TRAC-Trends in Analytical Chemistry

Article	Citations
Current issues and perspectives in nanosensors-based artificial olfactory systems for breath diagnostics and environmental exposure monitoring	765
Recent advances in cell membrane-coated technology for drug discovery from natural products	509
Editorial Board	317
Editorial Board	228
A comprehensive review on ecological effects of microplastic pollution: An interaction with pollutants in the ecosystems and future perspectives	189
High-throughput optical assays for sensing serine hydrolases in living systems and their applications	177
3D printed microfluidics for cell biological applications	156
From exogenous to endogenous: Advances in in vivo sampling in living systems	156
Editorial	152
Mass spectrometry based metabolomics of volume-restricted in-vivo brain samples: Actual status and the way forward	151
Micro- and nanoscale sensing of volatile organic compounds for early-stage cancer diagnosis	144
Recent advances in flexible sensors: From sensing materials to detection modes	139
Molecularly imprinted polymer-modified carbon paste electrodes (MIP-CPE): A review on sensitive electrochemical sensors for pharmaceutical determinations	139
Applications of thread-based microfluidics: Approaches and options for detection	139
On-line supercritical fluid extraction-supercritical fluid chromatography (SFE-SFC) at a glance: A coupling story	138
Novel developments in capillary electrophoresis miniaturization, sampling, detection and portability: An overview of the last decade	138
Concomitant presence of nanosized plastics and metal(loid)s: is there cause for alarm? State-of-the-art and recommendations for future studies	136
Unique role of molecular imaging probes for viral infection	131
Recent advances in metal–organic frameworks as emerging platforms for immunoassays	130
Advancements in magnetic aptasensors: Recent progress and future trends in biosensor technology	129
Single-molecule detection-based super-resolution imaging in single-cell analysis: Inspiring progress and future prospects	127
Playing with biological selectivity: Antimicrobial peptides and bacteriophages-based optical biosensors for pathogenic bacteria detection	124
Greenness of analytical methods for the study of metal-containing nanoparticles in biomedical samples, personal care products and food	123
Advances and challenges in the selective extraction of low molecular weight carbohydrates using ionic liquids and deep eutectic solvents	122
Design strategies and applications of responsive metal-based luminescence probes in the bioanalysis	120

High-throughput mass spectrometry imaging of biological systems: Current approaches and future directions	119
Mapping micro(nano)plastics in various organ systems: Their emerging links to human diseases?	118
Nanofibers prepared from synthetic polymers and biopolymers as advanced extraction materials for sample preparation prior to liquid chromatography	114
Hydroxyapatite-based composites as efficient sorbents: Fabrication and application in sample preparation techniques	112
Multidimensional single-cell analysis: Diverse strategies and emerging applications in the life sciences	112
On the road to automation: a comparative review on chemometric strategies for GC-MS data analysis	111
Advance on the sample preparation and analytical methods for water disinfection byproducts	110
Advances in imaging techniques for real-time microbial visualization in wastewater treatment reactors: Challenges, applications, and process optimization	109
Advances in interferometric sensors for the detection of food contaminants	106
Microscale thermophoresis (MST) and spectral shift (SpS) in drug discovery	106
Electrochemical sensing of human hormones	106
Advancing cancer diagnosis through surface plasmon resonance detection of extracellular vesicles	104
Optical biosensors utilising viral receptors ACE2 and ACE2 mimics	103
Recent developments and future perspectives of chiral liquid chromatography for food safety and quality	101
Advancements in detection techniques for per- and polyfluoroalkyl substances: A comprehensive review	100
Toxicity mechanisms and alleviation strategies of micro/nanoplastics to animals: A review	99
Microneedle wearables in advanced microsystems: Unlocking next-generation biosensing with AI	98
Recent advancements in biosensors for diagnosis of ovarian cancer: Analytical approaches	98
High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations	98
Advances in optical devices for the detection of contaminants in food and water	97
CRISPR-Cas assisted diagnostics: A broad application biosensing approach	94
Galectins detection for the diagnosis of chronic diseases: An emerging biosensor approach	94
Analytical and biomedical applications of microfluidics in traditional Chinese medicine research	94
Recent developments in sample pretreatment techniques for the determination of fluoroquinolones in foods	92
Single-cell spatial (scs) omics: Recent developments in data analysis	92
