Drug and Chemical Toxicology

Article	Citations
Chemical characterization of tobacco-free “modern” oral nicotine pouches and their position on the toxicant and risk continuums	45
Formaldehyde toxicity reports from in vitro and in vivo studies: a review and updated data	35
Nutritional supplementation of gallic acid ameliorates Alzheimer-type hippocampal neurodegeneration and cognitive impairment induced by aluminum chloride exposure in adult Wistar rats	28
Nephroprotective effect of ferulic acid on gentamicin-induced nephrotoxicity in female rats	22
Zingerone protects liver and kidney tissues by preventing oxidative stress, inflammation, and apoptosis in methotrexate-treated rats	21
Rifampicin decreases neuroinflammation to maintain mitochondrial function and calcium homeostasis in rotenone-treated zebrafish	20
Evaluation of genotoxicity induced by herbicide pendimethalin in fresh water fish Clarias batrachus (linn.) and possible role of oxidative stress in induced DNA damage	19
The protective effect of Morin against ifosfamide-induced acute liver injury in rats associated with the inhibition of DNA damage and apoptosis	18
Characterization and neuroprotective properties of alkaloid extract of Vernonia amygdalina Delile in experimental models of Alzheimer’s disease	18
In-vivo and in-silico toxicity studies of daidzein: an isoflavone from soy	17
Toxicological impact of sodium benzoate on inflammatory cytokines, oxidative stress and biochemical markers in male Wistar rats	16
Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats	16
Escin attenuates oxidative damage, apoptosis and lipid peroxidation in a model of cyclophosphamide-induced liver damage	16
Protection of CCl4-induced hepatic and renal damage by linalool	15
Ameliorative effect of gallic acid on cisplatin-induced ovarian toxicity in rats	15
Linalool exhibits therapeutic and protective effects in a rat model of doxorubicin-induced kidney injury by modulating oxidative stress	15
Selenium and L-carnitine protects from valproic acid-Induced oxidative stress and mitochondrial damages in rat cortical neurons	15
Hepatoprotective effect of Ginkgo biloba extract against methotrexate-induced hepatotoxicity via targeting STAT3/miRNA-21 axis	14
Hepatoprotective effect of Raspberry ketone and white tea against acrylamide-induced toxicity in rats	14
The comparison of the effect of Origanum vulgare L. extract and vitamin C on the gentamycin-induced nephrotoxicity in rats	14
Miconazole and terbinafine induced reactive oxygen species accumulation and topical toxicity in human keratinocytes	13
Benzo(a)pyrene affects proliferation with reference to metabolic genes and ROS/HIF-1α/HO-1 signaling in A549 and MCF-7 cancer cells	13
The outbreak of methanol intoxication during COVID-19 pandemic: prevalence of brain lesions and its predisposing factors	13
Melatonin modulates copper-induced anxiety-like, depression-like and memory impairments by acting on hippocampal oxidative stress in rat	13
Shaddock (Citrus maxima) peels extract restores cognitive function, cholinergic and purinergic enzyme systems in scopolamine-induced amnesic rats	12

Brazil nut prevents oxidative DNA damage in type 2 diabetes patients	12
The protective effect of fluted pumpkin seeds against atrazine-induced testicular injury	12
Ellagic acid alleviates clozapine‑induced oxidative stress and mitochondrial dysfunction in cardiomyocytes	12
Linalool reverses benzene-induced cytotoxicity, oxidative stress and lysosomal/mitochondrial damages in human lymphocytes	12
Acute toxic effects of chlorpyrifos on pseudobranchial neurosecretory system, brain regions and locomotory behavior of an air-breathing catfish, Heteropneustes fossilis (Bloch 1794)	12
Placental levels of polycyclic aromatic hydrocarbons (PAHs) and their association with birth weight of infants	12
Borassus flabellifer haustorium extract prevents pro-oxidant mediated cell death and LPS-induced inflammation	12
