TRAC-Trends in Analytical Chemistry

Article	Citations
Editorial Board	455
Editorial Board	293
Editorial	248
Unique role of molecular imaging probes for viral infection	205
Recent advances in metal–organic frameworks as emerging platforms for immunoassays	191
High-throughput optical assays for sensing serine hydrolases in living systems and their applications	185
Toxicity mechanisms and alleviation strategies of micro/nanoplastics to animals: A review	185
Optical biosensors utilising viral receptors ACE2 and ACE2 mimics	184
Detection and impact assessment of polylactic acid microplastics in aquatic and sediment systems: Advances in analytical techniques	182
High resolution single-cell transcriptomics towards precision profiling across multi-omics and spatial dimensions	181
Advancing cancer diagnosis through surface plasmon resonance detection of extracellular vesicles	171
Next-generation point-of-care diagnostics for cervical cancer: Integrating programmable biorecognition, nanomaterials, and artificial intelligence	165
CRISPR-Cas assisted diagnostics: A broad application biosensing approach	163
Micro- and nanoscale sensing of volatile organic compounds for early-stage cancer diagnosis	162
Advances and challenges in the selective extraction of low molecular weight carbohydrates using ionic liquids and deep eutectic solvents	159
Emergent analytical strategies and tools to track functional inorganic nanomaterials applied for sustainable agriculture	157
High-throughput mass spectrometry imaging of biological systems: Current approaches and future directions	145
Applications of nanomaterial-based chemiluminescence sensors in environmental analysis	144
Greenness of analytical methods for the study of metal-containing nanoparticles in biomedical samples, personal care products and food	135
Advance on the sample preparation and analytical methods for water disinfection byproducts	133
Applications of thread-based microfluidics: Approaches and options for detection	132
Microscale thermophoresis (MST) and spectral shift (SpS) in drug discovery	131
Microneedle wearables in advanced microsystems: Unlocking next-generation biosensing with AI	128
Recent developments and future perspectives of chiral liquid chromatography for food safety and quality	126
Molecularly imprinted polymer-modified carbon paste electrodes (MIP-CPE): A review on sensitive electrochemical sensors for pharmaceutical determinations	124

Advances in imaging techniques for real-time microbial visualization in wastewater treatment reactors: Challenges, applications, and process optimization	123
Synthesis strategies to bring molecularly imprinted polymers closer to applications	121
Recent advancements in biosensors for diagnosis of ovarian cancer: Analytical approaches	119
Recent advances in cell membrane-coated technology for drug discovery from natural products	119
Analytical and biomedical applications of microfluidics in traditional Chinese medicine research	118
Single-cell spatial (scs) omics: Recent developments in data analysis	118
Advancements in magnetic aptasensors: Recent progress and future trends in biosensor technology	114
Galectins detection for the diagnosis of chronic diseases: An emerging biosensor approach	114
Novel developments in capillary electrophoresis miniaturization, sampling, detection and portability: An overview of the last decade	113
From exogenous to endogenous: Advances in in vivo sampling in living systems	110
Concomitant presence of nanosized plastics and metal(loid)s: is there cause for alarm? State-of-the-art and recommendations for future studies	110
Advances in interferometric sensors for the detection of food contaminants	108
Compositions, sensing mechanisms, and analytical development of infinite coordination polymers in monitoring trace-level pollutants	106
Nanofibers prepared from synthetic polymers and biopolymers as advanced extraction materials for sample preparation prior to liquid chromatography	106
On the road to automation: a comparative review on chemometric strategies for GC-MS data analysis	106
3D printed microfluidics for cell biological applications	104
Design strategies and applications of responsive metal-based luminescence probes in the bioanalysis	101
Multidimensional single-cell analysis: Diverse strategies and emerging applications in the life sciences	101
Single-molecule detection-based super-resolution imaging in single-cell analysis: Inspiring progress and future prospects	100
Application of machine learning to improve the accuracy of electrochemical sensors: A review	100
CRISPR/Cas system for real-time water quality monitoring: Advances and challenges	100
Genetically encoded fluorescent neurotransmitter sensors: A new frontier in molecular diagnostics and real-time brain imaging	100
Current issues and perspectives in nanosensors-based artificial olfactory systems for breath diagnostics and environmental exposure monitoring	96
Sustainable sorbents for dispersive solid-phase extraction in environmental analysis	96
Advances in optical devices for the detection of contaminants in food and water	96
