Immunology Letters

Papers
(The median citation count of Immunology Letters is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Taurohyodeoxycholic acid ameliorates inflammatory response in a murine model of ovalbumin (OVA)-induced allergic asthma77
BTN2A2-Ig protein inhibits the differentiation of pathogenic Th17 cells and attenuates EAE in mice75
Baseline TGF-β correlates with protection after immunization with Plasmodium falciparum sporozoites in the controlled human malaria infection model71
Editorial Board38
Virus-specific antibody responses in severe acute respiratory syndrome coronavirus 2-infected and vaccinated individuals35
Strategies to reprogram anti-inflammatory macrophages towards pro-inflammatory macrophages to support cancer immunotherapies31
Autoantibodies and therapeutic antibodies against complement factor H29
Letter to the editor: "Importance of BCG vaccination at birth in pediatric patients with chronic granulomatous disease after hematopoietic stem cell transplantation in developing countries"29
The vimentin-targeting monoclonal antibody hzVSF-V13 reduces TH17 cell numbers and osteoclastogenesis to attenuate rheumatoid arthritis progression28
Autophagy and LC3-associated phagocytosis contribute negatively to the killing capability of THP-1-derived macrophages against Candida albicans at the mid-stage27
Platelet dropping, bleeding and new treatment requirements in ITP patients after inactivated COVID-19 vaccination27
Use of recombinant S1 protein with hFc for analysis of SARS-CoV-2 adsorption and evaluation of drugs that inhibit entry into VERO E6 cells26
Combining local cryoablation with PD-L1 blockade synergistically eradicates established murine lung cancer by modulating mitochondrial in PD-1+CD8+ T cell26
B cells in inflammatory bowel disease25
Serum interleukin-38 and -41 levels as candidate biomarkers in male infertility24
NETs activate AIM2 to mediate synovial fibroblast pyroptosis and promote acute gouty arthritis development22
Corrigendum to ’ Aged AβPPswe/PS1ΔE9 mice as a useful animal model for studying the link between immunological senescence and diseases’[Immunol Lett. 2024 Feb 12:266:106842]21
Editorial Board21
Expression of epidermal growth factor receptor (EGFR) in systemic sclerosis patients (SSc) and gastro-oesophageal reflux disease (GORD)21
Targeting plasma cells in systemic autoimmune rheumatic diseases – Promises and pitfalls21
Filarial infections compromise influenza vaccination efficacy: Lessons from the mouse20
Benzo[a]pyrene exposure causes exonal switch resulting in reduced surface CD5 expression in an AHR-dependent manner19
Editorial Board18
Immunoregulatory properties of melatonin in the humoral immune system: A narrative review18
Could there be a relationship between type III hypersensitivity reactions and graft rejections?18
Increased expression of membrane-bound TGF-β1, GITR, and GITR ligand in patients with autoimmune thyroid disease17
Could anti-ACE2 antibodies alter the results of SARS-CoV-2 Ab neutralization assays?17
Alterations of B-Cell subsets in Peripheral Blood from Adult Patients with Idiopathic Membranous Nephropathy17
Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner17
Untangling associations between immunoglobulin genotypes, repertoires and function16
Post hoc analysis: 6 Months immunogenicity after third dose of BNT162b2 vs JNJ-78,436,735 after two doses of BNT162b2 vaccine in solid organ transplant recipients16
A fresh look at a neglected regulatory lineage: CD8+Foxp3+ Regulatory T cells16
FOXN1 immunodeficiency detected by TREC-based newborn screening - A challenge of management?15
Double positive IL-17A+IFN-γ+CCR6+ ILCs contribute towards the immunopathology of lepromatous leprosy15
A blinded multicenter investigation: Accentuated NK lymphocyte CD335 (NKp46) expression predicts reproductive failures after IVF.15
Interaction between IL-23/Th17 immune inflammatory axis and intestinal flora in gastric mucosal atrophy caused by Helicobacter pylori infection in the elderly15
Compartmentalization of gut immune responses: Mucosal niches and lymph node peculiarities15
Thymocyte migration and emigration15
Pathophysiology of cutaneous T-cell lymphomas: Perspective from a French referral centre14
