Journal of Biotechnology

Article	Citations
Branched-chain polyamine beads for sensitive recovery and detection of low-copy DNA in aqueous solutions	145
The physiological role of gamma-aminobutyric acid in relieving the effect of furfural inhibitor for improvement the production of lipid in D. intermedius Z8	107
Optimisation of coumaric acid production from aromatic amino acids in Kluyveromyces marxianus	105
Target-directed evolution of novel modulators of the dopamine transporter in Lobelia cardinalis hairy root cultures	96
OptMSP: A toolbox for designing optimal multi-stage (bio)processes	85
In silico design of CMV promoter binding oligonucleotides and their impact on inhibition of gene expression in Chinese hamster ovary cells	76
In vitro synthesis of oryzamutaic acid H using recombinant L-lysine ε-dehydrogenase from Agrobacterium tumefaciens	67
Engineering of a fungal steroid 11α-hydroxylase and construction of recombinant yeast for improved production of 11α-hydroxyprogesterone	64
Editorial Board	59
Using gel microdroplets to develop a simple high-throughput screening platform for oleaginous microorganisms	53
Low specific growth rate and temperature in fed-batch cultures of a beta-propeller phytase producing Pichia pastoris strain under GAP promoter trigger increased KAR2 and PSA1-1 gene expression yieldin	49
Rational engineering of phospholipase C from Bacillus cereus HSL3 for simultaneous thermostability and activity improvement	45
Isolation of indole-3-acetic acid-producing Azospirillum brasilense from Vietnamese wet rice: Co-immobilization of isolate and microalgae as a sustainable biorefinery	44
Development of transgenic algae strain expressing CTB-M2e fusion gene an approach towards the development of a universal edible vaccine in algae	44
Enhanced tolerance of Clostridium tyrobutyricum to lignin-derived phenolic acids by overexpressing native reductases	43
Engineering the activity and thermostability of a carboxylic acid reductase in the conversion of vanillic acid to vanillin	43
Epitope mapping of nanobodies binding the Alzheimer’s disease receptor SORLA	42
Fungal elicitors increase cell biomass, pyrroloquinazoline alkaloids production and gene expression levels of biosynthetic pathways in Adhatoda vasica Nees cell cultures	40
Short-term effect of biologically treated sugarcane vinasse on the growth of Triticum aestivum L. (wheat) and soil properties	39
Investigating subpopulation dynamics in clonal CHO-K1 cells with single-cell RNA sequencing	38
Retraction notice to “A recombinant H1 histone based system for efficient delivery of nucleic acids” [J. Biotechnol. 105 (2003) 215–226]	38
Enhancement of the production of terpenoid and flavonoid secondary metabolites in the ground and aerial parts of licorice composite plant in a hydroponic system	37
Engineering of a bacterial outer membrane vesicle to a nano-scale reactor for the biodegradation of β-lactam antibiotics	36
In vitro response of sugarcane (Saccharum spp. Hybrid) plantlets to flooding stress	35
Biotechnology under extreme conditions: Lichens after extreme UVB radiation and extreme temperatures produce large amounts of hydrogen	34

A novel dynamic flux balance analysis for modeling CHO cell fed-batch cultures with pH and temperature shifts	33
A novel magnet-driven rotary mixing aerator for carbon dioxide fixation and microalgae cultivation: Focusing on bubble behavior and cultivation performance	32
Production of fucoxanthin from the microalga Tisochrysis lutea in the bubble column photobioreactor applying mass transfer coefficient	32
Application of a biosurfactant from Pseudomonas cepacia CCT 6659 in bioremediation and metallic corrosion inhibition processes	32
Culture medium optimization for producing biomethane by coal anaerobic digestion	31
Enhanced methanol-xylose co-utilization strategy in Komagataella phaffii	30
High-yield soluble production of recombinant β-keratin from Gallus gallus feathers using an experimental design approach	28
Towards commercial levels of astaxanthin production in Phaffia rhodozyma	28
Editorial Board	28
Synthesis and characterization of phase shift dextran stabilized nanodroplets for ultrasound-induced cancer therapy: A novel nanobiotechnology approach	27
Microwave-assisted biogenic synthesis of pure copper oxide nanoparticles by Lepidium sativum L. leaves extract: Characterization and evaluation of antibacterial activity	27
Magnetic carboxymethyl cellulose-silk fibroin hydrogel: A ternary nanobiocomposite exhibiting excellent biological activity and in vitro hyperthermia of cancer therapy	27
A modified method of gene disruption in Komagataella phaffii with Cre/loxP system	25
Perspective of ACC-deaminase producing bacteria in stress agriculture	25
