Trends in Biotechnology

Article	Citations
Unlocking the potential of stem-cell-derived ‘synthetic’ embryo models	251
Advisory Board and Contents	220
Electronic plants: the future of agriculture and urban ecosystems?	217
(R)evolution-on-a-chip	207
Human Blood–Brain Barrier on a Chip: Featuring Unique Multicellular Cooperation in Pathophysiology	206
Smart Nucleic Acids as Future Therapeutics	166
Subscription and Copyright information	136
Engineering biology approaches to modulate bacterial biofilms	111
Potency Meets Precision in Nano-optimized Chemotherapeutics	109
Designing Artificial Cells towards a New Generation of Biosensors	108
SynMADE: synthetic microbiota across diverse ecosystems	106
Does RNAi-Based Technology Fit within EU Sustainability Goals?	104
Scalable tissue biofabrication via perfusable hollow fiber arrays for cultured meat applications	103
The green revolution of food waste upcycling to produce polyhydroxyalkanoates	102
Microalgae: a revolution for salt-affected soil remediation	97
Phytohormones: novel strategy for removing emerging contaminants and recovering resources	93
Healing wounds with plasma-activated hydrogel therapy	92
Smart materials: rational design in biosystems via artificial intelligence	88
Analyzing and understanding the robustness of bioprocesses	88
Enzyme discovery and engineering for sustainable plastic recycling	87
Manipulating immune activity of macrophages: a materials and mechanics perspective	85
Vibrio natriegens as a host for rapid biotechnology	77
Food Waste: A Promising Source of Sustainable Biohydrogen Fuel	76
Prime editing: advances and therapeutic applications	76
Advisory Board and Contents	74

Advisory Board and Contents	73
Subscription and Copyright information	72
Subscription and Copyright information	72
Towards biomanufacturing of cultured meat	71
Beyond waste: understanding urine’s potential in precision medicine	71
Translational organoid technology – the convergence of chemical, mechanical, and computational biology	71
Multiscale models quantifying yeast physiology: towards a whole-cell model	70
Printhead on a chip: empowering droplet-based bioprinting with microfluidics	70
Manufacturing innovation to drive down cell therapy costs	67
The GPS for drug development: navigating with evidence from human populations	67
Ocular RNA nanomedicine: engineered delivery nanoplatforms in treating eye diseases	65
Mini-bones: miniaturized bone in vitro models	64
A high-performance protein preparation approach in a single column-free step	63
Efficient genome-editing tools to engineer the recalcitrant non-model industrial microorganism Zymomonas mobilis	63
Next-generation digital biomarkers: continuous molecular health monitoring using wearable devices	63
Machine learning in bioprocess development: from promise to practice	61
Integrating bicarbonate-based microalgal production with alkaline sewage for ocean negative carbon emissions	61
Subscription and Copyright information	60
Engineered Living Materials: Taxonomies and Emerging Trends	60
Engineering the mangrove soil microbiome for selection of polyethylene terephthalate-transforming bacterial consortia	60
Emerging supramolecular and living materials in oral medicine	60
Molecular design of microalgae as sustainable cell factories	60
Using synthetic biology to express nitrogenase biosynthesis pathway in rice and to overcome barriers of nitrogenase instability in plant cytosol	57
The LEGO® brick road to open science and biotechnology	57
Multienzymatic synthesis of nylon monomers from vegetable oils	57
The morally disruptive future of reprogenetic enhancement technologies	56
Spatial omics for accelerating plant research and crop improvement	56
Dynamically regulating metabolic fluxes with synthetic metabolons	55
3D printing of heart valves	55
Engineered bacterial therapeutics with material solutions	54
Advisory Board and Contents	54
Advisory Board and Contents	53
A new chapter for anti-idiotypes in low molecular weight compound immunoassays	53
Next-generation 3D-printed nutritious food derived from waste plastic and biomass	53
Improving awareness, understanding, and enforcement of responsibilities and regulations in Blue Biotechnology	52
Biosafety and biosecurity: treading China’s synbio tightrope	50
Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy	50
Ethical challenges with 3D bioprinted tissues and organs	50
Building biomaterials through genetic code expansion	50
