Trends in Neurosciences

Article	Citations
The Emerging Science of Interoception: Sensing, Integrating, Interpreting, and Regulating Signals within the Self	328
Neural Circuits of Interoception	192
Signaling by cGAS–STING in Neurodegeneration, Neuroinflammation, and Aging	155
Functions of Interoception: From Energy Regulation to Experience of the Self	153
Magnetoencephalography with optically pumped magnetometers (OPM-MEG): the next generation of functional neuroimaging	149
Prefrontal Cortex Development in Health and Disease: Lessons from Rodents and Humans	145
Blood–Brain Barrier Dynamics to Maintain Brain Homeostasis	145
Circuit organization of the rodent medial prefrontal cortex	144
Astrocytic processes: from tripartite synapses to the active milieu	144
Diseases, Disorders, and Comorbidities of Interoception	143
Mitochondria and Calcium in Alzheimer’s Disease: From Cell Signaling to Neuronal Cell Death	143
Cellular senescence at the crossroads of inflammation and Alzheimer's disease	137
A Unifying Account of Angular Gyrus Contributions to Episodic and Semantic Cognition	134
The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2	133
Immunometabolism in the Brain: How Metabolism Shapes Microglial Function	130
Microglial Phagocytosis: A Disease-Associated Process Emerging from Alzheimer’s Disease Genetics	125
Hippocampal contributions to social and cognitive deficits in autism spectrum disorder	122
Computational Models of Interoception and Body Regulation	117
Interventions and Manipulations of Interoception	114
How critical is brain criticality?	110
Spinal Muscular Atrophy: In the Challenge Lies a Solution	103
Is COVID-19 a Perfect Storm for Parkinson’s Disease?	102
Pupillometry as an integrated readout of distinct attentional networks	100
16p11.2 Copy Number Variations and Neurodevelopmental Disorders	88
Cause or consequence? Alpha oscillations in visuospatial attention	87

Lysosomal dysfunction in neurodegeneration: emerging concepts and methods	81
Non-cell-autonomous pathogenic mechanisms in amyotrophic lateral sclerosis	78
LRRK2 and idiopathic Parkinson’s disease	76
The many dimensions of human hippocampal organization and (dys)function	75
Modulating the Neuromodulators: Dopamine, Serotonin, and the Endocannabinoid System	75
Neurovascular coupling: motive unknown	73
Functional interplay between central and autonomic nervous systems in human fear conditioning	71
Entorhinal cortex dysfunction in Alzheimer's disease	71
Neurobiology of the lateral septum: regulation of social behavior	71
A Vessel for Change: Endothelial Dysfunction in Cerebral Small Vessel Disease	69
Transforming the Concept of Memory Reactivation	69
The Multifaceted Roles of KCC2 in Cortical Development	68
The quest for multiscale brain modeling	68
The use of language in autism research	67
A Dendrite-Focused Framework for Understanding the Actions of Ketamine and Psychedelics	67
Extracellular Vesicles as an Emerging Frontier in Spinal Cord Injury Pathobiology and Therapy	66
Microglia in Cancer Therapy-Related Cognitive Impairment	66
Basal Progenitor Morphology and Neocortex Evolution	65
How cancer hijacks the body’s homeostasis through the neuroendocrine system	65
Brain cell type-specific cholesterol metabolism and implications for learning and memory	62
Using artificial neural networks to ask ‘why’ questions of minds and brains	60
The paraventricular nucleus of the thalamus: an integrative node underlying homeostatic behavior	58
Astrocyte and neuron cooperation in long-term depression	57
Olfactory dysfunction in COVID-19: new insights into the underlying mechanisms	57
Mitochondria-lysosome contact site dynamics and misregulation in neurodegenerative diseases	56
α-Synuclein in synaptic function and dysfunction	56
50 years of mnemonic persistent activity: quo vadis?	54
Calcium-dependent docking of synaptic vesicles	53
Macrophages on the margin: choroid plexus immune responses	52
Dopamine ‘ups and downs’ in addiction revisited	52
The Tail of the Striatum: From Anatomy to Connectivity and Function	50
Where is the error? Hierarchical predictive coding through dendritic error computation	49
Interbrain synchrony: on wavy ground	47
Extracellular Vesicle-Mediated Bilateral Communication between Glioblastoma and Astrocytes	47
Mitochondrial signalling and homeostasis: from cell biology to neurological disease	46
Cortical disinhibitory circuits: cell types, connectivity and function	46
The foundation and architecture of precision medicine in neurology and psychiatry	45
