Biochimica et Biophysica Acta-Molecular Cell Research

Article	Citations
Glycogen synthase kinase-3 signaling in Alzheimer's disease	226
Copper metabolism as a unique vulnerability in cancer	182
Targeting apoptotic caspases in cancer	180
Molecular mechanisms of stress granule assembly and disassembly	177
Role of S100 proteins in health and disease	163
GSK-3β in DNA repair, apoptosis, and resistance of chemotherapy, radiotherapy of cancer	118
Mechanistic concepts of iron-sulfur protein biogenesis in Biology	111
Getting out what you put in: Copper in mitochondria and its impacts on human disease	103
Autophagy and the Wnt signaling pathway: A focus on Wnt/β-catenin signaling	94
m6A-YTHDF1-mediated TRIM29 upregulation facilitates the stem cell-like phenotype of cisplatin-resistant ovarian cancer cells	74
NCOA4-mediated ferritinophagy promotes ferroptosis induced by erastin, but not by RSL3 in HeLa cells	69
Fungal iron homeostasis with a focus on Aspergillus fumigatus	66
Negri bodies and other virus membrane-less replication compartments	59
The requirement for cobalt in vitamin B12: A paradigm for protein metalation	57
Liquid-liquid phase separation as a common organizing principle of intracellular space and biomembranes providing dynamic adaptive responses	54
MicroRNAs as major regulators of the autophagy pathway	53
Combating deleterious phase transitions in neurodegenerative disease	52
Maintaining social contacts: The physiological relevance of organelle interactions	52
Deregulated PTEN/PI3K/AKT/mTOR signaling in prostate cancer: Still a potential druggable target?	51
Pyrenoids: CO2-fixing phase separated liquid organelles	50
Management versus miscues in the cytosolic labile iron pool: The varied functions of iron chaperones	49
Organellar calcium signaling in plants: An update	46
One ring to bring them all and in the darkness bind them: The trafficking of heme without deliverers	46
Long non-coding RNAs and transposable elements: A functional relationship	45
Cathepsin B is an executioner of ferroptosis	43

Interactions between reactive oxygen species and autophagy	42
Molybdenum cofactor biology, evolution and deficiency	42
β1-Integrin binding to collagen type 1 transmits breast cancer cells into chemoresistance by activating ABC efflux transporters	41
Nicotinamide N-methyltransferase in endothelium protects against oxidant stress-induced endothelial injury	41
Heme biosynthesis in prokaryotes	40
Epithelial-to-mesenchymal transition as the driver of changing carcinoma and glioblastoma microenvironment	40
It's time to die: BH3 mimetics in solid tumors	39
The balancing act of NEET proteins: Iron, ROS, calcium and metabolism	38
A comprehensive overview of the complex world of the endo- and sarcoplasmic reticulum Ca2+-leak channels	38
CISD2 maintains cellular homeostasis	38
Tools and techniques for illuminating the cell biology of zinc	38
Fe-S cluster biogenesis by the bacterial Suf pathway	37
Role of damage and management in muscle hypertrophy: Different behaviors of muscle stem cells in regeneration and hypertrophy	37
Pro-apoptotic complexes of BAX and BAK on the outer mitochondrial membrane	36
Aminoacyl-tRNA synthetases and amino acid signaling	36
From economy to luxury: Copper homeostasis in Chlamydomonas and other algae	36
Crosstalks of GSK3 signaling with the mTOR network and effects on targeted therapy of cancer	35
Analysis of biomolecular condensates and protein phase separation with microfluidic technology	33
Impact of intercellular crosstalk between epidermal keratinocytes and dermal fibroblasts on skin homeostasis	33
Iron and manganese transport in mammalian systems	31
The role of Bcl-2 proteins in modulating neuronal Ca2+ signaling in health and in Alzheimer's disease	31
Iron-sulfur cluster biogenesis, trafficking, and signaling: Roles for CGFS glutaredoxins and BolA proteins	30
The role of Smad2 and Smad3 in regulating homeostatic functions of fibroblasts in vitro and in adult mice	30
