Drug and Chemical Toxicology

Papers
(The median citation count of Drug and Chemical Toxicology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Chemical characterization of tobacco-free “modern” oral nicotine pouches and their position on the toxicant and risk continuums54
Rifampicin decreases neuroinflammation to maintain mitochondrial function and calcium homeostasis in rotenone-treated zebrafish22
Linalool exhibits therapeutic and protective effects in a rat model of doxorubicin-induced kidney injury by modulating oxidative stress20
Ameliorative effect of gallic acid on cisplatin-induced ovarian toxicity in rats20
Hepatoprotective effect of Ginkgo biloba extract against methotrexate-induced hepatotoxicity via targeting STAT3/miRNA-21 axis19
Acrylamide induces intrinsic apoptosis and inhibits protective autophagy via the ROS mediated mitochondrial dysfunction pathway in U87-MG cells16
Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats16
The comparison of the effect of Origanum vulgare L. extract and vitamin C on the gentamycin-induced nephrotoxicity in rats15
Melatonin modulates copper-induced anxiety-like, depression-like and memory impairments by acting on hippocampal oxidative stress in rat15
The outbreak of methanol intoxication during COVID-19 pandemic: prevalence of brain lesions and its predisposing factors14
Glabridin attenuates paracetamol-induced liver injury in mice via CYP2E1-mediated inhibition of oxidative stress13
Effect of carnosic acid on acrylamide induced neurotoxicity: in vivo and in vitro experiments13
Linalool reverses benzene-induced cytotoxicity, oxidative stress and lysosomal/mitochondrial damages in human lymphocytes13
Borassus flabellifer haustorium extract prevents pro-oxidant mediated cell death and LPS-induced inflammation13
L-Carnitine alleviates hepatic and renal mitochondrial-dependent apoptotic progression induced by letrozole in female rats through modulation of Nrf-2, Cyt c and CASP-3 signaling13
A comparison of cell death mechanisms of antioxidants, butylated hydroxyanisole and butylated hydroxytoluene13
Role of aluminum exposure on Alzheimer’s disease and related glycogen synthase kinase pathway13
Neurotoxicity of poly(propylene imine) glycodendrimers13
Morphine attenuates neurotoxic effects of MPTP in zebrafish embryos by regulating oxidant/antioxidant balance and acetylcholinesterase activity12
Ellagic acid alleviates clozapine‑induced oxidative stress and mitochondrial dysfunction in cardiomyocytes12
Effects of burnt tire-ash on Na+/K+, Ca2+-ATPase, serum immunoglobulin and brain acetylcholinesterase activities in clarias gariepinus (Burchell, 1822)11
l -Theanine ameliorates motor deficit, mitochondrial dysfunction, and neurodegeneration against chronic tramadol induced rats model of Parkinson’s disease11
The effect of sulfamethoxazole on oxidative stress indices in zebrafish (Danio rerio)11
Effects of acrylamide on protein degradation pathways in human liver-derived cells and the efficacy ofN-acetylcysteine and curcumin11
The protective effects of vitamins A, C, and E on zinc oxide nanoparticles (ZnO NPs)-induced liver oxidative stress in male Wistar rats11
Lipid-lowering, anti-inflammatory, and hepatoprotective effects of isorhamnetin on acetaminophen-induced hepatotoxicity in mice11
Microplastic-induced oxidative stress response in turbot and potential intake by humans10
Investigation of the genotoxic effects of patent blue V (E131) in human peripheral lymphocytes and in silico molecular docking10
Gallic acid ameliorates busulfan-induced testicular toxicity and damage in mature rats10
The impact of filtered water-pipe smoke on healthy versus cancer cells and their neurodegenerative role on AMPA receptor10
Neurotoxic responses of rainbow trout ( Oncorhynchus mykiss ) exposed to fipronil: multi-biomarker approach to illuminate the mechanism in brain10
Effects of ellagic acid in the testes of streptozotocin induced diabetic rats10
Enhanced fluorescent sensing probe via PbS quantum dots functionalized with gelatin for sensitive determination of toxic bentazon in water samples9
Attenuation of methotrexate induced hepatotoxicity by epigallocatechin 3-gallate9
