Drug and Chemical Toxicology

Papers
(The TQCC of Drug and Chemical Toxicology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Chemical characterization of tobacco-free “modern” oral nicotine pouches and their position on the toxicant and risk continuums54
Rifampicin decreases neuroinflammation to maintain mitochondrial function and calcium homeostasis in rotenone-treated zebrafish22
Ameliorative effect of gallic acid on cisplatin-induced ovarian toxicity in rats20
Linalool exhibits therapeutic and protective effects in a rat model of doxorubicin-induced kidney injury by modulating oxidative stress20
Hepatoprotective effect of Ginkgo biloba extract against methotrexate-induced hepatotoxicity via targeting STAT3/miRNA-21 axis19
Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats16
Acrylamide induces intrinsic apoptosis and inhibits protective autophagy via the ROS mediated mitochondrial dysfunction pathway in U87-MG cells16
Melatonin modulates copper-induced anxiety-like, depression-like and memory impairments by acting on hippocampal oxidative stress in rat15
The comparison of the effect of Origanum vulgare L. extract and vitamin C on the gentamycin-induced nephrotoxicity in rats15
The outbreak of methanol intoxication during COVID-19 pandemic: prevalence of brain lesions and its predisposing factors14
Glabridin attenuates paracetamol-induced liver injury in mice via CYP2E1-mediated inhibition of oxidative stress13
Effect of carnosic acid on acrylamide induced neurotoxicity: in vivo and in vitro experiments13
Linalool reverses benzene-induced cytotoxicity, oxidative stress and lysosomal/mitochondrial damages in human lymphocytes13
Borassus flabellifer haustorium extract prevents pro-oxidant mediated cell death and LPS-induced inflammation13
L-Carnitine alleviates hepatic and renal mitochondrial-dependent apoptotic progression induced by letrozole in female rats through modulation of Nrf-2, Cyt c and CASP-3 signaling13
A comparison of cell death mechanisms of antioxidants, butylated hydroxyanisole and butylated hydroxytoluene13
Role of aluminum exposure on Alzheimer’s disease and related glycogen synthase kinase pathway13
Neurotoxicity of poly(propylene imine) glycodendrimers13
Ellagic acid alleviates clozapine‑induced oxidative stress and mitochondrial dysfunction in cardiomyocytes12
Morphine attenuates neurotoxic effects of MPTP in zebrafish embryos by regulating oxidant/antioxidant balance and acetylcholinesterase activity12
The effect of sulfamethoxazole on oxidative stress indices in zebrafish (Danio rerio)11
Effects of acrylamide on protein degradation pathways in human liver-derived cells and the efficacy ofN-acetylcysteine and curcumin11
The protective effects of vitamins A, C, and E on zinc oxide nanoparticles (ZnO NPs)-induced liver oxidative stress in male Wistar rats11
Lipid-lowering, anti-inflammatory, and hepatoprotective effects of isorhamnetin on acetaminophen-induced hepatotoxicity in mice11
Effects of burnt tire-ash on Na+/K+, Ca2+-ATPase, serum immunoglobulin and brain acetylcholinesterase activities in clarias gariepinus (Burchell, 1822)11
l -Theanine ameliorates motor deficit, mitochondrial dysfunction, and neurodegeneration against chronic tramadol induced rats model of Parkinson’s disease11
Gallic acid ameliorates busulfan-induced testicular toxicity and damage in mature rats10
The impact of filtered water-pipe smoke on healthy versus cancer cells and their neurodegenerative role on AMPA receptor10
Neurotoxic responses of rainbow trout ( Oncorhynchus mykiss ) exposed to fipronil: multi-biomarker approach to illuminate the mechanism in brain10
Effects of ellagic acid in the testes of streptozotocin induced diabetic rats10
Microplastic-induced oxidative stress response in turbot and potential intake by humans10
Investigation of the genotoxic effects of patent blue V (E131) in human peripheral lymphocytes and in silico molecular docking10
