Immunology Letters

Article	Citations
The impact of ageing on monocytes and macrophages	147
Plasticity of monocyte development and monocyte fates	49
Immune reactivity during COVID-19: Implications for treatment	45
STAT3 inhibition protects against neuroinflammation and BACE1 upregulation induced by systemic inflammation	42
A comprehensive review on miR-146a molecular mechanisms in a wide spectrum of immune and non-immune inflammatory diseases	41
Macrophage-derived exosomes in cancers: Biogenesis, functions and therapeutic applications	41
Mechanisms underpinning poor antibody responses to vaccines in ageing	41
Psychedelics as a novel approach to treating autoimmune conditions	39
Gene regulation of intracellular adhesion molecule-1 (ICAM-1): A molecule with multiple functions	38
Brain-resident regulatory T cells and their role in health and disease	37
Sulforaphane inhibits NLRP3 inflammasome activation in microglia through Nrf2-mediated miRNA alteration	33
CD4+ Cytotoxic T cells – Phenotype, Function and Transcriptional Networks Controlling Their Differentiation Pathways	32
Targeting the PI3K/Akt/mTOR pathway: A therapeutic strategy in COVID-19 patients	30
Low levels of pro-resolving lipid mediators lipoxin-A4, resolvin-D1 and resolvin-E1 in patients with rheumatoid arthritis	30
Immunomodulation by heavy metals as a contributing factor to inflammatory diseases and autoimmune reactions: Cadmium as an example	29
How NETosis could drive “Post-COVID-19 syndrome” among survivors	28
Gut microbiota, immunity and pain	27
New aspects in the regulation of human B cell functions by complement receptors CR1, CR2, CR3 and CR4	26
PD-1, CTLA-4, LAG-3, and TIGIT: The roles of immune checkpoint receptors on the regulation of human NK cell phenotype and functions	25
“Cytokine storm”, not only in COVID-19 patients. Mini-review	25
The MALAT1-H19/miR-19b-3p axis can be a fingerprint for diabetic neuropathy	25
LncRNA GAS5 suppresses CD4+ T cell activation by upregulating E4BP4 via inhibiting miR-92a-3p in systemic lupus erythematosus	24
IgD−CD27− double negative (DN) B cells: Origins and functions in health and disease	24
Immunotherapy in treatment of leishmaniasis	24
Determination of the transcriptional level of long non-coding RNA NEAT-1, downstream target microRNAs, and genes targeted by microRNAs in diabetic neuropathy patients	23

Interplays between inflammasomes and viruses, bacteria (pathogenic and probiotic), yeasts and parasites	23
Molecular pathways in sepsis-induced cardiomyocyte pyroptosis: Novel finding on long non-coding RNA ZFAS1/miR-138–5p/SESN2 axis	22
Inflammasomes in dendritic cells: Friend or foe?	21
Dynamic role of macrophage CX3CR1 expression in inflammatory bowel disease	21
Life and death of microglia: Mechanisms governing microglial states and fates	20
SARS-CoV-2 Spike protein enhances ACE2 expression via facilitating Interferon effects in bronchial epithelium	20
T follicular cells: The regulators of germinal center homeostasis	20
Immunodeficiency and thymoma in Good syndrome: Two sides of the same coin	19
The Impact of New Immunological Therapeutic Strategies on Recurrent Miscarriage and Recurrent Implantation Failure	19
Highly activated TRAIL+ CD56bright NK cells are associated with the liver damage in HBV-LC patients	19
The roles of STAT6 in regulating B cell fate, activation, and function	18
TLR ligand loaded exosome mediated immunotherapy of established mammary Tumor in mice	18
A tabulated summary of the evidence on humoral and cellular responses to the SARS-CoV-2 Omicron VOC, as well as vaccine efficacy against this variant.	18
Combinatmarion treatment with Lactobacillus acidophilus LA-1, vitamin B, and curcumin ameliorates the progression of osteoarthritis by inhibiting the pro-inflammatory mediators	18
Efficient roles of miR-146a in cellular and molecular mechanisms of neuroinflammatory disorders: An effectual review in neuroimmunology	18
The onco-immunological implications of Fusobacterium nucleatum in breast cancer	18
Effect of Perfluorooctanesulfonic acid (PFOS) on immune cell development and function in mice	17
Science fact vs science fiction: A ChatGPT immunological review experiment gone awry	17
Regulation of cellular immunity by activating transcription factor 4	17
Increased circulating PD-1hiCXCR5- peripheral helper T cells are associated with disease severity of active ulcerative colitis patients	17
Increased peripheral helper T cells type 17 subset correlates with the severity of psoriasis vulgaris	17
