Current Problems in Cancer

Article	Citations
Oncolytic virotherapy: Challenges and solutions	50
Nutritional assessment and risk factors associated to malnutrition in patients with esophageal cancer	45
Identification of differentially expressed circulating serum microRNA for the diagnosis and prognosis of Indian non–small cell lung cancer patients	36
Inflammatory myofibroblastic tumor: molecular landscape, targeted therapeutics, and remaining challenges	35
The preoperative systemic inflammation response index (SIRI) independently predicts survival in postmenopausal women with breast cancer	30
Integrated analysis of tumor mutation burden and immune infiltrates in endometrial cancer	25
CAR T-cell therapy for B-cell lymphoma	24
Cancer-related malnutrition management: A survey among Italian Oncology Units and Patients’ Associations	23
Fibrolamellar carcinoma: An entity all its own	21
Chordoma: Current status, problems, and future directions	20
NAT10 upregulation indicates a poor prognosis in acute myeloid leukemia	20
Pediatric brain tumors: the era of molecular diagnostics, targeted and immune-based therapeutics, and a focus on long term neurologic sequelae	17
Exosomal microRNA panels as biomarkers for hematological malignancies	17
The diagnostic and prognostic roles of serum irisin in bladder cancer	16
Depression, anxiety, and their associated factors among Chinese early breast cancer in women under 35 years of age: A cross sectional study	16
Real world experience of treatment and outcome in ALK-rearranged metastatic nonsmall cell lung cancer: A multicenter study from India	15
Monoclonal antibody based radiopharmaceuticals for imaging and therapy	15
Vaginal intraepithelial neoplasia in patients after total hysterectomy	15
Clinical impact of LncRNA XIST and LncRNA NEAT1 for diagnosis of high-risk group breast cancer patients	14
Pembrolizumab induced toxic epidermal necrolysis	14
Prediction of the Pathological Response to Neoadjuvant Chemotherapy in Breast Cancer Patients With MRI-Radiomics: A Systematic Review and Meta-analysis	14
Radiation therapy for patients with locally advanced pancreatic cancer: Evolving techniques and treatment strategies	14
Risk of dementia in prostate cancer survivors: A nationwide cohort study in Korea	14
The association between antibiotic use and survival in renal cell carcinoma patients treated with immunotherapy: a multi-center study	14
Circulating tumor DNA/circulating tumor cells and the applicability in different causes induced hepatocellular carcinoma	14

Conversion therapy for intrahepatic cholangiocarcinoma and tumor downsizing to increase resection rates: A systematic review	13
Folate Receptor as a Biomarker and Therapeutic Target in Solid Tumors	12
Risk of lymph node metastasis and prognostic outcome in early gastric cancer patients with mixed histologic type	12
Advances in the management of alveolar soft part sarcoma	12
Portal vein stent for symptomatic malignant portal vein stenosis: A single-center experience	12
Changes in body composition during neoadjuvant therapy can affect prognosis in rectal cancer patients: An exploratory study	12
The prognostic role of peritoneal cytology in stage IA endometrial endometrioid carcinomas	12
Clinical predictors of response to EGFR-tyrosine kinase inhibitors in EGFR-mutated non-small cell lung cancer: A real-world multicentric cohort analysis from India	12
Metastasectomy and BRAF mutation; an analysis of survival outcome in metastatic colorectal cancer	11
Clinical features and prognostic impact of TCF3–PBX1 in childhood acute lymphoblastic leukemia: A single-center retrospective study of 837 patients from China	11
Prognostic significance of the skeletal muscle index and an inflammation biomarker in patients with breast cancer who underwent postoperative adjuvant radiotherapy	11
Successful management of nongestational ovarian choriocarcinoma complicated with choriocarcinoma syndrome: A case report and a literature review	10
Quality of Life in Adult and Pediatric Patients with Tropomyosin Receptor Kinase Fusion Cancer Receiving Larotrectinib	9
Prolonged persistence of SARS-CoV-2 infection during A+AVD therapy for classical Hodgkin's lymphoma: A case report	9
Comparative efficacy and safety of CDK4/6 and PI3K/AKT/mTOR inhibitors in women with hormone receptor-positive, HER2-negative metastatic breast cancer: a systematic review and network meta-analysis	9
Cancer screenings during the COVID-19 pandemic: An analysis of public interest trends	9