Local cholesterol metabolism orchestrates remyelination	44
Why is everyone talking about brain state?	44
Connecting TDP-43 Pathology with Neuropathy	43
Distributional Reinforcement Learning in the Brain	43
Insulin action in the brain: cell types, circuits, and diseases	43
Going beyond primary motor cortex to improve brain–computer interfaces	43
Mitochondrial dysfunction as a trigger of programmed axon death	42
RNA N6-Methyladenosine and the Regulation of RNA Localization and Function in the Brain	42
Regulation of GABAARs by Transmembrane Accessory Proteins	42
Interferon γ: a master cytokine in microglia-mediated neural network dysfunction and neurodegeneration	41
Alcohol and the brain: from genes to circuits	40
Neural consequences of chronic sleep disruption	40
Polar angle asymmetries in visual perception and neural architecture	40

Walking with Salamanders: From Molecules to Biorobotics	39
Deep learning and the Global Workspace Theory	39
The emerging association between COVID-19 and acute stroke	39
Neural basis of prosocial behavior	39
Peripheral Innervation in the Regulation of Glucose Homeostasis	38
Beneficial and detrimental functions of microglia during viral encephalitis	38
Watch and Learn: The Cognitive Neuroscience of Learning from Others’ Actions	38
Proteostatic regulation in neuronal compartments	38
Translational approaches to understanding resilience to Alzheimer’s disease	38
Trace amine-associated receptor 1 (TAAR1) agonism as a new treatment strategy for schizophrenia and related disorders	37
To look or not to look: dissociating presaccadic and covert spatial attention	37
VPS10P Domain Receptors: Sorting Out Brain Health and Disease	37
Intercellular Communication in the Nervous System Goes Viral	37
Condensate biology of synaptic vesicle clusters	36
Surface-based hippocampal subfield segmentation	35
Mechanical Forces Orchestrate Brain Development	35
Regulation of circuit organization and function through inhibitory synaptic plasticity	34
Circuit-Based Biomarkers for Mood and Anxiety Disorders	34
Rethinking stress resilience	33
Moving beyond amyloid and tau to capture the biological heterogeneity of Alzheimer’s disease	32
Mechanistic flexibility of the retrosplenial cortex enables its contribution to spatial cognition	32
Excitotoxicity Revisited: Mitochondria on the Verge of a Nervous Breakdown	31
Drosophila Mechanosensory Transduction	31
The calcium-dependent protease calpain in neuronal remodeling and neurodegeneration	31
α7 nicotinic acetylcholine receptors in the hippocampal circuit: taming complexity	31
Deep entorhinal cortex: from circuit organization to spatial cognition and memory	30
A Network Perspective on Sensorimotor Learning	30
A predictive coding framework of allostatic–interoceptive overload in frontotemporal dementia	30
Mitochondria: new players in homeostatic regulation of firing rate set points	29
The iPSC perspective on schizophrenia	29
Oxidized phospholipids as novel mediators of neurodegeneration	29
Spinal ascending pathways for somatosensory information processing	29
Insights and opportunities for deep brain stimulation as a brain circuit intervention	28
Cognition through the lens of a body–brain dynamic system	28
Prefrontal cortex as a key node in arousal circuitry	28
Circadian clock, diurnal glucose metabolic rhythm, and dawn phenomenon	28
Unraveling the dynamics of dopamine release and its actions on target cells	28
Understanding Vulnerability and Adaptation in Early Brain Development using Network Neuroscience	27
How the immune system shapes neurodegenerative diseases	27
Neuroinflammation associated with ultrasound-mediated permeabilization of the blood–brain barrier	26
Informing deep neural networks by multiscale principles of neuromodulatory systems	25
Neurobiology of brain oscillations in acute and chronic pain	25
Disabled in academia: to be or not to be, that is the question	25
Foundations and implications of astrocyte heterogeneity during brain development and disease	25
Neurofeedback through the lens of reinforcement learning	24
Orexin (hypocretin) and addiction	24
Inflammasome assembly in neurodegenerative diseases	24
Bidirectional Brain-Systemic Interactions and Outcomes After TBI	24
How do protein aggregates escape quality control in neurodegeneration?	23
Persistent nociceptor hyperactivity as a painful evolutionary adaptation	23
Beyond sex differences: short- and long-term effects of pregnancy on the brain	23