Therapeutic effects of thymoquinone or capsaicin on acrylamide-induced reproductive toxicity in rats mediated by their effect on oxidative stress, inflammation, and tight junction integrity9
Toxicological effects of the Morinda citrifolia L. fruit extract on maternal reproduction and fetal development in rats9
Antiandrogen enzalutamide induced genetic, cellular, and hepatic damages: amelioration by triterpene Lupeol9
Cytogenetic effects of antidiabetic drug metformin9
Cocoyam ( Colocasia esculenta ) modulates some parameters of testosterone propionate-induced rat model of benign prostatic hyperplasia9
Evaluation of the toxicological effects of favipiravir (T-705) on liver and kidney in rats: biochemical and histopathological approach9
Verbascoside inhibits paraquate-induced pulmonary toxicity via modulating oxidative stress, inflammation, apoptosis and DNA damage in A549 cell9
The role of ginger’s extract and N-acetylcysteine against docetaxel-induced oxidative stress and genetic disorder9
Salvianolic acid A suppresses CCl4-induced liver fibrosis through regulating the Nrf2/HO-1, NF-κB/IκBα, p38 MAPK, and JAK1/STAT3 signaling pathways9
Enhanced fluorescent sensing probe via PbS quantum dots functionalized with gelatin for sensitive determination of toxic bentazon in water samples9
Attenuation of methotrexate induced hepatotoxicity by epigallocatechin 3-gallate9
The protective effect of herniarin on genotoxicity and apoptosis induced by cisplatin in bone marrow cells of rats9
Borassus flabellifer Linn haustorium methanol extract mitigates fluoride-induced apoptosis by enhancing Nrf2/Haeme oxygenase 1 –dependent glutathione metabolism in intestinal epithe8
Protective effects of resveratrol and avocado oil against paracetamol-induced hepatotoxicity in rats8
Involvement of oxidative stress and toll-like receptor-4 signaling pathways in gentamicin-induced nephrotoxicity in male Sprague Dawley rats8
Trends of acute drug and chemical toxicities in adults and adolescents in Tehran, Iran between 2012 and 2018: a retrospective chart review8
Preventive treatment with sodium para-aminosalicylic acid inhibits manganese-induced apoptosis and inflammation via the MAPK pathway in rat thalamus8
Tissue-specific toxicity of clothianidin on rainbow trout (Oncorhynchus mykiss)8
Morel mushroom, Morchella from Kashmir Himalaya: a potential source of therapeutically useful bioactives that possess free radical scavenging, anti-inflammatory, and art8
Subacute oral toxicology and toxicokinetics of pterostilbene, a novel Top1/Tdp1 inhibiting anti-tumor reagent8
In silico QSAR modeling to predict the safe use of antibiotics during pregnancy8
Quercetin alleviates styrene oxide-induced cytotoxicity in cortical neuronsin vitrovia modulation of oxidative stress and apoptosis8
Protective effects ofp-coumaric acid against gentamicin-induced nephrotoxicity in rats8
Immunotoxic effects of force-fed ethephon on model organism Galleria mellonella (Lepidoptera: Pyralidae)8
Toxic and bioaccumulative effects of zinc nanoparticle exposure to goldfish, Carassius auratus (Linnaeus, 1758)7
Nano-titanium nitride causes developmental toxicity in zebrafish through oxidative stress7
Psoralen induces liver injuries through endoplasmic reticulum stress signaling in female mice7
MicroRNA as an early diagnostic biomarker for contrast-induced acute kidney injury7
Antioxidant, antinociceptive, anti-inflammatory, and hepatoprotective activities of pentacyclic triterpenes isolated from Ziziphus oxyphylla Edgew7
Alpha-mangostin attenuates the apoptotic pathway of abamectin in the fetal rats’ brain by targeting pro-oxidant stimulus, catecholaminergic neurotransmitters, and transcriptional regulation of reelin 7
Acute organophosphate and carbamate pesticide poisonings – a five-year survey from the National Poison Control Center Of Serbia7
PM2.5from diesel exhaust attenuated fisetin mediated cytoprotection in H9c2 cardiomyocytes subjected to ischemia reoxygenation by inducing mitotoxicity7
The effects of carvedilol, metoprolol and propranolol on cisplatin-induced kidney injury7