Human keratinocytes exposed to a clinical strain of Leishmania tropica can result in parasite internalization14
Molecular requirements of pathogenic Th2 cell differentiation in allergic airway disease14
Unfolding the symbiosis of AID, chromatin remodelers, and epigenetics–The ACE phenomenon of antibody diversity13
Human dendritic cell differentiation in hematopoietic stem cell-transplanted NOG hFLT3L Tg/mFlt3 KO humanized mice13
Previous administration of recombinant or wild type Lactococcus lactis NCDO2118 prevented severe mucositis in mice13
Obituary for Prof. Miodrag L. Lukic, MD, PhD (1941 – 2023)13
Escherichia coli J5-derived OMVs with hypoendotoxic LPS: Potential boosters of T-cell immunity and IL-17 production for enhanced vaccine efficacy13
The miR-142 miRNAs: Shaping the naïve immune system12
Construction of CAR-T cells targeting TM4SF1 and its anti-tumor capacity in ovarian cancer12
Dendritic Cells: key controllers of lymphoid tissue organization12
Impact of afatinib on intestinal and salivary IgA: Immune response alterations linked to gastrointestinal side effects12
Inhibition of glutaminase 1 reduces M1 macrophage polarization to protect against monocrotaline-induced pulmonary arterial hypertension12
Acute effects of TLR3 agonist Poly(I:C) on bone marrow hematopoietic progenitor cells in mice11
Human toll-like receptor 8 (TLR8) in NK cells: Implication for cancer immunotherapy11
Immune cell profiles and patient clustering in complex cases of interstitial lung disease11
Anti-inflammatory potential of pre-formulated Aloe vera in mitigating allergen-induced airway responses in mice11
CD4+ Cytotoxic T cells – Phenotype, Function and Transcriptional Networks Controlling Their Differentiation Pathways11
Myocarditis development after COVID-19 vaccination in an immunodeficient case11
Characteristics and specific differential gene analysis of the TCR immune repertoire in secondary adult HLH lymphocytes10
Mechanism of M2 macrophages modulating astrocyte polarization through the TGF-β/PI3K/Akt pathway10
The CSF transcriptome in adults with pneumococcal meningitis reveals compartmentalised host inflammatory responses associated with mortality10
Immune cells and functions in patients with restless legs syndrome10
Editorial Board10
Rescuing pathogen-specific memory B-cell from PBMC of prior Zika virus-infected individuals10
Fingolimod, an antagonist of sphingosine 1-phosphate, ameliorates Sjögren's syndrome by reducing the number of STAT3–induced germinal center B cells and increasing the number of Breg cells10
Editorial Board10
Substrate availability and citrate alter TCA cycle metabolism and SLC13A3 in macrophage immune responses10
TIPE-2 ameliorates inflammatory bowel disease in mice via inhibiting STAT3 and NF-kB activation9
Inflammatory response-related genes predict prognosis in patients with HNSCC9
Mucosal associated invariant T cells: Powerhouses of the lung9
Endoplasmic reticulum stress response in immune cells contributes to experimental autoimmune encephalomyelitis pathogenesis in rats9
Human T cells show plasticity for direct recognition of xenogeneic dendritic cells9
IL-38 in Behçet's disease: Gene expression in bronchoalveolar lavage from patients having pulmonary involvement9
Electrostatic potential is the dominant force in antigenic selection of naïve T-cells and B-cells for activation and maturation9
CD4 and CD8 T-cell lymphocytes from penile squamous cell carcinoma tumors are more differentiated with higher PD-1 expression compared to lymphocytes in peripheral circulation9
Modulation of oxidized low-density lipoprotein-affected macrophage efferocytosis by mitochondrial calcium uniporter in a murine model9
Corrigendum to “The role of IgA in gastrointestinal helminthiasis: A systematic review” [Immunology Letters (2022) 12-22, Volume: 249]8
Conjugation of human serum albumin and flucloxacillin provokes specific immune response in HLA-B*57:01 transgenic mice8
CD4+ T-cell help delivery to monocyte-derived dendritic cells promotes effector differentiation of helper and cytotoxic T cells8
Corrigendum to “Identification and suppression of epidermal growth factor receptor variant III signaling in fibroblast-like synoviocytes from aggressive rheumatoid arthritis by the mimotope” [Immunolo8
