OOIR: Observatory of International Research

Papers

(The median citation count of Neuropeptides is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Amylin regulates testosterone levels via steroidogenesis-related enzymes in the central nervous system of male mice	38
Editorial Board	31
Enteroendocrine cell-derived peptide YY signalling is stimulated by pinolenic acid or Intralipid and involves coactivation of fatty acid receptors FFA1, FFA4 and GPR119	28
Interaction of glucocorticoids and interleukins in the control of hypothalamic neurohypophysial system output in salt loaded male rats	28
Inhibitory modulation of gastrointestinal motility in mice by Tyr-c[D-Lys-Gly-p-F-Phe-Asp]-D-Pro-NH2, a novel cyclic hexapeptide with multifunctional opioid agonism	27
Modulation of temporoammonic-CA1 synapses by neuropeptide Y is through Y1 receptors in mice	27
Intravenous administration of xenin-25 accelerates cyclic ruminal contractions in healthy conscious sheep	25
Neuropeptide Y and receptors are associated with the pyroptosis of nucleus pulposus in aging and degenerative intervertebral discs of rats	24
Restraint stress potentiates sensitivity to the antinociceptive effect of morphine through orexin receptors in the ventral tegmental area	24
Revisited case for intranasal neuropeptide Y based therapeutics: From preclinical to clinical	24
Editorial Board	23
Neuropeptide FF prevented histamine- or chloroquine-induced acute itch behavior through non-NPFF receptors mechanism in male mice	22
Netrin-3 enhances recovery and reduces inflammation following spinal cord injury via suppressing NLRP1 inflammasome activation	22
The use of intranasal oxytocin in the treatment of eating disorders	18
Salivary oxytocin responses in mothers and full-term newborns in early skin-to-skin contact for the first 2 hours after birth: Effects of synthetic oxytocin administration and epidural analgesia in la	17
Chemogenetic activation of arcuate nucleus NPY and NPY/AgRP neurons increases feeding behaviour in mice	17
Transcranial pulsed current stimulation alleviates neuronal pyroptosis and neurological dysfunction following traumatic brain injury via the orexin-A/NLRP3 pathway	15
4-hydroxyisoleucine mediated IGF-1/GLP-1 signalling activation prevents propionic acid-induced autism-like behavioural phenotypes and neurochemical defects in experimental rats	15
Physiologically relevant lactate accumulation from exercise or peripheral injection does not alter central or peripheral appetite signaling in mice	15
Netrin-3 rectifies diabetes-induced cognitive impairment by counteracting hippocampal oxidative stress and NLRP3 inflammasome activation	15
Editorial Board	14
The effects of corticotropin-releasing factor (CRF) and urocortins on the serotonin (hydroxytryptamine, 5HT) released from the raphe nuclei (RN)	14
Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models	13
Profile of cocaine and amphetamine regulated transcript peptide (CARTp) and Corticotropin-releasing factor (CRF) in the brain of Euphlyctis cyanophlyctis during puddle desiccation	13
Expression of the Galanin system in the human pancreas, pancreatitis, and pancreatic cancer: Association with nodal involvement and perineural invasion	12

Kisspeptin-54 ameliorates chondrocyte senescence in osteoarthritis via SIRT3-mediated telomere protection and p53 acetylation inhibition	12
Fat mass and obesity-associated protein regulates RNA methylation associated with spatial cognitive dysfunction after chronic cerebral hypoperfusion	12
Investigating the potential of GalR2 as a drug target for neuropathic pain	12
Role of endothelin in the pathophysiology of migraine: A new view on an old player	12
Antioxidant PRDX3 gene therapy protects brain cells and prevents neurodegeneration in an animal model of Parkinson's disease	11
Substance P mitigates lipopolysaccharide induced cognitive impairment in rats in a dose dependent manner	10
Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus	10
The role of NPY signaling pathway in diagnosis, prognosis and treatment of stroke	10
Irisin alleviates anxiety and deficits in fear extinction in PTSD within SPS mouse model	10
Effects of voluntary, and forced exercises on neurotrophic factors and cognitive function in animal models of Parkinson's disease	10
FGF-18 alleviates memory impairments and neuropathological changes in a rat model of Alzheimer's disease	10
Perioperative changes of serum orphanin in diabetic patients and its relationship with sympathetic nervous system	10
Systemic irisin treatment modulates cognitive function through VEGF-associated hippocampal vascular signaling in chronic cerebral hypoperfusion	9
PQK7: A novel peptide inhibitor targeting alpha-synuclein fibrillogenesis in Parkinson's disease	9
The influence of galanin receptor agonist during the seasonal recrudescence and nonbreeding phases of the ovarian cycle in the gekkonid lizard Hemidactylus frenatus	9
