OOIR: Observatory of International Research

Papers

(The median citation count of Neuropeptides is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Intravenous administration of xenin-25 accelerates cyclic ruminal contractions in healthy conscious sheep	46
Medicine and food with particular reference to chinpi, dried citrus peel, and a component of Ninjin'yoeito	31
Enteroendocrine cell-derived peptide YY signalling is stimulated by pinolenic acid or Intralipid and involves coactivation of fatty acid receptors FFA1, FFA4 and GPR119	28
Editorial Board	27
Restraint stress potentiates sensitivity to the antinociceptive effect of morphine through orexin receptors in the ventral tegmental area	24
Amylin regulates testosterone levels via steroidogenesis-related enzymes in the central nervous system of male mice	22
Modulation of temporoammonic-CA1 synapses by neuropeptide Y is through Y1 receptors in mice	22
Changes in ghrelin, substance P and vasoactive intestinal peptide levels in the gastroduodenal mucosa of patients with morbid obesity	21
Benincasa hispida alleviates amyloid pathology by inhibition of Keap1/Nrf2-axis: Emphasis on oxidative and inflammatory stress involved in Alzheimer's disease model	19
Neuropeptide Y modifies a part of diencephalic catecholamine but not indolamine metabolism in chicks depending on feeding status	18
Neuropeptide Y and receptors are associated with the pyroptosis of nucleus pulposus in aging and degenerative intervertebral discs of rats	18
The use of intranasal oxytocin in the treatment of eating disorders	18
Editorial Board	18
Netrin-3 enhances recovery and reduces inflammation following spinal cord injury via suppressing NLRP1 inflammasome activation	16
Transcranial pulsed current stimulation alleviates neuronal pyroptosis and neurological dysfunction following traumatic brain injury via the orexin-A/NLRP3 pathway	15
Neuropeptide FF prevented histamine- or chloroquine-induced acute itch behavior through non-NPFF receptors mechanism in male mice	15
4-hydroxyisoleucine mediated IGF-1/GLP-1 signalling activation prevents propionic acid-induced autism-like behavioural phenotypes and neurochemical defects in experimental rats	14
Chemogenetic activation of arcuate nucleus NPY and NPY/AgRP neurons increases feeding behaviour in mice	14
Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models	14
The effects of corticotropin-releasing factor (CRF) and urocortins on the serotonin (hydroxytryptamine, 5HT) released from the raphe nuclei (RN)	14
Ghrelin protects against rotenone-induced cytotoxicity: Involvement of mitophagy and the AMPK/SIRT1/PGC1α pathway	13
Fat mass and obesity-associated protein regulates RNA methylation associated with spatial cognitive dysfunction after chronic cerebral hypoperfusion	12
A role of noradrenergic receptors in anxiolytic-like effect of high CRF in the rat frontal cortex	11
Editorial Board	11
Physiologically relevant lactate accumulation from exercise or peripheral injection does not alter central or peripheral appetite signaling in mice	11

Editorial Board	11
Role of endothelin in the pathophysiology of migraine: A new view on an old player	11
Long-term administration of ninjin'yoeito to treat frailty in older adults: A case series	10
Investigating the potential of GalR2 as a drug target for neuropathic pain	10
Efficacy of Ninjin'yoeito in treating severe coronavirus disease 2019 in patients in an intensive care unit	10
The role of NPY signaling pathway in diagnosis, prognosis and treatment of stroke	10
Effect of CSF1R inhibitor on glial cells population and remyelination in the cuprizone model	10
Antioxidant PRDX3 gene therapy protects brain cells and prevents neurodegeneration in an animal model of Parkinson's disease	10
Perioperative changes of serum orphanin in diabetic patients and its relationship with sympathetic nervous system	10
Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus	9
Effects of voluntary, and forced exercises on neurotrophic factors and cognitive function in animal models of Parkinson's disease	9
Roles of central orexinergic system on cardiovascular function and acupuncture on intervention of cardiovascular risk: Orexinergic system mediate the role of acupuncture?	8
The phenotypic changes of Schwann cells promote the functional repair of nerve injury	8
Neuropeptide regulation by herbal medicine	8
FGF-18 alleviates memory impairments and neuropathological changes in a rat model of Alzheimer's disease	8
Analgecine protects against cerebral ischemia-reperfusion through apoptosis inhibition and anti-neuroinflammation in rats	8
Immunohistochemical determination of the excitatory and inhibitory axonal endings contacting NUCB2/nesfatin-1 neurons	7
Deciphering the molecular mechanism and crosstalk between Parkinson's disease and breast cancer through multi-omics and drug repurposing approach	7
