Drug and Chemical Toxicology

Article	Citations
Pinealectomy and melatonin administration in rats: their effects on pulmonary edema induced by α-naphthylthiourea	54
Comparative study of the genotoxic activity of Artemisia vulgaris L. and Artemisia alba Turra extracts in vitro	20
Cytotoxic effect and induction of apoptosis in human cervical cancer cells by a wood extract from Prosopis laevigata	20
Opioid poisoning cases aged 50+ in the 2015–2020 National Poisoning Data System: suspected suicides versus unintentional poisoning and other intentional misuse/abuse	16
Assessment of cardiotoxicity induced by PFOS exposure and mechanism research via untarget metabolomics	16
Tinospora Cordifolia and Arabinogalactan in combination modulates benzo(a)pyrene-induced genotoxicity during lung carcinogenesis	15
Novel chlorinated oxime K870 protects rats against paraoxon poisoning better than obidoxime	14
Genotoxic and genoprotective effects of phytoestrogens: a systematic review	13
Toxicological evaluation of ethanolic extract of leaves from Doliocarpus dentatus in Swiss mice	13
Acute, repeated inhalation toxicity, respiratory system irritation, and mutagenicity studies of 1,1,2,2-tetrafluoroethane (HFC-134) as the impurity in the pharmaceutical propellant 1,1,1,2-tetrafluoro	13
Protective role of resveratrol and apigenin against toxic effects of bisphenol a in rat salivary gland	13
Cadmium and ketoprofen accumulation influences aquatic ecosystem demonstrated using in-vivo zebrafish model	12
Determination of histopathological effects and myoglobin, periostin gene-protein expression levels in Danio rerio muscle tissue after acaricide yoksorrun-5EC (hexythiazox) application	11
Hepatic histopathological and morphometric changes in male mice exposed to rosuvastatin from pre-puberty to adulthood: a possible adaptive hepatic response	11
Formulation and evaluation of solid lipid nanoparticles loaded with papaya seed chloroform extract for long-term antifertility effects on the male rat, Bandicota bengalensis	11
The protective effects of capsaicin on oxidative damage-induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats	11
Evaluating Water bitter leaf (Struchium sparganophora) and Scent Leaf (Ocimum gratissimum)extracts as sources of nutraceuticals against manganese-induced toxicity in fruit fly model	11
In silico and in vivo protective effect of Morus nigra leaves on oxidative damage induced by iron overload	10
The protective effect of N-acetyl cysteine against selenium toxicity and gamma irradiation in rats	10
Evaluation of genotoxic and mitotoxic effects of TAF-loaded chitosan nanoparticles in HepG2 cells	10
Omeprazole induces profibrotic gene expression in rat kidney: implication of TGF-β/Smad signaling pathway	10
Topiramate’s effects on normal and fatty liver	10
Amelioration of metabolic disorders in H9C2 cardiomyocytes induced by PM 2.5 treated with vitamin C	10
Acrylamide induces intrinsic apoptosis and inhibits protective autophagy via the ROS mediated mitochondrial dysfunction pathway in U87-MG cells	9
In vitro evaluation of the selective cytotoxicity and genotoxicity of three synthetic ortho -nitrobenzyl derivatives in human cancer cell lines, with	9

Gastroprotective mechanism of Talinum triangulare on ethanol-induced gastric ulcer in Wistar rats via inflammatory, antioxidant, and H	9
Perfluorooctane sulfonate (PFOS) triggers migration and invasion of esophageal squamous cell carcinoma cells via regulation of Zeb1	9
Effect of chlorpyrifos on some biochemical changes in Cyprinus carpio: the protective effect of ellagic acid	9
The PERK/ATF4/CHOP signaling branch of the unfolded protein response mediates cisplatin-induced ototoxicity in hair cells	9
Psoralen induces liver injuries through endoplasmic reticulum stress signaling in female mice	9
In vitro assessment of the antioxidative, toxicological and antimicrobial properties of battery of parabens	9
Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats	9
The role of ginger’s extract and N-acetylcysteine against docetaxel-induced oxidative stress and genetic disorder	8
Non-permitted food colorants induced neurotoxicity in cerebellum of rat brain	8
Resveratrol-mediated cardioprotection against myocardial ischemia-reperfusion injury was revoked by statin-induced mitochondrial alterations	8
Lipid-lowering, anti-inflammatory, and hepatoprotective effects of isorhamnetin on acetaminophen-induced hepatotoxicity in mice	8
Neurotoxic effects of carbamazepine on the mosquitofish Gambusia affinis	8
Silver nanoparticles’ impact on the gene expression of the cytosolic adaptor MyD-88 and the interferon regulatory factor IRF in the gills and digestive gland of mytilus galloprovinciali	8
The effects of minocycline in improving of methamphetamine withdrawal syndrome in male mice	8
Exposure to emamectin benzoate confers cytotoxic effects on human molt-4 T-cells and possible ameliorative role of vitamin E and dithiothreitol	8
Hepatoprotective effects of norgalanthamine on carbon tetrachloride induced-hepatotoxicity in mice	8
N ω -nitro-L-arginine, a nitric oxide synthase inhibitor, attenuates nickel-induced neurotoxicity	8
Anticonvulsant effectiveness of scopolamine against soman-induced seizures in African green monkeys	8
Investigation of genotoxic effects of rhododendron honey using three mammalian bioassays in vivo	7
Chlorogenic acid attenuates cisplatin-induced ovarian injury in rats	7
Long-term exposure to bisphenol-A causes oxidative stress-related alterations at the genetic and cellular levels in the mature ovary of adult zebrafish	7
Protective effects of resveratrol and avocado oil against paracetamol-induced hepatotoxicity in rats	7
Furan impairs cell function by inducing oxidative stress, DNA damage and apoptosis in mouse Sertoli cells in vitro	7
Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems	7
Apoptosis is involved in paraoxon-induced histological changes in rat cerebellum	7
Population pharmacokinetics and pharmacodynamics of L-asparaginase and its impact on the development of pancreatitis and hypersensitivity reactions in children with leukemia under treatment	6
Toxicity optimization of green zinc oxide quantum dots in zebrafish using Box-Behnken design: a novel approach for safer nanoparticle synthesis	6
Neuroprotective effects of fermented blueberry and black rice against particulate matter 2.5 μm-induced inflammation in vitro and in vivo	6
Alpha-mangostin attenuates the apoptotic pathway of abamectin in the fetal rats’ brain by targeting pro-oxidant stimulus, catecholaminergic neurotransmitters, and transcriptional regulation of reelin	6
Effects of electrospun fiber curcumin on bisphenol A exposed Caco-2 cells	6
Unraveling the hepatoprotective and anti-pancreatic cancer potential of Caralluma europaea : a comprehensive in vivo, in vitro and in sili	6
Is a non-cytotoxic and non-genotoxic novel bioinspired dipeptide structure synthesis possible for theragnostic applications?	6
Implications of atrazine concentrations in drinking water from Ijebu-North, Southwest Nigeria on the hypothalamic-pituitary-adrenal axis	6
Analysis of suppressive effects of pesticide triazophos on leucocyte immune responses in a teleost,Channa Punctatus	6
Aprepitant mitigates paclitaxel-induced neuropathic pain in rats via suppressing inflammatory pathways in dorsal root ganglia	6
Taurine and enzymatically modified isoquercitrin synergistically protect against the methotrexate-induced cardiotoxicity in rats: antioxidant and antiapoptotic effects	6
Changes in hormones, Leukocyte Telomere Length (LTL), and p16INK4a expression in SM-exposed individuals in favor of the cellular senescence	6
Evaluation of acute and subacute dermal toxicity of antibacterial bioactive glass-infused surgical cotton gauze in Wistar rats	6
