Journal of Controlled Release

Papers
(The TQCC of Journal of Controlled Release is 19. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Self-assembled hyaluronic acid nanoparticles for the topical treatment of inflammatory skin diseases: Beyond drug carriers561
Protein and peptide-based renal targeted drug delivery systems457
Autophagy-modulating biomembrane nanostructures: A robust anticancer weapon by modulating the inner and outer cancer environment353
Intradermal delivery of the antiretroviral drugs cabotegravir and rilpivirine by dissolving microarray patches: Investigation of lymphatic uptake332
Branched pegylated linker-auristatin to control hydrophobicity for the production of homogeneous minibody-drug conjugate against HER2-positive breast cancer265
Polymyxin B-targeted liposomal photosensitizer cures MDR A. baumannii burn infections and accelerates wound healing via M1/M2 macrophage polarization242
Microneedle-mediated nose-to-brain drug delivery for improved Alzheimer's disease treatment199
Enhancing gene transfection of poly(β-amino ester)s through modulation of amphiphilicity and chain sequence197
Recent advances in drug delivery and targeting for the treatment of pancreatic cancer196
Ferroptosis boosted oral cancer photodynamic therapy by carrier-free Sorafenib-Ce6 self-assembly nanoparticles196
Electromechanical convective drug delivery devices for overcoming diffusion barriers196
Development of anti-PEG IgG/IgM/IgE ELISA assays for profiling anti-PEG immunoglobulin response in PEG-sensitized individuals and patients with alpha-gal allergy195
Engineered exosomes with enhanced stability and delivery efficiency for glioblastoma therapy192
Engineered liposomes targeting hepatic stellate cells overcome pathological barriers and reverse liver fibrosis185
Efficient gene delivery by multifunctional star poly (β-amino ester)s into difficult-to-transfect macrophages for M1 polarization184
Differentiated mesenchymal stem cells-derived exosomes immobilized in decellularized sciatic nerve hydrogels for peripheral nerve repair180
Mesoporous zinc oxide-based drug delivery system offers an antifungal and immunoregulatory strategy for treating keratitis178
STING-activating cyclic dinucleotide-manganese nanoparticles evoke robust immunity against acute myeloid leukemia171
Inside Back Cover165
Smart exosomes enhance PDAC targeted therapy161
Bacteria-based drug delivery for treating non-oncological diseases160
Glucose-responsive insulin microneedle patches for long-acting delivery and release visualization160
ROS-driven supramolecular nanoparticles exhibiting efficient drug delivery for chemo/Chemodynamic combination therapy for Cancer treatment159
Outside Back Cover153
A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes152
Tailoring carrier-free nanocombo of small-molecule prodrug for combinational cancer therapy152
An antibacterial, multifunctional nanogel for efficient treatment of neutrophilic asthma145
Recent nanoengineered diagnostic and therapeutic advancements in management of Sepsis144
Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions142
Inhaled deep eutectic solvent based-nanoemulsion of pirfenidone in idiopathic pulmonary fibrosis140
Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma?138
Metal-organic frameworks: A promising option for the diagnosis and treatment of Alzheimer's disease138
Evolution of drug delivery systems: From 1950 to 2020 and beyond133
An oxidative stress-responsive electrospun polyester membrane capable of releasing anti-bacterial and anti-inflammatory agents for postoperative anti-adhesion128
PEG length effect of peptide-functional liposome for blood brain barrier (BBB) penetration and brain targeting125
Intraperitoneal drug delivery systems for peritoneal carcinomatosis: Bridging the gap between research and clinical implementation124
Cavitation-assisted sonothrombolysis by asymmetrical nanostars for accelerated thrombolysis123
Fatty acid conjugated EPI-X4 derivatives with increased activity and in vivo stability122
Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors119
Cardiac delivery of modified mRNA using lipid nanoparticles: Cellular targets and biodistribution after intramyocardial administration115
Cryogel microcarriers for sustained local delivery of growth factors to the brain115
The colon targeting efficacies of mesalazine medications and their impacts on the gut microbiome114