Evaluation of the acute toxic effect of azoxystrobin on non-target crayfish (Astacus leptodactylus Eschscholtz, 1823) by using oxidative stress enzymes, ATPases and cholinesterase as biomarkers	12
Glabridin attenuates paracetamol-induced liver injury in mice via CYP2E1-mediated inhibition of oxidative stress	11
Morphine attenuates neurotoxic effects of MPTP in zebrafish embryos by regulating oxidant/antioxidant balance and acetylcholinesterase activity	11
A comparison of cell death mechanisms of antioxidants, butylated hydroxyanisole and butylated hydroxytoluene	11
Acrylamide induces intrinsic apoptosis and inhibits protective autophagy via the ROS mediated mitochondrial dysfunction pathway in U87-MG cells	11
The protective effects of vitamins A, C, and E on zinc oxide nanoparticles (ZnO NPs)-induced liver oxidative stress in male Wistar rats	11
L-Carnitine alleviates hepatic and renal mitochondrial-dependent apoptotic progression induced by letrozole in female rats through modulation of Nrf-2, Cyt c and CASP-3 signaling	10
Effect of carnosic acid on acrylamide induced neurotoxicity: in vivo and in vitro experiments	10
Risk assessment of elevated blood lead concentrations in the adult population using a decision tree approach	10
Mechanism of phthalate esters in the progression and development of breast cancer	10
The effect of sulfamethoxazole on oxidative stress indices in zebrafish (Danio rerio)	10
Acute and subchronic toxicity studies of rhein in immature and d-galactose-induced aged mice and its potential hepatotoxicity mechanisms	10
Neurotoxicity of poly(propylene imine) glycodendrimers	10
Role of aluminum exposure on Alzheimer’s disease and related glycogen synthase kinase pathway	10
Effects of ellagic acid in the testes of streptozotocin induced diabetic rats	10
Alogliptin attenuates cyclophosphamide-induced nephrotoxicity: a novel therapeutic approach through modulating MAP3K/JNK/SMAD3 signaling cascade	9
The impact of filtered water-pipe smoke on healthy versus cancer cells and their neurodegenerative role on AMPA receptor	9
The genotoxic effects of mixture of aluminum, arsenic, cadmium, cobalt, and chromium on the gill tissue of adult zebrafish (Danio rerio, Hamilton 1822)	9
Health risk assessment of 42 pesticide residues in Tieguanyin tea from Fujian, China	9
Antiandrogen enzalutamide induced genetic, cellular, and hepatic damages: amelioration by triterpene Lupeol	9
Salvianolic acid A suppresses CCl4-induced liver fibrosis through regulating the Nrf2/HO-1, NF-κB/IκBα, p38 MAPK, and JAK1/STAT3 signaling pathways	9
Effects of burnt tire-ash on Na+/K+, Ca2+-ATPase, serum immunoglobulin and brain acetylcholinesterase activities in clarias gariepinus (Burchell, 1822)	9
The role of ginger’s extract and N-acetylcysteine against docetaxel-induced oxidative stress and genetic disorder	9
Effects of acrylamide on protein degradation pathways in human liver-derived cells and the efficacy of N-acetylcysteine and curcumin	8
Co-drug of isoniazid and sulfur containing antioxidant for attenuation of hepatotoxicity and treatment of tuberculosis	8
Immunotoxic effects of force-fed ethephon on model organism Galleria mellonella (Lepidoptera: Pyralidae)	8
Sub-chronic and chronic toxicity evaluation of 7-methylxanthine: a new molecule for the treatment of myopia	8
The protective effect of herniarin on genotoxicity and apoptosis induced by cisplatin in bone marrow cells of rats	8
Cytogenetic effects of antidiabetic drug metformin	8
Protective effects of p-coumaric acid against gentamicin-induced nephrotoxicity in rats	8
Neuromodulatory and oxidative stress evaluations in African catfish Clarias gariepinus exposed to antipsychotic drug chlorpromazine	8
Protective effects of extracts of lichen Dirinaria consimilis (Stirton) D.D. Awasthi in bifenthrin- and diazinon-induced oxidative stress in rat erythrocytes in vitro	8
