Immunology Letters

Papers
(The median citation count of Immunology Letters is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Baseline TGF-β correlates with protection after immunization with Plasmodium falciparum sporozoites in the controlled human malaria infection model51
Immunotherapy in treatment of leishmaniasis49
Strategies to reprogram anti-inflammatory macrophages towards pro-inflammatory macrophages to support cancer immunotherapies47
Downregulation of DNMT3a expression by RNAi and its effect on NF-κBs expression of thymic epithelial cells46
Dengue virus induces interferon-β by activating RNA sensing pathways in megakaryocytes46
BTN2A2-Ig protein inhibits the differentiation of pathogenic Th17 cells and attenuates EAE in mice43
Expression of epidermal growth factor receptor (EGFR) in systemic sclerosis patients (SSc) and gastro-oesophageal reflux disease (GORD)36
Obituary for Prof. Reinhold E Schmidt, MD (1951 – 2022)34
Autophagy and LC3-associated phagocytosis contribute negatively to the killing capability of THP-1-derived macrophages against Candida albicans at the mid-stage33
Targeting plasma cells in systemic autoimmune rheumatic diseases – Promises and pitfalls31
YAP1 induces marrow derived suppressor cell recruitment in Chlamydia trachomatis infection29
Platelet dropping, bleeding and new treatment requirements in ITP patients after inactivated COVID-19 vaccination29
Use of recombinant S1 protein with hFc for analysis of SARS-CoV-2 adsorption and evaluation of drugs that inhibit entry into VERO E6 cells28
Corrigendum to ’ Aged AβPPswe/PS1ΔE9 mice as a useful animal model for studying the link between immunological senescence and diseases’[Immunol Lett. 2024 Feb 12:266:106842]27
Combining local cryoablation with PD-L1 blockade synergistically eradicates established murine lung cancer by modulating mitochondrial in PD-1+CD8+ T cell26
Serum interleukin-38 and -41 levels as candidate biomarkers in male infertility26
Isolation of CD35+ follicular dendritic cells and its role in the differentiation from B cells to IgA+GL7+ cells24
Editorial Board24
Could anti-ACE2 antibodies alter the results of SARS-CoV-2 Ab neutralization assays?24
Functions of NK and iNKT cells in pediatric and adult CVID, ataxia telangiectasia and agammaglobulinemia patients23
Immunoregulatory properties of melatonin in the humoral immune system: A narrative review23
A fresh look at a neglected regulatory lineage: CD8+Foxp3+ Regulatory T cells23
Filarial infections compromise influenza vaccination efficacy: Lessons from the mouse23
Alterations of B-Cell subsets in Peripheral Blood from Adult Patients with Idiopathic Membranous Nephropathy22
Could there be a relationship between type III hypersensitivity reactions and graft rejections?22
Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner22
A blinded multicenter investigation: Accentuated NK lymphocyte CD335 (NKp46) expression predicts reproductive failures after IVF.21
Benzo[a]pyrene exposure causes exonal switch resulting in reduced surface CD5 expression in an AHR-dependent manner21
Pathophysiology of cutaneous T-cell lymphomas: Perspective from a French referral centre21
Thymocyte migration and emigration20
Compartmentalization of gut immune responses: Mucosal niches and lymph node peculiarities19
Untangling associations between immunoglobulin genotypes, repertoires and function19
B cells as target for immunotherapy in rheumatic diseases – current status18
Inflammatory status might direct ILC and NK cells to IL-17 expressing ILC3 and NK subsets in Behcet's disease18
Obituary for Prof. Miodrag L. Lukic, MD, PhD (1941 – 2023)18
Overlapping GAD65-associated autoimmune neurological syndromes and type 1 diabetes18
Acute effects of TLR3 agonist Poly(I:C) on bone marrow hematopoietic progenitor cells in mice16
Construction of CAR-T cells targeting TM4SF1 and its anti-tumor capacity in ovarian cancer16
Neuro-immune-metabolism: The tripod system of homeostasis16
