Trends in Biotechnology

Papers
(The TQCC of Trends in Biotechnology is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Advisory Board and Contents249
Subscription and Copyright information248
Auricular repair: symphony between scaffolds and stem cells230
Electronic plants: the future of agriculture and urban ecosystems?175
Engineering biology approaches to modulate bacterial biofilms142
Smart Nucleic Acids as Future Therapeutics141
Potency Meets Precision in Nano-optimized Chemotherapeutics141
Vector-free intra-airway in vivo epigenetic editing127
Healing wounds with plasma-activated hydrogel therapy123
SynMADE: synthetic microbiota across diverse ecosystems119
Phytohormones: novel strategy for removing emerging contaminants and recovering resources118
Scalable tissue biofabrication via perfusable hollow fiber arrays for cultured meat applications116
Bridging the path to multiplexed molecular diagnostics113
(R)evolution-on-a-chip104
Designing Artificial Cells towards a New Generation of Biosensors97
Unlocking the potential of stem-cell-derived ‘synthetic’ embryo models94
The green revolution of food waste upcycling to produce polyhydroxyalkanoates92
Vibrio natriegens as a host for rapid biotechnology90
Food Waste: A Promising Source of Sustainable Biohydrogen Fuel89
Microalgae: a revolution for salt-affected soil remediation84
Enzyme discovery and engineering for sustainable plastic recycling84
Smart materials: rational design in biosystems via artificial intelligence83
Manipulating immune activity of macrophages: a materials and mechanics perspective82
Analyzing and understanding the robustness of bioprocesses79
Prime editing: advances and therapeutic applications77
Advisory Board and Contents74
Advisory Board and Contents73
Subscription and Copyright information72
Can protein expression be ‘solved’?71
Subscription and Copyright information71
Integrating bicarbonate-based microalgal production with alkaline sewage for ocean negative carbon emissions70
Machine learning to predict de novo protein–protein interactions70
Manufacturing innovation to drive down cell therapy costs68
Subscription and Copyright information68
Beyond waste: understanding urine’s potential in precision medicine68
Multiscale models quantifying yeast physiology: towards a whole-cell model67
Printhead on a chip: empowering droplet-based bioprinting with microfluidics67
Efficient genome-editing tools to engineer the recalcitrant non-model industrial microorganism Zymomonas mobilis67
Next-generation digital biomarkers: continuous molecular health monitoring using wearable devices66
UFSC Biotech Network: a transdisciplinary platform for biotechnology innovation in Brazil66
The GPS for drug development: navigating with evidence from human populations66
A high-performance protein preparation approach in a single column-free step63
Emerging strategies to develop novel genetically encoded biosensors63
Ocular RNA nanomedicine: engineered delivery nanoplatforms in treating eye diseases62
Translational organoid technology – the convergence of chemical, mechanical, and computational biology62
Engineering the mangrove soil microbiome for selection of polyethylene terephthalate-transforming bacterial consortia61
Machine learning in bioprocess development: from promise to practice60
Extended human lymph node explants for evaluation of adaptive immunity60
Mini-bones: miniaturized bone in vitro models59
Towards biomanufacturing of cultured meat58
Molecular design of microalgae as sustainable cell factories57
Subscription and Copyright information56
3D printing of heart valves56
Trends in sustainable single-cell protein from non-grain feedstocks55
Engineered bacterial therapeutics with material solutions55
Sebum analysis as an advantageous source of biomolecular information55
Advisory Board and Contents54
Advisory Board and Contents54
A new chapter for anti-idiotypes in low molecular weight compound immunoassays54
Biosafety and biosecurity: treading China’s synbio tightrope53
3D extrusion bioprinting: rational bioink design and advanced fabrication techniques52
The morally disruptive future of reprogenetic enhancement technologies52
Improving awareness, understanding, and enforcement of responsibilities and regulations in Blue Biotechnology51
Frog ‘N’ Roll: novel synthetic peptides selective against Gram-negative pathogens51
Building biomaterials through genetic code expansion50
Dynamic plasmid copy number control for synthetic biology50
The LEGO® brick road to open science and biotechnology49
Dynamically regulating metabolic fluxes with synthetic metabolons48
Next-generation 3D-printed nutritious food derived from waste plastic and biomass47
Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy47
Harnessing Streptomyces–plant interactions for agricultural natural product discovery47
Ethical challenges with 3D bioprinted tissues and organs46
Multienzymatic synthesis of nylon monomers from vegetable oils46
Spatial omics for accelerating plant research and crop improvement44
Emerging supramolecular and living materials in oral medicine44
Estimating environmental impacts of early-stage bioprocesses43
Bioprinted, spatially defined breast tumor microenvironment models of intratumoral heterogeneity and drug resistance43
