Journal of Biotechnology

Article	Citations
Rational engineering of phospholipase C from Bacillus cereus HSL3 for simultaneous thermostability and activity improvement	177
Branched-chain polyamine beads for sensitive recovery and detection of low-copy DNA in aqueous solutions	147
Enhanced tolerance of Clostridium tyrobutyricum to lignin-derived phenolic acids by overexpressing native reductases	122
Enhancement of the production of terpenoid and flavonoid secondary metabolites in the ground and aerial parts of licorice composite plant in a hydroponic system	110
In vitro response of sugarcane (Saccharum spp. Hybrid) plantlets to flooding stress	71
In silico design of CMV promoter binding oligonucleotides and their impact on inhibition of gene expression in Chinese hamster ovary cells	70
In vitro synthesis of oryzamutaic acid H using recombinant L-lysine ε-dehydrogenase from Agrobacterium tumefaciens	63
Engineering of a fungal steroid 11α-hydroxylase and construction of recombinant yeast for improved production of 11α-hydroxyprogesterone	55
Using gel microdroplets to develop a simple high-throughput screening platform for oleaginous microorganisms	54
Fungal elicitors increase cell biomass, pyrroloquinazoline alkaloids production and gene expression levels of biosynthetic pathways in Adhatoda vasica Nees cell cultures	52
Epitope mapping of nanobodies binding the Alzheimer’s disease receptor SORLA	50
Directional lactic acid production could mitigate antibiotic and ARGs pollution	48
Retraction notice to “A recombinant H1 histone based system for efficient delivery of nucleic acids” [J. Biotechnol. 105 (2003) 215–226]	48
Methanol-induced metabolic disturbances in protein expression in Pichia pastoris: A review of the interaction between amino acid synthesis and higher alcohol pathways	47
Engineering of a bacterial outer membrane vesicle to a nano-scale reactor for the biodegradation of β-lactam antibiotics	45
Optimisation of coumaric acid production from aromatic amino acids in Kluyveromyces marxianus	43
The physiological role of gamma-aminobutyric acid in relieving the effect of furfural inhibitor for improvement the production of lipid in D. intermedius Z8	42
Low specific growth rate and temperature in fed-batch cultures of a beta-propeller phytase producing Pichia pastoris strain under GAP promoter trigger increased KAR2 and PSA1-1 gene expression yieldin	42
OptMSP: A toolbox for designing optimal multi-stage (bio)processes	38
Application of a biosurfactant from Pseudomonas cepacia CCT 6659 in bioremediation and metallic corrosion inhibition processes	37
Marine-derived Streptomyces sp. isolated from the Persian Gulf as a novel source of melanin	35
Engineering the activity and thermostability of a carboxylic acid reductase in the conversion of vanillic acid to vanillin	35
Investigating subpopulation dynamics in clonal CHO-K1 cells with single-cell RNA sequencing	35
A novel dynamic flux balance analysis for modeling CHO cell fed-batch cultures with pH and temperature shifts	34
Ethanol alleviates glucose stress from Euglena gracilis	34

Development of a serum-free producer cell line generation process for scalable and efficient rAAV production for gene therapy applications	32
Short-term effect of biologically treated sugarcane vinasse on the growth of Triticum aestivum L. (wheat) and soil properties	32
Development of transgenic algae strain expressing CTB-M2e fusion gene an approach towards the development of a universal edible vaccine in algae	32
The complex patent situation regarding antibody Fc engineering	31
High-yield soluble production of recombinant β-keratin from Gallus gallus feathers using an experimental design approach	30
A novel magnet-driven rotary mixing aerator for carbon dioxide fixation and microalgae cultivation: Focusing on bubble behavior and cultivation performance	30
Editorial Board	29
Employment of light-inducible promoter in genetically engineered cyanobacteria for photosynthetic isobutanol production with simulated diurnal sunlight and CO2	27
Magnetic carboxymethyl cellulose-silk fibroin hydrogel: A ternary nanobiocomposite exhibiting excellent biological activity and in vitro hyperthermia of cancer therapy	26
Novel approaches to engineering autolysis: A scalable alternative for recovery of bioproducts.	25
Perspective of ACC-deaminase producing bacteria in stress agriculture	25
Microwave-assisted biogenic synthesis of pure copper oxide nanoparticles by Lepidium sativum L. leaves extract: Characterization and evaluation of antibacterial activity	25
UV and chemically induced Halomonas smyrnensis mutants for enhanced levan productivity	24
