Drug and Chemical Toxicology

Papers
(The median citation count of Drug and Chemical Toxicology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Evaluating Water bitter leaf (Struchium sparganophora) and Scent Leaf (Ocimum gratissimum)extracts as sources of nutraceuticals against manganese-induced toxicity in fruit fly model68
Evaluating the therapeutic effect and toxicity of theophylline in infertile men with asthenoteratozoospermia: a double-blind, randomized clinical trial study26
Toxicological evaluation of ethanolic extract of leaves from Doliocarpus dentatus in Swiss mice21
In vitro evaluation of the selective cytotoxicity and genotoxicity of three synthetic ortho -nitrobenzyl derivatives in human cancer cell lines, with 20
Tinospora Cordifolia and Arabinogalactan in combination modulates benzo(a)pyrene-induced genotoxicity during lung carcinogenesis19
Population pharmacokinetics and pharmacodynamics of L-asparaginase and its impact on the development of pancreatitis and hypersensitivity reactions in children with leukemia under treatment18
Pinealectomy and melatonin administration in rats: their effects on pulmonary edema induced by α-naphthylthiourea16
Non-permitted food colorants induced neurotoxicity in cerebellum of rat brain16
Opioid poisoning cases aged 50+ in the 2015–2020 National Poisoning Data System: suspected suicides versus unintentional poisoning and other intentional misuse/abuse16
Dichlorophene activates aryl hydrocarbon receptor (AhR) and indoleamine 2, 3-dioxygenase 1 (IDO1) to mediate splenotoxicity in rat15
Gastroprotective mechanism of Talinum triangulare on ethanol-induced gastric ulcer in Wistar rats via inflammatory, antioxidant, and H 15
Unraveling the hepatoprotective and anti-pancreatic cancer potential of Caralluma europaea : a comprehensive in vivo, in vitro and in sili15
Antioxidant capacity, acute and sub-acute oral toxicity, and in vivo anti-inflammatory effects of Tetradenia riparia hydroalcoholic extrac15
Oxidative stress and inflammatory markers in streptozotocin-induced acute and subacute toxicity response14
The ameliorative effect of rosmarinic acid and epigallocatechin gallate against doxorubicin-induced genotoxicity13
Investigation of the role of K ATP channels in the cytotoxic effect of cypermethrin on rat-derived aortic smooth muscle cells13
Changes in hormones, Leukocyte Telomere Length (LTL), and p16INK4a expression in SM-exposed individuals in favor of the cellular senescence13
Effect of chlorpyrifos on some biochemical changes in Cyprinus carpio: the protective effect of ellagic acid12
Amelioration of metabolic disorders in H9C2 cardiomyocytes induced by PM 2.5 treated with vitamin C12
Screening and toxicity evaluation of natural compounds as adenosine 2a and 2b receptor ligands: insights from molecular docking, dynamics, and ADMET analysis11
Co-administration of thymol and sulfoxaflor impedes the expression of reproductive toxicity in male rats11
Genotoxic effects of gadobutrol and gadoversetamide active substances used in magnetic resonance imaging in human peripheral lymphocytesin vitro11
Synergistic hepatoprotective effects of ω-3 and ω-6 fatty acids from Indian flax and sesame seed oils against CCl 4 -induced oxidative stress-mediated liver damage i11
Investigation of oxidative, inflammatory and apoptotic effects of favipiravir use alone and combined with vitamin C on brain tissue of elderly rats11
Pelargonidin ameliorates reserpine-induced neuronal mitochondrial dysfunction and apoptotic cascade: a comparative in vivo study11
Content of potentially toxic elements (PTEs) in coffee and coffee-based products: a meta-analysis study, Systematic review, and health risk assessment11
Manganese mitigates against hepatorenal oxidative stress, inflammation and caspase-3 activation in rats exposed to hexachlorobenzene11
