TRAC-Trends in Analytical Chemistry

Article	Citations
Editorial Board	728
Editorial	485
Editorial Board	302
Applications of thread-based microfluidics: Approaches and options for detection	221
3D printed microfluidics for cell biological applications	186
Design strategies and applications of responsive metal-based luminescence probes in the bioanalysis	166
Unique role of molecular imaging probes for viral infection	152
On the road to automation: a comparative review on chemometric strategies for GC-MS data analysis	151
Single-molecule detection-based super-resolution imaging in single-cell analysis: Inspiring progress and future prospects	149
Multidimensional single-cell analysis: Diverse strategies and emerging applications in the life sciences	145
Hydroxyapatite-based composites as efficient sorbents: Fabrication and application in sample preparation techniques	137
Analytical and biomedical applications of microfluidics in traditional Chinese medicine research	137
Micro- and nanoscale sensing of volatile organic compounds for early-stage cancer diagnosis	136
Concomitant presence of nanosized plastics and metal(loid)s: is there cause for alarm? State-of-the-art and recommendations for future studies	136
From exogenous to endogenous: Advances in in vivo sampling in living systems	134
High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations	129
Microscale thermophoresis (MST) and spectral shift (SpS) in drug discovery	128
Advancements in magnetic aptasensors: Recent progress and future trends in biosensor technology	127
Novel developments in capillary electrophoresis miniaturization, sampling, detection and portability: An overview of the last decade	125
Advances in interferometric sensors for the detection of food contaminants	123
Single-cell spatial (scs) omics: Recent developments in data analysis	120
Greenness of analytical methods for the study of metal-containing nanoparticles in biomedical samples, personal care products and food	120
Optical biosensors utilising viral receptors ACE2 and ACE2 mimics	118
Mapping micro(nano)plastics in various organ systems: Their emerging links to human diseases?	117
Toxicity mechanisms and alleviation strategies of micro/nanoplastics to animals: A review	115

Advancements in detection techniques for per- and polyfluoroalkyl substances: A comprehensive review	115
Recent advances in flexible sensors: From sensing materials to detection modes	113
Advance on the sample preparation and analytical methods for water disinfection byproducts	110
Galectins detection for the diagnosis of chronic diseases: An emerging biosensor approach	108
Advances and challenges in the selective extraction of low molecular weight carbohydrates using ionic liquids and deep eutectic solvents	105
High-throughput optical assays for sensing serine hydrolases in living systems and their applications	105
Recent advances in metal–organic frameworks as emerging platforms for immunoassays	104
Electrochemical sensing of human hormones	104
Recent developments and future perspectives of chiral liquid chromatography for food safety and quality	104
Nanofibers prepared from synthetic polymers and biopolymers as advanced extraction materials for sample preparation prior to liquid chromatography	103
CRISPR-Cas assisted diagnostics: A broad application biosensing approach	103
On-line supercritical fluid extraction-supercritical fluid chromatography (SFE-SFC) at a glance: A coupling story	100
Recent advancements in biosensors for diagnosis of ovarian cancer: Analytical approaches	100
Molecularly imprinted polymer-modified carbon paste electrodes (MIP-CPE): A review on sensitive electrochemical sensors for pharmaceutical determinations	100
Current issues and perspectives in nanosensors-based artificial olfactory systems for breath diagnostics and environmental exposure monitoring	100
Mass spectrometry based metabolomics of volume-restricted in-vivo brain samples: Actual status and the way forward	99
Applications of nanomaterial-based chemiluminescence sensors in environmental analysis	99
Playing with biological selectivity: Antimicrobial peptides and bacteriophages-based optical biosensors for pathogenic bacteria detection	97
Advances in optical devices for the detection of contaminants in food and water	95
Recent advances in cell membrane-coated technology for drug discovery from natural products	95
Microneedle wearables in advanced microsystems: Unlocking next-generation biosensing with AI	94
A comprehensive review on ecological effects of microplastic pollution: An interaction with pollutants in the ecosystems and future perspectives	93
Advances in imaging techniques for real-time microbial visualization in wastewater treatment reactors: Challenges, applications, and process optimization	92
Deciphering the research of Micro(nano)plastics: An in-depth bibliometric expedition into ecotoxicological impacts and research trends	91
High-throughput mass spectrometry imaging of biological systems: Current approaches and future directions	91