Playing with biological selectivity: Antimicrobial peptides and bacteriophages-based optical biosensors for pathogenic bacteria detection	96
Electrochemical sensing of human hormones	95
Mapping micro(nano)plastics in various organ systems: Their emerging links to human diseases?	95
A comprehensive review on ecological effects of microplastic pollution: An interaction with pollutants in the ecosystems and future perspectives	95
Recent advances in ion mobility instrumentation for targeted analysis	94
Recent advances in flexible sensors: From sensing materials to detection modes	94
Hydroxyapatite-based composites as efficient sorbents: Fabrication and application in sample preparation techniques	94
Advancements in detection techniques for per- and polyfluoroalkyl substances: A comprehensive review	92
High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations	91
Evolution in understandings of the design, optimization, and application of sorbent-based extraction devices	91
Optical microscopic and spectroscopic detection of exosomes	90
Molecular recognition-driven detection of β-Lactoglobulin: Mechanisms, progress and future prospects	90
Recent advancements in polyaniline-based biosensors for diagnosis of cancers: A comprehensive review	89
Recent developments of small-molecule fluorescent probes for the detection of hydroxyl radical in biological systems	89
Trends in electrochemical nanosensors for the analysis of antioxidants	89
Hydrogel sorbent-based sample preparation processes as green alternatives for the extraction of organic contaminants followed by chromatographic analysis	88
Flow-based automated systems coupled with luminescence detection for non-metal determination: A comprehensive review from 2000 till present	88
Emerging single-cell microfluidic technology for microbiology	88
Smart materials as modifiers of capillary electromigration methods in bioanalysis	88
The multipurpose application of resazurin in micro-analytical techniques: Trends from the microbial, catalysis and single molecule detection assays	87
Deciphering the research of Micro(nano)plastics: An in-depth bibliometric expedition into ecotoxicological impacts and research trends	87
Fluorogenic toolbox for visualizing protein aggregation: From designing principles to biological application	86
Advancements of multiple template-based molecularly imprinted polymers (mt-MIPs) in deep eutectic solvents (DESs): Towards greener imprinting approaches	86
Direct RNA modification mapping: Technological advances, gaps, and emerging trends	86
Comprehensive approaches to expanding CRISPR biosensor applications beyond nucleic acid targets	86

Novel sorptive extraction techniques in bioanalysis evaluated by Blue Applicability Grade Index: The paradigm of fabric phase sorptive extraction and capsule phase microextraction	85
Cellulose immobilization strategies for paper-based immunoassays	85
Advancement in exosome isolation and label-free detection towards clinical diagnosis	85
State of the art and perspectives of improving antibody performance in food immunosensors	85
Analytical performance of electrochemical surface-enhanced Raman spectroscopy: A critical review	84
Advances in analytical technologies detecting and characterizing noncovalent interactions for fragment-based drug discovery	84
Probing protein higher-order structures by native capillary electrophoresis-mass spectrometry	83
Ion mobility Mass Spectrometry for Glycomics: Challenges and Opportunities When Met with Artificial Intelligence	83
Exhaled volatile organic compounds and respiratory disease: Recent progress and future outlook	83
Recent developments in sample pretreatment techniques for the determination of fluoroquinolones in foods	82
Tracing per- and polyfluoroalkyl substances (PFASs) in the aquatic environment: Target analysis and beyond	81
Recent chemical mixing devices for time-resolved serial femtosecond crystallography	81
Microplastic aging processes: Environmental relevance and analytical implications	81
Recent advances in centrifugal microfluidic chip-based loop-mediated isothermal amplification	81
Recent advances in electrochemical sensing of cocaine: A review	81
Recent advances in single-entity electrochemistry for metal nanoparticle, nanodroplet, and bio-entity analysis	80
The highest yield, or greener solvents? Latest trends in quercetin extraction methods	80
Recent advances towards the use of deep eutectic solvents and cyclodextrins in the extraction of food contaminants: From traditional sample pretreatment techniques to green microextraction and beyond	79
Towards clinical application: Emerging strategies for ultrasensitive and selective miRNA detection	79
Microfluidics for chiral separation of biomolecules	79
Single-molecule microscopy for precision medicine and diagnostics	78
Recent trends and advancements in electrochemiluminescence biosensors for human virus detection	77
Nanomaterial-based chemiluminescence systems for tracing of reactive oxygen species in biosensors	77