The evaluation of PD-1 and Tim-3 expression besides their related miRNAs in PBMCs of women with recurrent pregnancy loss8
Comparison of IgG antibody levels, avidity, and subclass distribution against pertussis toxin in children and adolescents after four-dose primary whole-cell (DTwP) or acellular (DTaP) vaccination, eac8
Quercetin improves macrophage immune regulatory functions to alleviate airway Th2 polarization7
IgD−CD27− double negative (DN) B cells: Origins and functions in health and disease7
Immunometabolites and cancer: the role of 2-hydroxyglutarate, succinate, fumarate and itaconate in tumour development and anti-tumour immunity7
Prognostic value of CD163+ macrophages in solid tumor malignancies: A scoping review7
Metformin inhibits the pathogenic functions of AChR-specific B and Th17 cells by targeting miR-146a7
Environmental determinants of immune tolerance in asthma and allergy7
Single-cell communication patterns and their intracellular information flow in synovial fibroblastic osteoarthritis and rheumatoid arthritis7
Different effectiveness of fungal pathogen-associated molecular patterns (PAMPs) in activating rat peritoneal mast cells7
Immune communication between the intestinal microbiota and the cardiovascular system7
Rheumatoid arthritis autologous synovial fluid affects the plasticity and function of peripheral and induced T regulatory cells in vitro7
Antibodies to expanded virus antigen panels show elevated diagnostic sensitivities in multiple sclerosis and optic neuritis7
IL-21 promotes plasmablast differentiation independently of proliferation in vitro7
Editorial Board7
Benralizumab reduces eosinophils and inflammatory markers in patients with severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps: A pilot real-life study.7
DCAF1 inhibits the NF-κB pathway by targeting p656
Immunological features driving distinct repigmentation patterns in patients with stable vitiligo submitted to the autologous keratinocyte/melanocyte transplantation6
3′UTR-HLA-G polymorphisms and circulating sHLA-G are associated with breast cancer: Evidence from a meta-analysis6
Intestinal epithelial vitamin D receptor defense against inflammatory bowel disease via regulating microfold cells6
Potential utility of calculated globulin as a screening tool for antibody deficiency in children6
Space immunology: Unraveling immune system dysregulation in long-duration spaceflight and its implications for earth-based autoimmune and inflammatory diseases6
Autoantibody mediated deficiency of IL-36-receptor antagonist in a subset of patients with psoriasis and psoriatic arthritis6
Editorial Board6
The role of mannose-binding lectin (MBL) in diabetic retinopathy: A scoping review6
Sepsis as a complex syndrome: Are combined biomarkers the future of diagnosis and prognosis? Clinical perspective6
Maternal immunoglobulins differentially bind a diverse bacterial community in human colostrum and the stool of breastfed neonates6
Epstein–Barr virus and genetic risk variants as determinants of T-bet+ B cell-driven autoimmune diseases6
TNFAIP8 targets ATG3 to regulate autophagy and participate in the molecular mechanism of ankylosing spondylitis6
Interstitial lung disease progression in patients with anti-aminoacyl transfer-RNA-synthetase autoantibodies is characterized by higher levels of sCD1636
Compartment-specific activation of kinin B1 and B2 receptors drives the production of vasoactive and inflammatory mediators during SARS-CoV-2 infection6
The phagocytosis dysfunction in lupus nephritis is related to monocyte/macrophage CPT1a6
Innate lymphoid cells: Dual roles and therapeutic opportunities in breast cancer6
Profiling of circulating T follicular helper and T peripheral helper cell subsets in patients with primary biliary cholangitis6
Remdesivir alleviates joint damage in collagen-induced arthritis and inhibits inflammatory cell death of RA synovial fibroblasts6
Annickia polycarpa extract attenuates inflammation, neutrophil recruitment, and colon damage during colitis6
When immunity multitasks: type 2 pathways power thymus regeneration6
The importance of type I interferon in orchestrating the cytotoxic T-cell response to cancer6