Brain-derived neurotrophic factor (BDNF) promotes molecular polarization and differentiation of immature neuroblastoma cells into definitive neurons	29
The diversity of ACBD proteins – From lipid binding to protein modulators and organelle tethers	29
Cell death as a result of calcium signaling modulation: A cancer-centric prospective	28
Phase separation of FG-nucleoporins in nuclear pore complexes	26
Death sentence: The tale of a fallen endoplasmic reticulum	26
The role of lysosomal cathepsins in neurodegeneration: Mechanistic insights, diagnostic potential and therapeutic approaches	25
Function and proteolytic generation of the soluble interleukin-6 receptor in health and disease	25
The biochemistry of lanthanide acquisition, trafficking, and utilization	24
Adaptation to iron deficiency in human pathogenic fungi	24
Role of calpains in promoting desmin filaments depolymerization and muscle atrophy	24
Mitochondrial fission factor (MFF) is a critical regulator of peroxisome maturation	23
Signalling by extracellular nucleotides in health and disease	23
Interdependent allosteric free fatty acid receptor 2 modulators synergistically induce functional selective activation and desensitization in neutrophils	23
Platelet-derived extracellular vesicles regulate cell cycle progression and cell migration in breast cancer cells	23
The role of GSK3 in metabolic pathway perturbations in cancer	22
Heat shock increases levels of reactive oxygen species, autophagy and apoptosis	22
Nuclear accumulation of pyruvate dehydrogenase alpha 1 promotes histone acetylation and is essential for zygotic genome activation in porcine embryos	22
Cancer cell death strategies by targeting Bcl-2's BH4 domain	21
Cepharanthine, a novel selective ANO1 inhibitor with potential for lung adenocarcinoma therapy	21
Melanopsin mediates UVA-dependent modulation of proliferation, pigmentation, apoptosis, and molecular clock in normal and malignant melanocytes	21
Regulation of gene expression via translational buffering	21
IL-8 secreted by tumor associated macrophages contribute to lapatinib resistance in HER2-positive locally advanced breast cancer via activation of Src/STAT3/ERK1/2-mediated EGFR signaling	20
Pathways of heme utilization in fungi	20
Anti-cancer actions of carnosine and the restoration of normal cellular homeostasis	20
SP/NK1R system regulates carcinogenesis in prostate cancer: Shedding light on the antitumoral function of aprepitant	20
Heat shock proteins in cell signaling and cancer	20
ISG15 suppresses translation of ABCC2 via ISGylation of hnRNPA2B1 and enhances drug sensitivity in cisplatin resistant ovarian cancer cells	20

Leading the invasion: The role of Cathepsin S in the tumour microenvironment	20
Initiation of stress granule assembly by rapid clustering of IGF2BP proteins upon osmotic shock	20
SK2 channel regulation of neuronal excitability, synaptic transmission, and brain rhythmic activity in health and diseases	19
An update on factor XII-driven vascular inflammation	19
Apparent stiffness of vimentin intermediate filaments in living cells and its relation with other cytoskeletal polymers	19
PAK2 activated by Cdc42 and caspase 3 mediates different cellular responses to oxidative stress-induced apoptosis	19
MiR-7 mediates mitochondrial impairment to trigger apoptosis and necroptosis in Rhabdomyosarcoma	19
Control of neuronal excitability by GSK-3beta: Epilepsy and beyond	19
Two-pore and TRP cation channels in endolysosomal osmo-/mechanosensation and volume regulation	19
IKKβ activation promotes amphisome formation and extracellular vesicle secretion in tumor cells	19
Peripheral IL-6/STAT3 signaling promotes beiging of white fat	19
Keeping zombies alive: The ER-mitochondria Ca2+ transfer in cellular senescence	18
Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD	18
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway	17
