Clinical Therapeutics

Article	Citations
Phage Therapy in the Resistance Era: Where Do We Stand and Where Are We Going?	137
Antibiotic Stewardship in Food-producing Animals: Challenges, Progress, and Opportunities	98
Effect of Social Determinants of Health on Cognition and Risk of Alzheimer Disease and Related Dementias	86
Breastfeeding in a Global Context: Epidemiology, Impact, and Future Directions	62
Global Burden of Dry Age-Related Macular Degeneration: A Targeted Literature Review	57
Caregivers' Willingness to Accept Expedited Vaccine Research During the COVID-19 Pandemic: A Cross-sectional Survey	55
Real-World Evidence for Regulatory Decision-Making: Guidance From Around the World	49
A Narrative Review of Sex Differences in Eating Disorders: Is There a Biological Basis?	47
Maternal Psychological Distress and Lactation and Breastfeeding Outcomes: a Narrative Review	47
Safety, Virologic Efficacy, and Pharmacokinetics of CT-P59, a Neutralizing Monoclonal Antibody Against SARS-CoV-2 Spike Receptor-Binding Protein: Two Randomized, Placebo-Controlled, Phase I Studies in	42
Effects of Ivermectin in Patients With COVID-19: A Multicenter, Double-blind, Randomized, Controlled Clinical Trial	41
Modifiable Risk Factors in Alzheimer Disease and Related Dementias: A Review	39
Once-Daily SPN-812 200 and 400 mg in the treatment of ADHD in School-aged Children: A Phase III Randomized, Controlled Trial	39
Nonalcoholic Fatty Liver Disease: A Global Perspective	39
Current Therapeutic Approaches to Anorexia Nervosa: State of the Art	38
Eptinezumab for the Prevention of Episodic Migraine: Sustained Effect Through 1 Year of Treatment in the PROMISE-1 Study	35
Potential Therapeutic Effects of Sodium Glucose-linked Cotransporter 2 Inhibitors in Stroke	32
Prescribing in Type 2 Diabetes Patients With and Without Cardiovascular Disease History: A Descriptive Analysis in the UK CPRD	32
Corneal Confocal Microscopy: A Biomarker for Diabetic Peripheral Neuropathy	31
The Neurobiology of Binge-eating Disorder Compared with Obesity: Implications for Differential Therapeutics	31
The Role of Probiotics, Prebiotics and Synbiotics in Combating Multidrug-Resistant Organisms	30
State of the Art: The Therapeutic Approaches to Bulimia Nervosa	29
Anesthesia and the Developing Brain: A Review of Sevoflurane-induced Neurotoxicity in Pediatric Populations	29
Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study	29
Coronavirus 2019, Microthromboses, and Platelet Activating Factor	28

Paid Caregivers in the Community-based Dementia Care Team: Do Family Caregivers Benefit?	28
Consolidated Health Economic Evaluation Reporting Standards 2022 (CHEERS 2022) Statement: Updated Reporting Guidance for Health Economic Evaluations	27
Social Determinants of Breastfeeding in the United States	27
Clinical Practice Guideline for the Therapeutic Drug Monitoring of Voriconazole in Non-Asian and Asian Adult Patients: Consensus Review by the Japanese Society of Chemotherapy and the Japanese Society	25
Human Milk and Preterm Infant Brain Development: A Narrative Review	24
Early Use of Remdesivir and Risk of Disease Progression in Hospitalized Patients With Mild to Moderate COVID-19	24
Cardiac Autonomic Neuropathy in Type 1 and 2 Diabetes: Epidemiology, Pathophysiology, and Management	24
Real-World Data in the Postapproval Setting as Applied by the EMA and the US FDA	23
Psychotherapy and Medications for Eating Disorders: Better Together?	23
Celecoxib-tramadol co-crystal: A Randomized 4-Way Crossover Comparative Bioavailability Study	22
Therapy for Nonalcoholic Fatty Liver Disease: Current Options and Future Directions	22
Gestational Diabetes Mellitus Is Associated with Altered Abundance of Exosomal MicroRNAs in Human Milk	22