How Bacteria Impact Host Nervous System and Behaviors: Lessons from Flies and Worms	23
Little cells of the little brain: microglia in cerebellar development and function	23
Construction of complex memories via parallel distributed cortical–subcortical iterative integration	23
Malnutrition and the microbiome as modifiers of early neurodevelopment	23
PTEN mutations in autism spectrum disorder and congenital hydrocephalus: developmental pleiotropy and therapeutic targets	23
The Raphe Dopamine System: Roles in Salience Encoding, Memory Expression, and Addiction	22
A Circuit-Based Information Approach to Substance Abuse Research	22
Neuroprotective versus Neuroinflammatory Roles of Complement: From Development to Disease	22
Spatiotemporally resolved protein synthesis as a molecular framework for memory consolidation	22
Reinforcement learning detuned in addiction: integrative and translational approaches	22
Dynamic coupling of oscillatory neural activity and its roles in visual attention	21
Learning offline: memory replay in biological and artificial reinforcement learning	20
Crossmodal plasticity in hearing loss	20
The dorsal raphe nucleus in the control of energy balance	20
Induced pluripotent stem cells: a tool for modeling Parkinson’s disease	20
PET Imaging as a Tool for Assessing COVID-19 Brain Changes	20
A call for more clarity around causality in neuroscience	19
Subtypes of Alzheimer’s disease: questions, controversy, and meaning	18
The feasibility of artificial consciousness through the lens of neuroscience	18
Control of energy homeostasis by the lateral hypothalamic area	17
TDP-43 Puts the STING in ALS	17
Contributions by metaplasticity to solving the Catastrophic Forgetting Problem	17
What can we learn from inactivation studies? Lessons from auditory cortex	17
MicroRNA regulation of critical retinal pigment epithelial functions	17
Microglial diversity in neuropathic pain	16
Cell type-specific dissection of sensory pathways involved in descending modulation	16
Pathological potential of oligodendrocyte precursor cells: terra incognita	16
Poststroke arm and hand paresis: should we target the cervical spinal cord?	16
A critical period plasticity framework for the sensorimotor–association axis of cortical neurodevelopment	16

The common marmoset as a model of neurodegeneration	15
Genetic insights into the neurobiology of anxiety	15
Neurovascular adaptations modulating cognition, mood, and stress responses	15
Continual task learning in natural and artificial agents	15
Control of lymph node activity by direct local innervation	15
Emerging approaches for decoding neuropeptide transmission	15
SARS-CoV-2-specific neuropathology: fact or fiction?	15
Transposable elements and Alzheimer’s disease pathogenesis	15
Synapse organizers as molecular codes for synaptic plasticity	15
The impact of stress on the hippocampal spatial code	15
Synergistic effects of brain injury and aging: common mechanisms of proteostatic dysfunction	14
Bridging the big (data) gap: levels of control in small- and large-scale cognitive neuroscience research	14
Retinal receptive-field substructure: scaffolding for coding and computation	14
Cancer as a homeostatic challenge: the role of the hypothalamus	14
Emerging roles of oligodendrocyte precursor cells in neural circuit development and remodeling	14
Excitatory GluN1/GluN3A glycine receptors (eGlyRs) in brain signaling	14
Evaluating microglial phenotypes using single-cell technologies	14
The neuroscience of music – towards ecological validity	14
The systemic immune response in Parkinson’s disease: focus on the peripheral immune component	14
Probing mechanisms of visual spatial attention in mice	13
Whole-head OPM-MEG enables noninvasive assessment of functional connectivity	13
IGF2 in memory, neurodevelopmental disorders, and neurodegenerative diseases	13
The structure of cyclic nucleotide-gated channels in rod and cone photoreceptors	13
How iron can drive neurodegeneration	13
Consider the pons: bridging the gap on sensory prediction abnormalities in schizophrenia	13
Mental navigation and the neural mechanisms of insight	12
Alternative Frameworks for Advancing the Study of Eating Disorders	12
Gamma oscillations and episodic memory	12
Probing top-down information in neocortical layer 1	12
Large-scale, closed-loop interrogation of neural circuits underlying cognition	12
Continuously changing memories: a framework for proactive and non-linear consolidation	12