Human dendritic cell differentiation in hematopoietic stem cell-transplanted NOG hFLT3L Tg/mFlt3 KO humanized mice16
Unfolding the symbiosis of AID, chromatin remodelers, and epigenetics–The ACE phenomenon of antibody diversity16
The miR-142 miRNAs: Shaping the naïve immune system15
Corrigendum to ‘Eomesodermin promotes interaction of RelA and NFATc2 with the Ifng promoter and multiple conserved noncoding sequences across the Ifng locus in mouse lymphoma BW5147 cells’[Immunology 14
Inhibition of glutaminase 1 reduces M1 macrophage polarization to protect against monocrotaline-induced pulmonary arterial hypertension14
Fingolimod, an antagonist of sphingosine 1-phosphate, ameliorates Sjögren's syndrome by reducing the number of STAT3–induced germinal center B cells and increasing the number of Breg cells14
Immune cell profiles and patient clustering in complex cases of interstitial lung disease14
CD4+ Cytotoxic T cells – Phenotype, Function and Transcriptional Networks Controlling Their Differentiation Pathways14
A tabulated summary of the evidence on humoral and cellular responses to the SARS-CoV-2 Omicron VOC, as well as vaccine efficacy against this variant.13
A novel form of immunotherapy using antigen peptides conjugated on PD-L1 antibody13
Human toll-like receptor 8 (TLR8) in NK cells: Implication for cancer immunotherapy12
Myocarditis development after COVID-19 vaccination in an immunodeficient case12
Rescuing pathogen-specific memory B-cell from PBMC of prior Zika virus-infected individuals12
Mechanism of M2 macrophages modulating astrocyte polarization through the TGF-β/PI3K/Akt pathway12
Editorial Board11
IL-38 in Behçet's disease: Gene expression in bronchoalveolar lavage from patients having pulmonary involvement11
The evaluation of PD-1 and Tim-3 expression besides their related miRNAs in PBMCs of women with recurrent pregnancy loss11
Mucosal associated invariant T cells: Powerhouses of the lung11
Editorial Board11
Hemin acts as CD36 ligand to activate down-stream signalling to disturb immune responses and cytokine secretion from macrophages11
Human T cells show plasticity for direct recognition of xenogeneic dendritic cells11
Modulation of oxidized low-density lipoprotein-affected macrophage efferocytosis by mitochondrial calcium uniporter in a murine model10
Corrigendum to “Identification and suppression of epidermal growth factor receptor variant III signaling in fibroblast-like synoviocytes from aggressive rheumatoid arthritis by the mimotope” [Immunolo9
Antibodies to expanded virus antigen panels show elevated diagnostic sensitivities in multiple sclerosis and optic neuritis9
Global histone modification analysis reveals hypoacetylated H3 and H4 histones in B Cells from systemic lupus erythematosus patients9
Endoplasmic reticulum stress response in immune cells contributes to experimental autoimmune encephalomyelitis pathogenesis in rats9
Relevance of autoantibody profile with HLA-DRB1 and -DQB1 alleles in a group of Iranian systemic lupus erythematosus patients9
Neutralization of IL-6 inhibits formation of autoreactive TH17 cells but does not prevent loss of renal function in experimental autoimmune glomerulonephritis9
TIPE-2 ameliorates inflammatory bowel disease in mice via inhibiting STAT3 and NF-kB activation9
Corrigendum to “The role of IgA in gastrointestinal helminthiasis: A systematic review” [Immunology Letters (2022) 12-22, Volume: 249]9
Conjugation of human serum albumin and flucloxacillin provokes specific immune response in HLA-B*57:01 transgenic mice9
Inflammatory response-related genes predict prognosis in patients with HNSCC9
Editorial Board8
Rheumatoid arthritis autologous synovial fluid affects the plasticity and function of peripheral and induced T regulatory cells in vitro8
Immune communication between the intestinal microbiota and the cardiovascular system8
The modulatory effect of crotoxin and its phospholipase A2 subunit from Crotalus durissus terrificus venom on dendritic cells interferes with the generation of effector CD4+ T lymphocytes8
