Therapeutic Drug Monitoring

Article	Citations
Correlation Between N-Demethyl Imatinib Trough Concentration and Serious Adverse Reactions in Patients with Gastrointestinal Stromal Tumors: A Retrospective Cohort Study	133
Cobicistat as a Potential Booster of Ponatinib and Dasatinib Exposure in a CML Patient: A Case Study	85
Optimization of Teicoplanin Dosing Regimen in Adult Patients Using an Externally Evaluated Population Pharmacokinetic Model	53
PEG 400 Ion Suppression in Busulfan Detection by High-Performance Liquid Chromatography—Tandem Mass Spectrometry	48
Gentamicin Administration in Dialysis Patients: Before or After Hemodialysis?	39
In Silico Pharmacokinetics Evaluation of Forgiveness for Doravirine and Rilpivirine	33
Simultaneous Determination of Rifamycin Antibiotics and Their Active Metabolites in Human Plasma Using UHPLC-MS/MS to Evaluate Their Impact on Target Peak Concentrations: A Short Communication	26
Therapeutic Drug Monitoring Consulting Cannot be Ruled out by Model-Informed Precision Dosing	24
Tailoring Eculizumab Treatment: Evaluation of Model-Informed Precision Dosing for Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria and Atypical Hemolytic Uremic Syndrome	21
Broad-Spectrum Drug Screening Positivity Rates in Pediatrics and Adults: The Reference Laboratory Perspective	20
Prospective Validation of a Nomogram for Determining the Optimal Dose of Lamotrigine for Augmentation Therapy in Patients With Treatment-Resistant Depression	19
Ceftazidime Plasma Concentrations and Neurotoxicity: The Importance of Therapeutic Drug Monitoring in Patients Undergoing Different Modalities of Renal Replacement Therapy. A Grand Round	16
Limited Sampling Strategies Fail to Accurately Predict Mycophenolic Acid Area Under the Curve in Kidney Transplant Recipients and the Impact of Enterohepatic Recirculation	16
Dose Individualization of Cefepime for Febrile Neutropenia in Patients With Lymphoma or Multiple Myeloma: Implications for Therapeutic Drug Monitoring	16
Effects of Switching From Smoking to Vaping on Clozapine Concentration–Dose Ratios and Plasma Clozapine Concentrations: A Systematic Review of Case Reports	15
Machine Learning Modeling for Predicting Infliximab Pharmacokinetics in Pediatric and Young Adult Patients With Crohn Disease: Leveraging Ensemble Modeling With Synthetic and Real-World Data	15
Association of Vancomycin Trough Concentration and Clearance With Febrile Neutropenia in Pediatric Patients	14
Association Between Hematocrit- and Lymphocyte-Adjusted Tacrolimus Concentration and Clinical Outcomes in Dermatomyositis-Associated Interstitial Lung Disease: A Short Communication	14
Unmasking Tacrolimus Toxicity due to the Hacked Liver System	13
Systematic Critical Review of Genetic Factors Associated with Cisplatin-induced Ototoxicity: Canadian Pharmacogenomics Network for Drug Safety 2022 Update	13
Designer Benzodiazepines: Effects, Toxicity, and Interactions	13
Population Pharmacokinetics of Topiramate in Patients with Epilepsy Using Nonparametric Modeling	12
Risk of Underexposure and Lack of Efficacy of Cefiderocol by Reduced Dosing in Japanese Patients With Gram-Negative Bacterial Infections	12
Unpredictable Cyclosporine Clearance in a Korean Patient With Aplastic Anemia With Adverse Effects: A Case Study	12
Pharmacokinetic Boosting of Calcineurin Inhibitors in Transplantation: Pros, Cons, and Perspectives	12

Short-Term High-Fat Diet Alters Acetaminophen Metabolism in Healthy Individuals	12