Novel sorptive extraction techniques in bioanalysis evaluated by Blue Applicability Grade Index: The paradigm of fabric phase sorptive extraction and capsule phase microextraction	90
Ion mobility Mass Spectrometry for Glycomics: Challenges and Opportunities When Met with Artificial Intelligence	90
Cellulose immobilization strategies for paper-based immunoassays	90
Applications of metal organic frameworks in point of care testing	89
A critical review of acrylamide green extraction and determination in food matrices: Current insights and future perspectives	89
Emerging single-cell microfluidic technology for microbiology	89
Analytical performance of electrochemical surface-enhanced Raman spectroscopy: A critical review	88
Synergizing Machine Learning and fluorescent biomolecules: A new era in sensing platforms	88
Innovative nanozyme-based detection methods for biomarkers in interstitial fluid	87
Editorial Board	87
Tracing per- and polyfluoroalkyl substances (PFASs) in the aquatic environment: Target analysis and beyond	85
Optical microscopic and spectroscopic detection of exosomes	84
Neonatal point-of-care testing	84
Recent advancements in polyaniline-based biosensors for diagnosis of cancers: A comprehensive review	83
Evolution in understandings of the design, optimization, and application of sorbent-based extraction devices	83
Nanomaterial-based chemiluminescence systems for tracing of reactive oxygen species in biosensors	82
Bio-inspired approaches for explosives detection	81
Machine learning-assisted carbon dots synthesis and analysis: State of the art and future directions	80
Fluorogenic toolbox for visualizing protein aggregation: From designing principles to biological application	79
Fluorescent nanozymes: Emerging versatile materials advancing analytical chemistry	79
Advancement in exosome isolation and label-free detection towards clinical diagnosis	79
Liquid crystal-based biosensors as lab-on-chip tools: Promising for future on-site detection test kits	78
Recent chemical mixing devices for time-resolved serial femtosecond crystallography	78
Advances in analytical technologies detecting and characterizing noncovalent interactions for fragment-based drug discovery	77
Analytical methods for biomonitoring organic chemical hazards in saliva: A systematic review	77

Probing protein higher-order structures by native capillary electrophoresis-mass spectrometry	77
Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19	76
Rediscovering similarity analysis of analytical signal: A not well-known mainstay of chemometrics	75
Recent advances in single-entity electrochemistry for metal nanoparticle, nanodroplet, and bio-entity analysis	74
Comprehensive approaches to expanding CRISPR biosensor applications beyond nucleic acid targets	72
Recent developments of small-molecule fluorescent probes for the detection of hydroxyl radical in biological systems	72
The multipurpose application of resazurin in micro-analytical techniques: Trends from the microbial, catalysis and single molecule detection assays	71
Microfluidics for chiral separation of biomolecules	71
Recent advances in electrochemical sensing of cocaine: A review	71
Mass spectrometry for structural elucidation and sequencing of carbohydrates	71
Recent advances in centrifugal microfluidic chip-based loop-mediated isothermal amplification	71
Recent developments in sample pretreatment techniques for the determination of fluoroquinolones in foods	70
Potential applications and challenges of novel ambient ionization mass spectrometric techniques in the emergency care for acute poisoning	69
Recent trends and advancements in electrochemiluminescence biosensors for human virus detection	68
Hydrogel sorbent-based sample preparation processes as green alternatives for the extraction of organic contaminants followed by chromatographic analysis	68
The highest yield, or greener solvents? Latest trends in quercetin extraction methods	67
Exhaled volatile organic compounds and respiratory disease: Recent progress and future outlook	67
Recent advances towards the use of deep eutectic solvents and cyclodextrins in the extraction of food contaminants: From traditional sample pretreatment techniques to green microextraction and beyond	67
Microplastic aging processes: Environmental relevance and analytical implications	66
Trends in electrochemical nanosensors for the analysis of antioxidants	66
Recent advances on graphene and graphene oxide as extraction materials in solid-phase (micro)extraction	66
Editorial Board	65
Recent trends in analytical measures of microplastic in soil and toxicopathological risk assessment in earthworms	65
Capillary electrophoresis and Raman: Can we ever expect light at the end of the tunnel?	65
Corrigendum to “Combining chemometrics and paper-based analytical devices for sensing: An overview” [TrAC. Trends Anal. Chem. 164 (2023) 117091]	65
Sample preparation and mass spectrometry for determining mycotoxins, hazardous fungi, and their metabolites in the environment, food, and healthcare	65