Enhancing heterotrophic lutein production in Chlorella protothecoides through combined phytohormone and nitrogen strategies	24
Plant-based synthesis, characterization approaches, applications and toxicity of silver nanoparticles: A comprehensive review	24
Bioprocessing of pineapple leaf waste biomass using an integrated ultrasound-deep eutectic solvent pretreatment approach for improved bioethanol production	23
Editorial Board	23
Regulation of hydraulic retention time on caproic acid production via two-phase anaerobic fermentation of Chinese cabbage waste with autopoietic electron donors	23
Enhanced methanol-xylose co-utilization strategy in Komagataella phaffii	23
Ni2+-induced selective precipitation of His-tagged recombinant proteins shortens purification time while maintaining high yield	22
Advancements in transient overexpression systems for enhanced recombinant protein production in lettuce	22
A transposon system for random insertion of a gene expression cassette into the chromosome of Bacillus subtilis	22
Nano-managing silver and zinc as bio-conservational approach against pathogens of the honey bee	21
Development of a highly efficient microbial fermentation process of recombinant Escherichia coli for GABA production from glucose	21
Fragmentation of recombinant human interleukin-12 by matriptase in CHO cell culture	21
Enhancing the extraction of C-phycocyanin and water-soluble metabolites from Arthrospira platensis using pulsed electric field technology	20
Efficient biosynthesis of ectoine in engineered Vibrio natriegens	20
In-line monitoring of bioreactor by Raman spectroscopy: Direct use of a standard-based model through cell-scattering correction	20
High-level expression and characterization of a highly active hyaluronate lyase HylC with significant potential in hyaluronan oligosaccharide preparation	20
Saline extraction assisted by ultrasound: a method to obtain purified phycocyanin	20
Development of Stephania tetrandra S. MOORE hairy root culture process for tetrandrine production	19
Probing the interaction of zinc oxide nanorods with human serum albumin: A spectroscopic approach	19
Reviewing critical TRPM2 variants through a structure-function lens	19
Multiple genome analytics framework: The case of all SARS-CoV-2 complete variants	19
Establishment of high-efficiency hairy root and genetic transformation system in Cynanchum stauntonii	19
Channel matters: Overcoming diffusion bottlenecks via loop engineering of LinD for enhanced isoprene production	19
Editorial Board	19
Metabolic and biotechnological insights on the analysis of the Pdh bypass and acetate production in the yeast Dekkera bruxellensis	19
Low-cost alternative for the bioproduction of bioactive phenolic compounds of callus cultures from Cereus hildmannianus (K.) Schum	19
Advancements in enzymatic biotransformation and bioactivities of rare ginsenosides: A review	19
Elucidation of the fucose metabolism of probiotic Lactobacillus rhamnosus GG by metabolomic and flux balance analyses	19
Metabolic rewiring revealed by cell-specific rate analyses from nontargeted exometabolomics during simultaneous consumption of glucose and lactic acid in a CHO fed-batch process	19
pH-dependent electrostatic interactions between enzymes and nanoparticles in Pickering emulsions – Influence on activity and droplet size	18
Improving thermostability of α-L-fucosidase from Pedobacter sp. via consensus-guided engineering and directed evolution	18
Enhanced laccase separation from fermentation medium using cryogel columns	17
Production of recombinant human type I collagen homotrimers in CHO cells and their physicochemical and functional properties	17
Analysis of population heterogeneity in CHO cells by genome-wide DNA methylation analysis and by multi-modal single-cell sequencing	17
Metabolic engineering of Schizosaccharomyces pombe for itaconic acid production	17
Using synthetic biology to improve photosynthesis for sustainable food production	17
Bioconversion for ursodeoxycholic acid using β-cyclodextrin included-chenodeoxycholic acid via immobilized cells of Xanthomonas maltophilia	17

Ternary deep eutectic solvent (T-CuCl2-EG) for lignin removal from corn straw	17
High-throughput flow cytometry-based titration of a live attenuated rotavirus vaccine	17
Weak promoters to drive selection marker expression: Improvement of cell line development process for therapeutic protein production in CHO-K1 cells	16
Expediting adenovirus titer assays via an algorithmic live-cell imaging technique	16
Microbial production of mevalonate	16
Extension of the circulatory half-life of recombinant ecallantide via albumin fusion without loss of anti-kallikrein activity	16
Efficiency and scalability in harvesting mammalian cell cultures: A scale-down approach to continuous centrifugation	16
