OOIR: Observatory of International Research

Papers

(The TQCC of Neurotoxicology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Editorial Board	211
Chlorpyrifos and parathion regulate oxidative stress differentially through the expression of paraoxonase 2 in human neuroblastoma cell	196
Evaluation of mRNA markers in differentiating human SH-SY5Y cells for estimation of developmental neurotoxicity	60
Behavioural, biochemical and functional phenotyping of subchronic exposure to chlordecone in mice	52
JM-20 affects GABA neurotransmission in Caenorhabditis elegans	48
In silico identification of molecular mechanisms for stroke risk caused by heavy metals and their mixtures: Sponges and drugs involved	45
Early-stage quality—late-stage confidence: Neural induction quality control as a key to reproducible MEA-based neurotoxicity assays	41
Ketamine-induced neurotoxicity is mediated through endoplasmic reticulum stress in vitro in STHdhQ7/Q7 cells	41
Structural neuroimaging of the planning network in Inuit adolescents prenatally exposed to lead	39
The uses of 3D human brain organoids for neurotoxicity evaluations: A review	37
Household based-pyrethroids on adult zebrafish (Danio rerio) exert behavioral and cholinergic changes in different brain regions	37
Editorial Board	36
The contributions of neonatal inhalation of copper to air pollution-induced neurodevelopmental outcomes in mice	35
PRDX1 affects acrylamide-induced neural damage through the PTEN/AKT signaling pathway	33
Amphetamine-induced neurite injury in PC12 cells through inhibiting GAP-43 pathway	33
ALDH2 inhibition by lead and ethanol elicits redox imbalance and mitochondrial dysfunction in SH-SY5Y human neuroblastoma cell line: Reversion by Alda-1	30
The combined effects of HSV-1 glycoprotein D and aluminum hydroxide on human neuroblastoma cells: Insights into oxidative DNA damage, apoptosis, and epigenetic modifications	30
Chronic cisplatin treatment in young mice induces long-term complications in the peripheral nervous system in a sex-dependent manner	30
Blockade of NMDA-receptors mitigates autistic and cognitive behaviors via modulation of TLR-4/NLRP3 inflammasomes and microglia/astrocyte crosstalk in rat model of autism	29
Nano polystyrene induced changes in anxiety and learning behaviour are mediated through oxidative stress and gene disturbance in mouse brain regions	29
Spontaneous partial recovery of striatal dopaminergic uptake despite nigral cell loss in asymptomatic MPTP-lesioned female minipigs	28
Repeated neonatal sevoflurane exposure causes adolescent anxiety/depression via microglial P2Y12R-Wnt/β-catenin pathway-mediated neurogenesis deficits	28
Predicted versus observed activity of PCB mixtures toward the ryanodine receptor	28
The effects of oral gestational particulate matter 10 exposure: Insights into neurodevelopmental milestones, inhibitory control, adult sociability, and object recognition	27
Cadmium exposure at low environmental levels induces cognitive decline in aged male mice	26

Prenatal BPB/BPAF exposure induces depression-like behavior in male mice offspring via compound-specific transcriptional dysregulation and neurodevelopmental pathway alterations	26
DDT exposure induces microglial activation and disease-associated microglial signatures: Relevance to mechanisms of Alzheimer’s disease	26
Neuroprotective effect of quercetin and nano-quercetin against cyclophosphamide-induced oxidative stress in the rat brain: Role of Nrf2/ HO-1/Keap-1 signaling pathway	26
The role of ER/ERK/CREB pathway mediated mitophagy in bisphenol F-induced cognitive function changes in young female rats	26
Editorial Board	25
Mechanisms by which neuroinflammation modulates GABAergic neurotransmission in the hippocampus of hyperammonemic rats	25
Postnatal methylmercury exposure and neurodevelopmental outcomes at 7 years of age in the Seychelles Child Development Study Nutrition Cohort 2	24
In silico and In vivo protective effect of biochanin-A mitigating doxorubicin- induced cognitive deficits and neuroinflammation: Insights to the role of p-Tau and miR-132	24
4-EA-NBOMe, an amphetamine derivative, alters glutamatergic synaptic transmission through 5-HT1A receptors on cortical neurons from Sprague Dawley rat and pyramidal neurons from C57BL/6 mouse	24
Retraction notice to “Tranilast ameliorated subchronic silver nanoparticles-induced cerebral toxicity in rats: Effect on TLR4/NLRP3 and Nrf-2” [NeuroToxicology 82 (2021) 167–176]	23
Corrigendum to “Jatamansinol from Nardostachys jatamansi (D.Don) DC. Protects Aβ42-induced neurotoxicity in Alzheimer's disease Drosophila model”, [Neurotoxicology 90 (2022) 62–78]	22