Naringenin mitigates cadmium-induced cell death, oxidative stress, mitochondrial dysfunction, and inflammation in KGN cells by regulating the expression of sirtuin-110
Evaluation of acute and 28-day repeated dose toxicity of Tolypocladium sinense soft capsule in Sprague-Dawley rats10
NO-mediated DNA damage induced by polystyrene nanoparticles triggers program cell death in mesenchymal stem cells10
MiADMSA abrogates sodium tungstate-induced oxidative stress in rats10
Protective effect of neurotensin receptor-1 agonist PD 149163 against lipopolysaccharide-induced gut toxicity in mice10
Tauroursodeoxycholic acid suppresses biliary epithelial cell apoptosis and endoplasmic reticulum stress by miR-107/NCK1 axis in a FXR-dependent manner10
Assessment of morin hydrate as a renal protective agent in rats subjected to methotrexate-induced nephrotoxicity10
Saffron stigma extract and crocin play an important neuroprotective role in therapeutic measures against benzo[a]pyrene-induced behavioral alterations in zebrafish10
Toxicity of pesticide cocktails in amphibian larvae: understanding the impact of agricultural activity on aquatic ecosystems in the Salado River basin, Argentina10
Linolenic acid stimulates eryptosis and hemolysis through oxidative stress and CK1α/MLKL: protective role of melatonin, urea, and polyethylene glycol10
Toothpastes for children and their detergent contents affect molecular mechanisms of odontogenesis in zebrafish embryos9
Protective effect of dexpanthenol against methotrexate-induced liver oxidative toxicity in rats9
Fumaric acid protects rats from ciprofloxacin-provoked depression through modulating TLR4, Nrf-2, and p190-rho GTP9
TiO 2 nanoparticles: green synthesis, characterization, and investigation of antimicrobial properties, and developmental toxicity in zebrafish ( Danio9
Renal tubular response to titanium dioxide nanoparticles exposure9
Preventive treatment with sodium para-aminosalicylic acid inhibits manganese-induced apoptosis and inflammation via the MAPK pathway in rat thalamus9
Pentoxifylline inhibits phosgene-induced lung injury via improving hypoxia8
Single acute and repeated subacute toxicity evaluations of Annona atemoya leaf extract with in vitro anti-inflammatory potential8
Modulatory effect of myricitrin against chromosome instability and cytostasis induced by bleomycin and oxaliplatin in CHO-K1 cells8
Study on the acute and subchronic oral toxicity of Calculus Bovis Sativus in rats8
Long term integrated biomarker responses in freshwater African catfish Clarias gariepinus exposed to a new brand of herbicide fluazifop-p-butyl8
Antioxidant and in vitro cytogenotoxic properties of Amburana cearensis (Allemão) A.C.Sm. leaf extract8
Probiotics modulation of the endotoxemic effect on the gut and liver of the lipopolysaccharide challenged mice8
Ameliorative role of inducible nitric oxide synthase inhibitors against sodium arsenite-induced renal and hepatic dysfunction in rats8
Damage to the sarcoplasmic reticulum by venom of the Mexican black-tailed rattlesnake ( Crotalus molossus nigrescens ): inhibition of the Ca 2+ 7
Ethyl pyruvate attenuates cisplatin-induced ovarian injury in rats via activating Nrf2 pathway7
B-Raf inhibitor vemurafenib counteracts sulfur mustard-induced epidermal impairment through MAPK/ERK signaling7
Effect of adenosine triphosphate on methylphenidate-induced oxidative and inflammatory kidney damage in rats7
Assessment of the effect of sodium tetraborate on oxidative stress, inflammation, and apoptosis in lead-induced nephrotoxicity7
Cyclosporine-A induced cytotoxicity within HepG2 cells by inhibiting PXR mediated CYP3A4/CYP3A5/MRP2 pathway7
Effect ofMoringa oleiferaleaf extract on valproate-induced oxidative damage in muscle6
Fluoroquinolone antibiotics in the aquatic environment: environmental distribution, the research status and eco-toxicity6