Development of thermostable dextranase from Streptococcus mutans (SmdexTM) through in silico design employing B-factor and Cartesian-ΔΔG	16
Surface property effects in the immobilization of L-lactate oxidase on gold electrodes by self-assembled monolayers	16
Editorial Board	16
A comprehensive overview of nanotechnology in sustainable agriculture	16
Alleviation of cadmium toxicity and minimizing its accumulation in rice plants by methyl jasmonate: Performance and mechanisms	16
Thermal degradation kinetics and purification of C-phycocyanin from thermophilic and mesophilic cyanobacteria	16
Biosurfactants as microbial bioactive compounds in microbial enhanced oil recovery	16
Genetic transformation of ‘Hamlin’ and ‘Valencia’ sweet orange plants expressing the cry11A gene of Bacillus thuringiensis as an additional tool for the management of Diaphorina citri (Hemiptera: Livi	16
Enhanced activation of signaling pathway by recombinant human adiponectin from genome-edited chickens	16
Rational comparison of biohydrogen production using Clostridium species through dark fermentation during anaerobic batch processes	15
Halophilic filamentous fungi and their enzymes: Potential biotechnological applications	15
Editorial Board	15
Ozonation process causes changes in PARP-1 expression and the metabolism of NADPH in strawberry fruit during storage	15
Light intensity and spectral quality modulation for improved growth kinetics and biochemical composition of Chlamydomonas reinhardtii	15
UV-ARTP compound mutagenesis breeding improves macrolactins production of Bacillus siamensis and reveals metabolism changes by proteomic	15
Microbial production of single cell oil from biowaste-derived volatile fatty acids using a newly identified oleaginous Cyberlindnera jadinii	15
Integrating genetic assortment and molecular insights for climate-resilient breeding to unravel drought tolerance in cotton	14
Hemp tea waste-immobilized lipase for the synthesis of alkyl oleates in solvent free systems	14
Novel efficient enzymatic synthesis of the key-reaction intermediate of PET depolymerization, mono(2-hydroxyethyl terephthalate) – MHET	14
A novel directed evolution approach for co-evolution of β-glucosidase activity and organic acid tolerance	14
Enhancing secondary metabolite biosynthesis from ethnomedicinal plant Solanum nigrum L. through cytogenetically stable mass propagation, transgenic hairy root induction, and using different LED light	14
Ethanolysis of degummed soybean oil using magnetic CLEAs from Eversa® Transform	14
QTL mapping in sesame (Sesamum indicum L.): A review	14
Engineered praseodymium sulfide nanocarrier and supramolecular association of anticancer drug for effective delivery to breast cancer cells	14
Editorial Board	14
Development of a new extraction method and functional analysis of phycocyanobilin from unique filamentous cyanobacteria	14
Cd2+ tolerance and removal mechanisms of Serratia marcescens KMR-3	14
Enhanced anthraquinone biosynthesis in Damnacanthus major cells via medium optimization and fed-batch bioreactor culture	13
Dynamic regulation of ROS stress in the accumulation of L-lysine in Escherichia coli	13
Persistent low PHB accumulation during pilot-scale gas fermentation in Cupriavidus necator	13
Next level of p-phenylene diisothiocyanate-based covalent immobilization of β-D-galactosidase: Technical optimization as an application	13
Hairy roots as a biotechnological tool for medicinal plant secondary metabolites: A systematic review	13
Editorial Board	12
Construction of an E. coli cell factory for ergothioneine through SAM-cycle enhancement and pathway reconstruction	12
Genomic features of recombinant CHO clones arising from transposon-based and randomized integration	12
Editorial Board	12
Engineering Saccharomyces boulardii for cell surface display of heterologous protein	12
Priming with EDTA, IAA and Fe alleviates Pb toxicity in Trigonella Foneum graecum L. growth: Phytochemicals and secondary metabolites	12
A review on anticancer, antibacterial and photo catalytic activity of various nanoparticles synthesized by probiotics	12
Thermodynamics of microbial consortia: Enthalpies and Gibbs energies of microorganism live matter and macromolecules of E. coli, G. oxydans, P. fluorescens, S. thermophilus and P. chrysogenum	12
Cell specific nutrient feeding in perfusion mode enhances hMSC growth in stirred tank bioreactor process	12
Effect of selenium and tungsten on cell growth and metabolite production in syngas fermentation using “Clostridium autoethanogenum”	12
Impact of humanization scaffold design on the functional activity of FGFR2-targeting chicken scFvs	12