Lipid-lowering, anti-inflammatory, and hepatoprotective effects of isorhamnetin on acetaminophen-induced hepatotoxicity in mice	8
Safety and biological activity evaluation of Uncaria rhynchophylla ethanolic extract	8
Therapeutic effects of thymoquinone or capsaicin on acrylamide-induced reproductive toxicity in rats mediated by their effect on oxidative stress, inflammation, and tight junction integrity	8
Evaluation of the toxicological effects of favipiravir (T-705) on liver and kidney in rats: biochemical and histopathological approach	8
Diosgenin inhibits TGF-β1/Smad signaling and regulates epithelial mesenchymal transition in experimental pulmonary fibrosis	8
Hepatoprotective effect of seabuckthorn leaf-extract in lead acetate-intoxicated Wistar rats	7
Centella asiatica prevents D-galactose-Induced cognitive deficits, oxidative stress and neurodegeneration in the adult rat brain	7
Enhanced fluorescent sensing probe via PbS quantum dots functionalized with gelatin for sensitive determination of toxic bentazon in water samples	7
Ameliorating effect of rutin against diclofenac-induced cardiac injury in rats with underlying function of FABP3, MYL3, and ANP	7
Borassus flabellifer Linn haustorium methanol extract mitigates fluoride-induced apoptosis by enhancing Nrf2/Haeme oxygenase 1 –dependent glutathione metabolism in intestinal epithelial cells	7
PM2.5from diesel exhaust attenuated fisetin mediated cytoprotection in H9c2 cardiomyocytes subjected to ischemia reoxygenation by inducing mitotoxicity	7

The effects of carvedilol, metoprolol and propranolol on cisplatin-induced kidney injury	7
Morel mushroom, Morchella from Kashmir Himalaya: a potential source of therapeutically useful bioactives that possess free radical scavenging, anti-inflammatory, and arthritic edema-inhibiting	7
Ameliorative effects of hexane extract of Garcinia kola seeds Heckel (Clusiaceae) in cisplatin-induced hepatorenal toxicity in mice	7
Exacerbation of diclofenac-induced gastroenterohepatic damage by concomitant exposure to sodium fluoride in rats: protective role of luteolin	7
Acute organophosphate and carbamate pesticide poisonings – a five-year survey from the National Poison Control Center Of Serbia	7
Neurotoxic responses of rainbow trout (Oncorhynchus mykiss) exposed to fipronil: multi-biomarker approach to illuminate the mechanism in brain	7
l-Theanine ameliorates motor deficit, mitochondrial dysfunction, and neurodegeneration against chronic tramadol induced rats model of Parkinson’s disease	7
Quercetin alleviates styrene oxide-induced cytotoxicity in cortical neurons in vitro via modulation of oxidative stress and apoptosis	7
Microplastic-induced oxidative stress response in turbot and potential intake by humans	7
Ochratoxin a in breast milk in Morocco: the affecting dietary habits of the lactating mothers and the degree of exposure of newborns “CONTAMILK study”	7
Evidence of drug-induced hepatotoxicity in the Maghrebian population	7
Investigation of the genotoxic effects of patent blue V (E131) in human peripheral lymphocytes and in silico molecular docking	7
Tucumã (Astrocaryum aculeatum) extract: phytochemical characterization, acute and subacute oral toxicity studies inWistarrats	7
Protective effects of resveratrol and avocado oil against paracetamol-induced hepatotoxicity in rats	7
Cocoyam (Colocasia esculenta) modulates some parameters of testosterone propionate-induced rat model of benign prostatic hyperplasia	7
Role of cinnamon oil against acetaminophen overdose induced neurological aberrations through brain stress and cytokine upregulation in rat brain	6
MicroRNA as an early diagnostic biomarker for contrast-induced acute kidney injury	6
Subacute oral toxicology and toxicokinetics of pterostilbene, a novel Top1/Tdp1 inhibiting anti-tumor reagent	6
