OOIR: Observatory of International Research

Papers

(The TQCC of Immunology Letters is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The impact of ageing on monocytes and macrophages	147
Plasticity of monocyte development and monocyte fates	49
Immune reactivity during COVID-19: Implications for treatment	45
STAT3 inhibition protects against neuroinflammation and BACE1 upregulation induced by systemic inflammation	42
A comprehensive review on miR-146a molecular mechanisms in a wide spectrum of immune and non-immune inflammatory diseases	41
Macrophage-derived exosomes in cancers: Biogenesis, functions and therapeutic applications	41
Mechanisms underpinning poor antibody responses to vaccines in ageing	41
Psychedelics as a novel approach to treating autoimmune conditions	39
Gene regulation of intracellular adhesion molecule-1 (ICAM-1): A molecule with multiple functions	38
Brain-resident regulatory T cells and their role in health and disease	37
Sulforaphane inhibits NLRP3 inflammasome activation in microglia through Nrf2-mediated miRNA alteration	33
CD4+ Cytotoxic T cells – Phenotype, Function and Transcriptional Networks Controlling Their Differentiation Pathways	32
Targeting the PI3K/Akt/mTOR pathway: A therapeutic strategy in COVID-19 patients	30
Low levels of pro-resolving lipid mediators lipoxin-A4, resolvin-D1 and resolvin-E1 in patients with rheumatoid arthritis	30
Immunomodulation by heavy metals as a contributing factor to inflammatory diseases and autoimmune reactions: Cadmium as an example	29
How NETosis could drive “Post-COVID-19 syndrome” among survivors	28
Gut microbiota, immunity and pain	27
New aspects in the regulation of human B cell functions by complement receptors CR1, CR2, CR3 and CR4	26
PD-1, CTLA-4, LAG-3, and TIGIT: The roles of immune checkpoint receptors on the regulation of human NK cell phenotype and functions	25
“Cytokine storm”, not only in COVID-19 patients. Mini-review	25
The MALAT1-H19/miR-19b-3p axis can be a fingerprint for diabetic neuropathy	25
LncRNA GAS5 suppresses CD4+ T cell activation by upregulating E4BP4 via inhibiting miR-92a-3p in systemic lupus erythematosus	24
IgD−CD27− double negative (DN) B cells: Origins and functions in health and disease	24
Immunotherapy in treatment of leishmaniasis	24
Determination of the transcriptional level of long non-coding RNA NEAT-1, downstream target microRNAs, and genes targeted by microRNAs in diabetic neuropathy patients	23

Interplays between inflammasomes and viruses, bacteria (pathogenic and probiotic), yeasts and parasites	23
Molecular pathways in sepsis-induced cardiomyocyte pyroptosis: Novel finding on long non-coding RNA ZFAS1/miR-138–5p/SESN2 axis	22
Inflammasomes in dendritic cells: Friend or foe?	21
Dynamic role of macrophage CX3CR1 expression in inflammatory bowel disease	21
Life and death of microglia: Mechanisms governing microglial states and fates	20
SARS-CoV-2 Spike protein enhances ACE2 expression via facilitating Interferon effects in bronchial epithelium	20
T follicular cells: The regulators of germinal center homeostasis	20
Immunodeficiency and thymoma in Good syndrome: Two sides of the same coin	19
The Impact of New Immunological Therapeutic Strategies on Recurrent Miscarriage and Recurrent Implantation Failure	19
Highly activated TRAIL+ CD56bright NK cells are associated with the liver damage in HBV-LC patients	19
The roles of STAT6 in regulating B cell fate, activation, and function	18
TLR ligand loaded exosome mediated immunotherapy of established mammary Tumor in mice	18
A tabulated summary of the evidence on humoral and cellular responses to the SARS-CoV-2 Omicron VOC, as well as vaccine efficacy against this variant.	18
Combinatmarion treatment with Lactobacillus acidophilus LA-1, vitamin B, and curcumin ameliorates the progression of osteoarthritis by inhibiting the pro-inflammatory mediators	18
Efficient roles of miR-146a in cellular and molecular mechanisms of neuroinflammatory disorders: An effectual review in neuroimmunology	18
The onco-immunological implications of Fusobacterium nucleatum in breast cancer	18
Effect of Perfluorooctanesulfonic acid (PFOS) on immune cell development and function in mice	17
Science fact vs science fiction: A ChatGPT immunological review experiment gone awry	17
Regulation of cellular immunity by activating transcription factor 4	17
Increased circulating PD-1hiCXCR5- peripheral helper T cells are associated with disease severity of active ulcerative colitis patients	17
Increased peripheral helper T cells type 17 subset correlates with the severity of psoriasis vulgaris	17
Pathogen infection routes and host innate immunity: Lessons from insects	17
Oral tolerance: an updated review	16
Dairy starters and fermented dairy products modulate gut mucosal immunity	16
A small molecule inhibitor of caspase-1 inhibits NLRP3 inflammasome activation and pyroptosis to alleviate gouty inflammation	16
HLA-C*17 in COVID-19 patients: Hints for associations with severe clinical outcome and cardiovascular risk	15
Heterogeneity of tissue resident memory T cells	15
Long-term omalizumab efficacy in allergic rhinitis	14
Complement System in Alcohol-Associated Liver Disease	14
The crosstalk between H. pylori virulence factors and the PD1:PD-L1 immune checkpoint inhibitors in progression to gastric cancer	14
MicroRNA-144-3p enhances LPS induced septic acute lung injury in mice through downregulating Caveolin-2	14
Abnormal membrane-bound and soluble programmed death ligand 2 (PD-L2) expression in systemic lupus erythematosus is associated with disease activity	13
A fresh look at a neglected regulatory lineage: CD8+Foxp3+ Regulatory T cells	13
AURKA facilitates the psoriasis-related inflammation by impeding autophagy-mediated AIM2 inflammasome suppression	13
Are the emerging SARS-COV-2 mutations friend or foe?	13
MiR-30a-3p ameliorates oxidative stress in rheumatoid arthritis synovial fibroblasts via activation of Nrf2-ARE signaling pathway	13
Pulmonary vascular improvement in severe COVID-19 patients treated with tocilizumab	13
Effects of exercise and anti-PD-1 on the tumour microenvironment	12
Neuroimmune communication in infection and pain: Friends or foes?	12
Progress in research into the role of abnormal glycosylation modification in tumor immunity	12
Neutrophils-typical atypical antigen presenting cells?	12
Overexpression of pigment epithelium-derived factor in breast cancer cell-derived exosomes induces M1 polarization in macrophages	12
B cells as target for immunotherapy in rheumatic diseases – current status	12
Inflammatory status might direct ILC and NK cells to IL-17 expressing ILC3 and NK subsets in Behcet's disease	12
Global histone modification analysis reveals hypoacetylated H3 and H4 histones in B Cells from systemic lupus erythematosus patients	12
Galectin-3 in T cell-mediated immunopathology and autoimmunity	11
Role, function and regulation of the thymocyte selection-associated high mobility group box protein in CD8+ T cell exhaustion	11
Junctional adhesion molecule-A on dendritic cells regulates Th1 differentiation	11
Emerging regulatory roles of opioid peptides, endogenous morphine, and opioid receptor subtypes in immunomodulatory processes: Metabolic, behavioral, and evolutionary perspectives	11
The Immune Dysregulation of Common Variable Immunodeficiency Disorders	11

