OOIR: Observatory of International Research

Papers

(The median citation count of Neuropeptides is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Spermidine, an autophagy inducer, as a therapeutic strategy in neurological disorders	34
The role of oxytocin and vasopressin dysfunction in cognitive impairment and mental disorders	33
Role of neurotrophins in pregnancy and offspring brain development	33
Dysfunctional Nurr1 promotes high glucose-induced Müller cell activation by up-regulating the NF-κB/NLRP3 inflammasome axis	30
Chronic high-fat diet consumption induces an alteration in plasma/brain neurotensin signaling, metabolic disturbance, systemic inflammation/oxidative stress, brain apoptosis, and dendritic spine loss	30
GSK-3β as a target for apigenin-induced neuroprotection against Aβ 25–35 in a rat model of Alzheimer's disease	24
Activation of NPY receptor subtype 1 by [D-His26]NPY is sufficient to prevent development of anxiety and depressive like effects in the single prolonged stress rodent model of PTSD	21
Metabolic functions of flavonoids: From human epidemiology to molecular mechanism	20
Neuroprotective gain of Apelin/APJ system	20
The orexinergic neural pathway from the lateral hypothalamus to the nucleus accumbens and its regulation of palatable food intake	18
Neuropeptide galanin and its effects on metabolic and reproductive disturbances in female rats with estradiol valerate (EV) - Induced polycystic ovary syndrome (PCOS)	18
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats	17
Genetic deletion of the angiotensin-(1–7) receptor Mas leads to alterations in gut villi length modulating TLR4/PI3K/AKT and produces microbiome dysbiosis	17
Involvement of orexin-A in the regulation of neuronal activity and emotional behaviors in central amygdala in rats	15
Neuroprotective effects of glucagon-like peptide-1 (GLP-1) analogues in epilepsy and associated comorbidities	15
Ninjinyoeito improves anxiety behavior in neuropeptide Y deficient zebrafish	15
Ghrelin protects against rotenone-induced cytotoxicity: Involvement of mitophagy and the AMPK/SIRT1/PGC1α pathway	15
Benincasa hispida alleviates amyloid pathology by inhibition of Keap1/Nrf2-axis: Emphasis on oxidative and inflammatory stress involved in Alzheimer's disease model	15
Neuropeptides as regulators of the hypothalamus-pituitary-gonadal (HPG) axis activity and their putative roles in stress-induced fertility disorders	14
The distribution of Neuropeptide FF and Neuropeptide VF in central and peripheral tissues and their role in energy homeostasis control	13
Ang (1–7)/Mas receptor-axis activation promotes amyloid beta-induced altered mitochondrial bioenergetics in discrete brain regions of Alzheimer's disease-like rats	13
Regulatory effects of ghrelin on endoplasmic reticulum stress, oxidative stress, and autophagy: Therapeutic potential	13
Effects of trigeminal nerve injury on the expression of galanin and its receptors in the rat trigeminal ganglion	13
Neurotrophin-3 and neurotrophin-4: The unsung heroes that lies behind the meninges	13
Neuropeptides are associated with pain threshold and bone microstructure in ovariectomized rats	13

Potentiation of microglial endocannabinoid signaling alleviates neuroinflammation in Alzheimer's disease	13
An integrated approach to unravel a putative crosstalk network in Alzheimer’s disease and Parkinson’s disease	12
Cognitive-enhancing effects of fibrauretine on Aβ1–42-induced Alzheimer's disease by compatibilization with ginsenosides	12
Exogenous insulin-like growth factor 1 attenuates acute ischemic stroke-induced spatial memory impairment via modulating inflammatory response and tau phosphorylation	12
Leucine-enkephalin-immunoreactive neurons in the brain of the cichlid fish Oreochromis mossambicus	12
The bee venom active compound melittin protects against bicuculline-induced seizures and hippocampal astrocyte activation in rats	11
Effects of mesenchymal stem cells transplantation on multiple sclerosis patients	11
Role of ocular surface neurobiology in neuronal-mediated inflammation in dry eye disease	11
Changes in ghrelin, substance P and vasoactive intestinal peptide levels in the gastroduodenal mucosa of patients with morbid obesity	11
Long term neuroprotective effects of acute single dose MK-801treatment against traumatic brain injury in immature rats	11
ACTH(6-9)-Pro-Gly-Pro ameliorates anxiety-like and depressive-like behaviour and gut mucosal microbiota composition in rats under conditions of chronic restraint stress	10
Neuropeptide Y tonically inhibits an NMDAR➔AC1➔TRPA1/TRPV1 mechanism of the affective dimension of chronic neuropathic pain	10
Neuropeptide Y is involved in the regulation of quiescence of hematopoietic stem cells	10
Phytogenic feed- and water-additives improve feed efficiency in broilers via modulation of (an)orexigenic hypothalamic neuropeptide expression	10
Apelin-13 attenuates spatial memory impairment by anti-oxidative, anti-apoptosis, and anti-inflammatory mechanism against ethanol neurotoxicity in the neonatal rat hippocampus	10
Effect of CSF1R inhibitor on glial cells population and remyelination in the cuprizone model	9
Combination therapy with neuropeptides for the treatment of anxiety disorder	9