Comparative toxicological evaluation of carvacrol, acetylcarvacrol anda fipronil-based pesticide in human blood cells	6
Effects of ellagic acid in the testes of streptozotocin induced diabetic rats	5
Liver function alterations among workers in the shoe industry due to combined low-level exposure to organic solvents	5
Interactive effect of carbendazim and imidacloprid on buffalo bone marrow derived mesenchymal stem cells: oxidative stress, cytotoxicity and genotoxicity	5
Eight-year epidemiological study for drug poisoning in Qassim, Saudi Arabia, 2008–2015	5
The ameliorative effect of rosmarinic acid and epigallocatechin gallate against doxorubicin-induced genotoxicity	5
Tissue-specific toxicity of clothianidin on rainbow trout (Oncorhynchus mykiss)	5
Bromelain protects against cisplatin-induced ocular toxicity through mitigating oxidative stress and inflammation	5
Evaluating the therapeutic effect and toxicity of theophylline in infertile men with asthenoteratozoospermia: a double-blind, randomized clinical trial study	5
Livogrit prevents Amiodarone-induced toxicity in experimental model of human liver (HepG2) cells and Caenorhabditis elegans by regulating redox homeostasis	5
Oxidative stress and inflammatory markers in streptozotocin-induced acute and subacute toxicity response	5
Quercetin prevents methylmercury-induced mitochondrial dysfunction in the cerebral cortex of mice	5

Rosuvastatin exposure in female Wistar rats alters uterine contractility and do not show evident (anti)estrogenic effects	5
Genotoxic effects of gadobutrol and gadoversetamide active substances used in magnetic resonance imaging in human peripheral lymphocytesin vitro	5
Correction	5
Investigation of the role of K ATP channels in the cytotoxic effect of cypermethrin on rat-derived aortic smooth muscle cells	5
Investigating the impact of external application of formalin and potassium permanganate on hematological, immunological, and biochemical profiles in Labeo rohita fingerl	5
A toxicological review of alkaloids	5
Atrazine residue in waters of Ijebu-North local government, Nigeria: implications on human health, hematological, and biochemical parameters	4
PM2.5from diesel exhaust attenuated fisetin mediated cytoprotection in H9c2 cardiomyocytes subjected to ischemia reoxygenation by inducing mitotoxicity	4
Should combined MTX and CoQ10 use be reconsidered in terms of steatosis? A biochemical, flow cytometry, histopathological experimental study	4
Phytochemical composition, cytotoxicity, antioxidant and antimicrobial responses of Lavandula dentata L. grown under different levels of heavy metals stress condition	4
Assessment of Toxicity and Wound Healing Activity of Selaginella Bryopteris Extract	4
In vitro cytogenetic analysis of two different anti-phosphates (sevelamer hydrochloride and calcium carbonate) agents used by patients with hyperphosphatemia	4
Evaluation of subchronic toxicity of the compound of diphenhydramine hydrochloride and caffeine after 28 days of repeated oral administration in Sprague-Dawley rats and beagle dogs	4
Linalool exhibits therapeutic and protective effects in a rat model of doxorubicin-induced kidney injury by modulating oxidative stress	4
Protective effect of neurotensin receptor-1 agonist PD 149163 against lipopolysaccharide-induced gut toxicity in mice	4
Outcome prediction of methadone poisoning in the United States: implications of machine learning in the National Poison Data System (NPDS)	4
MiADMSA abrogates sodium tungstate-induced oxidative stress in rats	4
Amelioration of modified chronic unpredictable stress usingCelastrus paniculatusseed oil alone and in combination with fluoxetine	4
Dichlorophene activates aryl hydrocarbon receptor (AhR) and indoleamine 2, 3-dioxygenase 1 (IDO1) to mediate splenotoxicity in rat	4
