Trends in Pharmacological Sciences

Papers
(The H4-Index of Trends in Pharmacological Sciences is 41. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Network pharmacology: curing causal mechanisms instead of treating symptoms444
Organ-on-a-Chip: A New Paradigm for Drug Development313
NLRP3 and pyroptosis blockers for treating inflammatory diseases299
Tryptophan Metabolism as a Pharmacological Target178
Drug Repurposing for Rare Diseases145
Metformin and Systemic Metabolism132
Physiological and pharmacological modulation of BAX116
Metastatic colorectal cancer: mechanisms and emerging therapeutics114
Iron metabolism: pathophysiology and pharmacology114
Neuroplasticity as a convergent mechanism of ketamine and classical psychedelics113
The Importance of Apparent pKa in the Development of Nanoparticles Encapsulating siRNA and mRNA112
Biased Allosteric Modulators: New Frontiers in GPCR Drug Discovery111
Machine Learning for Biologics: Opportunities for Protein Engineering, Developability, and Formulation104
Fruitful Neutralizing Antibody Pipeline Brings Hope To Defeat SARS-Cov-2104
Update and latest advances in antiretroviral therapy100
Critical Assessment of G Protein-Biased Agonism at the μ-Opioid Receptor100
Progranulin as a therapeutic target in neurodegenerative diseases87
Nrf2 for cardiac protection: pharmacological options against oxidative stress85
Peptide–drug conjugate-based novel molecular drug delivery system in cancer84
Targeting the Immune System for Ischemic Stroke84
AKAP Signaling Islands: Venues for Precision Pharmacology82
Advances and challenges in therapeutic targeting of NRF281
Mitochondrial quality control mechanisms as therapeutic targets in doxorubicin-induced cardiotoxicity80
Recent breakthroughs and future directions in drugging aquaporins70
Disrupting 3D printing of medicines with machine learning70
AI-powered therapeutic target discovery69
Emerging strategies for engineering Escherichia coli Nissle 1917-based therapeutics68
CSF and Blood Biomarkers in Neuroinflammatory and Neurodegenerative Diseases: Implications for Treatment61
Decoding pseudouridine: an emerging target for therapeutic development60
Computational and artificial intelligence-based methods for antibody development60
Circulating tumor cells in precision medicine: challenges and opportunities58
FOXO transcription factors as therapeutic targets in human diseases55
ER stress in obesity pathogenesis and management54
Affinity Hydrogels for Protein Delivery52
Overcoming the challenges of tissue delivery for oligonucleotide therapeutics52
Carbon Monoxide: from Poison to Clinical Trials49
3D cell cultures toward quantitative high-throughput drug screening48
Present and future of microglial pharmacology48
Structural perspective of class B1 GPCR signaling46
High-power screening (HPS) empowered by DNA-encoded libraries44
Biological Cells as Therapeutic Delivery Vehicles44
RNA Dysregulation: An Expanding Source of Cancer Immunotherapy Targets41
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