Epidermal growth factor receptor mutation status in pulmonary adenocarcinoma: Multi-institutional data discussion at national conference of “Lung Cancer Management in Indian context”	9
Response to BRAF and MEK1/2 inhibition in a young adult with BRAF V600E mutant epithelioid glioblastoma multiforme: A Case Report and Literature Review	9
Tisotumab vedotin in recurrent or metastatic cervical cancer	8
Disparities in cancer screenings for sexual and gender minorities	8
Gut microbiota differences in Island Hispanic Puerto Ricans and mainland non-Hispanic whites during chemoradiation for rectal cancer: A pilot study	8
The risk of melanoma in patients with chronic lymphocytic leukemia; a population-based study	8
Conventional cardiac risk factors associated with trastuzumab-induced cardiotoxicity in breast cancer: Systematic review and meta-analysis	8
Neoadjuvant chemotherapy followed by surgery in lung cancer: Indian scenario	8
Prognostic value of visceral pleural invasion in the stage pT1-2N2M0 non-small cell lung cancer: A study based on the SEER registry	8
Prognostic significance of tumor multifocality on outcomes in patients with upper tract urothelial carcinoma after radical nephroureterectomy: A cohort study	8
Integration of geriatric assessment into clinical oncology practice: A scoping review	7
Factors associated with mortality from lung cancer in India	7
Comparison of CA 125 alone and risk of ovarian malignancy algorithm (ROMA) in patients with adnexal mass: A multicenter study	7
A targeted approach to phosphoinositide-3-kinase/Akt/mammalian target of rapamycin-induced hyperglycemia	7
Rechallenge with dabrafenib plus trametinib in anaplastic thyroid cancer: A case report and review of literature	7
Using real world data to support regulatory approval of drugs in rare diseases: A review of opportunities, limitations & a case example	7
EGFR mutation testing on plasma and urine samples: A pilot study evaluating the value of liquid biopsy in lung cancer diagnosis and management	7
Non-bacterial cystitis secondary to pembrolizumab: A case report and review of the literature	7
Prognosis for intrahepatic cholangiocarcinoma patients treated with postoperative adjuvant transcatheter hepatic artery chemoembolization	7
The vaginal microbiome: A complex milieu affecting risk of human papillomavirus persistence and cervical cancer	7
Mucocele-like lesions of the breast - A radiological and clinicopathological analysis	6
Uterine artery pulsatility index and serum BMP-9 predict resistance to methotrexate therapy in gestational trophoblastic neoplasia: A cohort study	6
Risk and survival of second primary malignancies following diagnosis of gastric mucosa-associated lymphoid tissue lymphomas: A population-based study	6
Cytotoxic chemotherapy in advanced non–small cell lung cancer with poor performance status: A retrospective analysis from routine clinical practice	6
Novel approaches for treatment of endometrial carcinoma	6
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in the management of peritoneal surface malignancies – An evidence-based review	6
Palbociclib and letrozole in hormone-receptor positive advanced breast cancer: Predictive response and prognostic factors	6
Utility and safety of maintenance chemotherapy in advanced non–small cell lung cancer across various performance status categories: real-world experience	6
Immunotherapy for lung cancer: Focusing on chimeric antigen receptor (CAR)-T cell therapy	6
QT interval prolongation related to afatinib treatment in a patient with metastatic non–small-cell lung cancer	6
Risk of second primary malignancies of adolescent and young adult patients with germ cell cancer: A US population-based analysis	6
Social determinants of health, workforce diversity, and financial toxicity: A review of disparities in cancer care	5
Is lymph node dissection necessary for staging while undergoing nephrectomy in patients with renal cell carcinoma?	5
Changes in the genetic landscape during the malignization of high grade squamous intraepithelial lesion into cervical cancer	5

Severe mental illness in cancer is associated with disparities in psycho-oncological support	5
Hyperprogressive disease in patients receiving immune checkpoint inhibitors	5
High-risk Surgically Resected Renal Cell Carcinoma: Is There a Role for Adjuvant VEGF-TKI Inhibitors?	5
Magnetic resonance imaging criteria of immune checkpoint inhibitor-induced hypophysitis	5
Seasonal influenza vaccination among cancer patients: A systematic review and meta-analysis of the determinants	5