The inhibitory effects of pimozide, an antipsychotic drug, on voltage-gated K+ channels in rabbit coronary arterial smooth muscle cells	4
Co-administration of thymol and sulfoxaflor impedes the expression of reproductive toxicity in male rats	4
Chloroform extract of Calliandra portoricensis inhibits tumourigenic effect of N-methyl-N-nitrosourea and benzo(a)pyrene in breast experimental cancer	4
Manganese mitigates against hepatorenal oxidative stress, inflammation and caspase-3 activation in rats exposed to hexachlorobenzene	4
Exploring the toxicity profile of coriander ( C. sativum L.) essential oil: implications for translational toxicological research	4
Assessment of redox homeostasis via genotoxicity, cytotoxicity, apoptosis and NRF-2 in colorectal cancer cell lines after treatment with Ganoderma lucidum extract	4
Fluvastatin alleviates doxorubicin-induced cardiac and renal toxicity in rats via regulation of oxidative stress, inflammation, and apoptosis associated genes expressions	4
Anti-ischemic drug trimetazidine blocks mercury nephrotoxicity by suppressing renal redox imbalance, inflammatory stress and caspase-dependent apoptosis in rats	4
Toxicity of pesticide cocktails in amphibian larvae: understanding the impact of agricultural activity on aquatic ecosystems in the Salado River basin, Argentina	4
Sweet basil ( Ocimum basilicum ) leaf and seed extracts alleviate neuronal dysfunction in aluminum chloride-induced neurotoxicity in Drosophila melanogast	4
Hepatoprotective effects of a chemically-characterized extract from artichoke (Cynara scolymus L.) against AFB1-induced toxicity in rats	4
Ninety-day oral toxicological profiling of Kolaviron (an extract of Garcinia kola) in male and female rats	4
Sub-chronic toxicity of an aqueous extract of Epimedium sagittatum (Sieb. Et Zucc.) Maxim. in rats	4
Pelargonidin ameliorates reserpine-induced neuronal mitochondrial dysfunction and apoptotic cascade: a comparative in vivo study	4
Lagerstroemia speciosa (L.) Pers., ethanolic leaves extract attenuates dapsone-induced liver inflammation in rats	4
Two cases report of febuxostat-induced acute liver injury: acute heart failure as a probable risk factor?	4
Preparation, characterization, and toxicity evaluation of microemulsion formulation containing prunetin for potential oral applications	4
Ginsenoside Re attenuates 8-OH-DPAT-induced serotonergic behaviors in mice via interactive modulation between PKCδ gene and Nrf2	3
Effects of taxifolin on tramadol-induced oxidative and inflammatory liver injury in rats: an experimental study	3
Toxicological evaluation of LivLonga ® , a polyherbal combination, in rodents	3
Invisible enemies: evaluating human health threats of mosquito repellents through animal studies	3
Screening and toxicity evaluation of natural compounds as adenosine 2a and 2b receptor ligands: insights from molecular docking, dynamics, and ADMET analysis	3
In vitro cytogenotoxic and mutagenic effects of Commiphora myrrha essential oil	3
The comparison of the effect of Origanum vulgare L. extract and vitamin C on the gentamycin-induced nephrotoxicity in rats	3
Evaluation of acute and 28-day repeated dose toxicity of Tolypocladium sinense soft capsule in Sprague-Dawley rats	3
Assessment of imidacloprid induced genotoxicity in Pethia conchonius (Rosy barb), a common freshwater fish of India	3
Antibiotic sorption onto MPs in terrestrial environment: a critical review of the transport, bioaccumulation, ecotoxicological effects and prospects	3
Investigation of oxidative, inflammatory and apoptotic effects of favipiravir use alone and combined with vitamin C on brain tissue of elderly rats	3
Mitigating aluminum chloride-induced toxicity in Drosophila melanogaster with peptide fractions from Euphorbia species	3
Synergistic hepatoprotective effects of ω-3 and ω-6 fatty acids from Indian flax and sesame seed oils against CCl 4 -induced oxidative stress-mediated liver damage i	3
