Journal of Biotechnology

Papers
(The TQCC of Journal of Biotechnology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
OptMSP: A toolbox for designing optimal multi-stage (bio)processes233
In vitro response of sugarcane (Saccharum spp. Hybrid) plantlets to flooding stress116
Epitope mapping of nanobodies binding the Alzheimer’s disease receptor SORLA105
Low specific growth rate and temperature in fed-batch cultures of a beta-propeller phytase producing Pichia pastoris strain under GAP promoter trigger increased KAR2 and PSA1-1 gene expression yieldin81
In silico design of CMV promoter binding oligonucleotides and their impact on inhibition of gene expression in Chinese hamster ovary cells80
Development of transgenic algae strain expressing CTB-M2e fusion gene an approach towards the development of a universal edible vaccine in algae78
Editorial Board78
Optimisation of coumaric acid production from aromatic amino acids in Kluyveromyces marxianus67
Enhancement of the production of terpenoid and flavonoid secondary metabolites in the ground and aerial parts of licorice composite plant in a hydroponic system61
Engineering the activity and thermostability of a carboxylic acid reductase in the conversion of vanillic acid to vanillin60
Engineering of a bacterial outer membrane vesicle to a nano-scale reactor for the biodegradation of β-lactam antibiotics54
Biotechnology under extreme conditions: Lichens after extreme UVB radiation and extreme temperatures produce large amounts of hydrogen54
The physiological role of gamma-aminobutyric acid in relieving the effect of furfural inhibitor for improvement the production of lipid in D. intermedius Z852
In vitro synthesis of oryzamutaic acid H using recombinant L-lysine ε-dehydrogenase from Agrobacterium tumefaciens48
Target-directed evolution of novel modulators of the dopamine transporter in Lobelia cardinalis hairy root cultures48
A novel magnet-driven rotary mixing aerator for carbon dioxide fixation and microalgae cultivation: Focusing on bubble behavior and cultivation performance43
Engineering of a fungal steroid 11α-hydroxylase and construction of recombinant yeast for improved production of 11α-hydroxyprogesterone42
Rational engineering of phospholipase C from Bacillus cereus HSL3 for simultaneous thermostability and activity improvement40
Production of fucoxanthin from the microalga Tisochrysis lutea in the bubble column photobioreactor applying mass transfer coefficient39
Using gel microdroplets to develop a simple high-throughput screening platform for oleaginous microorganisms39
Automated multi-scale cascade of parallel stirred-tank bioreactors for fast protein expression studies38
Application of a biosurfactant from Pseudomonas cepacia CCT 6659 in bioremediation and metallic corrosion inhibition processes37
Culture medium optimization for producing biomethane by coal anaerobic digestion36
Production of (−)-α-bisabolol in metabolically engineered Saccharomyces cerevisiae36
Isolation of indole-3-acetic acid-producing Azospirillum brasilense from Vietnamese wet rice: Co-immobilization of isolate and microalgae as a sustainable biorefinery35
Strategies and advances in the pretreatment of microalgal biomass35
Enhanced methanol-xylose co-utilization strategy in Komagataella phaffii33
Investigating subpopulation dynamics in clonal CHO-K1 cells with single-cell RNA sequencing33
Facile biosynthesis of synthetic crystalline cellulose nanoribbon from maltodextrin through a minimized two-enzyme phosphorylase cascade and its application in emulsion32
Cultivation of two Chlorella species in Open sewage contaminated channel wastewater for biomass and biochemical profiles: Comparative lab-scale approach32
Employment of light-inducible promoter in genetically engineered cyanobacteria for photosynthetic isobutanol production with simulated diurnal sunlight and CO232
Magnetic carboxymethyl cellulose-silk fibroin hydrogel: A ternary nanobiocomposite exhibiting excellent biological activity and in vitro hyperthermia of cancer therapy32
Mathematical model of the multi-amino acid multi-transporter system predicts uptake flux in CHO cells32
