Drug and Chemical Toxicology

Papers
(The median citation count of Drug and Chemical Toxicology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Investigation of the role of K ATP channels in the cytotoxic effect of cypermethrin on rat-derived aortic smooth muscle cells29
Population pharmacokinetics and pharmacodynamics of L-asparaginase and its impact on the development of pancreatitis and hypersensitivity reactions in children with leukemia under treatment24
Unraveling the hepatoprotective and anti-pancreatic cancer potential of Caralluma europaea : a comprehensive in vivo, in vitro and in sili22
Oxidative stress and inflammatory markers in streptozotocin-induced acute and subacute toxicity response20
The ameliorative effect of rosmarinic acid and epigallocatechin gallate against doxorubicin-induced genotoxicity19
Boldine activates Nrf2/ARE signaling to alleviate 5-fluorouracil-induced apoptosis, oxidative stress and inflammation in liver tissue of rats19
Amelioration of metabolic disorders in H9C2 cardiomyocytes induced by PM 2.5 treated with vitamin C17
Synthesis and multidimensional investigation of a tetra-substituted imidazole derivative: Spectroscopy, DFT/NLO properties, toxicity analysis, molecular docking, and dynamics simulation17
Changes in hormones, Leukocyte Telomere Length (LTL), and p16INK4a expression in SM-exposed individuals in favor of the cellular senescence17
Lipid profile, toxicity, and antioxidant potential of flavonoid-rich babassu mesocarp extract after simulated human digestion17
The effect on paraoxonase and arylesterase activities of bee pollen against deltamethrin in Cyprinus carpio16
Antioxidant capacity, acute and sub-acute oral toxicity, and in vivo anti-inflammatory effects of Tetradenia riparia 15
Gastroprotective mechanism of Talinum triangulare on ethanol-induced gastric ulcer in Wistar rats via inflammatory, antioxidant, and H 15
Co-administration of thymol and sulfoxaflor impedes the expression of reproductive toxicity in male rats14
Pinealectomy and melatonin administration in rats: their effects on pulmonary edema induced by α-naphthylthiourea14
In vitro evaluation of the selective cytotoxicity and genotoxicity of three synthetic ortho -nitrobenzyl derivatives in human cancer cell lines, with 14
Impact of placental polycyclic aromatic hydrocarbons accumulation on neonatal birth outcomes14
Investigation of oxidative, inflammatory and apoptotic effects of favipiravir use alone and combined with vitamin C on brain tissue of elderly rats13
Toxicity of pesticide cocktails in amphibian larvae: understanding the impact of agricultural activity on aquatic ecosystems in the Salado River basin, Argentina13
Tauroursodeoxycholic acid suppresses biliary epithelial cell apoptosis and endoplasmic reticulum stress by miR-107/NCK1 axis in a FXR-dependent manner13
Evaluation of acute and 28-day repeated dose toxicity of Tolypocladium sinense soft capsule in Sprague-Dawley rats13
Phenytoin as an emerging pollutant on non-target aquatic invertebrates: effects on Lamellidens marginalis12
Evaluation of therapeutic effects of royal jelly versus Nigella sativa oil on some brain areas affected by acute methanol poisoning in rats12
Acute and sub-acute toxicological evaluation of a bioactive compound mixture in healthy Wistar rats12
Screening and toxicity evaluation of natural compounds as adenosine 2a and 2b receptor ligands: insights from molecular docking, dynamics, and ADMET analysis11
Assessment of morin hydrate as a renal protective agent in rats subjected to methotrexate-induced nephrotoxicity11
N-nitrosodimethylamine increased glucose production by promoting hyperglycemia in hepatocyte via AMPK signaling pathway in vivo and in vitro11
Linolenic acid stimulates eryptosis and hemolysis through oxidative stress and CK1α/MLKL: protective role of melatonin, urea, and polyethylene glycol11
NO-mediated DNA damage induced by polystyrene nanoparticles triggers program cell death in mesenchymal stem cells11
