Neurotoxicology

Papers
(The TQCC of Neurotoxicology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
The SH-SY5Y human neuroblastoma cell line, a relevant in vitro cell model for investigating neurotoxicology in human: Focus on organic pollutants89
Neurotoxic potential of polystyrene nanoplastics in primary cells originating from mouse brain65
Quercetin provides protection against the peripheral nerve damage caused by vincristine in rats by suppressing caspase 3, NF-κB, ATF-6 pathways and activating Nrf2, Akt pathways62
Vincristine-induced peripheral neuropathy: A mini-review57
Air pollution, depressive and anxiety disorders, and brain effects: A systematic review57
Epigenetic influence of environmentally neurotoxic metals52
Mitochondrial iron metabolism and neurodegenerative diseases48
Baicalein protects against MPP+/MPTP-induced neurotoxicity by ameliorating oxidative stress in SH-SY5Y cells and mouse model of Parkinson’s disease47
Formononetin attenuates H2O2-induced cell death through decreasing ROS level by PI3K/Akt-Nrf2-activated antioxidant gene expression and suppressing MAPK-regulated apoptosis in neuronal SH-SY5Y cells40
Prenatal PM2.5 exposure and behavioral development in children from Mexico City39
Association between aluminum in drinking water and incident Alzheimer’s disease in the Canadian Study of Health and Aging cohort36
Anti-inflammatory and neuroprotective effects of natural cordycepin in rotenone-induced PD models through inhibiting Drp1-mediated mitochondrial fission35
Astrocyte-derived exosomes carry microRNA-17-5p to protect neonatal rats from hypoxic-ischemic brain damage via inhibiting BNIP-2 expression35
Neuroprotective effect of chrysin on isoniazid-induced neurotoxicity via suppression of oxidative stress, inflammation and apoptosis in rats34
Pesticides applied to crops and amyotrophic lateral sclerosis risk in the U.S33
Mercury: selenium interactions and health implications32
Neuromodulatory effects of hesperidin against sodium fluoride-induced neurotoxicity in rats: Involvement of neuroinflammation, endoplasmic reticulum stress, apoptosis and autophagy32
IDO-1 inhibition protects against neuroinflammation, oxidative stress and mitochondrial dysfunction in 6-OHDA induced murine model of Parkinson’s disease29
Protective effect of alpha-linoleic acid on Aβ-induced oxidative stress, neuroinflammation, and memory impairment by alteration of α7 nAChR and NMDAR gene expression in the hippocampus of rats29
Association of arsenic exposure and cognitive impairment: A population-based cross-sectional study in China28
Impact of environmental toxicants on p38- and ERK-MAPK signaling pathways in the central nervous system28
Taurine improves neuron injuries and cognitive impairment in a mouse Parkinson’s disease model through inhibition of microglial activation27
Neuroprotective effects of catechin and quercetin in experimental Parkinsonism through modulation of dopamine metabolism and expression of IL-1β, TNF-α, NF-κB, IκKB, and p53 genes in male Wistar rats27
Metabolic profiling in human SH-SY5Y neuronal cells exposed to perfluorooctanoic acid (PFOA)27
Polychlorinated biphenyls induce oxidative stress and metabolic responses in astrocytes27
Mechanisms of oxidative stress in methylmercury-induced neurodevelopmental toxicity26
Critical windows of susceptibility in the association between manganese and neurocognition in Italian adolescents living near ferro-manganese industry25
The ameliorative effect of nanoselenium on histopathological and biochemical alterations induced by melamine toxicity on the brain of adult male albino rats24
Does paraquat cause Parkinson’s disease? A review of reviews24
Investigation of the effects of berberine on bortezomib-induced sciatic nerve and spinal cord damage in rats through pathways involved in oxidative stress and neuro-inflammation23
Neuroprotective effects of cannabidiol on dopaminergic neurodegeneration and α-synuclein accumulation in C. elegans models of Parkinson’s disease23
AlCl3 induced learning and memory deficit in zebrafish23
Oxidative stress and decreased dopamine levels induced by imidacloprid exposure cause behavioral changes in a neurodevelopmental disorder model in Drosophila melanogaster22
PEGylated superparamagnetic iron oxide nanoparticles (SPIONs) ameliorate learning and memory deficit in a rat model of Alzheimer’s disease: Potential participation of STIMs22
Arsenic induces autophagy-dependent apoptosis via Akt inactivation and AMPK activation signaling pathways leading to neuronal cell death22
Investigating the neurotoxicity of environmental pollutants using zebrafish as a model organism: A review and recommendations for future work22
Amyotrophic lateral sclerosis and lead: A systematic update22
The uses of 3D human brain organoids for neurotoxicity evaluations: A review21
