OOIR: Observatory of International Research

Papers

(The TQCC of Cancer and Metastasis Reviews is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Gastric cancer: a comprehensive review of current and future treatment strategies	299
The role of fibroblast activation protein in health and malignancy	175
Expression and function of epithelial cell adhesion molecule EpCAM: where are we after 40 years?	156
Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?	156
Molecular epidemiology and diagnostics of KRAS mutations in human cancer	147
FOXO transcription factor family in cancer and metastasis	139
CDK7 inhibitors as anticancer drugs	99
Lung cancer identification: a review on detection and classification	97
Molecular and cellular mechanisms underlying brain metastasis of breast cancer	77
Regulation of breast cancer metastasis signaling by miRNAs	74
Inhibitors of immune checkpoints—PD-1, PD-L1, CTLA-4—new opportunities for cancer patients and a new challenge for internists and general practitioners	72
Glioma: molecular signature and crossroads with tumor microenvironment	65
Current therapy of KRAS-mutant lung cancer	62
Checkpoint inhibitor therapy for metastatic triple-negative breast cancer	57
Wnts and the hallmarks of cancer	57
Prognostic and therapeutic role of tumor-infiltrating lymphocyte subtypes in breast cancer	56
Secreted frizzled-related protein 2: a key player in noncanonical Wnt signaling and tumor angiogenesis	51
Emerging links between endosomal pH and cancer	49
Collagen biology making inroads into prognosis and treatment of cancer progression and metastasis	48
The emerging role of Wnt5a in the promotion of a pro-inflammatory and immunosuppressive tumor microenvironment	48
Caveolin-1 function at the plasma membrane and in intracellular compartments in cancer	46
Neuroblastoma and the epigenome	46
The adipocyte microenvironment and cancer	43
Targeting KRAS in pancreatic cancer: new drugs on the horizon	41
Interaction between adipose tissue and cancer cells: role for cancer progression	41

Lipid metabolism reprogramming in renal cell carcinoma	38
The obesity-breast cancer link: a multidisciplinary perspective	37
The comprehensive landscape of miR-34a in cancer research	37
Gastrointestinal stromal tumor: a review of current and emerging therapies	36
Clinical utility of circulating tumor DNA as a response and follow-up marker in cancer therapy	34
The role of lipid species in membranes and cancer-related changes	33
Targeting the cytoskeleton against metastatic dissemination	33
An overview of genetic mutations and epigenetic signatures in the course of pancreatic cancer progression	32
The effects of mutant Ras proteins on the cell signalome	31
The plasticity of pancreatic cancer stem cells: implications in therapeutic resistance	31
Rethinking the biology of metastatic melanoma: a holistic approach	30
Tyrosine phosphorylation of tumor cell caveolin-1: impact on cancer progression	30
Neutrophil-derived granule cargoes: paving the way for tumor growth and progression	30
Long non-coding RNA: A recently accentuated molecule in chemoresistance in cancer	29
Role of non-coding RNAs in tumor progression and metastasis in pancreatic cancer	29
Flotillin membrane domains in cancer	29
The tumor microenvironment in pancreatic ductal adenocarcinoma: current perspectives and future directions	29
Glycosylation and raft endocytosis in cancer	29
Molecular mediators of peritoneal metastasis in pancreatic cancer	28
Caveolin-1, a master regulator of cellular senescence	28
Solute transporters and malignancy: establishing the role of uptake transporters in breast cancer and breast cancer metastasis	28
The role of microbiome in pancreatic cancer	27
K-Ras prenylation as a potential anticancer target	25
The role of caspase-8 in the tumor microenvironment of ovarian cancer	25
Epigenetic dynamics in cancer stem cell dormancy	24
Unraveling mucin domains in cancer and metastasis: when protectors become predators	24
MDA-9/Syntenin/SDCBP: new insights into a unique multifunctional scaffold protein	24
Anti-HER2 therapy in metastatic breast cancer: many choices and future directions	23
The race to develop oral SERDs and other novel estrogen receptor inhibitors: recent clinical trial results and impact on treatment options	23
Inflammatory bowel disease and carcinogenesis	23
Chemokines orchestrate tumor cells and the microenvironment to achieve metastatic heterogeneity	23
Platelets as messengers of early-stage cancer	22
Centrosome amplification: a quantifiable cancer cell trait with prognostic value in solid malignancies	22
Cyclin-dependent kinase inhibitors in head and neck cancer and glioblastoma—backbone or add-on in immune-oncology?	22
Role of myeloid-derived suppressor cells in metastasis	21
The role of the metabolite cargo of extracellular vesicles in tumor progression	21
Obesity: a perfect storm for carcinogenesis	21
Role of linoleic acid-derived oxylipins in cancer	20
Metformin: review of epidemiology and mechanisms of action in pancreatic cancer	20
Current methods in translational cancer research	19
Dormancy, stemness, and therapy resistance: interconnected players in cancer evolution	19
Current therapy of advanced colorectal cancer according to RAS/RAF mutational status	19
Exosomes: a new perspective in EGFR-mutated lung cancer	19
Platelets in aging and cancer—“double-edged sword”	19
Treatment against glucose-dependent cancers through metabolic PFKFB3 targeting of glycolytic flux	19
Targeting DNA damage repair pathways in pancreas cancer	18
Epigenetic modulation of immunotherapy and implications in head and neck cancer	18
Extracellular citrate and metabolic adaptations of cancer cells	18
Safety of radiosurgery concurrent with systemic therapy (chemotherapy, targeted therapy, and/or immunotherapy) in brain metastases: a systematic review	18
Mechanistic insights into the interplays between neutrophils and other immune cells in cancer development and progression	18

Membrane tension buffering by caveolae: a role in cancer?	18
Multiple roles of HOX proteins in Metastasis: Let me count the ways	18