Acute and 13 weeks subchronic toxicological evaluation of the flavonoid-rich extract of Sophora flavescens	3
NO-mediated DNA damage induced by polystyrene nanoparticles triggers program cell death in mesenchymal stem cells	3
Vitamin E improves oxidative stress, apoptosis, and steroidogenesis impairment in glyphosate-induced mice	3
Linolenic acid stimulates eryptosis and hemolysis through oxidative stress and CK1α/MLKL: protective role of melatonin, urea, and polyethylene glycol	3
Ascorbic acid regulates in vitro and in vivo toxicogenetic effects of hydroxyurea on eukaryotic cells	3
Cytogenetic damage by vanadium(IV) and vanadium(III) on the bone marrow of mice	3
Determination of micronuclei frequency in Danio rerio for assessing genotoxicity induced by propineb	3
D-ribose-L-cysteine exhibits neuroprotective activity through inhibition of oxido-behavioral dysfunctions and modulated activities of neurotransmitters in the cerebellum of Juvenile mice exposed to et	3
Distribution, metabolism, excretion, and toxicity of implanted silver: a review	3
Evaluation of XQ528 tartrate on embryo-fetus developmental toxicity in SD rats and genotoxicity	3
Mutagenic and teratogenic toxicity evaluation of Forsythia suspensa leaves aqueous extract	3
Synthesized gold nanoparticles mediated by Crassocephalum rubens extract down-regulate KIM-1/NGAL genes and inhibit oxidative stress in cadmium-induced kidney damage in rats	3
Assessment of morin hydrate as a renal protective agent in rats subjected to methotrexate-induced nephrotoxicity	3
Protective efficacy of ramelteon on methotrexate-induced DNA damage	3
Correction	3
Toxicological analysis of synthetic dye orange red on expression of NFκB-mediated inflammatory markers in Wistar rats	3
Mitochondrial toxicity of selected natural compounds: in vitro assessment and in silico molecular docking and dynamics simulation	3
Assessing chromium toxicity across aquatic and terrestrial environments: a cross-species review	3
Carvacrol modulates antioxidant enzymes, DNA integrity, and apoptotic markers in zearalenone-exposed fetal rat liver	3
Comparative evaluation of natural and artificial sweeteners from DNA damage, oxidative stress, apoptosis, to development using Drosophila melanogaster	3
The incidence rate of allergic reactions induced by oxaliplatin is higher in patients with rectal cancer compared with colon cancer	3
DNA damage in workers exposed to mineral oils	3
Sulfoxaflor insecticide exhibits cytotoxic or genotoxic and apoptotic potential via oxidative stress-associated DNA damage in human blood lymphocytes cell cultures	3
Introduced paeoniflorin reduces the main toxicity induced by diosbulbin B, the major toxic compound of Dioscorea bulbifera L.: involved inhibiting inflammation and ferro	3
Study on the acute toxicity of sodium taurocholate via zebrafish mortality, behavioral response, and NMR-metabolomics analysis	3
Content of potentially toxic elements (PTEs) in coffee and coffee-based products: a meta-analysis study, Systematic review, and health risk assessment	3
Isolation and comparative genotoxicity screening of trichokonins VI and VIII on CHO-K1 cells	3
Asparagus falcatus L. (Asparagaceae) leaf extracts attenuate doxorubicin-induced renal toxicity via antioxidant, anti-inflammatory, and anti-apoptotic pathways	3
Naringenin mitigates cadmium-induced cell death, oxidative stress, mitochondrial dysfunction, and inflammation in KGN cells by regulating the expression of sirtuin-1	2
Beneficial effects of adipose-derived stromal vascular fraction on testicular injury caused by busulfan	2
Naringenin blocks hepatic cadmium accumulation and suppresses cadmium-induced hepatotoxicity via amelioration of oxidative inflammatory signaling and apoptosis in rats	2

Synthesis and evaluation of small organic molecule as reactivator of organophosphorus inhibited acetylcholinesterase	2