Lead and lead–arsenic combined exposure induces mortality and developmental impairments in zebrafish embryos: a study using wild-caught zebrafish from Bangladesh6
Decision tree algorithm can determine the outcome of repeated supratherapeutic ingestion (RSTI) exposure to acetaminophen: review of 4500 national poison data system cases6
Nebivolol alleviates liver damage caused by methotrexate via AKT1/Hif1α/eNOS signaling6
Protocatechuic acid protects against hepatorenal toxicities in rats exposed to Furan6
Anti-ischemic drug trimetazidine blocks mercury nephrotoxicity by suppressing renal redox imbalance, inflammatory stress and caspase-dependent apoptosis in rats6
Bromelain protects against cisplatin-induced ocular toxicity through mitigating oxidative stress and inflammation6
Investigation of the effects of three different generations of fluoroquinolone derivatives on antioxidant and immunotoxic enzyme levels in different rat tissues6
Investigation of protective effect of ellagic acid in phthalates-induced reproductive damage6
Betaine attenuates sodium arsenite-induced renal dysfunction in rats6
Carbamazepine-induced renal toxicity may be associated with oxidative stress and apoptosis in male rat6
The effect of melatonin on testis histological changes and spermatogenesis indexes in mice following treatment with dexamethasone6
Comparative cytotoxicity induced by parabens and their halogenated byproducts in human and fish cell lines6
Rutin ameliorates perfluorooctanoic acid-induced testicular injury in mice by reducing oxidative stress and improving lipid metabolism6
Ameliorating effect of rutin against diclofenac-induced cardiac injury in rats with underlying function of FABP3, MYL3, and ANP6
Mutagenic and teratogenic toxicity evaluation of Forsythia suspensa leaves aqueous extract6
The effects of minocycline in improving of methamphetamine withdrawal syndrome in male mice6
Effects of the copper oxide nanoparticles (CuO NPs) onGalleria mellonellahemocytes5
D-ribose-L-cysteine modulates lead acetate-induced hematobiochemical alterations, hormonal imbalance, and ovarian toxicity in adult female Wistar rats5
Long-term reproductive effects of benzo(a)pyrene at environmentally relevant dose on juvenile female rats5
The protective effect of chrysin against oxidative stress and organ toxicity in rats exposed to propetamphos5
Long-term toxicity of fluoroquinolones: a comprehensive review5
Subacute toxicity study of the ethanolic extract of Mesua ferrea (L.) flowers in rats5
Distribution, metabolism, excretion, and toxicity of implanted silver: a review5
Electronic cigarette aerosol increases the risk of organ dysfunction by enhancing oxidative stress and inflammation5
Eucalyptol alleviates cisplatin-induced kidney damage in rats5
Biochemical and histopathological analysis after sub-chronic administration of oxyresveratrol in Wistar rats5
Acute and sub-acute oral toxicity assessment of 5-hydroxy-1,4-naphthoquinone in mice5
Hesperidin via maintenance of mitochondrial function and antioxidant activity protects lithium toxicity in rat heart isolated mitochondria5
Toxicological assessment of electronic cigarette vaping: an emerging threat to force health, readiness and resilience in the U.S. Army5
The system of self-consistent models based on quasi-SMILES as a tool to predict the potential of nano-inhibitors of human lung carcinoma cell line A549 for different experimental conditions5
Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems5
Febuxostat, an inhibitor of xanthine oxidase, ameliorates ionizing radiation-induced lung injury by suppressing caspase-3, oxidative stress and NF-κB5
Effects of prolonged subchronic benzo(α)pyrene exposure on rat liver morphology and CYP1A expression during treatment with menadione, quercetin, or tocopherol5
Investigation into the protective effects of Hypericum Triquetrifolium Turra seed against cyclophosphamide-induced testicular injury in Sprague Dawley rats5
Genotoxic and mutagenic potential of 7-methylxanthine: an investigational drug molecule for the treatment of myopia5