In silico QSAR modeling to predict the safe use of antibiotics during pregnancy	6
Modulating effect of a hydroxychalcone and a novel coumarin–chalcone hybrid against mitomycin-induced genotoxicity in somatic cells of Drosophila melanogaster	6
Anticlastogenic, antimutagenic, and cytoprotective properties ofOrthosiphon stamineusethanolic leaves extract	6
Gallic acid ameliorates busulfan-induced testicular toxicity and damage in mature rats	6
Decision tree algorithm can determine the outcome of repeated supratherapeutic ingestion (RSTI) exposure to acetaminophen: review of 4500 national poison data system cases	6
The protective effect of rutin against busulfan-induced testicular damage in adult rats	6
Antioxidant, antinociceptive, anti-inflammatory, and hepatoprotective activities of pentacyclic triterpenes isolated from Ziziphus oxyphylla Edgew	6
Tempol (4-hydroxy tempo) protects mice from cisplatin-induced acute kidney injury via modulation of expression of aquaporins and kidney injury molecule-1	6
Psoralen induces liver injuries through endoplasmic reticulum stress signaling in female mice	6
Toxicological effects of the Morinda citrifolia L. fruit extract on maternal reproduction and fetal development in rats	6
Involvement of oxidative stress and toll-like receptor-4 signaling pathways in gentamicin-induced nephrotoxicity in male Sprague Dawley rats	6
Azithromycin effects on the European sea bass (Dicentrarchus labrax) early life stages following acute and chronic exposure: Laboratory bioassays	6
3,4-Dihydroxybenzaldehyde attenuates pentachlorophenol-induced cytotoxicity, DNA damage and collapse of mitochondrial membrane potential in isolated human blood cells	6
Nano-titanium nitride causes developmental toxicity in zebrafish through oxidative stress	6
Long-term toxicity of fluoroquinolones: a comprehensive review	5
Betaine attenuates sodium arsenite-induced renal dysfunction in rats	5
Verbascoside inhibits paraquate-induced pulmonary toxicity via modulating oxidative stress, inflammation, apoptosis and DNA damage in A549 cell	5
Enniatin B induces dosage-related apoptosis or necrosis in mouse blastocysts leading to deleterious effects on embryo development	5
Ixazomib-associated cardiovascular adverse events in multiple myeloma: a systematic review and meta-analysis	5
Investigation of the effects of three different generations of fluoroquinolone derivatives on antioxidant and immunotoxic enzyme levels in different rat tissues	5
Trends of acute drug and chemical toxicities in adults and adolescents in Tehran, Iran between 2012 and 2018: a retrospective chart review	5
Nebivolol alleviates liver damage caused by methotrexate via AKT1/Hif1α/eNOS signaling	5
Protocatechuic acid protects against hepatorenal toxicities in rats exposed to Furan	5
Preventive treatment with sodium para-aminosalicylic acid inhibits manganese-induced apoptosis and inflammation via the MAPK pathway in rat thalamus	5
The effect of melatonin on testis histological changes and spermatogenesis indexes in mice following treatment with dexamethasone	5
Febuxostat, an inhibitor of xanthine oxidase, ameliorates ionizing radiation-induced lung injury by suppressing caspase-3, oxidative stress and NF-κB	5
Protective effect of Thymus munbyanus aqueous extract against 2,4-dichlorophenoxyacetic acid-induced nephrotoxicity in Wistar rats	5
Attenuation of methotrexate induced hepatotoxicity by epigallocatechin 3-gallate	5
Rutin ameliorates perfluorooctanoic acid-induced testicular injury in mice by reducing oxidative stress and improving lipid metabolism	5
Ameliorative role of inducible nitric oxide synthase inhibitors against sodium arsenite-induced renal and hepatic dysfunction in rats	5
Subacute toxicity study of the ethanolic extract of Mesua ferrea (L.) flowers in rats	5
Toxicological assessment of electronic cigarette vaping: an emerging threat to force health, readiness and resilience in the U.S. Army	5