Alterations in pain during adolescence and puberty	12
Toward a neurobiology of internal selective attention	12
Blood–brain crosstalk: the roles of neutrophils, platelets, and neutrophil extracellular traps in neuropathologies	11
Alzheimer’s disease and related tauopathies: disorders of disrupted neuronal identity	11
Neuronal and astrocyte determinants of critical periods of plasticity	11
‘Ups, downs, and sideways’ of dopamine in drug addiction	11
RNA granules in neuronal plasticity and disease	11
Prerequisites of language acquisition in the newborn brain	11
Somatosensory neuron types and their neural networks as revealed via single-cell transcriptomics	11
Understanding the aging hypothalamus, one cell at a time	11
The role of the hippocampus in the consolidation of emotional memories during sleep	11
Useful misrepresentation: perception as embodied proactive inference	10
Intercellular signaling by ectodomain shedding at the synapse	10
Autophagy Pathways in CNS Myeloid Cell Immune Functions	10
The locus coeruleus as a global model failure system	10
Distinct globus pallidus circuits regulate motor and cognitive functions	10
Microglia moonlighting after traumatic brain injury: aging and interferons influence chronic microglia reactivity	10
Air pollution, glymphatic impairment, and Alzheimer's disease	10
Birdsong neuroscience and the evolutionary substrates of learned vocalization	10
The tricky business of defining brain functions	10
Nonapoptotic caspases in neural development and in anesthesia-induced neurotoxicity	10
Internal models of self-motion: neural computations by the vestibular cerebellum	10
Tuning neural circuits and behaviors by microglia in the adult brain	10
Neonatal development of intestinal neuroimmune interactions	10
Epigenetic mechanisms underlying sex differences in the brain and behavior	10
White matter injury across neurodegenerative disease	9
Neuronal pericellular baskets: neurotransmitter convergence and regulation of network excitability	9
Nonsense-mediated mRNA decay in neuronal physiology and neurodegeneration	9
Astrocytes: integrators of arousal state and sensory context	9
Astrocytes in selective vulnerability to neurodegenerative disease	9
The 'middle-aging' brain	9
Links between the brain and body during sleep: implications for memory processing	9
High-resolution optogenetics in space and time	9
Reassessing neurodegenerative disease: immune protection pathways and antagonistic pleiotropy	9
Maladaptive explore/exploit trade-offs in schizophrenia	9
Social and vocal complexity in bottlenose dolphins	8
The endolysosomal pathway and ALS/FTD	8
T cells direct microglial repair of white matter after stroke	8
Toward identifying key mechanisms of progression in multiple sclerosis	8
Ocular and extraocular roles of neuropsin in vertebrates	8
Curiosity-driven exploration: foundations in neuroscience and computational modeling	8
Septo-hippocampal dynamics and the encoding of space and time	7
Toward individualized connectomes of brain morphology	7
Ctenophores and the evolutionary origin(s) of neurons	7
Reassessing synaptic adhesion pathways	7
'Scary' pericytes: the fibrotic scar in brain and spinal cord lesions	7
The neuropathogenesis of highly pathogenic avian influenza H5Nx viruses in mammalian species including humans	6
Addressing the Gender Gap in Research: Insights from a Women in Neuroscience Conference	6
Roles of visually evoked and spontaneous activity in the development of retinal direction selectivity maps	6
Multisensory navigation and neuronal plasticity in desert ants	6
Interplay between metabolic energy regulation and memory pathways in Drosophila	6
How REM sleep shapes hypothalamic computations for feeding behavior	6
Lysosomes in retinal health and disease	6
A misadventure of the correlation coefficient	6
The therapeutic potential of natural killer cells in neuropathic pain	6
Altered stress granule disassembly: links to neurodegenerative disease?	6
The potential of gene editing for Huntington’s disease	6
Convergent actions of stress and stimulants via epigenetic regulation of neural circuitry	6
Eye movements in Parkinson’s disease: from neurophysiological mechanisms to diagnostic tools	5
CB2 and toll-like receptors crosstalk in microglia	5
The microbiome–nose–brain axis in health and disease	5
Neuroscience of cognitive control in crows	5
Evolutionary neuroanatomical expansion of Broca’s region serving a human-specific function	5
Hidden variables in stress neurobiology research	5