Isometamidium chloride alters redox status, down-regulates p53 and PARP1 genes while modulating at proteomic level in Droso	2
Protective effect of dexpanthenol against methotrexate-induced liver oxidative toxicity in rats	2
Protective effects of Biebersteinia multifida on sub-chronic toxicity of DZN in male Wistar rats: biochemical, hematological, and oxidative stress indices	2
Effects of low-dose ionizing radiation on the molecular pathways linking neurogenesis and autism spectrum disorders in zebrafish embryos	2
The protective effects of vitamins A, C, and E on zinc oxide nanoparticles (ZnO NPs)-induced liver oxidative stress in male Wistar rats	2
Tauroursodeoxycholic acid suppresses biliary epithelial cell apoptosis and endoplasmic reticulum stress by miR-107/NCK1 axis in a FXR-dependent manner	2
Genotoxicity evaluation of self-assembled-micelle inhibitory RNA-targeting amphiregulin (SAMiRNA-AREG), a novel siRNA nanoparticle for the treatment of fibrotic disease	2
Reproductive and developmental toxicity of α-terpineol in Wistar rats	2
Genotoxic, biochemical, cytotoxic and biomolecular alterations in the early-life stage of zebrafish exposed to diphenyl ether	2
Olea europaea L. leaf extract mitigates pulmonary inflammation and tissue destruction in Wistar rats induced by concurrent exposure to noise and tolue	2
Toxicity assessment of watermelon seed supplemented diet in rats	2
Antiandrogen enzalutamide induced genetic, cellular, and hepatic damages: amelioration by triterpene Lupeol	2
Specific and combined effects of dietary ethanol and arginine on Drosophila melanogaster	2
Neutralization of iron oxide magnetic nanoparticle aquatoxicity on Oncorhynchus mykiss via supplementation with ulexite	2
Exploring health beneficial effects of poisonous mushroom Paxillus involutus Batsch Fr.	2
Evaluation of oxidative stress and its association with drug therapy in inpatients treated for cocaine dependence	2
Exogenous glutathione protects against gentamicin-induced acute kidney injury by inhibiting NF-κB pathway, oxidative stress, and apoptosis and regulating PCNA	2
Pesticides analysis in alternative biological matrices	2
Saffron stigma extract and crocin play an important neuroprotective role in therapeutic measures against benzo[a]pyrene-induced behavioral alterations in zebrafish	2
The molecular interaction of human anti-apoptotic proteins and in silico ADMET, drug-likeness and toxicity computation of N-cyclohexylmethacrylamide	2
Protocatechuic acid protects against hepatorenal toxicities in rats exposed to Furan	2
Renal tubular response to titanium dioxide nanoparticles exposure	2
Repeated dose toxicity studies of Trichostatin A in Swiss albino mice through oral and intravenous route of administration with special emphasis on genotoxicity	2
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats	2
Probiotics modulation of the endotoxemic effect on the gut and liver of the lipopolysaccharide challenged mice	2
Toothpastes for children and their detergent contents affect molecular mechanisms of odontogenesis in zebrafish embryos	2
Evaluation of the non-clinical toxicity of an antiparasitic agent: diminazene aceturate	2
Single and repeat-dose toxicity and local tolerance assessment of newly developed oil emulsion adjuvant formulations for veterinary purposes	2
Assessment of genotoxicity and acute oral toxicity of a standardized Ocimum tenuiflorum extract (Holixer TM )	2
Potential neuroprotective effects of 2-hydroxypropyl-β cyclodextrin against amyloid β (1-42)-induced neurotoxicity on the rat hippocampus	2
TiO 2 nanoparticles: green synthesis, characterization, and investigation of antimicrobial properties, and developmental toxicity in zebrafish ( Danio	2
Modulatory effect of myricitrin against chromosome instability and cytostasis induced by bleomycin and oxaliplatin in CHO-K1 cells	2