Employment of light-inducible promoter in genetically engineered cyanobacteria for photosynthetic isobutanol production with simulated diurnal sunlight and CO2	25
Novel approaches to engineering autolysis: A scalable alternative for recovery of bioproducts.	25
Strong negative correlation between codon usage bias and protein structural disorder impedes protein expression after codon optimization	24
Cultivation of two Chlorella species in Open sewage contaminated channel wastewater for biomass and biochemical profiles: Comparative lab-scale approach	24
Mathematical model of the multi-amino acid multi-transporter system predicts uptake flux in CHO cells	24
Regulation of hydraulic retention time on caproic acid production via two-phase anaerobic fermentation of Chinese cabbage waste with autopoietic electron donors	24
Bioprocessing of pineapple leaf waste biomass using an integrated ultrasound-deep eutectic solvent pretreatment approach for improved bioethanol production	23
UV and chemically induced Halomonas smyrnensis mutants for enhanced levan productivity	23
Advancements in transient overexpression systems for enhanced recombinant protein production in lettuce	22
Editorial Board	22
Reviewing critical TRPM2 variants through a structure-function lens	22
Plant-based synthesis, characterization approaches, applications and toxicity of silver nanoparticles: A comprehensive review	22
Enhancing the extraction of C-phycocyanin and water-soluble metabolites from Arthrospira platensis using pulsed electric field technology	21
Efficient biosynthesis of ectoine in engineered Vibrio natriegens	21
Elucidation of the fucose metabolism of probiotic Lactobacillus rhamnosus GG by metabolomic and flux balance analyses	21
A transposon system for random insertion of a gene expression cassette into the chromosome of Bacillus subtilis	21
Extending galactose-oxidation pathway of Pseudomonas putida for utilization of galactose-rich red macroalgae as sustainable feedstock	21
Probing the interaction of zinc oxide nanorods with human serum albumin: A spectroscopic approach	21
Channel matters: Overcoming diffusion bottlenecks via loop engineering of LinD for enhanced isoprene production	20
Ni2+-induced selective precipitation of His-tagged recombinant proteins shortens purification time while maintaining high yield	20
In-line monitoring of bioreactor by Raman spectroscopy: Direct use of a standard-based model through cell-scattering correction	20
High-level expression and characterization of a highly active hyaluronate lyase HylC with significant potential in hyaluronan oligosaccharide preparation	19
Development of Stephania tetrandra S. MOORE hairy root culture process for tetrandrine production	19
Fragmentation of recombinant human interleukin-12 by matriptase in CHO cell culture	19
Development of a highly efficient microbial fermentation process of recombinant Escherichia coli for GABA production from glucose	19
Establishment of high-efficiency hairy root and genetic transformation system in Cynanchum stauntonii	19
Analysis of population heterogeneity in CHO cells by genome-wide DNA methylation analysis and by multi-modal single-cell sequencing	18
Metabolic rewiring revealed by cell-specific rate analyses from nontargeted exometabolomics during simultaneous consumption of glucose and lactic acid in a CHO fed-batch process	18
Saline extraction assisted by ultrasound: a method to obtain purified phycocyanin	18
Advancements in enzymatic biotransformation and bioactivities of rare ginsenosides: A review	18
Editorial Board	18
Nano-managing silver and zinc as bio-conservational approach against pathogens of the honey bee	18
High-throughput flow cytometry-based titration of a live attenuated rotavirus vaccine	18
Biosurfactants as microbial bioactive compounds in microbial enhanced oil recovery	17
Metabolic and biotechnological insights on the analysis of the Pdh bypass and acetate production in the yeast Dekkera bruxellensis	17
Alleviation of cadmium toxicity and minimizing its accumulation in rice plants by methyl jasmonate: Performance and mechanisms	17

The down-regulation of melanogenesis via MITF and FOXO1 signaling pathways in SIRT1 knockout cells using CRISPR/Cas9 system	17
Weak promoters to drive selection marker expression: Improvement of cell line development process for therapeutic protein production in CHO-K1 cells	17
Low-cost alternative for the bioproduction of bioactive phenolic compounds of callus cultures from Cereus hildmannianus (K.) Schum	17
Development of thermostable dextranase from Streptococcus mutans (SmdexTM) through in silico design employing B-factor and Cartesian-ΔΔG	16
Microbial production of mevalonate	16
Enhanced laccase separation from fermentation medium using cryogel columns	16
pH-dependent electrostatic interactions between enzymes and nanoparticles in Pickering emulsions – Influence on activity and droplet size	16
