycolytic switch	65
Advisory Board and Contents	64
Revealing microRNA regulation in single cells	59
Clonal ants reveal a potentially hidden meiotic feature	59
DNA base editing in nuclear and organellar genomes	58
Progress and opportunities through use of genomics in animal production	57
Insights into Spt6: a histone chaperone that functions in transcription, DNA replication, and genome stability	56
From genetic associations to genes: methods, applications, and challenges	52
Ionizing radiation damage and repair from 3D-genomic perspective	52
Canis familiaris (Great Dane domestic dog)	52
Subscription and Copyright Information	49
Advisory Board and Contents	48
The making and breaking of tRNAs by ribonucleases	47
Finding functional microproteins	47
Dynamics of the Streptomyces chromosome: chance and necessity	46
Cis to trans: small ORF functions emerging through evolution	46
Pioneer factors: roles and their regulation in development	46
Subscription and Copyright Information	45
Genetic architecture of brain morphology and overlap with neuropsychiatric traits	45
Advisory Board and Contents	45
Exploring the world of small proteins in plant biology and bioengineering	44
Subscription and Copyright Information	42
Leveraging microbiome information for animal genetic improvement	42
Unraveling the diversity and cultural heritage of fruit crops through paleogenomics	41
Does TFIIH move nucleosomes?	40
Extracellular vesicles as modifiers of epigenomic profiles	40
Wheat genomics: genomes, pangenomes, and beyond	40
The Nexus of cfDNA and Nuclease Biology	38
There is another: H3K27me3-mediated genomic imprinting	38
From QTL to gene: C. elegans facilitates discoveries of the genetic mechanisms underlying natural variation	38
Callithrix jacchus (the common marmoset)	37
Dissecting super-enhancer heterogeneity: time to re-examine cancer subtypes?	37
Open practices in our science and our courtrooms	37
Advisory Board and Contents	36
Directing RNA-modifying machineries towards endogenous RNAs: opportunities and challenges	36
mRNA-binding proteins and cell cycle progression	36
Advisory Board and Contents	36
The origins and evolution of translation factors	36
Earth Biogenome Project: present status and future plans	35
Singling out motor neurons in the age of single-cell transcriptomics	35
Mapping cellular responses to DNA double-strand breaks using CRISPR technologies	34
Transcriptional Silencers: Driving Gene Expression with the Brakes On	34

Positive-strand RNA virus genome replication organelles: structure, assembly, control	33
Evolutionary impact of chimeric RNAs on generating phenotypic plasticity in human cells	33
Polycomb Gene Silencing Mechanisms: PRC2 Chromatin Targeting, H3K27me3 'Readout', and Phase Separation-Based Compaction	33
A current guide to candidate gene association studies	32
Subscription and Copyright Information	32
Clonal selection parallels between normal and cancer tissues	32
Research and leaders: a twisted tale!	31
Rare variants and handedness: spotlight on TUBB4B	31
Cocos nucifera (coconut)	30
Low-cost CRISPR diagnostics for resource-limited settings	29
Genetics of human handedness: microtubules and beyond	29
Dosage compensation in non-model insects – progress and perspectives	29
Convergent evolution for antibiotic biosynthesis in bacteria and animals	28
The influence of transposable elements on animal colouration	28
Complex genomic rearrangements: an underestimated cause of rare diseases	27
Clocks at sea: the genome-editing tide is rising	27
Chromoanagenesis in plants: triggers, mechanisms, and potential impact	27
Mitochondrial-derived microproteins: from discovery to function	27
Beyond sequencing: machine learning algorithms extract biology hidden in Nanopore signal data	26
The H2A.Z-nucleosome code in mammals: emerging functions	26
Horizontal Gene Transfer in Vertebrates: A Fishy Tale	26
Subscription and Copyright Information	25
Evolving a favorable distribution for mutation effects	25
The cell as a bag of RNA	25
Advisory Board and Contents	24
The Curious Case of Avian Sex Determination	24
Subscription and Copyright Information	24
Subscription and Copyright Information	24
Subscription and Copyright Information	23
Is it time to reassess variant annotation?	23
A new Down syndrome rat model races forward	23
Complexities of mammalian transcriptome revealed by targeted RNA enrichment techniques	22
