OOIR: Observatory of International Research

Papers

(The TQCC of Neurotoxicology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Editorial Board	101
In silico identification of the potential molecular mechanisms involved in protective effects of prolactin on motor and memory deficits induced by 1,2-Diacetylbenzene in young and old rats	65
PEGylated superparamagnetic iron oxide nanoparticles (SPIONs) ameliorate learning and memory deficit in a rat model of Alzheimer’s disease: Potential participation of STIMs	53
Sex-specific associations between maternal phthalate exposure and neurodevelopmental outcomes in children at 2 years of age in the APrON cohort	48
Epoxiconazole caused oxidative stress related DNA damage and apoptosis in PC12 rat Pheochromocytoma	45
Abdominal surgery under ketamine anesthesia during second trimester impairs hippocampal learning and memory of offspring by regulating dendrite spine remodeling in rats	37
Preliminary Risk assessment for Acrylamide and Peripheral Neuropathy	36
Genkwanin suppresses MPP+-induced cytotoxicity by inhibiting TLR4/MyD88/NLRP3 inflammasome pathway in a cellular model of Parkinson’s disease	35
Effects of housing condition on the development and persistence of addictive-like behavior induced by toluene	34
Fruit ripening retardant Daminozide induces cognitive impairment, cell specific neurotoxicity, and genotoxicity in Drosophila melanogaster	33
Vitamin D attenuates monosodium glutamate-induced behavioural anomalies, metabolic dysregulation, cholinergic impairment, oxidative stress, and astrogliosis in rats	32
In vitro inhibition of glutathione-S-transferase by dopamine and its metabolites, 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylacetic acid	31
Reliability of a computer-based neurobehavioral assessment test battery for Bangladeshi adolescent children	29
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis	29
Maternal drinking behaviour and co-exposure from smoking during and after pregnancy in relation to the neurocognitive function of school-children in the rural Western Cape	27
Repeated exposure to chlorpyrifos is associated with a dose-dependent chronic neurobehavioral deficit in adult rats	27
Fenpyroximate induced cytotoxicity and genotoxicity in Wistar rat brain and in human neuroblastoma (SH-SY5Y) cells: Involvement of oxidative stress and apoptosis	27
Effects of route of administration on neural exposure to platinum-based chemotherapy treatment: a pharmacokinetic study in rat	26
Editorial Board	26
Neuroinflammation and white matter alterations in occupational manganese exposure assessed by diffusion basis spectrum imaging	26
Editorial Board	25
The efficacy of systemic administration of lipopolysaccharide in modelling pre-motor Parkinson’s disease in C57BL/6 mice	24
Brain region- and metal-specific effects of embedded metals in a shrapnel wound model in the rat	24
Ketamine-induced neurotoxicity is mediated through endoplasmic reticulum stress in vitro in STHdhQ7/Q7 cells	24
Pathological α-synuclein accumulation, CSF metabolites changes and brain microstructures in cynomolgus monkeys treated with 6-hydroxydopamine	23

Exogenous Otx2 protects midbrain dopaminergic neurons from MPP+ by interacting with ATP5a1 and promoting ATP synthesis	23
Effects of developmental exposure to FireMaster® 550 (FM 550) on microglia density, reactivity and morphology in a prosocial animal model	22
Cisplatin-induced changes in calcitonin gene-related peptide or TNF-α release in rat dorsal root ganglia in vitro model of neurotoxicity are not reverted by rosiglitazone	22
Early life exposure to lead and its association with parent-reported aggression and conduct problems during childhood and adolescence	22
Biochanin A protects SH-SY5Y cells against isoflurane-induced neurotoxicity by suppressing oxidative stress and apoptosis	21
Dose-related biphasic effect of the Parkinson’s disease neurotoxin MPTP, on the spread, accumulation, and toxicity of α-synuclein	21
Prenatal metal mixture concentrations and reward motivation in children	21
Formononetin attenuates H2O2-induced cell death through decreasing ROS level by PI3K/Akt-Nrf2-activated antioxidant gene expression and suppressing MAPK-regulated apoptosis in neuronal SH-SY5Y cells	20
Sex-dependent effects of short-term ethanol, energy drinks and acute noise exposure on hippocampal oxidative balance and glutamate transporter EAAT-1 during rat adolescence	20
Longitudinal effects of ketamine on cell proliferation and death in the CNS of zebrafish	20
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice	20