Pathogen infection routes and host innate immunity: Lessons from insects	17
Oral tolerance: an updated review	16
Dairy starters and fermented dairy products modulate gut mucosal immunity	16
A small molecule inhibitor of caspase-1 inhibits NLRP3 inflammasome activation and pyroptosis to alleviate gouty inflammation	16
HLA-C*17 in COVID-19 patients: Hints for associations with severe clinical outcome and cardiovascular risk	15
Heterogeneity of tissue resident memory T cells	15
Long-term omalizumab efficacy in allergic rhinitis	14
Complement System in Alcohol-Associated Liver Disease	14
The crosstalk between H. pylori virulence factors and the PD1:PD-L1 immune checkpoint inhibitors in progression to gastric cancer	14
MicroRNA-144-3p enhances LPS induced septic acute lung injury in mice through downregulating Caveolin-2	14
Abnormal membrane-bound and soluble programmed death ligand 2 (PD-L2) expression in systemic lupus erythematosus is associated with disease activity	13
A fresh look at a neglected regulatory lineage: CD8+Foxp3+ Regulatory T cells	13
AURKA facilitates the psoriasis-related inflammation by impeding autophagy-mediated AIM2 inflammasome suppression	13
Are the emerging SARS-COV-2 mutations friend or foe?	13
MiR-30a-3p ameliorates oxidative stress in rheumatoid arthritis synovial fibroblasts via activation of Nrf2-ARE signaling pathway	13
Pulmonary vascular improvement in severe COVID-19 patients treated with tocilizumab	13
Effects of exercise and anti-PD-1 on the tumour microenvironment	12
Neuroimmune communication in infection and pain: Friends or foes?	12
Progress in research into the role of abnormal glycosylation modification in tumor immunity	12
Neutrophils-typical atypical antigen presenting cells?	12
Overexpression of pigment epithelium-derived factor in breast cancer cell-derived exosomes induces M1 polarization in macrophages	12
B cells as target for immunotherapy in rheumatic diseases – current status	12
Inflammatory status might direct ILC and NK cells to IL-17 expressing ILC3 and NK subsets in Behcet's disease	12
Global histone modification analysis reveals hypoacetylated H3 and H4 histones in B Cells from systemic lupus erythematosus patients	12
Galectin-3 in T cell-mediated immunopathology and autoimmunity	11
Role, function and regulation of the thymocyte selection-associated high mobility group box protein in CD8+ T cell exhaustion	11
Junctional adhesion molecule-A on dendritic cells regulates Th1 differentiation	11
Emerging regulatory roles of opioid peptides, endogenous morphine, and opioid receptor subtypes in immunomodulatory processes: Metabolic, behavioral, and evolutionary perspectives	11
The Immune Dysregulation of Common Variable Immunodeficiency Disorders	11

Will a little change do you good? A putative role of polymorphisms in COVID-19	11
Immune cell-mediated opioid analgesia	11
Protective effect of Bacteroides fragilis LPS on Escherichia coli LPS-induced inflammatory changes in human monocytic cells and in a rheumatoid arthritis mouse model	10
Immune system aging and the aging-related diseases in the COVID-19 era	10
Inflammatory alveolar macrophage-derived microvesicles damage lung epithelial cells and induce lung injury	10
The mitochondria-targeting antioxidant MitoQ alleviated lipopolysaccharide/ d-galactosamine-induced acute liver injury in mice	10
Leptin promotes glycolytic metabolism to induce dendritic cells activation via STAT3-HK2 pathway	10
Improved engraftment of human peripheral blood mononuclear cells in NOG MHC double knockout mice generated using CRISPR/Cas9	10
The neuro-immune axis in cancer: Relevance of the peripheral nervous system to the disease	9
Asthma, obesity, and microbiota: A complex immunological interaction	9
Circ_100395 impedes malignancy and glycolysis in papillary thyroid cancer: Involvement of PI3K/AKT/mTOR signaling pathway	9
Evaluation of an attenuated Listeria monocytogenes as a vaccine vector to control Helicobacter pylori infection	9
Benralizumab reduces eosinophils and inflammatory markers in patients with severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps: A pilot real-life study.	9
The occurrence of lupus nephritis is regulated by USP7-mediated JMJD3 stabilization	9
IL-17A and IFN-γ are Up-regulated in CD4 and γδ T Cells in Active Behcet's Disease Patients	9
OVOL2 inhibits macrophage M2 polarization by regulating IL-10 transcription, and thus inhibits the tumor metastasis by modulating the tumor microenvironment	9