Stabilization of Abiraterone in Human Plasma Using the Esterase Inhibitor Bis(4-nitrophenyl) Phosphate	12
Dose Monitoring of Lamotrigine Monotherapy in Pregnancy: Are Pregnant Women with Epilepsy Currently Optimally Managed? A Systematic Review	11
Nitrite Dipstick Urinalysis as a Point-Of-Care Test for Sodium Nitrite Poisoning	11
Unexpected Voriconazole Overexposure in a CYP2C19 Rapid Metabolizer Due to Inflammation-Induced Phenoconversion: A Short Communication	11
Modeling Approach with Therapeutic Drug Monitoring Data to Describe Time Course of Clozapine Exposure and Positive and Negative Syndrome Scale Scores	11
Allergy to Macrogol 400 and Titanium Dioxide (E171) as Potential Triggers of Anaphylactic Reaction After Dydrogesterone Intake	11
Recommendations for Assessing Methodological Quality in Systematic Reviews of Population Pharmacokinetic Models: A Systematic Review	11
Alternate Sampling Matrices for Therapeutic Drug Monitoring of Immunosuppressants	11
Rapid Detection of Lithium Concentrations in Oral Fluid	11
Development of a UHPLC-MS/MS Method for the Determination of Omadacycline in Human Plasma	11
Comparative Evaluation of Siemens Atellica and Abbott ARCHITECT Tacrolimus Immunoassays Against LC-MS/MS: A Short Communication	10
Therapeutic Drug Monitoring of Voriconazole in Patients with End-Stage Liver Disease	10
External Evaluation of Population Pharmacokinetic Models of Ustekinumab in Patients with Inflammatory Bowel Disease	10
Dried Blood Spot Sampling in the Monitoring of Anticancer Therapy for Solid Tumors: A Systematic Review	10
Generic Medicinal Products in Immunosuppressive Therapy—Should It be a Challenge for Therapeutic Drug Monitoring?	10
Implementation Strategies Addressing Stakeholder-Perceived Barriers and Enablers to the Establishment of a Beta-Lactam Antibiotic Therapeutic Drug Monitoring Program: A Qualitative Analysis	10
Catching the Culprit: Benzylpenicillin Neurotoxicity Confirmed by Therapeutic Drug Monitoring in a Critically Ill Patient With Continuous Venovenous Hemofiltration	10
Impact of Abiraterone Therapeutic Drug Monitoring on Cortisol as a Surrogate Biomarker of CYP17 Inhibition in Metastatic Prostate Cancer Treatment	9
Association of Torque Teno Virus DNA Load and Tacrolimus in Peripheral Blood Mononuclear Cells of Adult Kidney Transplant Patients	9
Dried Blood Spot Sampling for Therapeutic Drug Monitoring of Vancomycin and Creatinine in the Outpatient Parenteral Antimicrobial Therapy Service: A Qualitative Analysis of Facilitators and Barriers	9
Effect of Bedaquiline and Delamanid Pharmacokinetics on Sputum Culture Conversion and Adverse Events in Drug-Resistant Tuberculosis	9
Efficient Penetration of Terbinafine into Brain Abscesses in a Lung Transplant Recipient with Scedosporiosis: A Short Communication	9
Effect of CYP3A4 Methylation on Tacrolimus Pharmacokinetics	9
Evaluation of Three Quantification Methods for Monitoring Twelve Antiseizure Medications in Human Plasma by LC-MS/MS	9
Failure of Risk Assessment After Paracetamol Overdose—A Short Communication	9
Establishing and Extending the Use of Therapeutic Drug Monitoring in Neuropsychopharmacology	9
Factors Influencing Plasma Concentrations of Valproic Acid in Pediatric Patients With Epilepsy and the Clinical Significance of CYP2C9 Genotypes in Personalized Valproic Acid Therapy	9
Bridging the Gap: Advancing Pharmacogenetic Testing Through Comprehensive Implementation and Evaluation Strategies	9