Impact of manganese accumulation on Na,K-ATPase expression and function in the cerebellum and striatum of C57Bl/6 mice	20
Investigating the neurotoxicity of environmental pollutants using zebrafish as a model organism: A review and recommendations for future work	19
Abeta peptides disrupt the barrier integrity and glucose metabolism of human induced pluripotent stem cell-derived brain microvascular endothelial cells	19
Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate	19
Neuroprotective effects of cannabidiol on dopaminergic neurodegeneration and α-synuclein accumulation in C. elegans models of Parkinson’s disease	19
Association of air pollution with risk and severity of obstructive sleep apnea: A systematic review and meta-analysis	18
In vivo neurophysiological assessment of in silico predictions of neurotoxicity: Citronellal, 3,4-dichloro-1-butene, and benzyl bromoacetate	18
Analysis of the long non-coding RNA and mRNA expression profiles associated with lidocaine-induced neurotoxicity in the spinal cord of a rat model	17
JM-20 affects GABA neurotransmission in Caenorhabditis elegans	17
Effects of acute insecticide exposure on neuronal activity in vitro in rat cortical cultures	17
Melatonin enhances the restoration of neurological impairments and cognitive deficits during drug withdrawal in methamphetamine-induced toxicity and endoplasmic reticulum stress in rats	17
Ferroptosis contributes to methylmercury-induced cytotoxicity in rat primary astrocytes and Buffalo rat liver cells	17
The bioavailability of ingested 26Al-labelled aluminium and aluminium compounds in the rat	17
Incomplete autophagy and increased cholesterol synthesis during neuronal cell death caused by a synthetic cannabinoid, CP-55,940	17
Developmental exposure of zebrafish to neonicotinoid pesticides: Long-term effects on neurobehavioral function	16
An efficient cellular image-based platform for high-content screening of neuroprotective agents against chemotherapy-induced neuropathy	16
Household based-pyrethroids on adult zebrafish (Danio rerio) exert behavioral and cholinergic changes in different brain regions	16
Modulatory effects of Cannabis sativa co-administration with tramadol and codeine on cognitive function in male rats	16
Fingolimod mitigates memory loss in a mouse model of Gulf War Illness amid decreasing the activation of microglia, protein kinase R, and NFκB	16
Synchrotron X-ray methods in the study of mercury neurotoxicology	16
An adverse outcome pathway for chemical-induced Parkinson’s disease: Calcium is key	16
Corrigendum to “Lambda-cyhalothrin enhances inflammation in nigrostriatal region in rats: Regulatory role of NF-κβ and JAK-STAT signaling” [NeuroToxicology 96 (2023) 101–117]	16
Fish consumption and its lipid modifying effects – A review of intervention studies	16
Association of urinary heavy metals co-exposure and adult depression: Modification of physical activity	15
Thiamethoxam evoked neural oxido-inflammatory stress in male rats through modulation of Nrf2/NF-kB/iNOS signaling and inflammatory cytokines: Neuroprotective effect of Silymarin	15
Neuronal exosomal miRNAs modulate mitochondrial functions and cell death in bystander neuronal cells under Parkinson’s disease stress conditions	15
Kainic acid induced hyperexcitability in thalamic reticular nucleus that initiates an inflammatory response through the HMGB1/TLR4 pathway	15
In silico identification of molecular mechanisms for stroke risk caused by heavy metals and their mixtures: Sponges and drugs involved	15
Harmaline toxicity on dorsal striatal neurons and its role in tremor	15
Protective mechanism of gold nanoparticles on human neural stem cells injured by β-amyloid protein through miR-21–5p/SOCS6 pathway	15
Blood pressure mediated the effects of cognitive function impairment related to aluminum exposure in Chinese aluminum smelting workers	14
Organophosphate insecticides disturb neuronal network development and function via non-AChE mediated mechanisms	14
Chlorpyrifos and parathion regulate oxidative stress differentially through the expression of paraoxonase 2 in human neuroblastoma cell	14
A zebrafish-based acoustic motor response (AMR) assay to evaluate chemical-induced developmental neurotoxicity	14
A review of monoamine oxidase (MAO) inhibitors in tobacco or tobacco smoke	13
Emerging roles of toll-like receptor 4 in chemotherapy-induced neurotoxicity	13
Receptor protein tyrosine phosphatase β/ζ regulates loss of neurogenesis in the mouse hippocampus following adolescent acute ethanol exposure	13