Effects of concentrated ambient ultrafine particulate matter on hallmarks of Alzheimer’s disease in the 3xTgAD mouse model20
Astragalin attenuates AlCl3/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation20
Exposure to PM2.5 induces neurotoxicity, mitochondrial dysfunction, oxidative stress and inflammation in human SH-SY5Y neuronal cells20
Fluoxetine-induced neurotoxicity at environmentally relevant concentrations in adult zebrafish Danio rerio19
Bisphenol-A inhibits mitochondrial biogenesis via impairment of GFER mediated mitochondrial protein import in the rat brain hippocampus19
Pregnancy exposure to carbon black nanoparticles induced neurobehavioral deficits that are associated with altered m6A modification in offspring19
TREM2 ameliorates anesthesia and surgery-induced cognitive impairment by regulating mitophagy and NLRP3 inflammasome in aged C57/BL6 mice19
Ameliorative effects of flavonoids and polyketides on the rotenone induced Drosophila model of Parkinson’s disease19
Effect of suvorexant on morphine tolerance and dependence in mice: Role of NMDA, AMPA, ERK and CREB proteins19
RETRACTED: Melatonin rescues the mice brain against cisplatin-induced neurodegeneration, an insight into antioxidant and anti-inflammatory effects18
Genkwanin suppresses MPP+-induced cytotoxicity by inhibiting TLR4/MyD88/NLRP3 inflammasome pathway in a cellular model of Parkinson’s disease18
Depression and anxiety in a manganese-exposed community18
Exposure to bisphenol A differentially impacts neurodevelopment and behavior in Drosophila melanogaster from distinct genetic backgrounds18
Edaravone attenuates cadmium-induced toxicity by inhibiting oxidative stress and inflammation in ICR mice17
Naringin attenuates Bisphenol-A mediated neurotoxicity in hypertensive rats by abrogation of cerebral nucleotide depletion, oxidative damage and neuroinflammation17
Galangin mitigates DOX-induced cognitive impairment in rats: Implication of NOX-1/Nrf-2/HMGB1/TLR4 and TNF-α/MAPKs/RIPK/MLKL/BDNF17
Fluoride affects memory by altering the transcriptional activity in the central nervous system of Lymnaea stagnalis17
Dihydropyrimidinone-derived selenoesters efficacy and safety in an in vivo model of Aβ aggregation17
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis17
Effects of endocrine disrupting chemicals on myelin development and diseases16
Mercury and neurochemical biomarkers in multiple brain regions of five Arctic marine mammals16
Biological determinants impact the neurovascular toxicity of nicotine and tobacco smoke: A pharmacokinetic and pharmacodynamics perspective16
Methylmercury chloride exposure aggravates proinflammatory mediators and Notch-1 signaling in CD14+ and CD40+ cells and is associated with imbalance of neuroimmune function in BTBR T+ Itpr3tf/J mice16
Early developmental exposure to bisphenol A and bisphenol S disrupts socio-cognitive function, isotocin equilibrium, and excitation-inhibition balance in developing zebrafish16
Cholecystokinin-8 attenuates methamphetamine-induced inflammatory activation of microglial cells through CCK2 receptor16
Fine particulate matter induces endoplasmic reticulum stress-mediated apoptosis in human SH-SY5Y cells16
Organophosphate insecticides disturb neuronal network development and function via non-AChE mediated mechanisms16
Selenium nanoparticles impart robust neuroprotection against deltamethrin-induced neurotoxicity in male rats by reversing behavioral alterations, oxidative damage, apoptosis, and neuronal loss16
Dietary fluoride intake during pregnancy and neurodevelopment in toddlers: A prospective study in the progress cohort16
Role of melatonin in TLR4-mediated inflammatory pathway in the MTPT-induced mouse model16
Remarkable migration propensity of dental pulp stem cells towards neurodegenerative milieu: An in vitro analysis16
Neuromelanin formation exacerbates HAA-induced mitochondrial toxicity and mitophagy impairments15
Zinc nanoparticles ameliorate oxidative stress and apoptosis induced by silver nanoparticles in the brain of male rats15
Comparison of neuropathology in rats following status epilepticus induced by diisopropylfluorophosphate and soman15
Lead (Pb) exposure exacerbates behavioral and immune abnormalities by upregulating Th17 and NF-κB-related signaling in BTBR T+ Itpr3tf/J autistic mouse model15
Paternal cannabis extract exposure in rats: Preconception timing effects on neurodevelopmental behavior in offspring15
In silico identification of the potential molecular mechanisms involved in protective effects of prolactin on motor and memory deficits induced by 1,2-Diacetylbenzene in young and old rats15
Dihydroactinidiolide regulates Nrf2/HO-1 expression and inhibits caspase-3/Bax pathway to protect SH-SY5Y human neuroblastoma cells from oxidative stress induced neuronal apoptosis15
