OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Controlled Release is 93. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Inside Back Cover	606
Outside Back Cover	542
Outside Back Cover	421
Impact of interferon-γ on the target cell tropism of nanoparticles	406
Oscillation-generating micromixing (FDmiX) – a new method for manufacturing of mRNA-lipid nanoparticles with scalable high-throughput production	405
Healing with precision: A multi-functional hydrogel-bioactive glass dressing boosts infected wound recovery and enhances neurogenesis in the wound bed	350
Losartan primes pancreatic tumors for effective exosome-biomimetic chemo-immunotherapy	321
Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma?	287
Dynamic versus static testing and in vivo mechanical performance of poly(glycolide-trimethylene carbonate-ε-caprolactone) delayed release implants	282
Delivery of DNA octahedra enhanced by focused ultrasound with microbubbles for glioma therapy	274
Pickering emulsion-guided monomeric delivery of monophosphoryl lipid A for enhanced vaccination	266
Melittin-incorporated nanomedicines for enhanced cancer immunotherapy	266
Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications	246
Content list including Graphcal Abstracts	244
Autophagy-modulating biomembrane nanostructures: A robust anticancer weapon by modulating the inner and outer cancer environment	233
Self-sacrificing templated-derived chitosan microcapsules for targeted drug delivery in thrombolytic therapy	228
In-situ-formed immunotherapeutic and hemostatic dual drug-loaded nanohydrogel for preventing postoperative recurrence of hepatocellular carcinoma	208
Coordinated modulation of glucose metabolism and immunity via metal-drug nanovesicles for hepatocellular carcinoma therapy	195
Boronate-crosslinked hydrogel enables localized chemoimmunotherapy to remodel the immune microenvironment in triple-negative breast cancer	194
Predicting human subcutaneous bioavailability of monoclonal antibodies using an open flow microperfusion porcine model	193
Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis	191
Engineered exosomes with enhanced stability and delivery efficiency for glioblastoma therapy	191
Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis	189
A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine	179
Corrigendum to “Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch” [Journal of Controlled Release 372 (2024) 304–317]	178

The osteogenic and angiogenic potential of microRNA-26a delivered via a non-viral delivery peptide for bone repair	167
The inflammatory bowel disease and gut microbiome are restored by employing metformin-loaded alginate-shelled microcapsules	163
Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice	159
Multifunctional nanoparticles potentiate in-situ tumor vaccines via reversing insufficient Photothermal therapy by disrupting tumor vasculature	159
Extracellular vesicles for renal therapeutics: State of the art and future perspective	158
An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability	157
In vivo delivery of antioxidant enzymes with multi-functionalized lipid nanoparticles for sepsis therapy	156
Multifunctional amino acid-based nanoparticles for sequential drug delivery to overcome multidrug resistant cancer	156
Hypoxia-responsive oncolytic conjugate triggers type-II immunogenic cell death for enhanced photodynamic immunotherapy	154
Biomimetic reactive oxygen/nitrogen nanoscavengers inhibit “ferroptosis storm” and modulate immune targeting for acute kidney injury	154
Tumor permeable self-delivery nanodrug targeting mitochondria for enhanced chemotherapy	152
Injectable nanocomposite hydrogel with cascade drug release for treatment of uveal melanoma	143
Mechanism exploration of intestinal mucus penetration of nano-Se: regulated by polysaccharides with different functional groups and molecular weights	143
Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy	142
White paper: Understanding, informing and defining the regulatory science of microneedle-based dosage forms that are applied to the skin	140
Modified montmorillonite armed probiotics with enhanced on-site mucus-depleted intestinal colonization and H2S scavenging for colitis treatment	138
Ferroptosis boosted oral cancer photodynamic therapy by carrier-free Sorafenib-Ce6 self-assembly nanoparticles	134
Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy	133
Identification of functional biomarkers for personalized nanomedicine in advanced breast cancer in vitro models	133
Customization of protein corona to reprogram cancer nanomedicines: Mechanistic insights and therapeutic implications	128
Ultrasound-activatable nanovaccines amplify dual-modal ROS for cancer sono-immunotherapy	127