Air pollution, depressive and anxiety disorders, and brain effects: A systematic review	13
Bisphenol-A inhibits mitochondrial biogenesis via impairment of GFER mediated mitochondrial protein import in the rat brain hippocampus	13

The uses of 3D human brain organoids for neurotoxicity evaluations: A review	13
Improvement of non-motor and motor behavioral alterations associated with Parkinson-like disease in Drosophila melanogaster: Comparative effects of treatments with hesperidin and L-dopa	13
Acute radiofrequency electromagnetic radiation exposure impairs neurogenesis and causes neuronal DNA damage in the young rat brain	13
Astrocyte-derived exosomes carry microRNA-17-5p to protect neonatal rats from hypoxic-ischemic brain damage via inhibiting BNIP-2 expression	13
Evaluation of mRNA markers in differentiating human SH-SY5Y cells for estimation of developmental neurotoxicity	13
Vilazodone exposure during pregnancy: Effects on embryo-fetal development, pregnancy outcomes and fetal neurotoxicity by BDNF/Bax-Bcl2/5-HT mediated mechanisms	12
ATF5-mediated mitochondrial unfolded protein response protects against Pb-induced mitochondria damage in SH-SY5Y cell	12
Retraction notice to “Molecular mechanisms of neuroprotective effect of adjuvant therapy with phenytoin in pentylenetetrazole-induced seizures: Impact on Sirt1/NRF2 signaling pathways” [Neurotoxicolog	12
Early postnatal and concurrent exposure to metals and neurobehavioral outcomes at 5 years: Associations with individual environmental exposures and mixtures	12
The impact of electronic cigarette aerosol exposure on spatial memory formation: Modulation by orally administered vitamin E	12
BBPT attenuated 6-OHDA-induced toxicity by modulating oxidative stress, apoptotic, and inflammatory proteins in primary neurons and rat models of Parkinson's disease	12
New insights into pathogenesis of l-DOPA-induced dyskinesia	12
Exposure to an environmentally representative mixture of polybrominated diphenyl ethers (PBDEs) alters zebrafish neuromuscular development	12
Expression of concern “Assessment of the neuroprotective effect of selenium-loaded chitosan nanoparticles against silver nanoparticles-induced toxicity in rats” [Neurotoxicology 95 (2023) 232-243]	12
Combined chronic copper exposure and aging lead to neurotoxicity in vivo	12
Evaluation of the neurotoxic effects of engineered nanomaterials in C57BL/6J mice in 28-day oral exposure studies	12
CDN1163, a SERCA activator, causes intracellular Ca2+ leak, mitochondrial hyperpolarization and cell cycle arrest in mouse neuronal N2A cells	11
Bisphenol a affects neurodevelopmental gene expression, cognitive function, and neuromuscular synaptic morphology in Drosophila melanogaster	11
Tabernaemontana arborea and ibogaine induce paroxysmal EEG activity in freely moving mice: Involvement of serotonin 5-HT1A receptors	11
Liraglutide reduces oxidative stress and improves energy metabolism in methylglyoxal-induced SH-SY5Y cells	11
Effect of suvorexant on morphine tolerance and dependence in mice: Role of NMDA, AMPA, ERK and CREB proteins	11
Translational neurotoxicology − The 17th biennial meeting of the International Neurotoxicology Association	11
Teratogenic effects of maternal drug abuse on developing brain and underlying neurotransmitter mechanisms	11
Editorial Board	11
Developmental exposure to MDMA (ecstasy) in zebrafish embryos reproduces the neurotoxicity adverse outcome ‘lower motor activity’ described in humans	10
Prenatal exposure to a mixture of organophosphate esters and intelligence among 8-year-old children of the HOME Study	10
Neuroprotective effects of carbenoxolone against amyloid-beta 1–42 oligomer-induced neuroinflammation and cognitive decline in rats	10
ALDH2 inhibition by lead and ethanol elicits redox imbalance and mitochondrial dysfunction in SH-SY5Y human neuroblastoma cell line: Reversion by Alda-1	10
Editorial Board	10
Biomonitoring and bioaccessibility of environmental airborne manganese in relation to motor function in a healthy adult population	10
Organophosphorus pesticide exposure from house dust and parent-reported child behavior in Latino children from an orchard community	10
Preferential potentiation of AMPA-mediated currents in brainstem hypoglossal motoneurons by subchronic exposure of mice expressing the human superoxide dismutase 1 G93A gene mutation to neurotoxicant	10
Analysis of serum levels of organochlorine pesticides and related factors in Parkinson’s disease	10
Neuroprotective effects of dopamine D2 receptor agonist on neuroinflammatory injury in olfactory bulb neurons in vitro and in vivo in a mouse model of allergic rhinitis	10