Advances in gas pressure-based portable biosensing	65
Boosting comprehensive two-dimensional chromatography with artificial intelligence: Application to food-omics	65
Application of chemometrics and related advanced data handling in chemical separations	65
The aerobiological pathway of natural respiratory viral aerosols	64
Development of biomimetic phospholipid membrane chromatography for drug discovery: A comprehensive review	64
Functional materials and chemicals in electromembrane extraction	63
Rapid in-situ synthesis of metal organic frameworks for biosensors	63
Microplastics in soil aggregates: Analytical methods, occurrence patterns, impact analyses and removal approaches	62
Early-diagnosis of major depressive disorder: From biomarkers to point-of-care testing	62
Enantioselective separation techniques in forensic analysis and clinical toxicology	62
Fate and impact of nanoplastics in the human digestive environment after oral exposure: A common challenge for toxicology and chemistry	61
Green photonic biosensing: Approaching sustainability in point-of-care diagnostics	61
Advances in X-ray neuroimaging: Bridging scales from molecular to organ architectures	61
3D printed microfluidics for bioanalysis: A review of recent advancements and applications	61
Towards a rational and efficient risk assessment for microplastics	61
Will data analytics revolution finally bring SERS to the clinic?	61
Recent advances of aptamer based sensors for aflatoxins	61
Recent progress in microfluidic biosensors with different driving forces	61
Recent progress and challenges in biosensing of carcinoembryonic antigen	60
Microplastics and nanoplastics in food, water, and beverages; part I. occurrence	59
Biomedical application of hyperbranched polymers: Recent Advances and challenges	59
Towards a harmonized identification scoring system in LC-HRMS/MS based non-target screening (NTS) of emerging contaminants	59
Emerging ELISA derived technologies for in vitro diagnostics	59
Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment	59
Recent advances in droplet microfluidics for single-cell analysis	59
Magnetic-based microextraction systems for the determination of emerging contaminants in environmental liquid samples	59
Determination and assessment of contamination of toxic chemical elements in soils – Review	58
Recent advances in separation methods for characterization of glutathione metabolism and dietary supplementation	58
Metal-organic frameworks as an alternative smart sensing platform for designing molecularly imprinted electrochemical sensors	58
Nanotechnology-assisted microfluidic systems for chemical sensing, biosensing, and bioanalysis	58
Point of care testing of sports biomarkers: Potential applications, recent advances and future outlook	58
Sensitive enzyme-free electrochemical sensors for the detection of pesticide residues in food and water	57
Editorial Board	57
Recent advances in nano/microfabricated substrate platforms and artificial intelligence for practical surface-enhanced Raman scattering-based bioanalysis	57
Recent advances in metal/covalent organic framework-based materials for photoelectrochemical sensing applications	57
Transient OCP-apatite epitaxy controls bone mineralization. An X-ray total scattering study	56
Recent advances in organelle-specific two-photon small-molecule fluorescent probes for bioanalysis in live tissues	56
Caenorhabditis elegans (C. elegans) sample preparation for metabolomics and lipidomics analysis – A review	56
Capillary isoelectric focusing – The role of markers of isoelectric point and recent applications in the field	56
Raman scattering applied to human breath analysis	56
Recent progress in molecular diagnostics: The synergy of rolling circle amplification and CRISPR/Cas systems (2018–2024) – A concise review	56
Lateral flow assays for food analyses: Food contaminants, allergens, toxins, and beyond	56
Corrigendum to “Molecularly imprinted polymers for the detection of volatile biomarkers” [Trends Anal. Chem. 177 (2024) 117783]	56
Nano-engineered screen-printed electrodes: A dynamic tool for detection of viruses	55
Portable X-ray fluorescence (pXRF) as a powerful and trending analytical tool for in situ food samples analysis: A comprehensive review of application - State of the art	55
Surface molecularly imprinted polymer nanocatalytic probes for scattering spectral analysis	55
Recent advances of chiral metal-organic frameworks in analytic chemistry	55
Membrane inlet mass spectrometry (MIMS) for analysis of water disinfection byproducts: Recent advances	55
Modern automated sample preparation for the determination of organic compounds: A review on robotic and on-flow systems	55
A review of organic aerosol speciation by comprehensive two-dimensional gas chromatography	55
Portable sensors in precision agriculture: Assessing advances and challenges in soil nutrient determination	54