Deciphering the molecular mechanism and crosstalk between Parkinson's disease and breast cancer through multi-omics and drug repurposing approach	9
The restraint stress-induced antinociceptive effects decreased by antagonism of both orexin receptors within the CA1 region of the hippocampus	9
The phenotypic changes of Schwann cells promote the functional repair of nerve injury	9
Interferon beta attenuates recognition memory impairment and improves brain glucose uptake in a rat model of Alzheimer's disease: Involvement of mitochondrial biogenesis and PI3K pathway	9
Immunohistochemical determination of the excitatory and inhibitory axonal endings contacting NUCB2/nesfatin-1 neurons	9
Effects of intranasal oxytocin on fear, pain and aversive memory	9
Sex-dimorphic hindbrain lactate regulation of ventromedial hypothalamic nucleus glucoregulatory neuron 5’-AMP-activated protein kinase activity and transmitter marker protein expression	8
The stress-induced antinociceptive responses to the persistent inflammatory pain involve the orexin receptors in the nucleus accumbens	8
Molecular mechanisms of GDNF/GFRA1/RET and PI3K/AKT/ERK signaling interplay in neuroprotection: Therapeutic strategies for treating neurological disorders	8
CDNF overexpression prevents motor-cognitive dysfunction by intrastriatal CPP-based delivery system in a Parkinson's disease animal model	8
Dynorphin B induces mitochondrial fragmentation in NSCLC through the PKD/DRP-1 signaling pathway	8
WITHDRAWN: CircBUB1 activates the PI3K/AKT signaling pathway to promote the migration and invasion of glioblastoma cells	8
Bromelain decreases oxidative stress and Neuroinflammation and improves motor function in adult male rats with cerebellar Ataxia induced by 3-acetylpyridine	8
Neuropeptide Y receptor modulation of dopamine transmission in the nucleus accumbens core	8
Thyrotropin-releasing hormone induces Ca2+ increase in a subset of vagal nodose ganglion neurons	8
Therapeutic potential of small peptides in Alzheimer's disease: Advances in memory restoration and targeted delivery systems	8
Re-thinking neuropeptide therapeutics: What Neuropeptide Y and Galanin teach us about stress, resilience, and drug design	8
Mechanistic role of proteins and peptides in Management of Neurodegenerative Disorders	7
Research progress on the protection and mechanism of active peptides in Alzheimer's disease and Parkinson's disease	7
Editorial Board	7
Editorial Board	7
GnRH protective effects against long-term potentiation impairment induced by AANAT-siRNA	7
A Na+ channel receptor of FMRFamide in the cephalopod Sepiella japonica: Identification, characterisation, and expression profiling during different stages of gonadal development	7
Nesfatin1 attenuates autism-like behavior via antioxidant, anti-inflammatory activities in a prenatal valproic acid-induced rat model of autism	7
Neuropeptide Y Y2 receptors in acute and chronic pain and itch	7
Cross talk about the role of Neuropeptide Y in CNS disorders and diseases	7
Differential effects of orexin system activation on dizocilpine-induced schizophrenia-like behaviors in mice	6
Neural correlates and potential targets for the contribution of orexin to addiction in cortical and subcortical areas	6
Antagonism of the orexin receptors in the ventral tegmental area diminished the stress-induced analgesia in persistent inflammatory pain	6
The protective effects of orexin B in neuropathic pain by suppressing inflammatory response	6
An inclusive study of recent advancements in Alzheimer's disease: A comprehensive review	6
Acute sleep deprivation (ASD) and cardioprotection: Impact of ASD on oxytocin-mediated sympathetic nervous activation preceding myocardial infarction	6
Editorial Board	6
Research on the function of the Cend1 regulatory mechanism on p75NTR signaling in spinal cord injury	6
Editorial Board	6

Trefoil factor 1 (TFF1) reduces cerebral edema and gastric mucosal injury by regulating the EGFR/Src/FAK pathway in an intracerebral hemorrhage rat model	6
Neuroprotective effect of the PACAP-ADNP axis on SOD1G93A mutant motor neuron death induced by trophic factors deprivation	6
Neurotensin modulation of lipopolysaccharide induced inflammation of gut-liver axis: Evaluation using neurotensin receptor agonist and antagonist	6
Measurement of neuropeptide Y with molecularly imprinted polypyrrole on carbon fiber microelectrodes	6
Neuropeptides or their receptors in pathogenesis of lung diseases and therapeutic potentials	6
Editorial Board	6
Bee venom as a promising therapeutic strategy in central nervous system diseases	6
Search for lipidized PrRP analogs with strong anorexigenic effect: In vitro and in vivo studies	5
The impact of endogenous N/OFQ on DPN: Insights into lower limb blood flow regulation in rats	5