The protective effect of chrysin against oxidative stress and organ toxicity in rats exposed to propetamphos6
Chronic bisphenol A exposure induces temporal neurobehavioral transformation and augmented chromatin condensation in the periventricular gray zone of zebrafish brain6
Toxicological assays in the evaluation of safety assessment of fibrinolytic enzymes6
Nigella sativa oil reduces oxidative/nitrosative stress in the salivary gland of rats exposed to total cranial irradiation6
Computational modeling ( in silico ) methods combined with ecotoxicological experiments ( in vivo ) to predict the environmental risks of 6
Involvement of oxidative stress and toll-like receptor-4 signaling pathways in gentamicin-induced nephrotoxicity in male Sprague Dawley rats6
In vitro antibacterial and anti-inflammatory effects of Anacardium occidentale L. extracts and their toxicity on PBMCs and zebrafish embryos6
Safety assessment of Wuzhuyu decoction extract: acute and subacute oral toxicity studies in rats6
Pre-clinical and cellular safety assessment of oral administered DHA rich microalgae oil from Schizochytrium sp. (Strain ATCC-20889): acute, sub-chronic and genotoxicity6
Chronic levamisole exposure in male rats alters sexual behavior and induces apoptosis in the testis6
Uncoupling as initiating event in mitochondrial dysfunction after diuron exposure6
Long-term reproductive effects of benzo(a)pyrene at environmentally relevant dose on juvenile female rats6
Prognostic value of systemic immune-inflammation index and monocyte-to-HDL-cholesterol ratio in early cardio-cerebral complications in elderly patients with acute severe carbon monoxide poisoning6
Assessment of the toxicity of different antiretroviral drugs and their combinations on Sertoli and Leydig cells6
Metformin ameliorates cardiopulmonary toxicity induced by chlorpyrifos6
Phycocyanin improved alcohol-induced hepatorenal toxicity and behavior impairment in Wistar rats5
A comparison of the potential of melatonin and tryptophan to ameliorate CCl 4 -induced hepatic and renal toxicity in Wistar rats5
Ameliorative effect of gallic acid on cisplatin-induced ovarian toxicity in rats5
Genotoxic and genoprotective effects of phytoestrogens: a systematic review5
A comparison of cell death mechanisms of antioxidants, butylated hydroxyanisole and butylated hydroxytoluene5
Electronic cigarette aerosol increases the risk of organ dysfunction by enhancing oxidative stress and inflammation5
Both acute glyphosate and the aminomethylphosphonic acid intoxication decreased the acetylcholinesterase activity in rat hippocampus, prefrontal cortex and gastrocnemius muscle5
Comparative cytotoxicity induced by parabens and their halogenated byproducts in human and fish cell lines5
Salvianolic acid A suppresses CCl4-induced liver fibrosis through regulating the Nrf2/HO-1, NF-κB/IκBα, p38 MAPK, and JAK1/STAT3 signaling pathways5
Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems5
A study on Wistar Albino rats: investigating protective role of ramelteon on liver damage caused by methotrexate5
Protective effects ofp-coumaric acid against gentamicin-induced nephrotoxicity in rats5
Therapeutic effects of thymoquinone or capsaicin on acrylamide-induced reproductive toxicity in rats mediated by their effect on oxidative stress, inflammation, and tight junction integrity5
Omeprazole induces profibrotic gene expression in rat kidney: implication of TGF-β/Smad signaling pathway5
Eight-year epidemiological study for drug poisoning in Qassim, Saudi Arabia, 2008–20155
In vitro cytogenotoxic evaluation of aripiprazole on human peripheral lymphocytes and computational molecular docking analysis4
Dermatoprotective effect of Moringa oleifera leaf extract on sodium valproate-induced skin damage in rats4
Potential neuroprotective effects of 2-hydroxypropyl-β cyclodextrin against amyloid β (1-42)-induced neurotoxicity on the rat hippocampus4