Alpha-mangostin attenuates the apoptotic pathway of abamectin in the fetal rats’ brain by targeting pro-oxidant stimulus, catecholaminergic neurotransmitters, and transcriptional regulation of reelin	5
Exposure to pyrethroids induces behavioral impairments, neurofibrillary tangles and tau pathology in Alzheimer’s type neurodegeneration in adult Wistar rats	5
Toxicity of the herbicides used on herbicide-tolerant crops, and societal consequences of their use in France	5
Effects of prolonged subchronic benzo(α)pyrene exposure on rat liver morphology and CYP1A expression during treatment with menadione, quercetin, or tocopherol	5
Cyclophosphamide, a cancer chemotherapy drug-induced early onset of reproductive senescence and alterations in reproductive performance and their prevention in mice	4
The protective effect of chrysin against oxidative stress and organ toxicity in rats exposed to propetamphos	4
Ethyl pyruvate attenuates cisplatin-induced ovarian injury in rats via activating Nrf2 pathway	4
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats	4
Cytogenotoxic evaluation of the acetonitrile extract, citrinin and dicitrinin-A from Penicillium citrinum	4
Comparative evaluation of the effects of bisphenol derivatives on oxidative stress parameters in HepG2 cells	4
Tissue-specific toxicity of clothianidin on rainbow trout (Oncorhynchus mykiss)	4
Bromelain protects against cisplatin-induced ocular toxicity through mitigating oxidative stress and inflammation	4
Electronic cigarette aerosol increases the risk of organ dysfunction by enhancing oxidative stress and inflammation	4
Lead and lead–arsenic combined exposure induces mortality and developmental impairments in zebrafish embryos: a study using wild-caught zebrafish from Bangladesh	4
The effects of apelin-13 against cisplatin-induced nephrotoxicity in rats	4
Impact of free curcumin and curcumin nanocapsules on viability and oxidative status of neural cell lines	4
25I-NBOMe, a phenethylamine derivative, induces adverse cardiovascular effects in rodents: possible involvement of p21 (CDC42/RAC)-activated kinase 1	4
Phytochemical evaluation of Cucumis prophetarum: protective effects against carrageenan-induced prostatitis in rats	4
Carbamazepine-induced renal toxicity may be associated with oxidative stress and apoptosis in male rat	4
Curcumin mediates autophagy and apoptosis in granulosa cells: a study of integrated network pharmacology and molecular docking to elucidate toxicological mechanisms	4
Mutagenic and teratogenic toxicity evaluation of Forsythia suspensa leaves aqueous extract	4
3-Pyridinylboronic acid normalizes the effects of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in zebrafish embryos	4
D-ribose-L-cysteine modulates lead acetate-induced hematobiochemical alterations, hormonal imbalance, and ovarian toxicity in adult female Wistar rats	4
Rupatadine protects the intestinal mucosa from injury by 5-flurouracil via modulation of inflammation, apoptosis and intestinal permeability	4
Investigation of protective effect of ellagic acid in phthalates-induced reproductive damage	4
Toxic and bioaccumulative effects of zinc nanoparticle exposure to goldfish, Carassius auratus (Linnaeus, 1758)	4
Investigation into the protective effects of Hypericum Triquetrifolium Turra seed against cyclophosphamide-induced testicular injury in Sprague Dawley rats	4
Evaluation of oxidative stress biomarkers and liver and renal functional parameters in patients during treatment a mental health unit to treat alcohol dependence	4
Standardized aqueous stem bark extract of Gmelina arborea roxb. possesses nephroprotection against adriamycin-induced nephrotoxicity in Wistar rats	4
The system of self-consistent models based on quasi-SMILES as a tool to predict the potential of nano-inhibitors of human lung carcinoma cell line A549 for different experimental conditions	4