Cost-Effectiveness Analysis of Tisagenlecleucel for the Treatment of Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma in the United States	22
Vitamin D in the Prevention and Treatment of Diabetic Neuropathy	22
Treatment of Eating Disorders in Adults Versus Adolescents: Similarities and Differences	21
Risk of Thromboembolic Events and Associated Risk Factors, Including Treatments, in Patients with Immune-mediated Diseases	21
Novel and Emerging Electrophysiological Biomarkers of Diabetic Neuropathy and Painful Diabetic Neuropathy	20
Serum Ammonia in Cirrhosis: Clinical Impact of Hyperammonemia, Utility of Testing, and National Testing Trends	19
Pharmacokinetics of Direct Oral Anticoagulants in Patients With Atrial Fibrillation and Extreme Obesity	19
Global Trends in Atherosclerotic Cardiovascular Disease	19
Mesenchymal Stem Cells in Cardiac Repair: Effects on Myocytes, Vasculature, and Fibroblasts	18
A Systematic Review and Meta-analysis of Isoniazid Pharmacokinetics in Healthy Volunteers and Patients with Tuberculosis	18
Economic Burden of Checkpoint Inhibitor Immunotherapy for the Treatment of Non–Small Cell Lung Cancer in US Clinical Practice	18
Phage Therapy for Diabetic Foot Infection: A Case Series	18
Tezepelumab Pharmacokinetics, Safety, and Tolerability After Administration via Vial-and-syringe, Accessorized Prefilled Syringe, or Autoinjector: A Randomized Trial in Healthy Volunteers	18
Regulatory Agilities in the Time of COVID-19: Overview, Trends, and Opportunities	18
Safety and Efficacy of Mirogabalin for Peripheral Neuropathic Pain: Pooled Analysis of Two Pivotal Phase III Studies	18
Effect of Probiotic, Prebiotic, and Synbiotic Supplementation on Cardiometabolic and Oxidative Stress Parameters in Patients With Chronic Kidney Disease: A Systematic Review and Meta-analysis	18
Pharmacokinetics, Pharmacodynamics, and Tolerability of Olpasiran in Healthy Japanese and Non-Japanese Participants: Results from a Phase I, Single-dose, Open-label Study	17
Citicoline as Adjuvant Therapy in Parkinson's Disease: A Systematic Review	17
A Higher Dose of Dasatinib May Increase the Possibility of Crossing the Blood–brain Barrier in the Treatment of Patients With Philadelphia Chromosome–positive Acute Lymphoblastic Leukemia	17
Comparative Efficacy of Acalabrutinib in Frontline Treatment of Chronic Lymphocytic Leukemia: A Systematic Review and Network Meta-analysis	16
Rolling Reviews During COVID-19: The European Union Experience in a Global Context	16
Target Populations and Treatment Cost for Bempedoic Acid and PCSK9 Inhibitors: A Simulation Study in a Contemporary CAD Cohort	16
Behavioral Economics and Ambulatory Antibiotic Stewardship: A Narrative Review	16
Understanding Racial Disparities of Preterm Birth Through the Placenta	15
Prevalence of Chronic Kidney Disease in Type 2 Diabetes: The Canadian REgistry of Chronic Kidney Disease in Diabetes Outcomes (CREDO) Study	15
Sex- or Gender-specific Differences in the Clinical Presentation, Outcome, and Treatment of SARS-CoV-2	15
Launch Delay of New Drugs in China and Effect on Patients’ Health	15
Nutrition as Therapy in Liver Disease	15
Emerging and Established Therapeutic Approaches for Nonalcoholic Fatty Liver Disease	15
Effects of Baseline Left Ventricular Hypertrophy and Decreased Renal Function on Cardiovascular and Renal Outcomes in Patients with Fabry Disease Treated with Agalsidase Alfa: A Fabry Outcome Survey S	15
Artificial Intelligence in Pharmacovigilance: Scoping Points to Consider	15
Population Pharmacokinetics and Exposure–Response Analyses of Ustekinumab in Patients With Moderately to Severely Active Crohn's Disease	14
The Cardiac Injury Immune Response as a Target for Regenerative and Cellular Therapies	14