Ion mobility Mass Spectrometry for Glycomics: Challenges and Opportunities When Met with Artificial Intelligence	92
Applications of nanomaterial-based chemiluminescence sensors in environmental analysis	92
Cellulose immobilization strategies for paper-based immunoassays	92
Synergizing Machine Learning and fluorescent biomolecules: A new era in sensing platforms	91
Neonatal point-of-care testing	90
Exhaled volatile organic compounds and respiratory disease: Recent progress and future outlook	90
Machine learning-assisted carbon dots synthesis and analysis: State of the art and future directions	88
Advances in protein sequencing: Techniques, challenges and prospects	87
Smart materials as modifiers of capillary electromigration methods in bioanalysis	85
Innovative nanozyme-based detection methods for biomarkers in interstitial fluid	85
Rediscovering similarity analysis of analytical signal: A not well-known mainstay of chemometrics	85
Hydrogel sorbent-based sample preparation processes as green alternatives for the extraction of organic contaminants followed by chromatographic analysis	84
Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19	84
Microfluidics for chiral separation of biomolecules	83
Potential applications and challenges of novel ambient ionization mass spectrometric techniques in the emergency care for acute poisoning	83
Optical microscopic and spectroscopic detection of exosomes	83
Recent advances in centrifugal microfluidic chip-based loop-mediated isothermal amplification	83
Nanomaterial-based chemiluminescence systems for tracing of reactive oxygen species in biosensors	82
Probing protein higher-order structures by native capillary electrophoresis-mass spectrometry	82
Advances in analytical technologies detecting and characterizing noncovalent interactions for fragment-based drug discovery	81
Editorial Board	81
Trends in electrochemical nanosensors for the analysis of antioxidants	81
Boosting comprehensive two-dimensional chromatography with artificial intelligence: Application to food-omics	80
Analytical methods for biomonitoring organic chemical hazards in saliva: A systematic review	79
Recent advances towards the use of deep eutectic solvents and cyclodextrins in the extraction of food contaminants: From traditional sample pretreatment techniques to green microextraction and beyond	79

Recent advances in electrochemical sensing of cocaine: A review	78
A critical review of acrylamide green extraction and determination in food matrices: Current insights and future perspectives	77
Fluorogenic toolbox for visualizing protein aggregation: From designing principles to biological application	76
Recent chemical mixing devices for time-resolved serial femtosecond crystallography	75
Applications of metal organic frameworks in point of care testing	74
The multipurpose application of resazurin in micro-analytical techniques: Trends from the microbial, catalysis and single molecule detection assays	74
Emerging single-cell microfluidic technology for microbiology	73
Evolution in understandings of the design, optimization, and application of sorbent-based extraction devices	73
Recent advances in single-entity electrochemistry for metal nanoparticle, nanodroplet, and bio-entity analysis	72
The highest yield, or greener solvents? Latest trends in quercetin extraction methods	72
State of the art and perspectives of improving antibody performance in food immunosensors	71
Tracing per- and polyfluoroalkyl substances (PFASs) in the aquatic environment: Target analysis and beyond	71
Recent advances on graphene and graphene oxide as extraction materials in solid-phase (micro)extraction	70
Mass spectrometry for structural elucidation and sequencing of carbohydrates	70
Fluorescent nanozymes: Emerging versatile materials advancing analytical chemistry	70
Deciphering the research of Micro(nano)plastics: An in-depth bibliometric expedition into ecotoxicological impacts and research trends	69
Recent developments of small-molecule fluorescent probes for the detection of hydroxyl radical in biological systems	69
Comprehensive approaches to expanding CRISPR biosensor applications beyond nucleic acid targets	69
Analytical performance of electrochemical surface-enhanced Raman spectroscopy: A critical review	69
Recent trends and advancements in electrochemiluminescence biosensors for human virus detection	69
Recent advancements in polyaniline-based biosensors for diagnosis of cancers: A comprehensive review	68
Novel sorptive extraction techniques in bioanalysis evaluated by Blue Applicability Grade Index: The paradigm of fabric phase sorptive extraction and capsule phase microextraction	68
Microplastic aging processes: Environmental relevance and analytical implications	68
Advancement in exosome isolation and label-free detection towards clinical diagnosis	68
Green photonic biosensing: Approaching sustainability in point-of-care diagnostics	67
Editorial Board	67