A dual-acting aldose reductase inhibitor impedes oxidative and carbonyl stress in tissues of fructose- and streptozotocin-induced rats: comparison with antioxidant stobadine4
Toxicogenetic profile of the monoterpene alpha-terpineol on normal and tumor eukaryotic cells4
Exploring the toxicity profile of coriander ( C. sativum L.) essential oil: implications for translational toxicological research4
Exploring health beneficial effects of poisonous mushroom Paxillus involutus Batsch Fr.4
Preclinical safety profile of RC88-ADC:a novel mesothelin-targeted antibody conjugated with Monomethyl auristatin E4
New oxomethacrylate and acetamide: synthesis, characterization, and their computational approaches: molecular docking, molecular dynamics, and ADME analyses4
Long-term toxicity of fluoroquinolones: a comprehensive review4
Effects of acetaminophen exposure on behavior and erythrocyte nuclear morphology of juvenile Oreochromis niloticus4
Induced oxidative stress and apoptosis by 1-bromopropane in SH-SY5Y cells correlates with inhibition of Nrf2 function4
Combined effect of fulvestrant and low dose BPA: comparative implications on EMT, apoptosis, and TGF-β1 signaling in HepG2 cells4
Single and repeat-dose toxicity and local tolerance assessment of newly developed oil emulsion adjuvant formulations for veterinary purposes4
Reproductive and developmental toxicity of α-terpineol in Wistar rats4
Acute and 13 weeks subchronic toxicological evaluation of the flavonoid-rich extract of Sophora flavescens4
Phytochemical composition, cytotoxicity, antioxidant and antimicrobial responses of Lavandula dentata L. grown under different levels of heavy metals stress condition4
Hydromorphone impurity 2,2-bishydromorphone does not exert mutagenic and clastogenic properties via in silico QSAR prediction and in vitro Ames and micronucleus test4
In vitro study of the toxic and teratogenic effects of prednisolone, azathioprine and mycophenolate mofetile on embryological development of rats4
Evaluation of antifungal activity, mechanisms of action and toxicological profile of the synthetic amide 2-chloro- N -phenylacetamide4
Betaine attenuates sodium arsenite-induced renal dysfunction in rats4
Protective effects of perindopril against indomethacin-induced gastric mucosal damage through modulation of DDAH-1/ADMA and ACE-2/ANG-(1-7) signaling pathways4
Cardiotoxicity induced by xanthatin via activating apoptosis and ERS pathways in zebrafish4
Sildenafil aggravates adriamycin-induced testicular toxicity in rats; a preliminary investigation4
Ameliorative effects of nutritional minerals on lead-induced hematological alterations in male Wistar albino rats4
MiR-27b-3p ameliorates DOX-induced cardiotoxicity by suppressing myocardial inflammation and oxidative stress in mice and cardiomyocytes4
Evaluation of XQ528 tartrate on embryo-fetus developmental toxicity in SD rats and genotoxicity4
Artemisia vulgaris L., Artemisia alba Turra and their constituents reduce mitomycin C-induced genomic instability in human peripheral blood lymphocyte4
In vitro and in vivo genotoxicity assessments of Ficus erecta Thunb. leaves extract support its functional and pharmace4
In vitro screening of genotoxicity and mutagenicity of pyriproxyfen in human lymphocytes and Salmonella typhimurium TA98 and TA100 strains4
Acute exposure to environmentally relevant concentrations of pharmaceutical pollutants induces neurobehavioral toxicity in zebrafish ( Danio rerio )4
Effects of burnt tire-ash on Na+/K+, Ca2+-ATPase, serum immunoglobulin and brain acetylcholinesterase activities in clarias gariepinus (Burchell, 1822)4
Furan impairs cell function by inducing oxidative stress, DNA damage and apoptosis in mouse Sertoli cells in vitro3
Further insights into the impact of rebamipide on gentamicin-induced nephrotoxicity in rats: modulation of SIRT1 and β-catenin/cyclin D1 pathways3
