Trends in Biotechnology

Papers
(The TQCC of Trends in Biotechnology is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Unlocking the potential of stem-cell-derived ‘synthetic’ embryo models251
Advisory Board and Contents220
Electronic plants: the future of agriculture and urban ecosystems?217
(R)evolution-on-a-chip207
Human Blood–Brain Barrier on a Chip: Featuring Unique Multicellular Cooperation in Pathophysiology206
Smart Nucleic Acids as Future Therapeutics166
Subscription and Copyright information136
Engineering biology approaches to modulate bacterial biofilms111
Potency Meets Precision in Nano-optimized Chemotherapeutics109
Designing Artificial Cells towards a New Generation of Biosensors108
SynMADE: synthetic microbiota across diverse ecosystems106
Does RNAi-Based Technology Fit within EU Sustainability Goals?104
Scalable tissue biofabrication via perfusable hollow fiber arrays for cultured meat applications103
The green revolution of food waste upcycling to produce polyhydroxyalkanoates102
Microalgae: a revolution for salt-affected soil remediation97
Phytohormones: novel strategy for removing emerging contaminants and recovering resources93
Healing wounds with plasma-activated hydrogel therapy92
Smart materials: rational design in biosystems via artificial intelligence88
Analyzing and understanding the robustness of bioprocesses88
Enzyme discovery and engineering for sustainable plastic recycling87
Manipulating immune activity of macrophages: a materials and mechanics perspective85
Vibrio natriegens as a host for rapid biotechnology77
Prime editing: advances and therapeutic applications76
Food Waste: A Promising Source of Sustainable Biohydrogen Fuel76
Advisory Board and Contents74
Advisory Board and Contents73
Subscription and Copyright information72
Subscription and Copyright information72
Translational organoid technology – the convergence of chemical, mechanical, and computational biology71
Towards biomanufacturing of cultured meat71
Beyond waste: understanding urine’s potential in precision medicine71
Printhead on a chip: empowering droplet-based bioprinting with microfluidics70
Multiscale models quantifying yeast physiology: towards a whole-cell model70
Manufacturing innovation to drive down cell therapy costs67
The GPS for drug development: navigating with evidence from human populations67
Ocular RNA nanomedicine: engineered delivery nanoplatforms in treating eye diseases65
Mini-bones: miniaturized bone in vitro models64
Next-generation digital biomarkers: continuous molecular health monitoring using wearable devices63
A high-performance protein preparation approach in a single column-free step63
Efficient genome-editing tools to engineer the recalcitrant non-model industrial microorganism Zymomonas mobilis63
Integrating bicarbonate-based microalgal production with alkaline sewage for ocean negative carbon emissions61
Machine learning in bioprocess development: from promise to practice61
Engineering the mangrove soil microbiome for selection of polyethylene terephthalate-transforming bacterial consortia60
Emerging supramolecular and living materials in oral medicine60
Molecular design of microalgae as sustainable cell factories60
Subscription and Copyright information60
Engineered Living Materials: Taxonomies and Emerging Trends60
The LEGO® brick road to open science and biotechnology57
Multienzymatic synthesis of nylon monomers from vegetable oils57
Using synthetic biology to express nitrogenase biosynthesis pathway in rice and to overcome barriers of nitrogenase instability in plant cytosol57
Spatial omics for accelerating plant research and crop improvement56
The morally disruptive future of reprogenetic enhancement technologies56
Dynamically regulating metabolic fluxes with synthetic metabolons55
3D printing of heart valves55
Advisory Board and Contents54
Engineered bacterial therapeutics with material solutions54
A new chapter for anti-idiotypes in low molecular weight compound immunoassays53
Next-generation 3D-printed nutritious food derived from waste plastic and biomass53
Advisory Board and Contents53
Improving awareness, understanding, and enforcement of responsibilities and regulations in Blue Biotechnology52
Building biomaterials through genetic code expansion50
Biosafety and biosecurity: treading China’s synbio tightrope50
Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy50
Ethical challenges with 3D bioprinted tissues and organs50
Bioprinted, spatially defined breast tumor microenvironment models of intratumoral heterogeneity and drug resistance49
Dynamic plasmid copy number control for synthetic biology49
Sebum analysis as an advantageous source of biomolecular information49
