Antiviral Research

Article	Citations
Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern	333
The omicron (B.1.1.529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters	94
A cell-based assay to discover inhibitors of SARS-CoV-2 RNA dependent RNA polymerase	70
Antiviral activity and safety of remdesivir against SARS-CoV-2 infection in human pluripotent stem cell-derived cardiomyocytes	65
Global update on the susceptibilities of human influenza viruses to neuraminidase inhibitors and the cap-dependent endonuclease inhibitor baloxavir, 2018–2020	64
An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral	52
Combination therapy with nirmatrelvir and molnupiravir improves the survival of SARS-CoV-2 infected mice	52
Benefit-risk assessment for brincidofovir for the treatment of smallpox: U.S. Food and Drug Administration's Evaluation	51
Emerging antiviral therapeutics for human adenovirus infection: Recent developments and novel strategies	50
Emetine suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E	50
A robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents	50
Very low levels of remdesivir resistance in SARS-COV-2 genomes after 18 months of massive usage during the COVID19 pandemic: A GISAID exploratory analysis	48
Discovery of chebulagic acid and punicalagin as novel allosteric inhibitors of SARS-CoV-2 3CLpro	46
Characterization of the antiviral effects of REP 2139 on the HBV lifecycle in vitro	45
Burden of influenza B virus infection and considerations for clinical management	44
Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development	39
Proteomic analysis identifies the RNA helicase DDX3X as a host target against SARS-CoV-2 infection	37
Preclinical evaluation of Imatinib does not support its use as an antiviral drug against SARS-CoV-2	36
Betulinic acid exhibits antiviral effects against dengue virus infection	35
A bacterial artificial chromosome (BAC)-vectored noninfectious replicon of SARS-CoV-2	35
Inhibition of coronavirus infection by a synthetic STING agonist in primary human airway system	35
Genetic conservation of SARS-CoV-2 RNA replication complex in globally circulating isolates and recently emerged variants from humans and minks suggests minimal pre-existing resistance to remdesivir	34
Selinexor, a novel selective inhibitor of nuclear export, reduces SARS-CoV-2 infection and protects the respiratory system in vivo	34
A circular mRNA vaccine prototype producing VFLIP-X spike confers a broad neutralization of SARS-CoV-2 variants by mouse sera	33
Cinnamic acid inhibits Zika virus by inhibiting RdRp activity	33

HBV evolution and genetic variability: Impact on prevention, treatment and development of antivirals	30
A synthetic STING agonist inhibits the replication of human parainfluenza virus 3 and rhinovirus 16 through distinct mechanisms	30
The rocaglate CR-31-B (−) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo	29
Allosteric inhibitors of the main protease of SARS-CoV-2	29
Diketo acids inhibit the cap-snatching endonuclease of several Bunyavirales	29
Inhibition of herpes simplex virus 1 by cepharanthine via promoting cellular autophagy through up-regulation of STING/TBK1/P62 pathway	29
Cathelicidin antimicrobial peptides suppress EV71 infection via regulating antiviral response and inhibiting viral binding	28
Combined in silico and in vitro approaches identified the antipsychotic drug lurasidone and the antiviral drug elbasvir as SARS-CoV2 and HCoV-OC43 inhibitors	28
Influenza antivirals and their role in pandemic preparedness	28
E3 ubiquitin ligase TRIM21 restricts hepatitis B virus replication by targeting HBx for proteasomal degradation	28
Hepatoprotective, antioxidant, anti-inflammatory, and antiviral activities of silymarin against mayaro virus infection	27
Broad spectrum anti-coronavirus activity of a series of anti-malaria quinoline analogues	27
Influenza polymerase inhibitor resistance: Assessment of the current state of the art - A report of the isirv Antiviral group	27
Clinical outcome and the role of antivirals in congenital cytomegalovirus infection	27
Effectiveness of pegylated interferon monotherapy in the treatment of chronic hepatitis D virus infection: A meta-analysis	25
Punicalagin as an allosteric NSP13 helicase inhibitor potently suppresses SARS-CoV-2 replication in vitro	25
Virucidal and antiviral activity of astodrimer sodium against SARS-CoV-2 in vitro	25
Effective deploying of a novel DHODH inhibitor against herpes simplex type 1 and type 2 replication	25
Drug screening identified gemcitabine inhibiting hepatitis E virus by inducing interferon-like response via activation of STAT1 phosphorylation	25
Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening	25
Targeting host DEAD-box RNA helicase DDX3X for treating viral infections	23
Iminosugars: A host-targeted approach to combat Flaviviridae infections	23
Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for antiviral strategies	23
Antiviral activities of four marine sulfated glycans against adenovirus and human cytomegalovirus	23
S-adenosylmethionine-dependent methyltransferase inhibitor DZNep blocks transcription and translation of SARS-CoV-2 genome with a low tendency to select for drug-resistant viral variants	22
Inhibition of p38 signaling curtails the SARS-CoV-2 induced inflammatory response but retains the IFN-dependent antiviral defense of the lung epithelial barrier	22
Antiviral drugs targeting endosomal membrane proteins inhibit distant animal and human pathogenic viruses	22
Perspectives on stopping nucleos(t)ide analogues therapy in patients with chronic hepatitis B	22
Identification of Niemann-Pick C1 protein as a potential novel SARS-CoV-2 intracellular target	22
5-Iodotubercidin inhibits SARS-CoV-2 RNA synthesis	20
Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase	20
Kill or corrupt: Mechanisms of action and drug-resistance of nucleotide analogues against SARS-CoV-2	20
Immunobiology of Crimean-Congo hemorrhagic fever	20
Current status of silica-based nanoparticles as therapeutics and its potential as therapies against viruses	20
New methylene blue derivatives suggest novel anti-orthopoxviral strategies	19
Clinical and virological responses to a broad-spectrum human monoclonal antibody in an influenza virus challenge study	19
COVID-19, Influenza and RSV: Surveillance-informed prevention and treatment – Meeting report from an isirv-WHO virtual conference	19
A human recombinant analogue to plasma-derived vaccinia immunoglobulin prophylactically and therapeutically protects against lethal orthopoxvirus challenge	19
Different efficacies of neutralizing antibodies and antiviral drugs on SARS-CoV-2 Omicron subvariants, BA.1 and BA.2	19
In vitro and in vivo evaluation of the main protease inhibitor FB2001 against SARS-CoV-2	19
Artificial intelligence: Machine learning approach for screening large database and drug discovery	18
Establishment of a stable SARS-CoV-2 replicon system for application in high-throughput screening	18
Susceptibility of widely diverse influenza a viruses to PB2 polymerase inhibitor pimodivir	18
Intramolecular recombination enables the formation of hepatitis B virus (HBV) cccDNA in mice after HBV genome transfer using recombinant AAV vectors	18
Conserved coronavirus proteins as targets of broad-spectrum antivirals	18
The novel therapeutic target and inhibitory effects of PF-429242 against Zika virus infection	17
Reverse genetic systems of SARS-CoV-2 for antiviral research	17
Next-generation sequencing for cytomegalovirus antiviral resistance genotyping in a clinical virology laboratory	17
Substitution-inert polynuclear platinum compounds inhibit human cytomegalovirus attachment and entry	16
Picomolar inhibition of SARS-CoV-2 variants of concern by an engineered ACE2-IgG4-Fc fusion protein	16

NK-lysin peptides ameliorate viral encephalopathy and retinopathy disease signs and provide partial protection against nodavirus infection in European sea bass	16
Phenothiazines inhibit SARS-CoV-2 cell entry via a blockade of spike protein binding to neuropilin-1	16
Identification of potential inhibitors of protein-protein interaction useful to fight against Ebola and other highly pathogenic viruses	16
ACE2-Fc fusion protein overcomes viral escape by potently neutralizing SARS-CoV-2 variants of concern	15
Duration of fever and symptoms in children after treatment with baloxavir marboxil and oseltamivir during the 2018–2019 season and detection of variant influenza a viruses with polymerase acidic subun	15
Suppression effect of plant-derived berberine on cyprinid herpesvirus 2 proliferation and its pharmacokinetics in Crucian carp (Carassius auratus gibelio)	15
A mouse model of lethal respiratory dysfunction for SARS-CoV-2 infection	15
Potential application of antiviral coumarin in aquaculture against IHNV infection by reducing viral adhesion to the epithelial cell surface	15
Targeting the NS2B-NS3 protease of tick-borne encephalitis virus with pan-flaviviral protease inhibitors	15
Evaluation of antiviral drugs against newly emerged SARS-CoV-2 Omicron subvariants	15
Generation of a reporter yellow fever virus for high throughput antiviral assays	15
Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro	15
