TRAC-Trends in Analytical Chemistry

Article	Citations
Editorial Board	652
Editorial	454
Editorial Board	269
Advance on the sample preparation and analytical methods for water disinfection byproducts	203
Applications of thread-based microfluidics: Approaches and options for detection	180
High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations	146
Microneedle wearables in advanced microsystems: Unlocking next-generation biosensing with AI	143
3D printed microfluidics for cell biological applications	142
Advancements in magnetic aptasensors: Recent progress and future trends in biosensor technology	137
Toxicity mechanisms and alleviation strategies of micro/nanoplastics to animals: A review	133
Concomitant presence of nanosized plastics and metal(loid)s: is there cause for alarm? State-of-the-art and recommendations for future studies	131
Design strategies and applications of responsive metal-based luminescence probes in the bioanalysis	131
Single-cell spatial (scs) omics: Recent developments in data analysis	127
Unique role of molecular imaging probes for viral infection	126
Greenness of analytical methods for the study of metal-containing nanoparticles in biomedical samples, personal care products and food	126
Mass spectrometry based metabolomics of volume-restricted in-vivo brain samples: Actual status and the way forward	125
Current issues and perspectives in nanosensors-based artificial olfactory systems for breath diagnostics and environmental exposure monitoring	125
Nanofibers prepared from synthetic polymers and biopolymers as advanced extraction materials for sample preparation prior to liquid chromatography	124
Optical biosensors utilising viral receptors ACE2 and ACE2 mimics	121
Recent advances in cell membrane-coated technology for drug discovery from natural products	119
Advances in interferometric sensors for the detection of food contaminants	118
High-throughput mass spectrometry imaging of biological systems: Current approaches and future directions	114
Single-molecule detection-based super-resolution imaging in single-cell analysis: Inspiring progress and future prospects	113
On-line supercritical fluid extraction-supercritical fluid chromatography (SFE-SFC) at a glance: A coupling story	113
Playing with biological selectivity: Antimicrobial peptides and bacteriophages-based optical biosensors for pathogenic bacteria detection	112

Multidimensional single-cell analysis: Diverse strategies and emerging applications in the life sciences	111
Hydroxyapatite-based composites as efficient sorbents: Fabrication and application in sample preparation techniques	109
Advances in imaging techniques for real-time microbial visualization in wastewater treatment reactors: Challenges, applications, and process optimization	107
Analytical and biomedical applications of microfluidics in traditional Chinese medicine research	106
Micro- and nanoscale sensing of volatile organic compounds for early-stage cancer diagnosis	104
Galectins detection for the diagnosis of chronic diseases: An emerging biosensor approach	102
Electrochemical sensing of human hormones	98
Advances and challenges in the selective extraction of low molecular weight carbohydrates using ionic liquids and deep eutectic solvents	98
Microscale thermophoresis (MST) and spectral shift (SpS) in drug discovery	97
Advances in optical devices for the detection of contaminants in food and water	97
Mapping micro(nano)plastics in various organ systems: Their emerging links to human diseases?	97
Recent advances in metal–organic frameworks as emerging platforms for immunoassays	96
High-throughput optical assays for sensing serine hydrolases in living systems and their applications	96
Recent developments and future perspectives of chiral liquid chromatography for food safety and quality	95
From exogenous to endogenous: Advances in in vivo sampling in living systems	94
Recent advancements in biosensors for diagnosis of ovarian cancer: Analytical approaches	94
Novel developments in capillary electrophoresis miniaturization, sampling, detection and portability: An overview of the last decade	94
CRISPR-Cas assisted diagnostics: A broad application biosensing approach	93
Advancements in detection techniques for per- and polyfluoroalkyl substances: A comprehensive review	92
Molecularly imprinted polymer-modified carbon paste electrodes (MIP-CPE): A review on sensitive electrochemical sensors for pharmaceutical determinations	92
Applications of nanomaterial-based chemiluminescence sensors in environmental analysis	92
A comprehensive review on ecological effects of microplastic pollution: An interaction with pollutants in the ecosystems and future perspectives	91
Recent advances in flexible sensors: From sensing materials to detection modes	91
Recent advancements in polyaniline-based biosensors for diagnosis of cancers: A comprehensive review	90
Hydrogel sorbent-based sample preparation processes as green alternatives for the extraction of organic contaminants followed by chromatographic analysis	88