Polymer inclusion membranes based Optode: Recent advances and perspectives	54
From untargeted chemical profiling to peak tables – A fully automated AI driven approach to untargeted GC-MS	54
Sample preparation of polar metabolites in biological samples: Methodologies and technological insights	54

Nanomaterials meet microfluidics: Improved analytical methods and high-throughput synthetic approaches	53
Synthesis and characterization of TiO2 nanomaterials for sensing environmental volatile compounds (VOCs): A review	53
Untargeted chromatographic methods coupled with chemometric strategies for the analysis of food and related samples	53
Foodomics in health: Advanced techniques for studying the bioactive role of foods	53
Recent advancements in nucleic acid detection with microfluidic chip for molecular diagnostics	52
Single-cell metabolite analysis by electrospray ionization mass spectrometry	52
Development of laser-induced breakdown spectroscopy based spectral tandem technology: A topical review	51
Deep eutectic solvents for microextraction of endocrine disruptor contaminants from water and food: Review	51
Nanomaterials-based electrochemical sensors and biosensors for the detection of non-steroidal anti-inflammatory drugs	51
CRISPR biosensing with lateral flow assays for point of care Diagnostics: Overcoming commercial development challenges	51
In situ solid phase microextraction sampling of analytes from living human objects for mass spectrometry analysis	51
Advances in 3D printed sensors for food analysis	51
Modern sorbent-based sample preparation methods for the determination of analytes of forensic interest: A dual-tool approach for evaluation of greenness and practical utility	51
Recent advances in microfluidic devices for foodborne pathogens detection	51
Recent advances on portable sensing and biosensing assays applied for detection of main chemical and biological pollutant agents in water samples: A critical review	51
Editorial Board	50
Recent trends in carbon-based microelectrodes as electrochemical sensors for neurotransmitter detection: A review	50
The twelve goals of circular analytical chemistry	50
Miniaturized solid phase extraction techniques for different kind of pollutants analysis: State of the art and future perspectives – PART 2	50
Current trends of unsustainable plastic production and micro(nano)plastic pollution	50
Radiometric strategy to track nanopesticides: An important approach to understand the fate, mechanisms of action and toxicity	49
Challenges and opportunities in the development of planar potentiometric sensors for point-of-care analysis	49
Corrigendum to “Offline preparative separation methods based on electromigration: An overview and current trends” [Trac. Trends Anal. Chem. 170 (2023) 117428]	49
Plastic problem solved? Environmental implications of synthetic hydrophilic polymers across ecosystem boundaries	49
Advances in the analysis of odorous substances derived from drinking water disinfection	49
Editorial Board	49
Engineered aptamer for the analysis of cells	49
New microextraction techniques in exposome Research: Bridging environmental exposures and human health	49
Recent advances in post-column derivatization: Enhancing sensitivity and selectivity in liquid chromatography analysis	48
Tracking indoor volatile organic compounds with online mass spectrometry	48
Recent advances in technologies toward the development of 2D materials-based electronic noses	48
MOFs/COFs-based hybrids for agricultural sensors: Current state of art and beyond	48
Forensic drug screening by liquid chromatography hyphenated with high-resolution mass spectrometry (LC-HRMS)	48
Polar organic pollutants, micro-nano plastics and nanomaterials: Analytical techniques to reveal the still invisible human physico-chemical exposome	48
Exploring advanced materials: Harnessing the synergy of inverse gas chromatography and artificial vision intelligence	47
Advances of surface-enhanced Raman spectroscopy in exosomal biomarkers analysis	47
Variable electric field and atomic percentage of doping on the displacement process of C20 molecules in a nanotube with molecular dynamics simulation	47
Update of high-intensity ultrasound applications for the extraction of pectin from agri-food by-products	47
An overview of analytical methods for enantiomeric determination of chiral pollutants in environmental samples and biota	47
Recent advances of cellulose nanofiber-based materials in cell culture: From population to single-cell	47
Assessing the availability of trace metals including rare earth elements in deep ocean waters of the Clarion Clipperton Zone, NE Pacific: Application of an in situ DGT passive sampling method	47
Recent advances in microfluidic sensors for nutrients detection in water	47
Porous material-based sorbent coatings in solid-phase microextraction technique: Recent trends and future perspectives	47
Perspectives and challenges in extracellular vesicles untargeted metabolomics analysis	46
