Trends in Biotechnology

Article	Citations
Subscription and Copyright information	284
Advisory Board and Contents	279
Vector-free intra-airway in vivo epigenetic editing	167
Bridging the path to multiplexed molecular diagnostics	163
Unlocking the potential of stem-cell-derived ‘synthetic’ embryo models	142
Vibrio natriegens as a host for rapid biotechnology	140
Electronic plants: the future of agriculture and urban ecosystems?	140
SynMADE: synthetic microbiota across diverse ecosystems	133
Auricular repair: symphony between scaffolds and stem cells	130
Manipulating immune activity of macrophages: a materials and mechanics perspective	116
(R)evolution-on-a-chip	108
The green revolution of food waste upcycling to produce polyhydroxyalkanoates	104
Analyzing and understanding the robustness of bioprocesses	102
Engineering biology approaches to modulate bacterial biofilms	99
Microalgae: a revolution for salt-affected soil remediation	97
Scalable tissue biofabrication via perfusable hollow fiber arrays for cultured meat applications	96
Phytohormones: novel strategy for removing emerging contaminants and recovering resources	96
Prime editing: advances and therapeutic applications	89
Healing wounds with plasma-activated hydrogel therapy	88
Smart materials: rational design in biosystems via artificial intelligence	85
Enzyme discovery and engineering for sustainable plastic recycling	82
Advisory Board and Contents	82
Subscription and Copyright information	81
Subscription and Copyright information	80
UFSC Biotech Network: a transdisciplinary platform for biotechnology innovation in Brazil	76

Subscription and Copyright information	76
The GPS for drug development: navigating with evidence from human populations	75
Advisory Board and Contents	74
Nanobotic microbiomes against emerging vascular pathogens in agriculture	72
Manufacturing innovation to drive down cell therapy costs	72
Ocular RNA nanomedicine: engineered delivery nanoplatforms in treating eye diseases	71
Towards biomanufacturing of cultured meat	70
Beyond waste: understanding urine’s potential in precision medicine	70
Extended human lymph node explants for evaluation of adaptive immunity	68
A high-performance protein preparation approach in a single column-free step	68
Molecular design of microalgae as sustainable cell factories	67
Integrating bicarbonate-based microalgal production with alkaline sewage for ocean negative carbon emissions	66
Engineering the mangrove soil microbiome for selection of polyethylene terephthalate-transforming bacterial consortia	65
Can protein expression be ‘solved’?	65
Machine learning to predict de novo protein–protein interactions	65
Multiscale models quantifying yeast physiology: towards a whole-cell model	64
Efficient genome-editing tools to engineer the recalcitrant non-model industrial microorganism Zymomonas mobilis	64
Printhead on a chip: empowering droplet-based bioprinting with microfluidics	63
Next-generation digital biomarkers: continuous molecular health monitoring using wearable devices	63
Mini-bones: miniaturized bone in vitro models	62
Machine learning in bioprocess development: from promise to practice	62
Translational organoid technology – the convergence of chemical, mechanical, and computational biology	62
Advisory Board and Contents	61
Emerging strategies to develop novel genetically encoded biosensors	61
Subscription and Copyright information	59
Next-generation 3D-printed nutritious food derived from waste plastic and biomass	59
Improving awareness, understanding, and enforcement of responsibilities and regulations in Blue Biotechnology	58
The LEGO® brick road to open science and biotechnology	57
Sebum analysis as an advantageous source of biomolecular information	56
3D extrusion bioprinting: rational bioink design and advanced fabrication techniques	56
Advisory Board and Contents	55
Dynamically regulating metabolic fluxes with synthetic metabolons	55
Metabolic and immunomodulatory control of type 2 diabetes via generating cellular itaconate reservoirs by inflammatory-targeting gene-therapy nanovesicles	54
Advisory Board and Contents	54
Advisory Board and Contents	52
Ethical challenges with 3D bioprinted tissues and organs	52
Frog ‘N’ Roll: novel synthetic peptides selective against Gram-negative pathogens	52
The morally disruptive future of reprogenetic enhancement technologies	52
Dynamic plasmid copy number control for synthetic biology	52
A new chapter for anti-idiotypes in low molecular weight compound immunoassays	50
Estimating environmental impacts of early-stage bioprocesses	50
Building biomaterials through genetic code expansion	49