Cellulose immobilization strategies for paper-based immunoassays	87
Deciphering the research of Micro(nano)plastics: An in-depth bibliometric expedition into ecotoxicological impacts and research trends	87
Ion mobility Mass Spectrometry for Glycomics: Challenges and Opportunities When Met with Artificial Intelligence	87
Evolution in understandings of the design, optimization, and application of sorbent-based extraction devices	86
The multipurpose application of resazurin in micro-analytical techniques: Trends from the microbial, catalysis and single molecule detection assays	86
Editorial Board	86
Exhaled volatile organic compounds and respiratory disease: Recent progress and future outlook	85
Comprehensive approaches to expanding CRISPR biosensor applications beyond nucleic acid targets	85
Fluorogenic toolbox for visualizing protein aggregation: From designing principles to biological application	84
Tracing per- and polyfluoroalkyl substances (PFASs) in the aquatic environment: Target analysis and beyond	84
Recent developments in sample pretreatment techniques for the determination of fluoroquinolones in foods	84
Microfluidics for chiral separation of biomolecules	82
Machine learning-assisted carbon dots synthesis and analysis: State of the art and future directions	82
Trends in electrochemical nanosensors for the analysis of antioxidants	82
Recent trends and advancements in electrochemiluminescence biosensors for human virus detection	82
Fluorescent nanozymes: Emerging versatile materials advancing analytical chemistry	81
Recent advances in centrifugal microfluidic chip-based loop-mediated isothermal amplification	78
Recent advances in single-entity electrochemistry for metal nanoparticle, nanodroplet, and bio-entity analysis	78
Rediscovering similarity analysis of analytical signal: A not well-known mainstay of chemometrics	78
Neonatal point-of-care testing	77
Mass spectrometry for structural elucidation and sequencing of carbohydrates	77
Microplastic aging processes: Environmental relevance and analytical implications	77
Recent developments of small-molecule fluorescent probes for the detection of hydroxyl radical in biological systems	76
Potential applications and challenges of novel ambient ionization mass spectrometric techniques in the emergency care for acute poisoning	76
Recent chemical mixing devices for time-resolved serial femtosecond crystallography	75

Probing protein higher-order structures by native capillary electrophoresis-mass spectrometry	75
Advances in analytical technologies detecting and characterizing noncovalent interactions for fragment-based drug discovery	75
Emerging single-cell microfluidic technology for microbiology	74
Nanomaterial-based chemiluminescence systems for tracing of reactive oxygen species in biosensors	74
A critical review of acrylamide green extraction and determination in food matrices: Current insights and future perspectives	73
Recent advances in electrochemical sensing of cocaine: A review	71
Advancement in exosome isolation and label-free detection towards clinical diagnosis	71
Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19	71
The highest yield, or greener solvents? Latest trends in quercetin extraction methods	69
Liquid crystal-based biosensors as lab-on-chip tools: Promising for future on-site detection test kits	69
Bio-inspired approaches for explosives detection	69
Analytical methods for biomonitoring organic chemical hazards in saliva: A systematic review	68
Novel sorptive extraction techniques in bioanalysis evaluated by Blue Applicability Grade Index: The paradigm of fabric phase sorptive extraction and capsule phase microextraction	68
Boosting comprehensive two-dimensional chromatography with artificial intelligence: Application to food-omics	67
Analytical performance of electrochemical surface-enhanced Raman spectroscopy: A critical review	66
Recent advances towards the use of deep eutectic solvents and cyclodextrins in the extraction of food contaminants: From traditional sample pretreatment techniques to green microextraction and beyond	66
Optical microscopic and spectroscopic detection of exosomes	65
Recent advances on graphene and graphene oxide as extraction materials in solid-phase (micro)extraction	65
Applications of metal organic frameworks in point of care testing	65
Synergizing Machine Learning and fluorescent biomolecules: A new era in sensing platforms	65
Editorial Board	64
Advances in gas pressure-based portable biosensing	64
Sample preparation and mass spectrometry for determining mycotoxins, hazardous fungi, and their metabolites in the environment, food, and healthcare	63
Capillary electrophoresis and Raman: Can we ever expect light at the end of the tunnel?	63
Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment	63
Metal-organic frameworks as an alternative smart sensing platform for designing molecularly imprinted electrochemical sensors	61