The protective effect of herniarin on genotoxicity and apoptosis induced by cisplatin in bone marrow cells of rats9
Therapeutic effects of thymoquinone or capsaicin on acrylamide-induced reproductive toxicity in rats mediated by their effect on oxidative stress, inflammation, and tight junction integrity9
Toxicological effects of the Morinda citrifolia L. fruit extract on maternal reproduction and fetal development in rats9
Antiandrogen enzalutamide induced genetic, cellular, and hepatic damages: amelioration by triterpene Lupeol9
Cytogenetic effects of antidiabetic drug metformin9
Cocoyam ( Colocasia esculenta ) modulates some parameters of testosterone propionate-induced rat model of benign prostatic hyperplasia9
Evaluation of the toxicological effects of favipiravir (T-705) on liver and kidney in rats: biochemical and histopathological approach9
Verbascoside inhibits paraquate-induced pulmonary toxicity via modulating oxidative stress, inflammation, apoptosis and DNA damage in A549 cell9
The role of ginger’s extract and N-acetylcysteine against docetaxel-induced oxidative stress and genetic disorder9
Salvianolic acid A suppresses CCl4-induced liver fibrosis through regulating the Nrf2/HO-1, NF-κB/IκBα, p38 MAPK, and JAK1/STAT3 signaling pathways9
Protective effects ofp-coumaric acid against gentamicin-induced nephrotoxicity in rats8
Immunotoxic effects of force-fed ethephon on model organism Galleria mellonella (Lepidoptera: Pyralidae)8
Borassus flabellifer Linn haustorium methanol extract mitigates fluoride-induced apoptosis by enhancing Nrf2/Haeme oxygenase 1 –dependent glutathione metabolism in intestinal epithe8
Protective effects of resveratrol and avocado oil against paracetamol-induced hepatotoxicity in rats8
Involvement of oxidative stress and toll-like receptor-4 signaling pathways in gentamicin-induced nephrotoxicity in male Sprague Dawley rats8
Trends of acute drug and chemical toxicities in adults and adolescents in Tehran, Iran between 2012 and 2018: a retrospective chart review8
Preventive treatment with sodium para-aminosalicylic acid inhibits manganese-induced apoptosis and inflammation via the MAPK pathway in rat thalamus8
Tissue-specific toxicity of clothianidin on rainbow trout (Oncorhynchus mykiss)8
Morel mushroom, Morchella from Kashmir Himalaya: a potential source of therapeutically useful bioactives that possess free radical scavenging, anti-inflammatory, and art8
Subacute oral toxicology and toxicokinetics of pterostilbene, a novel Top1/Tdp1 inhibiting anti-tumor reagent8
In silico QSAR modeling to predict the safe use of antibiotics during pregnancy8
Quercetin alleviates styrene oxide-induced cytotoxicity in cortical neuronsin vitrovia modulation of oxidative stress and apoptosis8
Acute organophosphate and carbamate pesticide poisonings – a five-year survey from the National Poison Control Center Of Serbia7
PM2.5from diesel exhaust attenuated fisetin mediated cytoprotection in H9c2 cardiomyocytes subjected to ischemia reoxygenation by inducing mitotoxicity7
The effects of carvedilol, metoprolol and propranolol on cisplatin-induced kidney injury7
Toxic and bioaccumulative effects of zinc nanoparticle exposure to goldfish, Carassius auratus (Linnaeus, 1758)7
Nano-titanium nitride causes developmental toxicity in zebrafish through oxidative stress7
Psoralen induces liver injuries through endoplasmic reticulum stress signaling in female mice7
MicroRNA as an early diagnostic biomarker for contrast-induced acute kidney injury7
Antioxidant, antinociceptive, anti-inflammatory, and hepatoprotective activities of pentacyclic triterpenes isolated from Ziziphus oxyphylla Edgew7
Alpha-mangostin attenuates the apoptotic pathway of abamectin in the fetal rats’ brain by targeting pro-oxidant stimulus, catecholaminergic neurotransmitters, and transcriptional regulation of reelin 7
Ameliorating effect of rutin against diclofenac-induced cardiac injury in rats with underlying function of FABP3, MYL3, and ANP6
Mutagenic and teratogenic toxicity evaluation of Forsythia suspensa leaves aqueous extract6
The effects of minocycline in improving of methamphetamine withdrawal syndrome in male mice6