Biomaterial scaffolds for therapeutic immune cell engineering and delivery	127
Alendronate-functionalized polymeric micelles target icaritin to bone for mitigating osteoporosis in a rat model	126
Oral mucosal vaccination using integrated fiber microneedles	125
A next-generation STING agonist MSA-2: From mechanism to application	125
Dendritic cell derived exosomes loaded neoantigens for personalized cancer immunotherapies	122
Intraperitoneal drug delivery systems for peritoneal carcinomatosis: Bridging the gap between research and clinical implementation	120
Conditioned media-integrated microneedles for hair regeneration through perifollicular angiogenesis	120
Nanoparticle-mediated thermal Cancer therapies: Strategies to improve clinical translatability	120
Oxygen-boosted fluorinated prodrug hybrid nanoassemblies for bidirectional amplification of breast cancer ferroptosis	118
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs	117
Bioorthogonal conjugation and responsive nanocoating of probiotics for inflammatory bowel disease	116
Mitochondria-targeted hybrid nanovesicles trigger immunogenic cell death and remodel tumor neutrophils for enhanced colorectal cancer immunotherapy	116
Accelerated blood clearance of PEGylated nanoparticles induced by PEG-based pharmaceutical excipients	115
Microneedle-mediated nose-to-brain drug delivery for improved Alzheimer's disease treatment	115
ZIF-8-modified hydrogel sequentially delivers angiogenic and osteogenic growth factors to accelerate vascularized bone regeneration	115
Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors	114
Dual-stimulus phototherapeutic nanogel for triggering pyroptosis to promote cancer immunotherapy	113
Full-cycle study on developing a novel structured micromixer and evaluating the nanoparticle products as mRNA delivery carriers	113
Targosomes: Anti-HER2 PLGA nanocarriers for bioimaging, chemotherapy and local photothermal treatment of tumors and remote metastases	113
Enhancing gene transfection of poly(β-amino ester)s through modulation of amphiphilicity and chain sequence	112
Single-cell RNA transcriptome landscape of murine liver following systemic administration of mesoporous silica nanoparticles	111
Collagenase-modified polydopamine nanoparticles for safe and effective vitreolysis	107
Surface-engineered mesenchymal stem cell for refractory asthma therapy: Reversing airway remodeling	106
Macrophage-targeting nano-formulated bicalutamide alleviates colitis by inducing MAP3K1-mediated degradation of NLRP3	105
Prediction of drug capturing by lipid emulsions in vivo for the treatment of a drug overdose	105
Outside Front Cover: Yisheng Peng et al	104
Designing and modeling nanomedicines towards image-guided drug delivery in hematological malignancies	103
Orthogonal upconversion nanocarriers for combined photodynamic therapy and precisely triggered gene silencing in combating keloids	103
Cavitation-assisted sonothrombolysis by asymmetrical nanostars for accelerated thrombolysis	103

Combination of multivalent DR5 receptor clustering agonists and histone deacetylase inhibitors for treatment of colon cancer	101
Lanthanide nanocrystals-based direct triple-state energy converters for mitophagy and ferroptosis-induced antitumor immunoreaction	101
Optimized bacterial delivery approaches for precision immunotherapy in breast cancer models	100
Nanoparticle-based methionine and AICAR delivery elicits a robust antitumor immune response	100
A superoxide anion-responsive persulfide prodrug for remedying dry eye disease	100
Functional nanoplatform for modulating cellular forces to enhance antitumor immunity via mechanotransduction	99
Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity	99
Site-specific engineering of S-Te-S bridged nano-prodrug: A dual equilibrium strategy for enhanced antitumor efficacy and safety of paclitaxel	98
The pharmacokinetic profile of mitomycin C released from an injectable supramolecular hydrogel in a rodent model	98
Dasatinib and erianin co-loaded ion-responsive in-situ hydrogel for effective treatment of corneal neovascularization	98
The colon targeting efficacies of mesalazine medications and their impacts on the gut microbiome	97
Intraneural delivery of CBD3A6K-RhB via PEG-PLGA nanoparticles for neuropathic pain therapy	97
Multifunctional delivery strategies and nanoplatforms of SN-38 in cancer therapeutics	96
Metal-phenolic network-based polymeric nanocarriers facilitating antibody cytoplasmic delivery and anti-tumor effects to orthotopic breast tumors	96
Outside Front Cover	95
In vivo self-assembled small RNA targets H19 lncRNA for the treatment of colorectal cancer	94
Transdermal carbon monoxide delivery	93
Hybrid prodrug nanoassembly for hypoxia-triggered immunogenic chemotherapy and immune modulation	93