OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Controlled Release is 84. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes	525
Prediction of drug capturing by lipid emulsions in vivo for the treatment of a drug overdose	363
Outside Back Cover	362
Inside Back Cover	317
Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy	267
In vivo self-assembled small RNA targets H19 lncRNA for the treatment of colorectal cancer	265
Full-cycle study on developing a novel structured micromixer and evaluating the nanoparticle products as mRNA delivery carriers	251
Alendronate-functionalized polymeric micelles target icaritin to bone for mitigating osteoporosis in a rat model	246
Thermoresponsive polymeric dexamethasone prodrug for arthritis pain	245
Integrative approaches to enhance adeno-associated viral gene delivery	237
Pickering emulsion-guided monomeric delivery of monophosphoryl lipid A for enhanced vaccination	236
Inside Back Cover	234
Corrigendum to “Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch” [Journal of Controlled Release 372 (2024) 304–317]	218
Oxygen-boosted fluorinated prodrug hybrid nanoassemblies for bidirectional amplification of breast cancer ferroptosis	215
Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity	197
An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability	193
Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors	180
In-situ-formed immunotherapeutic and hemostatic dual drug-loaded nanohydrogel for preventing postoperative recurrence of hepatocellular carcinoma	178
Outside Back Cover	172
A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine	169
Macrophage-targeting nano-formulated bicalutamide alleviates colitis by inducing MAP3K1-mediated degradation of NLRP3	167
Outside Front Cover: Yisheng Peng et al	162
Impact of interferon-γ on the target cell tropism of nanoparticles	160
Dual-stimulus phototherapeutic nanogel for triggering pyroptosis to promote cancer immunotherapy	159
The osteogenic and angiogenic potential of microRNA-26a delivered via a non-viral delivery peptide for bone repair	159

Combinatorial physical methods for cellular therapy: Towards the future of cellular analysis?	156
White paper: Understanding, informing and defining the regulatory science of microneedle-based dosage forms that are applied to the skin	151
Multifunctional nanoparticles potentiate in-situ tumor vaccines via reversing insufficient Photothermal therapy by disrupting tumor vasculature	151
Mechanisms of uptake and transport of particulate formulations in the small intestine	145
Tumor permeable self-delivery nanodrug targeting mitochondria for enhanced chemotherapy	143
Extracellular vesicles for renal therapeutics: State of the art and future perspective	141
Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis	140
Dynamic versus static testing and in vivo mechanical performance of poly(glycolide-trimethylene carbonate-ε-caprolactone) delayed release implants	136
Targosomes: Anti-HER2 PLGA nanocarriers for bioimaging, chemotherapy and local photothermal treatment of tumors and remote metastases	136
Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy	131
Single-cell RNA transcriptome landscape of murine liver following systemic administration of mesoporous silica nanoparticles	129
Outside Back Cover	127
A next-generation STING agonist MSA-2: From mechanism to application	126
Hybrid nanopotentiators with dual cascade amplification for glioma combined interventional therapy	124
Combination of multivalent DR5 receptor clustering agonists and histone deacetylase inhibitors for treatment of colon cancer	122
Bioorthogonal conjugation and responsive nanocoating of probiotics for inflammatory bowel disease	121
Oral mucosal vaccination using integrated fiber microneedles	121
Autophagy-modulating biomembrane nanostructures: A robust anticancer weapon by modulating the inner and outer cancer environment	121
Identification of functional biomarkers for personalized nanomedicine in advanced breast cancer in vitro models	119
Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma?	117
Tagged extracellular vesicles with the RBD of the viral spike protein for delivery of antiviral agents against SARS-COV-2 infection	117
An engineered dual function peptide to repair fractured bones	116
Nanomaterials applied in wound healing: Mechanisms, limitations and perspectives	114
Down-regulation of TNF-α via macrophage-targeted RNAi system for the treatment of acute inflammatory sepsis	114
Enhanced browning of adipose tissue by mirabegron-microspheres	114
The colon targeting efficacies of mesalazine medications and their impacts on the gut microbiome	113
Advance cardiac nanomedicine by targeting the pathophysiological characteristics of heart failure	113
Nano-trapping CXCL13 reduces regulatory B cells in tumor microenvironment and inhibits tumor growth	113
Conditioned media-integrated microneedles for hair regeneration through perifollicular angiogenesis	112
Dasatinib and erianin co-loaded ion-responsive in-situ hydrogel for effective treatment of corneal neovascularization	111
Nanoghosts: Mesenchymal Stem cells derived nanoparticles as a unique approach for cartilage regeneration	109
Enhancing gene transfection of poly(β-amino ester)s through modulation of amphiphilicity and chain sequence	108
Adaptable peptide-based therapeutics modulating tumor microenvironment for combinatorial radio-immunotherapy	107
Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications	106
Methodological needs in the quality and safety characterisation of nanotechnology-based health products: Priorities for method development and standardisation	102
Delivery of DNA octahedra enhanced by focused ultrasound with microbubbles for glioma therapy	101
Injectable nanocomposite hydrogel with cascade drug release for treatment of uveal melanoma	100
ZIF-8-modified hydrogel sequentially delivers angiogenic and osteogenic growth factors to accelerate vascularized bone regeneration	100
Engineered exosomes with enhanced stability and delivery efficiency for glioblastoma therapy	100
Micellar paclitaxel boosts ICD and chemo-immunotherapy of metastatic triple negative breast cancer	96
Development of a thermostable oxytocin microneedle patch	96
Transdermal carbon monoxide delivery	95
Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice	95
A smart cauliflower-like carrier for astaxanthin delivery to relieve colon inflammation	94
Hydrogel-forming microarray patches with solid dispersion reservoirs for transdermal long-acting microdepot delivery of a hydrophobic drug	93
Intraperitoneal drug delivery systems for peritoneal carcinomatosis: Bridging the gap between research and clinical implementation	91
Ferroptosis boosted oral cancer photodynamic therapy by carrier-free Sorafenib-Ce6 self-assembly nanoparticles	91
Modified montmorillonite armed probiotics with enhanced on-site mucus-depleted intestinal colonization and H2S scavenging for colitis treatment	91
Orthogonal upconversion nanocarriers for combined photodynamic therapy and precisely triggered gene silencing in combating keloids	91
The inflammatory bowel disease and gut microbiome are restored by employing metformin-loaded alginate-shelled microcapsules	91

Complement opsonization of nanoparticles: Differences between humans and preclinical species	89
Surface-engineered mesenchymal stem cell for refractory asthma therapy: Reversing airway remodeling	88
Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis	87
Cavitation-assisted sonothrombolysis by asymmetrical nanostars for accelerated thrombolysis	87
Melittin-incorporated nanomedicines for enhanced cancer immunotherapy	86
Self-assembly hydrogels of therapeutic agents for local drug delivery	85
Hybrid prodrug nanoassembly for hypoxia-triggered immunogenic chemotherapy and immune modulation	85
Biomimetic reactive oxygen/nitrogen nanoscavengers inhibit “ferroptosis storm” and modulate immune targeting for acute kidney injury	84
MSC-derived extracellular vesicles as nanotherapeutics for promoting aged liver regeneration	84
Functional nanoplatform for modulating cellular forces to enhance antitumor immunity via mechanotransduction	84
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs	84
Mechanism exploration of intestinal mucus penetration of nano-Se: regulated by polysaccharides with different functional groups and molecular weights	84