Metabolic engineering of Schizosaccharomyces pombe for itaconic acid production	16
Thermal degradation kinetics and purification of C-phycocyanin from thermophilic and mesophilic cyanobacteria	16
Improving thermostability of α-L-fucosidase from Pedobacter sp. via consensus-guided engineering and directed evolution	16
Editorial Board	15
Using synthetic biology to improve photosynthesis for sustainable food production	15
Enrichment of Methylocystis dominant mixed culture from rice field for PHB production	15
Enhanced activation of signaling pathway by recombinant human adiponectin from genome-edited chickens	15
Genetic transformation of ‘Hamlin’ and ‘Valencia’ sweet orange plants expressing the cry11A gene of Bacillus thuringiensis as an additional tool for the management of Diaphorina citri (Hemiptera: Livi	15
Multiple genome analytics framework: The case of all SARS-CoV-2 complete variants	15
Expediting adenovirus titer assays via an algorithmic live-cell imaging technique	15
QTL mapping in sesame (Sesamum indicum L.): A review	15
Halophilic filamentous fungi and their enzymes: Potential biotechnological applications	15
Production of recombinant human type I collagen homotrimers in CHO cells and their physicochemical and functional properties	15
A comprehensive overview of nanotechnology in sustainable agriculture	15
Development of a new extraction method and functional analysis of phycocyanobilin from unique filamentous cyanobacteria	15
A novel directed evolution approach for co-evolution of β-glucosidase activity and organic acid tolerance	15
Ozonation process causes changes in PARP-1 expression and the metabolism of NADPH in strawberry fruit during storage	14
Cd2+ tolerance and removal mechanisms of Serratia marcescens KMR-3	14
Characterization of free and immobilized lipase from Penicillium sp. onto three modified bentonites: A comparative study	14
Enhancing secondary metabolite biosynthesis from ethnomedicinal plant Solanum nigrum L. through cytogenetically stable mass propagation, transgenic hairy root induction, and using different LED light	14
Novel efficient enzymatic synthesis of the key-reaction intermediate of PET depolymerization, mono(2-hydroxyethyl terephthalate) – MHET	14
Microbial production of single cell oil from biowaste-derived volatile fatty acids using a newly identified oleaginous Cyberlindnera jadinii	14
Ethanolysis of degummed soybean oil using magnetic CLEAs from Eversa® Transform	14
Extension of the circulatory half-life of recombinant ecallantide via albumin fusion without loss of anti-kallikrein activity	14
Light intensity and spectral quality modulation for improved growth kinetics and biochemical composition of Chlamydomonas reinhardtii	14
Editorial Board	13
Genomic features of recombinant CHO clones arising from transposon-based and randomized integration	13
Pretreatment of lignocellulosic biogas substrates by filamentous fungi	13
UV-ARTP compound mutagenesis breeding improves macrolactins production of Bacillus siamensis and reveals metabolism changes by proteomic	13
Integrating genetic assortment and molecular insights for climate-resilient breeding to unravel drought tolerance in cotton	13
Engineered praseodymium sulfide nanocarrier and supramolecular association of anticancer drug for effective delivery to breast cancer cells	13
Inhibition of the JAZ1 gene causes activation of camalexin biosynthesis in Arabidopsis callus cultures	13
Hemp tea waste-immobilized lipase for the synthesis of alkyl oleates in solvent free systems	13
Thermodynamics of microbial consortia: Enthalpies and Gibbs energies of microorganism live matter and macromolecules of E. coli, G. oxydans, P. fluorescens, S. thermophilus and P. chrysogenum	13
Diel biochemical and photosynthetic monitorization of Skeletonema costatum and Phaeodactylum tricornutum grown in outdoor pilot-scale flat panel photobioreactors	13
Progress on production of malic acid and succinic acid by industrially-important engineered microorganisms	12
Editorial Board	12
Editorial Board	12
Improved biocatalytic activity of steapsin lipase in supercritical carbon dioxide medium for the synthesis of benzyl butyrate: A commercially important flavour compound	12
Editorial Board	12
A review on anticancer, antibacterial and photo catalytic activity of various nanoparticles synthesized by probiotics	12
P3HT-based organic field effect transistor for low-cost, label-free detection of immunoglobulin G	12
Application of a novel virus-like particle platform to the development of Neisseria vaccines	12
Harnessing nature's catalysts: Advances in enzymatic alkene cleavage	12
Effect of selenium and tungsten on cell growth and metabolite production in syngas fermentation using “Clostridium autoethanogenum”	12