Spatiotemporally-controlled hydrophobic drug delivery via photosensitizer-driven assembly-disassembly for enhanced triple-negative breast cancer treatment114
Microparticle fabricated from a series of symmetrical lipids based on dihydroxyacetone form textured architectures109
Transform nanomedicine with breakthrough thinking?109
Site-specific nanoswitch circumventing immune resistance via activating TLR and inhibiting PD-L1/PD-1 axis109
Outside Back Cover108
Nanoparticle platform comprising lipid-tailed pH-sensitive carbon dots with minimal drug loss108
A therapeutic DC vaccine with maintained immunological activity exhibits robust anti-tumor efficacy107
Spatially regulated activation of membrane fusogenic peptides with chaperone-like ionic copolymers106
Outside Front Cover106
Engineered peptide-drug conjugate provides sustained protection of retinal ganglion cells with topical administration in rats105
Prediction of drug capturing by lipid emulsions in vivo for the treatment of a drug overdose103
Content list including Graphcal Abstracts103
Outside Back Cover102
Outside Back Cover101
Inside Back Cover100
Targeted delivery of CD163+ macrophage-derived small extracellular vesicles via RGD peptides promote vascular regeneration and stabilization after spinal cord injury99
Letter to the editor regarding “Translation of focused ultrasound for blood-brain barrier opening in glioma”97
Protein corona-driven nanovaccines improve antigen intracellular release and immunotherapy efficacy96
Surgical management of peritoneal metastasis: Opportunities for pharmaceutical research96
Mechanisms of cellular retention of melanin bound drugs: Experiments and computational modeling96
Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance94
Dendrimer-enabled targeted delivery attenuates glutamate excitotoxicity and improves motor function in a rabbit model of cerebral palsy93
A tribute to my biosimilar91
Contents list including Graphcal Abstracts89
Editorial Board89
Inside Front Cover88
Controlled delivery systems are the cornerstone of advanced therapies and vaccines: An Asian perspective88
Editorial Board87
An injectable carrier for spatiotemporal and sequential release of therapeutic substances to treat myocardial infarction87
Antigen-specific T cell activation through targeted delivery of in-situ generated antigen and calcium ionophore to enhance antitumor immunotherapy86
Photochemical internalization (PCI)-mediated activation of CD8 T cells involves antigen uptake and CCR7-mediated transport by migratory dendritic cells to draining lymph nodes85
Dynamic immuno-nanomedicines in oncology85
Inside Front Cover84
Combination Organelle Mitochondrial Endoplasmic Reticulum Therapy (COMET) for Multidrug Resistant Breast Cancer84
Small EV-based delivery of CpG ODNs for melanoma postsurgical immunotherapy84
Control of cell penetration enhancer shielding and endosomal escape-kinetics crucial for efficient and biocompatible siRNA delivery83
Inside Front Cover83
Outside Back Cover81
A redox-responsive nanosystem to suppress chemoresistant lung cancer through targeting STAT381
A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine80
High-definition electroporation: Precise and efficient transfection on a microelectrode array79
Content list including Graphcal Abstracts78
Outside Front Cover78
Acetazolamide-eluting biodegradable tubular stent prevents pancreaticojejunal anastomotic leakage78
Root cause determination of intraperitoneal catheter obstructions: Insulin amyloid aggregates vs foreign body reaction77
Inside Back Cover77
The pharmacokinetics of PEGylated liposomal doxorubicin are not significantly affected by sex in rats or humans, but may be affected by immune dysfunction77
Inside Front Cover77
Outside Front Cover75
Oral mucosal vaccination using integrated fiber microneedles75
Inside Back Cover74
Inside Front Cover74
Outside Front Cover73
An engineered dual function peptide to repair fractured bones71
Outside Back Cover70
Integrative approaches to enhance adeno-associated viral gene delivery70
Inside Front Cover70
Editorial Board69
Inside Back Cover69
Inside Back Cover69
Editorial Board69
Inside Front Cover68
Content list including Graphcal Abstracts68
Content list including Graphcal Abstracts68
Outside Back Cover67
Outside Back Cover66
Inside Back Cover66
Nano-trapping CXCL13 reduces regulatory B cells in tumor microenvironment and inhibits tumor growth66
Editorial Board66
Outside Back Cover66
Reducing off-target drug accumulation by exploiting a type-III interferon response65