Targeting glutamate receptors with IEM-1925: A strategy against soman-induced status epilepticus and neurodegeneration	22
Radon-Related Increases in Depressive Symptoms are Explained by Amygdala Morphology and External Locus of Control	21
Brief postnatal exposure to bisphenol A affects apoptosis and gene expression in the medial prefrontal cortex and social behavior in rats with sex specificity	21
Mechanisms of developmental neurotoxicity of Dechlorane Plus, a recently identified persistent organic pollutant: An in silico study	20
Association of plasma metals with resting-state functional connectivity in ischemic stroke	19
Cannabis use in Parkinson’s disease: Patient access to medical cannabis and physician perspective on product safety	19
Ketamine modulates neural stem cell differentiation by regulating TRPC3 expression through the GSK3β/β-catenin pathway	19
Ketamine's brain spatial distribution and metabolic effects in a mouse model of anxiety: Insight into in situ mass spectrometry imaging and metabolomics methods	19
Hippocampal apoptosis: Molecular mechanisms triggered by toxic cannabinoid exposure: A narrative review	19
The effect of graphene oxide administration on the brains of male mice: Behavioral study and assessment of oxidative stress	19
Repeated toluene and cyclohexane inhalation produces differential effects on HPA and HPT axes in adolescent male rats	18
Selenium attenuates paclitaxel-induced peripheral neuropathy by suppressing oxidative stress, inflammation, and apoptosis in rat sciatic nerve	18
Polychlorinated biphenyls (PCBs) exposure and cognitive function in adults: A systematic review of epidemiologic evidence and risk of bias assessment	18
Ameliorating age-dependent effects of resveratrol on VPA-induced social impairments and anxiety-like behaviors in a rat model of neurodevelopmental disorder	18
Tropospheric ozone effect on olfactory perception and olfactory bulb dopaminergic interneuron excitability	18
Long-term exposure to ionic liquid [C8mim]Br induces the potential risk of anxiety and memory deterioration through disturbing neurotransmitter systems	18
Altered development in rodent brain cells after 900 MHz radiofrequency exposure	18
Infant neurodevelopment and behavior in Guadeloupe after lead exposure and Zika maternal infection during pregnancy	18
Neuronal degeneration, mitochondrial dysfunction, and disturbance of movements induced by rotenone in the ascidian Styela plicata	17
Sex-associated variables – A framework for neurotoxicology	17
PCB 37 (3,4, 4’-trichlorobiphenyl) increased apoptosis and modulated neuronal morphogenesis in primary rat cortical neuron-glia cocultures in a concentration-, sex-, age-, and CREB-dependent manner	17
Identification of neurotoxicology (NT)/developmental neurotoxicology (DNT) adverse outcome pathways and key event linkages with in vitro DNT screening assays	16
The role of carbon monoxide in aerotoxic syndrome	16
Do toenail manganese and iron levels reflect brain metal levels or brain metabolism in welders?	16
Assessing neuropsychological disorders affecting pottery workers occupationally exposed to air pollutants	16
Synergic control in asymptomatic welders during multi-finger force exertion and load releasing while standing	15
Lead (Pb) exposure results in cell type specific changes in the mouse retina and optic nerve	15
Predicting structural features of selected flavonoids responsible for neuroprotection in a Drosophila model of Parkinson’s disease	15
Evaluation of sub-chronic toxicity of melamine via systematic or oral delivery in adult zebrafish based on behavioral endpoints	15
Long-term occupational exhaust fumes exposure and delayed cognitive impairment in older adults: A cross-sectional study in U.S	15
Ozone in neurodegeneration: An environmental toxicant or a therapeutic hormetin?	15
Impacts of neonatal methylmercury on behavioral flexibility and learning in spatial discrimination reversal and visual signal detection tasks	15
Developmental lead exposure affects dopaminergic neuron morphology and modifies basal slowing response in Caenorhabditis elegans: Effects of ethanol	14
Subchronic Residual Oil Fly Ash (ROFA) exposure induces oxidative stress in brain, lung, and cardiac tissues and promotes neuroinflammation, with partial attenuation by taurine	14
Persisting neurobehavioral consequences of daily or intermittent paternal cannabis administration in F1 and F2 Rats	14
Unraveling the effects of prenatal anesthesia on neurodevelopment: A review of current evidence and future directions	14