Cocaine- and amphetamine-regulated transcript protects synaptic structures in neurons after ischemic cerebral injury	9
Effect of (m)RVD-hemopressin against Aβ1-42-induced apoptosis and inhibition of neurite outgrowth in SH-SY5Y cells	9
GLP-1 preserves β cell function via improvement on islet insulin signaling in high fat diet feeding mice	9
Erythropoietin shows gender dependent positive effects on social deficits, learning/memory impairments, neuronal loss and neuroinflammation in the lipopolysaccharide induced rat model of autism	9
The effects of neurosteroid allopregnanolone on synaptic dysfunction in the hippocampus in experimental parkinsonism rats: An electrophysiological and molecular study	8
Orexin receptor antagonists in the pathophysiology and treatment of sleep disorders and epilepsy	8
Expression of immune-related proteins and their association with neuropeptides in adolescent patients with anorexia nervosa	8
Anorexigenic effects of substance P in Coturnix japonica	8
Neuromedin U modulates neuronal excitability in rat hippocampal slices	7
Growth hormone treatment for Prader-Willi syndrome: A review	7
Medicine and food with particular reference to chinpi, dried citrus peel, and a component of Ninjin'yoeito	7
Application of Kampo medicines for the palliation of cancer cachexia	7
Differential role of specific cardiovascular neuropeptides in pain regulation: Relevance to cardiovascular diseases	7
Onion component, isoalliin, stimulates feeding and activates the arcuate nucleus neuropeptide Y, ghrelin- and Ninjin'yoeito-responsive neurons	7
Interferon beta attenuates recognition memory impairment and improves brain glucose uptake in a rat model of Alzheimer's disease: Involvement of mitochondrial biogenesis and PI3K pathway	7
Angiotensin-converting enzyme 2 activator, DIZE in the basolateral amygdala attenuates the tachycardic response to acute stress by modulating glutamatergic tone	7
Function study of vasoactive intestinal peptide on chick embryonic bone development	7
Altered neurotransmission in stress-induced depressive disorders: The underlying role of the amygdala in depression	6
Neurotransmitters and Neuropeptides decrease PD-1 in T cells of healthy subjects and patients with hepatocellular carcinoma (HCC), and increase their proliferation and eradication of HCC cells	6
Modulating Aβ Fibrillogenesis with ‘Trojan’ peptides	6
Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY)	6
Hemokinin-1 and substance P stimulate production of inflammatory cytokines and chemokines in human colonic mucosa via both NK1 and NK2 tachykinin receptors	6
The management and metabolic characterization: hyperthyroidism and hypothyroidism	6
Deciphering the molecular mechanism and crosstalk between Parkinson's disease and breast cancer through multi-omics and drug repurposing approach	6
Gyroxin, a toxin from Crotalus durissus terrificus snake venom, induces a calcium dependent increase in glutamate release in mice brain cortical synaptosomes	6
Phoneutria nigriventer Tx3-3 peptide toxin reduces fibromyalgia symptoms in mice	6
Changes in post-oral glucose challenge pancreatic polypeptide hormone levels following metabolic surgery: A comparison of gastric bypass and sleeve gastrectomy	6
Kinetics of neuropeptide Y, catecholamines, and physiological responses during moderate and heavy intensity exercises	6
Effect of intranasal administration of neuropeptide Y and single prolonged stress on food consumption and body weight in male rats	6
Effects of exercise on BDNF-TrkB signaling in the paraventricular nucleus and rostral ventrolateral medulla in rats post myocardial infarction	6
The patterns of exercise-induced β-endorphin expression in the central nervous system of rats	5
Efficacy of Ninjin'yoeito in treating severe coronavirus disease 2019 in patients in an intensive care unit	5
Protective effect of N-acetyl cysteine on the mitochondrial dynamic imbalance in temporal lobe epilepsy: Possible role of mTOR	5

Peripheral apelin mediates visceral hypersensitivity and impaired gut barrier in a rat irritable bowel syndrome model	5
Exercise modulates APOE expression in brain cortex of female APOE3 and APOE4 targeted replacement mice	5
Sexual function and depression in polycystic ovary syndrome: Is it associated with inflammation and neuromodulators?	5
Increased monocyte chemoattractant protein-1 and nitrotyrosine are associated with increased body weight in patients with rheumatoid arthritis after etanercept therapy	5
Dynorphin A (1–8) inhibits oxidative stress and apoptosis in MCAO rats, affording neuroprotection through NMDA receptor and κ-opioid receptor channels	5
Neuropeptide Y enhances proliferation and chondrogenic differentiation of ATDC5 cells	5
Superoxide anions modulate the effects of alarin in the paraventricular nucleus on sympathetic activity and blood pressure in spontaneously hypertensive rats	5
Alteration of orexin-A and PKCα in the postmortem brain of pure-opioid and multi-drug abusers	5
Neural correlates and potential targets for the contribution of orexin to addiction in cortical and subcortical areas	5
The effect of amisulpride, olanzapine, quetiapine, and aripiprazole single administration on c-Fos expression in vasopressinergic and oxytocinergic neurons of the rat hypothalamic paraventricular nucl	5