Investigation of the phytochemical composition and remedial effects of southern grape hyacinth (Muscari neglectum Guss. ex Ten.) plant extract against carbon tetrachloride-induced oxidative str3
Formulation and evaluation of solid lipid nanoparticles loaded with papaya seed chloroform extract for long-term antifertility effects on the male rat, Bandicota bengalensis3
Hepatoprotective effect of methanol fruit extract of Punica granatum L in highly active antiretroviral therapy-induced toxicity in Wistar rats3
Ferroptosis: action and mechanism of chemical/drug-induced liver injury3
Acute toxicity and biodistribution assessment of quantum dots conjugated to lectins from Schinus terebinthifolia leaves (SteLL) and Punica granatum 3
The effect of preconditioning agents on cardiotoxicity and neurotoxicity of carbon monoxide poisoning in animal studies: a systematic review3
Treatment with human umbilical cord blood serum in a gentamicin-induced nephrotoxicity model in rats3
Cadmium and ketoprofen accumulation influences aquatic ecosystem demonstrated using in-vivo zebrafish model3
Effects of electrospun fiber curcumin on bisphenol A exposed Caco-2 cells3
Investigating the impact of external application of formalin and potassium permanganate on hematological, immunological, and biochemical profiles in Labeo rohita fingerl3
Perfluorooctane sulfonate (PFOS) triggers migration and invasion of esophageal squamous cell carcinoma cells via regulation of Zeb13
Attenuation of methotrexate induced hepatotoxicity by epigallocatechin 3-gallate3
Glabridin attenuates paracetamol-induced liver injury in mice via CYP2E1-mediated inhibition of oxidative stress3
Mechanistic study of copper oxide, zinc oxide, cadmium oxide, and silver nanoparticles-mediated toxicity on the probiotic Lactobacillus reuteri3
Effects of quetiapine administration on sperm quality and testicular histology3
Di (2-ethyl hexyl) phthalate and its metabolite-induced metabolic syndrome: a review of molecular mechanisms3
Toxicological evaluation of oral exposure to isoniazid: behavioral, biochemical, and histopathological assessments in rats3
Protective effects of a chemically characterized extract fromsolanum torvumleaves on acetaminophen-induced liver injury3
Effects of pinealectomy and crocin treatment on rats with isoproterenol-induced myocardial infarction3
Correction3
The role of ginger’s extract and N-acetylcysteine against docetaxel-induced oxidative stress and genetic disorder3
Protective effects of royal jelly and Echinacea against moxifloxacin-induced renal and hepatic injury in rats3
Assessment of cardiotoxicity induced by PFOS exposure and mechanism research via untarget metabolomics3
Study of cardioprotective activity of the methanolic extract of the aerial parts of Bauhinia madagascariensis compared to Bauhinia purpurea 3
Liquid mosquito repellent induces toxic effects in zebrafish3
Effects of caffeic acid phenethyl ester use and inhibition of p42/44 MAP kinase signal pathway on caveolin 1 gene expression and antioxidant system in chronic renal failure model of rats3
Correction3
Phytochemical analysis, in silico study and toxicity profile ofCycas pectinataBuch.-Ham seed in mice3
Mandarin peel ethanolic extract attenuates diclofenac sodium induced hepatorenal toxicity in rats by mitigating oxidative stress and inflammation3
Potential protective effects of Acacia nilotica (L.) against gentamicin - induced nephrotoxicity by suppressing renal redox imbalance, inflammatory stress and caspase-de3
Chlorogenic acid attenuates cisplatin-induced ovarian injury in rats3
The effects of minocycline in improving of methamphetamine withdrawal syndrome in male mice3
Quercetin prevents methylmercury-induced mitochondrial dysfunction in the cerebral cortex of mice3