Using synthetic biology to express nitrogenase biosynthesis pathway in rice and to overcome barriers of nitrogenase instability in plant cytosol43
Bringing the next biotechnologies to life42
Synthetic biology for plant genetic engineering and molecular farming42
From academia to real-life biotech: ‘It takes a village’41
Rethinking techno-moral disruption in bioethics, society, and justice41
Design principles for engineering light-controlled antibodies41
Rapid selection of transgenic mammalian cells via diphtheria toxin resistance40
Academic entrepreneurship: promise and perils40
Molecular engineering of insulin for recombinant expression in yeast39
Non-sterile cultivation of oleaginous organisms39
Protein–glycan engineering in vaccine design: merging immune mechanisms with biotechnological innovation39
Advances in induced anhydrobiosis for cell and gamete storage38
Next-generation industrial biotechnology for low-cost mass production of PHA38
Advanced strategies for enzyme–electrode interfacing in bioelectrocatalytic systems38
Microbial electrosynthesis: opportunities for microbial pure cultures38
Harnessing lactic acid bacteria in synthetic microbial consortia38
Bioengineering human placentas: social implications of an advancing field37
Biotechnological approaches for producing natural pigments in yeasts37
Advisory Board and Contents37
Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials36
Long-offset paired nicking-based efficient and precise strategy for in vivo targeted insertion36
Robots with a human touch36
HHV-6 and HHV-7 reactivation in allogeneic CAR-T cell therapy36
Computationally guided genome rewiring of Escherichia coli and its application for nanopolyethylene terephthalate (PET) biodegradation and upcycling36
Advisory Board and Contents36
Merging automation and fundamental discovery into the design–build–test–learn cycle of nontraditional microbes35
Engineering large-scale hiPSC-derived vessel-integrated muscle-like lattices for enhanced volumetric muscle regeneration35
How transdisciplinarity can help biotech-driven biodiversity research35
Marine-derived bioactive materials as antibiofilm and antivirulence agents35
Apart, Together: Reflections on the COVID-19 Pandemic34
Bioprocessing technology of muscle stem cells: implications for cultured meat34
Engineering Minds? Ethical Considerations on Biotechnological Approaches to Mental Health, Well-Being, and Human Flourishing34
Distillation for in situ recovery of volatile fermentation products34
Efficient and sustained photosynthetic hydrogen production by algae under high light intensity33
Exploring standards for multicellular mammalian synthetic biology33
Transforming undergraduate laboratory courses with interlinked real-world challenges33
Biotechnology applications of proteins functionalized with DNA oligonucleotides33
From Innovation to Application: Bridging the Valley of Death in Industrial Biotechnology32
Light-induced programmable solid–liquid phase transition of biomolecular condensates for improved biosynthesis32
CRISPR-Cas12c: a noncleaving DNA binder with minimal PAM requirement32
Product-driven high-throughput screening of industrial filamentous actinomycetes32
Harnessing synthetic biology to develop novel psychedelic therapies32
Novel delivery systems for controlled release of bacterial therapeutics32
An epigenetic regulator synergizes with alphavirus-mediated gene therapy via biomimetic delivery for enhanced cancer therapy32
Welfare impacts of China's regulatory change toward genome-edited crops32
CRISPR/Cas-based personal glucose meters for nucleic acid detection32
Enzyme Catalyst Engineering toward the Integration of Biocatalysis and Chemocatalysis31
Engineered RNA nanostructures for scalable and efficient RNAi-based pesticides31
Organ-on-a-chip systems for modeling tumor and normal tissue microenvironments in radiotherapy research31
pHNRhCas9NG, single expression cassette-based dual-component dual-transcription unit CRISPR/Cas9 system for plant genome editing31
Immunostimulation in experimental gas plasma therapy for breast cancer30
Systematic development of a highly efficient cell factory for 5-aminolevulinic acid production30
Harnessing the microbial world for human benefit30
RNA and nanocarriers: next generation drug and delivery platform take center stage30
Chips, guts, and gas: unraveling volatile microbial mysteries in real time!30
Functionalization of Cellular Membranes with DNA Nanotechnology29
Synthetic transcription factor engineering for cell and gene therapy29
Prime editor integrase systems boost targeted DNA insertion and beyond29
Gas plasma technology mediates deep tissue and anticancer events independently of hydrogen peroxide29
OMEGA-guided DNA polymerases enable random mutagenesis in a tunable window29
Dynamic anaerobic digestion-based biorefineries for on-demand renewable energy and bioproducts in a circular bioeconomy29
Advancing plant gene activation with CRISPR-Act3.028
Phase-separated biomolecular condensates for biocatalysis27
Evading and overcoming AAV neutralization in gene therapy27
Application of bacterial extracellular vesicles in gastrointestinal diseases27
Emerging Applications of 3D Printing in Biomanufacturing27
Editing a healthier future in plants26
Subscription and Copyright information26
Advisory Board and Contents26
Oxygen-Releasing Biomaterials: Current Challenges and Future Applications26