Association of Cyclosporine Time in Therapeutic Range With Acute Cellular Rejection in Heart Transplantation: A 13-Year Single-Center Study	8
Population Pharmacokinetic Analysis of Drug–Drug Interactions Between Perampanel and Carbamazepine Using Enzyme Induction Model in Epileptic Patients	8
Ceftazidime Concentration is Correlated to the Glomerular Filtration Rate and Body Mass Index	8
In Memoriam: Professor Charles E. Pippenger	8
Simulation-Based Assessment of Empirical Amikacin Dosing in High-Risk Adults With Febrile Neutropenia and Hematological Malignancies Using Population Pharmacokinetic Modeling	8
The Effect of Age on Antipsychotic Serum Concentration in Males and Females: A Study Based on Therapeutic Drug Monitoring Data From 19,926 Patients	8
A Review of Blood-Based Microsampling Devices for Patient-Centered Application in Therapeutic Drug Monitoring	8
Need for Systematic and Comprehensive Toxicological Screening Protocols in Pediatric Poisoning Cases	8
Detecting the Undetectable: Analytical Strategies for Novel Psychoactive Substances	7
Apparent Elevation of Whole-Blood Tacrolimus Concentrations Following High-Dose Intravenous Immunoglobulin Therapy in Kidney Transplant Recipients	7
Therapeutic Drug Level Monitoring of Antipsychotics at an Inpatient Psychiatric Hospital	7
About an Acute Ethanol Intoxication Case of an Infant	7
A Narrative Review of Chromatographic Bioanalytical Methods for Quantifying Everolimus in Therapeutic Drug Monitoring Applications	7
Serum Concentration of Antidepressant Drugs in Geriatric Day Care Patients With Renal Insufficiency and Multimorbidity	7
Evaluation of Model-Informed Precision Dosing of Cefepime in Critically Ill Patients: A French Before–After Study	7
Mapping Therapeutic Drug Monitoring Research in Low- and Middle-Income Countries: A Scoping Review (2015–2024)	7
Limited Sampling Strategy Using End of Infusion and Six-Hour Concentrations Overestimates Intravenous Busulfan Clearance Compared With Standard Six-Point Sampling in Hematopoietic Stem Cell Transplant	7
Therapeutic Drug Monitoring and Pharmacogenomics of Thiopurines in Inflammatory Bowel Disease: International Guidelines Revisited	7
Mycophenolate Mofetil Dose Adjustment in Pediatric Kidney Transplant Recipients	7
New Predictive Equation for the Estimation of Plasma Concentrations of Formed Colistin in Patients Treated With Colistimethate Sodium for Multidrug-Resistant Gram-Negative Bacterial Infections	7
Utility of Therapeutic Drug Monitoring in Identifying Clinically Significant Interactions Between St. John's Wort and Prescription Drugs	7

Influence of Genetic Polymorphisms on Tacrolimus Pharmacokinetics in Whole Blood, Plasma, and Peripheral Blood Mononuclear Cells in Chinese Kidney Allograft Recipients	7
Impact of Glutathione S-Transferase Polymorphisms on Busulfan Pharmacokinetics and Outcomes of Hematopoietic Stem Cell Transplantation	7
Development of a Therapeutic Drug Monitoring Strategy for the Optimization of Vincristine Treatment in Pediatric Oncology Populations in Africa	7
Preliminary Determination of the Therapeutic Reference Range of Lurasidone in Chinese Patients and Analysis of the Factors Influencing Lurasidone Dose-Corrected Concentrations	7
Delayed Drug–Drug Interaction Between Antiviral Drugs and Tacrolimus in a Pancreatic Islet Transplant Recipient With SARS-CoV-2 Pneumonia	7
Diverse Drug Classes Partition into Human Sweat: Implications for Both Sweat Fundamentals and for Therapeutic Drug Monitoring	7