Functional materials and chemicals in electromembrane extraction	61
Application of chemometrics and related advanced data handling in chemical separations	61
Green photonic biosensing: Approaching sustainability in point-of-care diagnostics	61
Enantioselective separation techniques in forensic analysis and clinical toxicology	61
Corrigendum to “Combining chemometrics and paper-based analytical devices for sensing: An overview” [TrAC. Trends Anal. Chem. 164 (2023) 117091]	61
Microplastics in soil aggregates: Analytical methods, occurrence patterns, impact analyses and removal approaches	61
Rapid in-situ synthesis of metal organic frameworks for biosensors	60
Early-diagnosis of major depressive disorder: From biomarkers to point-of-care testing	60
Biomedical application of hyperbranched polymers: Recent Advances and challenges	60
Recent advances in separation methods for characterization of glutathione metabolism and dietary supplementation	60
Nanotechnology-assisted microfluidic systems for chemical sensing, biosensing, and bioanalysis	60
Development of biomimetic phospholipid membrane chromatography for drug discovery: A comprehensive review	59
Recent trends in analytical measures of microplastic in soil and toxicopathological risk assessment in earthworms	59
Fate and impact of nanoplastics in the human digestive environment after oral exposure: A common challenge for toxicology and chemistry	59
Towards a harmonized identification scoring system in LC-HRMS/MS based non-target screening (NTS) of emerging contaminants	59
Recent progress and challenges in biosensing of carcinoembryonic antigen	59
Advances in X-ray neuroimaging: Bridging scales from molecular to organ architectures	58
Towards a rational and efficient risk assessment for microplastics	58
Recent advances in nano/microfabricated substrate platforms and artificial intelligence for practical surface-enhanced Raman scattering-based bioanalysis	58
Point of care testing of sports biomarkers: Potential applications, recent advances and future outlook	57
The aerobiological pathway of natural respiratory viral aerosols	57
Emerging ELISA derived technologies for in vitro diagnostics	57
3D printed microfluidics for bioanalysis: A review of recent advancements and applications	57
Recent progress in microfluidic biosensors with different driving forces	56
Will data analytics revolution finally bring SERS to the clinic?	56
Magnetic-based microextraction systems for the determination of emerging contaminants in environmental liquid samples	56
Sensitive enzyme-free electrochemical sensors for the detection of pesticide residues in food and water	56
Microplastics and nanoplastics in food, water, and beverages; part I. occurrence	56
Recent advances in metal/covalent organic framework-based materials for photoelectrochemical sensing applications	56
Determination and assessment of contamination of toxic chemical elements in soils – Review	55
Recent advances in droplet microfluidics for single-cell analysis	55
Corrigendum to “Molecularly imprinted polymers for the detection of volatile biomarkers” [Trends Anal. Chem. 177 (2024) 117783]	55
Editorial Board	55
A review of organic aerosol speciation by comprehensive two-dimensional gas chromatography	55
Caenorhabditis elegans (C. elegans) sample preparation for metabolomics and lipidomics analysis – A review	55
Raman scattering applied to human breath analysis	55
Polymer inclusion membranes based Optode: Recent advances and perspectives	55
Recent advances of chiral metal-organic frameworks in analytic chemistry	54
The twelve goals of circular analytical chemistry	54
Transient OCP-apatite epitaxy controls bone mineralization. An X-ray total scattering study	54
Development of laser-induced breakdown spectroscopy based spectral tandem technology: A topical review	54
Deep eutectic solvents for microextraction of endocrine disruptor contaminants from water and food: Review	53
Advances in 3D printed sensors for food analysis	53
Nanomaterials meet microfluidics: Improved analytical methods and high-throughput synthetic approaches	53
Recent advances in microfluidic devices for foodborne pathogens detection	53
Capillary isoelectric focusing – The role of markers of isoelectric point and recent applications in the field	53
Nano-engineered screen-printed electrodes: A dynamic tool for detection of viruses	53
Portable X-ray fluorescence (pXRF) as a powerful and trending analytical tool for in situ food samples analysis: A comprehensive review of application - State of the art	53
Recent advances in organelle-specific two-photon small-molecule fluorescent probes for bioanalysis in live tissues	53
Lateral flow assays for food analyses: Food contaminants, allergens, toxins, and beyond	53
Synthesis and characterization of TiO2 nanomaterials for sensing environmental volatile compounds (VOCs): A review	52
Nanomaterials-based electrochemical sensors and biosensors for the detection of non-steroidal anti-inflammatory drugs	52