Prognostic value of CD163+ macrophages in solid tumor malignancies: A scoping review8
Metformin inhibits the pathogenic functions of AChR-specific B and Th17 cells by targeting miR-146a8
Single-cell communication patterns and their intracellular information flow in synovial fibroblastic osteoarthritis and rheumatoid arthritis8
IgD−CD27− double negative (DN) B cells: Origins and functions in health and disease8
Recombinant MUC1-MBP fusion protein combined with CpG2006 vaccine induces antigen-specific CTL responses through cDC1-mediated cross-priming mainly regulated by type I IFN signaling in mice8
Different effectiveness of fungal pathogen-associated molecular patterns (PAMPs) in activating rat peritoneal mast cells8
Increased circulating PD-1hiCXCR5- peripheral helper T cells are associated with disease severity of active ulcerative colitis patients8
Benralizumab reduces eosinophils and inflammatory markers in patients with severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps: A pilot real-life study.8
Autoantibody mediated deficiency of IL-36-receptor antagonist in a subset of patients with psoriasis and psoriatic arthritis7
Potential utility of calculated globulin as a screening tool for antibody deficiency in children7
In virto priming of the STING signaling pathway enhances the maturation and activation of dendritic cells induced by hepatitis B vaccine7
Will a little change do you good? A putative role of polymorphisms in COVID-197
Dendritic cells in energy balance regulation7
Intestinal epithelial vitamin D receptor defense against inflammatory bowel disease via regulating microfold cells7
Pitfalls in establishing mouse model of female infertility by immunization with human centromere protein7
Interstitial lung disease progression in patients with anti-aminoacyl transfer-RNA-synthetase autoantibodies is characterized by higher levels of sCD1637
Annickia polycarpa extract attenuates inflammation, neutrophil recruitment, and colon damage during colitis7
The role of mannose-binding lectin (MBL) in diabetic retinopathy: A scoping review6
Methylmercury chloride exposure exacerbates existing neurobehavioral and immune dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism6
Cellular mechanisms underlying the impairment of macrophage efferocytosis6
Epstein–Barr virus and genetic risk variants as determinants of T-bet+ B cell-driven autoimmune diseases6
B7-H3 blockade decreases macrophage inflammatory response and alleviates clinical symptoms of arthritis6
The phagocytosis dysfunction in lupus nephritis is related to monocyte/macrophage CPT1a6
McH-lpr/lpr-RA1 mice: A novel spontaneous mouse model of autoimmune sialadenitis6
Membrane prohibitin forms a dynamic complex with p56lck to regulate T cell receptor signaling6
3′UTR-HLA-G polymorphisms and circulating sHLA-G are associated with breast cancer: Evidence from a meta-analysis6
Editorial Board6
A message from the new Editor-in-Chief Luis Graca6
Neonatal Streptococcus Pneumoniae pneumonia induces airway SMMHC expression through HMGB1/TLR4/ERK6
DCAF1 inhibits the NF-κB pathway by targeting p656
Naturally occurring hypothermia promotes survival in severe anaphylaxis6
The importance of type I interferon in orchestrating the cytotoxic T-cell response to cancer6
Tumor-associated NK cells facilitate tumor growth via NKp46 in immunocompetent murine hepatocellular carcinoma5
Fighting the enemy within: Systemic immune defense against mucosal Salmonella infection5
IL-17A and IFN-γ are Up-regulated in CD4 and γδ T Cells in Active Behcet's Disease Patients5
Molecular pathways in sepsis-induced cardiomyocyte pyroptosis: Novel finding on long non-coding RNA ZFAS1/miR-138–5p/SESN2 axis5
Could tolerance to DNA be broken in the gut in systemic lupus erythematosus?5
Sex-specific remodeling of T-cell compartment with aging: Implications for rat susceptibility to central nervous system autoimmune diseases5
Human and mouse early B cell development: So similar but so different5