Correlation Between Ultrasonographic Response and Anti–Tumor Necrosis Factor Drug Levels in Crohn's disease	6
Clinical Relevance of High Plasma Trough Levels of the Kinase Inhibitors Crizotinib, Alectinib, Osimertinib, Dabrafenib, and Trametinib in NSCLC Patients	6
Urine Drug Testing: Service Models and Laboratory Practices to Meet Clinical Care Needs	6
Small Changes, Big Consequences? Assessment of the Impact of Design Changes in Microsampling Devices	6
Successful and Safe Real-Time TDM-Guided Treatment of Invasive Pulmonary and Cerebral Aspergillosis Using Low-Dose Isavuconazole in a Patient with Primary Biliary Cirrhosis: Grand Round/A Case Study	6
Utility of a TDM-Guided Expert Clinical Pharmacological Advice Program for Optimizing the Use of Novel Beta-Lactam/Beta-Lactamase Inhibitor Combinations and Cefiderocol in a Tertiary University Hospit	6
Effect of Tacrolimus Time in Therapeutic Range on Postoperative Recurrence in Patients Undergoing Liver Transplantation for Liver Cancer	6
Response to Panteghini “About Analytical Performance Specifications for Immunosuppressive Drug Measurements”	6
Therapeutic Drug Monitoring for Rufinamide in Japanese Patients With Epilepsy: Focus on Drug Interactions, Tolerability, and Clinical Effectiveness	6
High-Sensitivity and High-Throughput Quantification of Everolimus in Human Whole Blood Using Ultrahigh-Performance Liquid Chromatography Coupled With Tandem Mass Spectrometry	6
Risperidone Serum Levels in Depression: Insights From a Retrospective Therapeutic Drug Monitoring Study	6
Therapeutic Drug Monitoring of Guanfacine for Sedation in a Patient on Extracorporeal Membrane Oxygenation and Continuous Venovenous Hemofiltration: Grand Round/A Case Study	6
Donor-derived Cell-free DNA Does Not Improve the Detection of Acute Kidney Allograft Rejection Beyond Urinary CXCL9 and CXCL10	6
An Offline SPE-LC-MS/MS Method for Simultaneous Quantification of Tacrolimus, Cyclosporine A, Kynurenine, Tryptophan, and Creatinine Using Volumetric Absorptive Microsampling Device Mitra	6
Effect of Metformin on Plasma Exposure of Rifampicin, Isoniazid, and Pyrazinamide in Patients on Treatment for Pulmonary Tuberculosis	6
Novel Identification of Cysteinyl Derivatives of Toxic Clozapine Nitrenium Ions and the Effect of Valproic Acid on Metabolite Formation: A Study Using Reprocessed High-Resolution Mass Spectra of Analy	6
Ceftobiprole in Critically Ill Patients: Proposal for New Dosage Regimens	6
Towards Precision Dosing of Clozapine in Schizophrenia: External Evaluation of Population Pharmacokinetic Models and Bayesian Forecasting	6
Ribavirin for Paramyxovirus Infections in Hematopoietic Stem-Cell Transplant and Lung Transplant Recipients: Evaluation of an Optimized Dosing Regimen	6
Development and Validation of a High-Performance Liquid Chromatography–Ultraviolet Spectrometry Method for Ampicillin and Its Application in Routine Therapeutic Drug Monitoring of Intensive Care Patie	6
Detection of Δ8-Tetrahydrocannabinol and Δ9-Tetrahydrocannabinol Urinary Metabolites in Human Performance Urine Specimens in Broward and Miami-Dade Counties, Florida	6
Tacrolimus Conversion in CYP3A5*1 Expressers: From Immediate-Release to LCP Formulation	6
Optimization of Antimicrobial Stewardship Programs Using Therapeutic Drug Monitoring and Pharmacokinetics–Pharmacodynamics Protocols: A Cost-Benefit Review	6
Development and Validation of Linear Regression Models to Predict Plasma-Free Perampanel Concentrations Using Routine Clinical Data	5