Content of potentially toxic elements (PTEs) in coffee and coffee-based products: a meta-analysis study, Systematic review, and health risk assessment10
Probiotics modulation of the endotoxemic effect on the gut and liver of the lipopolysaccharide challenged mice10
Silymarin attenuates cobalt chloride-induced redox imbalance and cardio-renal dysfunctions in rats10
Aspirin’s therapeutic mechanism against diesel particulate matter-induced lung injury revealed by network pharmacology and experimental models10
Toothpastes for children and their detergent contents affect molecular mechanisms of odontogenesis in zebrafish embryos9
Saffron stigma extract and crocin play an important neuroprotective role in therapeutic measures against benzo[a]pyrene-induced behavioral alterations in zebrafish9
Toxicity study of compound honeysuckle moisturizing Chinese herbal extract by oral gavage for 13 weeks in sprague dawley rats9
Modulatory effect of myricitrin against chromosome instability and cytostasis induced by bleomycin and oxaliplatin in CHO-K1 cells9
Naringenin mitigates cadmium-induced cell death, oxidative stress, mitochondrial dysfunction, and inflammation in KGN cells by regulating the expression of sirtuin-19
Fumaric acid protects rats from ciprofloxacin-provoked depression through modulating TLR4, Nrf-2, and p190-rho GTP9
TiO 2 nanoparticles: green synthesis, characterization, and investigation of antimicrobial properties, and developmental toxicity in zebrafish ( Danio9
Damage to the sarcoplasmic reticulum by venom of the Mexican black-tailed rattlesnake ( Crotalus molossus nigrescens ): inhibition of the Ca 2+ 8
Renal tubular response to titanium dioxide nanoparticles exposure8
Toxicity of elemental selenium and selenium substances after pulmonary exposure; and environmental and occupational air concentrations: a review8
Protective effect of dexpanthenol against methotrexate-induced liver oxidative toxicity in rats8
Study on the acute and subchronic oral toxicity of Calculus Bovis Sativus in rats8
Long term integrated biomarker responses in freshwater African catfish Clarias gariepinus exposed to a new brand of herbicide fluazifop-p-butyl8
Pentoxifylline inhibits phosgene-induced lung injury via improving hypoxia8
Ethyl pyruvate attenuates cisplatin-induced ovarian injury in rats via activating Nrf2 pathway8
Single acute and repeated subacute toxicity evaluations of Annona atemoya leaf extract with in vitro anti-inflammatory potential8
Cyclosporine-A induced cytotoxicity within HepG2 cells by inhibiting PXR mediated CYP3A4/CYP3A5/MRP2 pathway7
Dose-dependent nephrotoxicity of hexaconazole following subchronic exposure in Swiss albino mice7
Safety assessment of Wuzhuyu decoction extract: acute and subacute oral toxicity studies in rats7
Evaluation of toxicological profile of omeprazole degradation impurities in an intravenous drug product: omeprazole-sulfone and omeprazole-N-oxide7
Kidney damage following a 90-day subchronic inhalation exposure to HTP aerosol in SD rats7
Metabolomics reveals formonetin mitigates neurotoxicity of CL-20 on neuron cells7
Prognostic value of systemic immune-inflammation index and monocyte-to-HDL-cholesterol ratio in early cardio-cerebral complications in elderly patients with acute severe carbon monoxide poisoning7
Assessment of the effect of sodium tetraborate on oxidative stress, inflammation, and apoptosis in lead-induced nephrotoxicity7
Carvacrol alleviates hepatorenal apoptosis in rats following exposure to lambda-cyhalothrin by targeting the Trx1/Prx1/Bcl2 pathway: in vivo and molecula7
Effect of adenosine triphosphate on methylphenidate-induced oxidative and inflammatory kidney damage in rats7
Pharmacological synergistic multi-target of Curcuma longa compounds to minimise the ototoxic effects and resistance of cisplatin in ovarian cancer treatm7
Toxicological assays in the evaluation of safety assessment of fibrinolytic enzymes7
Long-term reproductive effects of benzo(a)pyrene at environmentally relevant dose on juvenile female rats7