Use of Silica Nanoparticles for Drug Delivery in Cardiovascular Disease	14
Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review	14
Effect of Pegylated Interferon Plus Tenofovir Combination on Higher Hepatitis B Surface Antigen Loss in Treatment-naive Patients With Hepatitis B e Antigen -positive Chronic Hepatitis B: A Real-world	14
Inhibition of Diacylglycerol Acyltransferase 2 Versus Diacylglycerol Acyltransferase 1: Potential Therapeutic Implications of Pharmacology	14
Real-world Effectiveness of Mepolizumab in Severe Eosinophilic Asthma: A Systematic Review and Meta-analysis	14

Health-Related Quality of Life Among Patients With HR+/HER2– Early Breast Cancer	14
Placental Impact of Dietary Supplements: More Than Micronutrients	13
The COVID-19 mRNA Vaccines and the Pandemic: Do They Represent the Beginning of the End or the End of the Beginning?	13
Design and Protocol of the Renal Anhydramnios Fetal Therapy (RAFT) Trial	13
Machine Learning as a Precision-Medicine Approach to Prescribing COVID-19 Pharmacotherapy with Remdesivir or Corticosteroids	13
Effect of Glucagon-like Peptide-1 Receptor Agonists on Prognosis of Heart Failure and Cardiac Function: A Systematic Review and Meta-analysis of Randomized Controlled Trials	13
Prevalence of Potential Drug-drug Interactions With Ritonavir-containing COVID-19 Therapy in the United States: An Analysis of the National Health and Nutrition Examination Survey	13
Food as Medicine for Obesity Treatment and Management	13
Efficacy and Usability of Intranasal Glucagon for the Management of Hypoglycemia in Patients With Diabetes: A Systematic Review	13
Circulating IRAPe, Irisin, and IL-34 in Relation to Insulin Resistance in Patients With Type 2 Diabetes	13
Reinforcement Learning Methods in Public Health	13
Efficacy and Safety of the Remimazolam-Alfentanil Combination for Sedation During Gastroscopy: A Randomized, Double-blind, Single-center Controlled Trial	12
Real-World Effectiveness of Once-Weekly Semaglutide From a US Commercially Insured and Medicare Advantage Population	12
Effect of ABCB1 3435C>T Genetic Polymorphism on Pharmacokinetic Variables of Tacrolimus in Adult Renal Transplant Recipients: A Systematic Review and Meta-analysis	12
Assessment of Cardiotoxicity With Stem Cell-based Strategies	12
Tolerability and Safety of Lasmiditan Treatment in Elderly Patients With Migraine: Post Hoc Analyses From Randomized Studies	12
Association Between the Overall Risk of Prostate Cancer and Use of Calcium Channel Blockers: A Systematic Review and Meta-analysis	12
Applications of Novel and Nanostructured Drug Delivery Systems for the Treatment of Oral Cavity Diseases	12
Treatment Patterns and Outcomes in Triple-Class Exposed Patients With Relapsed and Refractory Multiple Myeloma: Findings From the Multinational ITEMISE Study	12
A Phase I, Open-label, Randomized, 2-Way Crossover Study to Evaluate the Relative Bioavailability of Intranasal and Oral Varenicline	12
Pharmacokinetic and Glucodynamic Responses of Ultra Rapid Lispro vs Lispro Across a Clinically Relevant Range of Subcutaneous Doses in Healthy Subjects	12
Emerging Treatment Strategies for Impetigo in Endemic and Nonendemic Settings: A Systematic Review	11
Use of the Electronic Health Record to Optimize Antimicrobial Prescribing	11
The Promise of PCSK9 and Lipoprotein(a) as Targets for Gene Silencing Therapies	11
Pharmacokinetic and Pharmacodynamic Interactions Between Henagliflozin, a Novel Selective SGLT-2 Inhibitor, and Warfarin in Healthy Chinese Subjects	11
Cost-effectiveness of Osimertinib vs Docetaxel-bevacizumab in Third-line Treatment in EGFR T790M Resistance Mutation Advanced Non–Small Cell Lung Cancer in China	11
Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Single Oral Dose of Tegoprazan	11