Advances in gas pressure-based portable biosensing	67
Rapid in-situ synthesis of metal organic frameworks for biosensors	66
Recent advances of aptamer based sensors for aflatoxins	66
Advances in mass spectrometry-based strategies for analyzing sialic acid linkage isomers	65
Advances in small organic molecule fluorescent probes for formaldehyde detection and imaging in pathophysiological processes: A comprehensive review	64
Microplastics in soil aggregates: Analytical methods, occurrence patterns, impact analyses and removal approaches	63
Determination and assessment of contamination of toxic chemical elements in soils – Review	63
Towards a harmonized identification scoring system in LC-HRMS/MS based non-target screening (NTS) of emerging contaminants	62
Magnetic-based microextraction systems for the determination of emerging contaminants in environmental liquid samples	62
Enantioselective separation techniques in forensic analysis and clinical toxicology	62
Nanotechnology-assisted microfluidic systems for chemical sensing, biosensing, and bioanalysis	62
The aerobiological pathway of natural respiratory viral aerosols	61
Advances in X-ray neuroimaging: Bridging scales from molecular to organ architectures	61
Towards a rational and efficient risk assessment for microplastics	61
Development of biomimetic phospholipid membrane chromatography for drug discovery: A comprehensive review	61
Functional materials and chemicals in electromembrane extraction	61
Recent progress and challenges in biosensing of carcinoembryonic antigen	61
Will data analytics revolution finally bring SERS to the clinic?	61
Corrigendum to “Combining chemometrics and paper-based analytical devices for sensing: An overview” [TrAC. Trends Anal. Chem. 164 (2023) 117091]	61
Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment	61
Recent trends in analytical measures of microplastic in soil and toxicopathological risk assessment in earthworms	61
Recent advances in nano/microfabricated substrate platforms and artificial intelligence for practical surface-enhanced Raman scattering-based bioanalysis	61
3D printed microfluidics for bioanalysis: A review of recent advancements and applications	61
Application of chemometrics and related advanced data handling in chemical separations	61
Recent advances in separation methods for characterization of glutathione metabolism and dietary supplementation	60
Sample preparation and mass spectrometry for determining mycotoxins, hazardous fungi, and their metabolites in the environment, food, and healthcare	60
Metal-organic frameworks as an alternative smart sensing platform for designing molecularly imprinted electrochemical sensors	60
Capillary electrophoresis and Raman: Can we ever expect light at the end of the tunnel?	60
Emerging ELISA derived technologies for in vitro diagnostics	60
Fate and impact of nanoplastics in the human digestive environment after oral exposure: A common challenge for toxicology and chemistry	60
Early-diagnosis of major depressive disorder: From biomarkers to point-of-care testing	60
Microplastics and nanoplastics in food, water, and beverages; part I. occurrence	59
Sensitive enzyme-free electrochemical sensors for the detection of pesticide residues in food and water	59
Recent progress in microfluidic biosensors with different driving forces	59
Modern sorbent-based sample preparation methods for the determination of analytes of forensic interest: A dual-tool approach for evaluation of greenness and practical utility	58
Raman scattering applied to human breath analysis	58
Recent advances in metal/covalent organic framework-based materials for photoelectrochemical sensing applications	58
Transient OCP-apatite epitaxy controls bone mineralization. An X-ray total scattering study	58
Recent advances in droplet microfluidics for single-cell analysis	58
Trends in nucleic acids and non-nucleic acids nanostructures-enhanced site-specific DNA methylation biosensing	57
The twelve goals of circular analytical chemistry	57
Corrigendum to “Molecularly imprinted polymers for the detection of volatile biomarkers” [Trends Anal. Chem. 177 (2024) 117783]	57
Advances in solid-phase microextraction for detecting endocrine disrupting compounds in environmental and biological matrices	57
Surface-enhanced Raman spectroscopy in the monitoring of drug concentrations in blood	57
Surface molecularly imprinted polymer nanocatalytic probes for scattering spectral analysis	57
Portable sensors in precision agriculture: Assessing advances and challenges in soil nutrient determination	57
Recent progress in molecular diagnostics: The synergy of rolling circle amplification and CRISPR/Cas systems (2018–2024) – A concise review	56
Untargeted chromatographic methods coupled with chemometric strategies for the analysis of food and related samples	56
Recent advances in microfluidic devices for foodborne pathogens detection	56
Recent advances in organelle-specific two-photon small-molecule fluorescent probes for bioanalysis in live tissues	56