Synthesis and characterization of phase shift dextran stabilized nanodroplets for ultrasound-induced cancer therapy: A novel nanobiotechnology approach31
A modified method of gene disruption in Komagataella phaffii with Cre/loxP system29
UV and chemically induced Halomonas smyrnensis mutants for enhanced levan productivity29
Improved production of D-pantothenic acid in Escherichia coli by integrated strain engineering and fermentation strategies28
High-yield soluble production of recombinant β-keratin from Gallus gallus feathers using an experimental design approach26
Editorial Board26
Towards commercial levels of astaxanthin production in Phaffia rhodozyma25
Perspective of ACC-deaminase producing bacteria in stress agriculture25
Conjugation of haloalkane dehalogenase DhaA with arabinogalactan to increase its stability25
Plant-based synthesis, characterization approaches, applications and toxicity of silver nanoparticles: A comprehensive review24
Regulation of hydraulic retention time on caproic acid production via two-phase anaerobic fermentation of Chinese cabbage waste with autopoietic electron donors24
Strong negative correlation between codon usage bias and protein structural disorder impedes protein expression after codon optimization24
In-line monitoring of bioreactor by Raman spectroscopy: Direct use of a standard-based model through cell-scattering correction24
The synergistic actions of hydrolytic genes reveal the mechanism of Trichoderma harzianum for cellulose degradation23
Saline extraction assisted by ultrasound: a method to obtain purified phycocyanin23
Development of Stephania tetrandra S. MOORE hairy root culture process for tetrandrine production23
Editorial Board23
Probing the interaction of zinc oxide nanorods with human serum albumin: A spectroscopic approach22
Nano-managing silver and zinc as bio-conservational approach against pathogens of the honey bee22
Extending galactose-oxidation pathway of Pseudomonas putida for utilization of galactose-rich red macroalgae as sustainable feedstock21
A transposon system for random insertion of a gene expression cassette into the chromosome of Bacillus subtilis21
Advancements in enzymatic biotransformation and bioactivities of rare ginsenosides: A review21
Elucidation of the fucose metabolism of probiotic Lactobacillus rhamnosus GG by metabolomic and flux balance analyses20
Enhanced conversion of biomass to furfurylamine with high productivity by tandem catalysis with sulfonated perlite and ω-transaminase whole-cell biocatalyst20
Reviewing critical TRPM2 variants through a structure-function lens20
High-level expression and characterization of a highly active hyaluronate lyase HylC with significant potential in hyaluronan oligosaccharide preparation20
Impact of glgA1, glgA2 or glgC overexpression on growth and glycogen production in Synechocystis sp. PCC 680320
2′-Fucosyllactose production in engineered Escherichia coli with deletion of waaF and wcaJ and overexpression of FucT219
Ni2+-induced selective precipitation of His-tagged recombinant proteins shortens purification time while maintaining high yield19
Analysis of population heterogeneity in CHO cells by genome-wide DNA methylation analysis and by multi-modal single-cell sequencing19
Development of a highly efficient microbial fermentation process of recombinant Escherichia coli for GABA production from glucose19
Using synthetic biology to improve photosynthesis for sustainable food production18
Enhanced laccase separation from fermentation medium using cryogel columns18
Thermal degradation kinetics and purification of C-phycocyanin from thermophilic and mesophilic cyanobacteria18
Editorial Board18
The down-regulation of melanogenesis via MITF and FOXO1 signaling pathways in SIRT1 knockout cells using CRISPR/Cas9 system17
Metabolic rewiring revealed by cell-specific rate analyses from nontargeted exometabolomics during simultaneous consumption of glucose and lactic acid in a CHO fed-batch process17
Production of recombinant human type I collagen homotrimers in CHO cells and their physicochemical and functional properties17