Assessment of the toxicity of different antiretroviral drugs and their combinations on Sertoli and Leydig cells7
Phycocyanin improved alcohol-induced hepatorenal toxicity and behavior impairment in Wistar rats6
Uncoupling as initiating event in mitochondrial dysfunction after diuron exposure6
Pre-clinical and cellular safety assessment of oral administered DHA rich microalgae oil from Schizochytrium sp. (Strain ATCC-20889): acute, sub-chronic and genotoxicity6
A comparison of the potential of melatonin and tryptophan to ameliorate CCl 4 -induced hepatic and renal toxicity in Wistar rats6
Both acute glyphosate and the aminomethylphosphonic acid intoxication decreased the acetylcholinesterase activity in rat hippocampus, prefrontal cortex and gastrocnemius muscle6
Genotoxic and genoprotective effects of phytoestrogens: a systematic review6
Omeprazole induces profibrotic gene expression in rat kidney: implication of TGF-β/Smad signaling pathway6
Comparative cytotoxicity induced by parabens and their halogenated byproducts in human and fish cell lines6
Role of endoplasmic reticulum stress in di(2-ethylhexyl) phthalate–induced renal toxicity and its amelioration by 4-phenylbutyric acid6
Silymarin ameliorates post-weaning bisphenol A exposure-induced cardiotoxicity via suppression of TLR4/VCAM signaling in male Wistar rats6
Chronic levamisole exposure in male rats alters sexual behavior and induces apoptosis in the testis6
Physcion alleviates cisplatin-induced apo in HK-2 cells by activating the apo signaling for treating acute kidney injury: Integrating network pharmacology and informatics6
Eight-year epidemiological study for drug poisoning in Qassim, Saudi Arabia, 2008–20156
Computational modeling ( in silico ) methods combined with ecotoxicological experiments ( in vivo ) to predict the environmental risks of 6
Effect ofMoringa oleiferaleaf extract on valproate-induced oxidative damage in muscle6
Metformin ameliorates cardiopulmonary toxicity induced by chlorpyrifos6
Nigella sativa oil reduces oxidative/nitrosative stress in the salivary gland of rats exposed to total cranial irradiation6
Acute and subacute toxicity of ethanol leaf extract of Urtica simensis Hochst. ex A. Rich in rats6
Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems6
Effects of methiopropamine on cognitive function and monoaminergic systems in mice6
Fluoroquinolone antibiotics in the aquatic environment: environmental distribution, the research status and eco-toxicity6
Toxicogenetic profile of the monoterpene alpha-terpineol on normal and tumor eukaryotic cells5
Exploring health beneficial effects of poisonous mushroom Paxillus involutus Batsch Fr.5
Co-administered chitosan and ivy leaf extract reduce deltamethrin-induced testicular toxicity5
In vivo and in silico toxicity profiling of a novel 1,5-benzodiazepine derivative5
Exploring the toxicity profile of coriander ( C. sativum L.) essential oil: implications for translational toxicological research5
Computational design and evaluation of low-toxicity saquinavir analogues targeting the catalytic dyad and oxyanion-hole loop of SARS-CoV-2 Mpro: insights from ensemble docking, molecular dynamics, dyn5
In vitro and in vivo genotoxicity assessments of Ficus erecta Thunb. leaves ext5
A dual-acting aldose reductase inhibitor impedes oxidative and carbonyl stress in tissues of fructose- and streptozotocin-induced rats: comparison with antioxidant stobadine5
Glyphosate in the Iberian Peninsula: Evaluating risks to Iberian wildlife5
Evaluation of plasticizer toxicity effects and mechanisms in gastric cancer based on network toxicology and molecular docking5
Evaluation of XQ528 tartrate on embryo-fetus developmental toxicity in SD rats and genotoxicity5
Protective potential of crocin against cadmium-induced oxidative pancreatitis and liver injury in female rats5
Phytochemical composition, cytotoxicity, antioxidant and antimicrobial responses of Lavandula dentata L. grown under different levels of heavy metals stress condition5