Mutagenic and genotoxic in silico QSAR prediction of dimer impurity of gliflozins; canagliflozin, dapaglifozin, and emphagliflozin and in vitro	2
Preventive treatment with sodium para-aminosalicylic acid inhibits manganese-induced apoptosis and inflammation via the MAPK pathway in rat thalamus	2
Antioxidant and in vitro cytogenotoxic properties of Amburana cearensis (Allemão) A.C.Sm. leaf extract	2
Three-dimensional (3D) cell culture studies: a review of the field of toxicology	2
Toxicogenetic profile of the monoterpene alpha-terpineol on normal and tumor eukaryotic cells	2
The ameliorative effect of methanol extract of Ricinodendron heudelotii (Baill.) leaves on paracetamol-induced hepatotoxicity in Wistar rats	2
The system of self-consistent models based on quasi-SMILES as a tool to predict the potential of nano-inhibitors of human lung carcinoma cell line A549 for different experimental conditions	2
l -Theanine ameliorates motor deficit, mitochondrial dysfunction, and neurodegeneration against chronic tramadol induced rats model of Parkinson’s disease	2
Curcumin mediates autophagy and apoptosis in granulosa cells: a study of integrated network pharmacology and molecular docking to elucidate toxicological mechanisms	2
Ameliorative effects of nutritional minerals on lead-induced hematological alterations in male Wistar albino rats	2
Flavonoid-rich fraction of Lasianthera africana leaves alleviates hepatotoxicity induced by carbon tetrachloride in Wistar rats	2
Unraveling the neuroprotective mechanisms of naltrexone against aluminum-induced neurotoxicity	2
Methanol fraction ofFicus mucoso(welw) prevents iron-induced oxidative damage and alters mitochondrial dysfunction inDrosophila melanogaster	2
Fumaric acid protects rats from ciprofloxacin-provoked depression through modulating TLR4, Nrf-2, and p190-rho GTP	2
Acute and sub-acute toxicity study of ethanol extract from Nectandra leucantha Nees & Mart. (Lauraceae) barks	2
Effects of idebenone and coenzyme Q10 on NLRP3/caspase-1/IL-1β pathway regulation on ethanol-induced hepatotoxicity in rats	2
The effect of cut sizes and pH of tobacco leaf in smokeless tobacco products on the pharmacokinetics of nicotine	2
Lethal toxicity induced by combined ingestion of dietary acetic acid and carbamazepine	2
Alterations in gills and intestine of Danio rerio after exposure to acaricide yoksorrun-5EC (hexythiazox): histopathologic and morphometric evaluation	2
Enhanced antibacterial and genoprotective properties of nanoliposomal Satureja hortensis L. essential oil	2
Screening the immunotoxicity of different food preservative agents on the model organism Galleria mellonella L. (Lepidoptera: Pyralidae) larvae	2
Comparison of the cytotoxicity and zebrafish embryo toxicity of insect repellent ingredients: p-Menthane-3,8-diol synthesized by green chemistry from Eucalyptus citriodora	2
Protective effect of chrysin, a flavonoid, on the genotoxic activity of carboplatin in mice	1
Pentoxifylline inhibits phosgene-induced lung injury via improving hypoxia	1
Evaluation of immunotoxicity of iron oxide nanoparticles on coelomocytes of Eisenia fetida	1
Acute exposure to environmentally relevant concentrations of pharmaceutical pollutants induces neurobehavioral toxicity in zebrafish ( Danio rerio )	1
Verbascoside inhibits paraquate-induced pulmonary toxicity via modulating oxidative stress, inflammation, apoptosis and DNA damage in A549 cell	1
l-Thyroxine induces left ventricular remodeling and fibrosis in rats by upregulating miR-21 in a reactive oxygen-dependent mechanism: a protective role of N-acetylcysteine	1
Modulation of mitochondrial permeability transition pore opening by Myricetin and prediction of its-drug-like potential usingin silicoapproach	1
In silico molecular docking and in vitro analysis of atomoxetine	1
Long term integrated biomarker responses in freshwater African catfish Clarias gariepinus exposed to a new brand of herbicide fluazifop-p-butyl	1