Fluvastatin alleviates doxorubicin-induced cardiac and renal toxicity in rats via regulation of oxidative stress, inflammation, and apoptosis associated genes expressions	4
The protective effects of capsaicin on oxidative damage-induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats	4
Effects of pinealectomy and crocin treatment on rats with isoproterenol-induced myocardial infarction	4
Effects of the copper oxide nanoparticles (CuO NPs) onGalleria mellonellahemocytes	4
Protective effect of dapagliflozin against cyclosporine A-induced nephrotoxicity	4
Cumulative effects of manganese nanoparticle and radiofrequency radiation in male Wistar rats	3
The preventive effects of Centaurea maroccana Ball. extract against oxidative stress induced by cisplatin in mice brains: in vitro and in vivo studies	3
Long term integrated biomarker responses in freshwater African catfish Clarias gariepinus exposed to a new brand of herbicide fluazifop-p-butyl	3
Hepatoprotective effect of Sophora moorcroftiana (Benth.) Benth.Ex baker seeds in vivo and in vitro	3
Distribution, metabolism, excretion, and toxicity of implanted silver: a review	3
Methanol fraction ofFicus mucoso(welw) prevents iron-induced oxidative damage and alters mitochondrial dysfunction inDrosophila melanogaster	3
Lagerstroemia speciosa (L.) Pers., ethanolic leaves extract attenuates dapsone-induced liver inflammation in rats	3
Evaluation of the non-clinical toxicity of an antiparasitic agent: diminazene aceturate	3
Pinealectomy and melatonin administration in rats: their effects on pulmonary edema induced by α-naphthylthiourea	3
Hepatoprotective effects of norgalanthamine on carbon tetrachloride induced-hepatotoxicity in mice	3
Evaluation of the protective effects ofGanoderma applanatumagainst doxorubicin-induced toxicity in Dalton’s Lymphoma Ascites (DLA) bearing mice	3
A study on Wistar Albino rats: investigating protective role of ramelteon on liver damage caused by methotrexate	3
Eucalyptol alleviates cisplatin-induced kidney damage in rats	3
Biochemical and histopathological analysis after sub-chronic administration of oxyresveratrol in Wistar rats	3
Nephroprotective effect of persimmon leaves (Diospyros kaki L.f.) against CCl4-induced renal toxicity in Swiss Albino rats	3
Physiological and histopathological alterations in male Swiss mice after exposure to titanium dioxide (anatase) and zinc oxide nanoparticles and their binary mixture	3
Influence of zinc oxide nanoparticles (ZnO NPs) on the hemocyte count and hemocyte-mediated immune responses of the Greater Wax Moth Galleria mellonella (Lepidoptera: Pyralidae)	3
Phytochemical composition, cytotoxicity, antioxidant and antimicrobial responses of Lavandula dentata L. grown under different levels of heavy metals stress condition	3
Three-dimensional (3D) cell culture studies: a review of the field of toxicology	3
In vitro cytogenotoxic and mutagenic effects of Commiphora myrrha essential oil	3
Modulatory effect of myricitrin against chromosome instability and cytostasis induced by bleomycin and oxaliplatin in CHO-K1 cells	3
Comparative study of the genotoxic activity of Artemisia vulgaris L. and Artemisia alba Turra extracts in vitro	3
The effects of minocycline in improving of methamphetamine withdrawal syndrome in male mice	3
Effect of simultaneous coffee/caffeine and ethanol administration on sperm quality and reproductive hormones: an experimental study in Sprague Dawley rats	3
Synthetic pyrethroids common metabolite 3-phenoxybenzoic acid induces caspase-3 and Bcl-2 mediated apoptosis in human hepatocyte cells	3
Inhibition of methotrexate induced toxicity in the adult rat spleen by adalimumab	3
Virgin coconut oil complements with its polyphenol components mitigate sodium fluoride toxicity in vitro and in vivo	3
Mechanisms underlying citrinin-induced toxicity via oxidative stress and apoptosis-mediated by mitochondrial-dependent pathway in SH-SY5Y cells	3