Reproductive and developmental toxicity of α-terpineol in Wistar rats5
Single and repeat-dose toxicity and local tolerance assessment of newly developed oil emulsion adjuvant formulations for veterinary purposes5
Potential neuroprotective effects of 2-hydroxypropyl-β cyclodextrin against amyloid β (1-42)-induced neurotoxicity on the rat hippocampus5
Exploring the toxicity mechanisms of acetyl tributyl citrate in premature ovarian insufficiency via network toxicology and molecular docking5
Interest of biochemical monitoring of liver function for patients under anti-tuberculosis treatment5
MiR-27b-3p ameliorates DOX-induced cardiotoxicity by suppressing myocardial inflammation and oxidative stress in mice and cardiomyocytes5
Induced oxidative stress and apoptosis by 1-bromopropane in SH-SY5Y cells correlates with inhibition of Nrf2 function4
Acute exposure to environmentally relevant concentrations of pharmaceutical pollutants induces neurobehavioral toxicity in zebrafish ( Danio rerio )4
Acute toxicity and biodistribution assessment of quantum dots conjugated to lectins from Schinus terebinthifolia leaves (SteLL) and Punica granatum 4
Ferroptosis: action and mechanism of chemical/drug-induced liver injury4
In-silico toxicity assessment of polychlorinated naphthalenes in water ecosystem by Monte Carlo-based QSAR studies4
Attenuation of methotrexate induced hepatotoxicity by epigallocatechin 3-gallate4
Heavy metal mixture induced hippocampal toxicity involve biometal accumulation, increase in oxidative stress, inflammation, and caspase-3 activation in rats via Nrf-2/HO-1/BDNF pathway4
Assessment of differences in urinary heavy metal concentrations and environmental factors between children with autism spectrum disorder and neurotypical controls4
Effects of acetaminophen exposure on behavior and erythrocyte nuclear morphology of juvenile Oreochromis niloticus4
Integrating network toxicology and molecular dynamics simulations to unveil the pathogenic mechanism of benzyl butyl phthalate in atopic dermatitis4
Impact of benzophenone-2 exposure on the reproductive outcomes in adult female mice4
Xenobiotic modalities impacting the thyroid 3H framework of hormonogenesis, homeostasis, and human health4
Pharmacological and toxicological effects of paracetamol: current knowledge and a review4
Synergistic hepatoprotection by supplementing Saussurea costus (falc.) lipsch and Glycyrrhiza glabra L. in combination against Diethylnitr4
Acute and subacute dermal toxicity analysis of film forming topical spray of meloxicam: in vitro and in vivo 4
Potential protective effects of Acacia nilotica (L.) against gentamicin - induced nephrotoxicity by suppressing renal redox imbalance, inflammatory stress and caspase-de4
Hepatoprotective effect of methanol fruit extract of Punica granatum L in highly active antiretroviral therapy-induced toxicity in Wistar rats4
Di (2-ethyl hexyl) phthalate and its metabolite-induced metabolic syndrome: a review of molecular mechanisms4
In vitro screening of genotoxicity and mutagenicity of pyriproxyfen in human lymphocytes and Salmonella typhimurium TA98 and TA100 strains4
Cardiotoxicity induced by xanthatin via activating apoptosis and ERS pathways in zebrafish4
New oxomethacrylate and acetamide: synthesis, characterization, and their computational approaches: molecular docking, molecular dynamics, and ADME analyses4
In vitro cytogenotoxic evaluation of aripiprazole on human peripheral lymphocytes and computational molecular docking analysis4
Dermatoprotective effect of Moringa oleifera leaf extract on sodium valproate-induced skin damage in rats4
Synthesis, in vivo, in silico toxicological evaluation, and safety assessment of novel methyl 4-amino-1,9b-dihydrochromeno[3,4-c] pyrrole-1-carboxylate4
Mandarin peel ethanolic extract attenuates diclofenac sodium induced hepatorenal toxicity in rats by mitigating oxidative stress and inflammation4