NIR-triggered ligand-presenting nanocarriers for enhancing synergistic photothermal-chemotherapy65
Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models65
Targeting therapy for prostate cancer by pharmaceutical and clinical pharmaceutical strategies65
BBB-crossing adeno-associated virus vector: An excellent gene delivery tool for CNS disease treatment64
Translation of focused ultrasound for blood-brain barrier opening in glioma64
PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats64
Affibody-mediated controlled release of fibroblast growth factor 264
Computational modeling of corneal and scleral collagen photocrosslinking63
Development of an inhalable antiviral powder formulation against respiratory syncytial virus63
Cancer immunotherapy from biology to nanomedicine63
Magnetic resonance imaging of pancreatic islets using tissue–adhesive particles containing iron oxide nanoparticles63
Complement opsonization of nanoparticles: Differences between humans and preclinical species63
Dual mechanistic TRAIL nanocarrier based on PEGylated heparin taurocholate and protamine which exerts both pro-apoptotic and anti-angiogenic effects62
An engineered nanoplatform cascade to relieve extracellular acidity and enhance resistance-free chemotherapy62
Combinatorial physical methods for cellular therapy: Towards the future of cellular analysis?62
Nanoparticle-based delivery strategies of multifaceted immunomodulatory RNA for cancer immunotherapy62
Lipid nanoparticles to silence androgen receptor variants for prostate cancer therapy62
Role of circular RNA and its delivery strategies to cancer – An overview61
Hybrid nanopotentiators with dual cascade amplification for glioma combined interventional therapy61
Polymeric cGAMP microparticles affect the immunogenicity of a broadly active influenza mRNA lipid nanoparticle vaccine61
Ionizable nanoemulsions for RNA delivery into the central nervous system – importance of diffusivity61
Inside Back Cover61
In-situ-formed immunotherapeutic and hemostatic dual drug-loaded nanohydrogel for preventing postoperative recurrence of hepatocellular carcinoma61
Outside Back Cover61
Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy60
Triggered release from thermosensitive liposomes improves tumor targeting of vinorelbine60
Down-regulation of TNF-α via macrophage-targeted RNAi system for the treatment of acute inflammatory sepsis60
Accelerated blood clearance of PEGylated nanoparticles induced by PEG-based pharmaceutical excipients60
Liposomal encapsulation of trans-crocetin enhances oxygenation in patients with COVID-19-related ARDS receiving mechanical ventilation60
Pollens in therapeutic/diagnostic systems and immune system targeting60
The right Timing, right combination, right sequence, and right delivery for Cancer immunotherapy60
Effects of carbon-based nanomaterials on vascular endothelia under physiological and pathological conditions: interactions, mechanisms and potential therapeutic applications60
Formulation and efficacy of ECO/pRHO-ABCA4-SV40 nanoparticles for nonviral gene therapy of Stargardt disease in a mouse model59
CCL2 chemokine inhibition primes the tumor vasculature for improved nanomedicine delivery and efficacy59
An injectable biomimetic hydrogel adapting brain tissue mechanical strength for postoperative treatment of glioblastoma without anti-tumor drugs participation59
Impact of interferon-γ on the target cell tropism of nanoparticles58
Rational design of a poly-L-glutamic acid-based combination conjugate for hormone-responsive breast cancer treatment58
Studying the stability of polymer nanoparticles by size exclusion chromatography of radioactive polymers58
Inside Front Cover58
Remotely controlled drug release in deep brain regions of non-human primates58
Piperine loaded metal organic frameworks reverse doxorubicin induced chemobrain in adult zebrafish58
LNP-mRNA vaccine prevents type 1 diabetes in non-obese diabetes mice57
Wearable nitric oxide-releasing antibacterial insert for preventing device-associated infections57
CXCR4-targeted nitric oxide nanoparticles deliver PD-L1 siRNA for immunotherapy against glioblastoma56
Advance cardiac nanomedicine by targeting the pathophysiological characteristics of heart failure56
Intravitreal CendR peptides target laser-induced choroidal neovascularization sites in mice56
Enhanced browning of adipose tissue by mirabegron-microspheres56