pH-dependent electrostatic interactions between enzymes and nanoparticles in Pickering emulsions – Influence on activity and droplet size17
A combination strategy of solubility enhancers for effective production of soluble and bioactive human enterokinase17
Multiple genome analytics framework: The case of all SARS-CoV-2 complete variants17
Production of C20, C30 and C40 terpenes in the engineered phototrophic bacterium Rhodobacter capsulatus17
Enrichment of Methylocystis dominant mixed culture from rice field for PHB production16
Metabolic engineering of Schizosaccharomyces pombe for itaconic acid production16
Low-cost alternative for the bioproduction of bioactive phenolic compounds of callus cultures from Cereus hildmannianus (K.) Schum16
Metabolic and biotechnological insights on the analysis of the Pdh bypass and acetate production in the yeast Dekkera bruxellensis16
Development of thermostable dextranase from Streptococcus mutans (SmdexTM) through in silico design employing B-factor and Cartesian-ΔΔG16
Weak promoters to drive selection marker expression: Improvement of cell line development process for therapeutic protein production in CHO-K1 cells16
Strategic feeding of NS0 and CHO cell cultures to control glycan profiles and immunogenic epitopes of monoclonal antibodies16
Microbial production of mevalonate16
Alleviation of cadmium toxicity and minimizing its accumulation in rice plants by methyl jasmonate: Performance and mechanisms15
Biosurfactants as microbial bioactive compounds in microbial enhanced oil recovery15
Editorial Board15
Extension of the circulatory half-life of recombinant ecallantide via albumin fusion without loss of anti-kallikrein activity15
A comprehensive overview of nanotechnology in sustainable agriculture15
Syntrophy of Crypthecodinium cohnii and immobilized Zymomonas mobilis for docosahexaenoic acid production from sucrose-containing substrates15
Hemp tea waste-immobilized lipase for the synthesis of alkyl oleates in solvent free systems15
Characterization of free and immobilized lipase from Penicillium sp. onto three modified bentonites: A comparative study15
UV-ARTP compound mutagenesis breeding improves macrolactins production of Bacillus siamensis and reveals metabolism changes by proteomic15
Ozonation process causes changes in PARP-1 expression and the metabolism of NADPH in strawberry fruit during storage15
QTL mapping in sesame (Sesamum indicum L.): A review15
Expediting adenovirus titer assays via an algorithmic live-cell imaging technique15
Genetic transformation of ‘Hamlin’ and ‘Valencia’ sweet orange plants expressing the cry11A gene of Bacillus thuringiensis as an additional tool for the management of Diaphorina citri (Hemiptera: Livi15
A novel directed evolution approach for co-evolution of β-glucosidase activity and organic acid tolerance15
Enhanced activation of signaling pathway by recombinant human adiponectin from genome-edited chickens15
Novel intein-based self-cleaving affinity tag for recombinant protein production in Escherichia coli14
Halophilic filamentous fungi and their enzymes: Potential biotechnological applications14
Cd2+ tolerance and removal mechanisms of Serratia marcescens KMR-314
Very high gravity ethanol fermentation from sweet sorghum stem juice using a stirred tank bioreactor coupled with a column bioreactor14
Novel efficient enzymatic synthesis of the key-reaction intermediate of PET depolymerization, mono(2-hydroxyethyl terephthalate) – MHET14
Development of a new extraction method and functional analysis of phycocyanobilin from unique filamentous cyanobacteria13
Enhancement of catabolite regulatory genes in Saccharomyces cerevisiae to increase ethanol production using hydrolysate from red seaweed Gloiopeltis furcata13
Inhibition of the JAZ1 gene causes activation of camalexin biosynthesis in Arabidopsis callus cultures13
Diel biochemical and photosynthetic monitorization of Skeletonema costatum and Phaeodactylum tricornutum grown in outdoor pilot-scale flat panel photobioreactors13
Effect of selenium and tungsten on cell growth and metabolite production in syngas fermentation using “Clostridium autoethanogenum”13