Recent advances in microfluidic single-cell analysis and its applications in drug development	46
Thermal shift assay for protein–ligand dissociation constant determination	46
Plasmonic biosensors: Towards fully operative detection platforms for biomedical application and its potential for the diagnosis of autoimmune diseases	46
State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants	46
Advances in nanomaterial-based microfluidic platforms for on-site detection of foodborne bacteria	45
Cutting-edge progress in carbon nanomaterial-functionalized silver nanoparticles for enhanced optical and electrochemical sensing applications	45
Green synthesis and characterization of carbon-based materials for sensitive detection of heavy metal ions	45
Deep eutectic solvents-modified advanced functional materials for pollutant detection in food and the environment	45
Cutting-edge MoS2-Based biosensing platforms for detecting contaminants in food samples	45
Biosensing based on lossy mode resonances	45
Fluorescent probes based on bioorthogonal reactions: Construction strategies and applications	45
Advancements in screening systems for active ingredients in traditional Chinese medicines using ligand fishing technique	45
Biomarkers in the diagnosis of wounds infection: An analytical perspective	44
Updated overview of QuEChERS applications in food, environmental and biological analysis (2020–2023)	44
Staining methodologies for microplastics screening	44
Recent advances and applications of Bi2S3-based composites in photoelectrochemical sensors and biosensors	44
Functionalized magnetic nanoparticles as powerful sorbents and stationary phases for the extraction and chromatographic applications	44
Uric acid biosensors based on molecular recognition: Classifications, advances, and prospects	44
Recent advances in exhaled breath sample preparation technologies for drug of abuse detection	44
The review of nanoplastics in plants: Detection, analysis, uptake, migration and risk	44
Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets	44
Microfluidic trends in drug screening and drug delivery	44
Current materials for miniaturized sample preparation: Recent advances and future trends	44
Emerging trends in green carbon dots coated with molecularly imprinted polymers for sensor platforms	44
Recent progress of gas sensors based on metal oxide composites derived from bimetallic metal-organic frameworks	43
Gold nanoparticles conjugated with fluorophore-labeled DNA: Overview of sensing and imaging applications	43
Advances on constructing functional reticular materials for efficient determination of radionuclides	43
Carbon dots based fluorescence methods for the detections of pesticides and veterinary drugs: Response mechanism, selectivity improvement and application	43
Calibration methods in qualitative analysis	43
Recent advances in responsive lanthanide-doped luminescence nanoprobes in the near-infrared-II window	43
Deep learning for near-infrared spectral data modelling: Hypes and benefits	43
Quantification and mapping of RNA modifications	43
Detection, characterization and imaging of micro- and nanoparticles in biotic tissues by laser-induced breakdown spectroscopy	42
Reticular sensing materials with aggregation-induced emission characteristics	42
A review on environmental isotope analysis of aquatic micropollutants: Recent advances, pitfalls and perspectives	42
Microextraction techniques as versatile platforms for sample preparation of disinfection byproducts from aqueous media: Advances and challenges	42
Polymers modified porous silicon optical (bio)sensors	42
Advanced on-site and in vitro signal amplification biosensors for biomolecule analysis	42
Contribution of supercritical fluid chromatography to serially coupling columns for chiral and achiral separations	42
The role of oxylipins and their validation as biomarkers in the clinical context	42
Review of miniaturized and portable optical emission spectrometry based on microplasma for elemental analysis	42
Reducing uncertainty and confronting ignorance about the potential impacts of microplastic on animals: A critical review	41
Seeing the invisible: Preparative strategies to visualise elusive molecules using mass spectrometry imaging	41
Towards sense and sensitivity-based electrochemical biosensors for liquid biopsy-based breast cancer detection	41
Distance-based detection in analytical flow devices: From gas detection tubes to microfluidic chips and microfluidic paper-based analytical devices	41
Harnessing non-noble metal-doped carbon composites for remediation of phthalate esters contaminated water systems	41
The application of coffee-ring effect in analytical chemistry	41
Trends in bimetallic nanomaterials and methods for fourth-generation glucose sensors	41
Human exposure to micro(nano)plastics: Health risks and analysis methods	41
CRISPR techniques and potential for the detection and discrimination of SARS-CoV-2 variants of concern	41
Prospective analytical role of sensors for environmental screening and monitoring	41