Corrigendum to “A cheap two-step cultivation of Phaeodactylum tricornutum for increased TAG production and differential expression of TAG biosynthesis associated genes” [J. Biotechnol. 354 (2022) 53–6	12
Digital holographic microscopy is suitable for lipid accumulation analysis in single cells of Yarrowia lipolytica	12
Assessing site-specific PEGylation of TEM-1 β-lactamase with cell-free protein synthesis and coarse-grained simulation	12
Production and purification of recombinant long protein isoforms of FGF11 subfamily	12
Characterization of 3D-printed acrylonitrile butadiene styrene and polylactic acid carrier-beads for Gluconobacter oxydans immobilization	12
The CRISPR Cas patent files, part 4: All back to zero, think again!	12
Expression of a recombinant protein by an acetic acid bacterial host	12
Production of antimicrobial peptide arasin-like Sp in Escherichia coli via an ELP-intein self-cleavage system	12
Priming with EDTA, IAA and Fe alleviates Pb toxicity in Trigonella Foneum graecum L. growth: Phytochemicals and secondary metabolites	11
Lipase-mediated alcoholysis for in situ production of ester bioaromas in licuri oil for cosmetic applications	11
Optimizing mycelial protein yield in Pleurotus djamor via ARTP mutagenesis and hybridization strategies	11
Volatile organic compounds: A threat to the environment and health hazards to living organisms – A review	11
Selection of initial culture medium in fed-batch bioreactor culture of Rhodiola sachalinensis cells	11
Optimization of fungal fermentation for the extraction of polyphenols from Flourensia cernua and its effect on cellular metabolism	11
Enhanced molecular stability of ApxII antigen during secretion in Corynebacterium glutamicum by rational design	11
Low-molecular-weight impurity in Poloxamer 188 responsible for atypical cell culture performance for mAb production	11
High specificity of MsmCAR toward 4-hydroxyvaleric acid enables efficient 1,4-pentanediol production from biomass-derived levulinic acid	11
Editorial Board	11
Continuous purification of influenza A virus particles using pseudo-affinity membrane chromatography	11
Engineering Saccharomyces boulardii for cell surface display of heterologous protein	11
Investigation into optimizing fermentation processes to enhance uric acid degradation by probiotics	11
Valorisation of waste cooking oil using mixed culture into short- and medium-chain length polyhydroxyalkanoates: Effect of concentration, temperature and ammonium	11
A highly efficient mixed strain fermentation strategy to produce 11α-Hydroxyandrost-4-ene-3,17-dione from phytosterols	11
Editorial Board	11
Molecular biomarkers identification and applications in CHO bioprocessing	10
Immobilization of aldoxime dehydratases on metal affinity resins and use of the immobilized catalysts for the synthesis of nitriles important in fragrance industry	10
Development of a 10 g/L process for a difficult-to-express multispecific antibody format using a holistic process development approach	10
Virion-surface display of a chimeric immunoglobulin Fc domain facilitating uptake by antigen-presenting cells	10

Investigation of anti-adherence and antimicrobial properties of prodigiosin-functionalized bacterial cellulose membrane for biomedical applications	10
Modular engineering of the doxorubicin biosynthetic gene cluster based on component functional clustering in Streptomyces	10
Evaluating the role of trypsin in silk degumming: An in silico approach	10
Customized design of host-independent T7 expression system (HITES) for a broad host range	10
Synergistic interaction of AaMYC2 and AaMYC2-LIKE enhances artemisinin production in Artemisia annua L.	10
A pump-free microfluidic co-culture system for investigating NK cell-tumor spheroid interactions in flow conditions	10
Bioeffects of static magnetic fields on the growth and metabolites of C. pyrenoidosa and T. obliquus	10
Cell-based shear stress sensor for bioprocessing	10
Enhancing the amination activity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum by modifying the crucial residue His154 for deamination	10
Comparison of plant biostimulating properties of Chlorella sorokiniana biomass produced in batch and semi-continuous systems supplemented with pig manure or acetate	10
Editorial Board	10
Reduced production of Ethyl Carbamate in wine by regulating the accumulation of arginine in Saccharomyces cerevisiae	10
RNA-based detection of genetically modified plants via current-voltage characteristic measurement	9
Preparation and identification of carboxymethyl cellulose-degrading enzyme candidates for oilfield applications	9
Editorial Board	9
Microalgae as a potential therapeutic drug candidate for neurodegenerative diseases	9
Editorial Board	9