Miniaturized solid phase extraction techniques for different kind of pollutants analysis: State of the art and future perspectives – PART 2	56
Single-cell metabolite analysis by electrospray ionization mass spectrometry	56
Recent advances of chiral metal-organic frameworks in analytic chemistry	55
Capillary isoelectric focusing – The role of markers of isoelectric point and recent applications in the field	55

Deep eutectic solvents for microextraction of endocrine disruptor contaminants from water and food: Review	55
Polymer inclusion membranes based Optode: Recent advances and perspectives	55
Lateral flow assays for food analyses: Food contaminants, allergens, toxins, and beyond	54
Synthesis and characterization of TiO2 nanomaterials for sensing environmental volatile compounds (VOCs): A review	54
Nano-engineered screen-printed electrodes: A dynamic tool for detection of viruses	54
Caenorhabditis elegans (C. elegans) sample preparation for metabolomics and lipidomics analysis – A review	54
Editorial Board	54
Membrane inlet mass spectrometry (MIMS) for analysis of water disinfection byproducts: Recent advances	53
Advances in 3D printed sensors for food analysis	52
CRISPR biosensing with lateral flow assays for point of care Diagnostics: Overcoming commercial development challenges	52
In situ solid phase microextraction sampling of analytes from living human objects for mass spectrometry analysis	52
A review of organic aerosol speciation by comprehensive two-dimensional gas chromatography	52
Recent advancements in nucleic acid detection with microfluidic chip for molecular diagnostics	51
Nanomaterials-based electrochemical sensors and biosensors for the detection of non-steroidal anti-inflammatory drugs	51
Current trends of unsustainable plastic production and micro(nano)plastic pollution	51
Development of laser-induced breakdown spectroscopy based spectral tandem technology: A topical review	51
From untargeted chemical profiling to peak tables – A fully automated AI driven approach to untargeted GC-MS	51
Foodomics in health: Advanced techniques for studying the bioactive role of foods	51
Recent advances on portable sensing and biosensing assays applied for detection of main chemical and biological pollutant agents in water samples: A critical review	51
Modern automated sample preparation for the determination of organic compounds: A review on robotic and on-flow systems	51
Sample preparation of polar metabolites in biological samples: Methodologies and technological insights	51
Recent trends in carbon-based microelectrodes as electrochemical sensors for neurotransmitter detection: A review	51
Portable X-ray fluorescence (pXRF) as a powerful and trending analytical tool for in situ food samples analysis: A comprehensive review of application - State of the art	50
Advancements in screening systems for active ingredients in traditional Chinese medicines using ligand fishing technique	50
Exploring advanced materials: Harnessing the synergy of inverse gas chromatography and artificial vision intelligence	50
Corrigendum to “Offline preparative separation methods based on electromigration: An overview and current trends” [Trac. Trends Anal. Chem. 170 (2023) 117428]	50
Uric acid biosensors based on molecular recognition: Classifications, advances, and prospects	50
Recent advances in post-column derivatization: Enhancing sensitivity and selectivity in liquid chromatography analysis	50
Plasmonic biosensors: Towards fully operative detection platforms for biomedical application and its potential for the diagnosis of autoimmune diseases	50
Polar organic pollutants, micro-nano plastics and nanomaterials: Analytical techniques to reveal the still invisible human physico-chemical exposome	50
Update of high-intensity ultrasound applications for the extraction of pectin from agri-food by-products	50
New microextraction techniques in exposome Research: Bridging environmental exposures and human health	50
Cutting-edge progress in carbon nanomaterial-functionalized silver nanoparticles for enhanced optical and electrochemical sensing applications	49
Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets	49
Cutting-edge MoS2-Based biosensing platforms for detecting contaminants in food samples	49
Challenges and opportunities in the development of planar potentiometric sensors for point-of-care analysis	49
The review of nanoplastics in plants: Detection, analysis, uptake, migration and risk	49
Microfluidic trends in drug screening and drug delivery	48
Perspectives and challenges in extracellular vesicles untargeted metabolomics analysis	48
Engineered aptamer for the analysis of cells	48
State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants	48
Porous material-based sorbent coatings in solid-phase microextraction technique: Recent trends and future perspectives	48
Deep eutectic solvents-modified advanced functional materials for pollutant detection in food and the environment	48