Dextran sulfate sodium-induced gut microbiota dysbiosis aggravates liver injury in mice with S100-induced autoimmune hepatitis5
Reduced TRIM expression correlates with anomalous CD4 T cell activation in systemic lupus Erythematosus and its clinical diagnostic potential5
Eosinophils are sparse in homeostatic rectal tissue which impedes studying resident eosinophils5
Protective effect of Bacteroides fragilis LPS on Escherichia coli LPS-induced inflammatory changes in human monocytic cells and in a rheumatoid arthritis mouse model5
Immune checkpoint molecules in solid organ transplantation: A promising way to prevent rejection5
The Th1/Th2 paradigm: A misrepresentation of helper T cell plasticity5
Science fact vs science fiction: A ChatGPT immunological review experiment gone awry5
Dual drug nanoparticle synergistically induced apoptosis, suppressed inflammation, and protected autophagic response in rheumatoid arthritis fibroblast-like synoviocytes5
Alendronate modulates cytokine responses in healthy young individuals after BCG vaccination5
Sequence similarity suggests molecular mimicry-induced cardiovascular symptoms in multisystem inflammatory syndrome in children (MIS-C)5
Insights into the relationship between persistent antibody secretion and metabolic programming – A question for single-cell analysis5
In adult X-CGD patients, regulatory T cells are expanded while activated T cells display a NOX2-independent ROS increase5
Longitudinal analysis at pre- and post-flare of T peripheral helper and T follicular helper subsets in patients with systemic lupus erythematosus5
Rho-kinase inhibitors to deplete age-associated B cells in systemic autoimmunity5
Platelet-Derived Microvesicles Modulate Cytokine and Lipid Mediator Profiles in THP-1 Monocytes and Macrophages4
Brain-resident regulatory T cells and their role in health and disease4
Immunomodulation by heavy metals as a contributing factor to inflammatory diseases and autoimmune reactions: Cadmium as an example4
A small molecule inhibitor of caspase-1 inhibits NLRP3 inflammasome activation and pyroptosis to alleviate gouty inflammation4
Enhanced immunoprotection against Acinetobacter baumannii infection: Synergistic effects of Bap and BauA in a murine model4
IL-1β blockade prevents cell death and mucosal damage of the small intestine in a model of sterile inflammation4
Harnessing immunomodulatory mechanisms of Trichinella spiralis to design novel nanomedical approaches for restoring self-tolerance in autoimmunity4
T cell landscape in the microenvironment of human solid tumors4
Corrigendum to “Metformin inhibits the pathogenic functions of AChR-specifc B and Th17 cells by targeting miR-146a” [Immunology Letters 250 (2022) 29–40 on Sep 13, 2022/ Manuscript ID: IMLET-D-22-00154
Editorial Board4
A newly developed PLD1 inhibitor ameliorates rheumatoid arthritis by regulating pathogenic T and B cells and inhibiting osteoclast differentiation4
Acute and prolonged effects of interleukin-33 on cytokines in human cord blood-derived mast cells4
Heterogeneity of tissue resident memory T cells4
Immunogenic profiling of Mycobacterium tuberculosis DosR protein Rv0569 reveals its ability to switch on Th1 based immunity4
Synergistic neuroprotective effects of Fingolimod and mesenchymal stem cells (MSC) in experimental autoimmune encephalomyelitis4
COVID-19 acute respiratory distress syndrome promotes a specific alternative macrophage polarization4
OVOL2 inhibits macrophage M2 polarization by regulating IL-10 transcription, and thus inhibits the tumor metastasis by modulating the tumor microenvironment4
Ursolic acid attenuates pseudo-allergic reactions via reducing MRGPRX2-mediated mast cell degranulation4
Single Cell Multiomic Approaches to Disentangle T Cell Heterogeneity4
Gene therapy strategies for RAG1 deficiency: Challenges and breakthroughs4
Silencing TRIM8 alleviates allergic asthma and suppressing Th2 differentiation through inhibiting NF-κB/NLRP3 signaling pathway4