Effect of the Phosphate Binders Sevelamer Carbonate and Calcium Acetate on the Pharmacokinetics of Roxadustat After Concomitant or Time-separated Administration in Healthy Individuals	11
The Influence of Obesity and Associated Fatty Acids on Placental Inflammation	11
Dynamic Regulatory Assessment: evolving the European Regulatory Framework for the Benefit of Patients and Public Health—an EFPIA View	10
Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Adm	10
Resistance Training as Treatment for Sarcopenia: Examining Sex-Related Differences in Physiology and Response	10
Impact of Baseline Characteristics on the Efficacy and Safety of Eptinezumab in Patients With Migraine: Subgroup Analyses of PROMISE-1 and PROMISE-2	10
Artificial Intelligence and Data Mining for the Pharmacovigilance of Drug–Drug Interactions	10
Value of Growth/Differentiation Factor 15 in Diagnosis and the Evaluation of Chemotherapeutic Response in Lung Cancer	10
A Comparison of Coagulation Function in Patients Receiving Aspirin and Cefoperazone-Sulbactam With and Without Vitamin K1: A Retrospective, Observational Study	10
Noninvasive Evaluation for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis	10
Advanced Therapies and Regulatory Framework in Different Areas of the Globe: Past, Present, and Future	10
Gene and Cell Therapy for Cardiac Arrhythmias	10
Evaluation of Pharmacokinetic Interactions Between the New SGLT2 Inhibitor SHR3824 and Valsartan in Healthy Chinese Volunteers	10
Cost-effectiveness of Oral Versus Intravenous Ibuprofen Therapy in Preterm Infants With Patent Ductus Arteriosus in the Neonatal Intensive Care Setting: A Cohort-based Study	10
Effects of Fixed-dose Combination of Low-intensity Rosuvastatin and Ezetimibe Versus Moderate-intensity Rosuvastatin Monotherapy on Lipid Profiles in Patients With Hypercholesterolemia: A Randomized,	9
Effect of Food on the Pharmacokinetic and Pharmacodynamic Profiles of Hetrombopag in Healthy Volunteers	9
Comparison of Continuous Infusion of Epinephrine and Phenylephrine on Hemodynamics During Spinal Anesthesia for Cesarean Delivery: A Randomized Controlled Trial	9
Relationship Between Vitamin D Level and Mortality in Adults With Psoriasis: A Retrospective Cohort Study of NHANES Data	9
Effect of Sleeve Gastrectomy on Buprenorphine Pharmacokinetics: A Planned Case Observation	9
Sex Differences in Physical Activity and Incident Stroke: A Systematic Review	9
Therapeutic Target Attainment of 3-Hour Extended Infusion of Meropenem in Patients With Septic Burns	9
Association Between the CYP2C9 Genotype and Hypoglycemia Among Patients With Type 2 Diabetes Receiving Sulfonylurea Treatment: A Meta-analysis	9
Targeting the Dysfunctional Placenta to Improve Pregnancy Outcomes Based on Lessons Learned in Cancer	9
Effects of Calcium and Vitamin D Co-supplementation on the Lipid Profile: A Systematic Review and Meta-analysis	9
Diabetic Foot Ulcers and Cardiac Autonomic Neuropathy	9
Robust Cardiac Regeneration: Fulfilling the Promise of Cardiac Cell Therapy	9
Comorbidities in Psoriatic Arthritis: A Narrative Review	9
Efficacy, Safety, and Tolerability of a Novel Cyclosporine, a Formulation for Dry Eye Disease: A Multicenter Phase II Clinical Study	9
Strong Pharmacokinetic Drug-Drug Interactions With Drugs Approved by the US Food and Drug Administration in 2021: Mechanisms and Clinical Implications	9
Differential Expression of Rab5 and Rab7 Small GTPase Proteins in Placental Tissues From Pregnancies Affected by Maternal Coronavirus Disease 2019	9
Exercise and the Female Heart	8
Cost-Effectiveness of Baricitinib Compared With Standard of Care: A Modeling Study in Hospitalized Patients With COVID-19 in the United States	8