Efficacy of trastuzumab deruxtecan in an advanced gastric cancer patient with brain metastasis	5
The Risk of Second Primary Malignancies in Patients With Lung Neuroendocrine Tumors: A Population-Based Study on SEER Database	5
Late intracranial metastasis from adenoid-cystic carcinoma of the parotid gland: Imaging, histologic and molecular features	5
Delaying adjuvant chemotherapy in advanced gastric cancer patients: Risk factors and its impact on survival outcome	5
Novel prognostic value and potential utility of opioid receptor gene methylation in liquid biopsy for oral cavity cancer	5
Clinical study of serum IGFBP7 in predicting lymphatic metastasis in patients with lung adenocarcinoma	5
Prognostic model in patients with metastatic urothelial carcinoma receiving immune checkpoint inhibitors after platinum failure	5
Triplet chemotherapy vs doublet chemotherapy plus bevacizumab in metastatic, recurrent, and persistent cervical cancer	5
Efficacy of zoledronic acid for prevention of bone loss in early-stage breast cancer patients receiving adjuvant therapy: A meta-analysis of 13 randomized controlled trials	5
Uncommon single and compound EGFR mutations: clinical outcomes of a heterogeneous subgroup of NSCLC	5
Kidney cancer: from genes to therapy	5
Radiation oncologists' perspectives on reducing radiation-induced heart disease in early breast cancer	5
Chemotherapy and immune check point inhibitors in the management of cervical cancer	5
The role of histopathologic testing on apocrine carcinoma of the breast	5
Cancer during a pandemic: A psychosocial telehealth intervention for young adults	4
Characteristics of tumor infiltrating lymphocytes in sinonasal mucosal melanoma and prognosis for patients	4
A case of non–small cell lung cancer with danazol-dependent aplastic anemia induced by pembrolizumab	4
Survival benefit with resection of brain metastases from renal cell carcinoma in the setting of molecular targeted therapy and/or immune therapy	4
VEGF-VEGFR pathway seems to be the best target in hepatic epithelioid hemangioendothelioma: A case series with review of the literature	4
ABCC3 and GSTM5 gene polymorphisms affect overall survival in Polish acute myeloid leukaemia patients	4
Discovery of targeted expression data for novel antibody-based and chimeric antigen receptor-based therapeutics in soft tissue sarcomas using RNA-sequencing: clinical implications	4
Prognostic factors and survival outcomes of women with uterine leiomyosarcoma: A Turkish Uterine Sarcoma Group Study-003	4
High expression of HOXA5 is associated with poor prognosis in acute myeloid leukemia	4
Cancer during Corona Pandemic: Plight of cancer patients when two evils join hands	4
Progress and challenges in gastroesophageal cancer	4
5-Fluorouracil associated neurovascular toxicities	4
Next generation sequencing in lung cancer: An initial experience from India	4
Lung cancer in India: The rewards of REWERDS (REal World Evidence from Retrospective Data analysiS)	4
Untenable dosing: A common pitfall of modern DLT-targeting Phase I designs in oncology	4
Selinexor in patients with advanced and recurrent endometrial cancer	4
Rs2686344 and serum squamous cell carcinoma antigen could predict clinical efficacy of neoadjuvant chemotherapy for cervical cancer	4
Immune checkpoint inhibitors in advanced non–small cell lung cancer: A metacentric experience from India	4
Two-year outcome of concurrent chemoradiation with carboplatin with or without adjuvant carboplatin/fluorouracil in nasopharyngeal cancer: A multicenter randomized trial	4
Pattern of tumor invasion, stromal inflammation, angiogenesis and vascular invasion in oral squamous cell carcinoma – A prognostic study	4
Recurrence of high-grade vaginal intraepithelial neoplasia after various treatments	4
Patient attendance at molecular tumor board: A new means of shared decision making?	4
RING finger protein 187 as a novel potential biomarker for predicting the prognosis of ovarian carcinoma in 2 cancer centers	4
HPV, vaccines, and cervical cancer in a low- and middle-income country	4
AFP-producing Xp11 translocation renal cell carcinoma: Case report and review of the literature	4
Tailoring antiHer2 treatment strategies in breast cancer and beyond	4
Therapeutic options for contralateral axillary lymph node metastasis in breast cancer	3
Strategies to reduce health care disparities for sexual and gender minorities	3