Subscription and Copyright information26
Artificial intelligence in biomaterials: a call for unified biocompatibility standards25
Human bone marrow organoids: emerging progress but persisting challenges25
Intervertebral disc-on-a-chip: a precision engineered toolbox for low back pain studies25
Advancing wheat breeding using rye: a key contribution to wheat breeding history25
Yeast-based screening platforms to understand and improve human health25
The lignocellulosic biorefinery concept is sound: a commentary on Zhao et al.25
Power-to-vitamins: producing folate (vitamin B9) from renewable electric power and CO2 with a microbial protein system25
Advancements and regulations of biomanufacturing cell-based cartilage repair therapies25
Blockchain as a frontier in biotechnology and bioenergy applications25
Shaping the future US bioeconomy through safety, security, sustainability, and social responsibility25
Prokaryotic Argonautes for in vivo biotechnology and molecular diagnostics25
The biotechnology revolution in textile dyeing24
Large language model for knowledge synthesis and AI-enhanced biomanufacturing24
Nondestructive testing of native and tissue-engineered medical products: adding numbers to pictures24
Robustness: linking strain design to viable bioprocesses24
Framing synthetic biology as an innovation-driven market24
Sensors in blockchain24
Escherichia coli selection strains for growth-coupled metabolic engineering23
Hydrogen production in microbial electrolysis cells with biocathodes23
Next-generation electroactive biomaterials-integrated bioelectronics for advanced healthcare management23
Comparison of CRISPR/Cas and Argonaute for nucleic acid tests23
Bringing carbon to life via one-carbon metabolism23
Chimeric antigen receptor therapy meets mRNA technology23
Programmable embedded bioprinting for one-step manufacturing of arterial models with customized contractile and metabolic functions23
Navigating microalgae under dynamic CO2 for waste-to-energy conversion22
Advisory Board and Contents22
Synthetic biology for Taxol biosynthesis and sustainable production22
Subscription and Copyright information22
Cellular reprogramming and the rise of rejuvenation biotech22
Media representations of synthetic biology in China22
Chairside live biotherapeutic hydrogel for comprehensive periodontitis therapy22
Subscription and Copyright information22
Insights on cisgenic plants with durable disease resistance under the European Green Deal21
Osmotic-controlled release oral tablets: technology and functional insights21
Subscription and Copyright information21
Towards machine learning for hydrogel drug delivery systems21
Strengthening the competitiveness of EU in vitro biotechnologies21
Point-of-care detection devices for wound care and monitoring21
Large-scale manufacturing of human gallbladder epithelial cell products and derived hepatocytes via a chemically defined approach21
Pollutant degradation in saline wastewater using synthetic biology21
One-pot diagnostic methods based on CRISPR/Cas and Argonaute nucleases: strategies and perspectives21
Subscription and Copyright information21
Robotic micromotors transforming oral drug administration20
Organs-on-chips: a decade of innovation20
Untethered: using remote magnetic fields for regenerative medicine20
CarveAdornCurate: a versatile cloud-based platform for constructing multiscale metabolic models20
Additive Manufacturing Tools to Improve the Performance of Chromatographic Approaches20
Engineering next-generation oxygen-generating scaffolds to enhance bone regeneration20
A forward-thinking biocompatibility assessment: drafting future considerations now20
Efficiency and process development for microbial biomass production using oxic bioelectrosynthesis20
A ventilated perfused lung model platform to dissect the response of the lungs to viral infection20
Microbial cellulose production using ocean water: sustainable and cost-effective?19
Validation Is Not Verification: Precise Terminology and Scientific Methods in Bioprocess Modeling19
Protein–nucleic acid thermodynamic databases for specific uses19
Gene drive in species complexes: defining target organisms19
Driving towards digital biomanufacturing by CHO genome-scale models19
A pathway to improve seaweed aquaculture through microbiota manipulation19
Advisory Board and Contents18
Improving plant C-to-G base editors with a cold-adapted glycosylase and TadA-8e variants18
Agricultural biotechnology for sustainable food security18
Spatial -omics technologies: the new enterprise in 3D breast cancer models18
Design of biomass-based renewable materials for environmental remediation18
Quality by Design for enabling RNA platform production processes18
Thermodynamic database supports deciphering protein–nucleic acid interactions18
Advances in ultrahigh-throughput screening technologies for protein evolution18
Biosensors for healthcare: current and future perspectives18
TRYing to evaluate production costs in microbial biotechnology18
Subscription and Copyright information18
Ethics and engagement: steering China’s synbio future18
Innovation trends in industrial biotechnology18
Harnessing microbes to pioneer environmental biophotoelectrochemistry18
EccDNA in plant-stress and biotechnological solutions in agriculture18
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