OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Controlled Release is 89. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Inside Back Cover	630
Outside Back Cover	559
Outside Back Cover	441
Collagenase-modified polydopamine nanoparticles for safe and effective vitreolysis	419
The osteogenic and angiogenic potential of microRNA-26a delivered via a non-viral delivery peptide for bone repair	415
Impact of interferon-γ on the target cell tropism of nanoparticles	363
Autophagy-modulating biomembrane nanostructures: A robust anticancer weapon by modulating the inner and outer cancer environment	328
Boronate-crosslinked hydrogel enables localized chemoimmunotherapy to remodel the immune microenvironment in triple-negative breast cancer	301
Predicting human subcutaneous bioavailability of monoclonal antibodies using an open flow microperfusion porcine model	283
In-situ-formed immunotherapeutic and hemostatic dual drug-loaded nanohydrogel for preventing postoperative recurrence of hepatocellular carcinoma	273
Cavitation-assisted sonothrombolysis by asymmetrical nanostars for accelerated thrombolysis	269
Dasatinib and erianin co-loaded ion-responsive in-situ hydrogel for effective treatment of corneal neovascularization	252
A superoxide anion-responsive persulfide prodrug for remedying dry eye disease	241
Corrigendum to “Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch” [Journal of Controlled Release 372 (2024) 304–317]	210
Surface-engineered mesenchymal stem cell for refractory asthma therapy: Reversing airway remodeling	199
An engineered dual function peptide to repair fractured bones	197
Outside Back Cover	197
Outside Front Cover: Yisheng Peng et al	196
Combination of multivalent DR5 receptor clustering agonists and histone deacetylase inhibitors for treatment of colon cancer	196
Transdermal carbon monoxide delivery	196
Hybrid prodrug nanoassembly for hypoxia-triggered immunogenic chemotherapy and immune modulation	188
Thiourea-modified poly(l-lysine) carriers with multiple hydrogen bonding interactions for safe and robust mRNA vaccine therapy	183
Enhanced browning of adipose tissue by mirabegron-microspheres	174
Vascular endothelial cell-targeted mRNA delivery via synthetic lipid nanoparticles for venous thrombosis prevention	173
Combinatorial physical methods for cellular therapy: Towards the future of cellular analysis?	169

Delivery of DNA octahedra enhanced by focused ultrasound with microbubbles for glioma therapy	165
Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity	164
Oral mucosal vaccination using integrated fiber microneedles	162
Engineered exosomes with enhanced stability and delivery efficiency for glioblastoma therapy	162
Customization of protein corona to reprogram cancer nanomedicines: Mechanistic insights and therapeutic implications	162
Hypoxia-responsive oncolytic conjugate triggers type-II immunogenic cell death for enhanced photodynamic immunotherapy	146
Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis	145
Oxygen-boosted fluorinated prodrug hybrid nanoassemblies for bidirectional amplification of breast cancer ferroptosis	144
Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma?	142
Single-cell RNA transcriptome landscape of murine liver following systemic administration of mesoporous silica nanoparticles	139
Dendritic cell derived exosomes loaded neoantigens for personalized cancer immunotherapies	138
Biomimetic reactive oxygen/nitrogen nanoscavengers inhibit “ferroptosis storm” and modulate immune targeting for acute kidney injury	137
Ferroptosis boosted oral cancer photodynamic therapy by carrier-free Sorafenib-Ce6 self-assembly nanoparticles	134
The inflammatory bowel disease and gut microbiome are restored by employing metformin-loaded alginate-shelled microcapsules	132
Orthogonal upconversion nanocarriers for combined photodynamic therapy and precisely triggered gene silencing in combating keloids	130
Macrophage-targeting nano-formulated bicalutamide alleviates colitis by inducing MAP3K1-mediated degradation of NLRP3	130
Prediction of drug capturing by lipid emulsions in vivo for the treatment of a drug overdose	129
Enhancing gene transfection of poly(β-amino ester)s through modulation of amphiphilicity and chain sequence	129
ZIF-8-modified hydrogel sequentially delivers angiogenic and osteogenic growth factors to accelerate vascularized bone regeneration	126
Injectable nanocomposite hydrogel with cascade drug release for treatment of uveal melanoma	124