The Effects of Folic Acid Supplementation on Pro-inflammatory Mediators: a Systematic Review and Dose–Response Meta‐Analysis of Randomized Controlled Trials	8
Effectiveness, Safety, and Adherence to Treatment of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors in Real Practice	8
Willingness to Accept Expedited COVID-19 Vaccine Research for Children Aged <12 Years After Adult Vaccine Approval	8
Real-world Treatment Patterns and Clinical Outcomes Associated With Palbociclib Combination Therapy: A Multinational, Pooled Analysis From the Ibrance Real World Insights Study	8
Economic Evaluation of New Oral Anticoagulants in Prevention of Venous Thrombosis Following Joint Replacement Surgery: A Systematic Review	8
Pharmacokinetics and safety of capmatinib with food in patients with MET-dysregulated advanced solid tumors	8
Cost-effectiveness of Capecitabine + Irinotecan Versus Leucovorin + Fluorouracil + Irinotecan in the Second-line Treatment of Metastatic Colorectal Cancer in China	8
Results of two Phase 1, Randomized, Double-blind, Placebo-controlled, Studies (Ascending Single-dose and Multiple-dose Studies) to Determine the Safety, Tolerability, and Pharmacokinetics of Orally Ad	8
Advances in the Epidemiology, Diagnosis, and Management of Pediatric Fatty Liver Disease	8
Pharmacokinetics of FT218, a Once-Nightly Sodium Oxybate Formulation in Healthy Adults	8
Lifetime Cost-effectiveness of Oral Semaglutide Versus Dulaglutide and Liraglutide in Patients With Type 2 Diabetes Inadequately Controlled With Oral Antidiabetics	8
Influence of Genetic Polymorphisms on the Response to Tramadol, Ibuprofen, and the Combination in Patients With Moderate to Severe Pain After Dental Surgery	8
Assessing the Cost-effectiveness of a Hypothetical Disease-modifying Therapy With Limited Duration for the Treatment of Early Symptomatic Alzheimer Disease	8
Edaravone for Acute Ischemic Stroke: A Systematic Review and Meta-analysis	8
Effect of Antifibrotic Therapy on Survival in Patients With Idiopathic Pulmonary Fibrosis	8
Therapeutic Efficacy of Piperazine Ferulate Combined With Irbesartan in Diabetic Nephropathy: A Systematic Review and Meta-analysis	8
Genetic Studies Investigating Susceptibility to Psoriatic Arthritis: A Narrative Review	8
Exenatide Once Weekly: Effectiveness, Tolerability, and Discontinuation Predictors in a Real-world Setting	8
Dipeptidyl Peptidase-4 Inhibitors, Glucagon-like Peptide-1 Receptor Agonists, and Sodium-Glucose Cotransporter-2 Inhibitors and COVID-19 Outcomes	7
Characteristics of Patients with Hereditary Transthyretin Amyloidosis and an Evaluation of the Safety of Tafamidis Meglumine in Japan: An Interim Analysis of an All-case Postmarketing Surveillance	7
Pharmacokinetic Interactions between Tegoprazan and Metronidazole/Tetracycline/Bismuth and Safety Assessment in Healthy Korean Male Subjects	7

The Impact of Highly Effective Cystic Fibrosis Transmembrane Conductance Regulator Modulators on the Health of Female Subjects With Cystic Fibrosis	7
Beyond Influenza Vaccination: Expanding Infrastructure for Hospital-based Pediatric COVID-19 Vaccine Delivery	7
Efficacy of Urate–Lowering Therapy in Patients With Chronic Kidney Disease: A Network Meta-Analysis of Randomized Controlled Trials	7
Efficacy and Tolerability of Insulin Degludec Versus Other Long-acting Basal Insulin Analogues in the Treatment of Type 1 and Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis	7
The Impact of Diabetes and Glucose-Lowering Therapies on Hepatocellular Carcinoma Incidence and Overall Survival	7
The 5% Lidocaine Patch for Decreasing Postoperative Pain and Rescue Opioid Use in Sternotomy: A Prospective, Randomized, Double-blind Trial	7
Greater Adherence and Persistence with Injectable Dulaglutide Compared with Injectable Semaglutide at 1-Year Follow-up: Data from US Clinical Practice	7