Investigation into optimizing fermentation processes to enhance uric acid degradation by probiotics	12
Enhanced molecular stability of ApxII antigen during secretion in Corynebacterium glutamicum by rational design	12
Improved biocatalytic activity of steapsin lipase in supercritical carbon dioxide medium for the synthesis of benzyl butyrate: A commercially important flavour compound	12
Pretreatment of lignocellulosic biogas substrates by filamentous fungi	12
Corrigendum to “A cheap two-step cultivation of Phaeodactylum tricornutum for increased TAG production and differential expression of TAG biosynthesis associated genes” [J. Biotechnol. 354 (2022) 53–6	12
The CRISPR Cas patent files, part 4: All back to zero, think again!	12
High specificity of MsmCAR toward 4-hydroxyvaleric acid enables efficient 1,4-pentanediol production from biomass-derived levulinic acid	12
Characterization of 3D-printed acrylonitrile butadiene styrene and polylactic acid carrier-beads for Gluconobacter oxydans immobilization	12
Progress on production of malic acid and succinic acid by industrially-important engineered microorganisms	12
Lipase-mediated alcoholysis for in situ production of ester bioaromas in licuri oil for cosmetic applications	11
Application of a novel virus-like particle platform to the development of Neisseria vaccines	11
Human beta-defensin 3-functionalized Fe/GMP nanozyme for multifunctional antimicrobial and anticancer activity against Helicobacter pylori-associated gastrointestinal cancer	11
Expression of a recombinant protein by an acetic acid bacterial host	11
Volatile organic compounds: A threat to the environment and health hazards to living organisms – A review	11
Customized design of host-independent T7 expression system (HITES) for a broad host range	11
P3HT-based organic field effect transistor for low-cost, label-free detection of immunoglobulin G	11
Optimization of fungal fermentation for the extraction of polyphenols from Flourensia cernua and its effect on cellular metabolism	11
Low-molecular-weight impurity in Poloxamer 188 responsible for atypical cell culture performance for mAb production	11
High temperature drives torularhodin-dominant carotenoid overaccumulation in Rhodosporidiobolus odoratus XQR via coordinated transcriptomic–metabolomic reprogramming	11
Editorial Board	11
Digital holographic microscopy is suitable for lipid accumulation analysis in single cells of Yarrowia lipolytica	11
Optimizing mycelial protein yield in Pleurotus djamor via ARTP mutagenesis and hybridization strategies	11
Production and purification of recombinant long protein isoforms of FGF11 subfamily	11
Harnessing nature's catalysts: Advances in enzymatic alkene cleavage	11
Editorial Board	11
Editorial Board	10
Immobilization of aldoxime dehydratases on metal affinity resins and use of the immobilized catalysts for the synthesis of nitriles important in fragrance industry	10
Evaluating the role of trypsin in silk degumming: An in silico approach	10
Comparison of plant biostimulating properties of Chlorella sorokiniana biomass produced in batch and semi-continuous systems supplemented with pig manure or acetate	10
Efficient expression and functional verification of recombinant human type Ⅲ collagen in CHO cells	10

Virion-surface display of a chimeric immunoglobulin Fc domain facilitating uptake by antigen-presenting cells	10
Reduced production of Ethyl Carbamate in wine by regulating the accumulation of arginine in Saccharomyces cerevisiae	10
Development of a 10 g/L process for a difficult-to-express multispecific antibody format using a holistic process development approach	10
High-concentration Mg2+ stress improves L-lactic acid biosynthesis of Bacillus coagulans revealed by combined analysis of transcriptome and metabolome	10
Increasing the chiral purity of cellulosic L-lactic acid by D-Lactate oxidase-catalyzed oxidation in engineered lactic acid bacterium Pediococcus acidilactici	10
Enhancing the amination activity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum by modifying the crucial residue His154 for deamination	10
A highly efficient mixed strain fermentation strategy to produce 11α-Hydroxyandrost-4-ene-3,17-dione from phytosterols	10
Modular engineering of the doxorubicin biosynthetic gene cluster based on component functional clustering in Streptomyces	10
Bioeffects of static magnetic fields on the growth and metabolites of C. pyrenoidosa and T. obliquus	10
A pump-free microfluidic co-culture system for investigating NK cell-tumor spheroid interactions in flow conditions	10
Advancement on mixed microalgal-bacterial cultivation systems for nitrogen and phosphorus recoveries from wastewater to promote sustainable bioeconomy	10