Comparative evaluation of the effects of bisphenol derivatives on oxidative stress parameters in HepG2 cells5
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats5
Fluvastatin alleviates doxorubicin-induced cardiac and renal toxicity in rats via regulation of oxidative stress, inflammation, and apoptosis associated genes expressions5
Hepatoprotective effects of a chemically-characterized extract from artichoke (Cynara scolymus L.) against AFB1-induced toxicity in rats4
Analysis of suppressive effects of pesticide triazophos on leucocyte immune responses in a teleost,Channa Punctatus4
Further insights into the impact of rebamipide on gentamicin-induced nephrotoxicity in rats: modulation of SIRT1 and β-catenin/cyclin D1 pathways4
Effects of pinealectomy and crocin treatment on rats with isoproterenol-induced myocardial infarction4
Protective effects of lotus plumule ethanol extracts on bleomycin-induced pulmonary fibrosis in mice4
The effects of apelin-13 against cisplatin-induced nephrotoxicity in rats4
Impact of free curcumin and curcumin nanocapsules on viability and oxidative status of neural cell lines4
Ameliorative role of inducible nitric oxide synthase inhibitors against sodium arsenite-induced renal and hepatic dysfunction in rats4
The molecular interaction of human anti-apoptotic proteins and in silico ADMET, drug-likeness and toxicity computation of N-cyclohexylmethacrylamide4
MiADMSA abrogates sodium tungstate-induced oxidative stress in rats4
In vitro cytogenotoxic and mutagenic effects of Commiphora myrrha essential oil4
Interactive effect of carbendazim and imidacloprid on buffalo bone marrow derived mesenchymal stem cells: oxidative stress, cytotoxicity and genotoxicity4
A study on Wistar Albino rats: investigating protective role of ramelteon on liver damage caused by methotrexate4
Rupatadine protects the intestinal mucosa from injury by 5-flurouracil via modulation of inflammation, apoptosis and intestinal permeability4
Synthetic pyrethroids common metabolite 3-phenoxybenzoic acid induces caspase-3 and Bcl-2 mediated apoptosis in human hepatocyte cells4
The preventive effects of Centaurea maroccana Ball. extract against oxidative stress induced by cisplatin in mice brains: in vitro and in vivo studies4
A comparative study on the sensitivity of selected freshwater fishes against triclosan exposure4
Ethyl pyruvate attenuates cisplatin-induced ovarian injury in rats via activating Nrf2 pathway4
Curcumin mediates autophagy and apoptosis in granulosa cells: a study of integrated network pharmacology and molecular docking to elucidate toxicological mechanisms4
Sub-chronic toxicity of an aqueous extract of Epimedium sagittatum (Sieb. Et Zucc.) Maxim. in rats4
Lagerstroemia speciosa (L.) Pers., ethanolic leaves extract attenuates dapsone-induced liver inflammation in rats4
Non-permitted food colorants induced neurotoxicity in cerebellum of rat brain4
Phycocyanin improved alcohol-induced hepatorenal toxicity and behavior impairment in Wistar rats4
Investigation of the phytochemical composition and remedial effects of southern grape hyacinth (Muscari neglectum Guss. ex Ten.) plant extract against carbon tetrachloride-induced oxidative str4
In silico, in vitro, and in vivo investigation of antioxidant potential and toxicity of ethyl ferulate4
Mechanisms underlying citrinin-induced toxicity via oxidative stress and apoptosis-mediated by mitochondrial-dependent pathway in SH-SY5Y cells4
Influence of zinc oxide nanoparticles (ZnO NPs) on the hemocyte count and hemocyte-mediated immune responses of the Greater Wax Moth Galleria mellonella (Lepidoptera: Pyralidae)4
TiO 2 nanoparticles: green synthesis, characterization, and investigation of antimicrobial properties, and developmental toxicity in zebrafish ( Danio4
Exogenous glutathione protects against gentamicin-induced acute kidney injury by inhibiting NF-κB pathway, oxidative stress, and apoptosis and regulating PCNA4
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