Study of ER stress and apoptotic proteins in the heart and tumor exposed to doxorubicin	17
The functional cross talk between cancer cells and cancer associated fibroblasts from a cancer mechanics perspective	17
FGFR1 overexpression renders breast cancer cells resistant to metformin through activation of IRS1/ERK signaling	17
The cross-talk of NOTCH and GSK-3 signaling in colon and other cancers	17
Heterogeneity of chemical composition of lipid droplets in endothelial inflammation and apoptosis	17
Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis	16
DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication	16
Unraveling the multifaceted nature of the nuclear function of mTOR	16
Oxidative stress induces transcription of telomeric repeat-containing RNA (TERRA) by engaging PKA signaling and cytoskeleton dynamics	16
Interferon-γ and high glucose-induced opening of Cx43 hemichannels causes endothelial cell dysfunction and damage	16
Direct and indirect effects of tubulin post-translational modifications on microtubule stability: Insights and regulations	16
Calcium dynamically alters erythrocyte mechanical response to shear	16
Molecular mechanism of intermediate filament recognition by plakin proteins	16
ADAR1 Transcriptome editing promotes breast cancer progression through the regulation of cell cycle and DNA damage response	16
Cooperative roles of PAK1 and filamin A in regulation of vimentin assembly and cell extension formation	16
Ubiquitin-dependent proteasomal degradation of AMPK gamma subunit by Cereblon inhibits AMPK activity	15
Shear stress stimulates integrin β1 trafficking and increases directional migration of cancer cells via promoting deacetylation of microtubules	15
Irreversible alterations in the hemoglobin structure affect oxygen binding in human packed red blood cells	15
Connecting the “dots”: RNP granule network in health and disease	15
Regulation of Hippo signaling by metabolic pathways in cancer	15
Roles for Ca2+ and K+ channels in cancer cells exposed to the hypoxic tumour microenvironment	15
MARK2/4 promotes Warburg effect and cell growth in non-small cell lung carcinoma through the AMPKα1/mTOR/HIF-1α signaling pathway	15
Mitochondrial calcium drives clock gene-dependent activation of pyruvate dehydrogenase and of oxidative phosphorylation	15
A cellular atlas of calcineurin signaling	14
“Janus” efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms	14
Altered mitochondrial fusion drives defensive glutathione synthesis in cells able to switch to glycolytic ATP production	14
The fate of damaged mitochondrial DNA in the cell	14
Live-cell ATR-FTIR spectroscopy as a novel bioanalytical tool for cell glucose metabolism research	14
VGLL1 phosphorylation and activation promotes gastric cancer malignancy via TGF-β/ERK/RSK2 signaling	14
GSK3 and miRNA in neural tissue: From brain development to neurodegenerative diseases	14
Par-4 regulates autophagic cell death in human cancer cells via upregulating p53 and BNIP3	14
Alterations and molecular targeting of the GSK-3 regulator, PI3K, in head and neck cancer	14
Transcriptomic and epigenomic landscapes of Alzheimer's disease evidence mitochondrial-related pathways	14
Sphingosine-1-phosphate induces migration of microglial cells via activation of volume-sensitive anion channels, ATP secretion and activation of purinergic receptors	14
NMK-BH2, a novel microtubule-depolymerising bis (indolyl)-hydrazide-hydrazone, induces apoptotic and autophagic cell death in cervical cancer cells by binding to tubulin at colchicine – site	14
TRPC6 channel and its implications in breast cancer: an overview	14
Plasma membrane wound repair is characterized by extensive membrane lipid and protein rearrangements in vascular endothelial cells	14
Molecular insights into peroxisome homeostasis and peroxisome biogenesis disorders	14