In vitro assessment of the antioxidative, toxicological and antimicrobial properties of battery of parabens3
Arrested Acetylene-Induced Pulmonary and Testicular Toxicity in Rats Through Treatment With Polyphenols2
Mitochondrial injury induced by triclopyr in the rat liver2
Pre-clinical acute oral toxicity and subacute neurotoxicity risk assessments on sprague dawley rats treated with single dose or repeated doses of flavonoid-enriched fraction extracted from 2
Mancozeb induces cytogenotoxicity in meristematic cells of Allium cepa L2
Humic acid attenuates cisplatin-induced nephrotoxicity in rats2
Morphine attenuates neurotoxic effects of MPTP in zebrafish embryos by regulating oxidant/antioxidant balance and acetylcholinesterase activity2
Human red blood cell acetylcholinesterase activity: a revisit after fifteen years2
Synthesis and evaluation of small organic molecule as reactivator of organophosphorus inhibited acetylcholinesterase2
Transcription of biological aging markers (ANRIL, P16 INK4a , TBX2, and TERRA) and their correlations with severity of sulfur mustard exposure in veterans2
The system of self-consistent models based on quasi-SMILES as a tool to predict the potential of nano-inhibitors of human lung carcinoma cell line A549 for different experimental conditions2
In vitro cytogenotoxic and mutagenic effects of Commiphora myrrha essential oil2
Acute and sub-acute oral toxicity assessment of 5-hydroxy-1,4-naphthoquinone in mice2
The incidence rate of allergic reactions induced by oxaliplatin is higher in patients with rectal cancer compared with colon cancer2
Effects of sodium hydrosulfide (NaHS) on cisplatin-induced hepatic and cardiac toxicity2
The inhibitory effects of pimozide, an antipsychotic drug, on voltage-gated K+ channels in rabbit coronary arterial smooth muscle cells2
Synergistic toxicity of glyphosate- and 2,4-Dichlorophenoxyacetic acid-based formulations on Caenorhabditis elegans2
L-Carnitine alleviates hepatic and renal mitochondrial-dependent apoptotic progression induced by letrozole in female rats through modulation of Nrf-2, Cyt c and CASP-3 signaling2
Pre-imaginal exposure to mancozeb induces morphological and behavioral deficits and oxidative damage in Drosophila melanogaster2
Interconnected environmental challenges: heavy metal–drug interactions and their impacts on ecosystems2
Hypolipidemic potential and safety profile of the ethanolic extract and flour of the peel of Passiflora Cincinnata Mast. (Passifloraceae) in mice2
Carbamazepine-induced renal toxicity may be associated with oxidative stress and apoptosis in male rat2
Effects of chlorpyrifos toxicity on brain, pseudobranchial neurosecretory system and swimming performance of a catfish, Heteropneustes fossilis2
Linalool reverses benzene-induced cytotoxicity, oxidative stress and lysosomal/mitochondrial damages in human lymphocytes2
The ameliorative effect of methanol extract of Ricinodendron heudelotii (Baill.) leaves on paracetamol-induced hepatotoxicity in Wistar rats2
Ginkgo biloba leaf extract alleviates paraquat-induced RLE-6TN cell damage via the miR-155-5p/SIRT1/TLR4 axis2
Evaluation of immunological adjuvant activities of saponin rich fraction from the fruits of Asparagus adscendens Roxb. with less adverse reactions2
Effects of carvacrol on ketamine-induced cardiac injury in rats: an experimental study2
Eucalyptol alleviates cisplatin-induced kidney damage in rats2
In vitro cytogenetic analysis of two different anti-phosphates (sevelamer hydrochloride and calcium carbonate) agents used by patients with hyperphosphatemia2
Hepatoprotective effects of a chemically-characterized extract from artichoke (Cynara scolymus L.) against AFB1-induced toxicity in rats2
Impact of free curcumin and curcumin nanocapsules on viability and oxidative status of neural cell lines2
Study on the acute toxicity of sodium taurocholate via zebrafish mortality, behavioral response, and NMR-metabolomics analysis2