Developmental Perfluorooctanesulfonic acid (PFOS) exposure as a potential risk factor for late-onset Alzheimer’s disease in CD-1 mice and SH-SY5Y cells15
Naringin enhances long-term potentiation and recovers learning and memory deficits of amyloid-beta induced Alzheimer’s disease-like behavioral rat model14
Cerebral concentration and toxicity of endocrine disrupting chemicals: The implication of blood-brain interfaces14
Gasdermin D-mediated microglial pyroptosis exacerbates neurotoxicity of aflatoxins B1 and M1 in mouse primary microglia and neuronal cultures14
Chlorpyrifos, permethrin and cyfluthrin effect on cell survival, permeability, and tight junction in an in-vitro model of the human blood-brain barrier (BBB)14
Edaravone attenuates H2O2 or glutamate-induced toxicity in hippocampal neurons and improves AlCl3/D-galactose induced cognitive impairment in mice14
Prenatal exposure to a mixture of organophosphate esters and intelligence among 8-year-old children of the HOME Study14
Cognitive effects of the GSK-3 inhibitor “lithium” in LPS/chronic mild stress rat model of depression: Hippocampal and cortical neuroinflammation and tauopathy13
The involvement of TRPV4 on the hypoxia-induced oxidative neurotoxicity and apoptosis in a neuronal cell line: Protective role of melatonin13
Evaluation of the neurotoxic effects of engineered nanomaterials in C57BL/6J mice in 28-day oral exposure studies13
Mercury in dental amalgam: a risk analysis13
Are ion channels potential therapeutic targets for Parkinson’s disease?13
Neuroprotective effects of dopamine D2 receptor agonist on neuroinflammatory injury in olfactory bulb neurons in vitro and in vivo in a mouse model of allergic rhinitis13
Protective effect of nanocurcumin against neurotoxicity induced by doxorubicin in rat’s brain13
Dose-related biphasic effect of the Parkinson’s disease neurotoxin MPTP, on the spread, accumulation, and toxicity of α-synuclein13
Paraquat induces redox imbalance and disrupts glutamate and energy metabolism in the hippocampus of prepubertal rats13
Developmental exposure to methylmercury and resultant muscle mercury accumulation and adult motor deficits in mice13
Resveratrol prevents haloperidol-induced mitochondria dysfunction through the induction of autophagy in SH-SY5Y cells13
Ursolic acid ameliorates amyloid β-induced pathological symptoms in Caenorhabditis elegans by activating the proteasome13
Cox regression model of prognostic factors for delayed neuropsychiatric sequelae in patients with acute carbon monoxide poisoning: A prospective observational study13
JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson’s disease: Mitochondrial protection and antioxidant properties12
Curcumin attenuates spatial memory impairment by anti-oxidative, anti-apoptosis, and anti-inflammatory mechanism against methamphetamine neurotoxicity in male Wistar rats: Histological and biochemical12
Vinpocetine prevents rotenone-induced Parkinson disease motor and non-motor symptoms through attenuation of oxidative stress, neuroinflammation and α-synuclein expressions in rats12
Xenobiotic transport and metabolism in the human brain12
JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats12
Neuroprotective effects of the CTK 01512-2 toxin against neurotoxicity induced by 3-nitropropionic acid in rats12
Neuroprotective effect of quercetin and nano-quercetin against cyclophosphamide-induced oxidative stress in the rat brain: Role of Nrf2/ HO-1/Keap-1 signaling pathway12
Effects of pramipexole on beta-amyloid1–42 memory deficits and evaluation of oxidative stress and mitochondrial function markers in the hippocampus of Wistar rat12
Prolonged fluoride exposure alters neurotransmission and oxidative stress in the zebrafish brain12
Sex differences in inflammatory cytokine levels following synthetic cathinone self-administration in rats12
Bisphenol a affects neurodevelopmental gene expression, cognitive function, and neuromuscular synaptic morphology in Drosophila melanogaster12
Rat developmental fluoride exposure affects retention memory, leads to a depressive-like behavior, and induces biochemical changes in offspring rat brains11
Biochanin A protects SH-SY5Y cells against isoflurane-induced neurotoxicity by suppressing oxidative stress and apoptosis11
Improvement of non-motor and motor behavioral alterations associated with Parkinson-like disease in Drosophila melanogaster: Comparative effects of treatments with hesperidin and L-dopa11
Comparative assessment of blood Metal/metalloid levels, clinical heterogeneity, and disease severity in amyotrophic lateral sclerosis patients11
Thiamethoxam evoked neural oxido-inflammatory stress in male rats through modulation of Nrf2/NF-kB/iNOS signaling and inflammatory cytokines: Neuroprotective effect of Silymarin11
