OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical Science is 37. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Emerging role of carbonic anhydrase inhibitors	109
Placental function in maternal obesity	103
The complex role of adipokines in obesity, inflammation, and autoimmunity	92
The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease	91
miR-210 transferred by lung cancer cell-derived exosomes may act as proangiogenic factor in cancer-associated fibroblasts by modulating JAK2/STAT3 pathway	88
The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer	85
Covid-19: the renin–angiotensin system imbalance hypothesis	78
Decoy ACE2-expressing extracellular vesicles that competitively bind SARS-CoV-2 as a possible COVID-19 therapy	73
Bidirectional interaction of airway epithelial remodeling and inflammation in asthma	73
Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseases	72
Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission	67
ACE2 and gut amino acid transport	65
Molecular mechanisms of metabolic associated fatty liver disease (MAFLD): functional analysis of lipid metabolism pathways	59
The molecular mechanism of mechanotransduction in vascular homeostasis and disease	59
Emerging roles for the IL-6 family of cytokines in pancreatic cancer	59
Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway	58
Microvascular disease in chronic kidney disease: the base of the iceberg in cardiovascular comorbidity	58
Pathogenesis of pneumonia and acute lung injury	56
Gut dysbiosis is associated with primary hypothyroidism with interaction on gut-thyroid axis	52
Sepsis plasma-derived exosomal miR-1-3p induces endothelial cell dysfunction by targeting SERP1	51
Negative regulators of TGF-β1 signaling in renal fibrosis; pathological mechanisms and novel therapeutic opportunities	51
ACE2 the Janus-faced protein – from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19	49
Cardiotoxic effects of angiogenesis inhibitors	45
ACE2 and ACE: structure-based insights into mechanism, regulation and receptor recognition by SARS-CoV	45
Targeting perivascular and epicardial adipose tissue inflammation: therapeutic opportunities for cardiovascular disease	44

Cholesterol metabolism: a new molecular switch to control inflammation	43
Therapeutic targeting of TGF-β in cancer: hacking a master switch of immune suppression	42
Experimental data using candesartan and captopril indicate no double-edged sword effect in COVID-19	41
Mechanisms of podocyte injury and implications for diabetic nephropathy	41
Sulforaphane prevents type 2 diabetes-induced nephropathy via AMPK-mediated activation of lipid metabolic pathways and Nrf2 antioxidative function	41
Buformin alleviates sepsis-induced acute lung injury via inhibiting NLRP3-mediated pyroptosis through an AMPK-dependent pathway	40
Transplantation of platelet-derived mitochondria alleviates cognitive impairment and mitochondrial dysfunction in db/db mice	40
Flavonoids in adipose tissue inflammation and atherosclerosis: one arrow, two targets	39
Inflammation: a putative link between phosphate metabolism and cardiovascular disease	39
The immune niche of the liver	39
Myeloid-derived suppressor cells shift Th17/Treg ratio and promote systemic lupus erythematosus progression through arginase-1/miR-322-5p/TGF-β pathway	38
The GCN5: its biological functions and therapeutic potentials	37
ACE2, angiotensin 1-7 and skeletal muscle: review in the era of COVID-19	37
Angiotensin II up-regulates sodium-glucose co-transporter 2 expression and SGLT2 inhibitor attenuates Ang II-induced hypertensive renal injury in mice	37