Clinical Performance and Impact of Accelerate Pheno for Gram-negative Bacteremia in Hospitalized Children	7
Pooled Analysis of Gastric Emptying in Patients With Obesity: Implications for Oral Absorption Projection	7
The Next Set of COVID-19 Vaccines: Leveraging New Development Platforms to Increase Access for More People Around the World	7
Pharmacokinetics of Efavirenz 600 mg Once Daily During Pregnancy and Post Partum in Ghanaian Women Living With HIV	7
Rifaximin Treatment for Individual and Multiple Symptoms of Irritable Bowel Syndrome With Diarrhea: An Analysis Using New End Points	7
Apolipoprotein B Displays Superior Predictive Value Than Other Lipids for Long-Term Prognosis in Coronary Atherosclerosis Patients and Particular Subpopulations: A Retrospective Study	7
Patient and Caregiver Health State Utilities in Lennox-Gastaut Syndrome and Dravet Syndrome	7
Effects of the COVID-19 Pandemic on Spontaneous Reporting: Global and National Time-series Analyses	7
Efficacy and Safety of Fenofibrate-Statin Combination Therapy in Patients With Inadequately Controlled Triglyceride Levels Despite Previous Statin Monotherapy: A Multicenter, Randomized, Double-blind,	7
Clinical Outcomes Associated With the Use of Anticoagulant and Antiplatelet Agents in Patients Undergoing Treatment for Infective Endocarditis: A Pilot Study	7
Industry Sponsor Influence in Clinical Trial Reporting in Canada: A Qualitative Interview Study	7
Real-World Anticoagulant Use and Incidence of Venous Thromboembolism and Major Bleeding in Children	7
Efficacy and Safety of PCSK9 Monoclonal Antibodies in Patients With Diabetes	7
Efficacy and Tolerability of Ezetimibe/Atorvastatin Fixed-dose Combination Versus Atorvastatin Monotherapy in Hypercholesterolemia: A Phase III, Randomized, Active-controlled Study in Chinese Patients	7
A Critical Appraisal of the Effects of Anesthetics on Immune-system Modulation in Critically Ill Patients With COVID-19	7
Safety and Efficacy of Pitavastatin in Patients With Impaired Fasting Glucose and Hyperlipidemia: A Randomized, Open-labeled, Multicentered, Phase IV Study	7
Characteristics of Real-world Commercially Insured Patients With Treatment-resistant Depression Initiated on Esketamine Nasal Spray or Conventional Therapies in the United States	7
Pharmacologic Treatment Strategies in Psoriatic Arthritis	6
Impact of Influenza Infection Among Adult and Pediatric Populations With Hematologic Malignancy and Hematopoietic Stem Cell Transplant: A Systematic Review and Meta-Analysis	6
Enhancing Risk Stratification on Coronary Computed Tomography Angiography: The Role of Artificial Intelligence	6
In Vitro and Clinical Pharmacokinetic Studies of the Effects of Iron-containing Agents on Vadadustat, an Oral Hypoxia-inducible Factor–Prolyl Hydroxylase Inhibitor	6
Current and Emerging Biomarkers and Imaging Modalities for Nonalcoholic Fatty Liver Disease: Clinical and Research Applications	6
Drug–Drug Interactions of the Nonsteroidal Mineralocorticoid Receptor Antagonist Apararenone With Midazolam, Warfarin, and Digoxin: A Phase 1 Studies in Healthy Volunteers	6
Reduced Mortality After Oral Polio Vaccination and Increased Mortality After Diphtheria-tetanus-pertussis Vaccination in Children in a Low-income Setting	6
Bempedoic Acid: A New Tool in the Battle Against Hyperlipidemia	6
Efficacy and Safety of Single-dose OC-02 (Simpinicline Solution) Nasal Spray on Signs and Symptoms of Dry Eye Disease: The PEARL Phase II Randomized Trial	6
Effects of Glucocorticoids on Postoperative Delirium in Adult Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-analysis	6