Cyclosporin A Monitoring in Allogeneic Hematopoietic Stem-Cell Transplant Recipients: A Comparison Between Siemens Viva-ProE System and LC-MS/MS	5
The Case of Dolutegravir Plus Darunavir Antiretroviral Regimens: Is It Always Useful to Double the Drug Doses?	5
Limited Sampling Strategy of Rosuvastatin Single-Time-point Concentrations Accurately Estimate Exposure and Constitutive Transporter Activities in Healthy Adults	5
Peptide Mimotope-Enabled Quantification of Natalizumab Arm Exchange During Multiple Sclerosis Treatment	5
Optimum Methotrexate Exposure in Patients With Suspected or Confirmed CNS Invasive Hematological Malignancies: A Systematic Critical Review	5
Evaluation of Limited Sampling Strategies for Bayesian Estimation of Daptomycin Area Under the Concentration–Time Curve: A Short Communication	5
Safety and Tolerability of Single and Multiple Daily Oral Doses of Dried Kratom Leaf Powder in a Randomized Trial in Healthy Volunteers	5
Monitoring Simvastatin Adherence in Patients With Coronary Heart Disease: A Proof-of-Concept Study Based on Pharmacokinetic Measurements in Blood Plasma	5
Fluorescence-Based Lateral Flow Immunoassay for Quantification of Infliximab: Analytical and Clinical Performance Evaluation	5
Determining Plasma Tacrolimus Concentrations Using High-Performance LC-MS/MS in Renal Transplant Recipients	5
Quantification of the Conjugated Forms of Dichlorobisphenol A (3,3′-Cl2BPA) in Rat and Human Plasma Using HPLC-MS/MS	5
Development and Clinical Validation of a Volumetric Absorptive Capillary Microsampling Method for Quantification of Mycophenolic Acid and Mycophenolic Acid Glucuronide in Kidney Transplant Recipients	5
Deltamethrin Placental Transfer and Seasonal Pyrethroid Exposure: A Mother–Newborn Dyad Pilot Study	5
Tacrolimus Monitoring in Liver Transplant Recipients, Posttransplant Cholestasis: A Comparative Between 2 Commercial Immunoassays and a Liquid Chromatography-Tandem Mass Spectrometry Method	5
Comprehensive Review of the Application of Aptamer-Based Point-Of-Care Sensors for Therapeutic Drug Monitoring	5
A Strategy for Rescuing a Child From Clonazepam Poisoning: A Case Study	5
Development and Validation of a High-Performance Liquid Chromatography With Ultraviolet Detection Method to Facilitate Therapeutic Monitoring of Teicoplanin Using Dried Blood Spots	5
Pharmacokinetic Consideration of Venetoclax in Acute Myeloid Leukemia Patients: A Potential Candidate for TDM? A Short Communication	5
Correlation Between Escitalopram, Sertraline, and Fluoxetine Serum Levels and QTc Interval Prolongation in Children and Adolescents	5
Analytical Performance Specifications for Immunosuppressive Drug Measurements	5
Therapeutic Drug Monitoring of Immunosuppressive Drugs: A Field Constantly in Motion	5
Liquid Chromatography–Tandem Mass Spectrometry Method for Therapeutic Drug Monitoring of Dalbavancin in Plasma of Pediatric and Young Adult Patients	5
Real-world Plasma Exposure of Nirmatrelvir/Ritonavir in Chinese Hospitalized Patients With COVID-19: A Multicenter Retrospective Study	4
Pyrethroid Exposure in Premature Newborns: A Pilot Study on Materno–Fetal Transmission and Early Postnatal Evolution	4
CYP1A2 Polymorphism and Drug Co-administration Affect the Blood Levels and Adverse Effects of Pirfenidone	4
Therapeutic Drug Monitoring and Dosage Adjustments of Immunosuppressive Drugs When Combined With Nirmatrelvir/Ritonavir in Patients With COVID-19	4
Measurement of Hair Cortisol as a Retrospective Stress Marker: Effects of Prewashing, Pulverization, Temperature, and Sonication	4