Central regulatory mechanisms of visceral sensation in response to colonic distension with special reference to brain orexin	5
Evaluating the usefulness of Ninjin'yoeito Kampo medicine in combination with rehabilitation therapy in patients with frailty complicated by intractable dizziness	5
4-hydroxyisoleucine mediated IGF-1/GLP-1 signalling activation prevents propionic acid-induced autism-like behavioural phenotypes and neurochemical defects in experimental rats	5
Adrenomedullin 2 attenuates LPS-induced inflammation in microglia cells by receptor-mediated cAMP-PKA pathway	4
Alpha-melanocyte stimulating hormone immunoreactivity in the brain of the cichlid fish Oreochromis mossambicus	4
Ninjin'yoeito modulates feeding and activity under negative energy balance conditions via the NPY system	4
hucMSCs transplantation promotes locomotor function recovery, reduces apoptosis and inhibits demyelination after SCI in rats	4
Octovespin, a peptide bioinspired by wasp venom, prevents cognitive deficits induced by amyloid-β in Alzheimer's disease mouse model	4
Developmental regulation and lateralization of N-methyl-d-aspartate (NMDA) receptors in the rat hippocampus	4
Age related changes of neuropeptide Y-ergic system in the rat duodenum	4
Neuropeptide Y modifies a part of diencephalic catecholamine but not indolamine metabolism in chicks depending on feeding status	4
Protective effect of a spider recombinant toxin in a murine model of Huntington's disease	4
Disuse muscle atrophy-improving effect of ninjin'yoeito in a mouse model	4
A role of noradrenergic receptors in anxiolytic-like effect of high CRF in the rat frontal cortex	4
The role of cholecystokinin and peptide YY in feed intake in Atlantic halibut (Hippoglossus hippoglossus) larvae	4
Zona incerta projection neurons and GABAergic and GLP-1 mechanisms in the nucleus accumbens are involved in the control of gastric function and food intake	4
Involvement of the gabaergic, serotonergic and glucocorticoid mechanism in the anxiolytic-like effect of mastoparan-L	4
How neuroactive factors mediates immune responses during pregnancy: An interdisciplinary view	3
Multiple stage IV colorectal cancers in a patient who received multidisciplinary treatment, including chemotherapy and Japanese Kampo medicine: A case report	3
NOP01, a NOP receptor agonist, produced potent and peripherally restricted antinociception in a formalin-induced mouse orofacial pain model	3
Long-term administration of ninjin'yoeito to treat frailty in older adults: A case series	3
Chronic oral nicotine administration and withdrawal regulate the expression of neuropeptide Y and its receptors in the mesocorticolimbic system	3
Ninjin'yoeito, a herbal medicine, enhances glucose tolerance in mice	3
Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models	3
A retrospective study on the efficacy of Ninjin’yoeito on fatigue in patients with interstitial pneumonia	3
Opioid growth factor receptor: Anatomical distribution and receptor colocalization in neurons of the adult mouse brain	3
Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food	3
Effects of voluntary, and forced exercises on neurotrophic factors and cognitive function in animal models of Parkinson's disease	3
Inhibition of NR2A reduces calcitonin gene-related peptide gene expression induced by cortical spreading depression in rat amygdala	3
Role of copeptin in the diagnosis of traumatic neuroendocrine dysfunction	3
Survey of problems in Kampo curriculum and the need for interdisciplinary collaboration education in Japanese medical, pharmacy, dental, and nursing departments	3
Lack of NPY in neurotensin neurons leads to a lean phenotype	3
A regulatable adenovector system for GDNF and GFP delivery in the rat hippocampus	3
Impact of caudal hindbrain glycogen metabolism on A2 noradrenergic neuron AMPK activation and ventromedial hypothalamic nucleus norepinephrine activity and glucoregulatory neurotransmitter marker prot	3
Ischemia-induced retinal injury is attenuated by Neurovespina, a peptide from the venom of the social wasp Polybia occidentalis	3
Analgecine protects against cerebral ischemia-reperfusion through apoptosis inhibition and anti-neuroinflammation in rats	3
Neurotensin modulation of lipopolysaccharide induced inflammation of gut-liver axis: Evaluation using neurotensin receptor agonist and antagonist	3
PACAP inhibition alleviates neuropathic pain by modulating Nav1.7 through the MAPK/ERK signaling pathway in a rat model of chronic constriction injury	3
Antagonism of the orexin receptors in the ventral tegmental area diminished the stress-induced analgesia in persistent inflammatory pain	3
Effects of non-peptide nociceptin/orphanin FQ receptor ligands on methylphenidate-induced hyperactivity in mice: Implications for bipolar disorders	3
Regulation of the central melanocortin system on energy balance in mammals and birds	3
Semax, synthetic ACTH(4–10) analogue, attenuates behavioural and neurochemical alterations following early-life fluvoxamine exposure in white rats	3
The stress-induced antinociceptive responses to the persistent inflammatory pain involve the orexin receptors in the nucleus accumbens	3