Changes in working memory induced by lipopolysaccharide administration in mice are associated with metabotropic glutamate receptors 5 and contrast with changes induced by cyclooxygenase-2: Involvement	5
ATP drives the leptin inhibition of voltage-gated calcium channels via AMPK in isolated neurons of arcuate nucleus in male rats	5
Expression and localization of the neuropeptide Y-Y4 receptor in the chick spleen: mRNA upregulation by high ambient temperature	5
Organization of the galaninergic neuronal system in the brain of the gecko Hemidactylus frenatus	5
Phoenixin-14 inhibits the formation of cerebral aneurysms in rats by downregulating the p38/NF-κB signaling pathway	5
Evaluating the efficacy of neurotensin receptor-1 antagonist SR48692 in high-fat diet-induced neurotoxicity in mice: An in vivo study	4
Editorial Board	4
Bee venom ameliorates oxidative stress and histopathological changes of hippocampus, liver and testis during status epileptics	4
Metformin promotes Schwann cell remyelination, preserves neural tissue and improves functional recovery after spinal cord injury	4
Expression of phoenixin-14 and nesfatin-1 in the hypothalamo–pituitary–gonadal axis in the phases of the estrous cycle	4
Opioid growth factor receptor: Anatomical distribution and receptor colocalization in neurons of the adult mouse brain	4
Effects of substance P on human cerebral microvascular endothelial cell line hCMEC/D3 are mediated exclusively through a truncated NK-1 receptor and depend on cell confluence	4
Effects of an herbal adaptogen feed-additive on feeding-related hypothalamic neuropeptides in chronic cyclic heat-stressed chickens	4
Protective effect of N-acetyl cysteine on the mitochondrial dynamic imbalance in temporal lobe epilepsy: Possible role of mTOR	4
Editorial Board	4
Melittin protects against neural cell damage in rats following ischemic stroke	4
Interactions between the regulatory peptide 26RFa (QRFP) and insulin in the regulation of glucose homeostasis in two complementary models: The high fat 26RFa-deficient mice and the streptozotocin insu	4
Pharmacological profile of agmatine: An in-depth overview	4
Illuminating the neuropeptide Y4 receptor and its ligand pancreatic polypeptide from a structural, functional, and therapeutic perspective	4
Neuroanatomical mapping of spexin and nesfatin-1-expressing neurons in the human brainstem	4
Several neuropeptides involved in parkinsonian neuroprotection modulate the firing properties of nigral dopaminergic neurons	4
Interplay of neuropeptide Y and autophagy in Alzheimer's disease: Therapeutic perspectives and mechanistic insights	4
The role of sensory and sympathetic nerves in craniofacial bone regeneration	4
MP-13, a novel chimeric peptide of morphiceptin and pepcan-9, produces potent antinociception with limited side effects	4
The regulatory effects of the apelin/APJ system on depression: A prospective therapeutic target	4
Sucralose uses reward pathways to promote acute caloric intake	4
Neuropeptide systems in temporal lobe epilepsy	4
Microglial activation in diabetic neuropathic pain: Molecular trigger mechanisms, neuroimmune crosstalk, and emerging therapeutic targets	4
Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food	3
In silico identification and deorphanisation of an allatostatin C GPCR system in the cephalopod Octopus vulgaris reveal two receptors with distinct potency	3
The role of salivary neurotensin and oxytocin in emotional responses to stress inoculation	3
Intrathecal administration of botulinum toxin type a antagonizes neuropathic pain by countering increased vesicular nucleotide transporter expression in the spinal cord of chronic constriction injury	3
Effects of somatostatin, a somatostatin agonist, and an antagonist, on a putative migraine trigger pathway	3
Curcumin attenuates morphine dependence by modulating μ-opioid receptors and glial cell-activated neuroinflammation in rat	3
Editorial Board	3
Editorial Board	3
A comparative study on the effects of human serum albumin and α-melanocyte-stimulating hormone fusion proteins on the anti-neuroinflammatory in the central nervous system of adult mice	3
Modulation of neuropathological pathways by bioactive peptides and proteins/polypeptides: Targeting oxidative stress in neurodegenerative diseases	3
Bromelain administration improves learning and memory, reduces astrogliosis, and increases BDNF expression in rats with thioacetamide-induced hepatic encephalopathy model	3
Effect of valproic acid combined with transplantation of olfactory ensheathing cells modified by neurotrophic 3 gene on nerve protection and repair after traumatic brain injury	3
The contribution of hypothalamic neuropeptide Y to age-dependent body weight changes	3
Anandamide improves food intake and orexinergic neuronal activity in the chronic sleep deprivation induction model in rats by modulating the expression of the CB1 receptor in the lateral hypothalamus	3