Lead and lead–arsenic combined exposure induces mortality and developmental impairments in zebrafish embryos: a study using wild-caught zebrafish from Bangladesh6
Decision tree algorithm can determine the outcome of repeated supratherapeutic ingestion (RSTI) exposure to acetaminophen: review of 4500 national poison data system cases6
Nebivolol alleviates liver damage caused by methotrexate via AKT1/Hif1α/eNOS signaling6
Protocatechuic acid protects against hepatorenal toxicities in rats exposed to Furan6
Anti-ischemic drug trimetazidine blocks mercury nephrotoxicity by suppressing renal redox imbalance, inflammatory stress and caspase-dependent apoptosis in rats6
Bromelain protects against cisplatin-induced ocular toxicity through mitigating oxidative stress and inflammation6
Investigation of the effects of three different generations of fluoroquinolone derivatives on antioxidant and immunotoxic enzyme levels in different rat tissues6
Investigation of protective effect of ellagic acid in phthalates-induced reproductive damage6
Betaine attenuates sodium arsenite-induced renal dysfunction in rats6
Carbamazepine-induced renal toxicity may be associated with oxidative stress and apoptosis in male rat6
The effect of melatonin on testis histological changes and spermatogenesis indexes in mice following treatment with dexamethasone6
Comparative cytotoxicity induced by parabens and their halogenated byproducts in human and fish cell lines6
Rutin ameliorates perfluorooctanoic acid-induced testicular injury in mice by reducing oxidative stress and improving lipid metabolism6
Febuxostat, an inhibitor of xanthine oxidase, ameliorates ionizing radiation-induced lung injury by suppressing caspase-3, oxidative stress and NF-κB5
Effects of prolonged subchronic benzo(α)pyrene exposure on rat liver morphology and CYP1A expression during treatment with menadione, quercetin, or tocopherol5
Investigation into the protective effects of Hypericum Triquetrifolium Turra seed against cyclophosphamide-induced testicular injury in Sprague Dawley rats5
Genotoxic and mutagenic potential of 7-methylxanthine: an investigational drug molecule for the treatment of myopia5
Comparative evaluation of the effects of bisphenol derivatives on oxidative stress parameters in HepG2 cells5
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats5
Fluvastatin alleviates doxorubicin-induced cardiac and renal toxicity in rats via regulation of oxidative stress, inflammation, and apoptosis associated genes expressions5
Effects of the copper oxide nanoparticles (CuO NPs) onGalleria mellonellahemocytes5
D-ribose-L-cysteine modulates lead acetate-induced hematobiochemical alterations, hormonal imbalance, and ovarian toxicity in adult female Wistar rats5
Long-term reproductive effects of benzo(a)pyrene at environmentally relevant dose on juvenile female rats5
The protective effect of chrysin against oxidative stress and organ toxicity in rats exposed to propetamphos5
Long-term toxicity of fluoroquinolones: a comprehensive review5
Subacute toxicity study of the ethanolic extract of Mesua ferrea (L.) flowers in rats5
Distribution, metabolism, excretion, and toxicity of implanted silver: a review5
Electronic cigarette aerosol increases the risk of organ dysfunction by enhancing oxidative stress and inflammation5
Eucalyptol alleviates cisplatin-induced kidney damage in rats5
Biochemical and histopathological analysis after sub-chronic administration of oxyresveratrol in Wistar rats5
Acute and sub-acute oral toxicity assessment of 5-hydroxy-1,4-naphthoquinone in mice5
Hesperidin via maintenance of mitochondrial function and antioxidant activity protects lithium toxicity in rat heart isolated mitochondria5
Toxicological assessment of electronic cigarette vaping: an emerging threat to force health, readiness and resilience in the U.S. Army5
The system of self-consistent models based on quasi-SMILES as a tool to predict the potential of nano-inhibitors of human lung carcinoma cell line A549 for different experimental conditions5
Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems5