Isocotoin suppresses hepatitis E virus replication through inhibition of heat shock protein 90	15
Baloxavir-oseltamivir combination therapy inhibits the emergence of resistant substitutions in influenza A virus PA gene in a mouse model	15
Unraveling the antiviral activity of plitidepsin against SARS-CoV-2 by subcellular and morphological analysis	15
Hepatitis D virus: Improving virological knowledge to develop new treatments	14
Immunodetection assays for the quantification of seasonal common cold coronaviruses OC43, NL63, or 229E infection confirm nirmatrelvir as broad coronavirus inhibitor	14
Preclinical characterization of AB-506, an inhibitor of HBV replication targeting the viral core protein	14
TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity	14
Nirmatrelvir exerts distinct antiviral potency against different human coronaviruses	14
Helicase primase inhibitors (HPIs) are efficacious for therapy of human herpes simplex virus (HSV) disease in an infection mouse model	14
A dengue type 2 reporter virus assay amenable to high-throughput screening	14
JNJ-64794964 (AL-034/TQ-A3334), a TLR7 agonist, induces sustained anti-HBV activity in AAV/HBV mice via non-cytolytic mechanisms	13
GS-441524 inhibits African swine fever virus infection in vitro	13
Generation of a VeroE6 Pgp gene knock out cell line and its use in SARS-CoV-2 antiviral study	13
Co-delivery of Cas9 mRNA and guide RNAs edits hepatitis B virus episomal and integration DNA in mouse and tree shrew models	13
Discovery of novel SARS-CoV-2 inhibitors targeting the main protease Mpro by virtual screenings and hit optimization	13
Antiviral susceptibility of clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses isolated from birds and mammals in the United States, 2022	13
A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency	13
Nucleolin mediates SARS-CoV-2 replication and viral-induced apoptosis of host cells	12
Geneticin shows selective antiviral activity against SARS-CoV-2 by interfering with programmed −1 ribosomal frameshifting	12
Chromatin-mediated epigenetic regulation of HSV-1 transcription as a potential target in antiviral therapy	12
Ergosterol peroxide inhibits HBV infection by inhibiting the binding of the pre-S1 domain of LHBsAg to NTCP	12
Reversible covalent inhibitors suppress enterovirus 71 infection by targeting the 3C protease	12
In vitro and in vivo efficacy of a novel nucleoside analog H44 against Crimean–Congo hemorrhagic fever virus	12
Identification of hepatitis B virus core protein residues critical for capsid assembly, pgRNA encapsidation and resistance to capsid assembly modulators	12
Therapeutics for flaviviral infections	12
The NF-κB inhibitor, SC75741, is a novel antiviral against emerging tick-borne bandaviruses	12
Remdesivir inhibits the polymerases of the novel filoviruses Lloviu and Bombali virus	12
Development and characterization of recombinant tick-borne encephalitis virus expressing mCherry reporter protein: A new tool for high-throughput screening of antiviral compounds, and neutralizing ant	12
A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors	12
Nafamostat mesylate as a broad-spectrum candidate for the treatment of flavivirus infections by targeting envelope proteins	12
Identification of a novel inhibitor targeting influenza A virus group 2 hemagglutinins	12
Ganciclovir and maribavir susceptibility phenotypes of cytomegalovirus UL97 ATP binding region mutations detected by expanded genotypic testing	12
Flavivirus NS4B protein: Structure, function, and antiviral discovery	12
Hydroxypropyl-beta-cyclodextrin (HP-BCD) inhibits SARS-CoV-2 replication and virus-induced inflammatory cytokines	12
The life cycle of the alphaviruses: From an antiviral perspective	12
Licochalcone A inhibits enterovirus A71 replication in vitro and in vivo	12
First clinical description of letermovir resistance mutation in cytomegalovirus UL51 gene and potential impact on the terminase complex structure	11
Viral replicon particles protect IFNAR−/− mice against lethal Crimean-Congo hemorrhagic fever virus challenge three days after vaccination	11
Loss of hepatitis D virus infectivity upon farnesyl transferase inhibitor treatment associates with increasing RNA editing rates revealed by a new RT-ddPCR method	11
Comparative analysis of the molecular mechanism of resistance to vapendavir across a panel of picornavirus species	11
Evaluation of molnupiravir (EIDD-2801) efficacy against SARS-CoV-2 in the rhesus macaque model	11
Dengue NS1 induces phospholipase A2 enzyme activity, prostaglandins, and inflammatory cytokines in monocytes	11