Comprehensive analysis of the influence of physicochemical properties and tumor-associated environments on liposome intratumoral penetration55
A carrier-free anti-inflammatory platinum (II) self-delivered nanoprodrug for enhanced breast cancer therapy55
Fully armed photodynamic therapy with spear and shear for topical deep hypertrophic scar treatment55
Transdermal delivery of Fn14 siRNA using a novel composite ionic liquid for treatment of psoriasis-like skin lesions55
“Click” amphotericin B in prodrug nanoformulations for enhanced systemic fungemia treatment55
Mapping in vivo microclimate pH distribution in exenatide-encapsulated PLGA microspheres55
Engineered upconversion nanocarriers for synergistic breast cancer imaging and therapy: Current state of art54
Mechanisms of uptake and transport of particulate formulations in the small intestine54
Screening of dual chemo-photothermal cellular nanotherapies in organotypic breast cancer 3D spheroids54
Inside Front Cover54
Self-activated arsenic manganite nanohybrids for visible and synergistic thermo/immuno-arsenotherapy53
Proton-mediated burst of dual-drug loaded liposomes for biofilm dispersal and bacterial killing53
Focused ultrasound enhances transgene expression of intranasal hGDNF DNA nanoparticles in the sonicated brain regions53
Mucoadhesive film for oral delivery of vaccines for protection of the respiratory tract53
Polycation fluorination improves intraperitoneal siRNA delivery in metastatic pancreatic cancer53
Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice52
Outside Front Cover52
Poly(phenylalanine) and poly(3,4-dihydroxy-L-phenylalanine): Promising biomedical materials for building stimuli-responsive nanocarriers52
Enhancing pulmonary delivery and immunomodulation of respiratory diseases through virus-mimicking nanoparticles52
Nanobiotechnology-assisted therapies to manage brain cancer in personalized manner52
Controlling release from encapsulated drug-loaded devices: insights from modeling the dissolution front propagation52
Spatiotemporal controlled released hydrogels for multi-system regulated bone regeneration52
Alendronate-functionalized porous nano-crystalsomes mitigate osteolysis and consequent inhibition of tumor growth in a tibia-induced metastasis model52
In vivo blockade of mononuclear phagocyte system with solid nanoparticles: Efficiency and affecting factors51
Targeted drug delivery system inspired by macropinocytosis51
Biodistribution of surfactant-free poly(lactic-acid) nanoparticles and uptake by endothelial cells and phagocytes in zebrafish: Evidence for endothelium to macrophage transfer.51
Recyclable cell-surface chemical tags for repetitive cancer targeting51
Tagged extracellular vesicles with the RBD of the viral spike protein for delivery of antiviral agents against SARS-COV-2 infection51
A preliminary study of the innate immune memory of Kupffer cells induced by PEGylated nanoemulsions51
Inhibition of IL-1β release from macrophages targeted with necrosulfonamide-loaded porous nanoparticles50
Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy50
Development of a thermostable oxytocin microneedle patch50
Multicyclic topology-enhanced anticancer drug delivery50
Delivery of self-replicating messenger RNA into the brain for the treatment of ischemic stroke50
DMPC/Chol liposomal copper CX5461 is therapeutically superior to a DSPC/Chol formulation50
Hyperthermia-induced doxorubicin delivery from thermosensitive liposomes via MR-HIFU in a pig model50
In vivo self-assembled small RNA targets H19 lncRNA for the treatment of colorectal cancer49
Not only in silico drug discovery: Molecular modeling towards in silico drug delivery formulations49
Bortezomib prodrug catalytic nanoreactor for chemo/chemodynamic therapy and macrophage re-education49
A mannosylated polymer with endosomal release properties for peptide antigen delivery49
PEG2000-PLA-based nanoscale polymeric micelles reduce paclitaxel-related toxicity in beagle dogs49
Protein-induced metamorphosis of unilamellar lipid vesicles to multilamellar hybrid vesicles49
Immune cell-derived exosomes as promising tools for cancer therapy49
Physical and chemical advances of synthetic delivery vehicles to enhance mRNA vaccine efficacy49
Metal-organic framework-based dual function nanosystems for aluminum detoxification and plant growth in acidic soil48
Hypoxia-responsive liposome enhances intracellular delivery of photosensitizer for effective photodynamic therapy48
Poly(vinyl alcohol) potentiating an inert d-amino acid-based drug for boron neutron capture therapy48