A hyperpolarization-activated cyclic nucleotide-gated channel inhibitor mitigates brain mitochondrial oxidative stress, but does not affect other neuropathological	14
Combinations of classical and non-classical voltage dependent potassium channel openers suppress nociceptor discharge and reverse chronic pain signs in a rat model of Gulf War illness	14
Impact of chronic exposure to legacy environmental contaminants on the corpus callosum microstructure: A diffusion MRI study of Inuit adolescents	14

The inhibitory influence of carvacrol on behavioral modifications, brain oxidation, and general inflammation triggered by paraquat exposure through inhalation	14
Age-dependent effects of hyperhomocysteinemia on neural differentiation and retinal development	14
Vitamin A ameliorates valproic acid-induced autism-like symptoms in developing zebrafish larvae by attenuating oxidative stress and apoptosis	14
Evaluating how occupational exposure to organophosphates and pyrethroids impacts ADHD severity in Egyptian male adolescents	14
Adult-onset epilepsy and hippocampal pathology in a California sea lion (Zalophus californianus): A case study of suspected in utero exposure to domoic acid	14
Human blood markers of cholinergic neurotoxicity and neuropathy: A useful guide for laboratory applications	13
An efficient cellular image-based platform for high-content screening of neuroprotective agents against chemotherapy-induced neuropathy	13
Welding techniques and manganese concentrations in blood and brain: Results from the WELDFUMES study	13
Neuroprotective effect of Licochalcone A against aluminum chloride-induced neurotoxicity by reducing Aβ accumulation, oxidative stress and inflammatory reaction	13
Systemic administration of lipopolysaccharide induces hyperexcitability of prelimbic neurons via modulation of sodium and potassium currents	13
Identification of neural-relevant toxcast high-throughput assay intended gene targets: Applicability to neurotoxicity and neurotoxicant putative molecular initiating events	13
Environmental concentrations of glyphosate through direct or parental exposure alter nervous system development and reduce the fertility rate in zebrafish	13
The impact of electronic cigarette aerosol exposure on spatial memory formation: Modulation by orally administered vitamin E	13
Luteolin protects mouse hippocampal neuronal cells against isoflurane-induced neurotoxicity through miR-214/PTEN/Akt pathway	13
Gut microbiota: A critical regulator of oxaliplatin-induced peripheral neurotoxicity development	13
Impact of early adolescent lead exposure on brain function and response: Findings from a Chinese cohort	13
Preliminary evidence of polyvinyl chloride microplastics inducing ferroptosis in the cerebral cortex of ducks	13
Lifetime air pollution exposure, cognitive deficits, and brain imaging outcomes: A systematic review	13
Dynamic dose–time proteomic profiling of cadmium exposure in rat prefrontal cortex	12
Abnormal lipid metabolism and inflammatory response induced by aluminum led to the cognitive decline in mice	12
In silico identification of the potential molecular mechanisms involved in protective effects of prolactin on motor and memory deficits induced by 1,2-Diacetylbenzene in young and old rats	12
A review of monoamine oxidase (MAO) inhibitors in tobacco or tobacco smoke	12
Emerging roles of toll-like receptor 4 in chemotherapy-induced neurotoxicity	12
Mechanisms of micro- and nanoplastics on blood-brain barrier crossing and neurotoxicity: Current evidence and future perspectives	12
Longitudinal changes in pallidal index and their associations with urinary manganese and CaNa₂EDTA chelation	12
Sex-specific associations between maternal phthalate exposure and neurodevelopmental outcomes in children at 2 years of age in the APrON cohort	12
Synchrotron X-ray methods in the study of mercury neurotoxicology	12
Toluene, styrene and methyl-ethyl-ketone inhalation: Effects on the power of cortical oscillations in rats	12
Early life exposure to lead and its association with parent-reported aggression and conduct problems during childhood and adolescence	12
An adverse outcome pathway for chemical-induced Parkinson’s disease: Calcium is key	12
Cadmium exposure and cognitive impairment in middle-aged and older adults: Linking neurocognitive deficits with systemic inflammation	11
Methylmercury effects on avian brains	11
Retraction notice to “Neurotoxic effects of pregabalin dependence on the brain frontal cortex in adult male albino rats” [NeuroToxicology 83 (2021) 146–155]	11