Hydroxychloroquine and azithromycin used alone or combined are not effective against SARS-CoV-2 ex vivo and in a hamster model	11
Infectious bronchitis virus: Identification of Gallus gallus APN high-affinity ligands with antiviral effects	11
Relative frequency of cytomegalovirus UL56 gene mutations detected in genotypic letermovir resistance testing	11
Cyclic lipopeptides as membrane fusion inhibitors against SARS-CoV-2: New tricks for old dogs	11
Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404	11
Niclosamide inhibits hepatitis E virus through suppression of NF-kappaB signalling	10
Mpox virus mRNA-lipid nanoparticle vaccine candidates evoke antibody responses and drive protection against the Vaccinia virus challenge in mice	10
Inhibiting cytomegalovirus replication through targeting the host electron transport chain	10
Endogenous cathelicidin is required for protection against ZIKV-caused testis damage via inactivating virons	10
New directions in the experimental therapy of tick-borne encephalitis	10
miRNAs derived from milk small extracellular vesicles inhibit porcine epidemic diarrhea virus infection	10
Synergistic in-vitro antiviral effects of combination treatment using anidulafungin and T-1105 against Zika virus infection	10
Broad spectrum compounds targeting early stages of rabies virus (RABV) infection	10
AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5	10
Adefovir dipivoxil efficiently inhibits the proliferation of pseudorabies virus in vitro and in vivo	10
SERS based rapid and ultrasensitive detection of Japanese Encephalitis Virus	10
Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production	10
In vitro and in vivo antiviral activity of nucleoside analogue cHPMPC against African swine fever virus replication	10
Vector-borne viruses in Turkey: A systematic review and bibliography	10
The calcium channel inhibitor lacidipine inhibits Zika virus replication in neural progenitor cells	10
Reliable quantification of Cytomegalovirus DNAemia in Letermovir treated patients	10
Repurposing of HIV/HCV protease inhibitors against SARS-CoV-2 3CLpro	10
Ponesimod suppresses hepatitis B virus infection by inhibiting endosome maturation	10
BIKE regulates dengue virus infection and is a cellular target for broad-spectrum antivirals	10
Potent inhibition of diverse Omicron sublineages by SARS-CoV-2 fusion-inhibitory lipopeptides	10
Metabolic regulation of the HBV-specific T cell function	10

Genotypic correlates of resistance to the HIV-1 strand transfer integrase inhibitor cabotegravir	10
Targeting SARS-CoV-2 and host cell receptor interactions	10
A novel cell culture model reveals the viral interference during hepatitis B and C virus coinfection	10
Activity of Sotrovimab against BQ.1.1 and XBB.1 Omicron sublineages in a hamster model	9
SARS-CoV-2 Permissive glioblastoma cell line for high throughput antiviral screening	9
Hemin protects against Zika virus infection by disrupting virus-endosome fusion	9
5-(Perylen-3-ylethynyl)uracil as an antiviral scaffold: Potent suppression of enveloped virus reproduction by 3-methyl derivatives in vitro	9
An antibody engineering platform using amino acid networks: A case study in development of antiviral therapeutics	9
Importin α/β-dependent nuclear transport of human parvovirus B19 nonstructural protein 1 is essential for viral replication	9
ML-SA1 and SN-2 inhibit endocytosed viruses through regulating TRPML channel expression and activity	9
2-((1H-indol-3-yl)thio)-N-phenyl-acetamides: SARS-CoV-2 RNA-dependent RNA polymerase inhibitors	9
A pan-serotype antiviral to prevent and treat dengue: A journey from discovery to clinical development driven by public-private partnerships	9
Novel siRNA therapeutics demonstrate multi-variant efficacy against SARS-CoV-2	9
Methodology-dependent performance of serum HBV RNA in predicting treatment outcomes in chronic hepatitis B patients	9
Identification of structurally re-engineered rocaglates as inhibitors against hepatitis E virus replication	9
Bergamottin, a bioactive component of bergamot, inhibits SARS-CoV-2 infection in golden Syrian hamsters	9
A fluorescence-based, gain-of-signal, live cell system to evaluate SARS-CoV-2 main protease inhibition	9
Pinostrobin from plants and propolis against human coronavirus HCoV-OC43 by modulating host AHR/CYP1A1 pathway and lipid metabolism	9
High dose sofosbuvir and sofosbuvir-plus-ribavirin therapy inhibit Hepatitis E Virus (HEV) replication in a rabbit model for acute HEV infection	9