The Health Care Resource Utilization and Costs Among Patients With Type 2 Diabetes and Either Cardiovascular Disease or Cardiovascular Risk Factors An Analysis of a US Health Insurance Database	6
History of Cannabis Regulation and Medicinal Therapeutics: It's Complicated	6
Late-stage Product Development and Approvals by Biotechnology Companies After Initial Public Offering, 1997–2016	6
New Targets in Atherosclerosis: Vascular Smooth Muscle Cell Plasticity and Macrophage Polarity	6
A Multicenter, Randomized, Double-blind, Active-controlled, Factorial Design, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy of Pitavastatin and Ezetimibe Versus M	6
Efficacy and Tolerability of Pitavastatin Versus Pitavastatin/Fenofibrate in High-risk Korean Patients with Mixed Dyslipidemia: A Multicenter, Randomized, Double-blinded, Parallel, Therapeutic Confirm	6
Comorbidities, Age, and Polypharmacy Limit the Use by US Older Adults with Nocturia of the Only FDA-approved Drugs for the Symptom	6
Electronic Health Record Network Research in Infectious Diseases	6
The Effect of Raloxifene Treatment on Lipid Profile in Elderly Individuals: A Systematic Review and Meta-analysis of Randomized Clinical Trials	6
Clinical Benefits and Cost-Effectiveness of Moxifloxacin as Initial Treatment for Community-Acquired Pneumonia: A Meta-Analysis and Economic Evaluation	6
Effects of the COVID-19 Pandemic on Pharmacovigilance Strategy, Systems, and Processes of Large, Medium, and Small Companies: An Industry Survey	6
Early Initiation of Evolocumab Treatment in Chinese Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention	6
Importance of Time Point–Specific Indirect Treatment Comparisons of Osteoporosis Treatments: A Systematic Literature Review and Network Meta-Analyses	6
Therapeutic Effect and Safety of Tripterygium Glycosides Combined With Western Medicine on Type 2 Diabetic Kidney Disease: A Meta-Analysis	6
Efficacy of Warfarin Therapy Guided by Pharmacogenetics: A Real-world Investigation Among Han Taiwanese	5
Impact of SLCO4C1 Genotypes, Creatinine, and Spironolactone on Digoxin Population Pharmacokinetic Variables in Patients With Cardiac Insufficiency	5
A Systematic Review of Medical Cannabinoids Dosing in Human	5
Dulaglutide Shows Sustained Reduction in Glycosylated Hemoglobin Values: 2-Year US Real-world Study Results	5
Treatment Patterns and Relapses Among Newly Treated Multiple Sclerosis Patients From a Retrospective Claims Analysis	5
Topical Clascoterone: The First Novel Agent for Acne Vulgaris in 40 Years	5
Review of FDA Amendments Act Section 921 Experience in Posting Data-mining Results from the FAERS Database	5
Cost-effectiveness Analysis of Dienogest Compared With Gonadotropin-Releasing Hormone Agonist After Conservative Surgery for Endometriosis in China	5
SGLT2 Inhibitors to Slow Chronic Kidney Disease Progression: A Review	5
An Automation System Equivalent to the Douglas Bag Technique Enables Continuous and Repeat Metabolic Measurements in Patients Undergoing Mechanical Ventilation	5
Dose Optimization of Vancomycin Using a Mechanism-based Exposure–Response Model in Pediatric Infectious Disease Patients	5
Immunogenicity and Safety of SpikoGen, an Adjuvanted Recombinant SARS-CoV-2 Spike Protein, as a Heterologous Third Booster Dose in Kidney Transplant Patients: A Single-arm Clinical Trial	5
Intra-Articular Injection of a Novel DVS Cross-Linked Hyaluronic Acid Manufactured by Biological Fermentation (YYD302) in Patients With Knee Osteoarthritis: A Double-Blind, Randomized, Multicenter, No	5
Pharmacoeconomic Evaluation of Erlotinib for the Treatment of Pancreatic Cancer	5
Cinnamon and Aspirin for Mild Ischemic Stroke or Transient Ischemic Attack: A Pilot Trial	5
Influence of COVID-19 on the Pharmacovigilance Workforce of the Future	5