Protective effects of royal jelly and Echinacea against moxifloxacin-induced renal and hepatic injury in rats4
Mechanistic study of copper oxide, zinc oxide, cadmium oxide, and silver nanoparticles-mediated toxicity on the probiotic Lactobacillus reuteri4
Further insights into the impact of rebamipide on gentamicin-induced nephrotoxicity in rats: modulation of SIRT1 and β-catenin/cyclin D1 pathways4
Possible genotoxic effects of dapagliflozin using SMART and comet tests, and behavioral toxicity in Drosophila melanogaster4
Correction4
Long-term toxicity of fluoroquinolones: a comprehensive review4
Oxidative stress and toxicity induced by copper and zinc oxide nanoparticles in liver and kidney tissues of male mice4
Evaluation of antifungal activity, mechanisms of action and toxicological profile of the synthetic amide 2-chloro- N -phenylacetamide4
Artemisia vulgaris L., Artemisia alba Turra and their constituents reduce mitomycin C-induced genomic instability in human peripheral blood lymphocyte4
Hepatoprotective effects of a chemically-characterized extract from artichoke (Cynara scolymus L.) against AFB1-induced toxicity in rats3
Study on the acute toxicity of sodium taurocholate via zebrafish mortality, behavioral response, and NMR-metabolomics analysis3
Evaluation of oxidative stress and its association with drug therapy in inpatients treated for cocaine dependence3
Amelioration of cyclophosphamide-induced myelosuppression by the methanol fraction of Talinum fruticosum3
Biological effects of epoxy resins on the human body: toxicity and allergic reactions3
DNA damage induced by fungicides triadimefon, triadimenol, and their mixture in human lymphocytes: cytogenotoxicity and computational analysis of metabolic pathways3
Hepatoprotective effects of cirsimaritin against CCl 4 -induced oxidative stress, inflammation, and apoptosis in rats3
Lethal toxicity induced by combined ingestion of dietary acetic acid and carbamazepine3
Introduced paeoniflorin reduces the main toxicity induced by diosbulbin B, the major toxic compound of Dioscorea bulbifera L.: involved inhibiting inflammation and ferro3
In vitro cytogenetic analysis of two different anti-phosphates (sevelamer hydrochloride and calcium carbonate) agents used by patients with hyperphosphatemia3
Chlorogenic acid attenuates cisplatin-induced ovarian injury in rats3
Is a non-cytotoxic and non-genotoxic novel bioinspired dipeptide structure synthesis possible for theragnostic applications?3
Evaluation of Hepatotoxic effects of azo dye Acid Red 119 in freshwater fish Channa punctata3
Investigating the impact of external application of formalin and potassium permanganate on hematological, immunological, and biochemical profiles in Labeo rohita fingerl3
Synergistic toxicity of glyphosate- and 2,4-Dichlorophenoxyacetic acid-based formulations on Caenorhabditis elegans3
Application of bioinformatics techniques to discovery of mechanisms by which plasticizers promote acute myelogenous leukemia3
Beneficial effects of adipose-derived stromal vascular fraction on testicular injury caused by busulfan3
Synthesis and evaluation of small organic molecule as reactivator of organophosphorus inhibited acetylcholinesterase3
The administration of methyl and butyl parabens interferes with the enzymatic antioxidant system and induces genotoxicity in rat testis: possible relation to male infertility3
Formulation and evaluation of solid lipid nanoparticles loaded with papaya seed chloroform extract for long-term antifertility effects on the male rat, Bandicota bengalensis3
Neuroprotective effects of gastrodin against bisphenol A induced-ADHD-like symptoms in rats3
Quinestrol nanoparticle-based formulation for long-term oral contraception against the wild female rats, Bandicota bengalensis3
In vitro assessment of the antioxidative, toxicological and antimicrobial properties of battery of parabens3
Correction3
Furan impairs cell function by inducing oxidative stress, DNA damage and apoptosis in mouse Sertoli cells in vitro3