Synergistic interaction of AaMYC2 and AaMYC2-LIKE enhances artemisinin production in Artemisia annua L.	10
Investigation of anti-adherence and antimicrobial properties of prodigiosin-functionalized bacterial cellulose membrane for biomedical applications	10
Cell-based shear stress sensor for bioprocessing	10
Molecular biomarkers identification and applications in CHO bioprocessing	10
High yield secretion of human erythropoietin from tobacco cells for ex vivo differentiation of hematopoietic stem cells towards red blood cells	9
RNA-based detection of genetically modified plants via current-voltage characteristic measurement	9
System-wide analysis of groundnut's salinity resilience: Integrating plant-cell interactions with environmental stress dynamics through cutting-edge transcriptomics	9
Impact of liquid and solid-state cultures on hemoglobin production and oxidative state in Saccharomyces cerevisiae	9
Optical, structural, and antifungal properties of nanosilver borate bioactive glass synthesized using gamma rays on the survival of Candida albicans and Candida tropicalis	9
Bone marrow-derived dendritic cells play a role in attenuating inflammation on Bothrops jararacussu venom muscle damage	9
Glycolate as alternative carbon source for Escherichia coli	9
Indole-3-butyric acid mediated growth and biochemical enhancement in three Selenastracean green microalgae under limited supply of nitrogen source	9
Optimizing bio-vanillin synthesis from ferulic acid via Pediococcus acidilactici: A systematic approach to process enhancement and yield maximization	9
Endophyte-assisted non-host plant Tillandsia brachycaulos enhance indoor formaldehyde removal	9
Editorial Board	9
De novo biosynthesis of lavandulol and lavandulyl acetate in Escherichia coli	9
Sortase E-mediated site-specific immobilization of green fluorescent protein and xylose dehydrogenase on gold nanoparticles	9
Engineered L-phenylserine aldolase enhances L-norvaline synthesis within an enzyme cascade	9
Engineering adaptive alleles for Escherichia coli growth on sucrose using the EasyGuide CRISPR system	9
Engineering the cell wall reactive groups of Plant Growth Promoting Rhizobacteria by culture strategy for heavy metal removal	9
Microalgae as a potential therapeutic drug candidate for neurodegenerative diseases	9
Fuel characterization, engine performance characteristics and emissions analysis of different mustard seed biodiesel: An overview	9
CRISPR-based precise methylation of specific FUT8 promoter regions allows isolation of CHO cells with a fine-tuned glycoprofile	9
Unlocking new frontiers in healthcare: The impact of nano-optical biosensors on personalized medical diagnostics	9
Streamlined in vitro screening system of synthetic signal peptides in Chinese hamster ovary cells for therapeutic protein production	8
Efficient multiplex CRISPR/Cpf1 (Cas12a) genome editing system in Aspergillus aculeatus TBRC 277	8
Interferon inhibitors increase rAAV production in HEK293 cells	8
Editorial Board	8
A chitosan-integrated antibacterial protein composite nanocomplex derived from barnacle cement and spider silk	8
Metabolic engineering and high-cell-density fermentation of Corynebacterium glutamicum to improve isopropanol production	8
Identification and characterization of anaerobically activated promoters in Escherichia coli	8
Metabolic engineering of carotenoid biosynthesis in Yarrowia lipolytica	8
Structure-guided engineering of 4-coumarate: CoA ligase for efficient production of rosmarinic acid in Saccharomyces cerevisiae	8
Ectoine production from a novel bacterial strain and high-purity purification with a cost-effective and single-step method	8
Immobilization of glycosyltransferase into a hydrophilic metal-organic framework for efficient biosynthesis of chondroitin sulfate	8
Regulatory non-coding RNA: The core defense mechanism against plant pathogens	8
Multi-parameter process optimization for high yield AAV2 vector production using scale-down multi-parallel bioreactor systems and high-throughput analytical tools	8
Enhanced prokaryotic expression, purification, and biological activities of human keratinocyte growth factor	8
Advances in photonic crystal hydrogels for biomedical research: A review	8
Biotechnological parameters of cultivation of mycorrhizal fungi Cortinarius caperatus and Laccaria bicolor	8
Editorial Board	8
Metabolic engineering of Escherichia coli for seleno-methylselenocysteine production	8
N-region of Cry1Ia: A novel fusion tag for Escherichia coli and Pichia pastoris	8
Uncovering gene expression signatures and diagnostic – Biomarkers in hepatocellular carcinoma through multinomial logistic regression analysis	8