OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Controlled Release is 91. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Designing and modeling nanomedicines towards image-guided drug delivery in hematological malignancies	535
Outside Front Cover	455
Inside Back Cover	371
Corrigendum to “Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch” [Journal of Controlled Release 372 (2024) 304–317]	366
Outside Back Cover	361
Outside Back Cover	356
Integrative approaches to enhance adeno-associated viral gene delivery	352
Impact of interferon-γ on the target cell tropism of nanoparticles	306
The pharmacokinetic profile of mitomycin C released from an injectable supramolecular hydrogel in a rodent model	283
Coordinated modulation of glucose metabolism and immunity via metal-drug nanovesicles for hepatocellular carcinoma therapy	279
Collagenase-modified polydopamine nanoparticles for safe and effective vitreolysis	272
Customization of protein corona to reprogram cancer nanomedicines: Mechanistic insights and therapeutic implications	269
Mitochondria-targeted hybrid nanovesicles trigger immunogenic cell death and remodel tumor neutrophils for enhanced colorectal cancer immunotherapy	254
Multifunctional nanoparticles potentiate in-situ tumor vaccines via reversing insufficient Photothermal therapy by disrupting tumor vasculature	253
Vascular endothelial cell-targeted mRNA delivery via synthetic lipid nanoparticles for venous thrombosis prevention	246
Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy	226
Autophagy-modulating biomembrane nanostructures: A robust anticancer weapon by modulating the inner and outer cancer environment	224
Optimized bacterial delivery approaches for precision immunotherapy in breast cancer models	219
Nanoparticle-based methionine and AICAR delivery elicits a robust antitumor immune response	219
In vivo self-assembled small RNA targets H19 lncRNA for the treatment of colorectal cancer	206
Outside Front Cover: Yisheng Peng et al	206
Single-cell RNA transcriptome landscape of murine liver following systemic administration of mesoporous silica nanoparticles	206
Prediction of drug capturing by lipid emulsions in vivo for the treatment of a drug overdose	205
Outside Back Cover	197
Biomaterial scaffolds for therapeutic immune cell engineering and delivery	185

Nano-trapping CXCL13 reduces regulatory B cells in tumor microenvironment and inhibits tumor growth	175
Extracellular vesicles for renal therapeutics: State of the art and future perspective	175
Ultrasound-activatable nanovaccines amplify dual-modal ROS for cancer sono-immunotherapy	171
MSC-derived extracellular vesicles as nanotherapeutics for promoting aged liver regeneration	170
An engineered dual function peptide to repair fractured bones	170
Dynamic versus static testing and in vivo mechanical performance of poly(glycolide-trimethylene carbonate-ε-caprolactone) delayed release implants	163
An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability	157
Combination of multivalent DR5 receptor clustering agonists and histone deacetylase inhibitors for treatment of colon cancer	153
Enhanced browning of adipose tissue by mirabegron-microspheres	152
Enhancing gene transfection of poly(β-amino ester)s through modulation of amphiphilicity and chain sequence	148
A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine	145
Hypoxia-responsive oncolytic conjugate triggers type-II immunogenic cell death for enhanced photodynamic immunotherapy	145
Surface-engineered mesenchymal stem cell for refractory asthma therapy: Reversing airway remodeling	142
Predicting human subcutaneous bioavailability of monoclonal antibodies using an open flow microperfusion porcine model	138
Dasatinib and erianin co-loaded ion-responsive in-situ hydrogel for effective treatment of corneal neovascularization	137
Combinatorial physical methods for cellular therapy: Towards the future of cellular analysis?	137
Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy	135
The colon targeting efficacies of mesalazine medications and their impacts on the gut microbiome	132
Oral mucosal vaccination using integrated fiber microneedles	130
Thiourea-modified poly(l-lysine) carriers with multiple hydrogen bonding interactions for safe and robust mRNA vaccine therapy	130
Boronate-crosslinked hydrogel enables localized chemoimmunotherapy to remodel the immune microenvironment in triple-negative breast cancer	127
Tumor permeable self-delivery nanodrug targeting mitochondria for enhanced chemotherapy	122
Multifunctional delivery strategies and nanoplatforms of SN-38 in cancer therapeutics	121
Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors	119
The inflammatory bowel disease and gut microbiome are restored by employing metformin-loaded alginate-shelled microcapsules	118
Micellar paclitaxel boosts ICD and chemo-immunotherapy of metastatic triple negative breast cancer	117
White paper: Understanding, informing and defining the regulatory science of microneedle-based dosage forms that are applied to the skin	116
Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications	116
Site-specific engineering of S-Te-S bridged nano-prodrug: A dual equilibrium strategy for enhanced antitumor efficacy and safety of paclitaxel	115
Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice	114
Conditioned media-integrated microneedles for hair regeneration through perifollicular angiogenesis	114
Modified montmorillonite armed probiotics with enhanced on-site mucus-depleted intestinal colonization and H2S scavenging for colitis treatment	113
Microneedle-mediated nose-to-brain drug delivery for improved Alzheimer's disease treatment	113
Injectable nanocomposite hydrogel with cascade drug release for treatment of uveal melanoma	110
Self-assembly hydrogels of therapeutic agents for local drug delivery	108
Functional nanoplatform for modulating cellular forces to enhance antitumor immunity via mechanotransduction	107
Identification of functional biomarkers for personalized nanomedicine in advanced breast cancer in vitro models	106
Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis	106
Engineered exosomes with enhanced stability and delivery efficiency for glioblastoma therapy	105
A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes	105
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs	104
Transdermal carbon monoxide delivery	104
A next-generation STING agonist MSA-2: From mechanism to application	104
Hybrid prodrug nanoassembly for hypoxia-triggered immunogenic chemotherapy and immune modulation	103
Intraperitoneal drug delivery systems for peritoneal carcinomatosis: Bridging the gap between research and clinical implementation	103
Orthogonal upconversion nanocarriers for combined photodynamic therapy and precisely triggered gene silencing in combating keloids	103
Mechanisms of uptake and transport of particulate formulations in the small intestine	103
Accelerated blood clearance of PEGylated nanoparticles induced by PEG-based pharmaceutical excipients	102
In vivo delivery of antioxidant enzymes with multi-functionalized lipid nanoparticles for sepsis therapy	101
Dual-stimulus phototherapeutic nanogel for triggering pyroptosis to promote cancer immunotherapy	101

Nanoparticle-mediated thermal Cancer therapies: Strategies to improve clinical translatability	101
Biomimetic reactive oxygen/nitrogen nanoscavengers inhibit “ferroptosis storm” and modulate immune targeting for acute kidney injury	99
In-situ-formed immunotherapeutic and hemostatic dual drug-loaded nanohydrogel for preventing postoperative recurrence of hepatocellular carcinoma	98
Healing with precision: A multi-functional hydrogel-bioactive glass dressing boosts infected wound recovery and enhances neurogenesis in the wound bed	97
Mechanism exploration of intestinal mucus penetration of nano-Se: regulated by polysaccharides with different functional groups and molecular weights	97
Metal-phenolic network-based polymeric nanocarriers facilitating antibody cytoplasmic delivery and anti-tumor effects to orthotopic breast tumors	97
Macrophage-targeting nano-formulated bicalutamide alleviates colitis by inducing MAP3K1-mediated degradation of NLRP3	97
Hydrogel-forming microarray patches with solid dispersion reservoirs for transdermal long-acting microdepot delivery of a hydrophobic drug	96
The osteogenic and angiogenic potential of microRNA-26a delivered via a non-viral delivery peptide for bone repair	96
Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity	95
Delivery of DNA octahedra enhanced by focused ultrasound with microbubbles for glioma therapy	95
Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis	94
Targosomes: Anti-HER2 PLGA nanocarriers for bioimaging, chemotherapy and local photothermal treatment of tumors and remote metastases	94
Alendronate-functionalized polymeric micelles target icaritin to bone for mitigating osteoporosis in a rat model	94
Pickering emulsion-guided monomeric delivery of monophosphoryl lipid A for enhanced vaccination	92
A smart cauliflower-like carrier for astaxanthin delivery to relieve colon inflammation	91
Full-cycle study on developing a novel structured micromixer and evaluating the nanoparticle products as mRNA delivery carriers	91