OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical Science is 32. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Increased angiotensin II formation in the brain modulates cardiovascular homeostasis and erythropoiesis	198
Paradoxical effects of osteoprotegerin on vascular function: inhibiting inflammation while promoting oxidative stress?	176
α-Adrenergic blockade prevented environmental temperature reduction-induced transient portal pressure surge in cirrhotic and portal hypertensive rats	172
Expression of Concern: Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression	168
Maintaining energy provision in the heart: the creatine kinase system in ischaemia–reperfusion injury and chronic heart failure	149
Metal regulation of Mycobacterium tuberculosis SufB intein splicing at the host–pathogen crossroad	140
Measuring muscle protein synthesis in humans and the influence of nutritional state	109
Novel preventive effect of isorhamnetin on electrical and structural remodeling in atrial fibrillation	105
Severe psychiatric disorders and general medical comorbidities: inflammation-related mechanisms and therapeutic opportunities	74
Diminished Rbfox1 increases vascular constriction by dynamically regulating alternative splicing of CaV1.2 calcium channel in hypertension	69
The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models	64
Effect of metformin in a novel experimental model of peripheral artery disease	53
Higher circulating ACE2 and DPP3 but reduced ACE and angiotensinogen in hyperreninemic sepsis patients	52
Cardiovascular research at the Heart of Clinical Science	47
Transcriptome-based exploration of potential molecular targets and mechanisms of selenomethionine in alleviating renal ischemia–reperfusion injury	46
Maternal high-fat diet regulates offspring hepatic ABCG5 expression and cholesterol metabolism via the gut microbiota and its derived butyrate	46
Osteoprotegerin regulates vascular function through syndecan-1 and NADPH oxidase-derived reactive oxygen species	44
Targeting TLR4/3 using chlorogenic acid ameliorates LPS+POLY I:C-induced acute respiratory distress syndrome via alleviating oxidative stress-mediated NLRP3/NF-κB axis	43
Tetramethylpyrazine attenuates renal tubular epithelial cell ferroptosis in contrast-induced nephropathy by inhibiting transferrin receptor and intracellular reactive oxygen species	42
Correction: Enhanced expression of pro-inflammatory mediators and liver X-receptor-regulated lipogenic genes in non-alcoholic fatty liver disease and hepatitis C	40
Targeting protein phosphatase PP2A for cancer therapy: development of allosteric pharmaceutical agents	38
Oxytocin: much more than childbirth and milk letdown	38
Antiviral activities of hemp cannabinoids	38
Endothelin receptor antagonism improves glucose handling, dyslipidemia, and adipose tissue inflammation in obese mice	38
Renal hypertrophy and hyperfiltration is enhanced in early acquired compared with a congenital solitary function kidney model in sheep	38

Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease	36
CEACAM5 inhibits the lymphatic metastasis of head and neck squamous cell carcinoma by regulating epithelial–mesenchymal transition via inhibiting MDM2	36
Hypertension induces gonadal macrophage imbalance, inflammation, lymphangiogenesis, and dysfunction	36
Vascular contributions to cognitive impairment and dementia: the emerging role of 20-HETE	35
Correction: Silencing GOLGA8B inhibits cell invasion and metastasis by suppressing STAT3 signaling pathway in lung squamous cell carcinoma	34
Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice	34
Sex, sepsis and the brain: defining the role of sexual dimorphism on neurocognitive outcomes after infection	33
New insights into the pathophysiology and therapeutic targets of asthma and comorbid chronic rhinosinusitis with or without nasal polyposis	32
The membrane-associated protein 17 (MAP17) is up-regulated in response to empagliflozin on top of RAS blockade in experimental diabetic nephropathy	32