Synthetic biology for plant genetic engineering and molecular farming49
Bringing the next biotechnologies to life48
Estimating environmental impacts of early-stage bioprocesses48
From academia to real-life biotech: ‘It takes a village’47
Molecular engineering of insulin for recombinant expression in yeast46
Advances in induced anhydrobiosis for cell and gamete storage46
Design principles for engineering light-controlled antibodies45
Rethinking techno-moral disruption in bioethics, society, and justice44
Harnessing lactic acid bacteria in synthetic microbial consortia44
Academic entrepreneurship: promise and perils44
Advanced strategies for enzyme–electrode interfacing in bioelectrocatalytic systems43
Next-generation industrial biotechnology for low-cost mass production of PHA43
Building Organs Using Tissue-Specific Microenvironments: Perspectives from a Bioprosthetic Ovary43
Microbial electrosynthesis: opportunities for microbial pure cultures42
Non-sterile cultivation of oleaginous organisms42
Biotechnological approaches for producing natural pigments in yeasts42
Robots with a human touch41
Advisory Board and Contents41
Modeling the Human Body on Microfluidic Chips40
Long-offset paired nicking-based efficient and precise strategy for in vivo targeted insertion40
Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials40
Bioengineering human placentas: social implications of an advancing field40
Merging automation and fundamental discovery into the design–build–test–learn cycle of nontraditional microbes40
Engineering large-scale hiPSC-derived vessel-integrated muscle-like lattices for enhanced volumetric muscle regeneration40
Marine-derived bioactive materials as antibiofilm and antivirulence agents39
HHV-6 and HHV-7 reactivation in allogeneic CAR-T cell therapy39
Bioprocessing technology of muscle stem cells: implications for cultured meat38
Gallium-Based Liquid Metal Particles for Therapeutics38
CRISPR-Cas12c: a noncleaving DNA binder with minimal PAM requirement36
An epigenetic regulator synergizes with alphavirus-mediated gene therapy via biomimetic delivery for enhanced cancer therapy36
Apart, Together: Reflections on the COVID-19 Pandemic36
Advisory Board and Contents36
Biotechnology applications of proteins functionalized with DNA oligonucleotides35
Distillation for in situ recovery of volatile fermentation products35
Engineering Minds? Ethical Considerations on Biotechnological Approaches to Mental Health, Well-Being, and Human Flourishing35
Transforming undergraduate laboratory courses with interlinked real-world challenges35
Light-induced programmable solid–liquid phase transition of biomolecular condensates for improved biosynthesis34
Harnessing synthetic biology to develop novel psychedelic therapies34
SWATH-MS-Based Proteomics: Strategies and Applications in Plants34
Overcoming Challenges in Expressing Iron–Sulfur Enzymes in Yeast34
Exploring standards for multicellular mammalian synthetic biology33
pHNRhCas9NG, single expression cassette-based dual-component dual-transcription unit CRISPR/Cas9 system for plant genome editing32
Product-driven high-throughput screening of industrial filamentous actinomycetes32
Enzyme Catalyst Engineering toward the Integration of Biocatalysis and Chemocatalysis32
Novel delivery systems for controlled release of bacterial therapeutics32
In Situ 3D Printing: Opportunities with Silk Inks31
From Innovation to Application: Bridging the Valley of Death in Industrial Biotechnology31
RNA and nanocarriers: next generation drug and delivery platform take center stage31
OMEGA-guided DNA polymerases enable random mutagenesis in a tunable window30
Prime editor integrase systems boost targeted DNA insertion and beyond30
Harnessing the microbial world for human benefit30
Immunostimulation in experimental gas plasma therapy for breast cancer30
Emerging Applications of 3D Printing in Biomanufacturing30
Chips, guts, and gas: unraveling volatile microbial mysteries in real time!30
Phase-separated biomolecular condensates for biocatalysis29
Advancing plant gene activation with CRISPR-Act3.029
Oxygen-Releasing Biomaterials: Current Challenges and Future Applications29
Systematic development of a highly efficient cell factory for 5-aminolevulinic acid production29
Evading and overcoming AAV neutralization in gene therapy29
Advisory Board and Contents29
Functionalization of Cellular Membranes with DNA Nanotechnology29
Synthetic transcription factor engineering for cell and gene therapy29
Dynamic anaerobic digestion-based biorefineries for on-demand renewable energy and bioproducts in a circular bioeconomy29
Subscription and Copyright information28
Subscription and Copyright information28
Large language model for knowledge synthesis and AI-enhanced biomanufacturing28