Lagerstroemia speciosa (L.) Pers., ethanolic leaves extract attenuates dapsone-induced liver inflammation in rats4
Non-permitted food colorants induced neurotoxicity in cerebellum of rat brain4
Phycocyanin improved alcohol-induced hepatorenal toxicity and behavior impairment in Wistar rats4
Investigation of the phytochemical composition and remedial effects of southern grape hyacinth (Muscari neglectum Guss. ex Ten.) plant extract against carbon tetrachloride-induced oxidative str4
In silico, in vitro, and in vivo investigation of antioxidant potential and toxicity of ethyl ferulate4
Mechanisms underlying citrinin-induced toxicity via oxidative stress and apoptosis-mediated by mitochondrial-dependent pathway in SH-SY5Y cells4
Influence of zinc oxide nanoparticles (ZnO NPs) on the hemocyte count and hemocyte-mediated immune responses of the Greater Wax Moth Galleria mellonella (Lepidoptera: Pyralidae)4
TiO 2 nanoparticles: green synthesis, characterization, and investigation of antimicrobial properties, and developmental toxicity in zebrafish ( Danio4
Exogenous glutathione protects against gentamicin-induced acute kidney injury by inhibiting NF-κB pathway, oxidative stress, and apoptosis and regulating PCNA4
Hepatoprotective effects of a chemically-characterized extract from artichoke (Cynara scolymus L.) against AFB1-induced toxicity in rats4
Analysis of suppressive effects of pesticide triazophos on leucocyte immune responses in a teleost,Channa Punctatus4
Further insights into the impact of rebamipide on gentamicin-induced nephrotoxicity in rats: modulation of SIRT1 and β-catenin/cyclin D1 pathways4
Effects of pinealectomy and crocin treatment on rats with isoproterenol-induced myocardial infarction4
Protective effects of lotus plumule ethanol extracts on bleomycin-induced pulmonary fibrosis in mice4
The effects of apelin-13 against cisplatin-induced nephrotoxicity in rats4
Impact of free curcumin and curcumin nanocapsules on viability and oxidative status of neural cell lines4
Ameliorative role of inducible nitric oxide synthase inhibitors against sodium arsenite-induced renal and hepatic dysfunction in rats4
The molecular interaction of human anti-apoptotic proteins and in silico ADMET, drug-likeness and toxicity computation of N-cyclohexylmethacrylamide4
MiADMSA abrogates sodium tungstate-induced oxidative stress in rats4
In vitro cytogenotoxic and mutagenic effects of Commiphora myrrha essential oil4
Interactive effect of carbendazim and imidacloprid on buffalo bone marrow derived mesenchymal stem cells: oxidative stress, cytotoxicity and genotoxicity4
A study on Wistar Albino rats: investigating protective role of ramelteon on liver damage caused by methotrexate4
Rupatadine protects the intestinal mucosa from injury by 5-flurouracil via modulation of inflammation, apoptosis and intestinal permeability4
Synthetic pyrethroids common metabolite 3-phenoxybenzoic acid induces caspase-3 and Bcl-2 mediated apoptosis in human hepatocyte cells4
The preventive effects of Centaurea maroccana Ball. extract against oxidative stress induced by cisplatin in mice brains: in vitro and in vivo studies4
A comparative study on the sensitivity of selected freshwater fishes against triclosan exposure4
Ethyl pyruvate attenuates cisplatin-induced ovarian injury in rats via activating Nrf2 pathway4
Curcumin mediates autophagy and apoptosis in granulosa cells: a study of integrated network pharmacology and molecular docking to elucidate toxicological mechanisms4
Sub-chronic toxicity of an aqueous extract of Epimedium sagittatum (Sieb. Et Zucc.) Maxim. in rats4
The PERK/ATF4/CHOP signaling branch of the unfolded protein response mediates cisplatin-induced ototoxicity in hair cells3
Virgin coconut oil complements with its polyphenol components mitigate sodium fluoride toxicityin vitroandin vivo3
Comparative study of the genotoxic activity of Artemisia vulgaris L. and Artemisia alba Turra extracts in vitro3
Pre-imaginal exposure to mancozeb induces morphological and behavioral deficits and oxidative damage in Drosophila melanogaster3
Is a non-cytotoxic and non-genotoxic novel bioinspired dipeptide structure synthesis possible for theragnostic applications?3