Emerging supramolecular and living materials in oral medicine	49
Using synthetic biology to express nitrogenase biosynthesis pathway in rice and to overcome barriers of nitrogenase instability in plant cytosol	49
Engineered bacterial therapeutics with material solutions	49
Biosafety and biosecurity: treading China’s synbio tightrope	47
Synthetic biology for plant genetic engineering and molecular farming	47
Advances in lung biomimetic systems: exploring biophysical cues in lung regenerative medicine	46
Harnessing Streptomyces–plant interactions for agricultural natural product discovery	46
Small but mighty: emerging roles of uORFs in plants	46

Bioprinted, spatially defined breast tumor microenvironment models of intratumoral heterogeneity and drug resistance	46
Multienzymatic synthesis of nylon monomers from vegetable oils	46
Spatial omics for accelerating plant research and crop improvement	45
Trends in sustainable single-cell protein from non-grain feedstocks	45
3D printing of heart valves	45
Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy	45
Protein–glycan engineering in vaccine design: merging immune mechanisms with biotechnological innovation	44
Rethinking techno-moral disruption in bioethics, society, and justice	43
From academia to real-life biotech: ‘It takes a village’	43
Bringing the next biotechnologies to life	43
Rapid selection of transgenic mammalian cells via diphtheria toxin resistance	42
Academic entrepreneurship: promise and perils	42
Design principles for engineering light-controlled antibodies	42
Non-sterile cultivation of oleaginous organisms	42
Harnessing lactic acid bacteria in synthetic microbial consortia	42
Solar-driven PHB synthesis from wastewater by engineered semiconductor–bacteria biohybrids	41
Microbial electrosynthesis: opportunities for microbial pure cultures	40
Advances in induced anhydrobiosis for cell and gamete storage	40
Biotechnological approaches for producing natural pigments in yeasts	39
Molecular engineering of insulin for recombinant expression in yeast	39
One-pot production of colored bacterial cellulose	39
Next-generation industrial biotechnology for low-cost mass production of PHA	39
Bioengineering human placentas: social implications of an advancing field	38
Advanced strategies for enzyme–electrode interfacing in bioelectrocatalytic systems	38
Advisory Board and Contents	37
Long-offset paired nicking-based efficient and precise strategy for in vivo targeted insertion	37
Robots with a human touch	37
Subscription and Copyright information	37
Nanobodies: a new frontier in plant disease management	37
Making cow-free caseins and casein micelles	37
Advisory Board and Contents	36
Bioprocessing technology of muscle stem cells: implications for cultured meat	36
How transdisciplinarity can help biotech-driven biodiversity research	36
Computationally guided genome rewiring of Escherichia coli and its application for nanopolyethylene terephthalate (PET) biodegradation and upcycling	36
Engineering large-scale hiPSC-derived vessel-integrated muscle-like lattices for enhanced volumetric muscle regeneration	36
Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials	35
Marine-derived bioactive materials as antibiofilm and antivirulence agents	35
CRISPR screen-based mammalian cell engineering for complex biotherapeutics	35
HHV-6 and HHV-7 reactivation in allogeneic CAR-T cell therapy	35
Harnessing synthetic biology to develop novel psychedelic therapies	34
Efficient and sustained photosynthetic hydrogen production by algae under high light intensity	34
Merging automation and fundamental discovery into the design–build–test–learn cycle of nontraditional microbes	34
Exploring standards for multicellular mammalian synthetic biology	34
Transforming undergraduate laboratory courses with interlinked real-world challenges	33
Virus-like particles as modular interfaces for biomaterial functionalization	33
CRISPR-Cas12c: a noncleaving DNA binder with minimal PAM requirement	32
Clinical technology advances driving in vivo CAR therapy	32
Welfare impacts of China's regulatory change toward genome-edited crops	32
Novel delivery systems for controlled release of bacterial therapeutics	32
Engineering M13 phages: surface and morphological strategies for programmable applications	32
CRISPR/Cas-based personal glucose meters for nucleic acid detection	31
An epigenetic regulator synergizes with alphavirus-mediated gene therapy via biomimetic delivery for enhanced cancer therapy	31
pHNRhCas9NG, single expression cassette-based dual-component dual-transcription unit CRISPR/Cas9 system for plant genome editing	31