Editing a healthier future in plants28
Nondestructive testing of native and tissue-engineered medical products: adding numbers to pictures27
Blockchain as a frontier in biotechnology and bioenergy applications27
The lignocellulosic biorefinery concept is sound: a commentary on Zhao et al.27
Framing synthetic biology as an innovation-driven market27
Advancements and regulations of biomanufacturing cell-based cartilage repair therapies27
Artificial intelligence in biomaterials: a call for unified biocompatibility standards26
Sensors in blockchain26
Intervertebral disc-on-a-chip: a precision engineered toolbox for low back pain studies26
Bringing carbon to life via one-carbon metabolism26
Programmable embedded bioprinting for one-step manufacturing of arterial models with customized contractile and metabolic functions26
Yeast-based screening platforms to understand and improve human health26
Advancing wheat breeding using rye: a key contribution to wheat breeding history26
Shaping the future US bioeconomy through safety, security, sustainability, and social responsibility25
Hydrogen production in microbial electrolysis cells with biocathodes25
Robustness: linking strain design to viable bioprocesses25
Power-to-vitamins: producing folate (vitamin B9) from renewable electric power and CO2 with a microbial protein system25
Comparison of CRISPR/Cas and Argonaute for nucleic acid tests25
Chimeric antigen receptor therapy meets mRNA technology25
The biotechnology revolution in textile dyeing25
Prokaryotic Argonautes for in vivo biotechnology and molecular diagnostics25
Subscription and Copyright information24
Advisory Board and Contents24
The File Drawer Problem in Nanomedicine24
Subscription and Copyright information24
Media representations of synthetic biology in China23
Synthetic biology for Taxol biosynthesis and sustainable production23
Understanding and Assisting Reproduction in Wildlife Species Using Microfluidics23
From 3D Back to 2D Monolayer Stomach Organoids-on-a-Chip23
Towards machine learning for hydrogel drug delivery systems22
One-pot diagnostic methods based on CRISPR/Cas and Argonaute nucleases: strategies and perspectives22
Extracellular Vesicles in Cardiac Regeneration: Potential Applications for Tissues-on-a-Chip22
Insights on cisgenic plants with durable disease resistance under the European Green Deal22
Cellular reprogramming and the rise of rejuvenation biotech22
Learning from Nature to Expand the Genetic Code22
Osmotic-controlled release oral tablets: technology and functional insights22
Chairside live biotherapeutic hydrogel for comprehensive periodontitis therapy22
Subscription and Copyright information21
Subscription and Copyright information21
Driving towards digital biomanufacturing by CHO genome-scale models21
Point-of-care detection devices for wound care and monitoring21
Spatial -omics technologies: the new enterprise in 3D breast cancer models20
Robotic micromotors transforming oral drug administration20
Gene drive in species complexes: defining target organisms20
A forward-thinking biocompatibility assessment: drafting future considerations now20
TRYing to evaluate production costs in microbial biotechnology20
Advances in ultrahigh-throughput screening technologies for protein evolution20
Design of biomass-based renewable materials for environmental remediation20
EccDNA in plant-stress and biotechnological solutions in agriculture20
Agricultural biotechnology for sustainable food security20
Innovation trends in industrial biotechnology19
Additive Manufacturing Tools to Improve the Performance of Chromatographic Approaches19
Engineering next-generation oxygen-generating scaffolds to enhance bone regeneration19
Harnessing microbes to pioneer environmental biophotoelectrochemistry19
Protein–nucleic acid thermodynamic databases for specific uses19
CarveAdornCurate: a versatile cloud-based platform for constructing multiscale metabolic models19
A pathway to improve seaweed aquaculture through microbiota manipulation19
Validation Is Not Verification: Precise Terminology and Scientific Methods in Bioprocess Modeling19
Untethered: using remote magnetic fields for regenerative medicine19
Enhancing Biopolymer Hydrogel Functionality through Interpenetrating Networks18
Biosensors for healthcare: current and future perspectives18
Subscription and Copyright information18
Quality by Design for enabling RNA platform production processes18
Organs-on-chips: a decade of innovation18
Efficiency and process development for microbial biomass production using oxic bioelectrosynthesis18
A ventilated perfused lung model platform to dissect the response of the lungs to viral infection18
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