Impact of a Clinical Decision Support System on Inappropriate Prescription of Glucose-lowering Agents for Patients With Renal Insufficiency in an Ambulatory Care Setting	5
Meta-analysis of the Efficacy and Tolerability of Immune Checkpoint Inhibitors Combined With Chemotherapy in First-line Treatment of Small Cell Lung Cancer	5
Efficacy of Intravenous Immunoglobulin Therapy for Patients With Sepsis and Low Immunoglobulin G Levels: A Single-Center Retrospective Study	5
Diet in Benign Colonic Disorders: A Narrative Review	5
Survey of Health Care Provider Understanding of Gene Therapy Research for Inherited Metabolic Disorders	5
Quantifying the Burden of Hyperphagia in Prader-Willi Syndrome Using Quality-Adjusted Life-years	5
Pharmacokinetic Comparability of Risankizumab Formulations in Prefilled Syringe and Auto-injector for Subcutaneous Injection	5
Real-World Characteristics and Treatment Patterns of Patients With Insomnia Prescribed Trazodone in the United States	5
Effects of Ivabradine on Cardiac Remodeling in Patients With Stable Symptomatic Heart Failure: A Systematic Review and Meta-analysis	5
Management of Primary Hyperparathyroidism With Severe Hypercalcemia During the COVID-19 Pandemic	5
Treatment Patterns Among Patients With Mantle Cell Lymphoma and Comparison of Healthcare Resource Utilization and Costs Among Relapsed/Refractory Patients Treated With Ibrutinib or Chemoimmunotherapy:	5
Self-reported Medicinal Cannabis Use as an Alternative to Prescription and Over-the-counter Medication Use Among US Military Veterans	5
Lessons from an Experiential Approach to Patient Community Engagement in Rare Disease	5
Sex-Based Differences in Peak Exercise Blood Pressure Indexed to Oxygen Consumption Among Competitive Athletes	5
Challenges in the Management of Psoriatic Arthritis in Latin America: A Systematic Review	5
Efficacy and Tolerability of Cyproheptadine in Poor Appetite: A Multicenter, Randomized, Double-blind, Placebo-controlled Study	5
Does Omega-3 Fatty Acid Supplementation Have Favorable Effects on the Lipid Profile in Postmenopausal Women? A Systematic Review and Dose–response Meta-analysis of Randomized Controlled Trials	5
Real-world impact of mepolizumab in patients with life-threatening asthma: US insurance claims database analysis	5
The Impact of Cannabis Use on Adolescent Neurodevelopment and Clinical Outcomes Amidst Changing State Policies	5
Interindividual Variability in the Pharmacodynamic and Pharmacokinetic Characteristics of Recombinant Human Insulin and Insulin Aspart	5
Predictors of Postoperative Nausea and Vomiting After Same-day Surgery: A Retrospective Study	5
Glycerol Infusion Versus Mannitol for Cerebral Edema: A Systematic Review and Meta-analysis	5
Nine Insights From 10 Years of Legal Cannabis for Nonmedical Purposes	5
A Research Agenda to Inform Cannabis Regulation: How Science Can Shape Policy	5
Exploration and Ethical Analysis of Open-label Pediatric Vaccine Trials in a Pandemic	5
Lipids, Lipid-Lowering Therapy, and Neuropathy: A Narrative Review	5
Projecting the Long-term Clinical Value of Mavacamten for the Treatment of Obstructive Hypertrophic Cardiomyopathy in the United States: An Assessment of Net Health Benefit	5
Melatonin: Translation of Ongoing Studies Into Possible Therapeutic Applications Outside Sleep Disorders	5
Antipsychotic Adherence, Resource Use, and Costs Before and After the Initiation of Once-monthly Paliperidone Palmitate Therapy Among Medicaid Beneficiaries With Prior Schizophrenia Relapse	5
Short-term Effects of Alfacalcidol on Hospital Length of Stay in Patients Undergoing Valve Replacement Surgery: A Randomized Clinical Trial	5
A Systematic Review of Systematic Reviews and a Pooled Meta-Analysis on Complementary and Integrative Medicine for Improving Cancer-Related Fatigue	5