Biotechnology applications of proteins functionalized with DNA oligonucleotides	31
Organ-on-a-chip systems for modeling tumor and normal tissue microenvironments in radiotherapy research	30
Product-driven high-throughput screening of industrial filamentous actinomycetes	30
Engineered RNA nanostructures for scalable and efficient RNAi-based pesticides	30
Distillation for in situ recovery of volatile fermentation products	30
Light-induced programmable solid–liquid phase transition of biomolecular condensates for improved biosynthesis	29
Semi-automated biofoundry workflows for sequence coevolution-guided isoprene synthase engineering	29
Advancing plant gene activation with CRISPR-Act3.0	29
Rewiring holobiont systems with synthetic biology	28
Gas plasma technology mediates deep tissue and anticancer events independently of hydrogen peroxide	28
Systematic development of a highly efficient cell factory for 5-aminolevulinic acid production	28
OMEGA-guided DNA polymerases enable random mutagenesis in a tunable window	27
Prime editor integrase systems boost targeted DNA insertion and beyond	27
Harnessing piezoelectricity for musculoskeletal regeneration: microcurrents to tissue repair	27
Immunostimulation in experimental gas plasma therapy for breast cancer	27
Evading and overcoming AAV neutralization in gene therapy	27
RNA and nanocarriers: next generation drug and delivery platform take center stage	27
Synthetic transcription factor engineering for cell and gene therapy	27
Application of bacterial extracellular vesicles in gastrointestinal diseases	27
Staying productive under pressure: systems evaluations of β-carotene production in Yarrowia lipolytica under continuous fermentation	27
Ethical and legal considerations of digital animal models: pioneering reduction and replacement	26
Phase-separated biomolecular condensates for biocatalysis	26
Editing a healthier future in plants	26
Yeast-based screening platforms to understand and improve human health	26
Intervertebral disc-on-a-chip: a precision engineered toolbox for low back pain studies	26
Harnessing the microbial world for human benefit	26
Rational bioengineering of polysaccharide in designing of microbiome modulation	26

Sensors in blockchain	26
Subscription and Copyright information	26
Advisory Board and Contents	26
Chips, guts, and gas: unraveling volatile microbial mysteries in real time!	26
Dynamic anaerobic digestion-based biorefineries for on-demand renewable energy and bioproducts in a circular bioeconomy	26
Subscription and Copyright information	26
Advancements and regulations of biomanufacturing cell-based cartilage repair therapies	26
The lignocellulosic biorefinery concept is sound: a commentary on Zhao et al.	26
The biotechnology revolution in textile dyeing	25
Programmable embedded bioprinting for one-step manufacturing of arterial models with customized contractile and metabolic functions	25
Bringing carbon to life via one-carbon metabolism	25
Next-generation electroactive biomaterials-integrated bioelectronics for advanced healthcare management	25
Bioinspired thermoreversible bioink orchestrates focal adhesion-dependent osteogenesis	25
Human bone marrow organoids: emerging progress but persisting challenges	25
Shaping the future US bioeconomy through safety, security, sustainability, and social responsibility	25
Escherichia coli selection strains for growth-coupled metabolic engineering	24
Framing synthetic biology as an innovation-driven market	24
Hydrogen production in microbial electrolysis cells with biocathodes	24
Blockchain as a frontier in biotechnology and bioenergy applications	23
Large language model for knowledge synthesis and AI-enhanced biomanufacturing	23
Power-to-vitamins: producing folate (vitamin B9) from renewable electric power and CO2 with a microbial protein system	23
Robustness: linking strain design to viable bioprocesses	23
Comparison of CRISPR/Cas and Argonaute for nucleic acid tests	23
Advancing wheat breeding using rye: a key contribution to wheat breeding history	23
Artificial intelligence in biomaterials: a call for unified biocompatibility standards	23
Nondestructive testing of native and tissue-engineered medical products: adding numbers to pictures	23
Prokaryotic Argonautes for in vivo biotechnology and molecular diagnostics	23
Subscription and Copyright information	22
Cellular reprogramming and the rise of rejuvenation biotech	22
Engineering chimeric signaling proteins for microbial whole-cell biosensors: from design to deployment	22
Chimeric antigen receptor therapy meets mRNA technology	22