Advances of surface-enhanced Raman spectroscopy in exosomal biomarkers analysis	48
Current materials for miniaturized sample preparation: Recent advances and future trends	48
Recent advances in microfluidic single-cell analysis and its applications in drug development	47
Editorial Board	47
Recent progress of gas sensors based on metal oxide composites derived from bimetallic metal-organic frameworks	47
Advances in the analysis of odorous substances derived from drinking water disinfection	47
Radiometric strategy to track nanopesticides: An important approach to understand the fate, mechanisms of action and toxicity	47
Recent advances of cellulose nanofiber-based materials in cell culture: From population to single-cell	47
Tracking indoor volatile organic compounds with online mass spectrometry	47
Editorial Board	47
Thermal shift assay for protein–ligand dissociation constant determination	47
Variable electric field and atomic percentage of doping on the displacement process of C20 molecules in a nanotube with molecular dynamics simulation	47
Recent advances in technologies toward the development of 2D materials-based electronic noses	47
Recent advances in exhaled breath sample preparation technologies for drug of abuse detection	46
Forensic drug screening by liquid chromatography hyphenated with high-resolution mass spectrometry (LC-HRMS)	46
Biosensing based on lossy mode resonances	46
Fluorescent probes based on bioorthogonal reactions: Construction strategies and applications	46
Emerging trends in green carbon dots coated with molecularly imprinted polymers for sensor platforms	46
Assessing the availability of trace metals including rare earth elements in deep ocean waters of the Clarion Clipperton Zone, NE Pacific: Application of an in situ DGT passive sampling method	46
Staining methodologies for microplastics screening	45
Green synthesis and characterization of carbon-based materials for sensitive detection of heavy metal ions	45
Plastic problem solved? Environmental implications of synthetic hydrophilic polymers across ecosystem boundaries	45
Carbon dots based fluorescence methods for the detections of pesticides and veterinary drugs: Response mechanism, selectivity improvement and application	45
Advances in nanomaterial-based microfluidic platforms for on-site detection of foodborne bacteria	45
An overview of analytical methods for enantiomeric determination of chiral pollutants in environmental samples and biota	45
Recent advances and applications of Bi2S3-based composites in photoelectrochemical sensors and biosensors	44
Biomarkers in the diagnosis of wounds infection: An analytical perspective	44
The application of coffee-ring effect in analytical chemistry	44
MOFs/COFs-based hybrids for agricultural sensors: Current state of art and beyond	44
Functionalized magnetic nanoparticles as powerful sorbents and stationary phases for the extraction and chromatographic applications	44
Enzyme and nanozyme biosensors based on MOFs for pesticide detection	44
Deep learning for near-infrared spectral data modelling: Hypes and benefits	44
Updated overview of QuEChERS applications in food, environmental and biological analysis (2020–2023)	44
Recent advances in microfluidic sensors for nutrients detection in water	44
Recent advances in responsive lanthanide-doped luminescence nanoprobes in the near-infrared-II window	43
A review on environmental isotope analysis of aquatic micropollutants: Recent advances, pitfalls and perspectives	43
Seeing the invisible: Preparative strategies to visualise elusive molecules using mass spectrometry imaging	43
Polymers modified porous silicon optical (bio)sensors	43
Microplastics, heavy metals, antibiotics, and antibiotic resistance genes in recirculating aquaculture systems	43
Reticular sensing materials with aggregation-induced emission characteristics	43
The role of oxylipins and their validation as biomarkers in the clinical context	43
Detection, characterization and imaging of micro- and nanoparticles in biotic tissues by laser-induced breakdown spectroscopy	43
Protein-mediated fluorescent probes for bioimaging and biosensing: From fundamentals to applications	43
Two-photon fluorescent probes for quantitative bio-imaging analysis in live tissues	43
Advances on constructing functional reticular materials for efficient determination of radionuclides	43
CRISPR techniques and potential for the detection and discrimination of SARS-CoV-2 variants of concern	43
Trends in bimetallic nanomaterials and methods for fourth-generation glucose sensors	42
Calibration methods in qualitative analysis	42
Human exposure to micro(nano)plastics: Health risks and analysis methods	42
Recent advances in data-mining techniques for measuring transformation products by high-resolution mass spectrometry	42
Enzyme-catalyzed molecular MR imaging of tumors	42
Micro/nanofluidic-electrochemical biosensors for in situ tumor cell analysis	42