Subscription and Copyright Information	22
Subscription and Copyright Information	22
Driving to Safety: CRISPR-Based Genetic Approaches to Reducing Antibiotic Resistance	22
Emerging insights into the genetics and evolution of human same-sex sexual behavior	22
The essential but enigmatic regulatory role of HERVH in pluripotency	21
Integration of DNA damage responses with dynamic spatial genome organization	21
Into the multiverse: advances in single-cell multiomic profiling	21
Long-read transcriptome sequencing reveals allele-specific variants at high resolution	21
The impact of IDR phosphorylation on the RNA binding profiles of proteins	21
Histone Ubiquitination: An Integrative Signaling Platform in Genome Stability	21
In search of a cure: PACS1 Research Foundation as a model of rare disease therapy development	21
Tissue specificity of DNA repair: the CRISPR compass	21
Current concepts, advances, and challenges in deciphering the human microbiota with metatranscriptomics	20
Advisory Board and Contents	20
Repetitive elements in aging and neurodegeneration	20
The versatile relationships between eIF4E and eIF4E-interacting proteins	20
Predicting genome organisation and function with mechanistic modelling	20
Subscription and Copyright Information	19
Are phenome-wide association studies feasible in a developing country?	19
Across the North Sea and beyond	19
Advisory Board and Contents	19
Bear essentials	19
The genome atlas: navigating a new era of reference genomes	18
Zebrafish and idiopathic scoliosis: the ‘unknown knowns’	18
Recursive Test of Hardy-Weinberg Equilibrium in Tetraploids	18
Mendelian randomization analyses for PCOS: evidence, opportunities, and challenges	18
Dynamics of replication timing during mammalian development	18
Genome stability from the perspective of telomere length	18
DNA lesions piece together impossible trees	18
The ribosome’s comeback: new role in body weight regulation	18
Computational methods for allele-specific expression in single cells	18
Quantitative genetics: pan-genomes, SVs, and k-mers for GWAS	17
Mitochondria and G-quadruplex evolution: an intertwined relationship	17
Emerging functions of mitochondria-encoded noncoding RNAs	17
Underappreciated Roles of DNA Polymerase δ in Replication Stress Survival	16
The searchable chromosome	16
Subscription and Copyright Information	16
Honeybees’ novel complementary sex-determining system: function and origin	16
Noncanonical DNA structures are drivers of genome evolution	16
Modeling the origin of cells	16
Advisory Board and Contents	16
Mitochondrial-derived microproteins: from discovery to function	16
DNA methylation: a historical perspective	16
Genomic newborn screening: exploring opportunities and navigating pitfalls while ensuring inclusivity	16
Chromatin accessibility provides a window into the genetic etiology of human brain disease	16
The wild side of grape genomics	15
Approaches and challenges in genome-wide circular RNA identification and quantification	15
Opportunities and tradeoffs in single-cell transcriptomic technologies	15

Maturation and application of phenome-wide association studies	15
Insights from multi-omics integration in complex disease primary tissues	15
Whole-genome doubling in tissues and tumors	15
Subscription and Copyright Information	14
Advancing evolutionary medicine with complete primate genomes and advanced biotechnologies	14
Subscription and Copyright Information	14
Advisory Board and Contents	14
Ginkgo biloba	14
Finding genes and pathways that underlie coral adaptation	14
Noncoding snoRNA host genes are a distinct subclass of long noncoding RNAs	14
iPSC-derived organ-on-a-chip models for personalized human genetics and pharmacogenomics studies	13
Yes, polygenic sex determination is a thing!	13
Breakage in breakage–fusion–bridge cycle: an 80-year-old mystery	13
Genetic adaptations for the oceanic success of fish eggs	13
ATRX, a guardian of chromatin	13
Interplay between regulatory elements and chromatin topology in cellular lineage determination	12
Selective REcruitmeNt of plant DNA polymerases by geminivirus	12
Subscription and Copyright Information	12
Advisory Board and Contents	12
Open Access: A Role for p53 in c9ALS/FTD?	12
Advisory Board and Contents	12
Advances in methods for tRNA sequencing and quantification	12