Distinctive role of SIK1 and SIK3 isoforms in aerobic glycolysis and cell growth of breast cancer through the regulation of p53 and mTOR signaling pathways	13
Combined role for YAP-TEAD and YAP-RUNX2 signalling in substrate-stiffness regulation of cardiac fibroblast proliferation	13
Wnt/β-catenin signaling and p68 conjointly regulate CHIP in colorectal carcinoma	13
Atorvastatin prevents hearing impairment in the presence of hyperlipidemia	13
Assembly of bacterial cell division protein FtsZ into dynamic biomolecular condensates	13
UBXN7 cofactor of CRL3KEAP1 and CRL2VHL ubiquitin ligase complexes mediates reciprocal regulation of NRF2 and HIF-1α proteins	13
Deciphering a distinct regulatory network of TEAD4, CDX2 and GATA3 in humans for trophoblast transition from embryonic stem cells	13
A novel role of HSP90 in regulating osteoclastogenesis by abrogating Rab11b-driven transport	13
Overexpression of budding yeast protein phosphatase Ppz1 impairs translation	13
Cathepsin C is a novel mediator of podocyte and renal injury induced by hyperglycemia	13
ADAM17 orchestrates Interleukin-6, TNFα and EGF-R signaling in inflammation and cancer	13
CXXC5 orchestrates Stat3/Erk/Akt signaling networks to modulate P. gingivalis-elicited autophagy in cementoblasts	13
Site-1 and site-2 proteases: A team of two in regulated proteolysis	13
The role of rhomboid superfamily members in protein homeostasis: Mechanistic insight and physiological implications	13
Resistance to CDK4/6 inhibition: Mechanisms and strategies to overcome a therapeutic problem in the treatment of hormone receptor-positive metastatic breast cancer	13
The Swedish dilemma - the almost exclusive use of APPswe-based mouse models impedes adequate evaluation of alternative β-secretases	13
Characterization of mitochondrial calpain-5	13
Neuropeptide bombesin receptor activation stimulates growth of lung cancer cells through HER3 with a MAPK-dependent mechanism	13
The interaction between nucleophosmin/NPM1 and the large ribosomal subunit precursors contribute to maintaining the nucleolar structure	13
Role of the HIF oxygen sensing pathway in cell defense and proliferation through the control of amino acid metabolism	13
BAG5 promotes invasion of papillary thyroid cancer cells via upregulation of fibronectin 1 at the translational level	13
Cellular iron sensing and regulation: Nuclear IRP1 extends a classic paradigm	13
Differential regulation of the glucocorticoid receptor nucleocytoplasmic shuttling by TPR-domain proteins	13
Control of cell metabolism by the epidermal growth factor receptor	13
PAR2 blockade reverses osimertinib resistance in non-small-cell lung cancer cells via attenuating ERK-mediated EMT and PD-L1 expression	12
Lysophosphatidic acid receptor 5 transactivation of TGFBR1 stimulates the mRNA expression of proteoglycan synthesizing genes XYLT1 and CHST3	12
Significance of nuclear cathepsin V in normal thyroid epithelial and carcinoma cells	12
Visfatin regulates Pg LPS-induced proinflammatory/prodegradative effects in healthy and inflammatory periodontal cells partially via NF-κB pathway	12

The high expression of MTH1 and NUDT5 promotes tumor metastasis and indicates a poor prognosis in patients with non-small-cell lung cancer	12
JAK2 regulates Nav1.6 channel function via FGF14Y158 phosphorylation	12
Hypomorphic CAMKK2 in EA.hy926 endothelial cells causes abnormal transferrin trafficking, iron homeostasis and glucose metabolism	12
Roles of Id1/HIF-1 and CDK5/HIF-1 in cell cycle reentry induced by amyloid-beta peptide in post-mitotic cortical neuron	12
Transient receptor potential channel regulation by growth factors	12
GLP-1 regulates exercise endurance and skeletal muscle remodeling via GLP-1R/AMPK pathway	12
In situ AFM detection of the stiffness of the in situ exposed cell nucleus	12
Glycogen synthase kinase-3 signaling in cellular and behavioral responses to psychostimulant drugs	12
The IP3 receptor and Ca2+ signaling in trypanosomes	12