Evaluation of the Homogenous Mobility Shift Assay for Infliximab and Adalimumab Anti-drug Antibody Detection in the Clinical Laboratory	4
Simultaneous Monitoring of 3 Antiviral Drugs in Serum Using Liquid Chromatography–Tandem Mass Spectrometry: Full Validation and Clinical Application	4
Lamotrigine Use in Lactating Women: Passage Into Breast Milk and Infant Exposure	4
Mechanism-Based Pharmacokinetic/Pharmacodynamic Model of Voriconazole for Predicting the Clinical Outcomes of Adult Patients With Invasive Aspergillosis	4
Passage of Venlafaxine in Human Milk During 12 Months of Lactation: A Case Report	4
Pharmacokinetic Variability of Rufinamide and Stiripentol in Children With Refractory Epilepsy: A Retrospective Study of Therapeutic Drug Monitoring From the National Epilepsy Centers in Denmark and N	4
Model-Informed Precision Dosing of Vancomycin in Vietnamese Children: Innovative Midpoint Concentration Monitoring Using 2 Bayesian Programs	4
Validation of Population Pharmacokinetic Models for Clozapine Dosage Prediction	4
Abstract for 22nd International Congress of Therapeutic Drug Monitoring and Clinical Toxicology, Banff, Alberta, Canada, September 15–18, 2024	4
Evaluation of a Highly Efficient Multidrug Biochip Array Technology for a Simultaneous and High-Throughput Urine Drug Screening in Clinical and Toxicological Settings	4
Effect of Carbamazepine on Darunavir Trough Concentrations: When the Dose Can Make the Difference—A Case Study	4
A Novel LC-MS/MS Method for Therapeutic Drug Monitoring of Baricitinib in Plasma of Pediatric Patients	4
Population Pharmacokinetics of Vancomycin in Patients Receiving Hemodialysis in a Malian and a French Center and Simulation of the Optimal Loading Dose	4
Volumetric Absorptive Microsampling to Enhance the Therapeutic Drug Monitoring of Tacrolimus and Mycophenolic Acid: A Systematic Review and Critical Assessment	4
Association Between the Intracellular Tacrolimus Concentration in CD3+ T Lymphocytes and CD14+ Monocytes and Acute Kidney Transplant Rejection	4
Optimizing Therapeutic Drug Monitoring in Pregnant Women: A Critical Literature Review	4
Population Pharmacokinetics and Limited Sampling Strategy of Mycophenolate Mofetil for Indian Patients With Lupus Nephritis	4
Variable Delta-9-Tetrahydrocannabinol Pharmacokinetics and Pharmacodynamics After Cannabis Smoking in Regular Users	4
Quantification of Ceftazidime in the Vitreous Humor Using Ultra-performance Convergence Chromatography–Tandem Mass Spectrometry	4
Model-Based Tacrolimus Follow-up Dosing in Adult Renal Transplant Recipients: A Simulation Trial	4
Optimizing Dried Blood Spot Sampling for Children and Adolescents With Autism Spectrum Disorder	4
Tobramycin a Priori Dosing Regimens Based on PopPK Model Simulations in Critically Ill Patients: Are They Transferable?	4
Toward Analytical Performance Specifications for Immunosuppressive Drug Quantification in Transplantation: An Opinion Article	4

Beyond the Usual: Novel Therapeutic Roles for Established Antidotes	4
Subtherapeutic Exposure of Ganciclovir in Children Despite Appropriate Dosing: A Short Communication	4
Relationship Between Clozapine:Norclozapine Ratio, Cognitive Function, and Employment Status in Patients with Treatment-Resistant Schizophrenia	4
Fingerprick Microsampling Methods Can Replace Venepuncture for Simultaneous Therapeutic Drug Monitoring of Tacrolimus, Mycophenolic Acid, and Prednisolone Concentrations in Adult Kidney Transplant Pat	4