Genome-wide and size-based cell-free DNA indices as predictive biomarkers for locally advanced esophageal squamous cell carcinoma treated with preoperative or definitive chemoradiotherapy	3
Meta-analysis of functional expression and mutational analysis of c-Met in various cancers	3
Patient with EGFR-mutant lung cancer harboring de novo MET amplification successfully treated with gefitinib combined with crizotinib	3
Editorial: Special issue on rare cancers	3
A rare case Of gastric cancer: Isolated vaginal metastasis	3
Emerging immuno-oncology targets in Myelodysplastic Syndromes (MDS)	3
Creation of a quality improvement collaborative to address adolescent and young adult cancer clinical trial enrollment: ATAQI (AYA trial access quality initiative)	3
Urachal carcinoma: A case of a rare neoplasm	3
Altered expression of TGF-β1 and TGF-βR2 in tissue samples compared to blood is associated with food habits and survival in esophageal squamous cell carcinoma	3
Antibody drug conjugates for patients with breast cancer	3
Safety of immune checkpoint inhibitors in patients with preexisting autoimmune disorders	3
18F-sodium fluoride positron emission tomography (NaF-18-PET/CT) radiomic signatures to evaluate responses to alpha-particle Radium-223 dichloride therapy in osteosarcoma metastases	3
Focused review on nutritional status of patients with immunoglobulin light chain amyloidosis	3
Gynecologic and Breast Cancers: What's New in Chemoresistance and Chemosensitivity Tests?	3
Theragnostic significance of tumor-infiltrating lymphocytes and Ki67 in BRAFV600-mutant metastatic melanoma (BRIM-3 trial)	3
Roles and correlation of FOXA1 and ZIC1 in breast cancer	3
Identification of low-density lipoprotein receptor class A domain containing 4 (LDLRAD4) as a prognostic indicator in primary gastrointestinal stromal tumors	3
Successful treatment of paraneoplastic pemphigus and bronchiolitis obliterans associated with follicular lymphoma with obinutuzumab and bendamustine	3
Impact of active tuberculosis on treatment decisions in cancer	3
A real-world, population-based study of the trends for incidence and prognosis in high-grade neuroendocrine tumor of cervix	2
The challenge for nutritional care in a cancer center: The need for integration between clinical nutritionist, oncologist, and palliative care physician	2
Pembrolizumab in advanced renal cell carcinoma: a meta-analysis providing level 1a evidence	2
Mutational profile of hereditary breast and ovarian cancer – Establishing genetic testing guidelines in a developing country	2
Daratumumab Plus Bortezomib and Dexamethasone in Newly Diagnosed Systemic Light Chain Amyloidosis	2
The efficacy evaluation of initial chemotherapy for high-risk gestational trophoblastic neoplasm	2
Does the efficacy of regorafenib differ in chemotherapy refractory metastatic colorectal cancer patients who had mucinous pathology compared to those who had non-mucinous pathology?	2
Cardiovascular risk and undertreatment of dyslipidemia in lung cancer survivors: A nationwide population-based study	2
The impact of preoperative immune checkpoint inhibitors on kidney and bladder cancer surgeries: a systematic review☆	2
The ‘comeback’ of Selinexor: From toxic to tolerable	2
A nomogram to predict survival and guide individualized induction chemotherapy in T3-4N1M0 nasopharyngeal carcinoma	2
Systemic cystic angiomatosis mimicking metastatic cancer	2
Emerging new cell therapies/immune therapies in B-cell non-Hodgkin's lymphoma	2
The impact of performing gastric cancer surgery during holiday periods. A population-based study using Dutch upper gastrointestinal cancer audit (DUCA) data	2

Case report: Delayed retinoblastoma relapse in a lymph node after 9 years of complete remission	2
Clinicopathological and immunohistochemical characteristics of breast cancer patients from Northeast India with special reference to triple negative breast cancer: A prospective study	2
Optimizing anti–body drug conjugates and radiopharmaceuticals for precision therapy: The next frontier in precision oncology	2
Prognostic Factors and Survival According to Tumor Subtype in Women With Breast Cancer Brain Metastases	2
Diversity, equity, and inclusion in genitourinary clinical trials leading to FDA novel drug approval: An assessment of the FDA center for drug evaluation and research drug trials snapshot	2
Imaging of breast cancer–beyond the basics	2
Meaningful engagement of the patient in rare cancer research: sarcoma as an exemplar	2