Bone marrow-derived dendritic cells play a role in attenuating inflammation on Bothrops jararacussu venom muscle damage	9
Interferon inhibitors increase rAAV production in HEK293 cells	9
Glycolate as alternative carbon source for Escherichia coli	9
System-wide analysis of groundnut's salinity resilience: Integrating plant-cell interactions with environmental stress dynamics through cutting-edge transcriptomics	9
Advancement on mixed microalgal-bacterial cultivation systems for nitrogen and phosphorus recoveries from wastewater to promote sustainable bioeconomy	9
Fuel characterization, engine performance characteristics and emissions analysis of different mustard seed biodiesel: An overview	9
Impact of liquid and solid-state cultures on hemoglobin production and oxidative state in Saccharomyces cerevisiae	9
Indole-3-butyric acid mediated growth and biochemical enhancement in three Selenastracean green microalgae under limited supply of nitrogen source	9
Production of hesperetin from naringenin in an engineered Escherichia coli consortium	9
Structure-guided engineering of 4-coumarate: CoA ligase for efficient production of rosmarinic acid in Saccharomyces cerevisiae	9
Engineering the cell wall reactive groups of Plant Growth Promoting Rhizobacteria by culture strategy for heavy metal removal	9
Sortase E-mediated site-specific immobilization of green fluorescent protein and xylose dehydrogenase on gold nanoparticles	9
Engineering adaptive alleles for Escherichia coli growth on sucrose using the EasyGuide CRISPR system	9
Engineered L-phenylserine aldolase enhances L-norvaline synthesis within an enzyme cascade	9
Ectoine production from a novel bacterial strain and high-purity purification with a cost-effective and single-step method	8
Identification and structure-based engineering of a dipeptidase CpPepD from Clostridium perfringens for the synthesis of l-carnosine	8
Immobilization of glycosyltransferase into a hydrophilic metal-organic framework for efficient biosynthesis of chondroitin sulfate	8
Constructing a methanol-dependent Bacillus subtilis by engineering the methanol metabolism	8
Streamlined in vitro screening system of synthetic signal peptides in Chinese hamster ovary cells for therapeutic protein production	8
Uncovering gene expression signatures and diagnostic – Biomarkers in hepatocellular carcinoma through multinomial logistic regression analysis	8
Editorial Board	8
High yield secretion of human erythropoietin from tobacco cells for ex vivo differentiation of hematopoietic stem cells towards red blood cells	8
Optimizing bio-vanillin synthesis from ferulic acid via Pediococcus acidilactici: A systematic approach to process enhancement and yield maximization	8
Enhanced prokaryotic expression, purification, and biological activities of human keratinocyte growth factor	8
pH-driven metabolic reprogramming in Bacillus velezensis 83 regulates metabolite synthesis and sporulation: A transcriptional approach for bioprocess development	8
Integrative in-silico models for mammalian cell cultures in single-use bioreactors: Bridging hydrodynamics, kinetics, and process control across scales	8
Re-examination of dilute acid hydrolysis of lignocellulose for production of cellulosic ethanol after de-bottlenecking the inhibitor barrier	8
Regulatory non-coding RNA: The core defense mechanism against plant pathogens	8
Microalgal drugs: A promising therapeutic reserve for the future	8
A chitosan-integrated antibacterial protein composite nanocomplex derived from barnacle cement and spider silk	8
Editorial Board	8
Advances in photonic crystal hydrogels for biomedical research: A review	8
Endophyte-assisted non-host plant Tillandsia brachycaulos enhance indoor formaldehyde removal	8
N-region of Cry1Ia: A novel fusion tag for Escherichia coli and Pichia pastoris	8
Metabolic engineering and high-cell-density fermentation of Corynebacterium glutamicum to improve isopropanol production	8
Enhancement of production of glycoalkaloids by elicitors along with characterization of gene expression of pathways in Solanum xanthocarpum	8
Multifactorial optimization enables the identification of a greener method to produce (+)-nootkatone	8
Identification and characterization of anaerobically activated promoters in Escherichia coli	8
Efficient multiplex CRISPR/Cpf1 (Cas12a) genome editing system in Aspergillus aculeatus TBRC 277	8
A statistical approach to boost soluble expression of E. coli-derived virus-like particles in shake-flask cultivation	8
Metabolic engineering of Escherichia coli for seleno-methylselenocysteine production	8
Unlocking new frontiers in healthcare: The impact of nano-optical biosensors on personalized medical diagnostics	8
A robust and efficient alluvial filtration method for the clarification of adeno-associated viruses from crude cell lysates	8