The intestinal microenvironment shapes macrophage and dendritic cell identity and function	9
Addressing the key issue: Antigen-specific targeting of B cells in autoimmune diseases	8
Methylmercury chloride exposure exacerbates existing neurobehavioral and immune dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism	8
Comparison of three different COVID-19 vaccine platforms (CoronaVac, BTN162b2, and Ad5-nCoV) in individuals with and without prior COVID-19: Reactogenicity and neutralizing antibodies	8
Emerging roles of non-coding RNAs in the metabolic reprogramming of tumor-associated macrophages	8
Hemin acts as CD36 ligand to activate down-stream signalling to disturb immune responses and cytokine secretion from macrophages	8
BML-111, the lipoxin A4 agonist, modulates VEGF or CoCl2-induced migration, angiogenesis and permeability in tumor-derived endothelial cells	8
B19-VLPs as an effective delivery system for tumour antigens to induce humoral and cellular immune responses against triple negative breast cancer	8
CRISPR/Cas-based Human T cell Engineering: Basic Research and Clinical Application	7
Sepsis and multiple sclerosis: Causative links and outcomes	7
Distinct cell death markers identified in critical care patient survivors diagnosed with sepsis	7
CD36 as a double-edged sword in cancer	7
Metabolic regulation of follicular helper T cell differentiation in a mouse model of lupus	7
Preparation and in vitro activity of single chain antibodies against Alzheimer's disease	7
Immuno-hippo: Research progress of the hippo pathway in autoimmune disease	7
Insights into the role of complement system in the pathophysiology of endometriosis	7
Immune communication between the intestinal microbiota and the cardiovascular system	7
Aryl hydrocarbon receptor connects dysregulated immune cells to atherosclerosis	7
PD-1 Expression on CD8+CD28- T cells within inflammatory synovium is associated with Relapse: A cohort of Rheumatoid Arthritis	7
Targeted elimination of myeloid-derived suppressor cells via regulation of the STAT pathway alleviates tumor immunosuppression in neuroblastoma	7
GILT in tumor cells improves T cell-mediated anti-tumor immune surveillance	7
A brief history of epigenetics	7
Polarization of rheumatoid macrophages is regulated by the CDKN2B-AS1/ MIR497/TXNIP axis	7
IL-18 variant increases risk of enhanced HBV DNA replication in chronic hepatitis	6
Neuro-immune-metabolism: The tripod system of homeostasis	6
Different effectiveness of fungal pathogen-associated molecular patterns (PAMPs) in activating rat peritoneal mast cells	6
Abnormal thymic B cell activation and impaired T cell differentiation in pristane-induced lupus mice	6
Immunogenic profiling of Mycobacterium tuberculosis DosR protein Rv0569 reveals its ability to switch on Th1 based immunity	6
Dynamics of TIGIT and PD-1 expression on NK cells during the course of normal pregnancy	6
Epstein–Barr virus and genetic risk variants as determinants of T-bet+ B cell-driven autoimmune diseases	6
Plasticity and regulatory mechanisms of human ILC2 functions	6
Ageing of T-dependent B cell responses	6
VRK2 inhibition synergizes with PD-1 blockade to improve T cell responses	6
A novel antibody against the furin cleavage site of SARS-CoV-2 spike protein: Effects on proteolytic cleavage and ACE2 binding	6
Human and mouse early B cell development: So similar but so different	6
Dynamic monitoring of circulating CD8+ T and NK cell function in patients with septic shock	6
Antigenic competition in the generation of multi-virus-specific cell lines for immunotherapy of human cytomegalovirus, polyomavirus BK, Epstein-Barr virus and adenovirus infection in haematopoietic st	6
Separating the wheat from the chaff: Making sense of Treg heterogeneity for better adoptive cellular therapy	6
Age-related changes in the TRB and IGH repertoires in healthy adult males and females	6
Combining miR-23b exposure with mesenchymal stem cell transplantation enhances therapeutic effects on EAE	6
Mechanism of M2 macrophages modulating astrocyte polarization through the TGF-β/PI3K/Akt pathway	5
Serum profiles of pro-inflammatory and anti-inflammatory cytokines in non-hospitalized patients with mild/moderate COVID-19 infection.	5
Post-transcriptional control of T-cell development in the thymus	5
The miR-142 miRNAs: Shaping the naïve immune system	5
Emerging roles for RNA-binding proteins in T lymphocytes	5
Targeting plasma cells in systemic autoimmune rheumatic diseases – Promises and pitfalls	5