Dendritic cells in energy balance regulation6
Systemic and cerebrospinal fluid immune mediators coordinate a dichotomic microenvironment in parturients with acute or convalescent phases of COVID-196
In virto priming of the STING signaling pathway enhances the maturation and activation of dendritic cells induced by hepatitis B vaccine6
B cells are major players in cancer immunity6
Evaluation of the diagnostic and prognostic role of TSPAN32 in B-cell acute lymphoblastic leukemia6
Dual drug nanoparticle synergistically induced apoptosis, suppressed inflammation, and protected autophagic response in rheumatoid arthritis fibroblast-like synoviocytes5
Sequence similarity suggests molecular mimicry-induced cardiovascular symptoms in multisystem inflammatory syndrome in children (MIS-C)5
Mettl14 sustains FOXP3 expression to promote the differentiation and functions of induced-regulatory T cells via the mTOR signaling pathway5
Alendronate modulates cytokine responses in healthy young individuals after BCG vaccination5
Mast cell activation signature as a potential biomarker in COVID-195
Cellular mechanisms underlying the impairment of macrophage efferocytosis5
Genetic and transcriptional dysregulation of innate antiviral immune pathways in type 1 diabetes5
BENTA disease or CARD11 gain-of-function? A novel variant with atypical features and a literature review5
USP7 - A novel target for controlling periodontal inflammation through modulation of macrophage polarization5
Rho-kinase inhibitors to deplete age-associated B cells in systemic autoimmunity5
Reduced TRIM expression correlates with anomalous CD4 T cell activation in systemic lupus Erythematosus and its clinical diagnostic potential5
Dextran sulfate sodium-induced gut microbiota dysbiosis aggravates liver injury in mice with S100-induced autoimmune hepatitis5
Eosinophils are sparse in homeostatic rectal tissue which impedes studying resident eosinophils5
Fighting the enemy within: Systemic immune defense against mucosal Salmonella infection5
Unveiling the hidden syndrome: The enigma of anti-transcobalamin receptor autoantibodies5
Elevated ascitic interleukin-36 receptor antagonist mediates CD8+ T cell exhaustion in vitro in liver cirrhotic patients with spontaneous bacterial peritonitis5
Immune checkpoint molecules in solid organ transplantation: A promising way to prevent rejection5
Human and mouse early B cell development: So similar but so different5
Tumor-associated NK cells facilitate tumor growth via NKp46 in immunocompetent murine hepatocellular carcinoma5
Insights into the relationship between persistent antibody secretion and metabolic programming – A question for single-cell analysis5
Could tolerance to DNA be broken in the gut in systemic lupus erythematosus?4
In adult X-CGD patients, regulatory T cells are expanded while activated T cells display a NOX2-independent ROS increase4
Unraveling the biological potential of skin fibroblast: responses to TNF-α, highlighting intracellular signaling pathways and secretome4
Alterations in chemokine receptor-ligand interactions and costimulatory molecules in DC-NK crosstalk: A novel therapeutic approach for pemphigus vulgaris4
Ursolic acid attenuates pseudo-allergic reactions via reducing MRGPRX2-mediated mast cell degranulation4
Gene therapy strategies for RAG1 deficiency: Challenges and breakthroughs4
A new experimental model to study shrimp allergy4
Acute and prolonged effects of interleukin-33 on cytokines in human cord blood-derived mast cells4
Human B-lymphopoiesis: Clinical challenges in B cell reconstitution and advances in in vitro modeling4
Enhanced immunoprotection against Acinetobacter baumannii infection: Synergistic effects of Bap and BauA in a murine model4
A novel MF59 and CpG1018 adjuvant combination enhances the humoral and cellular immune responses against a truncated varicella-zoster viral glycoprotein E4
The Th1/Th2 paradigm: A misrepresentation of helper T cell plasticity4
Science fact vs science fiction: A ChatGPT immunological review experiment gone awry4
The role of DAMP cytotoxic fractions in the immune markers’ disruption in patients with urgent surgical pathology and against the background of post-COVID-19 syndrome4