Recent advancements in nucleic acid detection with microfluidic chip for molecular diagnostics	52
Foodomics in health: Advanced techniques for studying the bioactive role of foods	51

Recent advances on portable sensing and biosensing assays applied for detection of main chemical and biological pollutant agents in water samples: A critical review	51
Modern sorbent-based sample preparation methods for the determination of analytes of forensic interest: A dual-tool approach for evaluation of greenness and practical utility	51
Recent trends in carbon-based microelectrodes as electrochemical sensors for neurotransmitter detection: A review	51
Recent progress in molecular diagnostics: The synergy of rolling circle amplification and CRISPR/Cas systems (2018–2024) – A concise review	51
Single-cell metabolite analysis by electrospray ionization mass spectrometry	51
Membrane inlet mass spectrometry (MIMS) for analysis of water disinfection byproducts: Recent advances	51
From untargeted chemical profiling to peak tables – A fully automated AI driven approach to untargeted GC-MS	51
Miniaturized solid phase extraction techniques for different kind of pollutants analysis: State of the art and future perspectives – PART 2	50
Untargeted chromatographic methods coupled with chemometric strategies for the analysis of food and related samples	50
Surface-Enhanced Raman Spectroscopy in the Monitoring of Drug Concentrations in Blood	50
Modern automated sample preparation for the determination of organic compounds: A review on robotic and on-flow systems	50
Current trends of unsustainable plastic production and micro(nano)plastic pollution	49
In situ solid phase microextraction sampling of analytes from living human objects for mass spectrometry analysis	49
Portable sensors in precision agriculture: Assessing advances and challenges in soil nutrient determination	49
Editorial Board	48
Editorial Board	48
State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants	48
Recent advances in microfluidic single-cell analysis and its applications in drug development	47
Plastic problem solved? Environmental implications of synthetic hydrophilic polymers across ecosystem boundaries	47
Advances in the analysis of odorous substances derived from drinking water disinfection	47
Biosensing based on lossy mode resonances	47
MOFs/COFs-based hybrids for agricultural sensors: Current state of art and beyond	47
Corrigendum to “Offline preparative separation methods based on electromigration: An overview and current trends” [Trac. Trends Anal. Chem. 170 (2023) 117428]	47
Radiometric strategy to track nanopesticides: An important approach to understand the fate, mechanisms of action and toxicity	47
Recent advances of cellulose nanofiber-based materials in cell culture: From population to single-cell	47
Perspectives and challenges in extracellular vesicles untargeted metabolomics analysis	46
Engineered aptamer for the analysis of cells	45
Plasmonic biosensors: Towards fully operative detection platforms for biomedical application and its potential for the diagnosis of autoimmune diseases	45
Recent advances in exhaled breath sample preparation technologies for drug of abuse detection	45
Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets	45
Assessing the availability of trace metals including rare earth elements in deep ocean waters of the Clarion Clipperton Zone, NE Pacific: Application of an in situ DGT passive sampling method	45
Green synthesis and characterization of carbon-based materials for sensitive detection of heavy metal ions	45
Recent advances in post-column derivatization: Enhancing sensitivity and selectivity in liquid chromatography analysis	45
Variable electric field and atomic percentage of doping on the displacement process of C20 molecules in a nanotube with molecular dynamics simulation	45
Cutting-edge MoS2-Based biosensing platforms for detecting contaminants in food samples	45
Uric acid biosensors based on molecular recognition: Classifications, advances, and prospects	44
Microfluidic trends in drug screening and drug delivery	44
Update of high-intensity ultrasound applications for the extraction of pectin from agri-food by-products	44
Fluorescent probes based on bioorthogonal reactions: Construction strategies and applications	44
Biomarkers in the diagnosis of wounds infection: An analytical perspective	44
Engineering activatable nanoprobes based on time-resolved luminescence for chemo/biosensing	44
Challenges and opportunities in the development of planar potentiometric sensors for point-of-care analysis	44
Cutting-edge progress in carbon nanomaterial-functionalized silver nanoparticles for enhanced optical and electrochemical sensing applications	44
Forensic drug screening by liquid chromatography hyphenated with high-resolution mass spectrometry (LC-HRMS)	44
Exploring advanced materials: Harnessing the synergy of inverse gas chromatography and artificial vision intelligence	43
Functionalized magnetic nanoparticles as powerful sorbents and stationary phases for the extraction and chromatographic applications	43