In vivo delivery of antioxidant enzymes with multi-functionalized lipid nanoparticles for sepsis therapy	123
The pharmacokinetic profile of mitomycin C released from an injectable supramolecular hydrogel in a rodent model	122
Pickering emulsion-guided monomeric delivery of monophosphoryl lipid A for enhanced vaccination	121
Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice	120
Hybrid nanopotentiators with dual cascade amplification for glioma combined interventional therapy	120
Nanoparticle-mediated thermal Cancer therapies: Strategies to improve clinical translatability	120
Optimized bacterial delivery approaches for precision immunotherapy in breast cancer models	119
Full-cycle study on developing a novel structured micromixer and evaluating the nanoparticle products as mRNA delivery carriers	119
Nanoparticle-based methionine and AICAR delivery elicits a robust antitumor immune response	119
An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability	117
Self-assembly hydrogels of therapeutic agents for local drug delivery	116
Tumor permeable self-delivery nanodrug targeting mitochondria for enhanced chemotherapy	116
Conditioned media-integrated microneedles for hair regeneration through perifollicular angiogenesis	113
Accelerated blood clearance of PEGylated nanoparticles induced by PEG-based pharmaceutical excipients	113
Alendronate-functionalized polymeric micelles target icaritin to bone for mitigating osteoporosis in a rat model	110
Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis	107
Ultrasound-activatable nanovaccines amplify dual-modal ROS for cancer sono-immunotherapy	107
A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine	106
Dynamic versus static testing and in vivo mechanical performance of poly(glycolide-trimethylene carbonate-ε-caprolactone) delayed release implants	105
Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy	105
Intraneural delivery of CBD3A6K-RhB via PEG-PLGA nanoparticles for neuropathic pain therapy	104
Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors	104
Identification of functional biomarkers for personalized nanomedicine in advanced breast cancer in vitro models	104
Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy	104
Biomaterial scaffolds for therapeutic immune cell engineering and delivery	103
Modified montmorillonite armed probiotics with enhanced on-site mucus-depleted intestinal colonization and H2S scavenging for colitis treatment	103
Coordinated modulation of glucose metabolism and immunity via metal-drug nanovesicles for hepatocellular carcinoma therapy	100
Outside Front Cover	100
Intraperitoneal drug delivery systems for peritoneal carcinomatosis: Bridging the gap between research and clinical implementation	100
Designing and modeling nanomedicines towards image-guided drug delivery in hematological malignancies	99

Multifunctional delivery strategies and nanoplatforms of SN-38 in cancer therapeutics	99
Lanthanide nanocrystals-based direct triple-state energy converters for mitophagy and ferroptosis-induced antitumor immunoreaction	98
Functional nanoplatform for modulating cellular forces to enhance antitumor immunity via mechanotransduction	98
Metal-phenolic network-based polymeric nanocarriers facilitating antibody cytoplasmic delivery and anti-tumor effects to orthotopic breast tumors	98
Outside Front Cover - K. Keiichiro et al	97
Targeted and quantitatively modeled biologic delivery via dual-functional probiotic yeast in inflammatory bowel disease	95
Inside Front Cover - J. Xiaohong et al.	95
The colon targeting efficacies of mesalazine medications and their impacts on the gut microbiome	95
MSC-derived extracellular vesicles as nanotherapeutics for promoting aged liver regeneration	94
Melittin-incorporated nanomedicines for enhanced cancer immunotherapy	93
Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications	91
A next-generation STING agonist MSA-2: From mechanism to application	91
Extracellular vesicles for renal therapeutics: State of the art and future perspective	90
Multifunctional nanoparticles potentiate in-situ tumor vaccines via reversing insufficient Photothermal therapy by disrupting tumor vasculature	90
Dual-stimulus phototherapeutic nanogel for triggering pyroptosis to promote cancer immunotherapy	89
Targosomes: Anti-HER2 PLGA nanocarriers for bioimaging, chemotherapy and local photothermal treatment of tumors and remote metastases	89
Bioorthogonal conjugation and responsive nanocoating of probiotics for inflammatory bowel disease	89