Metabolic functions of flavonoids: From human epidemiology to molecular mechanism	7
Sex-dimorphic hindbrain lactate regulation of ventromedial hypothalamic nucleus glucoregulatory neuron 5’-AMP-activated protein kinase activity and transmitter marker protein expression	7
The restraint stress-induced antinociceptive effects decreased by antagonism of both orexin receptors within the CA1 region of the hippocampus	7
Interferon beta attenuates recognition memory impairment and improves brain glucose uptake in a rat model of Alzheimer's disease: Involvement of mitochondrial biogenesis and PI3K pathway	7
Disuse muscle atrophy-improving effect of ninjin'yoeito in a mouse model	7
Bromelain decreases oxidative stress and Neuroinflammation and improves motor function in adult male rats with cerebellar Ataxia induced by 3-acetylpyridine	6
CDNF overexpression prevents motor-cognitive dysfunction by intrastriatal CPP-based delivery system in a Parkinson's disease animal model	6
Editorial Board	6
Mechanistic role of proteins and peptides in Management of Neurodegenerative Disorders	6
Thyrotropin-releasing hormone induces Ca2+ increase in a subset of vagal nodose ganglion neurons	6
Editorial Board	6
Localization of neuropeptide receptor NPY4R in rat retina	6
Research progress on the protection and mechanism of active peptides in Alzheimer's disease and Parkinson's disease	6
Cross talk about the role of Neuropeptide Y in CNS disorders and diseases	6
The stress-induced antinociceptive responses to the persistent inflammatory pain involve the orexin receptors in the nucleus accumbens	6
WITHDRAWN: CircBUB1 activates the PI3K/AKT signaling pathway to promote the migration and invasion of glioblastoma cells	6
Editorial Board	6
Cocaine and amphetamine regulated transcript peptide (CART) in the tadpole brain: Response to different energy states	6
Neuropeptide Y Y2 receptors in acute and chronic pain and itch	5
Editorial Board	5
GnRH protective effects against long-term potentiation impairment induced by AANAT-siRNA	5
Alpha-melanocyte stimulating hormone immunoreactivity in the brain of the cichlid fish Oreochromis mossambicus	5
Neurotensin modulation of lipopolysaccharide induced inflammation of gut-liver axis: Evaluation using neurotensin receptor agonist and antagonist	5
Editorial Board	5
The protective effects of orexin B in neuropathic pain by suppressing inflammatory response	5
Trefoil factor 1 (TFF1) reduces cerebral edema and gastric mucosal injury by regulating the EGFR/Src/FAK pathway in an intracerebral hemorrhage rat model	5
Antagonism of the orexin receptors in the ventral tegmental area diminished the stress-induced analgesia in persistent inflammatory pain	5
The suppressive effect of REVERBs on ghrelin and GOAT transcription in gastric ghrelin-producing cells	5
Role of copeptin in the diagnosis of traumatic neuroendocrine dysfunction	5
A Na+ channel receptor of FMRFamide in the cephalopod Sepiella japonica: Identification, characterisation, and expression profiling during different stages of gonadal development	5
Neuropeptides or their receptors in pathogenesis of lung diseases and therapeutic potentials	5
Chemokine CXCL10 regulates pain behaviors via PI3K-AKT signaling pathway in mice	5

Dynorphin A (1–8) inhibits oxidative stress and apoptosis in MCAO rats, affording neuroprotection through NMDA receptor and κ-opioid receptor channels	5
Acute sleep deprivation (ASD) and cardioprotection: Impact of ASD on oxytocin-mediated sympathetic nervous activation preceding myocardial infarction	5
The role of cholecystokinin and peptide YY in feed intake in Atlantic halibut (Hippoglossus hippoglossus) larvae	5
Bee venom as a promising therapeutic strategy in central nervous system diseases	4
Editorial Board	4
Organization of the galaninergic neuronal system in the brain of the gecko Hemidactylus frenatus	4
Neural correlates and potential targets for the contribution of orexin to addiction in cortical and subcortical areas	4
Octovespin, a peptide bioinspired by wasp venom, prevents cognitive deficits induced by amyloid-β in Alzheimer's disease mouse model	4
Measurement of neuropeptide Y with molecularly imprinted polypyrrole on carbon fiber microelectrodes	4
An inclusive study of recent advancements in Alzheimer's disease: A comprehensive review	4
Expression and localization of the neuropeptide Y-Y4 receptor in the chick spleen: mRNA upregulation by high ambient temperature	4
Neuroprotective effect of the PACAP-ADNP axis on SOD1G93A mutant motor neuron death induced by trophic factors deprivation	4
Phoenixin-14 inhibits the formation of cerebral aneurysms in rats by downregulating the p38/NF-κB signaling pathway	4
Editorial Board	4
Kinetics of neuropeptide Y, catecholamines, and physiological responses during moderate and heavy intensity exercises	4
