OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical Science is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
α-Adrenergic blockade prevented environmental temperature reduction-induced transient portal pressure surge in cirrhotic and portal hypertensive rats	279
Expression of Concern: Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression	214
Novel preventive effect of isorhamnetin on electrical and structural remodeling in atrial fibrillation	210
Paradoxical effects of osteoprotegerin on vascular function: inhibiting inflammation while promoting oxidative stress?	195
Diminished Rbfox1 increases vascular constriction by dynamically regulating alternative splicing of CaV1.2 calcium channel in hypertension	159
Maintaining energy provision in the heart: the creatine kinase system in ischaemia–reperfusion injury and chronic heart failure	133
The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models	109
Severe psychiatric disorders and general medical comorbidities: inflammation-related mechanisms and therapeutic opportunities	80
Metal regulation of Mycobacterium tuberculosis SufB intein splicing at the host–pathogen crossroad	70
Effect of metformin in a novel experimental model of peripheral artery disease	58
Measuring muscle protein synthesis in humans and the influence of nutritional state	55
Cardiovascular research at the Heart of Clinical Science	54
Transcriptome-based exploration of potential molecular targets and mechanisms of selenomethionine in alleviating renal ischemia–reperfusion injury	52
Osteoprotegerin regulates vascular function through syndecan-1 and NADPH oxidase-derived reactive oxygen species	49
CEACAM5 inhibits the lymphatic metastasis of head and neck squamous cell carcinoma by regulating epithelial–mesenchymal transition via inhibiting MDM2	48
Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease	47
Correction: Enhanced expression of pro-inflammatory mediators and liver X-receptor-regulated lipogenic genes in non-alcoholic fatty liver disease and hepatitis C	46
Renal hypertrophy and hyperfiltration is enhanced in early acquired compared with a congenital solitary function kidney model in sheep	45
Antiviral activities of hemp cannabinoids	45
Hypertension induces gonadal macrophage imbalance, inflammation, lymphangiogenesis, and dysfunction	44
Oxytocin: much more than childbirth and milk letdown	44
Tetramethylpyrazine attenuates renal tubular epithelial cell ferroptosis in contrast-induced nephropathy by inhibiting transferrin receptor and intracellular reactive oxygen species	44
Targeting TLR4/3 using chlorogenic acid ameliorates LPS+POLY I:C-induced acute respiratory distress syndrome via alleviating oxidative stress-mediated NLRP3/NF-κB axis	43
Higher circulating ACE2 and DPP3 but reduced ACE and angiotensinogen in hyperreninemic sepsis patients	43
Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice	43

Vascular contributions to cognitive impairment and dementia: the emerging role of 20-HETE	39
Correction: Silencing GOLGA8B inhibits cell invasion and metastasis by suppressing STAT3 signaling pathway in lung squamous cell carcinoma	36
Maternal high-fat diet regulates offspring hepatic ABCG5 expression and cholesterol metabolism via the gut microbiota and its derived butyrate	36
The membrane-associated protein 17 (MAP17) is up-regulated in response to empagliflozin on top of RAS blockade in experimental diabetic nephropathy	34
NPFFR2-deficient mice fed a high-fat diet develop strong intolerance to glucose	34
Sex, sepsis and the brain: defining the role of sexual dimorphism on neurocognitive outcomes after infection	33