Sebum analysis as an advantageous source of biomolecular information	49
Synthetic biology for plant genetic engineering and molecular farming	49
Bioprinted, spatially defined breast tumor microenvironment models of intratumoral heterogeneity and drug resistance	49
Dynamic plasmid copy number control for synthetic biology	49
Bringing the next biotechnologies to life	48
Estimating environmental impacts of early-stage bioprocesses	48
From academia to real-life biotech: ‘It takes a village’	47
Molecular engineering of insulin for recombinant expression in yeast	46
Advances in induced anhydrobiosis for cell and gamete storage	46
Design principles for engineering light-controlled antibodies	45
Academic entrepreneurship: promise and perils	44

Rethinking techno-moral disruption in bioethics, society, and justice	44
Harnessing lactic acid bacteria in synthetic microbial consortia	44
Building Organs Using Tissue-Specific Microenvironments: Perspectives from a Bioprosthetic Ovary	43
Advanced strategies for enzyme–electrode interfacing in bioelectrocatalytic systems	43
Next-generation industrial biotechnology for low-cost mass production of PHA	43
Biotechnological approaches for producing natural pigments in yeasts	42
Microbial electrosynthesis: opportunities for microbial pure cultures	42
Non-sterile cultivation of oleaginous organisms	42
Advisory Board and Contents	41
Robots with a human touch	41
Engineering large-scale hiPSC-derived vessel-integrated muscle-like lattices for enhanced volumetric muscle regeneration	40
Merging automation and fundamental discovery into the design–build–test–learn cycle of nontraditional microbes	40
Long-offset paired nicking-based efficient and precise strategy for in vivo targeted insertion	40
Modeling the Human Body on Microfluidic Chips	40
Bioengineering human placentas: social implications of an advancing field	40
Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials	40
HHV-6 and HHV-7 reactivation in allogeneic CAR-T cell therapy	39
Marine-derived bioactive materials as antibiofilm and antivirulence agents	39
Bioprocessing technology of muscle stem cells: implications for cultured meat	38
Gallium-Based Liquid Metal Particles for Therapeutics	38
Apart, Together: Reflections on the COVID-19 Pandemic	36
Advisory Board and Contents	36
CRISPR-Cas12c: a noncleaving DNA binder with minimal PAM requirement	36
An epigenetic regulator synergizes with alphavirus-mediated gene therapy via biomimetic delivery for enhanced cancer therapy	36
Transforming undergraduate laboratory courses with interlinked real-world challenges	35
Biotechnology applications of proteins functionalized with DNA oligonucleotides	35
Distillation for in situ recovery of volatile fermentation products	35
Engineering Minds? Ethical Considerations on Biotechnological Approaches to Mental Health, Well-Being, and Human Flourishing	35
Harnessing synthetic biology to develop novel psychedelic therapies	34
SWATH-MS-Based Proteomics: Strategies and Applications in Plants	34
Overcoming Challenges in Expressing Iron–Sulfur Enzymes in Yeast	34
Light-induced programmable solid–liquid phase transition of biomolecular condensates for improved biosynthesis	34
Exploring standards for multicellular mammalian synthetic biology	33
Novel delivery systems for controlled release of bacterial therapeutics	32
pHNRhCas9NG, single expression cassette-based dual-component dual-transcription unit CRISPR/Cas9 system for plant genome editing	32
Product-driven high-throughput screening of industrial filamentous actinomycetes	32
Enzyme Catalyst Engineering toward the Integration of Biocatalysis and Chemocatalysis	32
RNA and nanocarriers: next generation drug and delivery platform take center stage	31
In Situ 3D Printing: Opportunities with Silk Inks	31
From Innovation to Application: Bridging the Valley of Death in Industrial Biotechnology	31
Emerging Applications of 3D Printing in Biomanufacturing	30
Chips, guts, and gas: unraveling volatile microbial mysteries in real time!	30
OMEGA-guided DNA polymerases enable random mutagenesis in a tunable window	30
Prime editor integrase systems boost targeted DNA insertion and beyond	30
Harnessing the microbial world for human benefit	30
Immunostimulation in experimental gas plasma therapy for breast cancer	30
Functionalization of Cellular Membranes with DNA Nanotechnology	29
Synthetic transcription factor engineering for cell and gene therapy	29