Resveratrol prevents haloperidol-induced mitochondria dysfunction through the induction of autophagy in SH-SY5Y cells	10
Neuroprotective effect of quercetin and nano-quercetin against cyclophosphamide-induced oxidative stress in the rat brain: Role of Nrf2/ HO-1/Keap-1 signaling pathway	10
Preface	10
Editorial Board	10
Role of amyloid beta (25−35) neurotoxicity in the ferroptosis and necroptosis as modalities of regulated cell death in Alzheimer's disease	10
Net effects explains the benefits to children from maternal fish consumption despite methylmercury in fish	9
Nano polystyrene induced changes in anxiety and learning behaviour are mediated through oxidative stress and gene disturbance in mouse brain regions	9
Friedelin and Glutinol induce neuroprotection against ethanol induced neurotoxicity in pup’s brain through reduction of TNF-α, NF-kB, caspase-3 and PARP-1	9
Methylmercury effects on avian brains	9
Iron chelation prevents nigrostriatal neurodegeneration in a chronic methamphetamine mice model	9
Smoking, coffee intake, and Parkinson’s disease: Potential protective mechanisms and components	9
Resistance physical exercise alleviates lipopolysaccharide-triggered neuroinflammation in cortex and hippocampus of rats via purinergic signaling	9
Quantitative proteomics reveals the neurotoxicity of trimethyltin chloride on mitochondria in the hippocampus of mice	9
Relationship of mercury and selenium in ocean fish frequently consumed in the Seychelles: A comparison to levels in ocean fish consumed in the US	9
Developmental organophosphate flame retardant exposure disrupts adult hippocampal neurogenesis in Wistar rats	9
4-EA-NBOMe, an amphetamine derivative, alters glutamatergic synaptic transmission through 5-HT1A receptors on cortical neurons from Sprague Dawley rat and pyramidal neurons from C57BL/6 mouse	9
MR study on white matter injury in patients with acute diquat poisoning	9
Corrigendum to “Pharmacological evaluation of bromelain in mouse model of Alzheimer’s disease” [NeuroToxicology 90 (2022) 19–34]	9
Postnatal methylmercury exposure and neurodevelopmental outcomes at 7 years of age in the Seychelles Child Development Study Nutrition Cohort 2	9
Childhood exposure to pyrethroids and neurodevelopment in Canadian preschoolers	9
Associations between serum taurine concentrations in mothers and neonates and the children’s anthropometrics and early neurodevelopment: Results from the Seychelles Child Development Study, Nutrition	9
Neuroprotective potential of cinnamoyl derivatives against Parkinson’s disease indicators in Drosophila melanogaster and in silico models	8
Spontaneous partial recovery of striatal dopaminergic uptake despite nigral cell loss in asymptomatic MPTP-lesioned female minipigs	8
Selective effects of perinatal estrogen on proliferation and new neurons in hippocampus and piriform cortex of rats at weaning	8
Editorial Board	8
Multiple low-dose radiation-induced neuronal cysteine transporter expression and oxidative stress are rescued by N-acetylcysteine in neuronal SH-SY5Y cells	8
Comparison of neuropathology in rats following status epilepticus induced by diisopropylfluorophosphate and soman	8
Toxicity of copper and zinc alone and in combination in Caenorhabditis elegans model of Huntington's disease and protective effects of rutin	8
Editorial Board	8
Cranial irradiation-induced impairment of axonal transport and sexual function in male rats and imaging of the olfactory pathway by MRI	8
Olfactory tract/bulb metal concentration in Manganese-exposed mineworkers	8
Dietary selenium and mercury intakes from fish consumption during pregnancy: Seychelles Child Development Study Nutrition Cohort 2	8
Elevated whole blood manganese is associated with impaired cognition in older adults, NHANES 2013–2014 cycle	8
Lappaconitine inhibits glutamate release from rat cerebrocortical nerve terminals by suppressing Ca2+ influx and protein kinase A cascade	8
Fish consumption benefits health	8
Role of melatonin in TLR4-mediated inflammatory pathway in the MTPT-induced mouse model	8
AOP-based framework for predicting the joint action mode of di-(2-ethylhexyl) phthalate and bisphenol A co-exposure on autism spectrum disorder	8
Gray matter morphometric biomarkers for distinguishing manganese-exposed welders from healthy adults revealed by source-based morphometry	8
Developmental toxicity of bisphenol S in Caenorhabditis elegans and NODEF mice	8
Microglial responses to inflammatory challenge in adult rats altered by developmental exposure to polychlorinated biphenyls in a sex-specific manner	8