Strengthening the competitiveness of EU in vitro biotechnologies	22
Navigating microalgae under dynamic CO2 for waste-to-energy conversion	22
Pollutant degradation in saline wastewater using synthetic biology	21
Osmotic-controlled release oral tablets: technology and functional insights	21
Subscription and Copyright information	21
Chairside live biotherapeutic hydrogel for comprehensive periodontitis therapy	21
Media representations of synthetic biology in China	21
Insights on cisgenic plants with durable disease resistance under the European Green Deal	21
Reimagining colour with synthetic biology	21
New technologies for production of recombinant spider silk	21
Synthetic biology for Taxol biosynthesis and sustainable production	20
Large-scale manufacturing of human gallbladder epithelial cell products and derived hepatocytes via a chemically defined approach	20
EccDNA in plant-stress and biotechnological solutions in agriculture	20
Towards machine learning for hydrogel drug delivery systems	20
Subscription and Copyright information	20
Subscription and Copyright information	20
One-pot diagnostic methods based on CRISPR/Cas and Argonaute nucleases: strategies and perspectives	20
A forward-thinking biocompatibility assessment: drafting future considerations now	20
Point-of-care detection devices for wound care and monitoring	20
Gene drive in species complexes: defining target organisms	19
Robotic micromotors transforming oral drug administration	19
A ventilated perfused lung model platform to dissect the response of the lungs to viral infection	19
Protein–nucleic acid thermodynamic databases for specific uses	19
Microbial cellulose production using ocean water: sustainable and cost-effective?	19
Agricultural biotechnology for sustainable food security	19
Spatial -omics technologies: the new enterprise in 3D breast cancer models	19
Efficiency and process development for microbial biomass production using oxic bioelectrosynthesis	19
CarveAdornCurate: a versatile cloud-based platform for constructing multiscale metabolic models	19
Designing at-source and end-of-pipe biotechnologies to tackle pharmaceutical pollution	19
Design of biomass-based renewable materials for environmental remediation	18
Quality by Design for enabling RNA platform production processes	18
Harnessing microbes to pioneer environmental biophotoelectrochemistry	18
A pathway to improve seaweed aquaculture through microbiota manipulation	18
Innovation trends in industrial biotechnology	18
Holistic ecosystem strategies for boosting biopharma start-up success	18
Advances in ultrahigh-throughput screening technologies for protein evolution	18
TRYing to evaluate production costs in microbial biotechnology	18
Engineering next-generation oxygen-generating scaffolds to enhance bone regeneration	18
Ethics and engagement: steering China’s synbio future	18
Biosensors for healthcare: current and future perspectives	18
Driving towards digital biomanufacturing by CHO genome-scale models	18
Organs-on-chips: a decade of innovation	18
Untethered: using remote magnetic fields for regenerative medicine	18
Advisory Board and Contents	18
In vitro human cell-based models: What can they do and what are their limitations?	17
Personalized, connected health enabled by AI and home-based diagnostics	17
Challenges in realizing therapeutic antibody biosensing	17
Subscription and Copyright information	17
Engineering bacteria for production of sustainable polycyclopropanated jet fuel alternatives	17
Thermodynamic database supports deciphering protein–nucleic acid interactions	16
Tapping the potential of Gram-positive bacteria for bioelectrochemical applications	16
Microscopy imaging of living cells in metabolic engineering	16
Comment on ‘Thermodynamic database supports deciphering protein–nucleic acid interactions’	16
Molecular farming for the food sector	16
Creating novel metabolic pathways by protein engineering for bioproduction	15
The winding journey of biotech capital raising: deciphering the jargon	15
Meta-adaptive biomaterials: multiscale, spatiotemporal organization and actuation in engineered tissues	15
Are integrated bioelectrochemical technologies feasible for wastewater management?	15
Subscription and Copyright information	15
Metabolic engineering for sustainability and health	15
Gene therapy strategies in tissue engineering: advances and applications for regenerative therapy	15
CRISPR-based systems for sensitive and rapid on-site COVID-19 diagnostics	15
Advisory Board and Contents	15
Advances in biomimetic carbonic anhydrase strategies for CO2 capture	15