Self-healing adhesive hydrogels for sustained ozone release: Enhanced antibacterial properties and improved wound healing48
Corrigendum to “Gold core@CeO2 halfshell Janus nanocomposites catalyze targeted sulfate radical for periodontitis therapy” [Journal of Controlled Release 370 (2024) 600–613]48
Oxygen-boosted fluorinated prodrug hybrid nanoassemblies for bidirectional amplification of breast cancer ferroptosis48
Nanomaterials applied in wound healing: Mechanisms, limitations and perspectives48
Synergistic in vivo anticancer effects of 1,7-heptanediol and doxorubicin co-loadedliposomes in highly aggressive breast cancer48
Nanoparticulate drug combination inhibits DNA damage repair and PD-L1 expression in BRCA-mutant and wild type triple-negative breast cancer48
Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity48
Dual-responsive nanoparticles for enhanced drug delivery in breast Cancer chemotherapy48
Exosomes: Large-scale production, isolation, drug loading efficiency, and biodistribution and uptake47
Thermoresponsive polymeric dexamethasone prodrug for arthritis pain47
Preparation and application of pH-responsive drug delivery systems47
Recent advances in lipid-engineered multifunctional nanophytomedicines for cancer targeting47
Polymeric micelles in cancer therapy: State of the art46
Delivery of mRNA for regulating functions of immune cells46
Electrospraying as a novel method of particle engineering for drug delivery vehicles46
Ultrasound-sensitive nanodroplets achieve targeted neuromodulation46
Escaping the endosome: assessing cellular trafficking mechanisms of non-viral vehicles46
ImmunoPET-informed sequence for focused ultrasound-targeted mCD47 blockade controls glioma46
Bladder cancer selective chemotherapy with potent NQO1 substrate co-loaded prodrug nanoparticles46
Exosome-based photoacoustic imaging guided photodynamic and immunotherapy for the treatment of pancreatic cancer46
Acyl and oligo(lactic acid) prodrugs for PEG-b-PLA and PEG-b-PCL nano-assemblies for injection46
Methodological needs in the quality and safety characterisation of nanotechnology-based health products: Priorities for method development and standardisation45
Emerging nanotechnological approaches to regulating tumor vasculature for cancer therapy45
Advances in controlled release hormonal technologies for contraception: A review of existing devices, underlying mechanisms, and future directions45
Redox modulation with a perfluorocarbon nanoparticle to reverse Treg-mediated immunosuppression and enhance anti-tumor immunity45
The application of immune checkpoint blockade in breast cancer and the emerging role of nanoparticle45
An injectable PEG hydrogel controlling neurotrophin-3 release by affinity peptides45
Spleen-targeted delivery systems and strategies for spleen-related diseases45
Matrix metalloproteinase-1 decorated polymersomes, a surface-active extracellular matrix therapeutic, potentiates collagen degradation and attenuates early liver fibrosis45
Hydrogel-forming microarray patches with solid dispersion reservoirs for transdermal long-acting microdepot delivery of a hydrophobic drug45
Efficient ultrasound-mediated drug delivery to orthotopic liver tumors – Direct comparison of doxorubicin-loaded nanobubbles and microbubbles44
On-demand release of the small-molecule TrkB agonist improves neuron-Schwann cell interactions44
“CO in a pill”: Towards oral delivery of carbon monoxide for therapeutic applications44
Dual cancer stem cell manipulation to enhance phototherapy against tumor progression and metastasis44
Nanodrugs mediate TAMs-related arginine metabolism interference to boost photodynamic immunotherapy43
Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis43
Adaptable peptide-based therapeutics modulating tumor microenvironment for combinatorial radio-immunotherapy43
Cancer therapy by antibody-targeted Cerenkov light and metabolism-selective photosensitization43
Hydroxyapatite-binding albumin nanoclusters for enhancing bone tumor chemotherapy43
Perspective on drug delivery in 205043
Shape-directed drug release and transport of erythrocyte-like nanodisks augment chemotherapy43
Enhanced BBB and BBTB penetration and improved anti-glioma behavior of Bortezomib through dual-targeting nanostructured lipid carriers43
Nanoghosts: Mesenchymal Stem cells derived nanoparticles as a unique approach for cartilage regeneration43
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