RETRACTED: Tranilast ameliorated subchronic silver nanoparticles-induced cerebral toxicity in rats: Effect on TLR4/NLRP3 and Nrf-211
Role of amyloid beta (25−35) neurotoxicity in the ferroptosis and necroptosis as modalities of regulated cell death in Alzheimer's disease11
Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate11
Ferroptosis contributes to methylmercury-induced cytotoxicity in rat primary astrocytes and Buffalo rat liver cells11
General anesthesia activates the mitochondrial unfolded protein response and induces age-dependent, long-lasting changes in mitochondrial function in the developing brain10
Peripherally administered persistent organic pollutants distribute to the brain of developing chicken embryo in concentrations relevant for human exposure10
Nuclear accumulation of histone deacetylase 4 (HDAC4) by PP1-mediated dephosphorylation exerts neurotoxicity in Pb-exposed neural cells10
Shedding light on the toxicity of SARS-CoV-2-derived peptide in non-target COVID-19 organisms: A study involving inbred and outbred mice10
Low-level lead exposure during development differentially affects neurobehavioral responses in male and female mouse offspring: A longitudinal study10
Mitochondrial and transcriptome responses in rat dopaminergic neuronal cells following exposure to the insecticide fipronil10
Exposure to metal mixtures and neuropsychological functioning in middle childhood10
Effect of arsenic-containing hydrocarbon on the long-term potentiation at Schaffer Collateral-CA1 synapses from infantile male rat10
Associations of prenatal exposure to phthalates with measures of cognition in 7.5-month-old infants10
Age-related vulnerability to nigral dopaminergic degeneration in rats via Zn2+-permeable GluR2-lacking AMPA receptor activation10
Pharmacological evaluation of bromelain in mouse model of Alzheimer’s disease10
Distribution of Pb and Se in mouse brain following subchronic Pb exposure by using synchrotron X-ray fluorescence10
AMPA receptor contribution to methylmercury-mediated alteration of intracellular Ca2+ concentration in human induced pluripotent stem cell motor neurons10
Exposure of particulate matter (PM10) induces neurodevelopmental toxicity in zebrafish embryos10
Lead exposure in the home environment: An overview of risks from cottage industries in Africa10
Melatonin and zinc supplements with physical and mental activities subside neurodegeneration and hepatorenal injury induced by aluminum chloride in rats: Inclusion of GSK-3β-Wnt/β-catenin signaling pa9
Neurotoxicity assessment of QoI strobilurin fungicides azoxystrobin and trifloxystrobin in human SH-SY5Y neuroblastoma cells: Insights from lipidomics and mitochondrial bioenergetics9
Manganese-induced reactive oxygen species activate IκB kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro9
Positive regulation of the CREB phosphorylation via JNK-dependent pathway prevents antimony-induced neuronal apoptosis in PC12 cell and mice brain9
The benefits of fish intake: Results concerning prenatal mercury exposure and child outcomes from the ALSPAC prebirth cohort9
Novel benzodiazepine remimazolam tosylate delays neurodegeneration of aged mice via decreasing tau phosphorylation9
Jatamansinol from Nardostachys jatamansi (D.Don) DC. Protects Aβ42-Induced Neurotoxicity in Alzheimer's Disease Drosophila Model9
Vitamin A supplementation ameliorates motor incoordination via modulating RORα in the cerebellum in a valproic acid-treated rat autism model with vitamin A deficiency9
Environmental manganese exposure and cognitive control in a South African population9
Blood brain barrier as an interface for alcohol induced neurotoxicity during development9
SB332235, a CXCR2 antagonist, ameliorates thioacetamide-induced hepatic encephalopathy through modulation of the PI3K/AKT pathways in rats9
Developmental neurotoxicity of acrylamide and its metabolite glycidamide in a human mixed culture of neurons and astrocytes undergoing differentiation in concentrations relevant for human exposure9
Suicidality among South Brazilian tobacco growers9
Analysis of serum levels of organochlorine pesticides and related factors in Parkinson’s disease9
Teratogenic effects of maternal drug abuse on developing brain and underlying neurotransmitter mechanisms9
Cytotoxicity and transcriptome changes triggered by CuInS2/ZnS quantum dots in human glial cells9
Persistent proteomic changes in glutamatergic and GABAergic signaling in the amygdala of adolescent rats exposed to chlorpyrifos as juveniles9
Evaluation of chemical compounds that inhibit neurite outgrowth using GFP-labeled iPSC-derived human neurons9
Seizurogenic effect of perfluorooctane sulfonate in zebrafish larvae9
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