Fish consumption benefits health	11
Paraquat-induced rodent models of Parkinson’s disease: A PRISMA-compliant systematic review and meta-analysis	11
Retraction notice to “Melatonin rescues the mice brain against cisplatin-induced neurodegeneration, an insight into antioxidant and anti-inflammatory effects” [Neurotoxicology 87 (2021) 1–10]	11
Developmental neurotoxicity of bisphenol F and bisphenol S in animal model systems: A literature review	11
Protective mechanism of gold nanoparticles on human neural stem cells injured by β-amyloid protein through miR-21–5p/SOCS6 pathway	11
Neuroprotective potential of cinnamoyl derivatives against Parkinson’s disease indicators in Drosophila melanogaster and in silico models	11
Editorial Board	11
Brain MRI iron deposition and serum iron with multiple sclerosis: Evidence from a Mendelian randomization study	11
Gray matter morphometric biomarkers for distinguishing manganese-exposed welders from healthy adults revealed by source-based morphometry	11
Smoking, coffee intake, and Parkinson’s disease: Potential protective mechanisms and components	10
Editorial Board	10
Editorial Board	10
Diazepam and exercise training combination synergistically reduces lipopolysaccharide-induced anxiety-like behavior and oxidative stress in the prefrontal cortex of mice	10
C. elegans as a powerful model for neurotoxicity assessment	10
Association of midlife air pollution and road proximity exposure with 29-year cognitive decline	10
Assessing CaMPARI as new approach methodology for evaluating neurotoxicity	10
Liraglutide reduces oxidative stress and improves energy metabolism in methylglyoxal-induced SH-SY5Y cells	10
Blood glucose mediated the effects of cognitive function impairment related to aluminum exposure in Chinese aluminum smelting workers	10
Occupational exposure to pesticides as a potential risk factor for epilepsy	10
Manganese accumulation in red blood cells as a biomarker of manganese exposure and neurotoxicity	10
Brain gray matter atrophy in adult population with cognitive impairment due to chronic cadmium exposure	10
Childhood exposure to pyrethroids and neurodevelopment in Canadian preschoolers	10
Proteomic profiling reveals neuronal ion channel dysregulation and cellular responses to DNA damage-induced cell cycle arrest and senescence in human neuroblastoma SH-SY5Y cells exposed to cypermethri	10
The stoichiometry of the α4β2 neuronal nicotinic acetylcholine receptors determines the pharmacological properties of the neonicotinoids, and recently introduced butenolide and sulfoximine	10
Time-dependent neuropathology in rats following organophosphate-induced status epilepticus	10
Comparison of predictive validity of two autism spectrum disorder rat models: Behavioural investigations	9
Larval zebrafish as a translational model for neurotoxicity screening of emerging psychoactive substances	9
Effects of mixed metal exposures on MRI diffusion features in the medial temporal lobe	9
α-synuclein-lack expression rescues methamphetamine-induced mossy fiber degeneration in dorsal hippocampal CA3	9
Endoplasmic reticulum stress-induced CHOP activation mediates NLRP3 inflammasome-dependent pyroptosis in BDE-47-induced cognitive dysfunction	9
Childhood exposure to organophosphate pesticides: Functional connectivity and working memory in adolescents	9
Maternal exposure to polystyrene microplastics impairs social behavior in mouse offspring with a potential neurotoxicity	9
Synthetic cannabidiol analogues exhibit lower toxicity than cannabidiol and protect against ethanol-induced apoptosis in SH-SY5Y cells	9
Understanding similarities and differences of FASD in three zebrafish populations	9
From clinical observation to experimental validation: Investigating the neurotoxic impact of dimethylacetamide	9
A larval zebrafish assay of the potency of sensory irritants correlates well with human TRPA1 activation and irritancy data	9
Social deficits in mice prenatally exposed to valproic acid are intergenerationally inherited and rescued by social enrichment	9
Pesticide exposure and cortical brain activation among farmworkers in Costa Rica	9
PHLDA1 promotes sevoflurane-induced pyroptosis of neuronal cells in developing rats through TRAF6-mediated activation of Rac1	9
Evaluating the toxic mechanism of 1,2-diacetylbenzene in neural cells/tissues: The favorable impact of silibinin	9
Chlorpyrifos, permethrin and cyfluthrin effect on cell survival, permeability, and tight junction in an in-vitro model of the human blood-brain barrier (BBB)	9