Recent preclinical study offers a promising clue: Role of regulatory T cells as biomarkers in migraine	5
Inactivated COVID-19 vaccines: potential concerns of antibody-dependent enhancement and original antigenic sin	5
A novel form of immunotherapy using antigen peptides conjugated on PD-L1 antibody	5
Hispolon inhibits RANKL induced osteoclast differentiation in vitro	5
Improved pulmonary function test (PFT) after 1 one year of Sublingual Immunotherapy (SLIT) in unison with pharmacotherapy in mild allergic asthmatics	5
Annickia polycarpa extract attenuates inflammation, neutrophil recruitment, and colon damage during colitis	5
Single-cell communication patterns and their intracellular information flow in synovial fibroblastic osteoarthritis and rheumatoid arthritis	5
CD73 in glioblastoma: Where are we now and what are the future directions?	5
Hyperactive neutrophils infiltrate vital organs of tumor bearing host and contribute to gradual systemic deterioration via upregulated NE, MPO and MMP-9 activity	5
Combination of mesenchymal stem cells and FK506 prolongs heart allograft survival by inhibiting TBK1/IRF3-regulated-IFN-γ production	5
Novel skewed usage of B-cell receptors in COVID-19 patients with various clinical presentations	5
MicroRNAs in inflammasomopathies	5
Construction of CAR-T cells targeting TM4SF1 and its anti-tumor capacity in ovarian cancer	5
Azithromycin and glucosamine may amplify the type 1 interferon response to RNA viruses in a complementary fashion	5
The modulatory effect of crotoxin and its phospholipase A2 subunit from Crotalus durissus terrificus venom on dendritic cells interferes with the generation of effector CD4+ T lymphocytes	5
Relevance of autoantibody profile with HLA-DRB1 and -DQB1 alleles in a group of Iranian systemic lupus erythematosus patients	5
Efferocytosis in lung mucosae: implications for health and disease	5
An assessment of toll-like receptor 7 and 8 gene polymorphisms with susceptibility to HIV-1 infection, AIDS development and response to antiretroviral therapy	4

McH-lpr/lpr-RA1 mice: A novel spontaneous mouse model of autoimmune sialadenitis	4
Harnessing immunomodulatory mechanisms of Trichinella spiralis to design novel nanomedical approaches for restoring self-tolerance in autoimmunity	4
Neutralization of IL-6 inhibits formation of autoreactive TH17 cells but does not prevent loss of renal function in experimental autoimmune glomerulonephritis	4
Untangling associations between immunoglobulin genotypes, repertoires and function	4
Impact of genetic variation on the molecular mimicry between Anoctamin-2 and Epstein-Barr virus nuclear antigen 1 in Multiple Sclerosis	4
Interleukin-40 is a promising biomarker associated with type 2 diabetes mellitus risk	4
New monogenic autoinflammatory diseases: 2021 year in review	4
Myocarditis development after COVID-19 vaccination in an immunodeficient case	4
HLA class II peptide-binding-region analysis reveals funneling of polymorphism in action	4
Pentavalent outer membrane vesicles immunized mice sera confers passive protection against five prevalent pathotypes of diarrhoeagenic Escherichia coli in neonatal mice	4
Lymphopenic condition enhanced the antitumor immunity of PD-1-knockout T cells mediated by CRISPR/Cas9 system in malignant melanoma	4
Characterization of testicular macrophage subpopulations in mice	4
Roles of leptin on the key effector cells of rheumatoid arthritis	4
Dengue virus induces interferon-β by activating RNA sensing pathways in megakaryocytes	4
The oncolytic virus VT09X optimizes immune checkpoint therapy in low immunogenic melanoma	4
Human toll-like receptor 8 (TLR8) in NK cells: Implication for cancer immunotherapy	4
A blinded multicenter investigation: Accentuated NK lymphocyte CD335 (NKp46) expression predicts reproductive failures after IVF.	4
Impact of gut microenvironment on epigenetic signatures of intestinal T helper cell subsets	4
A flow cytometric approach to study glucocorticoid receptor expression in immune cell subpopulations of genetically engineered mice	4
DCAF1 inhibits the NF-κB pathway by targeting p65	4
Immunoglobulin deficiency associated with a MAP2K1-related mutation causing cardio-facio-cutaneous syndrome	4
Conjugation of human serum albumin and flucloxacillin provokes specific immune response in HLA-B*57:01 transgenic mice	4
Vitamin A and vitamin D induced nuclear hormone receptor activation and its impact on B cell differentiation and immunoglobulin production	4