Neuroprotective potential of solanesol against tramadol induced zebrafish model of Parkinson’s disease: insights from neurobehavioral, molecular, and neurochemical evidence2
Introduced paeoniflorin reduces the main toxicity induced by diosbulbin B, the major toxic compound of Dioscorea bulbifera L.: involved inhibiting inflammation and ferro2
The neuroprotective effect of 1,25-dyhydroxyvitamin D 3 (calcitriol) and probiotics on the rotenone-induced neurotoxicity model in SH-SY5Y cells2
Evaluation of oxidative stress and its association with drug therapy in inpatients treated for cocaine dependence2
Effect of lycopene on TiO 2 nanoforms induced oxidative stress and neuroinflammation in SH-SY5Y cells: an in vitro study2
Orally administered zingerone does not mitigate alcohol-induced hepatic oxidative stress in growing Sprague Dawley rat pups2
Comparative analysis of the detrimental in vitro effects of three fusariotoxins on the selected structural and functional characteristics of rabbit spermatozoa2
Beneficial effects of adipose-derived stromal vascular fraction on testicular injury caused by busulfan2
Toxicity of ciprofloxacin and ofloxacin to Moina macrocopa and investigation of p -value adjustments for (eco)toxicological studies2
Exogenous glutathione protects against gentamicin-induced acute kidney injury by inhibiting NF-κB pathway, oxidative stress, and apoptosis and regulating PCNA2
Preclinical toxicological assessment of polydatin in zebrafish model2
Application of bioinformatics techniques to discovery of mechanisms by which plasticizers promote acute myelogenous leukemia2
Decision tree algorithm can determine the outcome of repeated supratherapeutic ingestion (RSTI) exposure to acetaminophen: review of 4500 national poison data system cases2
The administration of methyl and butyl parabens interferes with the enzymatic antioxidant system and induces genotoxicity in rat testis: possible relation to male infertility2
Lethal toxicity induced by combined ingestion of dietary acetic acid and carbamazepine2
Metabolic syndrome prevalence in Mexican individuals exposed to polycyclic aromatic hydrocarbons and their association with an increased risk of cardiovascular events2
Neuroprotective effects of gastrodin against bisphenol A induced-ADHD-like symptoms in rats2
Combination of metformin and sub-therapeutic dose of valproic acid prevent valproic acid-induced toxicity in animal model of epilepsy2
Toxicological analysis of synthetic dye orange red on expression of NFκB-mediated inflammatory markers in Wistar rats2
Hepatoprotective effect of Sophora moorcroftiana (Benth.) Benth.Ex baker seeds in vivo and in vitro2
Is a non-cytotoxic and non-genotoxic novel bioinspired dipeptide structure synthesis possible for theragnostic applications?2
Unusual dimeric flavonoids (brachydins) induce ultrastructural membrane alterations associated with antitumor activity in cancer cell lines2
Silver nanoparticles’ impact on the gene expression of the cytosolic adaptor MyD-88 and the interferon regulatory factor IRF in the gills and digestive gland of mytilus galloprovinciali1
In vivo and in silico anti-inflammatory activity of Artemisia vulgaris and β-caryophyllene oxide in carrageenan-induced1
Protective effects of a polyherbal medicine, Majoon Suranjan against bisphenol-A induced genetic, oxidative and tissue damages1
Verbascoside inhibits paraquate-induced pulmonary toxicity via modulating oxidative stress, inflammation, apoptosis and DNA damage in A549 cell1
Metabonomic and transcriptomic analyses of Tripterygium glycosides tablet-induced hepatotoxicity in rats1
Temporal analysis of paracetamol-induced hepatotoxicity1
Evaluation of the toxicological effects of favipiravir (T-705) on liver and kidney in rats: biochemical and histopathological approach1