Genotoxic and mutagenic potential of 7-methylxanthine: an investigational drug molecule for the treatment of myopia	3
Hepatoprotective effects of a chemically-characterized extract from artichoke (Cynara scolymus L.) against AFB1-induced toxicity in rats	3
Exogenous glutathione protects against gentamicin-induced acute kidney injury by inhibiting NF-κB pathway, oxidative stress, and apoptosis and regulating PCNA	3
Hot-processed virgin coconut oil abrogates cisplatin-induced nephrotoxicity by restoring redox balance in rats compared to fermentation-processed virgin coconut oil	3
Evaluation of 28-day repeated oral dose toxicity of aluminum chloride in rats	3
Manganese mitigates against hepatorenal oxidative stress, inflammation and caspase-3 activation in rats exposed to hexachlorobenzene	3
Non-permitted food colorants induced neurotoxicity in cerebellum of rat brain	3
Perfluorooctane sulfonate (PFOS) triggers migration and invasion of esophageal squamous cell carcinoma cells via regulation of Zeb1	3
Protective effects of lotus plumule ethanol extracts on bleomycin-induced pulmonary fibrosis in mice	3
Methanol extracts of Teucrium arduini L. and Teucrium flavum L. induce protective effect against mitomycin C in human lymphocytes in vitro	2
Repeated dose of meloxicam induces genotoxicity and histopathological changes in cardiac tissue of mice	2
Ninety-day oral toxicological profiling of Kolaviron (an extract of Garcinia kola) in male and female rats	2
Acute toxicity studies and protective effects of Cinnamon cassia bark extract in streptozotocin-induced diabetic rats	2
Short-term toxicity study of 1-aminobenzotraizole, a CYP inhibitor, in Wistar rats	2
Protective effects of royal jelly and Echinacea against moxifloxacin-induced renal and hepatic injury in rats	2
Anti-ischemic drug trimetazidine blocks mercury nephrotoxicity by suppressing renal redox imbalance, inflammatory stress and caspase-dependent apoptosis in rats	2
Long-term reproductive effects of benzo(a)pyrene at environmentally relevant dose on juvenile female rats	2
Acute and subacute (28 days) oral toxicity studies of tucum almond oil (Bactris Setosa Mart.) in mice	2
Caffeic acid and ferulic acid can improve toxicological damage caused by iron overload mediated by carbonic anhydrase inhibition	2
In vitro hematotoxicity of Vernonanthura polyanthes leaf aqueous extract and its fractions	2
Preclinical safety profile of RC88-ADC：a novel mesothelin-targeted antibody conjugated with Monomethyl auristatin E	2
Adverse effects of textile dyes on antioxidant enzymes and cholinesterase activities in Drosophila melanogaster (Oregon R+)	2
Assessment of the genotoxic effects of antihypertensive drug active ingredient indapamide in human lymphocytes	2
Anticonvulsant effectiveness of scopolamine against soman-induced seizures in African green monkeys	2
Modulatory activities of polyphenols on crude acetylene-induced cardiac and hepatic dysfunctions in a rat model	2
Nω-nitro-L-arginine, a nitric oxide synthase inhibitor, attenuates nickel-induced neurotoxicity	2
The administration of methyl and butyl parabens interferes with the enzymatic antioxidant system and induces genotoxicity in rat testis: possible relation to male infertility	2
Alterations in gills and intestine of Danio rerio after exposure to acaricide yoksorrun-5EC (hexythiazox): histopathologic and morphometric evaluation	2
Neutralization of iron oxide magnetic nanoparticle aquatoxicity on Oncorhynchus mykiss via supplementation with ulexite	2
Ulva fasciata, a green alga, attenuates the kidney and liver dysfunctions in rats induced by acetaminophen	2
MiADMSA abrogates sodium tungstate-induced oxidative stress in rats	2
Investigation of the phytochemical composition and remedial effects of southern grape hyacinth (Muscari neglectum Guss. ex Ten.) plant extract against carbon tetrachloride-induced oxidative str	2