MXene-based composites: A new generation material for the sample preparation and pre-concentration of the traces of organic species in environmental samples: A comprehensive review	77
Analytical methods for biomonitoring organic chemical hazards in saliva: A systematic review	76
Recent advances on graphene and graphene oxide as extraction materials in solid-phase (micro)extraction	76
A critical review of acrylamide green extraction and determination in food matrices: Current insights and future perspectives	75
Covalent organic frameworks for next-generation biomedicine: from rational design to multimodal theranostics	74
Fluorescent sensors for anthelmintic drug detection: Advances in materials, mechanisms, and analytical applications	74
Synergizing Machine Learning and fluorescent biomolecules: A new era in sensing platforms	74
Innovative nanozyme-based detection methods for biomarkers in interstitial fluid	73
Rediscovering similarity analysis of analytical signal: A not well-known mainstay of chemometrics	73
Critical review of analytical methods for antifouling paint particles in marine systems	73
Potential applications and challenges of novel ambient ionization mass spectrometric techniques in the emergency care for acute poisoning	73
Boosting comprehensive two-dimensional chromatography with artificial intelligence: Application to food-omics	72
Advances in protein sequencing: Techniques, challenges and prospects	72
Fluorescent nanozymes: Emerging versatile materials advancing analytical chemistry	71
Applications of metal organic frameworks in point of care testing	71
Neonatal point-of-care testing	71
Machine learning-assisted carbon dots synthesis and analysis: State of the art and future directions	70
Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19	70
Editorial Board	70
Capillary electrophoresis and Raman: Can we ever expect light at the end of the tunnel?	69
Application of chemometrics and related advanced data handling in chemical separations	69
Advances in detection technologies for RNA m6A modifications and related enzymes: Strategies and applications	68
Fate and impact of nanoplastics in the human digestive environment after oral exposure: A common challenge for toxicology and chemistry	68
Will data analytics revolution finally bring SERS to the clinic?	68
Trends in melatonin sensing technology for biomedical applications:Precision sleep medicine and beyond	68
Early-diagnosis of major depressive disorder: From biomarkers to point-of-care testing	68
Corrigendum to “Combining chemometrics and paper-based analytical devices for sensing: An overview” [TrAC. Trends Anal. Chem. 164 (2023) 117091]	68
The aerobiological pathway of natural respiratory viral aerosols	67
Advances in small organic molecule fluorescent probes for formaldehyde detection and imaging in pathophysiological processes: A comprehensive review	67
Magnetic-based microextraction systems for the determination of emerging contaminants in environmental liquid samples	67
Development of biomimetic phospholipid membrane chromatography for drug discovery: A comprehensive review	67
Sample preparation and mass spectrometry for determining mycotoxins, hazardous fungi, and their metabolites in the environment, food, and healthcare	67
Microplastics in soil aggregates: Analytical methods, occurrence patterns, impact analyses and removal approaches	66
Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment	66
Advances in X-ray neuroimaging: Bridging scales from molecular to organ architectures	66
Advances in mass spectrometry-based strategies for analyzing sialic acid linkage isomers	66
3D printed microfluidics for bioanalysis: A review of recent advancements and applications	66
Analytical frontiers in disinfection byproducts research: Linking formation, transformation, and antibiotic resistance through advanced mass spectrometry, isotopic, and sensing tools	65
Split technology in CRISPR-Cas system for precision genome manipulation and diagnostics	65
Analytical approaches for detecting biocides in aquatic environments: Advances and challenges	65
Recent advances in nano/microfabricated substrate platforms and artificial intelligence for practical surface-enhanced Raman scattering-based bioanalysis	65
Rapid in-situ synthesis of metal organic frameworks for biosensors	65
Recent trends in analytical measures of microplastic in soil and toxicopathological risk assessment in earthworms	64
Green photonic biosensing: Approaching sustainability in point-of-care diagnostics	64
Emerging ELISA derived technologies for in vitro diagnostics	64
Recent advancements in dual modality biosensors for detecting disease causing pathogens	64
The interdiscipline rendezvous of aptamers and radionuclides: Advances, challenges and prospects	64
Recent advances in separation methods for characterization of glutathione metabolism and dietary supplementation	64
Nanotechnology-assisted microfluidic systems for chemical sensing, biosensing, and bioanalysis	64
Enantioselective separation techniques in forensic analysis and clinical toxicology	63