Quercetin prevents methylmercury-induced mitochondrial dysfunction in the cerebral cortex of mice3
The incidence rate of allergic reactions induced by oxaliplatin is higher in patients with rectal cancer compared with colon cancer3
Phenolic profile, in vitro antioxidant and safety evaluation of extract obtained from Citrus maxima Burm. 3
Humic acid attenuates cisplatin-induced nephrotoxicity in rats3
The system of self-consistent models based on quasi-SMILES as a tool to predict the potential of nano-inhibitors of human lung carcinoma cell line A549 for different experimental conditions3
Pre-clinical acute oral toxicity and subacute neurotoxicity risk assessments on sprague dawley rats treated with single dose or repeated doses of flavonoid-enriched fraction extracted from 3
The ameliorative effect of methanol extract of Ricinodendron heudelotii (Baill.) leaves on paracetamol-induced hepatotoxicity in Wistar rats3
Oridonin reduces cisplatin-induced cardiac damage: targeting oxidative stress and inflammation in chemotherapy3
The role of lncRNA H19/Hmox1 axis regulating ferroptosis in anthracycline-induced cardiotoxicity3
Assessment of cardiotoxicity induced by PFOS exposure and mechanism research via untarget metabolomics3
Cadmium and ketoprofen accumulation influences aquatic ecosystem demonstrated using in-vivo zebrafish model3
Liquid mosquito repellent induces toxic effects in zebrafish3
Human red blood cell acetylcholinesterase activity: a revisit after fifteen years2
Metabolic syndrome prevalence in Mexican individuals exposed to polycyclic aromatic hydrocarbons and their association with an increased risk of cardiovascular events2
Effects of sodium hydrosulfide (NaHS) on cisplatin-induced hepatic and cardiac toxicity2
Deferoxamine halt rotenone-induced Parkinson’s like symptoms in experimental rats: biochemical, neuroinflammatory, neurotransmitters, and histological evidence2
A new perspective on the neurotoxic mechanisms of six typical per- and polyfluoroalkyl substances (PFAS): insights from integrating network toxicology and random forest algorithm2
Evaluation of Cymbopogon citratus (lemongrass) leaf extract: phytochemical screening, antimicrobial activities, cytotoxicity, antioxidant properties, and2
Effects of carvacrol on ketamine-induced cardiac injury in rats: an experimental study2
Eucalyptol alleviates cisplatin-induced kidney damage in rats2
Subchronic oral administration of Tamoxifen in hormonally intact female rats induces dose-dependent maladaptive behavioral phenotypes2
Multibiomarker assessment of the ecotoxic effects of naproxen in African fresh water catfish ( Clarias gariepinus ) juveniles2
A single oral exposure to polyethylene terephthalate microplastics causes mild metabolic and gastrointestinal disruption: dose and sex determinants2
Effects of low-dose ionizing radiation on the molecular pathways linking neurogenesis and autism spectrum disorders in zebrafish embryos2
Curcumin and quercetin can ameliorate arsenic and smokeless tobacco induced reproductive toxicity in female mice2
Livogrit prevents Amiodarone-induced toxicity in experimental model of human liver (HepG2) cells and Caenorhabditis elegans by regulating redox homeostasis2
Preclinical toxicological assessment of polydatin in zebrafish model2
Taurine and enzymatically modified isoquercitrin synergistically protect against the methotrexate-induced cardiotoxicity in rats: antioxidant and antiapoptotic effects2
Pubertal atrazine exposure promotes adipocyte hypertrophy and hepatic steatosis in adult mice on a high-fat diet2
Toxicity optimization of green zinc oxide quantum dots in zebrafish using Box-Behnken design: a novel approach for safer nanoparticle synthesis2
Myricetin mitigates trifloxystrobin neurotoxicity by modulating the integrated stress response pathway and antioxidant defense in sH-SY5Y cells2
Rumex hastatus leaves extract alleviates Triclosan-induced reproductive toxicity and improves fertility by modulating oxidative stress2
