OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Controlled Release is 93. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Inside Back Cover	597
Outside Back Cover	476
Impact of interferon-γ on the target cell tropism of nanoparticles	442
Cavitation-assisted sonothrombolysis by asymmetrical nanostars for accelerated thrombolysis	441
Corrigendum to “Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch” [Journal of Controlled Release 372 (2024) 304–317]	375
Outside Back Cover	349
Outside Front Cover: Yisheng Peng et al	324
Transdermal carbon monoxide delivery	306
Alendronate-functionalized polymeric micelles target icaritin to bone for mitigating osteoporosis in a rat model	300
Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors	283
Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy	271
Enhanced browning of adipose tissue by mirabegron-microspheres	263
Single-cell RNA transcriptome landscape of murine liver following systemic administration of mesoporous silica nanoparticles	213
In vivo delivery of antioxidant enzymes with multi-functionalized lipid nanoparticles for sepsis therapy	212
Enhancing gene transfection of poly(β-amino ester)s through modulation of amphiphilicity and chain sequence	212
The pharmacokinetic profile of mitomycin C released from an injectable supramolecular hydrogel in a rodent model	209
Full-cycle study on developing a novel structured micromixer and evaluating the nanoparticle products as mRNA delivery carriers	208
An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability	206
Mitochondria-targeted hybrid nanovesicles trigger immunogenic cell death and remodel tumor neutrophils for enhanced colorectal cancer immunotherapy	205
Site-specific engineering of S-Te-S bridged nano-prodrug: A dual equilibrium strategy for enhanced antitumor efficacy and safety of paclitaxel	204
Hypoxia-responsive oncolytic conjugate triggers type-II immunogenic cell death for enhanced photodynamic immunotherapy	203
Vascular endothelial cell-targeted mRNA delivery via synthetic lipid nanoparticles for venous thrombosis prevention	201
Lanthanide nanocrystals-based direct triple-state energy converters for mitophagy and ferroptosis-induced antitumor immunoreaction	192
Macrophage-targeting nano-formulated bicalutamide alleviates colitis by inducing MAP3K1-mediated degradation of NLRP3	186
Collagenase-modified polydopamine nanoparticles for safe and effective vitreolysis	181

Outside Front Cover	178
Outside Front Cover - K. Keiichiro et al	173
Inside Front Cover - J. Xiaohong et al.	169
Targeted and quantitatively modeled biologic delivery via dual-functional probiotic yeast in inflammatory bowel disease	167
Conditioned media-integrated microneedles for hair regeneration through perifollicular angiogenesis	159
Multifunctional nanoparticles potentiate in-situ tumor vaccines via reversing insufficient Photothermal therapy by disrupting tumor vasculature	158
Identification of functional biomarkers for personalized nanomedicine in advanced breast cancer in vitro models	158
Targosomes: Anti-HER2 PLGA nanocarriers for bioimaging, chemotherapy and local photothermal treatment of tumors and remote metastases	154
Self-sacrificing templated-derived chitosan microcapsules for targeted drug delivery in thrombolytic therapy	152
Oscillation-generating micromixing (FDmiX) – a new method for manufacturing of mRNA-lipid nanoparticles with scalable high-throughput production	149
Content list including Graphcal Abstracts	147
Predicting human subcutaneous bioavailability of monoclonal antibodies using an open flow microperfusion porcine model	146
Losartan primes pancreatic tumors for effective exosome-biomimetic chemo-immunotherapy	146
Boronate-crosslinked hydrogel enables localized chemoimmunotherapy to remodel the immune microenvironment in triple-negative breast cancer	142
Polymer selection in amorphous solid dispersions: From stabilization mechanisms to marketed drug products	141
Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis	139
Intraneural delivery of CBD3A6K-RhB via PEG-PLGA nanoparticles for neuropathic pain therapy	136
Buforin IIb and bilirubin co-loaded CeO₂nanoparticles mitigate sepsis-related encephalopathy via synergistic anti-inflammation and neuroprotection	133
Dual-stimulus phototherapeutic nanogel for triggering pyroptosis to promote cancer immunotherapy	133
Oxygen-boosted fluorinated prodrug hybrid nanoassemblies for bidirectional amplification of breast cancer ferroptosis	129
Nanogel-controlled delivery of caerin peptides enables sustained intratumoural retention and immunometabolic reprogramming	129
Nanobubble based sonobiopsy reveals circulating protein signatures of BBB opening in healthy and glioblastoma-bearing mice	129
Biomaterial scaffolds for therapeutic immune cell engineering and delivery	129
Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma?	127