Corrigendum to “Matrine downregulates IL-33/ST2 expression in the central nervous system of rats with experimental autoimmune encephalomyelitis” [Immunol Lett. 178(2016) 97–104]4
The disturbance and clinical significance of B cell and circulating follicular helper T cell subsets in children with primary nephrotic syndrome4
The intestinal microenvironment shapes macrophage and dendritic cell identity and function4
Mettl14 sustains FOXP3 expression to promote the differentiation and functions of induced-regulatory T cells via the mTOR signaling pathway4
A new experimental model to study shrimp allergy4
New monogenic autoinflammatory diseases: 2021 year in review4
The oncolytic virus VT09X optimizes immune checkpoint therapy in low immunogenic melanoma4
Interleukin-40 is a promising biomarker associated with type 2 diabetes mellitus risk3
Targeted elimination of myeloid-derived suppressor cells via regulation of the STAT pathway alleviates tumor immunosuppression in neuroblastoma3
Final step of B-cell differentiation into plasmablasts; the right time to activate plasma cell PIM2 kinase3
The engineered agonistic anti-CD40 antibody potentiates the antitumor effects of β-glucan by resetting TAMs3
B19-VLPs as an effective delivery system for tumour antigens to induce humoral and cellular immune responses against triple negative breast cancer3
Post-transcriptional control of T-cell development in the thymus3
Pentavalent outer membrane vesicles immunized mice sera confers passive protection against five prevalent pathotypes of diarrhoeagenic Escherichia coli in neonatal mice3
CD36 as a double-edged sword in cancer3
HLA-C*17 in COVID-19 patients: Hints for associations with severe clinical outcome and cardiovascular risk3
Characterization of CD31 expression in CD4+ and CD8+T cell subpopulations in chronic untreated HIV infection3
NLRC3 affects the development of psoriasis by modulating the NF-κB signaling pathway mediated inflammatory response through its interaction with TRAF63
Musculin does not modulate the disease course of Experimental Autoimmune Encephalomyelitis and DSS colitis3
Brain inflammation in experimental autoimmune encephalomyelitis induced in Dark Agouti rats with spinal cord homogenate3
PD-1, CTLA-4, LAG-3, and TIGIT: The roles of immune checkpoint receptors on the regulation of human NK cell phenotype and functions3
Adenine is an anti-inflammatory metabolite found to be more abundant in M-CSF over GM-CSF-differentiated human macrophages3
Corrigendum to “Interleukin-40 is a promising biomarker associated with type 2 diabetes mellitus risk” [Immunology Letters 254 (2023) 1–5]3
Roles of leptin on the key effector cells of rheumatoid arthritis3
Dermcidin-derived polypeptides: DCD(86-103) induced inflammatory reaction in the skin by activation of mast cells via ST23
Conventional dendritic cells 2, the targeted antigen-presenting-cell, induces enhanced type 1 immune responses in mice immunized with CVC1302 in oil formulation3
PLC-IP3-ORAI pathway participates in the activation of the MRGPRB2 receptor in mouse peritoneal mast cells3
X-ray irradiation reduces ATP-dependent activation of NLRP3 inflammasome by inhibiting TWIK2 activity in macrophages3
CRISPR/Cas-based Human T cell Engineering: Basic Research and Clinical Application3
Deletion of the 3′RR cis-enhancer IgH element affects DNA repair junctions during B-cell class switch recombination.3
Oral tolerance: an updated review3
Differential structure and immunomodulatory functions of lipophosphoglycan between Leishmania spp3
Dysregulated serum lipid profile is associated with inflammation and disease activity in primary Sjögren's syndrome: a retrospective study in China3
The frequencies of lymphocyte subsets on “day 30″ correlate with the clinical outcome of pediatric hematopoietic stem cell transplantation3
Dysregulated Th17/Treg cell axis is correlated with local and systemic immune response in human intermediate uveitis3
The roles of STAT6 in regulating B cell fate, activation, and function3