Search for lipidized PrRP analogs with strong anorexigenic effect: In vitro and in vivo studies	4
How neuroactive factors mediates immune responses during pregnancy: An interdisciplinary view	4
Research on the function of the Cend1 regulatory mechanism on p75NTR signaling in spinal cord injury	4
Developmental regulation and lateralization of N-methyl-d-aspartate (NMDA) receptors in the rat hippocampus	4
The impact of endogenous N/OFQ on DPN: Insights into lower limb blood flow regulation in rats	4
Illuminating the neuropeptide Y4 receptor and its ligand pancreatic polypeptide from a structural, functional, and therapeutic perspective	4
MP-13, a novel chimeric peptide of morphiceptin and pepcan-9, produces potent antinociception with limited side effects	3
Changes in working memory induced by lipopolysaccharide administration in mice are associated with metabotropic glutamate receptors 5 and contrast with changes induced by cyclooxygenase-2: Involvement	3
Editorial Board	3
Expression of phoenixin-14 and nesfatin-1 in the hypothalamo–pituitary–gonadal axis in the phases of the estrous cycle	3
Interactions between the regulatory peptide 26RFa (QRFP) and insulin in the regulation of glucose homeostasis in two complementary models: The high fat 26RFa-deficient mice and the streptozotocin insu	3
Metformin promotes Schwann cell remyelination, preserves neural tissue and improves functional recovery after spinal cord injury	3
Sucralose uses reward pathways to promote acute caloric intake	3
Expression of immune-related proteins and their association with neuropeptides in adolescent patients with anorexia nervosa	3
Opioid growth factor receptor: Anatomical distribution and receptor colocalization in neurons of the adult mouse brain	3
Effects of substance P on human cerebral microvascular endothelial cell line hCMEC/D3 are mediated exclusively through a truncated NK-1 receptor and depend on cell confluence	3
Neurotransmitters and Neuropeptides decrease PD-1 in T cells of healthy subjects and patients with hepatocellular carcinoma (HCC), and increase their proliferation and eradication of HCC cells	3
GSK-3β as a target for apigenin-induced neuroprotection against Aβ 25–35 in a rat model of Alzheimer's disease	3
WITHDRAWN: Age-dependent modulation of RFRP-3 neurons in female mice	3
The regulatory effects of the apelin/APJ system on depression: A prospective therapeutic target	3
Neuroanatomical mapping of spexin and nesfatin-1-expressing neurons in the human brainstem	3
Pharmacological profile of agmatine: An in-depth overview	3
Potentiation of microglial endocannabinoid signaling alleviates neuroinflammation in Alzheimer's disease	3
Bee venom ameliorates oxidative stress and histopathological changes of hippocampus, liver and testis during status epileptics	3
Tetrahydroxy stilbene glycoside regulates TGF-β/fractalkine/CX3CR1 based on network pharmacology in APP/PS1 mouse model	3
Several neuropeptides involved in parkinsonian neuroprotection modulate the firing properties of nigral dopaminergic neurons	2
Editorial Board	2
The role of sensory and sympathetic nerves in craniofacial bone regeneration	2
ACTH(6-9)-Pro-Gly-Pro ameliorates anxiety-like and depressive-like behaviour and gut mucosal microbiota composition in rats under conditions of chronic restraint stress	2
Intrathecal administration of botulinum toxin type a antagonizes neuropathic pain by countering increased vesicular nucleotide transporter expression in the spinal cord of chronic constriction injury	2
Melittin protects against neural cell damage in rats following ischemic stroke	2
Ninjin'yoeito, a herbal medicine, enhances glucose tolerance in mice	2
Protective effect of N-acetyl cysteine on the mitochondrial dynamic imbalance in temporal lobe epilepsy: Possible role of mTOR	2
Effects of an herbal adaptogen feed-additive on feeding-related hypothalamic neuropeptides in chronic cyclic heat-stressed chickens	2
Editorial Board	2
Neuromedin U modulates neuronal excitability in rat hippocampal slices	2
Multiple stage IV colorectal cancers in a patient who received multidisciplinary treatment, including chemotherapy and Japanese Kampo medicine: A case report	2
Ac-SDKP peptide improves functional recovery following spinal cord injury in a preclinical model	2
Pyroglutamylated RFamide peptide (QRFP): Role in early testicular development in relation to Sertoli cell maturation in prepubertal mice	2
Editorial Board	2
Curcumin attenuates morphine dependence by modulating μ-opioid receptors and glial cell-activated neuroinflammation in rat	2
Effect of valproic acid combined with transplantation of olfactory ensheathing cells modified by neurotrophic 3 gene on nerve protection and repair after traumatic brain injury	2
Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food	2
Ninjin'yoeito modulates feeding and activity under negative energy balance conditions via the NPY system	2