Ginsenoside Rk1 exerts protective effects of LPS-induced podocyte apoptosis and inflammation by inactivating JAK2/STAT3 and NF-κB pathways1
Mechanistic insight into the hepatoprotective effect of Moringa oleifera Lam leaf extract and telmisartan against carbon tetrachloride-induced liver fibrosis: plausible 1
Phenelzine protects against acetaminophen induced apoptosis in HepG2 cells1
Comparative evaluation of the effects of bisphenol derivatives on oxidative stress parameters in HepG2 cells1
Borassus flabellifer Linn haustorium methanol extract mitigates fluoride-induced apoptosis by enhancing Nrf2/Haeme oxygenase 1 –dependent glutathione metabolism in intestinal epithe1
Intestinal epithelial damage due to herbal compounds – an in vitro study1
Evaluation of immunotoxicity of iron oxide nanoparticles on coelomocytes of Eisenia fetida1
Enhanced antibacterial and genoprotective properties of nanoliposomal Satureja hortensis L. essential oil1
Artesunate does not affect oocyte maturation and early embryo development of bovine1
Effect of chronic alcohol consumption on myocardial apoptosis in the rat model of isoproterenol-induced myocardial injury and investigation on the cardioprotective role of calpain inhibitor 11
Acute organophosphate and carbamate pesticide poisonings – a five-year survey from the National Poison Control Center Of Serbia1
Chemical characterization of tobacco-free “modern” oral nicotine pouches and their position on the toxicant and risk continuums1
PBAT-modified starch blended film extract induces in vitro toxicity in L-02 cells: induction of oxidative stress, inflammation, and modulation of AMPK pathway1
Aflatoxin B 1 and fumonisin B 1 exposure and adverse birth outcomes in HIV-infected and HIV-uninfected women from Harare, Zimbabwe1
Interactions of alumina and polystyrene nanoparticles with the innate immune system of Galleria mellonella1
Acute and subacute oral toxicity evaluation of Ayurvedic formulation Tapyadi loha in rats1
Neurotoxic and cardiotoxic effects of N-methyl-1-(naphthalen-2-yl)propan-2-amine (methamnetamine) and 1-phenyl-2-pyrrolidinylpentane (prolintane)1
Identification, trace level quantification, and in silico assessment of potential genotoxic impurity in Famotidine1
Novel synthesized, characterization and in vitro toxicological evaluation of amino acid-based-cerium oxide nanoparticles (CeO 2 NPs)1
Vinpocetine attenuates methotrexate-induced hippocampal intoxication via Keap-1/Nrf2, NF-κB/AP-1, and apoptotic pathways in rats1
Protective effects of curcumin against valproic acid induced brain kidney and liver damage in rats1
N ω -nitro-L-arginine, a nitric oxide synthase inhibitor, attenuates nickel-induced neurotoxicity1
Untargeted metabolic profiling of high-dose methotrexate toxicity shows alteration in betaine metabolism1
Genotoxic potential of different nano-silver halides in cultured human lymphocyte cells1
Protective effect of dapagliflozin against cyclosporine A-induced nephrotoxicity1
Molecular docking, ADME properties and synthesis of thiophene sulfonamide derivatives1
The sub-acute toxicity of kavalactone in rats: a study of the effect of oral doses and the mechanism of toxicity in combination with ethanol1
Borax attenuates oxidative stress, inflammation, and apoptosis by modulating Nrf2/ROS balance in acrylamide-induced neurotoxicity in rainbow trout1
Biochemical and histopathological analysis after sub-chronic administration of oxyresveratrol in Wistar rats1
Toxicity of commercial and pure forms of three nonsteroidal anti-inflammatory drugs in Xenopus laevis embryos before and after ozonation1
Construction of an explanatory model for predicting hepatotoxicity: a case study of the potentially hepatotoxic components of Gardenia jasminoides1
Some relevant mitigating agents of chronic aflatoxin exposure: a treatise1
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