Combination of metformin and sub-therapeutic dose of valproic acid prevent valproic acid-induced toxicity in animal model of epilepsy2
Mitochondrial injury induced by triclopyr in the rat liver2
Effects of chlorpyrifos toxicity on brain, pseudobranchial neurosecretory system and swimming performance of a catfish, Heteropneustes fossilis2
Interconnected environmental challenges: heavy metal–drug interactions and their impacts on ecosystems2
Toxicity of ciprofloxacin and ofloxacin to Moina macrocopa and investigation of p -value adjustments for (eco)toxicological studies2
Evaluation of genotoxic and mitotoxic effects of TAF-loaded chitosan nanoparticles in HepG2 cells2
Acute and sub-acute oral toxicity assessment of 5-hydroxy-1,4-naphthoquinone in mice2
Correction2
MicroRNA (miR)-489-3p contributes to lipopolysaccharide-induced HK-2 cell injury by targeting RIPK4 and inactivating the β-catenin signaling2
Evaluation of subchronic toxicity of the compound of diphenhydramine hydrochloride and caffeine after 28 days of repeated oral administration in Sprague-Dawley rats and beagle dogs2
Identification of the chemical constituents of Juglans regia ethanol extract by L-MS/MS and its effects on 5-FU-induced autophagy, oxidative stress, and 2
Aprepitant mitigates paclitaxel-induced neuropathic pain in rats via suppressing inflammatory pathways in dorsal root ganglia2
Decision tree algorithm can determine the outcome of repeated supratherapeutic ingestion (RSTI) exposure to acetaminophen: review of 4500 national poison data system cases2
Network toxicology and machine learning reveal key molecular targets and pathways of mono-2-ethylhexyl phthalate-induced atherosclerosis2
Oral acute and subacute toxicity studies as well as safety pharmacology in beagle dogs of total lignans from Arctii Fructus2
Hepatic histopathological and morphometric changes in male mice exposed to rosuvastatin from pre-puberty to adulthood: a possible adaptive hepatic response2
Neuroprotective potential of solanesol against tramadol induced zebrafish model of Parkinson’s disease: insights from neurobehavioral, molecular, and neurochemical evidence2
Histological and flow cytometric evaluation of astaxanthin’s effects against cyclophosphamide induced heart injury in rats2
Orally administered zingerone does not mitigate alcohol-induced hepatic oxidative stress in growing Sprague Dawley rat pups2
Mancozeb induces cytogenotoxicity in meristematic cells of Allium cepa L2
Effect of lycopene on TiO 2 nanoforms induced oxidative stress and neuroinflammation in SH-SY5Y cells: an in vitro study2
Topiramate exacerbates liver damage: a study on NAFLD, nitrosative stress and apoptosis2
The neuroprotective effect of 1,25-dyhydroxyvitamin D 3 (calcitriol) and probiotics on the rotenone-induced neurotoxicity model in SH-SY5Y cells2
In vivo hepatic effects and post-exposure recovery following polyethylene terephthalate microplastic ingestion in Swiss Albino mice ( Mus musculus2
Comparative evaluation of natural and artificial sweeteners from DNA damage, oxidative stress, apoptosis, to development using Drosophila melanogaster2
Assessing chromium toxicity across aquatic and terrestrial environments: a cross-species review2
Transcription of biological aging markers (ANRIL, P16 INK4a , TBX2, and TERRA) and their correlations with severity of sulfur mustard exposure in veterans2
Topiramate’s effects on normal and fatty liver2
Ginkgo biloba leaf extract alleviates paraquat-induced RLE-6TN cell damage via the miR-155-5p/SIRT1/TLR4 axis2
Novel synthesized, characterization and in vitro toxicological evaluation of amino acid-based-cerium oxide nanoparticles (CeO 2 NPs)2
Synergistic effect of piperine on curcumin in cisplatin-induced nephrotoxicity through DNA fragmentation and cytokines gene expressions2
Determination of micronuclei frequency in Danio rerio for assessing genotoxicity induced by propineb2
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