Artemisinin and its derivatives target mitochondrial c-type cytochromes in yeast and human cells	12
DTX3L induced NLRP3 ubiquitination inhibit R28 cell pyroptosis in OGD/R injury	12
BNIP3 and Nix: Atypical regulators of cell fate	12
Regulation of SIRT2 by Wnt/β-catenin signaling pathway in colorectal cancer cells	12
Src couples estrogen receptor to the anticipatory unfolded protein response and regulates cancer cell fate under stress	12
GSK-3: An important kinase in colon and pancreatic cancers	12
Extracellular AGR2 triggers lung tumour cell proliferation through repression of p21CIP1	11
TMEM70 forms oligomeric scaffolds within mitochondrial cristae promoting in situ assembly of mammalian ATP synthase proton channel	11
MRP5 nitration by NO-releasing gemcitabine encapsulated in liposomes confers sensitivity in chemoresistant pancreatic adenocarcinoma cells	11
The perinuclear region concentrates disordered proteins with predicted phase separation distributed in a 3D network of cytoskeletal filaments and organelles	11
Long non-coding antisense RNA HYOU1-AS is essential to human breast cancer development through competitive binding hnRNPA1 to promote HYOU1 expression	11
Role of CNC1 gene in TDP-43 aggregation-induced oxidative stress-mediated cell death in S. cerevisiae model of ALS	11
Cardiac regeneration as an environmental adaptation	11
Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-β1	11
Expression of nuclear XIAP associates with cell growth and drug resistance and confers poor prognosis in breast cancer	11
P5B-ATPases in the mammalian polyamine transport system and their role in disease	11
Amlexanox exerts anti-inflammatory actions by targeting phosphodiesterase 4B in lipopolysaccharide-activated macrophages	11
Menadione-induced endothelial inflammation detected by Raman spectroscopy	11
Hypoxia induced ALKBH5 prevents spontaneous abortion by mediating m6A-demethylation of SMAD1/5 mRNAs	11
The role of proteolysis in interleukin-11 signaling	11
AMOTL2 inhibits JUN Thr239 dephosphorylation by binding PPP2R2A to suppress the proliferation in non-small cell lung cancer cells	11
The calcium pump PMCA4 prevents epithelial-mesenchymal transition by inhibiting NFATc1-ZEB1 pathway in gastric cancer	11
Claudin-2 binding peptides, VPDSM and DSMKF, down-regulate claudin-2 expression and anticancer resistance in human lung adenocarcinoma A549 cells	11
Human amylin aggregates release within exosomes as a protective mechanism in pancreatic β cells: Pancreatic β-hippocampal cell communication	11
There and back again: Intracellular trafficking, release and recycling of matrix metalloproteinases	10
Glycogen synthase kinase (GSK)-3 and the double-strand RNA-dependent kinase, PKR: When two kinases for the common good turn bad	10
Zinc homeostasis and signaling in the roundworm C. elegans	10
Elabela/toddler: New peptide with a promising future in cancer diagnostic and therapy	10
Control of cell signaling by Arf GTPases and their regulators: Focus on links to cancer and other GTPase families	10
The prion protein and its ligands: Insights into structure-function relationships	10
ORAI3 silencing alters cell proliferation and promotes mitotic catastrophe and apoptosis in pancreatic adenocarcinoma	10
GSK-3-associated signaling is crucial to virus infection of cells	10
TFB2M and POLRMT are essential for mammalian mitochondrial DNA replication	10
Metabotropic signaling cascade involved in α4β2 nicotinic acetylcholine receptor-mediated PKCβII activation	10
LGALS1 acts as a pro-survival molecule in AML	10
The promyelocytic leukemia protein isoform PML1 is an oncoprotein and a direct target of the antioxidant sulforaphane (SFN)	10
Effects of pharmacological calcimimetics on colorectal cancer cells over-expressing the human calcium-sensing receptor	10
Choreographing endo-lysosomal Ca2+ throughout the life of a phagosome	10
GSK-3 in liver diseases: Friend or foe?	10