TLR3 and TLR7/8 agonists improve immunization outcome in nicotine exposed mice through different mechanisms3
Building the synapse engine to drive B lymphocyte function3
Impact of genetic variation on the molecular mimicry between Anoctamin-2 and Epstein-Barr virus nuclear antigen 1 in Multiple Sclerosis3
NK cell receptors in anti-tumor and healthy tissue protection: Mechanisms and therapeutic advances2
Effects of CRAMP on the gut-brain axis in experimental sepsis2
The imbalance of circulating monocyte subgroups with a higher proportion of the CD14+CD16+CD163+ phenotype in patients with preeclampsia2
Activation of cannabinoid receptors 2 alleviates myocardial damage in cecal ligation and puncture-induced sepsis by inhibiting pyroptosis2
Weller et al., T-independent responses to polysaccharides in humans mobilize marginal zone B cells pre-diversified against gut bacterial antigens2
The role of IgA in gastrointestinal helminthiasis: A systematic review2
The effect of abnormal lipid metabolism on immunosenescence of the colonic lamina propria in mice of different ages2
Dairy starters and fermented dairy products modulate gut mucosal immunity2
Single-cell sequencing has revealed a more complex array of thymic epithelial cells2
Targeting the PI3K/Akt/mTOR pathway: A therapeutic strategy in COVID-19 patients2
Impairment of effector molecules response in diabetes induces susceptibility to Leishmania amazonensis infection2
The influence of physical activity level and cytomegalovirus serostatus on the cytokine levels of young individuals2
Metabolic regulation of follicular helper T cell differentiation in a mouse model of lupus2
Could we use PD-1 and PD-L1 expression on lymphocytes and monocytes as predictive markers for prognosis of acute biliary pancreatitis?2
Reduced EO771-induced tumour growth and increased overall-survival of mice ablated for immune cell-specific catalytic subunit Cβ2 of protein kinase A2
The MALAT1-H19/miR-19b-3p axis can be a fingerprint for diabetic neuropathy2
Phosphatidylserine promotes immunotherapy for airway allergy2
Aloe-emodin relieves allergic contact dermatitis pruritus by inhibiting mast cell degranulation2
Mechanisms of histamine release from mast cells beyond the high affinity IgE receptor in severe chronic spontaneous urticaria2
Recent preclinical study offers a promising clue: Role of regulatory T cells as biomarkers in migraine2
Does atopic dermatitis increase the risk of allergic contact dermatitis?2
Long-term monocyte activation after coronary artery bypass grafting: An exploratory prospective observational study2
A novel antibody against the furin cleavage site of SARS-CoV-2 spike protein: Effects on proteolytic cleavage and ACE2 binding2
Triptolide alleviates acute gouty arthritis caused by monosodium urate crystals by modulating macrophage polarization and neutrophil activity2
Elevated circulating CD19+CD24hiCD38hi B cells display pro-inflammatory phenotype in idiopathic membranous nephropathy2
CD73 in glioblastoma: Where are we now and what are the future directions?2
Thymic atrophy induced by Plasmodium berghei ANKA and Plasmodium yoelii 17XL infection2
Editorial Board2
Neutrophils-typical atypical antigen presenting cells?2
Emerging roles for RNA-binding proteins in T lymphocytes2
Identification of S100A9 as a target for diagnosis and treatment of Crohn’s Disease after Vedolizumab treatment failure2
Elevated CD38 expression characterizes impaired CD8+ T cell immune response in metastatic pleural effusions2
Identification and characterization of circulating and adipose tissue infiltrated CD20+ T cells from subjects with obesity that undergo bariatric surgery2
Adaptive T cell tuning in immune regulation and immunotherapy of autoimmune diseases✰2
Expression of concern: “Interleukin-40 is a promising biomarker associated with type 2 diabetes mellitus risk” [Immunology Letters 254 (2023) 1–5]2
Monocyte chemokine receptors as therapeutic targets in cardiovascular diseases2
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