Selective Xi reactivation and alternative methods to restore MECP2 function in Rett syndrome	12
ReNU syndrome – a newly discovered prevalent neurodevelopmental disorder	11
An updated view of the kinetochore architecture	11
Every gene can (and possibly will) be associated with cancer	11
Starships: a new frontier for fungal biology	11
A multi-epigenomic map of endurance exercise training	11
Chromatin-centric insights into DNA replication	11
Cis-regulatory dynamics in plant domestication	11
Genetic and epigenetic defects of the RNA modification machinery in cancer	11
Nuclear Periphery and Telomere Maintenance: TERRA Joins the Stage	11
New insights into oocyte cytoplasmic lattice-associated proteins	10
Advisory Board and Contents	10
ADAR1 and its implications in cancer development and treatment	10
Subscription and Copyright Information	10
Fun-sized and fundamental	10
miRNA biogenesis and inherited disorders: clinico-molecular insights	10
Aneuploidy in human cancer: new tools and perspectives	10
A blood drop through the pore: nanopore sequencing in hematology	10
Transposon–host arms race: a saga of genome evolution	9
Take a walk on the KRAB side	9
Evolutionary cell type mapping with single-cell genomics	9
Recent insights into eukaryotic double-strand DNA break repair unveiled by single-molecule methods	9
Subscription and Copyright Information	9
Chromosome-scale haplotype-resolved pangenomics	9
Cats – telomere to telomere and nose to tail	9
Patient privacy in AI-driven omics methods	9
People with disability and privacy in precision medicine research: what’s at stake?	9
Genetic disorders of cellular trafficking	9
Subscription and Copyright Information	8
Out of the dark: the emerging roles of lncRNAs in pain	8
Haldane’s duel: intragenomic conflict, selfish Y chromosomes and speciation	8
Emerging links between phase separation and transcription factor haploinsufficiency	8
Gene-dosage issues: a recurrent theme in whole genome duplication events	8
Advisory Board and Contents	8
The impact of human accelerated regions on neuronal development	8
Preventing excess replication origin activation to ensure genome stability	8
Leveraging spatial multiomics to unravel tissue architecture in embryo development	7
The New RNA-Editing Era – Ethical Considerations	7
FIRRM and FIGNL1: partners in the regulation of homologous recombination	7
Time is ticking faster for long genes in aging	7
Duplicated gene networks promote ‘hopeful’ phenotypic variation	7
The evolution of the GALactose utilization pathway in budding yeasts	7
Multiple sclerosis: doubling down on MHC	7
From darkness to discovery: evolutionary, adaptive, and translational genetic insights from cavefish	7
Molecular animations in genomics education: designing for whom?	7
Functional characterization of human genomic variation linked to polygenic diseases	7
A dive into the unknome	7
DEAD/DEAH-box RNA helicases shape the risk of neurodevelopmental disorders	7
Supergenes promote ecological stasis in a keystone species	6
Single-cell dissection of tumor microenvironmental response and resistance to cancer therapy	6
Studying transcription factor function in the genome at molecular resolution	6
Advisory Board and Contents	6
Bridging biological cfDNA features and machine learning approaches	6
The evolution of aging and lifespan	6
Strategies for dissecting the complexity of neurodevelopmental disorders	6
Retrotransposon renaissance in early embryos	6
The multifaceted effects of YTHDC1-mediated nuclear m6A recognition	6
Exploring the Alternative Splicing of Long Noncoding RNAs	6
Epigenetic control of muscle stem cells: time for a new dimension	6
Women and Minorities Encouraged to Apply (Not Stay)	6
Subscription and Copyright Information	6
Structure-specific nucleases: role in Okazaki fragment maturation	6
Picochlorum sp. SENEW3	6
Symbiodinium microadriaticum (coral microalgal endosymbiont)	6
Advisory Board and Contents	6
Aegilops tauschii presents a genetic roadmap for hexaploid wheat improvement	6
New mechanism of chromatin compartmentalization by BRD2	6
HMGs as rheostats of chromosomal structure and cell proliferation	6
Gene reporters for magnetic resonance imaging	6
Advisory Board and Contents	6
Achieve your research goals: a project management toolkit for graduate studies	6
Therapeutic and prognostic insights from the analysis of cancer mutational signatures	6
Subscription and Copyright Information	6