Nephroprotective effect of persimmon leaves (Diospyros kaki L.f.) against CCl4-induced renal toxicity in Swiss Albino rats3
Combination of metformin and sub-therapeutic dose of valproic acid prevent valproic acid-induced toxicity in animal model of epilepsy3
Identification and genotoxicity evaluation of potential impurities in rabeprazole sodium using in silico and in vitro analyses3
In vitro glucuronidation of bisphenol A in liver and intestinal microsomes: interspecies differences in humans and laboratory animals3
The administration of methyl and butyl parabens interferes with the enzymatic antioxidant system and induces genotoxicity in rat testis: possible relation to male infertility3
Neutralization of iron oxide magnetic nanoparticle aquatoxicity on Oncorhynchus mykiss via supplementation with ulexite3
Modulatory effect of myricitrin against chromosome instability and cytostasis induced by bleomycin and oxaliplatin in CHO-K1 cells3
Assessment of imidacloprid induced genotoxicity in Pethia conchonius (Rosy barb), a common freshwater fish of India3
Acute toxicity studies and protective effects of Cinnamon cassia bark extract in streptozotocin-induced diabetic rats3
Effects of taxifolin on tramadol-induced oxidative and inflammatory liver injury in rats: an experimental study3
Comparative analysis of the detrimental in vitro effects of three fusariotoxins on the selected structural and functional characteristics of rabbit spermatozoa3
Changes in hormones, Leukocyte Telomere Length (LTL), and p16INK4a expression in SM-exposed individuals in favor of the cellular senescence3
Effect of chlorpyrifos on some biochemical changes in Cyprinus carpio: the protective effect of ellagic acid3
Caffeic acid and ferulic acid can improve toxicological damage caused by iron overload mediated by carbonic anhydrase inhibition3
Perfluorooctane sulfonate (PFOS) triggers migration and invasion of esophageal squamous cell carcinoma cells via regulation of Zeb13
Long term integrated biomarker responses in freshwater African catfish Clarias gariepinus exposed to a new brand of herbicide fluazifop-p-butyl3
Protective effects of a polyherbal medicine, Majoon Suranjan against bisphenol-A induced genetic, oxidative and tissue damages3
Hepatoprotective effect of Sophora moorcroftiana (Benth.) Benth.Ex baker seeds in vivo and in vitro3
Pentoxifylline inhibits phosgene-induced lung injury via improving hypoxia3
Evaluation of the non-clinical toxicity of an antiparasitic agent: diminazene aceturate3
Renal tubular response to titanium dioxide nanoparticles exposure3
Content of potentially toxic elements (PTEs) in coffee and coffee-based products: a meta-analysis study, Systematic review, and health risk assessment3
Phytochemical composition, cytotoxicity, antioxidant and antimicrobial responses of Lavandula dentata L. grown under different levels of heavy metals stress condition3
Effect ofMoringa oleiferaleaf extract on valproate-induced oxidative damage in muscle3
Short-term toxicity study of 1-aminobenzotraizole, a CYP inhibitor, in Wistar rats3
Anticonvulsant effectiveness of scopolamine against soman-induced seizures in African green monkeys3
Protective effects of cerebrolysin against chemotherapy (carmustine) induced cognitive impairment in Albino mice3
The protective effects of capsaicin on oxidative damage-induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats3
In vitro antibacterial and anti-inflammatory effects of Anacardium occidentale L. extracts and their toxicity on PBMCs and zebrafish embryos3
Pinealectomy and melatonin administration in rats: their effects on pulmonary edema induced by α-naphthylthiourea3
Chronic intraperitoneal injection of polyethylene glycol 200 in mice induces hippocampal neuroinflammation3
Determination of preclinical safety of oil obtained fromPachira aquaticaAublet (Malvaceae) seeds: histopathological, biochemical, hematological, and genetic toxicity studies in rats3
Preclinical safety profile of RC88-ADC:a novel mesothelin-targeted antibody conjugated with Monomethyl auristatin E3
The ameliorative effect of methanol extract of Ricinodendron heudelotii (Baill.) leaves on paracetamol-induced hepatotoxicity in Wistar rats3