Duration of fever and symptoms in influenza-infected children treated with baloxavir marboxil during the 2019–2020 season in Japan and detection of influenza virus with the PA E23K substitution	9
Increased ILT2 expression contributes to dysfunction of CD56dimCD16+NK cells in chronic hepatitis B virus infection	9
Lipid balance remodelling by human positive-strand RNA viruses and the contribution of lysosomes	8
Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19	8
Homoseongomycin, a compound isolated from marine actinomycete bacteria K3-1, is a potent inhibitor of encephalitic alphaviruses	8
Mechanism of interferon alpha therapy for chronic hepatitis B and potential approaches to improve its therapeutic efficacy	8
Anti-viral effect in chronic hepatitis B patients with normal or mildly elevated alanine aminotransferase	8
Novel quinolone derivatives targeting human dihydroorotate dehydrogenase suppress Ebola virus infection in vitro	8
Advancing Marburg virus antiviral screening: Optimization of a novel T7 polymerase-independent minigenome system	8
Importin KPNA2 confers HIV-1 pre-integration complex nuclear import by interacting with the capsid protein	8
Antiviral effects of deoxynojirimycin (DNJ)-based iminosugars in dengue virus-infected primary dendritic cells	8
Virological and clinical outcomes in outpatients treated with baloxavir or oseltamivir: A Japanese multicenter study in the 2019–2020 influenza season	8
The race toward a universal influenza vaccine: Front runners and the future directions	8
Prevalence of cytomegalovirus antiviral drug resistance in transplant recipients	8
Artesunate inhibits PDE4 leading to intracellular cAMP accumulation, reduced ERK/MAPK signaling, and blockade of influenza A virus vRNP nuclear export	8
Inhibition of endocytosis of porcine reproductive and respiratory syndrome virus by rottlerin and its potential prophylactic administration in piglets	8
Conserved use of the sodium/bile acid cotransporter (NTCP) as an entry receptor by hepatitis B virus and domestic cat hepadnavirus	8
Remodeling of immunological biomarkers in patients with chronic hepatitis C treated with direct-acting antiviral therapy	8
Novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2	8
Safety, pharmacokinetics and pharmacodynamics of SYN023 alone or in combination with a rabies vaccine: An open, parallel, single dose, phase 1 bridging study in healthy Chinese subjects	8
Wnt antagonists suppress herpes simplex virus type 1 productive infection	8
Lassa virus antigen distribution and inflammation in the ear of infected strain 13/N Guinea pigs	8
75 years of bovine viral diarrhea virus: Current status and future applications of the use of directed antivirals	8
Design and characterization of novel SARS-CoV-2 fusion inhibitors with N-terminally extended HR2 peptides	8
Unexpected complete recovery of a patient with severe tick-borne encephalitis treated with favipiravir	8
Identification of a novel acylthiourea-based potent broad-spectrum inhibitor for enterovirus 3D polymerase in vitro and in vivo	8
Avian anti-NS1 IgY antibodies neutralize dengue virus infection and protect against lethal dengue virus challenge	7
A novel model based on qAnti-HBc and conventional biomarkers for identifying significant liver injury among CHB patients with ALT ≤ ULN	7
Targeted protein degradation as an antiviral approach	7
Inhibition of a broad range of SARS-CoV-2 variants by antiviral phytochemicals in hACE2 mice	7
Cryptotanshinone protects porcine alveolar macrophages from infection with porcine reproductive and respiratory syndrome virus	7
Characterization of a thiourea derivative that targets viral transactivators of cytomegalovirus and herpes simplex virus type 1	7
27-Hydroxycholesterol inhibits rhinovirus replication in vitro and on human nasal and bronchial histocultures without selecting viral resistant variants	7
Development of cycling probe based real-time PCR methodology for influenza A viruses possessing the PA/I38T amino acid substitution associated with reduced baloxavir susceptibility	7
The prophylactic and therapeutic efficacy of the broadly active antiviral ribonucleoside N-Hydroxycytidine (EIDD-1931) in a mouse model of lethal Ebola virus infection	7
Inhibitory effect of a novel thiazolidinedione derivative on hepatitis B virus entry	7
Quindoline-derivatives display potent G-quadruplex-mediated antiviral activity against herpes simplex virus 1	7
A broad-spectrum nanobody targeting the C-terminus of the hepatitis B surface antigen for chronic hepatitis B infection therapy	7
RNA-Binding motif protein 38 (RBM38) mediates HBV pgRNA packaging into the nucleocapsid	7
In vitro and in vivo efficacy of Metformin against dengue	7