Assessment of imidacloprid induced genotoxicity in Pethia conchonius (Rosy barb), a common freshwater fish of India	2
Pre-imaginal exposure to mancozeb induces morphological and behavioral deficits and oxidative damage in Drosophila melanogaster	2
Sub-chronic toxicity of an aqueous extract of Epimedium sagittatum (Sieb. Et Zucc.) Maxim. in rats	2
Temporal analysis of paracetamol-induced hepatotoxicity	2
Evaluating Water bitter leaf (Struchium sparganophora) and Scent Leaf (Ocimum gratissimum)extracts as sources of nutraceuticals against manganese-induced toxicity in fruit fly model	2
Hypericin, a medicinal compound from St. John’s Wort, inhibits genotoxicity induced by mutagenic agents in V79 cells	2
Analysis of suppressive effects of pesticide triazophos on leucocyte immune responses in a teleost,Channa Punctatus	2
Identification and genotoxicity evaluation of potential impurities in rabeprazole sodium using in silico and in vitro analyses	2
Investigation of genotoxic effects of rhododendron honey using three mammalian bioassaysin vivo	2
Real-time monitoring of cellular oxidative stress during aerosol sampling: a proof of concept study	2
Liver function alterations among workers in the shoe industry due to combined low-level exposure to organic solvents	2
Determination of preclinical safety of oil obtained from Pachira aquatica Aublet (Malvaceae) seeds: histopathological, biochemical, hematological, and genetic toxicity studies in rats	2
Renal tubular response to titanium dioxide nanoparticles exposure	2
Flavonoid-rich fraction of Lasianthera africana leaves alleviates hepatotoxicity induced by carbon tetrachloride in Wistar rats	2
The molecular interaction of human anti-apoptotic proteins andin silicoADMET, drug-likeness and toxicity computation of N-cyclohexylmethacrylamide	2
Dexamethasone increases renal free fatty acids and xanthine oxidase activity in female rats: could there be any gestational impact?	2
Comparative evaluation of natural and artificial sweeteners from DNA damage, oxidative stress, apoptosis, to development using Drosophila melanogaster	2
Further insights into the impact of rebamipide on gentamicin-induced nephrotoxicity in rats: modulation of SIRT1 and β-catenin/cyclin D1 pathways	2
Sulfoxaflor insecticide exhibits cytotoxic or genotoxic and apoptotic potential via oxidative stress-associated DNA damage in human blood lymphocytes cell cultures	2
In vitro antibacterial and anti-inflammatory effects of Anacardium occidentale L. extracts and their toxicity on PBMCs and zebrafish embryos	2
Synergistic hepatoprotective effects of ω-3 and ω-6 fatty acids from Indian flax and sesame seed oils against CCl4-induced oxidative stress-mediated liver damage in rats	2
In silico, in vitro, and in vivo investigation of antioxidant potential and toxicity of ethyl ferulate	2
Interactive effect of carbendazim and imidacloprid on buffalo bone marrow derived mesenchymal stem cells: oxidative stress, cytotoxicity and genotoxicity	2
Genotoxic effects of drospirenone and ethinylestradiol in human breast cells (in vitro) and bone marrow cells of female mice (in vivo)	2
Kigelia africana (Lam.) Benth leaf extract inhibits rat brain and liver mitochondrial membrane permeability transition pore opening	2
Intestinal epithelial damage due to herbal compounds – an in vitro study	2
Genotoxic effects of gadobutrol and gadoversetamide active substances used in magnetic resonance imaging in human peripheral lymphocytes in vitro	2
Acute and subacute oral toxicity of artemisinin-hydroxychloroquine sulfate tablets in beagle dogs	2
The PERK/ATF4/CHOP signaling branch of the unfolded protein response mediates cisplatin-induced ototoxicity in hair cells	2
Hepatic susceptibility to oxidative damage after repeated concomitant exposure to aspartame and aflatoxin B1 in rats	2