Antioxidant, antinociceptive, anti-inflammatory, and hepatoprotective activities of pentacyclic triterpenes isolated from Ziziphus oxyphylla Edgew	1
Hydromorphone impurity 2,2-bishydromorphone does not exert mutagenic and clastogenic properties via in silico QSAR prediction and in vitro Ames and micronucleus test	1
Intestinal epithelial damage due to herbal compounds – an in vitro study	1
Rutin ameliorates perfluorooctanoic acid-induced testicular injury in mice by reducing oxidative stress and improving lipid metabolism	1
Chronic intraperitoneal injection of polyethylene glycol 200 in mice induces hippocampal neuroinflammation	1
Ameliorating effect of rutin against diclofenac-induced cardiac injury in rats with underlying function of FABP3, MYL3, and ANP	1
Protective effects of a polyherbal medicine, Majoon Suranjan against bisphenol-A induced genetic, oxidative and tissue damages	1
Study on the acute and subchronic oral toxicity of Calculus Bovis Sativus in rats	1
Analysis of key targets for 5-hydroxymethyl-2-furfural-induced lung cancer based on network toxicology, network informatics, and in vitro experiments	1
Nanomaterials in biology and medicine: a new perspective on its toxicity and applications	1
Artemisia vulgaris L., Artemisia alba Turra and their constituents reduce mitomycin C-induced genomic instability in human peripheral blood lymphocyte	1
Orally administered zingerone does not mitigate alcohol-induced hepatic oxidative stress in growing Sprague Dawley rat pups	1
Arrested Acetylene-Induced Pulmonary and Testicular Toxicity in Rats Through Treatment With Polyphenols	1
Estimating the impact of drug addiction causes heart damage	1
Nebivolol alleviates liver damage caused by methotrexate via AKT1/Hif1α/eNOS signaling	1
There and back again: a dendrimer’s tale	1
Evaluation of antifungal activity, mechanisms of action and toxicological profile of the synthetic amide 2-chloro- N -phenylacetamide	1
Single acute and repeated subacute toxicity evaluations of Annona atemoya leaf extract with in vitro anti-inflammatory potential	1
Ameliorative role of inducible nitric oxide synthase inhibitors against sodium arsenite-induced renal and hepatic dysfunction in rats	1
Neurotoxic and cardiotoxic effects of N-methyl-1-(naphthalen-2-yl)propan-2-amine (methamnetamine) and 1-phenyl-2-pyrrolidinylpentane (prolintane)	1
L-Carnitine alleviates hepatic and renal mitochondrial-dependent apoptotic progression induced by letrozole in female rats through modulation of Nrf-2, Cyt c and CASP-3 signaling	1
Comparative evaluation of the effects of bisphenol derivatives on oxidative stress parameters in HepG2 cells	1
Construction of an explanatory model for predicting hepatotoxicity: a case study of the potentially hepatotoxic components of Gardenia jasminoides	1
Effects of chlorpyrifos toxicity on brain, pseudobranchial neurosecretory system and swimming performance of a catfish, Heteropneustes fossilis	1
Hepatoprotective effect of Sophora moorcroftiana (Benth.) Benth.Ex baker seeds in vivo and in vitro	1
Influence of zinc oxide nanoparticles (ZnO NPs) on the hemocyte count and hemocyte-mediated immune responses of the Greater Wax Moth Galleria mellonella (Lepidoptera: Pyralidae)	1
Ethyl pyruvate attenuates cisplatin-induced ovarian injury in rats via activating Nrf2 pathway	1
Effect of lycopene on TiO 2 nanoforms induced oxidative stress and neuroinflammation in SH-SY5Y cells: an in vitro study	1
Identification and genotoxicity evaluation of potential impurities in rabeprazole sodium using in silico and in vitro analyses	1
Combined effect of fulvestrant and low dose BPA: comparative implications on EMT, apoptosis, and TGF-β1 signaling in HepG2 cells	1
Protective effects of curcumin against valproic acid induced brain kidney and liver damage in rats	1