Three-dimensional (3D) cell culture studies: a review of the field of toxicology3
Methanol fraction ofFicus mucoso(welw) prevents iron-induced oxidative damage and alters mitochondrial dysfunction inDrosophila melanogaster3
Acute and 13 weeks subchronic toxicological evaluation of the flavonoid-rich extract of Sophora flavescens3
Manganese mitigates against hepatorenal oxidative stress, inflammation and caspase-3 activation in rats exposed to hexachlorobenzene3
Inhibition of methotrexate induced toxicity in the adult rat spleen by adalimumab3
Protective role of resveratrol and apigenin against toxic effects of bisphenol a in rat salivary gland3
Pelargonidin ameliorates reserpine-induced neuronal mitochondrial dysfunction and apoptotic cascade: a comparative in vivo study2
Effect of chronic alcohol consumption on myocardial apoptosis in the rat model of isoproterenol-induced myocardial injury and investigation on the cardioprotective role of calpain inhibitor 12
Investigation of genotoxic effects of rhododendron honey using three mammalian bioassays in vivo2
The effect of glycine on oxidative stress, inflammation and renin-angiotensin system in kidneys and aorta of cyclosporine-administered rats2
Hepatoprotective effects of norgalanthamine on carbon tetrachloride induced-hepatotoxicity in mice2
Effects of acetaminophen exposure on behavior and erythrocyte nuclear morphology of juvenile Oreochromis niloticus2
Protective effects of perindopril against indomethacin-induced gastric mucosal damage through modulation of DDAH-1/ADMA and ACE-2/ANG-(1-7) signaling pathways2
Liver function alterations among workers in the shoe industry due to combined low-level exposure to organic solvents2
Assessment of the genotoxic effects of antihypertensive drug active ingredient indapamide in human lymphocytes2
Hepatic susceptibility to oxidative damage after repeated concomitant exposure to aspartame and aflatoxin B1 in rats2
Prenatal exposure of bonny light crude oil induces embryotoxicity, impaired cognitive functions and cortico-hippocampal neurodegeneration on fetal outcomes of pregnant sprague-dawley rats2
Flavonoid-rich fraction of Lasianthera africana leaves alleviates hepatotoxicity induced by carbon tetrachloride in Wistar rats2
The effect of preconditioning agents on cardiotoxicity and neurotoxicity of carbon monoxide poisoning in animal studies: a systematic review2
Toxicity assessment of watermelon seed supplemented diet in rats2
Mechanistic study of copper oxide, zinc oxide, cadmium oxide, and silver nanoparticles-mediated toxicity on the probiotic Lactobacillus reuteri2
Alterations in gills and intestine of Danio rerio after exposure to acaricide yoksorrun-5EC (hexythiazox): histopathologic and morphometric evaluation2
Comparative evaluation of natural and artificial sweeteners from DNA damage, oxidative stress, apoptosis, to development using Drosophila melanogaster2
Protective effects of a chemically characterized extract fromsolanum torvumleaves on acetaminophen-induced liver injury2
Ninety-day oral toxicological profiling of Kolaviron (an extract of Garcinia kola) in male and female rats2
Protective effect of dapagliflozin against cyclosporine A-induced nephrotoxicity2
Assessment of Toxicity and Wound Healing Activity of Selaginella Bryopteris Extract2
Temporal analysis of paracetamol-induced hepatotoxicity2
N ω -nitro-L-arginine, a nitric oxide synthase inhibitor, attenuates nickel-induced neurotoxicity2
Evaluation of immunological adjuvant activities of saponin rich fraction from the fruits of Asparagus adscendens Roxb. with less adverse reactions2
Estimating the impact of drug addiction causes heart damage2
Chlorogenic acid attenuates cisplatin-induced ovarian injury in rats2
Effect of Salvia officinalis aqueous infusion on copper sulfate-induced inflammatory response and oxidative stress imbalance in mice liver and kidney2
Evaluating Water bitter leaf (Struchium sparganophora) and Scent Leaf (Ocimum gratissimum)extracts as sources of nutraceuticals against manganese-induced toxicity in fruit fly model2
Intestinal epithelial damage due to herbal compounds – an in vitro study2