Thrombotic events in patients using cyclin dependent kinase 4/6 inhibitors, analysis of existing ambulatory risk assessment models and the potential influences of tumor specific risk factors	2
Primary adrenal diffuse large B cell lymphoma arising within an adrenal myelolipoma: A case report and review of the literature	2
Comparative effect of progressive relaxation technique and Benson's technique on anxiety and fatigue in cancer survivors - an experimental study	2
Nodal recurrences after stereotactic body radiotherapy for early stage non–small-cell lung cancer	2
Identification of genetic biomarkers in urine for early detection of prostate cancer	2
Brigatinib-induced tuberculosis reactivation: A case report	1
Nasal hemangiopericytoma presenting with oncogenic osteomalasia: A case report and literature review	1
Conditional survival for high-risk early-stage cervical cancer patients with lymph node metastasis after hysterectomy	1
Harlequin sign in Pancoast tumor	1
Bronchial artery aneurysms arising from antiangiogenic therapy	1
Clinical oncology research; Review on contemporary methodology standards	1
Neutrophil-to-lymphocyte ratio in primary mediastinal germ cell tumors: A retrospective analysis of >20 years single institution experience	1
Examining the Cultural Appropriateness of Advance Care Planning Tools for Adolescents and Young Adults With Cancer: An Example of Cross-Cultural Adaptation of the Voicing My CHOiCES Tool	1
Erythroderma as a paraneoplastic manifestation of small cell lung cancer	1
Contamination of lenalidomide on blister packages after administration and its exposure countermeasures	1
Update on the Role of Imaging in Staging of Common Pediatric Abdominal Tumors	1
Disparities in access to translational research	1
Efficacy evaluation of nilotinib treatment in different genomic subtypes of gastrointestinal stromal tumors: A meta-analysis and systematic review	1
Refractory Hyperammonemic encephalopathy in Fibrolamellar hepatocellular carcinoma, a case report and literature review	1
Cellular Therapy Advances in Chronic Lymphocytic Leukemia and Richter's Syndrome	1
Dural plasmacytoma as the initial presentation of multiple myeloma: A case report and review of the literature	1
Comparison of mutational profiles between triple-negative and hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancers in T2N0-1M0 stage: Implications of TP53 and PIK	1
Multicenter, phase II study of response-adapted lenalidomide-based therapy for transplant-ineligible patients with newly diagnosed multiple myeloma without high-risk features	1
Pituitary enlargement following ipilimumab without long term endocrine dysfunction	1
Imaging Cancer in Neuroradiology	1
Rare case of intramedullary spinal cord metastasis from nasopharyngeal carcinoma	1
Combination of immunotherapy, radiotherapy and denosumab as the best approach even for NSCLC poor prognosis patients: a case report with strong response, prolonged survival and a review of literature	1
The CC ligand chemokine family members CCL17/CCL22 predict the survival and response to immune checkpoint blockade therapy of patients with head and neck squamous cell carcinoma	1
Advances in high-risk localized prostate cancer: Staging and management	1
Extraovarian dysgerminoma in a pregnant woman: an extremely rare finding	1
Long-term outcomes in patients with central and ultracentral non-small cell lung cancer treated with stereotactic body radiotherapy: single-institution experience	1
Survival analysis of transplant-eligible newly-diagnosed multiple myeloma patients harboring t(4;14), t(14;16), and/or del(17p) in the real-world setting	1
The development of numerous radiation-induced cavernous malformations in a germ cell tumor patient: A case report	1
Evaluation and external validation of minor lymphatic pelvic pathway for distant metastases in cervical cancer patients treated with concurrent chemoradiotherapy	1
Beyond EGFR inhibitors in advanced colorectal cancer: Targeting BRAF and HER2	1
A comparative study of cyclophosphamide, thalidomide and dexamethasone (CTD) versus bortezomib and dexamethasone (BDex) in light-chain amyloidosis	1
The role of changes in systemic inflammatory response markers during neoadjuvant chemotherapy in predicting suboptimal surgery in ovarian cancer	1
PEG site metastasis in oropharyngeal squamous cell carcinoma managed with cetuximab and radiotherapy: A case report	1
Perforation of gastric metastasis during chemotherapy with ramucirumab	1
Adjuvant ovarian function suppression and tamoxifen in premenopausal breast cancer patients: A meta-analysis	1