Modulation of oxidized low-density lipoprotein-affected macrophage efferocytosis by mitochondrial calcium uniporter in a murine model	4
3′UTR-HLA-G polymorphisms and circulating sHLA-G are associated with breast cancer: Evidence from a meta-analysis	4
PLC-IP3-ORAI pathway participates in the activation of the MRGPRB2 receptor in mouse peritoneal mast cells	4
Immune dysregulation as a leading principle for lymphoma development in diverse immunological backgrounds	4
Ficolin-3 in rheumatic fever and rheumatic heart disease	4
Macrophage-derived inflammation promotes pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension mice	4
Interstitial lung disease progression in patients with anti-aminoacyl transfer-RNA-synthetase autoantibodies is characterized by higher levels of sCD163	4
Insights into the relationship between persistent antibody secretion and metabolic programming – A question for single-cell analysis	4
Filarial infections compromise influenza vaccination efficacy: Lessons from the mouse	4
Dermcidin-derived polypeptides: DCD(86-103) induced inflammatory reaction in the skin by activation of mast cells via ST2	4
Potential contribution of the immune system to the emergence of renal diseases	4
TLR3 and TLR7/8 agonists improve immunization outcome in nicotine exposed mice through different mechanisms	3
Age-related changes of the human splenic marginal zone B cell compartment	3
Full seroconversion in initial non-responders with higher antibody levels after heterologous COVID-19 vaccination schedule.	3
Elevated CD38 expression characterizes impaired CD8+ T cell immune response in metastatic pleural effusions	3
Bcl2 like protine-12 (Bcl2L12) facilitates experimental airway allergic inflammation by inducing autocrine eotaxin in eosinophils	3
Proinflammatory S100A9 stimulates TLR4/NF-κB signaling pathways causing enhanced phagocytic capacity of microglial cells	3
Downregulation of DNMT3a expression by RNAi and its effect on NF-κBs expression of thymic epithelial cells	3
Inflammatory response-related genes predict prognosis in patients with HNSCC	3
SARS-CoV-2-specicific humoral immunity in convalescent patients with mild COVID-19 is supported by CD4+ T-cell help and negatively correlated with Alphacoronavirus-specific antibody titer	3
Differential expression of host protein biomarkers among symptomatic clinic attendees finally diagnosed with tuberculosis and other respiratory diseases with or without latent Mycobacterium tuberculos	3
Statistical and machine learning methods to study human CD4+ T cell proteome profiles	3
Oral Bacille Calmette-Guérin (BCG) vaccination induces long-term potentiation of memory immune response to Ovalbumin airway challenge in mice.	3
Synergistic regulation of microglia differentiation by CD93 and integrin β1 in the rat pneumococcal meningitis model	3
The role of IgA in gastrointestinal helminthiasis: A systematic review	3
Soluble CD137 as a potential biomarker for severe COVID-19	3
Antibodies to expanded virus antigen panels show elevated diagnostic sensitivities in multiple sclerosis and optic neuritis	3
Integrin αvβ6 cooperates with resiquimod to restore antigen-specific immune tolerance in airway allergy	3
Monocyte chemokine receptors as therapeutic targets in cardiovascular diseases	3
Eosinophils are dispensable for development of MOG35–55-induced experimental autoimmune encephalomyelitis in mice	3
Induction of food tolerance is dependent on intestinal inflammatory state	3
Determination of in vitro and in vivo immune response to recombinant cholesterol oxidase from Mycobacterium tuberculosis	3
IL-10 producing B cells regulated 1,3-β-glucan induced Th responses in coordinated with Treg	3
Clinical significance and role of CXCL16 in anti-neutrophil cytoplasmic autoantibody-associated vasculitis	3
Establishment of universal human embryonic stem cell lines	3
YAP1 induces marrow derived suppressor cell recruitment in Chlamydia trachomatis infection	3
Oral co-administration of bivalent protein r-BL with U-Omp19 elicits mucosal immune responses and reduces S. Typhimurium shedding in BALB/c mice	3
The Th1/Th2 paradigm: A misrepresentation of helper T cell plasticity	3
Rapamycin delays allograft rejection in obese graft recipients through induction of myeloid-derived suppressor cells	3
HIC1 interacts with FOXP3 multi protein complex: Novel pleiotropic mechanisms to regulate human regulatory T cell differentiation and function	3
Cellular mechanisms underlying the impairment of macrophage efferocytosis	3