Thermodynamics of microbial consortia: Enthalpies and Gibbs energies of microorganism live matter and macromolecules of E. coli, G. oxydans, P. fluorescens, S. thermophilus and P. chrysogenum13
Editorial Board13
Pretreatment of lignocellulosic biogas substrates by filamentous fungi13
Light intensity and spectral quality modulation for improved growth kinetics and biochemical composition of Chlamydomonas reinhardtii13
Editorial Board13
Integrating genetic assortment and molecular insights for climate-resilient breeding to unravel drought tolerance in cotton13
Genomic features of recombinant CHO clones arising from transposon-based and randomized integration13
Engineered praseodymium sulfide nanocarrier and supramolecular association of anticancer drug for effective delivery to breast cancer cells13
Editorial Board12
Editorial Board12
Enhanced molecular stability of ApxII antigen during secretion in Corynebacterium glutamicum by rational design12
Investigation into optimizing fermentation processes to enhance uric acid degradation by probiotics12
Expression of a recombinant protein by an acetic acid bacterial host12
Editorial Board12
Engineering Saccharomyces boulardii for cell surface display of heterologous protein12
Assessing site-specific PEGylation of TEM-1 β-lactamase with cell-free protein synthesis and coarse-grained simulation12
Corrigendum to “A cheap two-step cultivation of Phaeodactylum tricornutum for increased TAG production and differential expression of TAG biosynthesis associated genes” [J. Biotechnol. 354 (2022) 53–612
Optimization of fungal fermentation for the extraction of polyphenols from Flourensia cernua and its effect on cellular metabolism12
Optimizing mycelial protein yield in Pleurotus djamor via ARTP mutagenesis and hybridization strategies12
Priming with EDTA, IAA and Fe alleviates Pb toxicity in Trigonella Foneum graecum L. growth: Phytochemicals and secondary metabolites12
Digital holographic microscopy is suitable for lipid accumulation analysis in single cells of Yarrowia lipolytica12
Harnessing nature's catalysts: Advances in enzymatic alkene cleavage12
Improved biocatalytic activity of steapsin lipase in supercritical carbon dioxide medium for the synthesis of benzyl butyrate: A commercially important flavour compound11
Production of antimicrobial peptide arasin-like Sp in Escherichia coli via an ELP-intein self-cleavage system11
Lipase-mediated alcoholysis for in situ production of ester bioaromas in licuri oil for cosmetic applications11
Development of a 10 g/L process for a difficult-to-express multispecific antibody format using a holistic process development approach11
Experimental and mathematical modeling approaches for biocatalytic post-consumer poly(ethylene terephthalate) hydrolysis11
P3HT-based organic field effect transistor for low-cost, label-free detection of immunoglobulin G11
Valorisation of waste cooking oil using mixed culture into short- and medium-chain length polyhydroxyalkanoates: Effect of concentration, temperature and ammonium11
Volatile organic compounds: A threat to the environment and health hazards to living organisms – A review11
Low-molecular-weight impurity in Poloxamer 188 responsible for atypical cell culture performance for mAb production11
Editorial Board11
Continuous purification of influenza A virus particles using pseudo-affinity membrane chromatography11
Oxidative torrefaction performance of microalga Nannochloropsis Oceanica towards an upgraded microalgal solid biofuel11
A review on anticancer, antibacterial and photo catalytic activity of various nanoparticles synthesized by probiotics11
Progress on production of malic acid and succinic acid by industrially-important engineered microorganisms11
Investigation of anti-adherence and antimicrobial properties of prodigiosin-functionalized bacterial cellulose membrane for biomedical applications11
Optimizing bio-vanillin synthesis from ferulic acid via Pediococcus acidilactici: A systematic approach to process enhancement and yield maximization10
Editorial Board10
A highly efficient mixed strain fermentation strategy to produce 11α-Hydroxyandrost-4-ene-3,17-dione from phytosterols10