T cell landscape in the microenvironment of human solid tumors4
The intestinal microenvironment shapes macrophage and dendritic cell identity and function4
Single Cell Multiomic Approaches to Disentangle T Cell Heterogeneity4
Platelet-derived microvesicles modulate cytokine and lipid mediator profiles in THP-1 monocytes and macrophages4
Beyond HNA-1: The anti-HNA-3 autoantibody as a protagonist in autoimmune neutropenia4
Editorial Board4
LCK at the crossroad of immunodeficiency and autoimmunity: Mechanisms and therapeutic opportunities4
Corrigendum to “Matrine downregulates IL-33/ST2 expression in the central nervous system of rats with experimental autoimmune encephalomyelitis” [Immunol Lett. 178(2016) 97–104]4
Longitudinal analysis at pre- and post-flare of T peripheral helper and T follicular helper subsets in patients with systemic lupus erythematosus4
Lenvatinib-resistant liver cancer-derived HSP90α-containing extracellular vesicles enhance drug resistance via macrophage CXCL8 secretion4
COVID-19 acute respiratory distress syndrome promotes a specific alternative macrophage polarization4
IL-1β blockade prevents cell death and mucosal damage of the small intestine in a model of sterile inflammation4
Dysregulated Th17/Treg cell axis is correlated with local and systemic immune response in human intermediate uveitis4
Brain-resident regulatory T cells and their role in health and disease4
Silencing TRIM8 alleviates allergic asthma and suppressing Th2 differentiation through inhibiting NF-κB/NLRP3 signaling pathway4
New monogenic autoinflammatory diseases: 2021 year in review4
Corrigendum to “Metformin inhibits the pathogenic functions of AChR-specifc B and Th17 cells by targeting miR-146a” [Immunology Letters 250 (2022) 29–40 on Sep 13, 2022/ Manuscript ID: IMLET-D-22-00154
Innate immune activation beyond pathogens: Crosstalk between cellular repair pathways and DAMPs in homeostatic inflammation4
Editorial Board4
X-ray irradiation reduces ATP-dependent activation of NLRP3 inflammasome by inhibiting TWIK2 activity in macrophages3
Editorial Board3
NLRC3 affects the development of psoriasis by modulating the NF-κB signaling pathway mediated inflammatory response through its interaction with TRAF63
Adenine is an anti-inflammatory metabolite found to be more abundant in M-CSF over GM-CSF-differentiated human macrophages3
Functional alterations in colonic CD4+T and regulatory T cells drive immune imbalance in ulcerative colitis3
Differential structure and immunomodulatory functions of lipophosphoglycan between Leishmania spp3
The essential integration of sex and gender in immunological research3
A newly developed PLD1 inhibitor ameliorates rheumatoid arthritis by regulating pathogenic T and B cells and inhibiting osteoclast differentiation3
Herpesvirus entry mediator on effector memory CD8+ T cells mediates the effects of sterol ester (27:1/18:1) levels on critical sepsis3
Complement involvement in antiphospholipid syndrome3
In vitro analysis of azithromycin’s effect on J774 murine macrophages challenged with Aspergillus fumigatus3
Post-transcriptional control of T-cell development in the thymus3
Building the synapse engine to drive B lymphocyte function3
TLR3 and TLR7/8 agonists improve immunization outcome in nicotine exposed mice through different mechanisms3
CD36 as a double-edged sword in cancer3
Inhibition of FOSL1 alleviates inflammatory injury of otitis media by reducing ferroptosis3
The engineered agonistic anti-CD40 antibody potentiates the antitumor effects of β-glucan by resetting TAMs3
Restoration of Fli1 expression as a potential therapeutic approach in Systemic Sclerosis: Effects on age-associated B cells3
The frequencies of lymphocyte subsets on “day 30″ correlate with the clinical outcome of pediatric hematopoietic stem cell transplantation3
Conventional dendritic cells 2, the targeted antigen-presenting-cell, induces enhanced type 1 immune responses in mice immunized with CVC1302 in oil formulation3
Dysregulated serum lipid profile is associated with inflammation and disease activity in primary Sjögren's syndrome: a retrospective study in China3
Corrigendum to “Interleukin-40 is a promising biomarker associated with type 2 diabetes mellitus risk” [Immunology Letters 254 (2023) 1–5]3