Both acute glyphosate and the aminomethylphosphonic acid intoxication decreased the acetylcholinesterase activity in rat hippocampus, prefrontal cortex and gastrocnemius muscle2
A dual-acting aldose reductase inhibitor impedes oxidative and carbonyl stress in tissues of fructose- and streptozotocin-induced rats: comparison with antioxidant stobadine2
Computational modeling ( in silico ) methods combined with ecotoxicological experiments ( in vivo ) to predict the environmental risks of 2
Pesticides analysis in alternative biological matrices2
Protective effects of royal jelly and Echinacea against moxifloxacin-induced renal and hepatic injury in rats2
Screening the immunotoxicity of different food preservative agents on the model organism Galleria mellonella L. (Lepidoptera: Pyralidae) larvae2
Sulfoxaflor insecticide exhibits cytotoxic or genotoxic and apoptotic potential via oxidative stress-associated DNA damage in human blood lymphocytes cell cultures2
Study of cardioprotective activity of the methanolic extract of the aerial parts of Bauhinia madagascariensis compared to Bauhinia purpurea 2
D-ribose-L-cysteine exhibits neuroprotective activity through inhibition of oxido-behavioral dysfunctions and modulated activities of neurotransmitters in the cerebellum of Juvenile mice exposed to et2
Toxicity of commercial and pure forms of three nonsteroidal anti-inflammatory drugs in Xenopus laevis embryos before and after ozonation2
Synergistic hepatoprotective effects of ω-3 and ω-6 fatty acids from Indian flax and sesame seed oils against CCl 4 -induced oxidative stress-mediated liver damage i2
Treatment with human umbilical cord blood serum in a gentamicin-induced nephrotoxicity model in rats2
Kigelia africana(Lam.) Benth leaf extract inhibits rat brain and liver mitochondrial membrane permeability transition pore opening2
28-day repeated dose toxicological evaluation of Coronil in Sprague Dawley rats: Behavioral, hematological, biochemical and histopathological assessments under GLP compliance2
Rosuvastatin exposure in female Wistar rats alters uterine contractility and do not show evident (anti)estrogenic effects2
Evaluation of antifungal activity, mechanisms of action and toxicological profile of the synthetic amide 2-chloro- N -phenylacetamide2
Genotoxic effects of drospirenone and ethinylestradiol in human breast cells (in vitro) and bone marrow cells of female mice (in vivo)2
Effects of electrospun fiber curcumin on bisphenol A exposed Caco-2 cells2
Modulatory activities of polyphenols on crude acetylene-induced cardiac and hepatic dysfunctions in a rat model2
Genotoxic effects of gadobutrol and gadoversetamide active substances used in magnetic resonance imaging in human peripheral lymphocytesin vitro2
Pterocarpus mildbraedii leaf extract ebbs propanil-induced oxidative and apoptotic damage in the liver of rats2
Risk factors associated with warfarin overdose and complications related to warfarin overdose in the emergency department2
Genotoxicity evaluation of self-assembled-micelle inhibitory RNA-targeting amphiregulin (SAMiRNA-AREG), a novel siRNA nanoparticle for the treatment of fibrotic disease2
Early exposure to paracetamol reduces level of testicular testosterone and changes gonadal expression of genes relevant for steroidogenesis in rats offspring2
Toothpastes for children and their detergent contents affect molecular mechanisms of odontogenesis in zebrafish embryos2
Ulva fasciata, a green alga, attenuates the kidney and liver dysfunctions in rats induced by acetaminophen2
Protective effect of dexpanthenol against methotrexate-induced liver oxidative toxicity in rats2
Cytogenetic damage by vanadium(IV) and vanadium(III) on the bone marrow of mice2
The molecular evaluation of thioredoxin (TXN1 & TXN2), thioredoxin reductase 1 (TXNRd1), and oxidative stress markers in a binary rat model of hypo- and hyperthyroidism after treatment with gallic2
Toxicological analysis of synthetic dye orange red on expression of NFκB-mediated inflammatory markers in Wistar rats2
Ferroptosis: action and mechanism of chemical/drug-induced liver injury2
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