Will a little change do you good? A putative role of polymorphisms in COVID-19	11
Immune cell-mediated opioid analgesia	11
Protective effect of Bacteroides fragilis LPS on Escherichia coli LPS-induced inflammatory changes in human monocytic cells and in a rheumatoid arthritis mouse model	10
Immune system aging and the aging-related diseases in the COVID-19 era	10
Inflammatory alveolar macrophage-derived microvesicles damage lung epithelial cells and induce lung injury	10
The mitochondria-targeting antioxidant MitoQ alleviated lipopolysaccharide/ d-galactosamine-induced acute liver injury in mice	10
Leptin promotes glycolytic metabolism to induce dendritic cells activation via STAT3-HK2 pathway	10
Improved engraftment of human peripheral blood mononuclear cells in NOG MHC double knockout mice generated using CRISPR/Cas9	10
IL-17A and IFN-γ are Up-regulated in CD4 and γδ T Cells in Active Behcet's Disease Patients	9
OVOL2 inhibits macrophage M2 polarization by regulating IL-10 transcription, and thus inhibits the tumor metastasis by modulating the tumor microenvironment	9
Asthma, obesity, and microbiota: A complex immunological interaction	9
Circ_100395 impedes malignancy and glycolysis in papillary thyroid cancer: Involvement of PI3K/AKT/mTOR signaling pathway	9
The neuro-immune axis in cancer: Relevance of the peripheral nervous system to the disease	9
Benralizumab reduces eosinophils and inflammatory markers in patients with severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps: A pilot real-life study.	9
The occurrence of lupus nephritis is regulated by USP7-mediated JMJD3 stabilization	9
Evaluation of an attenuated Listeria monocytogenes as a vaccine vector to control Helicobacter pylori infection	9
The intestinal microenvironment shapes macrophage and dendritic cell identity and function	9
BML-111, the lipoxin A4 agonist, modulates VEGF or CoCl2-induced migration, angiogenesis and permeability in tumor-derived endothelial cells	8
B19-VLPs as an effective delivery system for tumour antigens to induce humoral and cellular immune responses against triple negative breast cancer	8
Addressing the key issue: Antigen-specific targeting of B cells in autoimmune diseases	8
Methylmercury chloride exposure exacerbates existing neurobehavioral and immune dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism	8
Comparison of three different COVID-19 vaccine platforms (CoronaVac, BTN162b2, and Ad5-nCoV) in individuals with and without prior COVID-19: Reactogenicity and neutralizing antibodies	8
Emerging roles of non-coding RNAs in the metabolic reprogramming of tumor-associated macrophages	8
Hemin acts as CD36 ligand to activate down-stream signalling to disturb immune responses and cytokine secretion from macrophages	8
Insights into the role of complement system in the pathophysiology of endometriosis	7
Immune communication between the intestinal microbiota and the cardiovascular system	7
Aryl hydrocarbon receptor connects dysregulated immune cells to atherosclerosis	7
PD-1 Expression on CD8+CD28- T cells within inflammatory synovium is associated with Relapse: A cohort of Rheumatoid Arthritis	7
Targeted elimination of myeloid-derived suppressor cells via regulation of the STAT pathway alleviates tumor immunosuppression in neuroblastoma	7
GILT in tumor cells improves T cell-mediated anti-tumor immune surveillance	7
A brief history of epigenetics	7
Polarization of rheumatoid macrophages is regulated by the CDKN2B-AS1/ MIR497/TXNIP axis	7
CRISPR/Cas-based Human T cell Engineering: Basic Research and Clinical Application	7
Sepsis and multiple sclerosis: Causative links and outcomes	7
Distinct cell death markers identified in critical care patient survivors diagnosed with sepsis	7
CD36 as a double-edged sword in cancer	7
Metabolic regulation of follicular helper T cell differentiation in a mouse model of lupus	7
Preparation and in vitro activity of single chain antibodies against Alzheimer's disease	7
Immuno-hippo: Research progress of the hippo pathway in autoimmune disease	7