Advances of surface-enhanced Raman spectroscopy in exosomal biomarkers analysis	43
An overview of analytical methods for enantiomeric determination of chiral pollutants in environmental samples and biota	43
Porous material-based sorbent coatings in solid-phase microextraction technique: Recent trends and future perspectives	43
Deep learning for near-infrared spectral data modelling: Hypes and benefits	43
Thermal shift assay for protein–ligand dissociation constant determination	42
Recent progress of gas sensors based on metal oxide composites derived from bimetallic metal-organic frameworks	42
Updated overview of QuEChERS applications in food, environmental and biological analysis (2020–2023)	42
Functionalized magnetic nanoparticles for the separation and purification of proteins and peptides	42
Emerging trends in green carbon dots coated with molecularly imprinted polymers for sensor platforms	42
The review of nanoplastics in plants: Detection, analysis, uptake, migration and risk	42
Advancements in screening systems for active ingredients in traditional Chinese medicines using ligand fishing technique	42
Nonlinear optical characterization of pharmaceutical formulations	42
Advances in nanomaterial-based microfluidic platforms for on-site detection of foodborne bacteria	42
Carbon dots based fluorescence methods for the detections of pesticides and veterinary drugs: Response mechanism, selectivity improvement and application	42
Recent advances in microfluidic sensors for nutrients detection in water	42
Tracking indoor volatile organic compounds with online mass spectrometry	42
Current materials for miniaturized sample preparation: Recent advances and future trends	42
Staining methodologies for microplastics screening	41
Deep eutectic solvents-modified advanced functional materials for pollutant detection in food and the environment	41
Recent advances in technologies toward the development of 2D materials-based electronic noses	41
Recent advances and applications of Bi2S3-based composites in photoelectrochemical sensors and biosensors	41
Polymers modified porous silicon optical (bio)sensors	41
Polar organic pollutants, micro-nano plastics and nanomaterials: Analytical techniques to reveal the still invisible human physico-chemical exposome	41
Calibration methods in qualitative analysis	40
Nucleic acid-aided molecular amplification techniques for food microorganism detection	40
Human exposure to micro(nano)plastics: Health risks and analysis methods	40
Reticular sensing materials with aggregation-induced emission characteristics	40
Review of miniaturized and portable optical emission spectrometry based on microplasma for elemental analysis	40
Detection, characterization and imaging of micro- and nanoparticles in biotic tissues by laser-induced breakdown spectroscopy	40
Recent advances of upconversion nanoparticles-based lateral flow assays for point-of-care testing	40
Two-photon fluorescent probes for quantitative bio-imaging analysis in live tissues	40
Dual/Multi-responsive fluorogenic probes for multiple analytes in mitochondria: From design to applications	40
Prospective analytical role of sensors for environmental screening and monitoring	40
Microextraction techniques as versatile platforms for sample preparation of disinfection byproducts from aqueous media: Advances and challenges	40
Contribution of supercritical fluid chromatography to serially coupling columns for chiral and achiral separations	40
CRISPR techniques and potential for the detection and discrimination of SARS-CoV-2 variants of concern	40
Towards sense and sensitivity-based electrochemical biosensors for liquid biopsy-based breast cancer detection	39
Distance-based detection in analytical flow devices: From gas detection tubes to microfluidic chips and microfluidic paper-based analytical devices	39
Nanomaterial-based microfluidic systems for cancer biomarker detection: Recent applications and future perspectives	39
A review on environmental isotope analysis of aquatic micropollutants: Recent advances, pitfalls and perspectives	39
Trends in bimetallic nanomaterials and methods for fourth-generation glucose sensors	39
Protein-mediated fluorescent probes for bioimaging and biosensing: From fundamentals to applications	39
The role of oxylipins and their validation as biomarkers in the clinical context	38
Gold nanoparticles conjugated with fluorophore-labeled DNA: Overview of sensing and imaging applications	38
Enzyme-catalyzed molecular MR imaging of tumors	38
Recent advances in laser-induced breakdown spectroscopy quantification: From fundamental understanding to data processing	38
Reducing uncertainty and confronting ignorance about the potential impacts of microplastic on animals: A critical review	38
Recent advances in responsive lanthanide-doped luminescence nanoprobes in the near-infrared-II window	38
Mass spectrometry detection of environmental microplastics: Advances and challenges	38