Dynamic anaerobic digestion-based biorefineries for on-demand renewable energy and bioproducts in a circular bioeconomy	29
Phase-separated biomolecular condensates for biocatalysis	29
Advancing plant gene activation with CRISPR-Act3.0	29
Oxygen-Releasing Biomaterials: Current Challenges and Future Applications	29
Systematic development of a highly efficient cell factory for 5-aminolevulinic acid production	29
Evading and overcoming AAV neutralization in gene therapy	29
Advisory Board and Contents	29
Large language model for knowledge synthesis and AI-enhanced biomanufacturing	28
Editing a healthier future in plants	28
Subscription and Copyright information	28
Subscription and Copyright information	28
The lignocellulosic biorefinery concept is sound: a commentary on Zhao et al.	27
Framing synthetic biology as an innovation-driven market	27
Advancements and regulations of biomanufacturing cell-based cartilage repair therapies	27
Nondestructive testing of native and tissue-engineered medical products: adding numbers to pictures	27
Blockchain as a frontier in biotechnology and bioenergy applications	27
Yeast-based screening platforms to understand and improve human health	26
Advancing wheat breeding using rye: a key contribution to wheat breeding history	26
Artificial intelligence in biomaterials: a call for unified biocompatibility standards	26
Sensors in blockchain	26
Intervertebral disc-on-a-chip: a precision engineered toolbox for low back pain studies	26
Bringing carbon to life via one-carbon metabolism	26
Programmable embedded bioprinting for one-step manufacturing of arterial models with customized contractile and metabolic functions	26
Chimeric antigen receptor therapy meets mRNA technology	25
The biotechnology revolution in textile dyeing	25
Prokaryotic Argonautes for in vivo biotechnology and molecular diagnostics	25
Shaping the future US bioeconomy through safety, security, sustainability, and social responsibility	25
Hydrogen production in microbial electrolysis cells with biocathodes	25
Robustness: linking strain design to viable bioprocesses	25
Power-to-vitamins: producing folate (vitamin B9) from renewable electric power and CO2 with a microbial protein system	25
Comparison of CRISPR/Cas and Argonaute for nucleic acid tests	25
Subscription and Copyright information	24

Subscription and Copyright information	24
Advisory Board and Contents	24
The File Drawer Problem in Nanomedicine	24
From 3D Back to 2D Monolayer Stomach Organoids-on-a-Chip	23
Media representations of synthetic biology in China	23
Synthetic biology for Taxol biosynthesis and sustainable production	23
Understanding and Assisting Reproduction in Wildlife Species Using Microfluidics	23
Cellular reprogramming and the rise of rejuvenation biotech	22
Learning from Nature to Expand the Genetic Code	22
Osmotic-controlled release oral tablets: technology and functional insights	22
Chairside live biotherapeutic hydrogel for comprehensive periodontitis therapy	22
Towards machine learning for hydrogel drug delivery systems	22
One-pot diagnostic methods based on CRISPR/Cas and Argonaute nucleases: strategies and perspectives	22
Extracellular Vesicles in Cardiac Regeneration: Potential Applications for Tissues-on-a-Chip	22
Insights on cisgenic plants with durable disease resistance under the European Green Deal	22
Driving towards digital biomanufacturing by CHO genome-scale models	21
Point-of-care detection devices for wound care and monitoring	21
Subscription and Copyright information	21
Subscription and Copyright information	21
EccDNA in plant-stress and biotechnological solutions in agriculture	20
Agricultural biotechnology for sustainable food security	20
Spatial -omics technologies: the new enterprise in 3D breast cancer models	20
Robotic micromotors transforming oral drug administration	20
Gene drive in species complexes: defining target organisms	20
A forward-thinking biocompatibility assessment: drafting future considerations now	20
TRYing to evaluate production costs in microbial biotechnology	20
Advances in ultrahigh-throughput screening technologies for protein evolution	20
Design of biomass-based renewable materials for environmental remediation	20
Validation Is Not Verification: Precise Terminology and Scientific Methods in Bioprocess Modeling	19
Untethered: using remote magnetic fields for regenerative medicine	19
Innovation trends in industrial biotechnology	19
Additive Manufacturing Tools to Improve the Performance of Chromatographic Approaches	19