Efficacy and safety of antiviral treatments for symptomatic COVID-19 outpatients: Systematic review and network meta-analysis	7
Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39	7
Sulfated β-glucan from Agaricus subrufescens inhibits flavivirus infection and nonstructural protein 1-mediated pathogenesis	7
Screening of an epigenetic compound library identifies BRD4 as a potential antiviral target for hepatitis B virus covalently closed circular DNA transcription	7
Effects of targeting sumoylation processes during latent and induced Epstein-Barr virus infections using the small molecule inhibitor ML-792	7
Prophylactic treatment with BX795 blocks activation of AKT and its downstream targets to protect vaginal keratinocytes and vaginal epithelium from HSV-2 infection	7
Insights on the antiviral mechanisms of action of the TLR1/2 agonist Pam3CSK4 in hepatitis B virus (HBV)-infected hepatocytes	7
CDK4/6 inhibitor palbociclib promotes SARS-CoV-2 cell entry by down-regulating SKP2 dependent ACE2 degradation	7
Novel bispecific human antibody platform specifically targeting a fully open spike conformation potently neutralizes multiple SARS-CoV-2 variants	7
Animal models for studying coronavirus infections and developing antiviral agents and vaccines	7
Identification of antiviral compounds against equid herpesvirus-1 using real-time cell assay screening: Efficacy of decitabine and valganciclovir alone or in combination	7
Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics	7
Sulforaphane suppresses dengue virus replication by inhibition of dengue protease and enhancement of antiviral interferon response through Nrf2-mediated heme oxygenase-1 induction	7
Host RNA quality control as a hepatitis B antiviral target	7
Isolation of human monoclonal antibodies with neutralizing activity to a broad spectrum of SARS-CoV-2 viruses including the Omicron variants	6
A proof-of-concept study for the efficacy of dispirotripiperazine PDSTP in a rabbit model of herpes simplex epithelial keratitis	6
Development of MDCK-based quadrivalent split seasonal influenza virus vaccine with high safety and immunoprotection: A preclinical study	6
The antifungal drug isavuconazole inhibits the replication of human cytomegalovirus (HCMV) and acts synergistically with anti-HCMV drugs	6
Lipid phosphatase SAC1 suppresses hepatitis B virus replication through promoting autophagic degradation of virions	6
Identification of quinolone derivatives as effective anti-Dengue virus agents	6
Inhibitors of mpox VP39 2′-O methyltransferase efficiently inhibit the monkeypox virus	6
Rapid discovery and classification of inhibitors of coronavirus infection by pseudovirus screen and amplified luminescence proximity homogeneous assay	6
Characterization of an air-liquid interface primary human vaginal epithelium to study Ebola virus infection and testing of antivirals	6
Paxlovid for hospitalized COVID-19 patients with chronic kidney disease	6
Investigation of multidrug-resistance mutations of hepatitis B virus (HBV) in a large cohort of chronic HBV-infected patients with treatment of nucleoside/nucleotide analogs	6
Janus kinase-inhibition modulates hepatitis E virus infection	6
Polyphenylene carboxymethylene (PPCM) microbicide repurposed as antiviral against SARS-CoV-2. Proof of concept in primary human undifferentiated epithelial cells	6
Implications of the antiviral drug favipiravir on rabies immunoglobulin for post-exposure prophylaxis of rabies in mice model with category III-like exposures	6
RBM24 inhibits the translation of SARS-CoV-2 polyproteins by targeting the 5ʹ-untranslated region	6
Liver biopsy of chronic hepatitis B patients indicates HBV integration profile may complicate the endpoint and effect of entecavir treatment	6
Comparison of the effects of different potent adjuvants on enhancing the immunogenicity and cross-protection by influenza virus vaccination in young and aged mice	6
Baseline serum hepatitis B core antibody level predicts HBeAg seroconversion in patients with HBeAg-positive chronic hepatitis B after antiviral treatment	6
Establishment of a robust rat hepatitis E virus fecal-oral infection model and validation for antiviral studies	6
AMG487 inhibits PRRSV replication and ameliorates lung injury in pig lung xenografts by down-regulating the expression of ANXA2	6
Porcine β-defensin 2 confers enhanced resistance to swine flu infection in transgenic pigs and alleviates swine influenza virus-induced apoptosis possibly through interacting with host SLC25A4	6
Posaconazole inhibits multiple steps of the alphavirus replication cycle	6