Multifunctional amino acid-based nanoparticles for sequential drug delivery to overcome multidrug resistant cancer	127
Combination of multivalent DR5 receptor clustering agonists and histone deacetylase inhibitors for treatment of colon cancer	126
Dasatinib and erianin co-loaded ion-responsive in-situ hydrogel for effective treatment of corneal neovascularization	125
Thiourea-modified poly(l-lysine) carriers with multiple hydrogen bonding interactions for safe and robust mRNA vaccine therapy	125
Multifunctional delivery strategies and nanoplatforms of SN-38 in cancer therapeutics	120
Dynamic versus static testing and in vivo mechanical performance of poly(glycolide-trimethylene carbonate-ε-caprolactone) delayed release implants	120
Orthogonal upconversion nanocarriers for combined photodynamic therapy and precisely triggered gene silencing in combating keloids	119
Nanoparticle-mediated thermal Cancer therapies: Strategies to improve clinical translatability	118
In-situ-formed immunotherapeutic and hemostatic dual drug-loaded nanohydrogel for preventing postoperative recurrence of hepatocellular carcinoma	118
Customization of protein corona to reprogram cancer nanomedicines: Mechanistic insights and therapeutic implications	116
Autophagy-modulating biomembrane nanostructures: A robust anticancer weapon by modulating the inner and outer cancer environment	116
Hydrogel-forming microarray patches with solid dispersion reservoirs for transdermal long-acting microdepot delivery of a hydrophobic drug	114
Metal-phenolic network-based polymeric nanocarriers facilitating antibody cytoplasmic delivery and anti-tumor effects to orthotopic breast tumors	113
Accelerated blood clearance of PEGylated nanoparticles induced by PEG-based pharmaceutical excipients	112
Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity	112
IFN-γ-primed MSC extracellular vesicles attenuate rheumatoid arthritis via PD-L1-driven T-cell suppression and bone preservation	111
A superoxide anion-responsive persulfide prodrug for remedying dry eye disease	111
Ultrasound-activatable nanovaccines amplify dual-modal ROS for cancer sono-immunotherapy	111
Engineered exosomes with enhanced stability and delivery efficiency for glioblastoma therapy	111
Extracellular vesicles for renal therapeutics: State of the art and future perspective	111
Combinatorial physical methods for cellular therapy: Towards the future of cellular analysis?	110
Healing with precision: A multi-functional hydrogel-bioactive glass dressing boosts infected wound recovery and enhances neurogenesis in the wound bed	110
Tumor permeable self-delivery nanodrug targeting mitochondria for enhanced chemotherapy	109
Delivery of DNA octahedra enhanced by focused ultrasound with microbubbles for glioma therapy	108
Hybrid nanopotentiators with dual cascade amplification for glioma combined interventional therapy	107
Nanoparticle-based methionine and AICAR delivery elicits a robust antitumor immune response	105

Surface-engineered mesenchymal stem cell for refractory asthma therapy: Reversing airway remodeling	104
An engineered dual function peptide to repair fractured bones	104
Oral mucosal vaccination using integrated fiber microneedles	103
The osteogenic and angiogenic potential of microRNA-26a delivered via a non-viral delivery peptide for bone repair	101
mRNA therapeutics: Molecular mechanisms, delivery platforms, regulatory frameworks, and equitable global access	100
Designing and modeling nanomedicines towards image-guided drug delivery in hematological malignancies	100
Bioorthogonal conjugation and responsive nanocoating of probiotics for inflammatory bowel disease	98
Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice	98
A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine	98
Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications	97
Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy	97
The inflammatory bowel disease and gut microbiome are restored by employing metformin-loaded alginate-shelled microcapsules	96
Injectable nanocomposite hydrogel with cascade drug release for treatment of uveal melanoma	96
Modified montmorillonite armed probiotics with enhanced on-site mucus-depleted intestinal colonization and H2S scavenging for colitis treatment	95
In vivo self-assembled small RNA targets H19 lncRNA for the treatment of colorectal cancer	95
Coordinated modulation of glucose metabolism and immunity via metal-drug nanovesicles for hepatocellular carcinoma therapy	93
Pickering emulsion-guided monomeric delivery of monophosphoryl lipid A for enhanced vaccination	93
Corrigendum to “The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs” [J. Control. Release 345 (2022) 819–831]	93
Melittin-incorporated nanomedicines for enhanced cancer immunotherapy	93
Optimized bacterial delivery approaches for precision immunotherapy in breast cancer models	93