Engineering next-generation oxygen-generating scaffolds to enhance bone regeneration	19
Harnessing microbes to pioneer environmental biophotoelectrochemistry	19
Protein–nucleic acid thermodynamic databases for specific uses	19
CarveAdornCurate: a versatile cloud-based platform for constructing multiscale metabolic models	19
A pathway to improve seaweed aquaculture through microbiota manipulation	19
A ventilated perfused lung model platform to dissect the response of the lungs to viral infection	18
Enhancing Biopolymer Hydrogel Functionality through Interpenetrating Networks	18
Biosensors for healthcare: current and future perspectives	18
Subscription and Copyright information	18
Quality by Design for enabling RNA platform production processes	18
Organs-on-chips: a decade of innovation	18
Efficiency and process development for microbial biomass production using oxic bioelectrosynthesis	18
CRISPR-based systems for sensitive and rapid on-site COVID-19 diagnostics	17
Microscopy imaging of living cells in metabolic engineering	17
Tapping the potential of Gram-positive bacteria for bioelectrochemical applications	17
Molecular farming for the food sector	17
Ethics and engagement: steering China’s synbio future	17
Engineering bacteria for production of sustainable polycyclopropanated jet fuel alternatives	17
Advisory Board and Contents	17
Creating novel metabolic pathways by protein engineering for bioproduction	17
Personalized, connected health enabled by AI and home-based diagnostics	17
Subscription and Copyright information	17
Subscription and Copyright information	17
In vitro human cell-based models: What can they do and what are their limitations?	17
Comment on ‘Thermodynamic database supports deciphering protein–nucleic acid interactions’	17
Extended reality gives digital agricultural biotechnology a new dimension	16
Safety evaluation of transgenic and genome-edited food animals	16
Subscription and Copyright information	16
Using Co-Culture to Functionalize Clostridium Fermentation	16
Are integrated bioelectrochemical technologies feasible for wastewater management?	16
Advisory Board and Contents	16
The spatial position effect: synthetic biology enters the era of 3D genomics	16
The winding journey of biotech capital raising: deciphering the jargon	16
Intellectual property and funding: fueling Chinese synbio	16
Improving plant C-to-G base editors with a cold-adapted glycosylase and TadA-8e variants	16
Synthetic Biology towards Engineering Microbial Lignin Biotransformation	16
Food allergen sensitization on a chip: the gut–immune–skin axis	16
Advisory Board and Contents	16
Advisory Board and Contents	16
Understanding phycosomal dynamics to improve industrial microalgae cultivation	16
Subscription and Copyright information	16
Thermodynamic database supports deciphering protein–nucleic acid interactions	16
Metabolic engineering for sustainability and health	16
Advisory Board and Contents	16
Tuning chitosan’s chemical structure for enhanced biological functions	15
Guidelines for selection and application of kinetics models in bioproduction processes	15
Tailor-made molecular imprints for biological event intervention	15
α-Synuclein seed amplification technology for Parkinson’s disease and related synucleinopathies	15
Making human eggs in a dish: are we close?	15
Manufacturing the multiscale vascular hierarchy: progress toward solving the grand challenge of tissue engineering	15
Modified nucleic acid aptamers: development, characterization, and biological applications	15
Bioengineering lipid-based synthetic cells for therapeutic protein delivery	15
Synovial joint-on-a-chip for modeling arthritis: progress, pitfalls, and potential	15
Cas9-PE: a robust multiplex gene editing tool for simultaneous precise editing and site-specific random mutation in rice	15
Exploiting unconventional prokaryotic hosts for industrial biotechnology	15
Precise engineering of the biomolecular corona to accelerate the clinical translation of lipid nanoparticles	14
Advisory Board and Contents	14
Biomimetic strategies and technologies for artificial tactile sensory systems	14
The Sustainable Path to a Circular Bioeconomy	14
Designing RNA switches for synthetic biology using inverse-RNA-folding	14
Brain organoids: building higher-order complexity and neural circuitry models	14
Progress and challenges in mass spectrometry-based analysis of antibody repertoires	14
An interactive metabolic map of bio-based chemicals	14