Immobilization of aldoxime dehydratases on metal affinity resins and use of the immobilized catalysts for the synthesis of nitriles important in fragrance industry10
Cell-based shear stress sensor for bioprocessing10
Advancement on mixed microalgal-bacterial cultivation systems for nitrogen and phosphorus recoveries from wastewater to promote sustainable bioeconomy10
Phycobilin heterologous production from the Rhodophyta Porphyridium cruentum10
Reduced production of Ethyl Carbamate in wine by regulating the accumulation of arginine in Saccharomyces cerevisiae10
Editorial Board10
Molecular biomarkers identification and applications in CHO bioprocessing10
Selection of initial culture medium in fed-batch bioreactor culture of Rhodiola sachalinensis cells10
Evaluating the role of trypsin in silk degumming: An in silico approach10
Enhancing the amination activity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum by modifying the crucial residue His154 for deamination10
Editorial Board10
Virion-surface display of a chimeric immunoglobulin Fc domain facilitating uptake by antigen-presenting cells10
A pump-free microfluidic co-culture system for investigating NK cell-tumor spheroid interactions in flow conditions10
Affinity precipitation of monoclonal antibodies using ELP-Z in the elution without resolubilization mode10
Bioeffects of static magnetic fields on the growth and metabolites of C. pyrenoidosa and T. obliquus10
Customized design of host-independent T7 expression system (HITES) for a broad host range10
Comparison of plant biostimulating properties of Chlorella sorokiniana biomass produced in batch and semi-continuous systems supplemented with pig manure or acetate10
RNA-based detection of genetically modified plants via current-voltage characteristic measurement9
Enhanced prokaryotic expression, purification, and biological activities of human keratinocyte growth factor9
Structure-guided engineering of 4-coumarate: CoA ligase for efficient production of rosmarinic acid in Saccharomyces cerevisiae9
High yield secretion of human erythropoietin from tobacco cells for ex vivo differentiation of hematopoietic stem cells towards red blood cells9
Microalgae as a potential therapeutic drug candidate for neurodegenerative diseases9
Interferon inhibitors increase rAAV production in HEK293 cells9
Impact of liquid and solid-state cultures on hemoglobin production and oxidative state in Saccharomyces cerevisiae9
Editorial Board9
Glycolate as alternative carbon source for Escherichia coli9
N-region of Cry1Ia: A novel fusion tag for Escherichia coli and Pichia pastoris9
Advances in photonic crystal hydrogels for biomedical research: A review9
Production of hesperetin from naringenin in an engineered Escherichia coli consortium9
Unlocking new frontiers in healthcare: The impact of nano-optical biosensors on personalized medical diagnostics9
Sortase E-mediated site-specific immobilization of green fluorescent protein and xylose dehydrogenase on gold nanoparticles9
System-wide analysis of groundnut's salinity resilience: Integrating plant-cell interactions with environmental stress dynamics through cutting-edge transcriptomics9
Endophyte-assisted non-host plant Tillandsia brachycaulos enhance indoor formaldehyde removal9
Streamlined in vitro screening system of synthetic signal peptides in Chinese hamster ovary cells for therapeutic protein production9
Indole-3-butyric acid mediated growth and biochemical enhancement in three Selenastracean green microalgae under limited supply of nitrogen source9
Fuel characterization, engine performance characteristics and emissions analysis of different mustard seed biodiesel: An overview9
Preparation and identification of carboxymethyl cellulose-degrading enzyme candidates for oilfield applications9
Ectoine production from a novel bacterial strain and high-purity purification with a cost-effective and single-step method9
Engineering the cell wall reactive groups of Plant Growth Promoting Rhizobacteria by culture strategy for heavy metal removal9
Bone marrow-derived dendritic cells play a role in attenuating inflammation on Bothrops jararacussu venom muscle damage9
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