Dermcidin-derived polypeptides: DCD(86-103) induced inflammatory reaction in the skin by activation of mast cells via ST23
Reduced CD37 expression in B cell subsets after stimulation and its clinical relevance in primary Sjögren's syndrome2
Identification of S100A9 as a target for diagnosis and treatment of Crohn’s Disease after Vedolizumab treatment failure2
Monocyte chemokine receptors as therapeutic targets in cardiovascular diseases2
Metabolic regulation of follicular helper T cell differentiation in a mouse model of lupus2
Triptolide alleviates acute gouty arthritis caused by monosodium urate crystals by modulating macrophage polarization and neutrophil activity2
PLC-IP3-ORAI pathway participates in the activation of the MRGPRB2 receptor in mouse peritoneal mast cells2
Musculin does not modulate the disease course of Experimental Autoimmune Encephalomyelitis and DSS colitis2
Long-term monocyte activation after coronary artery bypass grafting: An exploratory prospective observational study2
Brain inflammation in experimental autoimmune encephalomyelitis induced in Dark Agouti rats with spinal cord homogenate2
Editorial Board2
Dairy starters and fermented dairy products modulate gut mucosal immunity2
Weller et al., T-independent responses to polysaccharides in humans mobilize marginal zone B cells pre-diversified against gut bacterial antigens2
NK cell receptors in anti-tumor and healthy tissue protection: Mechanisms and therapeutic advances2
Identification and characterization of circulating and adipose tissue infiltrated CD20+ T cells from subjects with obesity that undergo bariatric surgery2
Importance of BCG Vaccination at birth in Pediatric Patients with Chronic Granulomatous Disease after Hematopoietic Stem Cell Transplantation in Developing Countries2
Expression of concern: “Interleukin-40 is a promising biomarker associated with type 2 diabetes mellitus risk” [Immunology Letters 254 (2023) 1–5]2
Emerging roles for RNA-binding proteins in T lymphocytes2
The influence of physical activity level and cytomegalovirus serostatus on the cytokine levels of young individuals2
ELF3 promotes the development of psoriasis through transcriptional up-regulation of ADAM8 expression2
Final step of B-cell differentiation into plasmablasts; the right time to activate plasma cell PIM2 kinase2
The effect of abnormal lipid metabolism on immunosenescence of the colonic lamina propria in mice of different ages2
The imbalance of circulating monocyte subgroups with a higher proportion of the CD14+CD16+CD163+ phenotype in patients with preeclampsia2
Phosphatidylserine promotes immunotherapy for airway allergy2
The role of IgA in gastrointestinal helminthiasis: A systematic review2
Does atopic dermatitis increase the risk of allergic contact dermatitis?2
Could we use PD-1 and PD-L1 expression on lymphocytes and monocytes as predictive markers for prognosis of acute biliary pancreatitis?2
CD73 in glioblastoma: Where are we now and what are the future directions?2
Ferroportin is a candidate regulator of dendritic cell-mediated immune tolerance2
Mechanisms of histamine release from mast cells beyond the high affinity IgE receptor in severe chronic spontaneous urticaria2
Elevated circulating CD19+CD24hiCD38hi B cells display pro-inflammatory phenotype in idiopathic membranous nephropathy2
Low IL-35 expression in CSF is associated with Neuro-Behcet Disease: Comparative analysis between parenchymal and Non-parenchymal NBD2
Interleukin-40 is a promising biomarker associated with type 2 diabetes mellitus risk2
Pentavalent outer membrane vesicles immunized mice sera confers passive protection against five prevalent pathotypes of diarrhoeagenic Escherichia coli in neonatal mice2
miR-125a-5p regulates Treg function by targeting Foxp3 in experimental autoimmune myasthenia gravis mice2
Synergistic regulation of microglia differentiation by CD93 and integrin β1 in the rat pneumococcal meningitis model2
Aloe-emodin relieves allergic contact dermatitis pruritus by inhibiting mast cell degranulation2
Editorial Board2
Single-cell sequencing has revealed a more complex array of thymic epithelial cells2
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