Recent advances in metal/covalent organic framework-based materials for photoelectrochemical sensing applications	63
Sensitive enzyme-free electrochemical sensors for the detection of pesticide residues in food and water	63
Advances in gas pressure-based portable biosensing	63
Towards a rational and efficient risk assessment for microplastics	63
Recent advances of aptamer based sensors for aflatoxins	63
Determination and assessment of contamination of toxic chemical elements in soils – Review	62
Towards a harmonized identification scoring system in LC-HRMS/MS based non-target screening (NTS) of emerging contaminants	61

Recent progress and challenges in biosensing of carcinoembryonic antigen	61
Recent progress in microfluidic biosensors with different driving forces	61
Recent advances in droplet microfluidics for single-cell analysis	61
Transient OCP-apatite epitaxy controls bone mineralization. An X-ray total scattering study	60
Recent advance in nucleic acid amplification-based surface-enhanced Raman scattering for in vitro and in vivo biosensing	60
Polymer inclusion membranes based Optode: Recent advances and perspectives	60
Editorial Board	60
Nanopore sensing: current progress and future challenges tackled by nanofluidic devices	60
Synthesis and characterization of TiO2 nanomaterials for sensing environmental volatile compounds (VOCs): A review	60
Microplastics and nanoplastics in food, water, and beverages; part I. occurrence	60
Advances in single extracellular vesicle characterization and multiplexed profiling	60
Raman scattering applied to human breath analysis	59
Recent advances in microfluidic devices for foodborne pathogens detection	59
Corrigendum to “Molecularly imprinted polymers for the detection of volatile biomarkers” [Trends Anal. Chem. 177 (2024) 117783]	59
Surface-enhanced Raman spectroscopy in the monitoring of drug concentrations in blood	59
Modern automated sample preparation for the determination of organic compounds: A review on robotic and on-flow systems	59
Dual-target fluorescence probes: A new frontier in cardiovascular disease diagnosis	59
Membrane inlet mass spectrometry (MIMS) for analysis of water disinfection byproducts: Recent advances	59
Editorial Board	59
A review of organic aerosol speciation by comprehensive two-dimensional gas chromatography	59
Recent advances in organelle-specific two-photon small-molecule fluorescent probes for bioanalysis in live tissues	59
Trends in nucleic acids and non-nucleic acids nanostructures-enhanced site-specific DNA methylation biosensing	58
Portable X-ray fluorescence (pXRF) as a powerful and trending analytical tool for in situ food samples analysis: A comprehensive review of application - State of the art	58
Deep eutectic solvents for microextraction of endocrine disruptor contaminants from water and food: Review	58
Miniaturized solid phase extraction techniques for different kind of pollutants analysis: State of the art and future perspectives – PART 2	58
Advances in 3D printed sensors for food analysis	57
Modern sorbent-based sample preparation methods for the determination of analytes of forensic interest: A dual-tool approach for evaluation of greenness and practical utility	57
The twelve goals of circular analytical chemistry	57
Recent progress in molecular diagnostics: The synergy of rolling circle amplification and CRISPR/Cas systems (2018–2024) – A concise review	57
Minimalist nanobody architecture: A double-edged sword for immunological analysis	57
Caenorhabditis elegans (C. elegans) sample preparation for metabolomics and lipidomics analysis – A review	57
Intelligent terahertz data analysis in agriculture: A systematic review of AI-driven approaches	56
Portable sensors in precision agriculture: Assessing advances and challenges in soil nutrient determination	56
Sample preparation of polar metabolites in biological samples: Methodologies and technological insights	56
Recent advances of chiral metal-organic frameworks in analytic chemistry	56
Recent developments of ECL mechanisms study and their applications	56
Surface molecularly imprinted polymer nanocatalytic probes for scattering spectral analysis	56
Recent advancements in nucleic acid detection with microfluidic chip for molecular diagnostics	56
Untargeted chromatographic methods coupled with chemometric strategies for the analysis of food and related samples	55
Exploiting the penetration depth of XRF and NIR radiation: from 2D to 3D spectral imaging	55
Development of laser-induced breakdown spectroscopy based spectral tandem technology: A topical review	54
Capillary isoelectric focusing – The role of markers of isoelectric point and recent applications in the field	54
Editorial Board	54
Advances in solid-phase microextraction for detecting endocrine disrupting compounds in environmental and biological matrices	54
Lateral flow assays for food analyses: Food contaminants, allergens, toxins, and beyond	54
Variable electric field and atomic percentage of doping on the displacement process of C20 molecules in a nanotube with molecular dynamics simulation	54
CRISPR biosensing with lateral flow assays for point of care Diagnostics: Overcoming commercial development challenges	54
Editorial Board	54
Current trends of unsustainable plastic production and micro(nano)plastic pollution	54
New microextraction techniques in exposome Research: Bridging environmental exposures and human health	53
Deep eutectic solvents-modified advanced functional materials for pollutant detection in food and the environment	53
Recent advances in technologies toward the development of 2D materials-based electronic noses	53
Recent advances in exhaled breath sample preparation technologies for drug of abuse detection	53
Tracking indoor volatile organic compounds with online mass spectrometry	53
Polar organic pollutants, micro-nano plastics and nanomaterials: Analytical techniques to reveal the still invisible human physico-chemical exposome	53
Multi-scenario deployable analysis platform for the detection of illicit pharmaceutical adulteration in dietary supplements	53
Corrigendum to “Offline preparative separation methods based on electromigration: An overview and current trends” [Trac. Trends Anal. Chem. 170 (2023) 117428]	53
Biosensing based on lossy mode resonances	52
Advances of surface-enhanced Raman spectroscopy in exosomal biomarkers analysis	52
Exploring advanced materials: Harnessing the synergy of inverse gas chromatography and artificial vision intelligence	52
Thermal shift assay for protein–ligand dissociation constant determination	52
Editorial Board	52
State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants	52
Emerging trends in green carbon dots coated with molecularly imprinted polymers for sensor platforms	51
Plastic problem solved? Environmental implications of synthetic hydrophilic polymers across ecosystem boundaries	51
Recent advances in microfluidic single-cell analysis and its applications in drug development	51
AI-enhanced CRISPR diagnostics: From gRNA design to Cas protein engineering and signal analytics	51
Lights and shadows of mass spectrometry-based metabolomics studies in cancer diagnosis: is there any marker beyond the literature background noise?	51
Advances in the analysis of odorous substances derived from drinking water disinfection	51
Challenges and opportunities in the development of planar potentiometric sensors for point-of-care analysis	51
Recent advances and applications of Bi2S3-based composites in photoelectrochemical sensors and biosensors	51
Gas–phase sampling and preconcentration of nerve agents: Overview of thermally desorbable materials used	51
Plasmonic biosensors: Towards fully operative detection platforms for biomedical application and its potential for the diagnosis of autoimmune diseases	51
Recent advances in the analytical applications of laccase-like nanozymes	51
Recent advances in microfluidic sensors for nutrients detection in water	50
Staining methodologies for microplastics screening	50
Radiometric strategy to track nanopesticides: An important approach to understand the fate, mechanisms of action and toxicity	50
Ultrasound-assisted microextraction: Advancements, applications, and future directions in analytical chemistry	50
Recent advances of cellulose nanofiber-based materials in cell culture: From population to single-cell	50
Cutting-edge MoS2-Based biosensing platforms for detecting contaminants in food samples	50
Analysis of contaminants of environment and foods by capillary electromigration techniques	50
Cutting-edge progress in carbon nanomaterial-functionalized silver nanoparticles for enhanced optical and electrochemical sensing applications	50
Update of high-intensity ultrasound applications for the extraction of pectin from agri-food by-products	50
Advancements in screening systems for active ingredients in traditional Chinese medicines using ligand fishing technique	49
MOFs/COFs-based hybrids for agricultural sensors: Current state of art and beyond	49
Deep learning for near-infrared spectral data modelling: Hypes and benefits	49
Assessing the availability of trace metals including rare earth elements in deep ocean waters of the Clarion Clipperton Zone, NE Pacific: Application of an in situ DGT passive sampling method	49
Updated overview of QuEChERS applications in food, environmental and biological analysis (2020–2023)	49
Recent progress of gas sensors based on metal oxide composites derived from bimetallic metal-organic frameworks	48
The review of nanoplastics in plants: Detection, analysis, uptake, migration and risk	48
Forensic drug screening by liquid chromatography hyphenated with high-resolution mass spectrometry (LC-HRMS)	48
Triple-color emission ratiometric fluorescence in biochemical sensing analysis; principles, probe fabrication and applications	48
Fluorescent probes based on bioorthogonal reactions: Construction strategies and applications	48
Uric acid biosensors based on molecular recognition: Classifications, advances, and prospects	48
CRISPR/Cas12a-based biosensors for foodborne mycotoxin detection: A review of current technologies and future prospects	48